Faculty

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Arun P. Amar, MD
Associate Professor of Clinical Neurological Surgery
Director of Endovascular Services, Keck Hospital of Usc
Neurological Surgery
GNH 3300 Off Campus Los Angeles
+1 323 226 7421

Overview

Arun Amar, MD, is an associate professor and the Director of Endovascular Neurosurgery at the University of Southern California. He also serves as Stroke Director and Associate Chief of Neurosurgery at the LAC+USC Medical Center. He is one of the few board-certified neurosurgeons who have completed fellowship training in interventional neuroradiology as well.

Dr. Amar graduated summa cum laude with distinction in philosophy from Yale University, where he was elected to the phi beta kappa society. He then graduated at the top of his class from the University of California San Francisco, where he earned the MD with Thesis degree based on original research he performed at their renowned Brain Tumor Research Center. Dr. Amar completed neurosurgery residency and fellowship training at USC. Concurrently, he enrolled in the PhD program in Physiology and Biophysics and was awarded a pre-doctoral fellowship from the Howard Hughes Medical Institute.

After his training, Dr. Amar was recruited back to Yale as Director of Endovascular Neurosurgery. He subsequently worked as a faculty member at Stanford University before returning to the USC School of Medicine.

He has been selected for inclusion in the “Best Doctors in America” database, “America’s Top Surgeons” by the Consumers Research Council of America, Marquis “Who’s Who”, Academic Keys’ “Who's Who in Medicine Higher Education”, Castle Connolly’s “America’s Top Doctors”, Pasadena magazine’s “Top Doctors”, Hollywood Reporter’s “Top Doctors” and US news and World Report “Best Doctors in America” (top 1% of neurosurgeons). He is also a Distinguished Consultant to the National Institute of Medicine and recipient of the Award of Honor of the National Institute of Medicine in the Specialty Field of Neurosurgery.

Dr. Amar’s research and clinical interests include brain and spinal cord injury, aneurysms and vascular malformations, stroke and cerebrovascular disorders, blood-brain-barrier, brain tumors, vagus nerve stimulation, interventional neuroradiology, vertebroplasty, kyphoplasty, stem cell therapy, and gene therapy. In these and other topics, Dr. Amar has authored more than 100 publications in the neurosurgical literature. He has also edited books on spinal cord injury and interventional neuroradiology.

Dr. Amar has led the safety committees of dozens of multicenter randomized clinical trials of cerebrovascular disorders and served on the editorial staff of numerous journals. He has also held numerous leadership positions within organized neurosurgery. He is internationally recognized for his contributions to patient care, research, and education.

Publications

Russin JJ, Kramer DR, Thomas D, Hasson D, Liu CY, Amar AP, Mack WJ, Giannotta SL. The importance of preoperative diagnosis of blister aneurysms. J Clin Neurosci. 2015 Sep; 22(9):1408-12. View in: PubMed

Attenello F, Amar AP, Liu C, Apuzzo ML. Theoretical Basis of Vagus Nerve Stimulation. Prog Neurol Surg. 2015 Sep; 29:20-8. View in: PubMed

Attenello FJ, Ng A, Wen T, Cen SY, Sanossian N, Amar AP, Zada G, Krieger MD, McComb JG, Mack WJ. Racial and socioeconomic disparities in outcomes following pediatric cerebrospinal fluid shunt procedures. J Neurosurg Pediatr. 2015 Jun; 15(6):560-6. View in: PubMed

Attenello FJ, Reid P, Wen T, Cen S, Kim-Tenser M, Sanossian N, Russin J, Amar A, Giannotta S, Mack WJ, Tenser M. Evaluation of time to aneurysm treatment following subarachnoid hemorrhage: comparison of patients treated with clipping versus coiling. J Neurointerv Surg. 2015 Mar 12. View in: PubMed

Torbey MT, Bösel J, Rhoney DH, Rincon F, Staykov D, Amar AP, Varelas PN, Jüttler E, Olson D, Huttner HB, Zweckberger K, Sheth KN, Dohmen C, Brambrink AM, Mayer SA, Zaidat OO, Hacke W, Schwab S. Evidence-based guidelines for the management of large hemispheric infarction : a statement for health care professionals from the neurocritical care society and the german society for neuro-intensive care and emergency medicine. Neurocrit Care. 2015 Feb; 22(1):146-64. View in: PubMed

