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Paul K Pattengale, MD
Professor of Pathology
CHL MailStop32 Off Campus Los Angeles
+1 323 361 5608


A sensitive LC-MS/MS method for the quantification of urinary 8-iso-prostaglandin F2a (8-iso-PGF2a) including pediatric reference interval. Clin Chim Acta. 2016 Sep 1; 460:128-34. View in: PubMed

Congenital B-lymphoblastic leukemia with a cryptic MLL rearrangement and post-treatment evolution to mixed phenotype acute leukemia. Leuk Res Rep. 2016; 6:29-32. View in: PubMed

Quantification of Glypican 3, Beta-catenin and Claudin-1 Protein Expression in Hepatoblastoma and Pediatric Hepatocellular Carcinoma by Color Deconvolution. Histopathology. 2015 May 4. View in: PubMed

Subcutaneous Panniculitis-like T-cell lymphoma in two pediatric patients: an HIV-positive adolescent and a 4-month-old infant. Fetal Pediatr Pathol. 2013 Jun; 32(3):175-83. View in: PubMed

Simple, Fast, and Simultaneous Detection of Plasma Total Homocysteine, Methylmalonic Acid, Methionine, and 2-Methylcitric Acid Using Liquid Chromatography and Mass Spectrometry (LC/MS/MS). JIMD Rep. 2013; 10:69-78. View in: PubMed

Randomized comparison of low-dose involved-field radiotherapy and no radiotherapy for children with Hodgkin's disease who achieve a complete response to chemotherapy. J Clin Oncol. 2002 Sep 15; 20(18):3765-71. View in: PubMed

Bethesda proposals for classification of lymphoid neoplasms in mice. Blood. 2002 Jul 1; 100(1):246-58. View in: PubMed

Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice. Blood. 2002 Jul 1; 100(1):238-45. View in: PubMed

BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl. Oncogene. 2002 May 9; 21(20):3225-31. View in: PubMed

Assessment of the morphology and significance of the lymph nodal and hepatic lesions produced in rats by the feeding of certain mineral oils and waxes. Proceedings of a pathology workshop held at the Fraunhofer Institute of Toxicology and Aerosol Research Hannover, Germany, May 7-9, 2001. Exp Toxicol Pathol. 2001 Sep; 53(4):247-55. View in: PubMed

The Bcr N-terminal oligomerization domain contributes to the full oncogenicity of P190 Bcr/Abl in transgenic mice. Int J Mol Med. 2001 Apr; 7(4):351-7. View in: PubMed

Crkl enhances leukemogenesis in BCR/ABL P190 transgenic mice. Cancer Res. 2001 Feb 15; 61(4):1398-405. View in: PubMed

Biological characterization of uncleavable plasma membrane-anchored human macrophage colony-stimulating factor. Biochem Biophys Res Commun. 2000 Sep 16; 276(1):304-11. View in: PubMed

Reduced oncogenicity of p190 Bcr/Abl F-actin-binding domain mutants. Blood. 2000 Sep 15; 96(6):2226-32. View in: PubMed

Combination of CD80 and granulocyte-macrophage colony-stimulating factor coexpression by a leukemia cell vaccine: preclinical studies in a murine model recapitulating Philadelphia chromosome-positive acute lymphoblastic leukemia. Hum Gene Ther. 1999 Sep 1; 10(13):2109-22. View in: PubMed

Constitutive HOXA5 expression inhibits erythropoiesis and increases myelopoiesis from human hematopoietic progenitors. Blood. 1999 Jul 15; 94(2):519-28. View in: PubMed

Expression of the human immunodeficiency virus-Tat gene in lymphoid tissues of transgenic mice is associated with B-cell lymphoma. Blood. 1999 Jul 1; 94(1):275-82. View in: PubMed

Multiple factors determine the selection of the ectodomain cleavage site of human cell surface macrophage colony-stimulating factor. Biochemistry. 1998 Dec 22; 37(51):17898-904. View in: PubMed

Immune response to Philadelphia chromosome-positive acute lymphoblastic leukemia induced by expression of CD80, interleukin 2, and granulocyte-macrophage colony-stimulating factor. Hum Gene Ther. 1998 Sep 20; 9(14):2049-62. View in: PubMed

Role of interleukin-6 in the pathogenesis of murine plasmacytoma and human multiple myeloma. Am J Pathol. 1997 Sep; 151(3):647-9. View in: PubMed

