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David Aaron Goldstein, MD
Associate Professor of Clinical Medicine
Rene Sr., Connie, Rene Jr., Jeffrey, and Brandon Flores Chair in Health Services Research
IRD 310 Off Campus Los Angeles
+1 323 226 6571


Dr. Goldstein received his BA in chemistry from Lafayette College and his MD from the State University of New York-Downstate Medical Center. He completed a Nephrology Fellowship at Los Angeles County + University of Southern California Medical Center.

Dr. Goldstein has been with USC for well over 40 years and has served the academic and clinical community in the following ways: Chief of the Division of Geriatric, Hospital, Palliative and General Internal Medicine; Chair, Institutional Biosafety Committee; Associate Dean for Curriculum, Chair, Clinical Practice Committee of the USC Care Medical Group.

Currently, in his capacity as Director of Primary Care for the Keck Medical Center of USC, Dr. Goldstein initiated the USC Center for Primary Care which includes faculty physicians representing General Internal Medicine, Family Medicine, Pediatrics, Obstetrics/Gynecology and Geriatrics. A wide variety of services including, but not limited to, preventive care, comprehensive and coordinated care between hospital and ambulatory settings, among specialists and sub-specialists, Women’s health, sports physicals, hospital medicine, pharmacy services, accessibility 24/7, HIV/AIDS Care and cancer screening. The Center for Primary Care has offices on the Health Sciences and University Park Campuses, as well as in Beverly Hills, Downtown Los Angeles, La Cañada and Pasadena.

As Vice Chair for Clinical Affairs, Dr. Goldstein assists in the coordination of all clinical internal medicine services for the Department of Medicine. These services include the specialty and sub-specialty disciplines that fall within the umbrella of internal medicine such as of cardiovascular medicine and endocrinology.

As Co-Director of the Pacific Center for Health Policy and Ethics, he assists in the coordination of curricular, scholarly and consultative endeavors in bioethical and moral dilemmas ranging from the bedside to societal levels. Dr. Goldstein serves as the Co-Chair of the Ethics Resource Committee of the Keck Hospital.

Dr. Goldstein, with the support from a grateful patient, has established the Gehr Family Center for Implementation Science. The Center’s mission is in part to foster research into a wide variety of healthcare innovations. The outcomes of the Gehr Center will be published in scholarly venues so they might be replicated at other healthcare institutions to improve the delivery of care nationwide.


Patient-centered medical home intervention at an internal medicine resident safety-net clinic. JAMA Intern Med. 2013 Oct 14; 173(18):1694-701. View in: PubMed

Ethical dilemmas in molecular genetics. Arch Otolaryngol Head Neck Surg. 1993 Nov; 119(11):1183-6. View in: PubMed

Baby T. Camb Q Healthc Ethics. 1992; 1(4):345-8. View in: PubMed

Hyperparathyroidism and hypotestosteronemia of acute renal failure. Am J Nephrol. 1988; 8(2):166-9. View in: PubMed

Rhabdomyolysis and pancytopenia in a young man. West J Med. 1986 May; 144(5):586-90. View in: PubMed

Role of parathyroid hormone in the glucose intolerance of chronic renal failure. J Clin Invest. 1985 Mar; 75(3):1037-44. View in: PubMed

Intact and carboxyterminal PTH do not cross the blood-cerebrospinal fluid barrier. Proc Soc Exp Biol Med. 1984 Sep; 176(4):434-7. View in: PubMed

Role of uremia, brain calcium, and parathyroid hormone on changes in electroencephalogram in chronic renal failure. Am J Physiol. 1984 May; 246(5 Pt 2):F575-9. View in: PubMed

Disturbances in the hypothalamic-pituitary-gonadal axis in male patients with acute renal failure. Am J Nephrol. 1984; 4(2):99-106. View in: PubMed

Diabetes mellitus, moderate renal insufficiency and hyperkalemia. Am J Nephrol. 1983 Jul-Aug; 3(4):233-40. View in: PubMed

Renal dysfunction in a 38-year-old man with hepatic failure. Am J Nephrol. 1983 Jan-Feb; 3(1):44-9. View in: PubMed

Recurrent acute renal failure in a patient with mixed connective tissue disease. Am J Nephrol. 1982; 2(5):282-90. View in: PubMed

Autonomic nervous system dysfunction and impotence in uremia. Am J Nephrol. 1982; 2(3):140-3. View in: PubMed

The duodenal mucosa in patients with renal failure: response to 1,25(OH)2D3. Kidney Int. 1981 Feb; 19(2):324-31. View in: PubMed

