Faculty

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Edward Lawrence Avol, MS
Professor of Clinical Preventive Medicine
Environmental Health
SSB 230C 2001 N. Soto Street Health Sciences Campus Los Angeles
+1 323 442 1090

Overview

Ed Avol is Professor of Clinical Preventive Medicine, with expertise in exposure assessment and acute/chronic respiratory and cardiovascular effects of airborne pollutants in populations at risk (including children, athletes, and subjects with compromised lung function). He was the Deputy Director of the Children's Health Study and is a key investigator in multiple ongoing investigations of the effects of environmental exposures on human health. He is the co-Director of the Exposure Assessment and GIS Facility Core in the NIEHS-supported Southern California Environmental Health Sciences Center, co-Director of the Exposure Assessment and Modeling Core in the NIEHS/EPA-supported Children's Environmental Health Center, and is the principal investigator on several NIH and regionally funded studies to assess the association of air pollution with children?s respiratory and cardiovascular health. Professor Avol is also actively involved in the centers’ community outreach efforts, particularly with regard to the health and air quality impacts of the Los Angeles/Long Beach Port expansions.

Publications

Tam E, Miike R, Labrenz S, Sutton AJ, Elias T, Davis J, Chen YL, Tantisira K, Dockery D, Avol E. Volcanic air pollution over the Island of Hawai'i: Emissions, dispersal, and composition. Association with respiratory symptoms and lung function in Hawai'i Island school children. Environ Int. 2016 Jul-Aug; 92-93:543-52. View in: PubMed

Spalt EW, Curl CL, Allen RW, Cohen M, Adar SD, Stukovsky KH, Avol E, Castro-Diehl C, Nunn C, Mancera-Cuevas K, Kaufman JD. Time-location patterns of a diverse population of older adults: the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air). J Expo Sci Environ Epidemiol. 2016 Jun; 26(4):349-55. View in: PubMed

Spalt EW, Curl CL, Allen RW, Cohen M, Adar SD, Stukovsky KH, Avol E, Castro-Diehl C, Nunn C, Mancera-Cuevas K, Kaufman JD. Time-location patterns of a diverse population of older adults: the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air). J Expo Sci Environ Epidemiol. 2016 Jun; 26(4):436. View in: PubMed

Berhane K, Chang CC, McConnell R, Gauderman WJ, Avol E, Rapapport E, Urman R, Lurmann F, Gilliland F. Association of Changes in Air Quality With Bronchitic Symptoms in Children in California, 1993-2012. JAMA. 2016 Apr 12; 315(14):1491-501. View in: PubMed

Breton CV, Mack WJ, Yao J, Berhane K, Amadeus M, Lurmann F, Gilliland F, McConnell R, Hodis HN, Künzli N, Avol E. Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults. PLoS One. 2016; 11(3):e0150825. View in: PubMed

Gauderman WJ, Urman R, Avol E, Berhane K, McConnell R, Rappaport E, Chang R, Lurmann F, Gilliland F. Association of improved air quality with lung development in children. N Engl J Med. 2015 Mar 5; 372(10):905-13. View in: PubMed

Lurmann F, Avol E, Gilliland F. Emissions reduction policies and recent trends in Southern California's ambient air quality. J Air Waste Manag Assoc. 2015 Mar; 65(3):324-35. View in: PubMed

Sussman S, Ames SL, Avol E. Could environmental exposures facilitate the incidence of addictive behaviors? Eval Health Prof. 2015 Mar; 38(1):53-8. View in: PubMed

Urman R, McConnell R, Islam T, Avol EL, Lurmann FW, Vora H, Linn WS, Rappaport EB, Gilliland FD, Gauderman WJ. Associations of children's lung function with ambient air pollution: joint effects of regional and near-roadway pollutants. Thorax. 2014 Jun; 69(6):540-7. View in: PubMed

Breton CV, Park C, Siegmund K, Gauderman WJ, Whitfield-Maxwell L, Hodis HN, Avol E, Gilliland FD. NOS1 Methylation and Carotid Artery Intima-Media Thickness in Children. Circ Cardiovasc Genet. 2014 Apr 1; 7(2):116-22. View in: PubMed

Breton CV, Yin F, Wang X, Avol E, Gilliland FD, Araujo JA. HDL anti-oxidant function associates with LDL level in young adults. Atherosclerosis. 2014 Jan; 232(1):165-70. View in: PubMed

Breton CV, Wang X, Mack WJ, Berhane K, Lopez M, Islam TS, Feng M, Lurmann F, McConnell R, Hodis HN, Künzli N, Avol E. Response to letter regarding article, “Childhood air pollutant exposure and carotid artery intima–media thickness in young adults”. Circulation. 2013 Jun 4; 127(22):e659. View in: PubMed

