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Amytis Towfighi, MD
Associate Professor of Neurology (Clinical Scholar)
Neurology
Rancho Los Amigos Health Sciences Campus Downey
+1 323 442 5710

Overview

Dr. Towfighi, Associate Professor of Neurology (Clinical Scholar), is Director of Neurological Services and Innovation for Los Angeles County Department of Health Services and Associate Chief Medical Officer and Chair of the Neurology Department at Rancho Los Amigos National Rehabilitation Center. She received her bachelor degree from MIT, MD from Johns Hopkins, completed internship at Massachusetts General Hospital (MGH), Neurology Residency at the Harvard Partners Neurology Program (MGH and Brigham and Women's Hospital), and Neurovascular Fellowship at UCLA.

She has published extensively on sex, race/ethnic, and socioeconomic disparities in stroke, and is currently testing two interventions designed to address disparities in post-stroke care. She received the prestigious Robert G. Siekert New Investigator in Stroke Award from the American Heart Association and Michael S. Pessin Stroke Leadership Prize from the American Academy of Neurology.

She has been involved in three randomized controlled trials (RCTs) of secondary stroke prevention interventions in the Los Angeles County – Department of Health Services (LAC-DHS) public safety-net system: (1) she was the site principal investigator for an American Heart Association-funded multi-center RCT of a chronic-care model based intervention for blood pressure control, SUSTAIN (Systematic Use of STroke Averting Interventions) (Overall PI: Vickrey, UCLA); (2) she is the principal investigator in an American Heart Association-funded RCT of a lifestyle intervention, HEALS (Healthy Eating And Lifestyle after Stroke) (Mentor: Vickrey); and (3) she is the principal investigator (Multiple PI: Towfighi/Vickrey) of an NINDS-funded RCT of a care manager/community health worker team intervention for improving risk factor control after stroke, the “Secondary stroke prevention by Uniting Community and Chronic care model teams Early to End Disparities (SUCCEED)” trial. The SUCCEED intervention is a culturally-tailored, community-based intervention to improve secondary stroke prevention efforts in underserved, socioeconomically disadvantaged communities (primary outcome – blood pressure control). They are enrolling a broad patient population including individuals with transient ischemic attack (TIA), ischemic and hemorrhagic stroke who speak English, Spanish, Cantonese, Mandarin and Korean.

Awards

American Academy of Neurology: Michael S. Pessin Stroke Leadership Prize, 2013

American Heart Association: Robert G. Siekert New Investigator Award in Stroke, 2012

Princeton Stroke Conference: Junior Investigator, 2012

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: Kaiser Permanente Clinical Systems Development Award, 2011

American Neurological Association: Junior Academic Neurologist, 2011

Massachusetts General Hospital: Massachusetts General Hospital Clinical Research Day Neurology Award, 2006

American Heart Association: award conferred by, 2012

American Neurological Association: award conferred by, 2011

Princeton Stroke Conference: award conferred by, 2012

American Academy of Neurology: award conferred by, 2013

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: award conferred by, 2011

Massachusetts General Hospital: award conferred by, 2006

American Heart Association: ORNG Application Instance for Person, 2012

Princeton Stroke Conference: ORNG Application Instance for Person, 2012

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: ORNG Application Instance for Person, 2011

