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Christianne Norton Heck, MD, MMM
Professor of Clinical Neurology
Co Director, USC Center For Neurorestoration
Medical Director, USC Comprehensive Epilepsy Center
HCC 3rd Floor Room 3000 Health Sciences Campus Los Angeles
+1 323 442 8364


Dr. Christianne Heck is a neurologist in Los Angeles, California and is affiliated with multiple hospitals in the area, including Keck Hospital of USC and University of Southern California-Norris Cancer Hospital. She received her medical degree from Keck School of Medicine of USC and has been in practice for 23 years. She is one of 37 doctors at Keck Hospital of USC and one of 7 at University of Southern California-Norris Cancer Hospital who specialize in Neurology.


Liu C, Russin J, Heck C, Kawata K, Adiga R, Yen W, Lambert J, Stear B, Law M, Marquez Y, Crino P, Millett D, Langford D. Dysregulation of PINCH signaling in mesial temporal epilepsy. J Clin Neurosci. 2016 Nov 9. View in: PubMed

Klaes C, Kellis S, Aflalo T, Lee B, Pejsa K, Shanfield K, Hayes-Jackson S, Aisen M, Heck C, Liu C, Andersen RA. Hand Shape Representations in the Human Posterior Parietal Cortex. J Neurosci. 2015 Nov 18; 35(46):15466-76. View in: PubMed

Nune G, DeGiorgio C, Heck C. Neuromodulation in the Treatment of Epilepsy. Curr Treat Options Neurol. 2015 Oct; 17(10):375. View in: PubMed

Lee B, Zubair MN, Marquez YD, Lee DM, Kalayjian LA, Heck CN, Liu CY. A Single-Center Experience with the NeuroPace RNS System: A Review of Techniques and Potential Problems. World Neurosurg. 2015 Sep; 84(3):719-26. View in: PubMed

King-Stephens D, Mirro E, Weber PB, Laxer KD, Van Ness PC, Salanova V, Spencer DC, Heck CN, Goldman A, Jobst B, Shields DC, Bergey GK, Eisenschenk S, Worrell GA, Rossi MA, Gross RE, Cole AJ, Sperling MR, Nair DR, Gwinn RP, Park YD, Rutecki PA, Fountain NB, Wharen RE, Hirsch LJ, Miller IO, Barkley GL, Edwards JC, Geller EB, Berg MJ, Sadler TL, Sun FT, Morrell MJ. Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography. Epilepsia. 2015 Jun; 56(6):959-67. View in: PubMed

Aflalo T, Kellis S, Klaes C, Lee B, Shi Y, Pejsa K, Shanfield K, Hayes-Jackson S, Aisen M, Heck C, Liu C, Andersen RA. Neurophysiology. Decoding motor imagery from the posterior parietal cortex of a tetraplegic human. Science. 2015 May 22; 348(6237):906-10. View in: PubMed

Hsiao MC, Yu PN, Song D, Liu CY, Heck CN, Millett D, Berger TW. An in vitro seizure model from human hippocampal slices using multi-electrode arrays. J Neurosci Methods. 2015 Apr 15; 244:154-63. View in: PubMed

Bergey GK, Morrell MJ, Mizrahi EM, Goldman A, King-Stephens D, Nair D, Srinivasan S, Jobst B, Gross RE, Shields DC, Barkley G, Salanova V, Olejniczak P, Cole A, Cash SS, Noe K, Wharen R, Worrell G, Murro AM, Edwards J, Duchowny M, Spencer D, Smith M, Geller E, Gwinn R, Skidmore C, Eisenschenk S, Berg M, Heck C, Van Ness P, Fountain N, Rutecki P, Massey A, O'Donovan C, Labar D, Duckrow RB, Hirsch LJ, Courtney T, Sun FT, Seale CG. Long-term treatment with responsive brain stimulation in adults with refractory partial seizures. Neurology. 2015 Feb 24; 84(8):810-7. View in: PubMed

