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Fariba Navid

Professor of Clinical Pediatrics

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Phone +1 323 361 2762
Email fnavid@chla.usc.edu
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Publications

  • An Exome Capture-Based RNA-Sequencing Assay for Genome-Wide Identification and Prioritization of Clinically Important Fusions in Pediatric Tumors J Mol Diagn. 2024 Feb; 26(2):127-139. . View in PubMed
  • Combined low-pass whole genome and targeted sequencing in liquid biopsies for pediatric solid tumors NPJ Precis Oncol. 2023 Feb 20; 7(1):21. . View in PubMed
  • Survival outcomes and surgical morbidity based on surgical approach to pulmonary metastasectomy in pediatric, adolescent and young adult patients with osteosarcoma Cancer Med. 2023 10; 12(20):20231-20241. . View in PubMed
  • Phase I trial of Ganitumab plus Dasatinib to Cotarget the Insulin-Like Growth Factor 1 Receptor and Src Family Kinase YES in Rhabdomyosarcoma Clin Cancer Res. 2023 09 01; 29(17):3329-3339. . View in PubMed
  • The Role of Pharmacotherapeutic Agents in Children with Desmoid Tumors Paediatr Drugs. 2022 Sep; 24(5):433-445. . View in PubMed
  • Primary Adrenal Malignant Rhabdoid Tumor in a 14-Year-Old Female: A Case Report and Literature Review Int J Surg Pathol. 2022 Apr; 30(2):172-176. . View in PubMed
  • Kaposiform hemangioendothelioma of the bone in children and adolescents Pediatr Blood Cancer. 2022 01; 69(1):e29392. . View in PubMed
  • Improved Outcome in Children With Newly Diagnosed High-Risk Neuroblastoma Treated With Chemoimmunotherapy: Updated Results of a Phase II Study Using hu1418K322A. J Clin Oncol. 2022 02 01; 40(4):335-344. . View in PubMed
  • A multidisciplinary approach to management of abdominal lymphatic malformations J Pediatr Surg. 2021 Aug; 56(8):1425-1429. . View in PubMed
  • Charting a path for prioritization of novel agents for clinical trials in osteosarcoma: A report from the Children’s Oncology Group New Agents for Osteosarcoma Task Force Pediatr Blood Cancer. 2021 09; 68(9):e29188. . View in PubMed
  • Rationale for the use of tyrosine kinase inhibitors in the treatment of paediatric desmoid-type fibromatosis Br J Cancer. 2021 05; 124(10):1637-1646. . View in PubMed
  • Custom Pediatric Oncology Next-Generation Sequencing Panel Identifies Somatic Mosaicism in Archival Tissue and Enhances Targeted Clinical Care Pediatr Neurol. 2021 01; 114:55-59. . View in PubMed
  • Phase I expansion cohort to evaluate the combination of bevacizumab, sorafenib and low-dose cyclophosphamide in children and young adults with refractory or recurrent solid tumours Eur J Cancer. 2020 06; 132:35-42. . View in PubMed
  • Pre-existing antitherapeutic antibodies against the Fc region of the hu1418K322A mAb are associated with outcome in patients with relapsed neuroblastoma. J Immunother Cancer. 2020 03; 8(1). . View in PubMed
  • A Phase 1 and pharmacokinetic study evaluating daily or weekly schedules of the humanized anti-GD2 antibody hu1418K322A in recurrent/refractory solid tumors. MAbs. 2020 Jan-Dec; 12(1):1773751. . View in PubMed
  • Embryonal rhabdomyosarcoma in a patient with a germline CBL pathogenic variant Cancer Genet. 2019 02; 231-232:62-66. . View in PubMed
  • Integrated analysis of long-term growth and bone development in pediatric and adolescent patients receiving bevacizumab Pediatr Blood Cancer. 2019 02; 66(2):e27487. . View in PubMed
