Faculty

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Gordana Raca, MD, PhD
Associate Professor of Clinical Pathology
Pediatrics
CHLA 4650 W. Sunset Blvd. Off Campus Los Angeles

Publications

Diagnostic evaluation of RNA sequencing for the detection of genetic abnormalities associated with Ph-like acute lymphoblastic leukemia (ALL). Leuk Lymphoma. 2016 Nov 17; 1-9. View in: PubMed

Segmental Chromosomal Aberrations in Localized Neuroblastoma Can be Detected in Formalin-Fixed Paraffin-Embedded Tissue Samples and Are Associated With Recurrence. Pediatr Blood Cancer. 2016 Jun; 63(6):1019-23. View in: PubMed

Congenital B-lymphoblastic leukemia with a cryptic MLL rearrangement and post-treatment evolution to mixed phenotype acute leukemia. Leuk Res Rep. 2016; 6:29-32. View in: PubMed

Cerdulatinib, a novel dual SYK/JAK kinase inhibitor, has broad anti-tumor activity in both ABC and GCB types of diffuse large B cell lymphoma. Oncotarget. 2015 Dec 22; 6(41):43881-96. View in: PubMed

T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia. Oncotarget. 2015 Oct 20; 6(32):33410-25. View in: PubMed

Next-generation sequencing reveals clinically actionable molecular markers in myeloid sarcoma. Leukemia. 2015 Oct; 29(10):2113-6. View in: PubMed

Prognosis in Chronic Lymphocytic Leukemia-Reply. JAMA Oncol. 2015 Oct 1; 1(7):988-9. View in: PubMed

Predicting Prognosis in Chronic Lymphocytic Leukemia in the Contemporary Era. JAMA Oncol. 2015 Oct 1; 1(7):965-74. View in: PubMed

RCSD1-ABL2 fusion resulting from a complex chromosomal rearrangement in high-risk B-cell acute lymphoblastic leukemia. Leuk Lymphoma. 2015 Apr; 56(4):1145-7. View in: PubMed

RCSD1-ABL1 Translocation Associated with IKZF1 Gene Deletion in B-Cell Acute Lymphoblastic Leukemia. Case Rep Hematol. 2015; 2015:353247. View in: PubMed

MYC Amplification in Angiosarcoma Arising from an Arteriovenous Graft Site. Case Rep Pathol. 2015; 2015:537297. View in: PubMed

Genomic aberrations in myeloid sarcoma without blood or bone marrow involvement: characterization of formalin-fixed paraffin-embedded samples by chromosomal microarrays. Leuk Res. 2014 Sep; 38(9):1091-6. View in: PubMed

Complex or monosomal karyotype and not blast percentage is associated with poor survival in acute myeloid leukemia and myelodysplastic syndrome patients with inv(3)(q21q26. 2)/t(3;3)(q21;q26. 2): a Bone Marrow Pathology Group study. Haematologica. 2014 May; 99(5):821-9. View in: PubMed

PLZF staining identifies peripheral T-cell lymphomas derived from innate-like T-cells with TRAV1-2-TRAJ33 TCR-a rearrangement. Blood. 2014 Apr 24; 123(17):2742-3. View in: PubMed

MECP2 duplication: possible cause of severe phenotype in females. Am J Med Genet A. 2014 Apr; 164A(4):1029-34. View in: PubMed

The advantage of using SNP array in clinical testing for hematological malignancies--a comparative study of three genetic testing methods. Cancer Genet. 2013 Sep-Oct; 206(9-10):317-26. View in: PubMed

Childhood Apraxia of Speech (CAS) in two patients with 16p11. 2 microdeletion syndrome. Eur J Hum Genet. 2013 Apr; 21(4):455-9. View in: PubMed

The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nat Genet. 2013 Mar; 45(3):242-52. View in: PubMed

Two cases of localized neuroblastoma with multiple segmental chromosomal alterations and metastatic progression. Pediatr Blood Cancer. 2013 Feb; 60(2):332-5. View in: PubMed

A case of pediatric ?/d T-cell malignancy with t(8;14)(q24;q11)/MYC-TCR successfully treated with pulse type chemotherapy followed by stem cell transplant. Leuk Lymphoma. 2013 Feb; 54(2):403-5. View in: PubMed