American Academy of Neurology: ORNG Application Instance for Person, 2013

American Neurological Association: ORNG Application Instance for Person, 2011

Massachusetts General Hospital: ORNG Application Instance for Person, 2006

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: full name, 2011

American Neurological Association: full name, 2011

American Academy of Neurology: full name, 2013

Princeton Stroke Conference: full name, 2012

Massachusetts General Hospital: full name, 2006

American Heart Association: full name, 2012

Massachusetts General Hospital: person in primary position, 2006

American Academy of Neurology: Tag Editor, 2013

American Neurological Association: Tag Editor, 2011

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: Tag Editor, 2011

Princeton Stroke Conference: Tag Editor, 2012

American Heart Association: Tag Editor, 2012

American Neurological Association: featured_pub_8, 2011

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: featured_pub_8, 2011

Massachusetts General Hospital: featured_pub_8, 2006

American Heart Association: featured_pub_8, 2012

Princeton Stroke Conference: featured_pub_8, 2012

American Academy of Neurology: featured_pub_8, 2013

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: In The News, 2011

American Heart Association: In The News, 2012

American Academy of Neurology: In The News, 2013

Princeton Stroke Conference: In The News, 2012

Massachusetts General Hospital: In The News, 2006

American Neurological Association: In The News, 2011

Princeton Stroke Conference: ORNG Application URL, 2012

American Neurological Association: ORNG Application URL, 2011

American Academy of Neurology: ORNG Application URL, 2013

American Heart Association: ORNG Application URL, 2012

Massachusetts General Hospital: ORNG Application URL, 2006

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: ORNG Application URL, 2011

