Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC


Welcome to the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, located on the University of Southern California’s Health Sciences Campus.

Our investigators are exploring the normal mechanisms that build, maintain and repair our body systems, to develop knowledge-based approaches for regenerative medicine. Scientists are researching kidney, liver, neural, blood, cardiovascular, skeletal and skin disease models.

The center serves as a hub for USC Stem Cell, which connects researchers in stem cell biology and regenerative medicine across USC.

USC and Sangamo researchers advance genome editing of blood stem cells

Genome editing techniques for blood stem cells just got better, thanks to a team of researchers at USC and Sangamo BioSciences. In an upcoming study in Nature Biotechnology, co-first authors Colin M. Exline from USC and Jianbin Wang from Sangamo BioSciences describe a new, more efficient way to edit genes in blood-forming or “hematopoietic” stem and progenitor cells (HSPCs).

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Iroquois genes make cartilage cells act "oh so immature"

Arthritis, the leading cause of disability in the U.S., involves the loss of a special type of cartilage cell lining the joints. In a study appearing on the cover of the latest issue of Developmental Cell, first author Amjad Askary — a PhD student in the USC Stem Cell lab of Gage Crump — and his colleagues identify roles for a family of genes, called Iroquois (Irx) genes, in protecting these joint cartilage cells.

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Q&A: USC Stem Cell Ambassador Richard Merkin

USC Stem Cell Ambassador Richard Merkin, MD, is the founder of the Heritage Provider Network, which, under his leadership, became the largest physician-owned and operated integrated delivery system in the United States. He sits on the boards of many colleges and universities, including the Board of Overseers at the Keck School of Medicine of USC, and is known as much for his philanthropy as for his leadership in the health care field. The Merkin Family Foundation recently established four assistant professorships in regenerative medicine at USC.

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