MLL Rearrangment and EVI1 Deletion in BCR/ABL1 Positive Chronic Myeloid Leukemia. J Assoc Genet Technol. 2013; 39(4):190-4. View in: PubMed

A Unique "Composite" PTLD with Diffuse Large B-Cell and T/Anaplastic Large Cell Lymphoma Components Occurring 17 Years after Transplant. Case Rep Hematol. 2013; 2013:386147. View in: PubMed

Whole-exome sequencing supports genetic heterogeneity in childhood apraxia of speech. J Neurodev Disord. 2013; 5(1):29. View in: PubMed

Novel candidate genes and regions for childhood apraxia of speech identified by array comparative genomic hybridization. Genet Med. 2012 Nov; 14(11):928-36. View in: PubMed

Acute myeloid leukemia: the challenge of unfavorable cytogenetics. Oncology (Williston Park). 2012 Aug; 26(8):724, 726-7. View in: PubMed

Typical renal-coloboma syndrome phenotype in a patient with a submicroscopic deletion of the PAX2 gene. Am J Med Genet A. 2012 Jun; 158A(6):1437-41. View in: PubMed

Phenotype of FOXP2 haploinsufficiency in a mother and son. Am J Med Genet A. 2012 Jan; 158A(1):174-81. View in: PubMed

DNA methylation assay for X-chromosome inactivation in female human iPS cells. Stem Cell Rev. 2011 Nov; 7(4):969-75. View in: PubMed

Chromosomal abnormalities in 2 cases of testicular failure. J Androl. 2011 May-Jun; 32(3):226-31. View in: PubMed

Array comparative genomic hybridization analysis in patients with anophthalmia, microphthalmia, and coloboma. Genet Med. 2011 May; 13(5):437-42. View in: PubMed

Duplication 5q and deletion 9p due to a t(5;9)(q34;p23) in 2 cousins with features of Hunter-McAlpine syndrome and hypothyroidism. Cytogenet Genome Res. 2011; 132(4):233-8. View in: PubMed

Next generation sequencing in research and diagnostics of ocular birth defects. Mol Genet Metab. 2010 Jun; 100(2):184-92. View in: PubMed

Clinical and molecular characterization of overlapping interstitial Xp21-p22 duplications in two unrelated individuals. Am J Med Genet A. 2010 Apr; 152A(4):904-15. View in: PubMed

Mild clinical presentation in a child with prenatally diagnosed 45,X/47,XX,+18 mosaicism. Am J Med Genet A. 2009 Nov; 149A(11):2588-92. View in: PubMed

Array-based comparative genomic hybridization (aCGH) in the genetic evaluation of stillbirth. Am J Med Genet A. 2009 Nov; 149A(11):2437-43. View in: PubMed

Detailed characterization of, and clinical correlations in, 10 patients with distal deletions of chromosome 9p. Genet Med. 2008 Aug; 10(8):599-611. View in: PubMed

Intrachromosomal duplications of 22q11 are not a common cause of isolated coloboma and coloboma with other limited features of cat eye syndrome. Am J Med Genet A. 2008 Feb 1; 146A(3):401-4. View in: PubMed

Paternal deletion 6q24. 3: a new congenital anomaly syndrome associated with intrauterine growth failure, early developmental delay and characteristic facial appearance. Am J Med Genet A. 2008 Feb 1; 146A(3):354-60. View in: PubMed

NSD1 analysis for Sotos syndrome: insights and perspectives from the clinical laboratory. Genet Med. 2005 Oct; 7(8):524-33. View in: PubMed

Deletion analysis of the imprinting center region in patients with Angelman syndrome and Prader-Willi syndrome by real-time quantitative PCR. Genet Test. 2004; 8(4):387-94. View in: PubMed

Progressive dystonia in a 12-year-old boy. Eur J Paediatr Neurol. 2003; 7(2):85-8. View in: PubMed

Expansion of the (CTG)(n) repeat in the 5'-UTR of a reporter gene impedes translation. Nucleic Acids Res. 2000 Oct 15; 28(20):3943-9. View in: PubMed

Trinucleotide repeats affect DNA replication in vivo. Nat Genet. 1997 Nov; 17(3):298-304. View in: PubMed

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