Massachusetts General Hospital: sort order, 2006

American Heart Association: sort order, 2012

American Neurological Association: sort order, 2011

Princeton Stroke Conference: sort order, 2012

American Academy of Neurology: sort order, 2013

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: sort order, 2011

Princeton Stroke Conference: featured_pub_10, 2012

Massachusetts General Hospital: featured_pub_10, 2006

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: featured_pub_10, 2011

American Neurological Association: featured_pub_10, 2011

American Heart Association: featured_pub_10, 2012

American Academy of Neurology: featured_pub_10, 2013

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: email address, 2011

American Academy of Neurology: email address, 2013

Princeton Stroke Conference: email address, 2012

American Neurological Association: email address, 2011

American Heart Association: email address, 2012

Massachusetts General Hospital: email address, 2006

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: start date, 2011

Massachusetts General Hospital: start date, 2006

Princeton Stroke Conference: start date, 2012

American Neurological Association: start date, 2011

American Academy of Neurology: start date, 2013

American Heart Association: start date, 2012

American Neurological Association: featured_pub_6, 2011

Massachusetts General Hospital: featured_pub_6, 2006

American Academy of Neurology: featured_pub_6, 2013

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: featured_pub_6, 2011

American Heart Association: featured_pub_6, 2012

Princeton Stroke Conference: featured_pub_6, 2012

American Academy of Neurology: MediaLinks, 2013

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: MediaLinks, 2011

American Heart Association: MediaLinks, 2012

Massachusetts General Hospital: MediaLinks, 2006

American Neurological Association: MediaLinks, 2011

Princeton Stroke Conference: MediaLinks, 2012

American Heart Association: Neurology, 2012

Massachusetts General Hospital: Neurology, 2006

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: Neurology, 2011

American Academy of Neurology: Neurology, 2013

American Neurological Association: Neurology, 2011

Princeton Stroke Conference: Neurology, 2012

American Academy of Neurology: label, 2013

Princeton Stroke Conference: label, 2012

American Neurological Association: label, 2011

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: label, 2011

Massachusetts General Hospital: label, 2006

American Heart Association: label, 2012

American Heart Association: Faculty Rank, 2012

American Academy of Neurology: Faculty Rank, 2013

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: Faculty Rank, 2011

Massachusetts General Hospital: Faculty Rank, 2006

American Neurological Association: Faculty Rank, 2011

Princeton Stroke Conference: Faculty Rank, 2012

American Academy of Neurology: is primary position, 2013

American Neurological Association: is primary position, 2011

American Heart Association: is primary position, 2012

Princeton Stroke Conference: is primary position, 2012

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: is primary position, 2011

Massachusetts General Hospital: is primary position, 2006

American Academy of Neurology: person in primary position, 2013

American Heart Association: person in primary position, 2012

American Neurological Association: person in primary position, 2011

Princeton Stroke Conference: person in primary position, 2012

Massachusetts General Hospital: links, 2006

American Academy of Neurology: links, 2013

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: links, 2011

American Heart Association: links, 2012

American Neurological Association: links, 2011

American Academy of Neurology: featured_pub_12, 2013

Princeton Stroke Conference: featured_pub_12, 2012

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: featured_pub_12, 2011

American Heart Association: featured_pub_12, 2012

American Neurological Association: featured_pub_12, 2011

American Heart Association: has ORNG Application Instance Data, 2012

Massachusetts General Hospital: has ORNG Application Instance Data, 2006

American Neurological Association: has ORNG Application Instance Data, 2011

American Academy of Neurology: has ORNG Application Instance Data, 2013

Massachusetts General Hospital: featured_pub_12, 2006

Princeton Stroke Conference: tags, 2012

American Academy of Neurology: tags, 2013

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: tags, 2011

American Heart Association: tags, 2012

American Neurological Association: tags, 2011

Massachusetts General Hospital: tags, 2006

American Heart Association: Organization, 2012

Massachusetts General Hospital: Organization, 2006

American Academy of Neurology: Organization, 2013

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: Organization, 2011

Massachusetts General Hospital: Tag Editor, 2006

Massachusetts General Hospital: Associate Professor, 2006

Princeton Stroke Conference: Associate Professor, 2012

American Neurological Association: Associate Professor, 2011

American Heart Association: Associate Professor, 2012

American Academy of Neurology: Associate Professor, 2013

Princeton Stroke Conference: ORNG Application Instance Data value, 2012

American Academy of Neurology: ORNG Application Instance Data value, 2013

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: ORNG Application Instance Data value, 2011

American Neurological Association: ORNG Application Instance Data value, 2011

American Heart Association: ORNG Application Instance Data value, 2012

Massachusetts General Hospital: ORNG Application Instance Data value, 2006

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: Associate Professor, 2011

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: Keck School of Medicine of USC, 2011

American Heart Association: Keck School of Medicine of USC, 2012

American Neurological Association: Keck School of Medicine of USC, 2011

American Academy of Neurology: Keck School of Medicine of USC, 2013

Massachusetts General Hospital: Keck School of Medicine of USC, 2006

Princeton Stroke Conference: Keck School of Medicine of USC, 2012

American Heart Association: Featured Publications, 2012

Massachusetts General Hospital: Featured Publications, 2006

American Academy of Neurology: Featured Publications, 2013

Princeton Stroke Conference: Featured Publications, 2012

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: Featured Publications, 2011

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: HR job title, 2011

Massachusetts General Hospital: HR job title, 2006

Princeton Stroke Conference: HR job title, 2012

American Heart Association: HR job title, 2012

American Academy of Neurology: HR job title, 2013

American Neurological Association: HR job title, 2011

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: first name, 2011

Massachusetts General Hospital: first name, 2006

American Academy of Neurology: first name, 2013

American Neurological Association: first name, 2011

Princeton Stroke Conference: first name, 2012

American Heart Association: first name, 2012

American Academy of Neurology: has faculty rank, 2013

Princeton Stroke Conference: has faculty rank, 2012

American Neurological Association: has faculty rank, 2011

American Heart Association: has faculty rank, 2012

Massachusetts General Hospital: has faculty rank, 2006

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: has faculty rank, 2011

American Heart Association: ORNG Application Instance of Application, 2012

California Association of Public Hospitals & Health Systems/California Health Care Safety Net Inst: ORNG Application Instance of Application, 2011

American Neurological Association: ORNG Application Instance of Application, 2011

Massachusetts General Hospital: ORNG Application Instance of Application, 2006

Princeton Stroke Conference: ORNG Application Instance of Application, 2012

American Academy of Neurology: ORNG Application Instance of Application, 2013

Publications

. View in: PubMed

Tale of 2 Health-care Systems: Disparities in Demographic and Clinical Characteristics between 2 Ischemic Stroke Populations in Los Angeles County. J Stroke Cerebrovasc Dis. 2017 Mar 06. View in: PubMed

Randomized controlled trial of a coordinated care intervention to improve risk factor control after stroke or transient ischemic attack in the safety net: Secondary stroke prevention by Uniting Community and Chronic care model teams Early to End Disparities (SUCCEED). BMC Neurol. 2017 Feb 06; 17(1):24. View in: PubMed

Association of Secondhand Smoke With Stroke Outcomes. Stroke. 2016 Oct 11. View in: PubMed

Trends in Transient Ischemic Attack Hospitalizations in the United States. J Am Heart Assoc. 2016 Sep 24; 5(9). View in: PubMed

Comparison of risk scores for the prediction of stroke in African Americans: Findings from the Jackson Heart Study. Am Heart J. 2016 Jul; 177:25-32. View in: PubMed

