Christopher Haiman, ScD

Christopher Haiman, ScD, is a professor of preventive medicine at the Keck School of Medicine of USC and AFLAC Chair in Cancer Research. He also leads the Cancer Epidemiology Program at USC Norris Comprehensive Cancer Center and the Epidemiology and Genetics division in the Department of Preventive Medicine. Dr. Haiman is a genetic epidemiologist whose research is focused on exploring racial and ethnic disparities in cancer risk, with the goal of developing approaches to reduce these disparities. He is co-principal investigator of the Multiethnic Cohort (MEC), a large prospective study of cancer in primarily non-European ancestry populations (n>215,000) that has been the foundation of his scientific investigation into the genetic risk of cancer, initially through genome-wide association studies (GWAS) and more recently in large-scale genomic consortia in minority populations that employ next-generation sequencing technology. In addition to these leadership and administrative research positions, he has vast experience in directing large consortia and is currently the scientific leader of the African Ancestry Prostate Cancer Consortium (AAPC). He has also served as a steering committee member for numerous NIH consortia, including the NCI GAME-ON Consortium, NHGRI Population Architecture Using Genomics and Epidemiology Consortium (PAGE), NHGRI Gene Environment Association Studies (GENEVA) Consortium and the NCI Breast and Prostate Cancer Cohort Consortium (BPC3). He is also the principal investigator of the RESPOND African-American prostate cancer initiative. He has co-authored more than 450 peer-reviewed publications, with many in prominent journals, including Nature Genetics, The New England Journal of Medicine and Journal of the National Cancer Institute.

• 0: a contralateral breast cancer risk prediction model developed and validated in ~? 200000 patients. Breast Cancer Res. 2022 10 21; 24(1):69.. View in PubMed
• 0: a contralateral breast cancer risk prediction model developed and validated in? 200000 patients. Breast Cancer Res. 2022 Nov 22; 24(1):82.. View in PubMed
• Thyroid Cancer Survival in the Multiethnic Cohort Study Int J Environ Res Public Health. 2024 Mar 10; 21(3). . View in PubMed
• Identification of Genes with Rare Loss of Function Variants Associated with Aggressive Prostate Cancer and Survival Eur Urol Oncol. 2024 Mar 07. . View in PubMed
• Combining magnetic resonance imaging with a multi-ancestry polygenic risk score to improve identification of clinically-significant prostate cancer JNCI Cancer Spectr. 2024 Mar 01. . View in PubMed
• Age at lung cancer diagnosis in females versus males who never smoke by race and ethnicity Br J Cancer. 2024 Feb 22. . View in PubMed
• Genetic drivers of heterogeneity in type 2 diabetes pathophysiology Nature. 2024 Feb 19. . View in PubMed
• Epigenome-wide association study of total nicotine equivalents in multiethnic current smokers from three prospective cohorts Am J Hum Genet. 2024 Feb 16. . View in PubMed
• Racial and Ethnic Differences in the Population-Attributable Fractions of Alzheimer Disease and Related Dementias Neurology. 2024 Feb 13; 102(3):e208116. . View in PubMed
• Differences in polygenic score distributions in European ancestry populations: implications for breast cancer risk prediction medRxiv. 2024 Feb 13. . View in PubMed
• The Association of Alcohol Outlet Density with Alcohol Intake: The Multiethnic Cohort J Stud Alcohol Drugs. 2024 Feb 09. . View in PubMed
• Novel breast cancer susceptibility loci under linkage peaks identified in African ancestry consortia Hum Mol Genet. 2024 Jan 23. . View in PubMed
• Adaption and National Validation of a Tool for Predicting Mortality from Other Causes Among Men with Nonmetastatic Prostate Cancer Eur Urol Oncol. 2024 Jan 02. . View in PubMed
• Increasing risk of hepatocellular carcinoma with successive generations in the United States among Mexican American adults: The Multiethnic Cohort Cancer. 2024 01; 130(2):267-275. . View in PubMed
