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Edy Soffer, MD
Professor of Clinical Medicine
HCC 322P Health Sciences Campus Los Angeles


Edy E. Soffer, MD is Director of the GI Motility program at the Division of Gastroenterology, Keck School of Medicine of USC. Dr. Soffer's primary areas of research interest involve innovative treatments for gastroesophageal reflux disease and gastroparesis. His research has received funding from the American College of Gastroenterology, the BIRD Foundation, and several pharmaceutical companies.

Board certified in Internal Medicine with a subspecialty in gastroenterology, Dr. Soffer is a member of the American College of Gastroenterology, American Gastroenterological Association and American Motility Society. He has written articles for numerous peer-reviewed publications, including American Journal of Gastroenterology, American Journal of Physiology, Neurogastroenterology & Motility, Digestive Diseases and Sciences, and Medical Engineering and Technology.

Dr. Soffer received his medical degree from Technion School of Medicine in Haifa, Israel. He completed internships at Soroka Medical Center in Beer-Sheva, Israel and at Coney Island Hospital in New York, where he also completed a residency in internal medicine. Dr. Soffer fulfilled a fellowship in gastroenterology at the University of Tennessee Center for Health Sciences in Memphis and research fellowships at the University of Iowa Hospital/Clinic in Iowa City and at London Hospital Medical College in England.


Editorial Board of Neurogastroenterology and Motility: Most Cited Manuscript Award, 2004

Asia Pacific Digestive Week: Presidential Award, 2012


Rodríguez L, Rodriguez PA, Gómez B, Netto MG, Crowell MD, Soffer E. Electrical stimulation therapy of the lower esophageal sphincter is successful in treating GERD: long-term 3-year results. Surg Endosc. 2016 Jul; 30(7):2666-72. View in: PubMed

Soffer E, Rodríguez L, Rodriguez P, Gómez B, Neto MG, Crowell MD. Effect of electrical stimulation of the lower esophageal sphincter in gastroesophageal reflux disease patients refractory to proton pump inhibitors. World J Gastrointest Pharmacol Ther. 2016 Feb 6; 7(1):145-55. View in: PubMed

Kim SE, Soffer E. Electrical stimulation for gastroesophageal reflux disease: current state of the art. Clin Exp Gastroenterol. 2016; 9:11-9. View in: PubMed

Chiu J, Soffer E. Novel surgical options for gastroesophageal reflux disease. Expert Rev Gastroenterol Hepatol. 2015 Jul; 9(7):943-51. View in: PubMed

Rodríguez L, Rodriguez P, Gómez B, Ayala JC, Oxenberg D, Perez-Castilla A, Netto MG, Soffer E, Boscardin WJ, Crowell MD. Two-year results of intermittent electrical stimulation of the lower esophageal sphincter treatment of gastroesophageal reflux disease. Surgery. 2015 Mar; 157(3):556-67. View in: PubMed

Chiu JD, Soffer E. Gastric electrical stimulation for obesity. Curr Gastroenterol Rep. 2015 Jan; 17(1):424. View in: PubMed

Hoppo T, Rodríguez L, Soffer E, Crowell MD, Jobe BA. Long-term results of electrical stimulation of the lower esophageal sphincter for treatment of proximal GERD. Surg Endosc. 2014 Dec; 28(12):3293-301. View in: PubMed

Ford AC, Moayyedi P, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Quigley EM. American college of gastroenterology monograph on the management of irritable bowel syndrome and chronic idiopathic constipation. Am J Gastroenterol. 2014 Aug; 109 Suppl 1:S2-S26. View in: PubMed

Jamil LH, Huang BL, Kunkel DC, Jayaraman V, Soffer EE. Successful gastric volvulus reduction and gastropexy using a dual endoscope technique. Case Rep Med. 2014; 2014:136381. View in: PubMed

Chan OT, Chiles L, Levy M, Zhai J, Yerian LM, Xu H, Xiao SY, Soffer EE, Conklin JL, Dhall D, Kahn ME, Balzer BL, Amin MB, Wang HL. Smoothelin expression in the gastrointestinal tract: implication in colonic inertia. Appl Immunohistochem Mol Morphol. 2013 Oct; 21(5):452-9. View in: PubMed

Basseri B, Pimentel M, Chang C, Soffer EE, Conklin JL. Recorded lower esophageal pressures as a function of electronic sleeve placement and location of gastric pressure measurement in patients with hiatal hernia. J Neurogastroenterol Motil. 2013 Oct; 19(4):479-84. View in: PubMed

Basseri B, Vasiliauskas EA, Chan O, Wang HL, Basseri RJ, Pimentel M, Soffer E, Conklin JL. Evaluation of peripapillary lymphocytosis and lymphocytic esophagitis in adult inflammatory bowel disease. Gastroenterol Hepatol (N Y). 2013 Aug; 9(8):505-11. View in: PubMed