Dratva J, Breton CV, Hodis HN, Mack WJ, Salam MT, Zemp E, Gilliland F, Kuenzli N, Avol E. Birth weight and carotid artery intima-media thickness. J Pediatr. 2013 May; 162(5):906-11. e1-2. View in: PubMed

Breton CV, Wang X, Mack WJ, Berhane K, Lopez M, Islam TS, Feng M, Lurmann F, McConnell R, Hodis HN, Künzli N, Avol E. Childhood air pollutant exposure and carotid artery intima-media thickness in young adults. Circulation. 2012 Sep 25; 126(13):1614-20. View in: PubMed

Allen RW, Adar SD, Avol E, Cohen M, Curl CL, Larson T, Liu LJ, Sheppard L, Kaufman JD. Modeling the residential infiltration of outdoor PM(2. 5) in the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air). Environ Health Perspect. 2012 Jun; 120(6):824-30. View in: PubMed

Franklin M, Vora H, Avol E, McConnell R, Lurmann F, Liu F, Penfold B, Berhane K, Gilliland F, Gauderman WJ. Predictors of intra-community variation in air quality. J Expo Sci Environ Epidemiol. 2012 Mar; 22(2):135-47. View in: PubMed

Eckel SP, Berhane K, Salam MT, Rappaport EB, Linn WS, Bastain TM, Zhang Y, Lurmann F, Avol EL, Gilliland FD. Residential traffic-related pollution exposures and exhaled nitric oxide in the children's health study. Environ Health Perspect. 2011 Oct; 119(10):1472-7. View in: PubMed

Islam T, Urman R, Gauderman WJ, Milam J, Lurmann F, Shankardass K, Avol E, Gilliland F, McConnell R. Parental stress increases the detrimental effect of traffic exposure on children's lung function. Am J Respir Crit Care Med. 2011 Oct 1; 184(7):822-7. View in: PubMed

Breton CV, Wang X, Mack WJ, Berhane K, Lopez M, Islam TS, Feng M, Hodis HN, Künzli N, Avol E. Carotid artery intima-media thickness in college students: race/ethnicity matters. Atherosclerosis. 2011 Aug; 217(2):441-6. View in: PubMed

McConnell R, Islam T, Shankardass K, Jerrett M, Lurmann F, Gilliland F, Gauderman J, Avol E, Künzli N, Yao L, Peters J, Berhane K. Childhood incident asthma and traffic-related air pollution at home and school. Environ Health Perspect. 2010 Jul; 118(7):1021-6. View in: PubMed

Perez L, Künzli N, Avol E, Hricko AM, Lurmann F, Nicholas E, Gilliland F, Peters J, McConnell R. Global goods movement and the local burden of childhood asthma in southern California. Am J Public Health. 2009 Nov; 99 Suppl 3:S622-8. View in: PubMed

Linn WS, Berhane KT, Rappaport EB, Bastain TM, Avol EL, Gilliland FD. Relationships of online exhaled, offline exhaled, and ambient nitric oxide in an epidemiologic survey of schoolchildren. J Expo Sci Environ Epidemiol. 2009 Nov; 19(7):674-81. View in: PubMed

Cohen MA, Adar SD, Allen RW, Avol E, Curl CL, Gould T, Hardie D, Ho A, Kinney P, Larson TV, Sampson P, Sheppard L, Stukovsky KD, Swan SS, Liu LJ, Kaufman JD. Approach to estimating participant pollutant exposures in the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air). Environ Sci Technol. 2009 Jul 1; 43(13):4687-93. View in: PubMed

Mirabelli MC, Künzli N, Avol E, Gilliland FD, Gauderman WJ, McConnell R, Peters JM. Respiratory symptoms following wildfire smoke exposure: airway size as a susceptibility factor. Epidemiology. 2009 May; 20(3):451-9. View in: PubMed

Wenten M, Li YF, Lin PC, Gauderman WJ, Berhane K, Avol E, Gilliland FD. In utero smoke exposure, glutathione S-transferase P1 haplotypes, and respiratory illness-related absence among schoolchildren. Pediatrics. 2009 May; 123(5):1344-51. View in: PubMed

Linn WS, Rappaport EB, Berhane KT, Bastain TM, Avol EL, Gilliland FD. Exhaled nitric oxide in a population-based study of southern California schoolchildren. Respir Res. 2009; 10:28. View in: PubMed

Jerrett M, Shankardass K, Berhane K, Gauderman WJ, Künzli N, Avol E, Gilliland F, Lurmann F, Molitor JN, Molitor JT, Thomas DC, Peters J, McConnell R. Traffic-related air pollution and asthma onset in children: a prospective cohort study with individual exposure measurement. Environ Health Perspect. 2008 Oct; 116(10):1433-8. View in: PubMed