  • Sorafenib Population Pharmacokinetics and Skin Toxicities in Children and Adolescents with Refractory/Relapsed Leukemia or Solid Tumor Malignancies Clin Cancer Res. 2019 12 15; 25(24):7320-7330. . View in PubMed
  • A Phase II Trial of Hu1418K322A in Combination with Induction Chemotherapy in Children with Newly Diagnosed High-Risk Neuroblastoma. Clin Cancer Res. 2019 11 01; 25(21):6320-6328. . View in PubMed
  • The role of routine imaging in pediatric cutaneous melanoma Pediatr Blood Cancer. 2018 12; 65(12):e27412. . View in PubMed
  • Health-Related Quality of Life and Survival Outcomes of Pediatric Patients With Nonmetastatic Osteosarcoma Treated in Countries With Different Resources J Glob Oncol. 2018 09; 4:1-11. . View in PubMed
  • Prognostic Value of Metabolic and Volumetric Parameters of FDG PET in Pediatric Osteosarcoma: A Hypothesis-generating Study Radiology. 2018 04; 287(1):303-312. . View in PubMed
  • 18F-FDG Uptake During Early Adjuvant Chemotherapy Predicts Histologic Response in Pediatric and Young Adult Patients with Osteosarcoma J Nucl Med. 2018 01; 59(1):25-30. . View in PubMed
  • Multi-level otsu method to define metabolic tumor volume in positron emission tomography Am J Nucl Med Mol Imaging. 2018; 8(6):373-386. . View in PubMed
  • Prospective study of neuropathic pain after definitive surgery for extremity osteosarcoma in a pediatric population Pediatr Blood Cancer. 2017 03; 64(3). . View in PubMed
  • A phase II trial evaluating the feasibility of adding bevacizumab to standard osteosarcoma therapy Int J Cancer. 2017 10 01; 141(7):1469-1477. . View in PubMed
  • Use of Quantitative Dynamic Contrast-Enhanced Ultrasound to Assess Response to Antiangiogenic Therapy in Children and Adolescents With Solid Malignancies: A Pilot Study AJR Am J Roentgenol. 2016 May; 206(5):933-9. . View in PubMed
  • Pulmonary Function after Treatment for Childhood CancerA Report from the St. Jude Lifetime Cohort Study (SJLIFE). Ann Am Thorac Soc. 2016 09; 13(9):1575-85. . View in PubMed
  • Comparison of (18) F-FDG-PET-CT and Bone Scintigraphy for Evaluation of Osseous Metastases in Newly Diagnosed and Recurrent Osteosarcoma Pediatr Blood Cancer. 2016 08; 63(8):1381-6. . View in PubMed
  • Feasibility of Pegylated Interferon in Children and Young Adults With Resected High-Risk Melanoma Pediatr Blood Cancer. 2016 07; 63(7):1207-13. . View in PubMed
  • In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments Cancer Res. 2016 07 01; 76(13):3929-41. . View in PubMed
  • Bevacizumab dosing strategy in paediatric cancer patients based on population pharmacokinetic analysis with external validation Br J Clin Pharmacol. 2016 Jan; 81(1):148-60. . View in PubMed
  • Limited Margin Radiation Therapy for Children and Young Adults With Ewing Sarcoma Achieves High Rates of Local Tumor Control Int J Radiat Oncol Biol Phys. 2016 09 01; 96(1):119-26. . View in PubMed
  • Pediatric Melanoma and Atypical Melanocytic Neoplasms Cancer Treat Res. 2016; 167:331-69. . View in PubMed
  • Assessing vascular effects of adding bevacizumab to neoadjuvant chemotherapy in osteosarcoma using DCE-MRI Br J Cancer. 2015 Nov 03; 113(9):1282-8. . View in PubMed
  • Comparable efficacy with varying dosages of glucarpidase in pediatric oncology patients Pediatr Blood Cancer. 2015 Sep; 62(9):1518-22. . View in PubMed
  • Pneumothorax as a complication of combination antiangiogenic therapy in children and young adults with refractory/recurrent solid tumors J Pediatr Surg. 2015 Sep; 50(9):1484-9. . View in PubMed