• Avocado and Guacamole Consumption and Colorectal Cancer Risk: The Multiethnic Cohort Study Nutr Cancer. 2024; 76(4):372-378. . View in PubMed
• Adiposity, Weight Change, and Urinary Melatonin Levels among Men in the Multiethnic Cohort Cancer Epidemiol Biomarkers Prev. 2024 01 09; 33(1):136-142. . View in PubMed
• The accuracy of polygenic score models for anthropometric traits and Type II Diabetes in the Native Hawaiian Population medRxiv. 2023 Dec 28. . View in PubMed
• Polygenic Risk Score Modifies Prostate Cancer Risk of Pathogenic Variants in Men of African Ancestry Cancer Res Commun. 2023 Dec 14; 3(12):2544-2550. . View in PubMed
• Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants Nat Genet. 2023 Dec; 55(12):2065-2074. . View in PubMed
• Risk Model-Based Lung Cancer Screening and Racial and Ethnic Disparities in the US JAMA Oncol. 2023 Dec 01; 9(12):1640-1648. . View in PubMed
• Association of Endocrine Disrupting Chemicals With the Metabolic Syndrome Among Women in the Multiethnic Cohort Study J Endocr Soc. 2023 Nov 02; 7(12):bvad136. . View in PubMed
• Germline Sequencing Analysis to Inform Clinical Gene Panel Testing for Aggressive Prostate Cancer JAMA Oncol. 2023 Nov 01; 9(11):1514-1524. . View in PubMed
• Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves cross-ancestry prediction medRxiv. 2023 Oct 30. . View in PubMed
• No Association of Trichomonas vaginalis Seropositivity with Advanced Prostate Cancer Risk in the Multiethnic Cohort: A Nested Case-Control Study Cancers (Basel). 2023 Oct 28; 15(21). . View in PubMed
• Heterogeneous genetic architectures and evolutionary genomics of prostate cancer in Sub-Saharan Africa Res Sq. 2023 Oct 12. . View in PubMed
• Association of Obesity and Type 2 Diabetes with Non-Hodgkin Lymphoma: The Multiethnic Cohort Cancer Epidemiol Biomarkers Prev. 2023 Oct 02; 32(10):1348-1355. . View in PubMed
• Correction: Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes Leukemia. 2023 Oct; 37(10):2142. . View in PubMed
• Assessing efficiency of fine-mapping obesity-associated variants through leveraging ancestry architecture and functional annotation using PAGE and UKBB cohorts Hum Genet. 2023 Oct; 142(10):1477-1489. . View in PubMed
• ANO7 African-ancestral genomic diversity and advanced prostate cancer Prostate Cancer Prostatic Dis. 2023 Sep 25. . View in PubMed
• MUSSEL: Enhanced Bayesian Polygenic Risk Prediction Leveraging Information across Multiple Ancestry Groups bioRxiv. 2023 Sep 21. . View in PubMed
• Particulate matter, traffic-related air pollutants, and circulating C-reactive protein levels: The Multiethnic Cohort Study Environ Pollut. 2023 Sep 01; 332:121962. . View in PubMed
• WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE medRxiv. 2023 Aug 22. . View in PubMed
• Alcohol intake and endogenous sex hormones in women: meta-analysis of cohort studies and Mendelian randomization Res Sq. 2023 Aug 16. . View in PubMed
• Racial, Ethnic, and Socioeconomic Differences in a Deficit Accumulation Frailty Index in the Multiethnic Cohort Study J Gerontol A Biol Sci Med Sci. 2023 Jul 08; 78(7):1246-1257. . View in PubMed
• Understanding the genetic complexity of puberty timing across the allele frequency spectrum medRxiv. 2023 Jun 20. . View in PubMed
• Genetically adjusted PSA levels for prostate cancer screening Nat Med. 2023 Jun; 29(6):1412-1423. . View in PubMed
• Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry medRxiv. 2023 May 15. . View in PubMed
• Transcriptome-Wide Association Analysis Identifies Novel Candidate Susceptibility Genes for Prostate-Specific Antigen Levels in Men Without Prostate Cancer medRxiv. 2023 May 05. . View in PubMed
• Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics bioRxiv. 2023 Apr 18. . View in PubMed
• Multi-ancestry genome-wide study in >25 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications. medRxiv. 2023 Mar 31. . View in PubMed