Cozen W, Avol E, Diaz-Sanchez D, McConnell R, Gauderman WJ, Cockburn MG, Zadnick J, Jyrala M, Mack TM. Use of an electrostatic dust cloth for self-administered home allergen collection. Twin Res Hum Genet. 2008 Apr; 11(2):150-5. View in: PubMed

Li YF, Gauderman WJ, Conti DV, Lin PC, Avol E, Gilliland FD. Glutathione S-transferase P1, maternal smoking, and asthma in children: a haplotype-based analysis. Environ Health Perspect. 2008 Mar; 116(3):409-15. View in: PubMed

Islam T, McConnell R, Gauderman WJ, Avol E, Peters JM, Gilliland FD. Ozone, oxidant defense genes, and risk of asthma during adolescence. Am J Respir Crit Care Med. 2008 Feb 15; 177(4):388-95. View in: PubMed

Salam MT, Lin PC, Avol EL, Gauderman WJ, Gilliland FD. Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma. Thorax. 2007 Dec; 62(12):1050-7. View in: PubMed

Islam T, Gauderman WJ, Berhane K, McConnell R, Avol E, Peters JM, Gilliland FD. Relationship between air pollution, lung function and asthma in adolescents. Thorax. 2007 Nov; 62(11):957-63. View in: PubMed

Gauderman WJ, Vora H, McConnell R, Berhane K, Gilliland F, Thomas D, Lurmann F, Avol E, Kunzli N, Jerrett M, Peters J. Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study. Lancet. 2007 Feb 17; 369(9561):571-7. View in: PubMed

McConnell R, Berhane K, Molitor J, Gilliland F, Künzli N, Thorne PS, Thomas D, Gauderman WJ, Avol E, Lurmann F, Rappaport E, Jerrett M, Peters JM. Dog ownership enhances symptomatic responses to air pollution in children with asthma. Environ Health Perspect. 2006 Dec; 114(12):1910-5. View in: PubMed

Künzli N, Avol E, Wu J, Gauderman WJ, Rappaport E, Millstein J, Bennion J, McConnell R, Gilliland FD, Berhane K, Lurmann F, Winer A, Peters JM. Health effects of the 2003 Southern California wildfires on children. Am J Respir Crit Care Med. 2006 Dec 1; 174(11):1221-8. View in: PubMed

Gilliland FD, Islam T, Berhane K, Gauderman WJ, McConnell R, Avol E, Peters JM. Regular smoking and asthma incidence in adolescents. Am J Respir Crit Care Med. 2006 Nov 15; 174(10):1094-100. View in: PubMed

McConnell R, Berhane K, Yao L, Lurmann FW, Avol E, Peters JM. Predicting residential ozone deficits from nearby traffic. Sci Total Environ. 2006 Jun 15; 363(1-3):166-74. View in: PubMed

McConnell R, Berhane K, Yao L, Jerrett M, Lurmann F, Gilliland F, Künzli N, Gauderman J, Avol E, Thomas D, Peters J. Traffic, susceptibility, and childhood asthma. Environ Health Perspect. 2006 May; 114(5):766-72. View in: PubMed

Li YF, Gauderman WJ, Avol E, Dubeau L, Gilliland FD. Associations of tumor necrosis factor G-308A with childhood asthma and wheezing. Am J Respir Crit Care Med. 2006 May 1; 173(9):970-6. View in: PubMed

Salam MT, Margolis HG, McConnell R, McGregor JA, Avol EL, Gilliland FD. Mode of delivery is associated with asthma and allergy occurrences in children. Ann Epidemiol. 2006 May; 16(5):341-6. View in: PubMed

Wenten M, Berhane K, Rappaport EB, Avol E, Tsai WW, Gauderman WJ, McConnell R, Dubeau L, Gilliland FD. TNF-308 modifies the effect of second-hand smoke on respiratory illness-related school absences. Am J Respir Crit Care Med. 2005 Dec 15; 172(12):1563-8. View in: PubMed

Gauderman WJ, Avol E, Lurmann F, Kuenzli N, Gilliland F, Peters J, McConnell R. Childhood asthma and exposure to traffic and nitrogen dioxide. Epidemiology. 2005 Nov; 16(6):737-43. View in: PubMed

Gilliland F, Avol E, Kinney P, Jerrett M, Dvonch T, Lurmann F, Buckley T, Breysse P, Keeler G, de Villiers T, McConnell R. Air pollution exposure assessment for epidemiologic studies of pregnant women and children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environ Health Perspect. 2005 Oct; 113(10):1447-54. View in: PubMed