  • FDG PET/CT imaging of desmoplastic small round cell tumor: findings at staging, during treatment and at follow-up Pediatr Radiol. 2015 Aug; 45(9):1308-15. . View in PubMed
  • Ocular abnormalities in patients treated with a novel anti-GD2 monoclonal antibody, hu1418K322A. J AAPOS. 2015 Apr; 19(2):112-5. . View in PubMed
  • Vincristine and Dactinomycin in Infantile Myofibromatosis With a Review of Treatment Options J Pediatr Hematol Oncol. 2015 Apr; 37(3):237-41. . View in PubMed
  • The genomic landscape of childhood and adolescent melanoma J Invest Dermatol. 2015 Mar; 135(3):816-823. . View in PubMed
  • Comparison of pain outcomes between two anti-GD2 antibodies in patients with neuroblastoma Pediatr Blood Cancer. 2015 02; 62(2):224-228. . View in PubMed
  • Influence of bony resection margins and surgicopathological factors on outcomes in limb-sparing surgery for extremity osteosarcoma Pediatr Blood Cancer. 2015 02; 62(2):246-251. . View in PubMed
  • An approach to renal masses in pediatrics Pediatrics. 2015 Jan; 135(1):142-58. . View in PubMed
  • Long-term pulmonary function after metastasectomy for childhood osteosarcoma: a report from the St Jude lifetime cohort study J Am Coll Surg. 2014 Aug; 219(2):265-71. . View in PubMed
  • Management of local recurrence of pediatric osteosarcoma following limb-sparing surgery Ann Surg Oncol. 2014 Jun; 21(6):1948-55. . View in PubMed
  • Population pharmacokinetics of bevacizumab in children with osteosarcoma: implications for dosing Clin Cancer Res. 2014 May 15; 20(10):2783-92. . View in PubMed
  • Phase I trial of a novel anti-GD2 monoclonal antibody, Hu1418K322A, designed to decrease toxicity in children with refractory or recurrent neuroblastoma. J Clin Oncol. 2014 May 10; 32(14):1445-52. . View in PubMed
  • Safety of ultrasound contrast agents in the pediatric oncologic population: a single-institution experience AJR Am J Roentgenol. 2014 May; 202(5):966-70. . View in PubMed
  • Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma Cell Rep. 2014 Apr 10; 7(1):104-12. . View in PubMed
  • Hypersensitivity reaction to high-dose methotrexate and successful rechallenge in a pediatric patient with osteosarcoma Pediatr Blood Cancer. 2014 Feb; 61(2):373-5. . View in PubMed
  • A Phase II multicenter, open-label, clinical and pharmokinetic trial of PM00104 in patients with advanced Ewing Family of Tumors Invest New Drugs. 2014 Feb; 32(1):171-7. . View in PubMed
  • Alternative formulations of sorafenib for use in children Pediatr Blood Cancer. 2013 Oct; 60(10):1642-6. . View in PubMed
  • Lack of specificity of plasma concentrations of inhibin B and follicle-stimulating hormone for identification of azoospermic survivors of childhood cancer: a report from the St Jude lifetime cohort study J Clin Oncol. 2013 Apr 01; 31(10):1324-8. . View in PubMed
  • Enhancement of the anti-melanoma response of Hu1418K322A by aCD40 + CpG. Cancer Immunol Immunother. 2013 Apr; 62(4):665-75. . View in PubMed
  • Phase I and clinical pharmacology study of bevacizumab, sorafenib, and low-dose cyclophosphamide in children and young adults with refractory/recurrent solid tumors Clin Cancer Res. 2013 Jan 01; 19(1):236-46. . View in PubMed
  • Analysis of prognostic factors in extraosseous Ewing sarcoma family of tumors: review of StJude Children’s Research Hospital experience. Ann Surg Oncol. 2012 Nov; 19(12):3816-22. . View in PubMed
  • Timing of surgery and the role of adjuvant radiotherapy in ewing sarcoma of the chest wall: a single-institution experience Ann Surg Oncol. 2012 Nov; 19(12):3809-15. . View in PubMed
