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Bo Han, PhD
Associate Professor of Research Surgery
BMT 302A Health Sciences Campus Los Angeles
+1 323 442 2242


Kim JH, Ko ES, Lim Y, Lee KS, Han BK, Ko EY, Hahn SY, Nam SJ. Breast Cancer Heterogeneity: MR Imaging Texture Analysis and Survival Outcomes. Radiology. 2016 Oct 4; 160261. View in: PubMed

Choi HY, Ko ES, Han BK, Kim EJ, Kim SM, Lim Y, Kim RB. Prognostic Significance of Transverse Relaxation Rate (R2*) in Blood Oxygenation Level-Dependent Magnetic Resonance Imaging in Patients with Invasive Breast Cancer. PLoS One. 2016; 11(7):e0158500. View in: PubMed

Ko ES, Han H, Han BK, Kim SM, Kim RB, Lee GW, Park YH, Nam SJ. Prognostic Significance of a Complete Response on Breast MRI in Patients Who Received Neoadjuvant Chemotherapy According to the Molecular Subtype. Korean J Radiol. 2015 Sep-Oct; 16(5):986-95. View in: PubMed

Hoang BX, Shaw DG, Han B, Fang JY, Nimni M. Acidosis and Formaldehyde Secretion as a Possible Pathway of Cancer Pain and Options for Improved Cancer Pain Control. J Pain Palliat Care Pharmacother. 2015 Sep; 29(3):276-80. View in: PubMed

Hoang BX, Han B, Shaw DG, Nimni M. Zinc as a possible preventive and therapeutic agent in pancreatic, prostate, and breast cancer. Eur J Cancer Prev. 2015 Aug 27. View in: PubMed

Tian M, Han B, Tan H, You C. Preparation and characterization of galactosylated alginate-chitosan oligomer microcapsule for hepatocytes microencapsulation. Carbohydr Polym. 2014 Nov 4; 112:502-11. View in: PubMed

Tan S, Fang JY, Yang Z, Nimni ME, Han B. The synergetic effect of hydrogel stiffness and growth factor on osteogenic differentiation. Biomaterials. 2014 Jul; 35(20):5294-306. View in: PubMed

Ahn HS, Kim SM, Jang M, Yun BL, Kim B, Ko ES, Han BK, Chang JM, Yi A, Cho N, Moon WK, Choi HY. A new full-field digital mammography system with and without the use of an advanced post-processing algorithm: comparison of image quality and diagnostic performance. Korean J Radiol. 2014 May; 15(3):305-12. View in: PubMed

Han B, Yang Z, Fang JY, Kuwahara K, Nimni M, Thanasukarn J, Tayag C. The effects of heparin binding proteins in platelet releasate on bone formation. Tissue Eng Part A. 2014 Apr; 20(7-8):1263-70. View in: PubMed

Ko ES, Han BK, Kim RB, Cho EY, Ahn S, Nam SJ, Ko EY, Shin JH, Hahn SY. Apparent diffusion coefficient in estrogen receptor-positive invasive ductal breast carcinoma: correlations with tumor-stroma ratio. Radiology. 2014 Apr; 271(1):30-7. View in: PubMed

Fang J, Yang Z, Tan S, Tayag C, Nimni ME, Urata M, Han B. Injectable gel graft for bone defect repair. Regen Med. 2014 Jan; 9(1):41-51. View in: PubMed

Fang JY, Tan SJ, Yang Z, Tayag C, Han B. Tumor bioengineering using a transglutaminase crosslinked hydrogel. PLoS One. 2014; 9(8):e105616. View in: PubMed

B. Han · N. Blasetti · L. A. Ugartemendia · D. Vincens · S. Ferraris · M. Nimni · G. A. Moviglia. Homologous demineralised bone matrix (DBM) associated to autologous adipose mesenchymal stromal cells (aMSC) and efefcter cells (EC) against DBM induce bone tissue formation at two week post treatment of experimental jaw lesions in pigs. Cytotherapy. 2014; 16(4):S95-96. View in: PubMed

Su SF, Chang YW, Andreu-Vieyra C, Fang JY, Yang Z, Han B, Lee AS, Liang G. miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer. Oncogene. 2013 Sep 26; 32(39):4694-701. View in: PubMed

Ko ES, Han BK, Kim SM, Ko EY, Jang M, Lyou CY, Chang JM, Moon WK, Kim RB. Comparison of new and established full-field digital mammography systems in diagnostic performance. Korean J Radiol. 2013 Mar-Apr; 14(2):164-70. View in: PubMed