Li YF, Tsao YH, Gauderman WJ, Conti DV, Avol E, Dubeau L, Gilliland FD. Intercellular adhesion molecule-1 and childhood asthma. Hum Genet. 2005 Sep; 117(5):476-84. View in: PubMed

Thorne PS, Metwali N, Avol E, McConnell RS. Surface sampling for endotoxin assessment using electrostatic wiping cloths. Ann Occup Hyg. 2005 Jul; 49(5):401-6. View in: PubMed

Millstein J, Gilliland F, Berhane K, Gauderman WJ, McConnell R, Avol E, Rappaport EB, Peters JM. Effects of ambient air pollutants on asthma medication use and wheezing among fourth-grade school children from 12 Southern California communities enrolled in The Children's Health Study. Arch Environ Health. 2004 Oct; 59(10):505-14. View in: PubMed

Gauderman WJ, Avol E, Gilliland F, Vora H, Thomas D, Berhane K, McConnell R, Kuenzli N, Lurmann F, Rappaport E, Margolis H, Bates D, Peters J. The effect of air pollution on lung development from 10 to 18 years of age. N Engl J Med. 2004 Sep 9; 351(11):1057-67. View in: PubMed

Salo PM, Xia J, Johnson CA, Li Y, Avol EL, Gong J, London SJ. Indoor allergens, asthma, and asthma-related symptoms among adolescents in Wuhan, China. Ann Epidemiol. 2004 Sep; 14(8):543-50. View in: PubMed

Mueller-Anneling L, Avol E, Peters JM, Thorne PS. Ambient endotoxin concentrations in PM10 from Southern California. Environ Health Perspect. 2004 Apr; 112(5):583-8. View in: PubMed

Salo PM, Xia J, Johnson CA, Li Y, Kissling GE, Avol EL, Liu C, London SJ. Respiratory symptoms in relation to residential coal burning and environmental tobacco smoke among early adolescents in Wuhan, China: a cross-sectional study. Environ Health. 2004; 3(1):14. View in: PubMed

McConnell R, Berhane K, Gilliland F, Molitor J, Thomas D, Lurmann F, Avol E, Gauderman WJ, Peters JM. Prospective study of air pollution and bronchitic symptoms in children with asthma. Am J Respir Crit Care Med. 2003 Oct 1; 168(7):790-7. View in: PubMed

Gilliland FD, Berhane K, Islam T, McConnell R, Gauderman WJ, Gilliland SS, Avol E, Peters JM. Obesity and the risk of newly diagnosed asthma in school-age children. Am J Epidemiol. 2003 Sep 1; 158(5):406-15. View in: PubMed

Künzli N, McConnell R, Bates D, Bastain T, Hricko A, Lurmann F, Avol E, Gilliland F, Peters J. Breathless in Los Angeles: the exhausting search for clean air. Am J Public Health. 2003 Sep; 93(9):1494-9. View in: PubMed

Gilliland FD, Li YF, Dubeau L, Berhane K, Avol E, McConnell R, Gauderman WJ, Peters JM. Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children. Am J Respir Crit Care Med. 2002 Aug 15; 166(4):457-63. View in: PubMed

Gauderman WJ, Gilliland GF, Vora H, Avol E, Stram D, McConnell R, Thomas D, Lurmann F, Margolis HG, Rappaport EB, Berhane K, Peters JM. Association between air pollution and lung function growth in southern California children: results from a second cohort. Am J Respir Crit Care Med. 2002 Jul 1; 166(1):76-84. View in: PubMed

McConnell R, Berhane K, Gilliland F, Islam T, Gauderman WJ, London SJ, Avol E, Rappaport EB, Margolis HG, Peters JM. Indoor risk factors for asthma in a prospective study of adolescents. Epidemiology. 2002 May; 13(3):288-95. View in: PubMed

McConnell R, Berhane K, Gilliland F, London SJ, Islam T, Gauderman WJ, Avol E, Margolis HG, Peters JM. Asthma in exercising children exposed to ozone: a cohort study. Lancet. 2002 Feb 2; 359(9304):386-91. View in: PubMed

Avol EL, Gauderman WJ, Tan SM, London SJ, Peters JM. Respiratory effects of relocating to areas of differing air pollution levels. Am J Respir Crit Care Med. 2001 Dec 1; 164(11):2067-72. View in: PubMed

Peters JM, Avol E, Navidi W, London SJ, Gauderman WJ, Lurmann F, Linn WS, Margolis H, Rappaport E, Gong H, Thomas DC. A study of twelve Southern California communities with differing levels and types of air pollution. I. Prevalence of respiratory morbidity. Am J Respir Crit Care Med. 1999 Mar; 159(3):760-7. View in: PubMed

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