Key Factors Associated with Major Depression in a National Sample of Stroke Survivors. J Stroke Cerebrovasc Dis. 2016 May; 25(5):1090-5. View in: PubMed

Patterns and Predictors of Blood Pressure Treatment, Control, and Outcomes among Stroke Survivors in the United States. J Stroke Cerebrovasc Dis. 2016 Apr; 25(4):857-65. View in: PubMed

Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation. 2016 Jan 26; 133(4):e38-e360. View in: PubMed

Executive Summary: Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation. 2016 Jan 26; 133(4):447-54. View in: PubMed

Trends in Acute Ischemic Stroke Hospitalizations in the United States. J Am Heart Assoc. 2016; 5(5). View in: PubMed

Association of Insurance Status with Stroke-Related Mortality and Long-term Survival after Stroke. J Stroke Cerebrovasc Dis. 2015 Aug; 24(8):1924-30. View in: PubMed

Systolic blood pressure and mortality after stroke: too low, no go? Stroke. Systolic blood pressure and mortality after stroke: too low, no go? Stroke. 2015 May; 46(5):1307-13. View in: PubMed

Differential effect of B-vitamin therapy by antiplatelet use on risk of recurrent vascular events after stroke. Stroke. 2015 Mar; 46(3):870-3. View in: PubMed

Heart disease and stroke statistics-2015 update: a report from the american heart association. Circulation. 2015 Jan 27; 131(4):e29-e322. View in: PubMed

"Life's Simple 7" and Long-Term Mortality After Stroke. J Am Heart Assoc. 2015; 4(11). View in: PubMed

Guidelines for the prevention of stroke in women: a statement for healthcare professionals from the american heart association/american stroke association. Stroke. 2014 May; 45(5):1545-88. View in: PubMed

Consistency of blood pressure control after ischemic stroke: prevalence and prognosis. Stroke. 2014 May; 45(5):1313-7. View in: PubMed

National Women's Knowledge of Stroke Warning Signs, Overall and by Race/Ethnic Group. Stroke. 2014 Apr; 45(4):1180-2. View in: PubMed

Executive summary: heart disease and stroke statistics--2014 update: a report from the american heart association. Circulation. 2014 Jan 21; 129(3):399-410. View in: PubMed

Factors influencing the decline in stroke mortality: a statement from the american heart association/american stroke association. Stroke. 2014 Jan; 45(1):315-53. View in: PubMed

Homocysteine-Lowering Therapy and Risk of Recurrent Stroke, Myocardial Infarction and Death: The Impact of Age in the VISP Trial. Cerebrovasc Dis. 2014; 37(4):263-7. View in: PubMed

Sex differences in revascularization interventions after acute ischemic stroke. J Stroke Cerebrovasc Dis. 2013 Nov; 22(8):e347-53. View in: PubMed

Fifteen-year trends in awareness of heart disease in women: results of a 2012 American Heart Association national survey. Circulation. 2013 Mar 19; 127(11):1254-63, e1-29. View in: PubMed

Utility of framingham coronary heart disease risk score for predicting cardiac risk after stroke. Stroke. 2012 Nov; 43(11):2942-7. View in: PubMed

Temporal trends in risk of future cardiac events among stroke survivors in the United States. Int J Stroke. 2012 Apr; 7(3):207-12. View in: PubMed

Impact of a healthy lifestyle on all-cause and cardiovascular mortality after stroke in the USA. J Neurol Neurosurg Psychiatry. 2012 Feb; 83(2):146-51. View in: PubMed

Current National Patterns of Comorbid Diabetes among Acute Ischemic Stroke Patients. Cerebrovasc Dis. 2012; 33(5):411-8. View in: PubMed

Insulin resistance, obesity, metabolic syndrome, and lifestyle modification. Continuum (Minneapolis Minn). 2011 Dec; 17(6 2ndary Stroke Prevention):1293-303. View in: PubMed

Assessing adiposity: a scientific statement from the american heart association. Circulation. 2011 Nov 1; 124(18):1996-2019. View in: PubMed

Recent patterns of sex-specific midlife stroke hospitalization rates in the United States. Stroke. 2011 Nov; 42(11):3029-33. View in: PubMed