Tian M, Yang Z, Kuwahara K, Nimni ME, Wan C, Han B. Delivery of demineralized bone matrix powder using a thermogelling chitosan carrier. Acta Biomater. 2012 Feb; 8(2):753-62. View in: PubMed

Kuwahara K, Fang JY, Yang Z, Han B. Enzymatic crosslinking and degradation of gelatin as a switch for bone morphogenetic protein-2 activity. Tissue Eng Part A. 2011 Dec; 17(23-24):2955-64. View in: PubMed

Kuwahara K, Yang Z, Slack GC, Nimni ME, Han B. Cell delivery using an injectable and adhesive transglutaminase-gelatin gel. Tissue Eng Part C Methods. 2010 Aug; 16(4):609-18. View in: PubMed

Armstrong JK, Han B, Kuwahara K, Yang Z, Magyar CE, Dry SM, Atti E, Tetradis S, Fisher TC. The effect of three hemostatic agents on early bone healing in an animal model. BMC Surg. 2010; 10:37. View in: PubMed

Han B, Woodell-May J, Ponticiello M, Yang Z, Nimni M. The effect of thrombin activation of platelet-rich plasma on demineralized bone matrix osteoinductivity. J Bone Joint Surg Am. 2009 Jun; 91(6):1459-70. View in: PubMed

Yeh TT, Wen ZH, Lee HS, Lee CH, Yang Z, Jean YH, Wu SS, Nimni ME, Han B. Intra-articular injection of collagenase induced experimental osteoarthritis of the lumbar facet joint in rats. Eur Spine J. 2008 May; 17(5):734-42. View in: PubMed

Kim SM, Ko EY, Han BK, Shin JH, Kang SS, Nam SJ, Cho EY. Metastatic thymoma of the breast. Korean J Radiol. 2008 Jan-Feb; 9(1):80-3. View in: PubMed

Han B, Yang Z, Nimni M. Effects of gamma irradiation on osteoinduction associated with demineralized bone matrix. J Orthop Res. 2008 Jan; 26(1):75-82. View in: PubMed

Yeh TT, Wu SS, Lee CH, Wen ZH, Lee HS, Yang Z, Nimni ME, Han B. The short-term therapeutic effect of recombinant human bone morphogenetic protein-2 on collagenase-induced lumbar facet joint osteoarthritis in rats. Osteoarthritis Cartilage. 2007 Dec; 15(12):1357-66. View in: PubMed

Kim E, Choe YH, Han BK, Kim SM, Kim JS, Park SW, Sung J. Right ventricular fat infiltration in asymptomatic subjects: observations from ECG-gated 16-slice multidetector CT. J Comput Assist Tomogr. 2007 Jan-Feb; 31(1):22-8. View in: PubMed

Cha JH, Moon WK, Cho N, Kim SM, Park SH, Han BK, Choe YH, Park JM, Im JG. Characterization of benign and malignant solid breast masses: comparison of conventional US and tissue harmonic imaging. Radiology. 2007 Jan; 242(1):63-9. View in: PubMed

Nimni ME, Han B, Cordoba F. Are we getting enough sulfur in our diet? Nutr Metab (Lond). 2007; 4:24. View in: PubMed

Cho N, Moon WK, Cha JH, Kim SM, Han BK, Kim EK, Kim MH, Chung SY, Choi HY, Im JG. Differentiating benign from malignant solid breast masses: comparison of two-dimensional and three-dimensional US. Radiology. 2006 Jul; 240(1):26-32. View in: PubMed

Nimni ME, Cordoba F, Strates B and Han B. Chondroitin sulfate and sulfur containing condroprotective agents: Is there a basis for their Pharmacological action? . Curr Rheum Rev. 2006; 2:137-149. View in: PubMed

Kim S, Nimni ME, Yang Z, Han B. Chitosan/gelatin-based films crosslinked by proanthocyanidin. J Biomed Mater Res B Appl Biomater. 2005 Nov; 75(2):442-50. View in: PubMed

Han B, Yang Z, Nimni M. Effects of moisture and temperature on the osteoinductivity of demineralized bone matrix. J Orthop Res. 2005 Jul; 23(4):855-61. View in: PubMed

Han B, Nimni ME. Transdermal delivery of amino acids and antioxidants enhance collagen synthesis: in vivo and in vitro studies. Connect Tissue Res. 2005; 46(4-5):251-7. View in: PubMed