Pouw AE, Rabin RL, Karanjia R, Bababeygy SR, Amar AP, Sadun AA. Angioarchitectural evolution of clival dural arteriovenous fistulas in two patients. Case Rep Ophthalmol. 2015 Jan-Apr; 6(1):93-100. View in: PubMed

Attenello FJ, Wen T, Cen SY, Ng A, Kim-Tenser M, Sanossian N, Amar AP, Mack WJ. Incidence of "never events" among weekend admissions versus weekday admissions to US hospitals: national analysis. BMJ. 2015; 350:h1460. View in: PubMed

Attenello FJ, Wang K, Wen T, Cen SY, Kim-Tenser M, Amar AP, Sanossian N, Giannotta SL, Mack WJ. Health disparities in time to aneurysm clipping/coiling among aneurysmal subarachnoid hemorrhage patients: a national study. World Neurosurg. 2014 Dec; 82(6):1071-6. View in: PubMed

Wen T, He S, Attenello F, Cen SY, Kim-Tenser M, Adamczyk P, Amar AP, Sanossian N, Mack WJ. The impact of patient age and comorbidities on the occurrence of "never events" in cerebrovascular surgery: an analysis of the Nationwide Inpatient Sample. J Neurosurg. 2014 Sep; 121(3):580-6. View in: PubMed

Wen T, Attenello FJ, He S, Cen Y, Kim-Tenser MA, Sanossian N, Amar AP, Mack WJ. Racial and socioeconomic disparities in incidence of hospital-acquired complications following cerebrovascular procedures. Neurosurgery. 2014 Jul; 75(1):43-50. View in: PubMed

He S, Russin JJ, Adamczyk P, Giannotta SL, Amar AP, Mack WJ. A persistent primitive hypoglossal artery arising from the external carotid artery associated with subarachnoid hemorrhage. World Neurosurg. 2014 Jul-Aug; 82(1-2):239. e1-3. View in: PubMed

Lee B, Mehta VA, Amar AP, Tenser MS, Mack WJ. Transarterial embolization of an anterior fossa cranial base dural arteriovenous fistula. Neurosurg Focus. 2014 Jul; 37(1 Suppl):1. View in: PubMed

Lee B, Mehta VA, Mack WJ, Tenser MS, Amar AP. Balloon-assisted transarterial embolization of type 1 spinal dural arteriovenous fistula. Neurosurg Focus. 2014 Jul; 37(1 Suppl):1. View in: PubMed

Attenello FJ, Adamczyk P, Wen G, He S, Zhang K, Russin JJ, Sanossian N, Amar AP, Mack WJ. Racial and socioeconomic disparities in access to mechanical revascularization procedures for acute ischemic stroke. J Stroke Cerebrovasc Dis. 2014 Feb; 23(2):327-34. View in: PubMed

Ferreira R, Santos T, Amar A, Gong A, Chen TC, Tahara SM, Giannotta SL, Hofman FM. Argonaute-2 Promotes miR-18a Entry in Human Brain Endothelial Cells. J Am Heart Assoc. 2014; 3(3). View in: PubMed

Ferreira R, Santos T, Amar A, Tahara SM, Chen TC, Giannotta SL, Hofman FM. MicroRNA-18a Improves Human Cerebral Arteriovenous Malformation Endothelial Cell Function. Stroke. 2014 Jan; 45(1):293-7. View in: PubMed

Adamczyk P, Attenello F, Wen G, He S, Russin J, Sanossian N, Amar AP, Mack WJ. Mechanical thrombectomy in acute stroke: utilization variances and impact of procedural volume on inpatient mortality. J Stroke Cerebrovasc Dis. 2013 Nov; 22(8):1263-9. View in: PubMed

Russin JJ, Attenello FJ, Amar AP, Liu CY, Apuzzo ML, Hsieh PC. Computed tomography for clearance of cervical spine injury in the unevaluable patient. World Neurosurg. 2013 Sep-Oct; 80(3-4):405-13. View in: PubMed

Tuchman A, Khalessi AA, Attenello FJ, Amar AP, Zada G. Delayed cavernous carotid artery pseudoaneurysm caused by absorbable plate following transsphenoidal surgery: case report and review of the literature. J Neurol Surg Rep. 2013 Jun; 74(1):10-6. View in: PubMed

