Faculty

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Amanda M. Termuhlen, MD
Professor of Clinical Pediatrics
Pediatrics
CHL Mail Stop 54 Off Campus Los Angeles
+1 323 361 2205

Overview

Dr. Termuhlen is medical director of the Jonathan Jaques Children's Cancer Center. She leads a team of pediatric hematology/oncology experts, providing guidance and ensuring a high level of quality is delivered for the coordinated inpatient and outpatient units of the pediatric hematology/oncology programs at Jonathan Jaques Children's Cancer Center (JJCCC).

Dr. Termuhlen is a renowned pediatric hematologist-oncologist who is widely published in peer-reviewed journals. Her clinical research has focused on clinical trials for lymphoma, experimental therapeutics and studies for the late effects of cancer treatment. She leads and expands all pediatric cancer research programs at Miller Children's Hospital Long Beach, including the established Children's Oncology Group.

Dr. Termuhlen received her medical degree from Ohio State University College of Medicine and completed her fellowship in Pediatric Hematology/Oncology at the University of Cincinnati. She is double-board certified in pediatrics and pediatric hematology-oncology.

Publications

Mercaptopurine Ingestion Habits, Red Cell Thioguanine Nucleotide Levels, and Relapse Risk in Children With Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group Study AALL03N1. J Clin Oncol. 2017 May 20; 35(15):1730-1736. View in: PubMed

Comparison of self-report and electronic monitoring of 6MP intake in childhood ALL: a Children's Oncology Group study. Blood. 2017 Apr 06; 129(14):1919-1926. View in: PubMed

Mercaptopurine Ingestion Habits, Red Cell Thioguanine Nucleotide Levels, and Relapse Risk in Children With Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group Study AALL03N1. J Clin Oncol. 2017 Mar 24; JCO2016717579. View in: PubMed

Comparison of self-report and electronic monitoring of 6MP intake in childhood ALL: A Children's Oncology Group study. Blood. 2017 Feb 02. View in: PubMed

Genomic characterization of pediatric B-lymphoblastic lymphoma and B-lymphoblastic leukemia using formalin-fixed tissues. Pediatr Blood Cancer. 2016 Dec 13. View in: PubMed

Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia. Oncotarget. 2016 Nov 08; 7(45):72733-72745. View in: PubMed

Rare Pediatric Non-Hodgkin Lymphomas: A Report From Children's Oncology Group Study ANHL 04B1. Pediatr Blood Cancer. 2016 May; 63(5):794-800. View in: PubMed

A functional polymorphism in the CEBPE gene promoter influences acute lymphoblastic leukemia risk through interaction with the hematopoietic transcription factor Ikaros. Leukemia. 2016 May; 30(5):1194-7. View in: PubMed

Phase 3 trial of defibrotide for the treatment of severe veno-occlusive disease and multi-organ failure. Blood. 2016 Mar 31; 127(13):1656-65. View in: PubMed

The importance of assessing priorities of reproductive health concerns among adolescent and young adult patients with cancer. Cancer. 2015 Aug 1; 121(15):2529-36. View in: PubMed

The importance of assessing priorities of reproductive health concerns among adolescent and young adult patients with cancer. Cancer. 2015 Aug 01; 121(15):2529-36. View in: PubMed

Systemic Exposure to Thiopurines and Risk of Relapse in Children With Acute Lymphoblastic Leukemia: A Children's Oncology Group Study. JAMA Oncol. 2015 Jun 1; 1(3):287-95. View in: PubMed

Systemic Exposure to Thiopurines and Risk of Relapse in Children With Acute Lymphoblastic Leukemia: A Children's Oncology Group Study. JAMA Oncol. 2015 Jun; 1(3):287-95. View in: PubMed

Development of a Spanish language fertility educational brochure for pediatric oncology families. J Pediatr Adolesc Gynecol. 2014 Aug; 27(4):202-9. View in: PubMed

CD19-antigen specific nanoscale liposomal formulation of a SYK P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells. Integr Biol (Camb). 2014 Aug; 6(8):766-80. View in: PubMed