• Biochemical activity induced by a germline variation in KLK3 (PSA) associates with cellular function and clinical outcome in prostate cancer Res Sq. 2023 Mar 28. . View in PubMed
• Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries Nat Genet. 2023 Mar; 55(3):519-520. . View in PubMed
• Association of the CHEK2 c1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival. Res Sq. 2023 Feb 13. . View in PubMed
• Whole exome sequencing and replication for breast cancer among Hispanic/Latino women identifies FANCM as a susceptibility gene for estrogen-receptor-negative breast cancer medRxiv. 2023 Jan 28. . View in PubMed
• Combining Asian-European Genome-Wide Association Studies of Colorectal Cancer Improves Risk Prediction Across Race and Ethnicity medRxiv. 2023 Jan 19. . View in PubMed
• Erratum: Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium HGG Adv. 2023 Jan 12; 4(1):100149. . View in PubMed
• Atopic allergic conditions and prostate cancer risk and survival in the Multiethnic Cohort study Br J Cancer. 2023 10; 129(6):974-981. . View in PubMed
• Association of the CHEK2 c1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival. Cancer Med. 2023 08; 12(15):16142-16162. . View in PubMed
• Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights Eur Urol. 2023 07; 84(1):127-137. . View in PubMed
• The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes Diabetologia. 2023 07; 66(7):1273-1288. . View in PubMed
• Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry Eur Urol. 2023 07; 84(1):13-21. . View in PubMed
• Associations of minor histocompatibility antigens with outcomes following allogeneic hematopoietic cell transplantation Am J Hematol. 2023 06; 98(6):940-950. . View in PubMed
• Interethnic Differences in Bladder Cancer Incidence and the Association between Type 2 Diabetes and Bladder Cancer in the Multiethnic Cohort Study Cancer Res Commun. 2023 05; 3(5):755-762. . View in PubMed
• Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals Nat Genet. 2023 04; 55(4):549-558. . View in PubMed
• Validation and Comparison of Nutrient Intakes from Two Dietary Questionnaires Developed for the Multiethnic Cohort StudyJ Acad Nutr Diet. 2023 04; 123(4):655-663. e1. . View in PubMed
• A Healthy Lifestyle in Men at Increased Genetic Risk for Prostate Cancer Eur Urol. 2023 04; 83(4):343-351. . View in PubMed
• Modifying effects of race and ethnicity and APOE on the association of physical activity with risk of Alzheimer’s disease and related dementias Alzheimers Dement. 2023 02; 19(2):507-517. . View in PubMed
• Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries Nat Genet. 2023 01; 55(1):89-99. . View in PubMed
• Androgen receptor binding sites enabling genetic prediction of mortality due to prostate cancer in cancer-free subjects Nat Commun. 2023 08 23; 14(1):4863. . View in PubMed
• The impact of COVID-19 on cancer screening and treatment in older adults: The Multiethnic Cohort Study Elife. 2023 06 27; 12. . View in PubMed
• Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics Am J Hum Genet. 2023 11 02; 110(11):1853-1862. . View in PubMed
• Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry Genome Med. 2023 01 26; 15(1):7. . View in PubMed
• Change in the inflammatory potential of diet over 10 years and subsequent mortality: the Multiethnic Cohort Study Br J Nutr. 2023 01 14; 129(1):157-165. . View in PubMed
• Clonal hematopoiesis and risk of prostate cancer in large samples of European ancestry men Hum Mol Genet. 2023 01 13; 32(3):489-495. . View in PubMed
• White Rice Consumption and Risk of Colorectal Cancer Among Japanese Americans: The Multiethnic Cohort Study J Epidemiol. 2023 04 05; 33(4):170-176. . View in PubMed
• Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations Nat Commun. 2023 10 02; 14(1):6147. . View in PubMed
• Genome-wide association study of abdominal MRI-measured visceral fat: The multiethnic cohort adiposity phenotype study PLoS One. 2023; 18(1):e0279932. . View in PubMed
• Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry Am J Hum Genet. 2023 07 06; 110(7):1200-1206. . View in PubMed
• ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk Clin Cancer Res. 2023 08 15; 29(16):3037-3050. . View in PubMed
• Contralateral Breast Cancer Risk Among Carriers of Germline Pathogenic Variants in ATM, BRCA1, BRCA2, CHEK2, and PALB2 J Clin Oncol. 2023 03 20; 41(9):1703-1713. . View in PubMed
• Circulating insulin-like growth factors and risks of overall, aggressive and early-onset prostate cancer: a collaborative analysis of 20 prospective studies and Mendelian randomization analysis Int J Epidemiol. 2023 02 08; 52(1):71-86. . View in PubMed
• A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry Breast Cancer Res. 2023 08 09; 25(1):93. . View in PubMed
• Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C Cancer Res. 2023 08 01; 83(15):2557-2571. . View in PubMed
• Shared graft-versus-leukemia minor histocompatibility antigens in DISCOVeRY-BMT Blood Adv. 2023 05 09; 7(9):1635-1649. . View in PubMed
• RE: Polygenic risk of any, metastatic, and fatal prostate cancer in the Million Veteran Program J Natl Cancer Inst. 2023 03 09; 115(3):341-342. . View in PubMed
• Genetic Susceptibility to Nonalcoholic Fatty Liver Disease and Risk for Pancreatic Cancer: Mendelian Randomization Cancer Epidemiol Biomarkers Prev. 2023 09 01; 32(9):1265-1269. . View in PubMed
• Inverted genomic regions between reference genome builds in humans impact imputation accuracy and decrease the power of association testing HGG Adv. 2023 01 12; 4(1):100159. . View in PubMed
• Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study Br J Sports Med. 2022 Oct; 56(20):1157-1170. . View in PubMed
• Genetic Risk of Second Primary Cancer in Breast Cancer Survivors: The Multiethnic Cohort Study Cancer Res. 2022 Sep 16; 82(18):3201-3208. . View in PubMed
• Risk of Alzheimer’s disease and related dementia by sex and race/ethnicity: The Multiethnic Cohort Study Alzheimers Dement. 2022 Sep; 18(9):1625-1634. . View in PubMed
• Incorporating progesterone receptor expression into the PREDICT breast prognostic model Eur J Cancer. 2022 Sep; 173:178-193. . View in PubMed
• Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk Eur J Hum Genet. 2022 May; 30(5):630-631. . View in PubMed
• Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium HGG Adv. 2022 Apr 14; 3(2):100099. . View in PubMed
• Urinary 6-sulfatoxymelatonin Levels and Prostate Cancer Risk among Men in the Multiethnic Cohort Cancer Epidemiol Biomarkers Prev. 2022 Mar 01; 31(3):688-691. . View in PubMed
• Diet quality and all-cause and cancer-specific mortality in cancer survivors and non-cancer individuals: the Multiethnic Cohort Study Eur J Nutr. 2022 Mar; 61(2):925-933. . View in PubMed
• Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes Leukemia. 2022 12; 36(12):2835-2844. . View in PubMed
• A saturated map of common genetic variants associated with human height Nature. 2022 10; 610(7933):704-712. . View in PubMed
• Deconstructing, Addressing, and Eliminating Racial and Ethnic Inequities in Prostate Cancer Care Eur Urol. 2022 10; 82(4):341-351. . View in PubMed
• Genome-Wide Epistatic Interaction between DEF1B and APOL1 High-Risk Genotypes for Chronic Kidney Disease Clin J Am Soc Nephrol. 2022 10; 17(10):1522-1525. . View in PubMed
• Large-scale genome-wide association study of coronary artery disease in genetically diverse populations Nat Med. 2022 08; 28(8):1679-1692. . View in PubMed
• Evaluating breast cancer predisposition genes in women of African ancestry Genet Med. 2022 07; 24(7):1468-1475. . View in PubMed
• Modifiable Factors and Incident Gout Across Ethnicity Within a Large Multiethnic Cohort of Older Adults J Rheumatol. 2022 05; 49(5):504-512. . View in PubMed
• Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation Nat Genet. 2022 05; 54(5):560-572. . View in PubMed
• A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry Eur Urol. 2022 05; 81(5):458-462. . View in PubMed
• Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score Prostate Cancer Prostatic Dis. 2022 04; 25(4):755-761. . View in PubMed