Amar AP. Neurosurgery in India: past as prologue. World Neurosurg. 2013 May-Jun; 79(5-6):613-4. View in: PubMed

Adamczyk P, He S, Amar AP, Mack WJ. Medical Management of Cerebral Vasospasm following Aneurysmal Subarachnoid Hemorrhage: A Review of Current and Emerging Therapeutic Interventions. Neurol Res Int. 2013; 2013:462491. View in: PubMed

Mills JN, Mehta V, Russin J, Amar AP, Rajamohan A, Mack WJ. Advanced imaging modalities in the detection of cerebral vasospasm. Neurol Res Int. 2013; 2013:415960. View in: PubMed

Kramer DR, Winer JL, Pease BA, Amar AP, Mack WJ. Cerebral vasospasm in traumatic brain injury. Neurol Res Int. 2013; 2013:415813. View in: PubMed

Mehta V, Russin J, Spirtos A, He S, Adamczyk P, Amar AP, Mack WJ. Matrix Metalloproteinases in Cerebral Vasospasm following Aneurysmal Subarachnoid Hemorrhage. Neurol Res Int. 2013; 2013:943761. View in: PubMed

Amar AP, Newell DW. Vascular fistulas of the brain and spinal cord. Neurosurg Focus. 2012 May; 32(5):Introduction. View in: PubMed

Adamczyk P, Amar AP, Mack WJ, Larsen DW. Recurrence of "cured" dural arteriovenous fistulas after Onyx embolization. Neurosurg Focus. 2012 May; 32(5):E12. View in: PubMed

Amar AP. Controversies in the neurosurgical management of cerebellar hemorrhage and infarction. Neurosurg Focus. 2012 Apr; 32(4):E1. View in: PubMed

Amar AP. Brain and vascular imaging of acute stroke. World Neurosurg. 2011 Dec; 76(6 Suppl):S3-8. View in: PubMed

Tenser MS, Amar AP, Mack WJ. Mechanical Thrombectomy for Acute Ischemic Stroke Using the MERCI Retriever and Penumbra Aspiration Systems. World Neurosurg. 2011 Dec; 76(6 Suppl):S16-23. View in: PubMed

Yashar P, Amar AP, Giannotta SL, Yu C, Pagnini PG, Liu CY, Apuzzo ML. Cerebral arteriovenous malformations: issues of the interplay between stereotactic radiosurgery and endovascular surgical therapy. World Neurosurg. 2011 May-Jun; 75(5-6):638-47. View in: PubMed

Levy ML, Levy KM, Hoff D, Amar AP, Park MS, Conklin JM, Baird L, Apuzzo ML. Vagus nerve stimulation therapy in patients with autism spectrum disorder and intractable epilepsy: results from the vagus nerve stimulation therapy patient outcome registry. J Neurosurg Pediatr. 2010 Jun; 5(6):595-602. View in: PubMed

Hoh DJ, Hoh BL, Amar AP, Wang MY. Shape memory alloys: metallurgy, biocompatibility, and biomechanics for neurosurgical applications. Neurosurgery. 2009 May; 64(5 Suppl 2):199-214; discussion 214-5. View in: PubMed

Heller AC, Amar AP, Liu CY, Apuzzo ML. Surgery of the mind and mood: a mosaic of issues in time and evolution. Neurosurgery. 2008 Jun; 62(6 Suppl 3):921-40. View in: PubMed

Amar AP, Apuzzo ML, Liu CY. Vagus nerve stimulation therapy after failed cranial surgery for intractable epilepsy: results from the vagus nerve stimulation therapy patient outcome registry. Neurosurgery. 2008 Feb; 62 Suppl 2:506-13. View in: PubMed

Amar AP. Vagus nerve stimulation for the treatment of intractable epilepsy. Expert Rev Neurother. 2007 Dec; 7(12):1763-73. View in: PubMed

Amar AP, Teitelbaum GP, Larsen DW. A novel technique and new grading scale for the embolization of cerebral vascular malformations. Neurosurgery. 2006 Nov; 59(5 Suppl 3):S158-62; discussion S3-13. View in: PubMed