Soss J, Heck C, Murray D, Markovic D, Oviedo S, Corrale-Leyva G, Gordon S, Kealey C, DeGiorgio C. A prospective long-term study of external trigeminal nerve stimulation for drug-resistant epilepsy. Epilepsy Behav. 2015 Jan; 42:44-7. View in: PubMed

A testbed to explore the optimal electrical stimulation parameters for suppressing inter-ictal spikes in human hippocampal slices. Conf Proc IEEE Eng Med Biol Soc. 2014 Aug; 2014:5792-5. View in: PubMed

Unstable periodic orbits in human epileptic hippocampal slices. Conf Proc IEEE Eng Med Biol Soc. 2014 Aug; 2014:5800-3. View in: PubMed

Heck CN, King-Stephens D, Massey AD, Nair DR, Jobst BC, Barkley GL, Salanova V, Cole AJ, Smith MC, Gwinn RP, Skidmore C, Van Ness PC, Bergey GK, Park YD, Miller I, Geller E, Rutecki PA, Zimmerman R, Spencer DC, Goldman A, Edwards JC, Leiphart JW, Wharen RE, Fessler J, Fountain NB, Worrell GA, Gross RE, Eisenschenk S, Duckrow RB, Hirsch LJ, Bazil C, O'Donovan CA, Sun FT, Courtney TA, Seale CG, Morrell MJ. Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial. Epilepsia. 2014 Mar; 55(3):432-41. View in: PubMed

Hensley-Judge H, Quigg M, Barbaro NM, Newman SA, Ward MM, Chang EF, Broshek DK, Lamborn KR, Laxer KD, Garcia P, Heck CN, Kondziolka D, Beach R, Salanova V, Goodman R. Visual field defects after radiosurgery for mesial temporal lobe epilepsy. Epilepsia. 2013 Aug; 54(8):1376-80. View in: PubMed

DeGiorgio CM, Soss J, Cook IA, Markovic D, Gornbein J, Murray D, Oviedo S, Gordon S, Corralle-Leyva G, Kealey CP, Heck CN. Randomized controlled trial of trigeminal nerve stimulation for drug-resistant epilepsy. Neurology. 2013 Feb 26; 80(9):786-91. View in: PubMed

Berger T, Song D, Chan R, Shin D, Marmarelis V, Hampson R, Sweatt A, Heck C, Liu C, Wills J, Lacoss J, Granacki J, Gerhardt G, Deadwyler S. Role of the hippocampus in memory formation : restorative encoding memory integration neural device as a cognitive neural prosthesis. IEEE Pulse. 2012 Sep; 3(5):17-22. View in: PubMed

Hsiao MC, Yu PN, Song D, Liu CY, Heck CN, Millett D, Berger TW. Spatio-temporal inter-ictal activity recorded from human epileptic hippocampal slices. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:5166-9. View in: PubMed

Herzog AG, Fowler KM, Sperling MR, Liporace JD, Kalayjian LA, Heck CN, Krauss GL, Dworetzky BA, Pennell PB. Variation of seizure frequency with ovulatory status of menstrual cycles. Epilepsia. 2011 Oct; 52(10):1843-8. View in: PubMed

Herzog AG, Smithson SD, Fowler KM, Krishnamurthy KB, Sundstrom D, Kalayjian LA, Heck CN, Oviedo S, Correl-Leyva G, Garcia E, Gleason KA, Dworetzky BA. Premenstrual dysphoric disorder in women with epilepsy: relationships to potential epileptic, antiepileptic drug, and reproductive endocrine factors. Epilepsy Behav. 2011 Aug; 21(4):391-6. View in: PubMed

Heck C, Helmers SL, DeGiorgio CM. Vagus nerve stimulation therapy, epilepsy, and device parameters: scientific basis and recommendations for use. Neurology. 2002 Sep 24; 59(6 Suppl 4):S31-7. View in: PubMed

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