• A genome-wide gene-based gene-environment interaction study of breast cancer in more than 90,000 women Cancer Res Commun. 2022 04; 2(4):211-219. . View in PubMed
• Prognostic utility of self-reported sarcopenia (SARC-F) in the Multiethnic Cohort J Cachexia Sarcopenia Muscle. 2022 04; 13(2):987-1002. . View in PubMed
• Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study Diabetologia. 2022 03; 65(3):477-489. . View in PubMed
• Polygenic risk modeling for prediction of epithelial ovarian cancer risk Eur J Hum Genet. 2022 03; 30(3):349-362. . View in PubMed
• Contributions of Social Factors to Disparities in Prostate Cancer Risk Profiles among Black Men and Non-Hispanic White Men with Prostate Cancer in California Cancer Epidemiol Biomarkers Prev. 2022 02; 31(2):404-412. . View in PubMed
• Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits Am J Hum Genet. 2022 04 07; 109(4):669-679. . View in PubMed
• Genome-wide interaction analysis of menopausal hormone therapy use and breast cancer risk among 62,370 women Sci Rep. 2022 04 13; 12(1):6199. . View in PubMed
• Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci Breast Cancer Res. 2022 04 12; 24(1):27. . View in PubMed
• Joint Associations of Race, Ethnicity, and Socioeconomic Status With Mortality in the Multiethnic Cohort Study JAMA Netw Open. 2022 04 01; 5(4):e226370. . View in PubMed
• Evaluation of a Multiethnic Polygenic Risk Score Model for Prostate Cancer J Natl Cancer Inst. 2022 05 09; 114(5):771-774. . View in PubMed
• Enrichment analyses identify shared associations for 25 quantitative traits in over 600,000 individuals from seven diverse ancestries Am J Hum Genet. 2022 05 05; 109(5):871-884. . View in PubMed
• Cancer Mortality Patterns by Birthplace and Generation Status of Mexican Latinos: The Multiethnic Cohort J Natl Cancer Inst. 2022 07 11; 114(7):959-968. . View in PubMed
• Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations Elife. 2022 07 08; 11. . View in PubMed
• Circulating free testosterone and risk of aggressive prostate cancer: Prospective and Mendelian randomisation analyses in international consortia Int J Cancer. 2022 10 01; 151(7):1033-1046. . View in PubMed
• Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: a cross-ancestry approach Hum Mol Genet. 2022 09 10; 31(18):3133-3143. . View in PubMed
• Rare germline copy number variants (CNVs) and breast cancer risk Commun Biol. 2022 01 18; 5(1):65. . View in PubMed
• Association of Prostate-Specific Antigen Levels with Prostate Cancer Risk in a Multiethnic Population: Stability Over Time and Comparison with Polygenic Risk Score Cancer Epidemiol Biomarkers Prev. 2022 12 05; 31(12):2199-2207. . View in PubMed
• Plant-based dietary patterns defined by a priori indices and colorectal cancer risk by sex and race/ethnicity: the Multiethnic Cohort Study BMC Med. 2022 11 29; 20(1):430. . View in PubMed
• Common variants in breast cancer risk loci predispose to distinct tumor subtypes Breast Cancer Res. 2022 01 04; 24(1):2. . View in PubMed
• A transcriptome-wide association study identifies novel candidate susceptibility genes for prostate cancer risk Int J Cancer. 2022 01 01; 150(1):80-90. . View in PubMed
• Distinct Reproductive Risk Profiles for Intrinsic-Like Breast Cancer Subtypes: Pooled Analysis of Population-Based Studies J Natl Cancer Inst. 2022 12 08; 114(12):1706-1719. . View in PubMed
• Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa Genome Biol. 2022 09 13; 23(1):194. . View in PubMed
• Genomics and phenomics of body mass index reveals a complex disease network Nat Commun. 2022 12 29; 13(1):7973. . View in PubMed
• Cholesterol lowering drug use and breast cancer survival: the Multiethnic Cohort Study Breast Cancer Res Treat. 2021 Nov; 190(1):165-173. . View in PubMed
• Novel genetic variants associated with mortality after unrelated donor allogeneic hematopoietic cell transplantation EClinicalMedicine. 2021 Oct; 40:101093. . View in PubMed