CD19-antigen specific nanoscale liposomal formulation of a SYK P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells. Integr Biol (Camb). 2014 Jul 21; 6(8):766-80. View in: PubMed

Pitfalls of using administrative data sets to describe clinical outcomes in sickle cell disease. Pediatr Blood Cancer. 2013 Dec; 60(12):1936-9. View in: PubMed

Why Healthcare Providers Should Focus on the Fertility of AYA Cancer Survivors: It's Not Too Late! Front Oncol. 2013 Oct 07; 3:248. View in: PubMed

Disseminated lymphoblastic lymphoma in children and adolescents: results of the COG A5971 trial: a report from the Children's Oncology Group. Br J Haematol. 2013 Sep; 162(6):792-801. View in: PubMed

The need for reproductive and sexual health discussions with adolescent and young adult cancer patients. Contraception. 2013 Aug; 88(2):215-20. View in: PubMed

Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia. Blood. 2013 May 23; 121(21):4348-54. View in: PubMed

Why Healthcare Providers Should Focus on the Fertility of AYA Cancer Survivors: It's Not Too Late! Front Oncol. 2013; 3:248. View in: PubMed

SNP association mapping across the extended major histocompatibility complex and risk of B-cell precursor acute lymphoblastic leukemia in children. PLoS One. 2013; 8(8):e72557. View in: PubMed

Constitutive function of the Ikaros transcription factor in primary leukemia cells from pediatric newly diagnosed high-risk and relapsed B-precursor ALL patients. PLoS One. 2013; 8(11):e80732. View in: PubMed

Outcome of newly diagnosed children and adolescents with localized lymphoblastic lymphoma treated on Children's Oncology Group trial A5971: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2012 Dec 15; 59(7):1229-33. View in: PubMed

Metabolic syndrome and endocrine dysfunctions after HSCT in children. Pediatr Transplant. 2012 Dec; 16(8):872-8. View in: PubMed

Twice daily i. v. bolus tacrolimus infusion for GVHD prophylaxis in children undergoing stem cell transplantation. Bone Marrow Transplant. 2012 Nov; 47(11):1415-8. View in: PubMed

Levetiracetam for busulfan-induced seizure prophylaxis in children undergoing hematopoietic stem cell transplantation. Pediatr Blood Cancer. 2012 Oct; 59(4):762-4. View in: PubMed

Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice. Invest New Drugs. 2012 Jun; 30(3):916-26. View in: PubMed

Twenty-five year follow-up of childhood Wilms tumor: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer. 2011 Dec 15; 57(7):1210-6. View in: PubMed

How confident are young adult cancer survivors in managing their survivorship care? A report from the LIVESTRONG™ Survivorship Center of Excellence Network. J Cancer Surviv. 2011 Dec; 5(4):371-81. View in: PubMed

Venous thromboembolism and adolescent and young adult oncology inpatients in US children's hospitals, 2001 to 2008. J Pediatr. 2011 Jul; 159(1):133-7. View in: PubMed

Disseminated Rhizomucor pusillus causing early multiorgan failure during hematopoietic stem cell transplantation for severe aplastic anemia. J Pediatr Hematol Oncol. 2011 Apr; 33(3):235-7. View in: PubMed

Autologous peripheral blood stem cell transplantation in children with refractory or relapsed lymphoma: results of Children's Oncology Group study A5962. Biol Blood Marrow Transplant. 2011 Feb; 17(2):249-58. View in: PubMed

Bilateral burkitt lymphoma of the ovaries: a report of a case in a child with williams syndrome. Case Rep Med. 2011; 2011:327263. View in: PubMed

Bilateral burkitt lymphoma of the ovaries: a report of a case in a child with williams syndrome. Case Report Med. 2011; 2011:327263. View in: PubMed

Adolescent behavior and adult health status in childhood cancer survivors. J Cancer Surviv. 2010 Sep; 4(3):210-7. View in: PubMed

Rare pediatric non-hodgkin lymphoma. Curr Hematol Malig Rep. 2010 Jul; 5(3):163-8. View in: PubMed

