Faculty

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David John Van Den Berg, PhD
Associate Professor of Clinical Preventive Medicine
Director, USC Epigenome Center For Data Production
Preventive Medicine
NRT G517 1450 Biggy Street Health Sciences Campus Los Angeles
+1 323 442 4341

Publications

An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression. Hum Mol Genet. 2016 Jul 11. View in: PubMed

Genome-wide association study of colorectal cancer in Hispanics. Carcinogenesis. 2016 Jun; 37(6):547-56. View in: PubMed

No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing. J Med Genet. 2016 May; 53(5):298-309. View in: PubMed

Cannabis use and transition to psychosis in individuals at ultra-high risk: review and meta-analysis. Psychol Med. 2016 Mar; 46(4):673-81. View in: PubMed

Corrigendum: Common variants at 19p13 are associated with susceptibility to ovarian cancer. Nat Genet. 2015 Dec 29; 48(1):101. View in: PubMed

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types. J Natl Cancer Inst. 2015 Dec; 107(12). View in: PubMed

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med. 2015 Jun 25; 372(26):2481-98. View in: PubMed

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31. 2. Hum Mol Genet. 2015 May 15; 24(10):2966-84. View in: PubMed

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. Nat Genet. 2015 Apr; 47(4):373-80. View in: PubMed

Fine-Scale Mapping of the 5q11. 2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1. Am J Hum Genet. 2015 Jan 8; 96(1):5-20. View in: PubMed

Methodological Considerations in Estimation of Phenotype Heritability Using Genome-Wide SNP Data, Illustrated by an Analysis of the Heritability of Height in a Large Sample of African Ancestry Adults. PLoS One. 2015; 10(6):e0131106. View in: PubMed

Corrigendum: Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nat Commun. 2015; 6:8739. View in: PubMed

Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nat Commun. 2015; 6:7138. View in: PubMed

15q12 Variants, Sputum Gene Promoter Hypermethylation, and Lung Cancer Risk: A GWAS in Smokers. J Natl Cancer Inst. 2015; 107(5). View in: PubMed

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk. Hum Mol Genet. 2015 Jan 1; 24(1):285-98. View in: PubMed

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15. 33. Hum Mol Genet. 2014 Dec 15; 23(24):6616-33. View in: PubMed

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium. Hum Mol Genet. 2014 Nov 15; 23(22):6096-111. View in: PubMed

The 19q12 Bladder Cancer GWAS Signal: Association with Cyclin E Function and Aggressive Disease. Cancer Res. 2014 Oct 15; 74(20):5808-18. View in: PubMed

Genome-wide interaction studies reveal sex-specific asthma risk alleles. Hum Mol Genet. 2014 Oct 1; 23(19):5251-9. View in: PubMed

Genetic risk factors for orofacial clefts in Central Africans and Southeast Asians. Am J Med Genet A. 2014 Oct; 164(10):2572-80. View in: PubMed

Genome-wide interaction study of smoking and bladder cancer risk. Carcinogenesis. 2014 Aug; 35(8):1737-44. View in: PubMed

Antiretroviral therapy modifies the genetic effect of known type 2 diabetes-associated risk variants in HIV-infected women. AIDS. 2014 Jul 31; 28(12):1815-23. View in: PubMed

Comprehensive analyses of DNA repair pathways, smoking and bladder cancer risk in Los Angeles and Shanghai. Int J Cancer. 2014 Jul 15; 135(2):335-47. View in: PubMed

Breast Cancer Susceptibility Variants and Mammographic Density Phenotypes in Norwegian Postmenopausal Women. Cancer Epidemiol Biomarkers Prev. 2014 Jul 7. View in: PubMed

Variation in NF-?B Signaling Pathways and Survival in Invasive Epithelial Ovarian Cancer. Cancer Epidemiol Biomarkers Prev. 2014 Jul; 23(7):1421-7. View in: PubMed

Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome. Cancer Immunol Res. 2014 Apr; 2(4):332-40. View in: PubMed

Genome-wide association study identifies multiple loci associated with bladder cancer risk. Hum Mol Genet. 2014 Mar 1; 23(5):1387-98. View in: PubMed

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium. Br J Cancer. 2014 Feb 18; 110(4):1088-100. View in: PubMed

Risk of Ovarian Cancer and the NF-?B Pathway: Genetic Association with IL1A and TNFSF10. Cancer Res. 2014 Feb 1; 74(3):852-61. View in: PubMed

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study. Breast Cancer Res. 2014; 16(3):R51. View in: PubMed