• Hum Genet. 2021 Oct; 140(10):1449-1457. . View in PubMed
• Race, ethnicity, community-level socioeconomic factors, and risk of COVID-19 in the United States and the United Kingdom EClinicalMedicine. 2021 Aug; 38:101029. . View in PubMed
• Large-scale cross-cancer fine-mapping of the 5p1533 region reveals multiple independent signals. HGG Adv. 2021 Jul 08; 2(3):100041. . View in PubMed
• Comparison of the Prevalence of Pathogenic Variants in Cancer Susceptibility Genes in Black Women and Non-Hispanic White Women With Breast Cancer in the United States JAMA Oncol. 2021 Jul 01; 7(7):1045-1050. . View in PubMed
• Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies? Cancers (Basel). 2021 May 14; 13(10).. View in PubMed
• Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers Nat Commun. 2021 May 14; 12(1):2986. . View in PubMed
• Diet Quality and Risk of Lung Cancer in the Multiethnic Cohort Study Nutrients. 2021 May 12; 13(5). . View in PubMed
• Genetic discovery and risk characterization in type 2 diabetes across diverse populations HGG Adv. 2021 Apr 08; 2(2). . View in PubMed
• Techniques and Outcomes of MRI-TRUS Fusion Prostate Biopsy Curr Urol Rep. 2021 Mar 22; 22(4):27. . View in PubMed
• Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction Nat Genet. 2021 Mar; 53(3):413. . View in PubMed
• Alcohol Intake and Alcohol-SNP Interactions Associated with Prostate Cancer Aggressiveness J Clin Med. 2021 Feb 02; 10(3). . View in PubMed
• Novel strategy for disease risk prediction incorporating predicted gene expression and DNA methylation data: a multi-phased study of prostate cancer Cancer Commun (Lond). 2021 12; 41(12):1387-1397. . View in PubMed
• Mendelian randomisation study of smoking exposure in relation to breast cancer risk Br J Cancer. 2021 10; 125(8):1135-1145. . View in PubMed
• Association of Genetic Risk Score With NAFLD in An Ethnically Diverse Cohort Hepatol Commun. 2021 10; 5(10):1689-1703. . View in PubMed
• Combined Effect of a Polygenic Risk Score and Rare Genetic Variants on Prostate Cancer Risk Eur Urol. 2021 08; 80(2):134-138. . View in PubMed
• Genetic insights into biological mechanisms governing human ovarian ageing Nature. 2021 08; 596(7872):393-397. . View in PubMed
• Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer Prostate Cancer Prostatic Dis. 2021 06; 24(2):532-541. . View in PubMed
• Prediagnostic Antibody Responses to Fusobacterium nucleatum Proteins Are Not Associated with Risk of Colorectal Cancer in a Large US. Consortium. Cancer Epidemiol Biomarkers Prev. 2021 06; 30(6):1279-1282. . View in PubMed
• Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium Cancer Epidemiol Biomarkers Prev. 2021 04; 30(4):623-642. . View in PubMed
• CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers Br J Cancer. 2021 02; 124(4):842-854. . View in PubMed
• The impact of global and local Polynesian genetic ancestry on complex traits in Native Hawaiians PLoS Genet. 2021 02; 17(2):e1009273. . View in PubMed
• Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction Nat Genet. 2021 01; 53(1):65-75. . View in PubMed
• Risk of Breast Cancer Among Carriers of Pathogenic Variants in Breast Cancer Predisposition Genes Varies by Polygenic Risk Score J Clin Oncol. 2021 08 10; 39(23):2564-2573. . View in PubMed
• Association of Anthropometric Measures With the Risk of Prostate Cancer in the Multiethnic Cohort Am J Epidemiol. 2021 09 01; 190(9):1770-1783. . View in PubMed
• KLK3 SNP-SNP interactions for prediction of prostate cancer aggressiveness Sci Rep. 2021 04 29; 11(1):9264. . View in PubMed
• Genetic variants in anti-Müllerian hormone-related genes and breast cancer risk: results from the AMBER consortium Breast Cancer Res Treat. 2021 Jan; 185(2):469-478. . View in PubMed
• Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis Sci Rep. 2021 10 05; 11(1):19787. . View in PubMed
• Germline Pathogenic Variants in Cancer Predisposition Genes Among Women With Invasive Lobular Carcinoma of the Breast J Clin Oncol. 2021 12 10; 39(35):3918-3926. . View in PubMed