National gender-specific trends in myocardial infarction hospitalization rates among patients aged 35 to 64 years. Am J Cardiol. 2011 Oct 15; 108(8):1102-7. View in: PubMed

The (pre)hypertension limbo: is it time to lower the treatment bar? Neurology. The (pre)hypertension limbo: is it time to lower the treatment bar? Neurology. 2011 Oct 4; 77(14):1322-3. View in: PubMed

Recent age- and gender-specific trends in mortality during stroke hospitalization in the United States. Int J Stroke. 2011 Oct; 6(5):379-87. View in: PubMed

Sex-specific temporal trends in in-hospital mortality after stroke among middle-age individuals in the United States. Stroke. 2011 Oct; 42(10):2740-5. View in: PubMed

Stroke declines from third to fourth leading cause of death in the United States: historical perspective and challenges ahead. Stroke. 2011 Aug; 42(8):2351-5. View in: PubMed

Efficacy of fibrates for cardiovascular risk reduction in persons with atherogenic dyslipidemia: a meta-analysis. Atherosclerosis. 2011 Aug; 217(2):492-8. View in: PubMed

No time to 'weight': the link between obesity and stroke in women. Womens Health (Lond Engl). 2011 Jul; 7(4):453-63. View in: PubMed

CT and MRI early vessel signs reflect clot composition in acute stroke. Stroke. 2011 May; 42(5):1237-43. View in: PubMed

Randomized, controlled trial of an intervention to enable stroke survivors throughout the Los Angeles County safety net to "stay with the guidelines". Circ Cardiovasc Qual Outcomes. 2011 Mar; 4(2):229-34. View in: PubMed

Persistent sex disparity in midlife stroke prevalence in the United States. Cerebrovasc Dis. 2011; 31(4):322-8. View in: PubMed

Preprocedural basal ganglionic infarction increases the risk of hemorrhagic transformation but not worse outcome following successful recanalization of acute middle cerebral artery occlusions. World Neurosurg. 2010 Dec; 74(6):636-40. View in: PubMed

Pronounced association of elevated serum homocysteine with stroke in subgroups of individuals: a nationwide study. J Neurol Sci. 2010 Nov 15; 298(1-2):153-7. View in: PubMed

Aspirin and recurrent intracerebral hemorrhage in cerebral amyloid angiopathy. Neurology. 2010 Aug 24; 75(8):693-8. View in: PubMed

Weight of the obesity epidemic: rising stroke rates among middle-aged women in the United States. Stroke. 2010 Jul; 41(7):1371-5. View in: PubMed

Therapeutic milestone: stroke declines from the second to the third leading organ- and disease-specific cause of death in the United States. Stroke. 2010 Mar; 41(3):499-503. View in: PubMed

Sex-specific trends in midlife coronary heart disease risk and prevalence. Arch Intern Med. 2009 Oct 26; 169(19):1762-6. View in: PubMed

Basal ganglionic infarction before mechanical thrombectomy predicts poor outcome. Stroke. 2009 Oct; 40(10):3315-20. View in: PubMed

The impact of body mass index on mortality after stroke. Stroke. 2009 Aug; 40(8):2704-8. View in: PubMed

Factors associated with the steep increase in late-midlife stroke occurrence among US men. J Stroke Cerebrovasc Dis. 2008 Jul-Aug; 17(4):165-8. View in: PubMed

Metabolic syndrome and stroke. Curr Diab Rep. 2008 Feb; 8(1):37-41. View in: PubMed

Partial peroxisome proliferator-activated receptor agonist angiotensin receptor blockers. Potential multipronged strategy in stroke prevention. Cerebrovasc Dis. 2008; 26(2):106-12. View in: PubMed

A midlife stroke surge among women in the United States. Neurology. 2007 Nov 13; 69(20):1898-904. View in: PubMed

A computerized algorithm for etiologic classification of ischemic stroke: the Causative Classification of Stroke System. Stroke. 2007 Nov; 38(11):2979-84. View in: PubMed

Treatment and prevention of primary intracerebral hemorrhage. Semin Neurol. 2005 Dec; 25(4):445-52. View in: PubMed

CSF soluble Fas correlates with the severity of HIV-associated dementia. Neurology. 2004 Feb 24; 62(4):654-6. View in: PubMed

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