Wang Y, Gong H, Lopez R, Lian L, Kiran RP, Soffer EE, Shen B. Correlation between serum serotonin and endoscopy inflammation scores in patients with ileal pouches. J Crohns Colitis. 2013 May; 7(4):e133-42. View in: PubMed

Ardila-Hani A, Arabyan M, Waxman A, Ih G, Berel D, Pimentel M, Conklin J, Soffer EE. Severity of dyspeptic symptoms correlates with delayed and early variables of gastric emptying. Dig Dis Sci. 2013 Feb; 58(2):478-87. View in: PubMed

Soffer EE. Gastric electrical stimulation for gastroparesis. J Neurogastroenterol Motil. 2012 Apr; 18(2):131-7. View in: PubMed

Basseri RJ, Basseri B, Pimentel M, Chong K, Youdim A, Low K, Hwang L, Soffer E, Chang C, Mathur R. Intestinal methane production in obese individuals is associated with a higher body mass index. Gastroenterol Hepatol (N Y). 2012 Jan; 8(1):22-8. View in: PubMed

Basseri B, Pimentel M, Shaye OA, Low K, Soffer EE, Conklin JL. Apple sauce improves detection of esophageal motor dysfunction during high-resolution manometry evaluation of dysphagia. Dig Dis Sci. 2011 Jun; 56(6):1723-8. View in: PubMed

Jee SR, Morales W, Low K, Chang C, Zhu A, Pokkunuri V, Chatterjee S, Soffer E, Conklin JL, Pimentel M. ICC density predicts bacterial overgrowth in a rat model of post-infectious IBS. World J Gastroenterol. 2010 Aug 7; 16(29):3680-6. View in: PubMed

Jee SR, Pimentel M, Soffer E, Conklin JL. A high-resolution view of achalasia. J Clin Gastroenterol. 2009 Aug; 43(7):644-51. View in: PubMed

Sanmiguel CP, Conklin JL, Cunneen SA, Barnett P, Phillips EH, Kipnes M, Pilcher J, Soffer EE. Gastric electrical stimulation with the TANTALUS System in obese type 2 diabetes patients: effect on weight and glycemic control. J Diabetes Sci Technol. 2009 Jul; 3(4):964-70. View in: PubMed

Sanmiguel CP, Ito Y, Hagiike M, Conklin JL, Lalezari D, Soffer EE. The effect of eating on lower esophageal sphincter electrical activity. Am J Physiol Gastrointest Liver Physiol. 2009 Apr; 296(4):G793-7. View in: PubMed

Chen GC, Cheng DW, Enayati PJ, Chen G, Conklin JL, Soffer EE. Concurrent findings of achalasia and duodenal duplication in a Down syndrome patient. J Formos Med Assoc. 2009 Jan; 108(1):78-81. View in: PubMed

Brody F, Vaziri K, Saddler A, Ali A, Drenon E, Hanna B, Akin E, Gonzalez F, Soffer E. Gastric electrical stimulation for gastroparesis. J Am Coll Surg. 2008 Oct; 207(4):533-8. View in: PubMed

Sanmiguel CP, Hagiike M, Mintchev MP, Cruz RD, Phillips EH, Cunneen SA, Conklin JL, Soffer EE. Effect of electrical stimulation of the LES on LES pressure in a canine model. Am J Physiol Gastrointest Liver Physiol. 2008 Aug; 295(2):G389-94. View in: PubMed

Sanmiguel CP, Haddad W, Aviv R, Cunneen SA, Phillips EH, Kapella W, Soffer EE. The TANTALUS system for obesity: effect on gastric emptying of solids and ghrelin plasma levels. Obes Surg. 2007 Nov; 17(11):1503-9. View in: PubMed

Brody F, Nam A, Drenon E, Ali A, Soffer E. Laparoscopic insertion of gastric electrodes for electrical stimulation. J Laparoendosc Adv Surg Tech A. 2007 Feb; 17(1):1-6. View in: PubMed

Xing J, Felsher J, Brody F, Soffer E. Gastric electrical stimulation significantly increases canine lower esophageal sphincter pressure. Dig Dis Sci. 2005 Aug; 50(8):1481-7. View in: PubMed

Nayar DS, Khandwala F, Achkar E, Shay SS, Richter JE, Falk GW, Soffer EE, Vaezi MF. Esophageal manometry: assessment of interpreter consistency. Clin Gastroenterol Hepatol. 2005 Mar; 3(3):218-24. View in: PubMed

Brody F, Chand B, Brodsky J, Soffer E. Laparoscopic revision of gastric pacing wires. J Laparoendosc Adv Surg Tech A. 2004 Jun; 14(3):187-9. View in: PubMed

Sanmiguel C, Soffer EE. Intestinal dysmotility and its relationship to sphincter of Oddi dysfunction. Curr Gastroenterol Rep. 2004 Apr; 6(2):137-9. View in: PubMed

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