Structural requirements for the ectodomain cleavage of human cell surface macrophage colony-stimulating factor. J Biol Chem. 1996 Jul 5; 271(27):16338-43. View in: PubMed

BCR/ABL P210 and P190 cause distinct leukemia in transgenic mice. Blood. 1995 Dec 15; 86(12):4603-11. View in: PubMed

Increased neutrophil respiratory burst in bcr-null mutants. Cell. 1995 Mar 10; 80(5):719-28. View in: PubMed

Leukaemogenesis by the delta Mo + SV Moloney murine leukaemia virus (M-MuLV) variant in E mu pim-1 transgenic mice: high frequency of recombination with a solo endogenous M-MuLV LTR in vivo. J Gen Virol. 1995 Feb; 76 ( Pt 2):347-56. View in: PubMed

Tumours of the lymphohaematopoietic system. IARC Sci Publ. 1994; (111):651-70. View in: PubMed

Establishment and characterization of a human mixed-lineage, T-lymphoid/myeloid cell line (USP-91). Blood. 1993 Sep 15; 82(6):1829-37. View in: PubMed

Quantitative and functional studies of impaired natural killer (NK) cells in patients with myelofibrosis, essential thrombocythemia, and polycythemia vera. I. A potential role for platelet-derived growth factor in defective NK cytotoxicity. Nat Immun. 1993 May-Jun; 12(3):136-51. View in: PubMed

Multiple tumor types appear in a transgenic mouse with the ras oncogene. Am J Pathol. 1993 Apr; 142(4):1199-207. View in: PubMed

Recombination activating gene-1 (RAG-1) expression in all differentiation stages of B-lineage precursor acute lymphoblastic leukemia. Leukemia. 1993 Mar; 7(3):435-40. View in: PubMed

Restricted oncogenicity of BCR/ABL p190 in transgenic mice. Cancer Res. 1992 Aug 15; 52(16):4534-9. View in: PubMed

Clonal development and karyotype evolution during leukemogenesis of BCR/ABL transgenic mice. Blood. 1992 Feb 15; 79(4):1029-36. View in: PubMed

Human bcr-abl gene has a lethal effect on embryogenesis. Transgenic Res. 1991 Dec; 1(1):45-53. View in: PubMed

Inhibition of human natural killer cell activity by platelet-derived growth factor (PDGF). III. Membrane binding studies and differential biological effect of recombinant PDGF isoforms. Scand J Immunol. 1991 May; 33(5):521-32. View in: PubMed

Acute leukaemia in bcr/abl transgenic mice. Nature. 1990 Mar 15; 344(6263):251-3. View in: PubMed

Immunogenetic analysis of bone marrow aspirates in patients with non-Hodgkin lymphomas. Am J Hematol. 1990 Mar; 33(3):160-6. View in: PubMed

Platelet-derived growth factor concentrations in platelet-poor plasma and urine from patients with myeloproliferative disorders. Blood. 1989 Nov 15; 74(7):2330-4. View in: PubMed

Animal models of human disease. Pathology and molecular biology of spontaneous neoplasms occurring in transgenic mice carrying and expressing activated cellular oncogenes. Am J Pathol. 1989 Jul; 135(1):39-61. View in: PubMed

Natural killer cell immunodeficiency in patients with chronic myelogenous leukemia. III. Defective interleukin-2 production by T-helper and natural killer cells. Int J Cancer. 1989 Apr 15; 43(4):591-7. View in: PubMed

Inhibition of human natural killer cell activity by platelet-derived growth factor. II. Membrane binding studies, effects of recombinant IFN-alpha and IL-2, and lack of effect on T cell and antibody-dependent cellular cytotoxicity. J Immunol. 1988 Dec 1; 141(11):4031-8. View in: PubMed

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell. 1988 Jul 1; 54(1):105-15. View in: PubMed

Contributions of recent research to the classification of spontaneous lymphoid cell neoplasms in mice. Crit Rev Toxicol. 1986; 16(3):185-212. View in: PubMed

Multiparameter analyses of spontaneous nonthymic lymphomas occurring in NFS/N mice congenic for ecotropic murine leukemia viruses. Am J Pathol. 1985 Nov; 121(2):349-60. View in: PubMed

Experimental models of lymphoproliferative disease. The mouse as a model for human non-Hodgkin's lymphomas and related leukemias. Am J Pathol. 1983 Nov; 113(2):237-65. View in: PubMed

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