• A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers Nat Commun. 2021 02 17; 12(1):1078. . View in PubMed
• Risk of breast cancer and prediagnostic urinary excretion of bisphenol A, triclosan and parabens: The Multiethnic Cohort Study Int J Cancer. 2021 10 01; 149(7):1426-1434. . View in PubMed
• Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk J Natl Cancer Inst. 2021 03 01; 113(3):329-337. . View in PubMed
• Prognostic impact of pre-transplant chromosomal aberrations in peripheral blood of patients undergoing unrelated donor hematopoietic cell transplant for acute myeloid leukemia Sci Rep. 2021 07 22; 11(1):15004. . View in PubMed
• Genome-wide association study of pancreatic fat: The Multiethnic Cohort Adiposity Phenotype Study PLoS One. 2021; 16(7):e0249615. . View in PubMed
• Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility Front Genet. 2021; 12:554948. . View in PubMed
• Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women Nat Commun. 2021 07 07; 12(1):4198. . View in PubMed
• Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element Am J Hum Genet. 2021 07 01; 108(7):1190-1203. . View in PubMed
• Urinary phthalate exposures and risk of breast cancer: the Multiethnic Cohort study Breast Cancer Res. 2021 04 06; 23(1):44. . View in PubMed
• Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry Am J Hum Genet. 2021 04 01; 108(4):564-582. . View in PubMed
• Pre-HCT mosaicism increases relapse risk and lowers survival in acute lymphoblastic leukemia patients post-unrelated HCT Blood Adv. 2021 01 12; 5(1):66-70. . View in PubMed
• A Population-Based Study of Genes Previously Implicated in Breast Cancer N Engl J Med. 2021 02 04; 384(5):440-451. . View in PubMed
• Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer Int J Cancer. 2021 01 15; 148(2):307-319. . View in PubMed
• Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes Nat Commun. 2021 06 09; 12(1):3505. . View in PubMed
• Risk of Late-Onset Breast Cancer in Genetically Predisposed Women J Clin Oncol. 2021 11 01; 39(31):3430-3440. . View in PubMed
• Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry J Natl Cancer Inst. 2021 09 04; 113(9):1168-1176. . View in PubMed
• Germline Sequencing DNA Repair Genes in 5545 Men With Aggressive and Nonaggressive Prostate Cancer J Natl Cancer Inst. 2021 05 04; 113(5):616-625. . View in PubMed
• Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment Breast Cancer Res. 2021 08 18; 23(1):86. . View in PubMed
• The CHEK2 Variant C349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor. Cancers (Basel). 2020 Nov 04; 12(11). . View in PubMed
• Association of Combined Sero-Positivity to Helicobacter pylori and Streptococcus gallolyticus with Risk of Colorectal Cancer Microorganisms. 2020 Oct 30; 8(11). . View in PubMed
• Genome-Wide Association Study of Liver Fat: The Multiethnic Cohort Adiposity Phenotype Study Hepatol Commun. 2020 Aug; 4(8):1112-1123. . View in PubMed
• Prediction of contralateral breast cancer: external validation of risk calculators in 20 international cohorts Breast Cancer Res Treat. 2020 Jun; 181(2):423-434. . View in PubMed
• Replication and Genetic Risk Score Analysis for Pancreatic Cancer in a Diverse Multiethnic Population Cancer Epidemiol Biomarkers Prev. 2020 12; 29(12):2686-2692. . View in PubMed
• Racial Differences in Helicobacter pylori CagA Sero-prevalence in a Consortium of Adult Cohorts in the United States Cancer Epidemiol Biomarkers Prev. 2020 10; 29(10):2084-2092. . View in PubMed
• Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci Mol Psychiatry. 2020 10; 25(10):2392-2409. . View in PubMed
• Variability in Cytogenetic Testing for Multiple Myeloma: A Comprehensive Analysis From Across the United States JCO Oncol Pract. 2020 10; 16(10):e1169-e1180. . View in PubMed
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• Lenz, Heinz-Josef
• Stram, Daniel
• Conti, David
• Wu-Williams, Anna
• Peters, Anne
• Setiawan, Veronica