Sexual dysfunction in the male patient with uremia: a reappraisal. Kidney Int. 1981 Feb; 19(2):317-23. View in: PubMed

Vitamin D metabolites and calcium metabolism in patients with nephrotic syndrome and normal renal function. J Clin Endocrinol Metab. 1981 Jan; 52(1):116-21. View in: PubMed

Current status of the use of 1,25(OH)2D3 in the management of renal osteodystrophy. Kidney Int. 1980 Oct; 18(4):409-18. View in: PubMed

Effects of long-term therapy with calcitriol in patients with moderate renal failure. Arch Intern Med. 1980 Aug; 140(8):1030-3. View in: PubMed

The relationship between the abnormalities in electroencephalogram and blood levels of parathyroid hormone in dialysis patients. J Clin Endocrinol Metab. 1980 Jul; 51(1):130-4. View in: PubMed

Effect of an oral dose of 25-hydroxyvitamin D3 on its blood levels in patients with the nephrotic syndrome. J Clin Endocrinol Metab. 1980 Mar; 50(3):470-4. View in: PubMed

Long-term effects of 1,25(OH)2D3 on clinical and biochemical derangements of divalent ions in dialysis patients. Contrib Nephrol. 1980; 18:42-54. View in: PubMed

Effects of 6 months therapy with 1,25 (OH)2D3 on bone disease of dialysis patients. Contrib Nephrol. 1980; 18:98-104. View in: PubMed

On the pathogenesis of sexual dysfunction of the uraemic male. Proc Eur Dial Transplant Assoc. 1980; 17:139-45. View in: PubMed

Divalent ions in blood and cerebrospinal fluid: effect of hypercalcemia, hyperphosphatemia, renal failure and parathyroid hormone. Adv Exp Med Biol. 1980; 128:289-97. View in: PubMed

Parathyroid hormone, uremia, and the nervous system. Contrib Nephrol. 1980; 20:73-83. View in: PubMed

Is calcitriol [1,25(OH)2D3] harmful to renal function? JAMA. Is calcitriol [1,25(OH)2D3] harmful to renal function? JAMA. 1979 Oct 26; 242(17):1875-6. View in: PubMed

Relationship between the concentrations of calcium and phosphorus in blood and cerebrospinal fluid. J Clin Endocrinol Metab. 1979 Jul; 49(1):58-62. View in: PubMed

Reversal of skeletal resistance to parathyroid hormone in uremia by vitamin D metabolites: evidence for the requirement of 1,25(OH)2D3 and 24,25(OH)2D3. J Lab Clin Med. 1979 Jul; 94(1):152-7. View in: PubMed

The search for uremic toxin(s) "X" "X" = PTH. Clin Nephrol. 1979 Apr; 11(4):181-9. View in: PubMed

Osteomalacia and hyperparathyroid bone disease in patients with nephrotic syndrome. J Clin Invest. 1979 Mar; 63(3):494-500. View in: PubMed

Early dialysis in diabetic patients with chronic renal failure. Nephron. 1979; 23(1):2-5. View in: PubMed

Resolution of muscle calcification in rhabdomyolysis and acute renal failure. Ann Intern Med. 1978 Dec; 89(6):928-30. View in: PubMed

On the genesis of the clinical manifestations of hypercalcemic disorders. West J Med. 1978 Oct; 129(4):333-5. View in: PubMed

Calcium metabolism in patients with nephrotic syndrome. A state with vitamin D deficiency. Am J Clin Nutr. 1978 Sep; 31(9):1572-80. View in: PubMed

Effect of parathyroid hormone and uremia on peripheral nerve calcium and motor nerve conduction velocity. J Clin Invest. 1978 Jul; 62(1):88-93. View in: PubMed

Role of parathyroid hormone in uremic toxicity. Kidney Int Suppl. 1978 Jun; (8):S39-42. View in: PubMed

Diabetic nephropathy: clinical course and effect of hemodialysis. Nephron. 1978; 20(5):286-96. View in: PubMed

Blood levels of 25-hydroxyvitamin D in nephrotic syndrome. Studies in 26 patients. Ann Intern Med. 1977 Dec; 87(6):664-7. View in: PubMed

Impotence in patients with uremia: a possible role for parathyroid hormone. Nephron. 1977; 19(6):305-10. View in: PubMed

Acute renal failure in patients with acute pancreatitis. Arch Intern Med. 1976 Dec; 136(12):1363-5. View in: PubMed

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