Delayed administration of filgrastim (G-CSF) following autologous peripheral blood stem cell transplantation (APBSCT) in pediatric patients does not change time to neutrophil engraftment and reduces use of G-CSF. Pediatr Blood Cancer. 2010 May; 54(5):728-33. View in: PubMed

Hematopoietic stem cell transplantation for refractory or recurrent non-Hodgkin lymphoma in children and adolescents. Biol Blood Marrow Transplant. 2010 Feb; 16(2):223-30. View in: PubMed

Predictors of marriage and divorce in adult survivors of childhood cancers: a report from the Childhood Cancer Survivor Study. Cancer Epidemiol Biomarkers Prev. 2009 Oct; 18(10):2626-35. View in: PubMed

Lymphoma in adolescents and young adults. Semin Oncol. 2009 Oct; 36(5):381-418. View in: PubMed

Prevalence of abnormal bone density of pediatric patients prior to blood or marrow transplant. Pediatr Blood Cancer. 2009 Oct; 53(4):675-7. View in: PubMed

Prognostic significance of interleukin-6 single nucleotide polymorphism genotypes in neuroblastoma: rs1800795 (promoter) and rs8192284 (receptor). Clin Cancer Res. 2009 Aug 15; 15(16):5234-9. View in: PubMed

Primary testicular presentation of ALK-1-negative anaplastic large cell lymphoma in a pediatric patient. J Pediatr Hematol Oncol. 2009 May; 31(5):330-2. View in: PubMed

Tumor immune surveillance defect of X-linked severe combined immunodeficiency is not Epstein-Barr virus specific. Pediatr Blood Cancer. 2008 Nov; 51(5):706-9. View in: PubMed

Mobilization of PML-RARA negative blood stem cells and salvage with autologous peripheral blood stem cell transplantation in children with relapsed acute promyelocytic leukemia. Pediatr Blood Cancer. 2008 Oct; 51(4):521-4. View in: PubMed

Pediatric non-Hodgkin lymphoma. Curr Hematol Malig Rep. 2008 Jul; 3(3):167-73. View in: PubMed

Outcome of children less than three years old at diagnosis with non-metastatic medulloblastoma treated with chemotherapy on the "Head Start" I and II protocols. Pediatr Blood Cancer. 2008 Jun; 50(6):1169-75. View in: PubMed

Spongiform encephalopathy following allogeneic cord blood transplant. Pediatr Transplant. 2008 Feb; 12(1):95-8. View in: PubMed

Pediatric non-Hodgkin's lymphoma. Curr Oncol Rep. 2007 Nov; 9(6):459-65. View in: PubMed

Outcome for young children newly diagnosed with ependymoma, treated with intensive induction chemotherapy followed by myeloablative chemotherapy and autologous stem cell rescue. Pediatr Blood Cancer. 2007 Jul; 49(1):34-40. View in: PubMed

Autologous hematopoietic stem cell transplant with melphalan and thiotepa is safe and feasible in pediatric patients with low normalized glomerular filtration rate. Pediatr Transplant. 2006 Nov; 10(7):830-4. View in: PubMed

Patterns of care among adolescents with malignancy in Ohio. J Pediatr Hematol Oncol. 2006 Jan; 28(1):17-22. View in: PubMed

Mucoepidermoid carcinoma of the parotid gland as a second malignant neoplasm. Pediatr Blood Cancer. 2005 Dec; 45(7):997-1000. View in: PubMed

Once in a lifetime. J Pediatr Hematol Oncol. 2005 Oct; 27(10):505-7. View in: PubMed

Successful treatment of Scedosporium pneumonia with voriconazole during AML therapy and bone marrow transplantation. Med Pediatr Oncol. 2003 Nov; 41(5):494-5. View in: PubMed

Comparison of long-term outcome of children and adolescents with disseminated non-lymphoblastic non-Hodgkin lymphoma treated with COMP or daunomycin-COMP: A report from the Children's Cancer Group. Med Pediatr Oncol. 2001 Nov; 37(5):432-41. View in: PubMed

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