Heller AC, Amar AP, Liu CY, Apuzzo ML. Surgery of the mind and mood: a mosaic of issues in time and evolution. Neurosurgery. 2006 Oct; 59(4):720-33; discussion 733-9. View in: PubMed

Ozturk AK, Nahed BV, Bydon M, Bilguvar K, Goksu E, Bademci G, Guclu B, Johnson MH, Amar A, Lifton RP, Gunel M. Molecular genetic analysis of two large kindreds with intracranial aneurysms demonstrates linkage to 11q24-25 and 14q23-31. Stroke. 2006 Apr; 37(4):1021-7. View in: PubMed

Nicholls TP, Shoemaker WC, Wo CC, Gruen JP, Amar A, Dang AB. Survival, hemodynamics, and tissue oxygenation after head trauma. J Am Coll Surg. 2006 Jan; 202(1):120-30. View in: PubMed

Aryan HE, Amar AP, Ozgur BM, Levy ML. Gunshot wounds to the spine in adolescents. Neurosurgery. 2005 Oct; 57(4):748-52; discussion 748-52. View in: PubMed

Nahed BV, DiLuna ML, Morgan T, Ocal E, Hawkins AA, Ozduman K, Kahle KT, Chamberlain A, Amar AP, Gunel M. Hypertension, age, and location predict rupture of small intracranial aneurysms. Neurosurgery. 2005 Oct; 57(4):676-83; discussion 676-83. View in: PubMed

Amar AP, Larsen DW, Teitelbaum GP. Percutaneous spinal interventions. Neurosurg Clin N Am. 2005 Jul; 16(3):561-8, vii. View in: PubMed

Chakrabarti I, Amar AP, Couldwell W, Weiss MH. Long-term neurological, visual, and endocrine outcomes following transnasal resection of craniopharyngioma. J Neurosurg. 2005 Apr; 102(4):650-7. View in: PubMed

Amar AP, Apuzzo ML, Liu CY. Vagus nerve stimulation therapy after failed cranial surgery for intractable epilepsy: results from the vagus nerve stimulation therapy patient outcome registry. Neurosurgery. 2004 Nov; 55(5):1086-93. View in: PubMed

Levy ML, Meltzer HS, Hughes S, Aryan HE, Yoo K, Amar AP. Hydrocephalus in children with middle fossa arachnoid cysts. J Neurosurg. 2004 Aug; 101(1 Suppl):25-31. View in: PubMed

Amar AP, Larsen DW, Teitelbaum GP. Use of a screw-syringe injector for cement delivery during kyphoplasty: technical report. Neurosurgery. 2003 Aug; 53(2):380-2; discussion 383. View in: PubMed

Amar AP, Aryan HE, Meltzer HS, Levy ML. Neonatal subgaleal hematoma causing brain compression: report of two cases and review of the literature. Neurosurgery. 2003 Jun; 52(6):1470-4; discussion 1474. View in: PubMed

Amar AP, Zlokovic BV, Apuzzo ML. Endovascular restorative neurosurgery: a novel concept for molecular and cellular therapy of the nervous system. Neurosurgery. 2003 Feb; 52(2):402-12; discussion 412-3. View in: PubMed

Amar AP, Apuzzo ML. Vagus nerve stimulation therapy for patients with persistent seizures after epilepsy surgery. Stereotact Funct Neurosurg. 2003; 80(1-4):9-13. View in: PubMed

Amar AP, Weiss MH. Pituitary anatomy and physiology. Neurosurg Clin N Am. 2003 Jan; 14(1):11-23, v. View in: PubMed

Amar AP, Couldwell WT, Chen JC, Weiss MH. Predictive value of serum prolactin levels measured immediately after transsphenoidal surgery. J Neurosurg. 2002 Aug; 97(2):307-14. View in: PubMed

Amar AP, Teitelbaum GP, Giannotta SL, Larsen DW. Covered stent-graft repair of the brachiocephalic arteries: technical note. Neurosurgery. 2002 Jul; 51(1):247-52; discussion 252-3. View in: PubMed

Apuzzo ML, Liker MA, Amar AP. Honored guest presentation: neurorestoration and the emergence of molecular and cellular neurosurgery. Clin Neurosurg. 2002; 49:274-315. View in: PubMed

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