Hormone metabolism pathway genes and mammographic density change after quitting estrogen and progestin combined hormone therapy in the California Teachers Study. Breast Cancer Res. 2014; 16(6):477. View in: PubMed

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nat Commun. 2014; 4:4999. View in: PubMed

Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. Nat Commun. 2014; 5:4613. View in: PubMed

A meta-analysis of Hodgkin lymphoma reveals 19p13. 3 TCF3 as a novel susceptibility locus. Nat Commun. 2014; 5:3856. View in: PubMed

Exome-wide association study of endometrial cancer in a multiethnic population. PLoS One. 2014; 9(5):e97045. View in: PubMed

Fine-Scale Mapping of the FGFR2 Breast Cancer Risk Locus: Putative Functional Variants Differentially Bind FOXA1 and E2F1. Am J Hum Genet. 2013 Dec 5; 93(6):1046-60. View in: PubMed

Native american ancestry affects the risk for gene methylation in the lungs of Hispanic smokers from new Mexico. Am J Respir Crit Care Med. 2013 Nov 1; 188(9):1110-6. View in: PubMed

Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23. Hum Mol Genet. 2013 Jul 1; 22(13):2748-53. View in: PubMed

Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls. Hum Mol Genet. 2013 Jun 15; 22(12):2539-50. View in: PubMed

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet. 2013 Jun; 45(6):690-6. View in: PubMed

Hormone metabolism genes and mammographic density in Singapore Chinese women. Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):984-6. View in: PubMed

Elevated 4-aminobiphenyl and 2,6-dimethylaniline hemoglobin adducts and increased risk of bladder cancer among lifelong nonsmokers--The Shanghai Bladder Cancer Study. Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):937-45. View in: PubMed

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. Am J Hum Genet. 2013 Apr 4; 92(4):489-503. View in: PubMed

Low-level processing of Illumina Infinium DNA Methylation BeadArrays. Nucleic Acids Res. 2013 Apr; 41(7):e90. View in: PubMed

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat Genet. 2013 Apr; 45(4):362-70, 370e1-2. View in: PubMed

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet. 2013 Apr; 45(4):371-84, 384e1-2. View in: PubMed

Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet. 2013 Apr; 45(4):353-61, 361e1-2. View in: PubMed

Large chromosome deletions, duplications, and gene conversion events accumulate with age in normal human colon crypts. Aging Cell. 2013 Apr; 12(2):269-79. View in: PubMed

Genetic variation in transforming growth factor beta 1 and mammographic density in Singapore Chinese women. Cancer Res. 2013 Mar 15; 73(6):1876-82. View in: PubMed

Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population. PLoS Genet. 2013 Mar; 9(3):e1003419. View in: PubMed

A genome-wide association study of breast cancer in women of African ancestry. Hum Genet. 2013 Jan; 132(1):39-48. View in: PubMed

Genetic polymorphisms of epidermal growth factor in relation to risk of hepatocellular carcinoma: two case-control studies. BMC Gastroenterol. 2013; 13:32. View in: PubMed

Reproducibility and reliability of SNP analysis using human cellular DNA at or near nanogram levels. BMC Res Notes. 2013; 6:515. View in: PubMed

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer. Nat Commun. 2013; 4:1628. View in: PubMed

A genome-wide scan for breast cancer risk haplotypes among African American women. PLoS One. 2013; 8(2):e57298. View in: PubMed

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet. 2012 Dec 15; 21(24):5373-84. View in: PubMed

Underlying genetic structure impacts the association between CYP2B6 polymorphisms and response to efavirenz and nevirapine. AIDS. 2012 Oct 23; 26(16):2097-106. View in: PubMed

Variations in sex hormone metabolism genes, postmenopausal hormone therapy and risk of endometrial cancer. Int J Cancer. 2012 Apr 1; 130(7):1629-38. View in: PubMed

Genetic variation in peroxisome proliferator-activated receptor gamma, soy, and mammographic density in singapore chinese women. Cancer Epidemiol Biomarkers Prev. 2012 Apr; 21(4):635-44. View in: PubMed

Progestogen levels, progesterone receptor gene polymorphisms, and mammographic density changes: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density Study. Menopause. 2012 Mar; 19(3):302-10. View in: PubMed

Genome-scale analysis of aberrant DNA methylation in colorectal cancer. Genome Res. 2012 Feb; 22(2):271-82. View in: PubMed

Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study. Cancer Res. 2012 Feb 1; 72(3):707-15. View in: PubMed

A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21. 32. Blood. 2012 Jan 12; 119(2):469-75. View in: PubMed

Polymorphisms in hormone metabolism and growth factor genes and mammographic density in Norwegian postmenopausal hormone therapy users and non-users. Breast Cancer Res. 2012; 14(5):R135. View in: PubMed

