Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC


Welcome to the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, located on the University of Southern California’s Health Sciences Campus.

Our investigators are exploring the normal mechanisms that build, maintain and repair our body systems, to develop knowledge-based approaches for regenerative medicine. Scientists are researching kidney, liver, neural, blood, cardiovascular, skeletal and skin disease models.

The center serves as a hub for USC Stem Cell, which connects researchers in stem cell biology and regenerative medicine across USC.

Postdoctoral fellow Albert Kim receives first Hearst Fellowship

How do you turn stem cells into nephrons, the functional unit of the kidney? Albert D. Kim, PhD, a postdoctoral fellow in the laboratory of Andy McMahon, PhD, is exploring this question with support from a Hearst Fellowship, an award recognizing an exceptional junior postdoctoral fellow pursuing stem cell research at USC.

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Chang Stem Cell Engineering Facility brings gene editing to USC and beyond

Once the stuff of science fiction, genetic engineering is now offered on a fee-for-service basis at USC. On September 19, USC Stem Cell faculty and staff welcomed their supporters, the Chang and Choi families, and nearly 100 of their friends to celebrate the grand opening of the Chang Stem Cell Engineering Facility, located on the second floor of the Eli and Edythe Broad Center (BCC) for Regenerative Medicine and Stem Cell Research at USC on the Health Sciences Campus. Established with a generous gift from the Chang family, the stem cell engineering facility will serve researchers at USC as well as at other institutions.

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Gene summons "surviving cells on deck" to repair the acutely injured kidney

In the kidney, injured cells can be kicked into reparative mode by a gene called Sox9, according to a new paper published in Cell Reports. First author Sanjeev Kumar, MD, PhD, a postdoctoral research associate in the USC Stem Cell laboratory of Andy McMahon, PhD, found that surviving injured cells switch on the Sox9 gene as a response to kidney damage. This regenerates the injured cellular lining of the nephron, the functional unit of the kidney, and repairs the kidney after acute kidney injury (AKI).

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