Faculty

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Hyungjin Eoh, PhD
Assistant Professor of Molecular Microbiology & Immunology
Molecular Microbiology and Immunology
ZNI 537 1501 San Pablo Health Sciences Campus Los Angeles

Awards

L.K Whittier Foundation: Whitter Health Sciences Initiative, 2017-2018

Donald E. & Delia B. Baxter Foundation: Junior Faculty Award, 2016-2017

Publications

A Critical Role of Glutamine and Asparagine ?-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus. MBio. 2017 Aug 15; 8(4). View in: PubMed

Metabolic anticipation in Mycobacterium tuberculosis. Nat Microbiol. 2017 May 22; 2:17084. View in: PubMed

Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2017 Mar 14; 114(11):E2225-E2232. View in: PubMed

Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis. ACS Infect Dis. 2016 Dec 09; 2(12):958-968. View in: PubMed

Effects of fluconazole on the metabolomic profile of Candida albicans. J Antimicrob Chemother. 2016 Mar; 71(3):635-40. View in: PubMed

Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis. Cell Rep. 2016 Jan 26; 14(3):572-85. View in: PubMed

Two enzymes with redundant fructose bisphosphatase activity sustain gluconeogenesis and virulence in Mycobacterium tuberculosis. Nat Commun. 2015 Aug 10; 6:7912. View in: PubMed

Metabolomics: a window into the adaptive physiology of Mycobacterium tuberculosis. Tuberculosis (Edinb). 2014 Dec; 94(6):538-43. View in: PubMed

Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis. PLoS Pathog. 2014 May; 10(5):e1004144. View in: PubMed

Methylcitrate cycle defines the bactericidal essentiality of isocitrate lyase for survival of Mycobacterium tuberculosis on fatty acids. Proc Natl Acad Sci U S A. 2014 Apr 01; 111(13):4976-81. View in: PubMed

Allostery and compartmentalization: old but not forgotten. Curr Opin Microbiol. 2014 Apr; 18:23-9. View in: PubMed

Multifunctional essentiality of succinate metabolism in adaptation to hypoxia in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6554-9. View in: PubMed

Co-immunization of plasmid DNA encoding IL-12 and IL-18 with Bacillus Calmette-Guérin vaccine against progressive tuberculosis. Yonsei Med J. 2011 Nov; 52(6):1008-15. View in: PubMed

Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression. PLoS Pathog. 2011 Sep; 7(9):e1002264. View in: PubMed

Regulation of polar peptidoglycan biosynthesis by Wag31 phosphorylation in mycobacteria. BMC Microbiol. 2010 Dec 29; 10:327. View in: PubMed

Expression and validation of D-erythrulose 1-phosphate dehydrogenase from Brucella abortus: a diagnostic reagent for bovine brucellosis. J Vet Diagn Invest. 2010 Jul; 22(4):524-30. View in: PubMed

Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspF. Chem Biol. 2010 Feb 26; 17(2):117-22. View in: PubMed

Expression and characterization of soluble 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from bacterial pathogens. Chem Biol. 2009 Dec 24; 16(12):1230-9. View in: PubMed

The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target. Tuberculosis (Edinb). 2009 Jan; 89(1):1-11. View in: PubMed

Structure-activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase. Bioorg Med Chem Lett. 2008 Oct 01; 18(19):5320-3. View in: PubMed

Chemoenzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol: A substrate for IspE. Tetrahedron Lett. 2008 Jul 21; 49(29-30):4461-4463. View in: PubMed

Characterization of the Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase: potential for drug development. J Bacteriol. 2007 Dec; 189(24):8922-7. View in: PubMed

Antigens secreted from Mycobacterium tuberculosis: identification by proteomics approach and test for diagnostic marker. Proteomics. 2004 Nov; 4(11):3299-307. View in: PubMed

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