Combined effects of MDM2 SNP309 and TP53 R72P polymorphisms, and soy isoflavones on breast cancer risk among Chinese women in Singapore. Breast Cancer Res Treat. 2011 Dec; 130(3):1011-9. View in: PubMed

Characteristics of Triple-Negative Breast Cancer in Patients With a BRCA1 Mutation: Results From a Population-Based Study of Young Women. J Clin Oncol. 2011 Nov 20; 29(33):4373-80. View in: PubMed

Glutathione S-transferase (GST) gene polymorphisms, cigarette smoking and colorectal cancer risk among Chinese in Singapore. Carcinogenesis. 2011 Oct; 32(10):1507-11. View in: PubMed

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet. 2011 Sep; 43(9):887-92. View in: PubMed

Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk. Hum Mol Genet. 2011 Jun 1; 20(11):2263-72. View in: PubMed

Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nat Genet. 2011 Jun; 43(6):570-3. View in: PubMed

Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer. Int J Cancer. 2011 May 1; 128(9):2063-74. View in: PubMed

Association of the calcyon neuron-specific vesicular protein gene (CALY) with adolescent smoking initiation in China and California. Am J Epidemiol. 2011 May 1; 173(9):1039-48. View in: PubMed

Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study. Carcinogenesis. 2011 Feb; 32(2):197-202. View in: PubMed

The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort. Breast Cancer Res. 2011; 13(2):R37. View in: PubMed

Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains. Nat Genet. 2011; 44(1):40-6. View in: PubMed

Progesterone receptor gene polymorphisms and risk of endometriosis: results from an international collaborative effort. Fertil Steril. 2011 Jan; 95(1):40-5. View in: PubMed

Risk of urinary bladder cancer is associated with 8q24 variant rs9642880[T] in multiple racial/ethnic groups: results from the Los Angeles-Shanghai case-control study. Cancer Epidemiol Biomarkers Prev. 2010 Dec; 19(12):3150-6. View in: PubMed

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet. 2010 Nov; 42(11):978-84. View in: PubMed

Common variants at 19p13 are associated with susceptibility to ovarian cancer. Nat Genet. 2010 Oct; 42(10):880-4. View in: PubMed

Genetic variation in the progesterone receptor gene and risk of endometrial cancer: a haplotype-based approach. Carcinogenesis. 2010 Aug; 31(8):1392-9. View in: PubMed

Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev. 2010 Jul; 19(7):1822-30. View in: PubMed

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell. 2010 May 18; 17(5):510-22. View in: PubMed

Role of inducible nitric oxide synthase in asthma risk and lung function growth during adolescence. Thorax. 2010 Feb; 65(2):139-45. View in: PubMed

Polymorphism in the GALNT1 gene and epithelial ovarian cancer in non-Hispanic white women: the Ovarian Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev. 2010 Feb; 19(2):600-4. View in: PubMed

Genetic Association Between the COMT Genotype and Urinary Levels of Tea Polyphenols and Their Metabolites among Daily Green Tea Drinkers. Int J Mol Epidemiol Genet. 2010; 1(2):114-123. View in: PubMed

ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study. Cancer Epidemiol Biomarkers Prev. 2010 Jan; 19(1):245-50. View in: PubMed

Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms and gastric cancer risk: a prospective study of men in Shanghai, China. Int J Cancer. 2009 Dec 1; 125(11):2652-9. View in: PubMed

Sequence variant on 3q28 and urinary bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study. Cancer Epidemiol Biomarkers Prev. 2009 Nov; 18(11):3057-61. View in: PubMed

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22. 2. Nat Genet. 2009 Sep; 41(9):996-1000. View in: PubMed

Dopamine genes and nicotine dependence in treatment-seeking and community smokers. Neuropsychopharmacology. 2009 Sep; 34(10):2252-64. View in: PubMed

Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study. Hum Mol Genet. 2009 Jun 15; 18(12):2297-304. View in: PubMed

Polymorphisms in the FGF2 gene and risk of serous ovarian cancer: results from the ovarian cancer association consortium. Twin Res Hum Genet. 2009 Jun; 12(3):269-75. View in: PubMed

Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung function. Am J Respir Crit Care Med. 2009 Apr 1; 179(7):601-7. View in: PubMed

Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer. Br J Cancer. 2009 Mar 24; 100(6):993-1001. View in: PubMed

Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer. Cancer Res. 2009 Mar 15; 69(6):2349-57. View in: PubMed

Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium. Br J Cancer. 2009 Jan 27; 100(2):412-20. View in: PubMed