Han B, Tang B, Nimni ME. Quantitative and sensitive in vitro assay for osteoinductive activity of demineralized bone matrix. J Orthop Res. 2003 Jul; 21(4):648-54. View in: PubMed

Han B, Jaurequi J, Tang BW, Nimni ME. Proanthocyanidin: a natural crosslinking reagent for stabilizing collagen matrices. J Biomed Mater Res A. 2003 Apr 1; 65(1):118-24. View in: PubMed

Han B, Tang B, Nimni ME. Combined effects of phosphatidylcholine and demineralized bone matrix on bone induction. Connect Tissue Res. 2003; 44(3-4):160-6. View in: PubMed

Andrades JA, Han B, Nimni ME, Ertl DC, Simpkins RJ, Arrabal MP, Becerra J. A modified rhTGF-beta1 and rhBMP-2 are effective in initiating a chondro-osseous differentiation pathway in bone marrow cells cultured in vitro. Connect Tissue Res. 2003; 44(3-4):188-97. View in: PubMed

Chun J, Tuan TL, Han B, Vangsness CT, Nimni ME. Cultures of ligament fibroblasts in fibrin matrix gel. Connect Tissue Res. 2003; 44(2):81-7. View in: PubMed

Han B, Perelman N, Tang B, Hall F, Shors EC, Nimni ME. Collagen-targeted BMP3 fusion proteins arrayed on collagen matrices or porous ceramics impregnated with Type I collagen enhance osteogenesis in a rat cranial defect model. J Orthop Res. 2002 Jul; 20(4):747-55. View in: PubMed

Hall FL, Han B, Kundu RK, Yee A, Nimni ME, Gordon EM. Phenotypic differentiation of TGF-beta1-responsive pluripotent premesenchymal prehematopoietic progenitor (P4 stem) cells from murine bone marrow. J Hematother Stem Cell Res. 2001 Apr; 10(2):261-71. View in: PubMed

Andrades JA, Han B, Becerra J, Sorgente N, Hall FL, Nimni ME. A recombinant human TGF-beta1 fusion protein with collagen-binding domain promotes migration, growth, and differentiation of bone marrow mesenchymal cells. Exp Cell Res. 1999 Aug 1; 250(2):485-98. View in: PubMed

Collagen and collagen-glycosaminoglycan matrices as carriers for growth factors. Journal of Chemical Sciences. 1999; 111(1):283-289. View in: PubMed

Han B, Hall FL, Nimni ME. Refolding of a recombinant collagen-targeted TGF-beta2 fusion protein expressed in Escherichia coli. Protein Expr Purif. 1997 Nov; 11(2):169-78. View in: PubMed

Gordon EM, Skotzko M, Kundu RK, Han B, Andrades J, Nimni M, Anderson WF, Hall FL. Capture and expansion of bone marrow-derived mesenchymal progenitor cells with a transforming growth factor-beta1-von Willebrand's factor fusion protein for retrovirus-mediated delivery of coagulation factor IX. Hum Gene Ther. 1997 Jul 20; 8(11):1385-94. View in: PubMed

Nimni ME, Myers D, Ertl D, Han B. Factors which affect the calcification of tissue-derived bioprostheses. J Biomed Mater Res. 1997 Jun 15; 35(4):531-7. View in: PubMed

Coats WD, Whittaker P, Cheung DT, Currier JW, Han B, Faxon DP. Collagen content is significantly lower in restenotic versus nonrestenotic vessels after balloon angioplasty in the atherosclerotic rabbit model. Circulation. 1997 Mar 4; 95(5):1293-300. View in: PubMed

Coats WD, Cheung DT, Han B, Currier JW, Faxon DP. Balloon angioplasty significantly increases collagen content but does not alter collagen subtype I/III ratios in the atherosclerotic rabbit iliac model. J Mol Cell Cardiol. 1996 Feb; 28(2):441-6. View in: PubMed

Andrades JA, Nimni ME, Han B, Ertl DC, Hall FL, Becerra J. Type I collagen combined with a recombinant TGF-beta serves as a scaffold for mesenchymal stem cells. Int J Dev Biol. 1996; Suppl 1:107S-108S. View in: PubMed

Tuan TL, Cheung DT, Wu LT, Yee A, Gabriel S, Han B, Morton L, Nimni ME, Hall FL. Engineering, expression and renaturation of targeted TGF-beta fusion proteins. Connect Tissue Res. 1996; 34(1):1-9. View in: PubMed

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