Effect of reproductive factors and oral contraceptives on breast cancer risk in BRCA1/2 mutation carriers and noncarriers: results from a population-based study. Cancer Epidemiol Biomarkers Prev. 2008 Nov; 17(11):3170-8. View in: PubMed

Green tea intake, MTHFR/TYMS genotype and breast cancer risk: the Singapore Chinese Health Study. Carcinogenesis. 2008 Oct; 29(10):1967-72. View in: PubMed

Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. Hum Mol Genet. 2008 Sep 15; 17(18):2834-48. View in: PubMed

No association between the SRD5A2 gene A49T missense variant and prostate cancer risk: lessons learned. Hum Mol Genet. 2008 Aug 15; 17(16):2456-61. View in: PubMed

Association between common genetic variation in Cockayne syndrome A and B genes and nucleotide excision repair capacity among smokers. Cancer Epidemiol Biomarkers Prev. 2008 Aug; 17(8):2062-9. View in: PubMed

Insulin-like growth factor-1 promoter polymorphisms and colorectal cancer: a functional genomics approach. Gut. 2008 Aug; 57(8):1090-6. View in: PubMed

Consortium analysis of 7 candidate SNPs for ovarian cancer. Int J Cancer. 2008 Jul 15; 123(2):380-8. View in: PubMed

Haplotypes of DNMT1 and DNMT3B are associated with mutagen sensitivity induced by benzo[a]pyrene diol epoxide among smokers. Carcinogenesis. 2008 Jul; 29(7):1380-5. View in: PubMed

Urinary total isothiocyanates and colorectal cancer: a prospective study of men in Shanghai, China. Cancer Epidemiol Biomarkers Prev. 2008 Jun; 17(6):1354-9. View in: PubMed

Improved piercing of microneedle arrays in dermatomed human skin by an impact insertion method. J Control Release. 2008 May 22; 128(1):80-8. View in: PubMed

Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation. Cancer Res. 2008 Apr 15; 68(8):3049-56. View in: PubMed

Interleukin-2, interleukin-12, and interferon-gamma levels and risk of young adult Hodgkin lymphoma. Blood. 2008 Apr 1; 111(7):3377-82. View in: PubMed

Comprehensive association testing of common genetic variation in DNA repair pathway genes in relationship with breast cancer risk in multiple populations. Hum Mol Genet. 2008 Mar 15; 17(6):825-34. View in: PubMed

Comprehensive evaluation of ESR2 variation and ovarian cancer risk. Cancer Epidemiol Biomarkers Prev. 2008 Feb; 17(2):393-6. View in: PubMed

The role of established breast cancer susceptibility loci in mammographic density in young women. Cancer Epidemiol Biomarkers Prev. 2008 Jan; 17(1):258-60. View in: PubMed

Snagger: a user-friendly program for incorporating additional information for tagSNP selection. BMC Bioinformatics. 2008; 9:174. View in: PubMed

Evaluation of unclassified variants in the breast cancer susceptibility genes BRCA1 and BRCA2 using five methods: results from a population-based study of young breast cancer patients. Breast Cancer Res. 2008; 10(1):R19. View in: PubMed

Germ line variation at 8q24 and endometrial cancer risk. Cancer Epidemiol Biomarkers Prev. 2007 Oct; 16(10):2166-8. View in: PubMed

Genetic polymorphisms in the methylenetetrahydrofolate reductase and thymidylate synthase genes and risk of hepatocellular carcinoma. Hepatology. 2007 Sep; 46(3):749-58. View in: PubMed

A systematic assessment of common genetic variation in CYP11A and risk of breast cancer. Cancer Res. 2006 Dec 15; 66(24):12019-25. View in: PubMed

The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in the Singapore Chinese Health Study. Carcinogenesis. 2006 Dec; 27(12):2475-82. View in: PubMed

Interleukin-6-related genotypes, body mass index, and risk of multiple myeloma and plasmacytoma. Cancer Epidemiol Biomarkers Prev. 2006 Nov; 15(11):2285-91. View in: PubMed

Peroxisome proliferator-activated receptor (PPAR) gamma gene polymorphisms and colorectal cancer risk among Chinese in Singapore. Carcinogenesis. 2006 Sep; 27(9):1797-802. View in: PubMed

The effect of cyclin D1 (CCND1) G870A-polymorphism on breast cancer risk is modified by oxidative stress among Chinese women in Singapore. Carcinogenesis. 2005 Aug; 26(8):1457-64. View in: PubMed

Sun exposure, vitamin D receptor gene polymorphisms, and risk of advanced prostate cancer. Cancer Res. 2005 Jun 15; 65(12):5470-9. View in: PubMed

Tea and circulating estrogen levels in postmenopausal Chinese women in Singapore. Carcinogenesis. 2005 May; 26(5):976-80. View in: PubMed

Polymorphisms in angiotensin II type 1 receptor and angiotensin I-converting enzyme genes and breast cancer risk among Chinese women in Singapore. Carcinogenesis. 2005 Feb; 26(2):459-64. View in: PubMed

A new single nucleotide polymorphism in the insulin-like growth factor I regulatory region associates with colorectal cancer risk in singapore chinese. Cancer Epidemiol Biomarkers Prev. 2005 Jan; 14(1):144-51. View in: PubMed

Polymorphisms in genes involved in estrogen and progesterone metabolism and mammographic density changes in women randomized to postmenopausal hormone therapy: results from a pilot study. Breast Cancer Res. 2005; 7(3):R336-44. View in: PubMed

Marine n-3 fatty acid intake, glutathione S-transferase polymorphisms and breast cancer risk in post-menopausal Chinese women in Singapore. Carcinogenesis. 2004 Nov; 25(11):2143-7. View in: PubMed

Interaction between cyclooxygenase-2 gene polymorphism and dietary n-6 polyunsaturated fatty acids on colon cancer risk: the Singapore Chinese Health Study. Br J Cancer. 2004 May 4; 90(9):1760-4. View in: PubMed

T29C polymorphism in the transforming growth factor beta1 gene and postmenopausal breast cancer risk: the Multiethnic Cohort Study. Cancer Epidemiol Biomarkers Prev. 2004 Mar; 13(3):412-5. View in: PubMed

Tea intake, COMT genotype, and breast cancer in Asian-American women. Cancer Res. 2003 Nov 1; 63(21):7526-9. View in: PubMed

The relationship between twenty missense ATM variants and breast cancer risk: the Multiethnic Cohort. Cancer Epidemiol Biomarkers Prev. 2003 Aug; 12(8):733-8. View in: PubMed

HSD17B1 and CYP17 polymorphisms and breast cancer risk among Chinese women in Singapore. Int J Cancer. 2003 Apr 20; 104(4):450-7. View in: PubMed

Angiotensin I-converting enzyme (ACE) gene polymorphism and breast cancer risk among Chinese women in Singapore. Cancer Res. 2003 Feb 1; 63(3):573-8. View in: PubMed

Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study. Carcinogenesis. 2002 Dec; 23(12):2055-61. View in: PubMed

A genome screen of families with multiple cases of prostate cancer: evidence of genetic heterogeneity. Am J Hum Genet. 2001 Jul; 69(1):148-58. View in: PubMed

In vitro and in vivo investigations on fluoroquinolones; effects of the P-glycoprotein efflux transporter on brain distribution of sparfloxacin. Eur J Pharm Sci. 2000 Dec; 12(2):85-93. View in: PubMed

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier. J Clin Invest. 2000 Feb; 105(3):279-85. View in: PubMed

Role of members of the Wnt gene family in human hematopoiesis. Blood. 1998 Nov 1; 92(9):3189-202. View in: PubMed

The Smad5 gene is involved in the intracellular signaling pathways that mediate the inhibitory effects of transforming growth factor-beta on human hematopoiesis. Blood. 1998 Mar 15; 91(6):1917-23. View in: PubMed

Monohydroxyethylrutoside, a dose-dependent cardioprotective agent, does not affect the antitumor activity of doxorubicin. Clin Cancer Res. 1997 Oct; 3(10):1747-54. View in: PubMed

Mobilization and transplantation of Philadelphia-negative peripheral-blood progenitor cells early in chronic myelogenous leukemia. J Clin Oncol. 1997 Apr; 15(4):1575-82. View in: PubMed

Leukemic burden in subpopulations of CD34+ cells isolated from the mobilized peripheral blood of alpha-interferon-resistant or -intolerant patients with chronic myeloid leukemia. Blood. 1996 May 15; 87(10):4348-57. View in: PubMed

Roberts syndrome: a review of 100 cases and a new rating system for severity. Am J Med Genet. 1993 Nov 15; 47(7):1104-23. View in: PubMed

Sensitivity of Roberts syndrome cells to gamma radiation, mitomycin C, and protein synthesis inhibitors. Somat Cell Mol Genet. 1993 Jul; 19(4):377-92. View in: PubMed

Structure of the gene for Xenopus transcription factor TFIIIA. Nucleic Acids Res. 1986 Mar 11; 14(5):2187-200. View in: PubMed

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