  • 64Cu-p-NH2-Bn-DOTA-hu1418K322A, a PET radiotracer targeting neuroblastoma and melanoma. J Nucl Med. 2012 Nov; 53(11):1772-8. . View in PubMed
  • Clinical management of Ewing sarcoma of the bones of the hands and feet: a retrospective single-institution review J Pediatr Surg. 2012 Oct; 47(10):1806-10. . View in PubMed
  • Disseminated carcinoma ex pleomorphic adenoma in an adolescent confirmed by application of PLAG1 immunohistochemistry and FISH for PLAG1 rearrangement Head Neck Pathol. 2012 Sep; 6(3):377-83. . View in PubMed
  • Management of melanomas in children and young adults J Pediatr Hematol Oncol. 2012 May; 34 Suppl 2:S51-4. . View in PubMed
  • Dose escalation of intravenous irinotecan using oral cefpodoxime: a phase I study in pediatric patients with refractory solid tumors Pediatr Blood Cancer. 2012 Mar; 58(3):372-9. . View in PubMed
  • Genetic alterations in childhood melanoma Am Soc Clin Oncol Educ Book. 2012; 589-92. . View in PubMed
  • Jaw dysfunction related to pterygoid and masseter muscle dosimetry after radiation therapy in children and young adults with head-and-neck sarcomas Int J Radiat Oncol Biol Phys. 2012 Jan 01; 82(1):355-60. . View in PubMed
  • Safety and immunogenicity of live attenuated and inactivated influenza vaccines in children with cancer J Infect Dis. 2011 Nov 15; 204(10):1475-82. . View in PubMed
  • Quantitation of sorafenib and its active metabolite sorafenib N-oxide in human plasma by liquid chromatography-tandem mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Nov 01; 878(29):3033-8. . View in PubMed
  • Caveolin-1 modulates the ability of Ewing’s sarcoma to metastasize Mol Cancer Res. 2010 Nov; 8(11):1489-500. . View in PubMed
  • Anti-GD2 antibody therapy for GD2-expressing tumors Curr Cancer Drug Targets. 2010 Mar; 10(2):200-9. . View in PubMed
  • Preliminary results from a prospective study using limited margin radiotherapy in pediatric and young adult patients with high-grade nonrhabdomyosarcoma soft-tissue sarcoma Int J Radiat Oncol Biol Phys. 2010 Mar 01; 76(3):874-8. . View in PubMed
  • Stability of cyclophosphamide in extemporaneous oral suspensions Ann Pharmacother. 2010 Feb; 44(2):295-301. . View in PubMed
  • Phase II trial of ixabepilone administered daily for five days in children and young adults with refractory solid tumors: a report from the children’s oncology group Clin Cancer Res. 2010 Jan 15; 16(2):750-4. . View in PubMed
  • Body wall and visceral nonrhabdomyosarcoma soft tissue sarcomas in children and adolescents J Pediatr Surg. 2009 Oct; 44(10):1965-71. . View in PubMed
  • Tyrosine kinase inhibitor enhances the bioavailability of oral irinotecan in pediatric patients with refractory solid tumors J Clin Oncol. 2009 Sep 20; 27(27):4599-604. . View in PubMed
  • Sperm cryopreservation practices among adolescent cancer patients at risk for infertility Pediatr Hematol Oncol. 2009 Jun; 26(4):252-60. . View in PubMed
  • Immune therapies for neuroblastoma Cancer Biol Ther. 2009 May; 8(10):874-82. . View in PubMed
  • Combination of gemcitabine and docetaxel in the treatment of children and young adults with refractory bone sarcoma Cancer. 2008 Jul 15; 113(2):419-25. . View in PubMed
  • Stability of sunitinib in oral suspension Ann Pharmacother. 2008 Jul; 42(7):962-6. . View in PubMed
  • Pulmonary nodules discovered during the initial evaluation of pediatric patients with bone and soft-tissue sarcoma Pediatr Blood Cancer. 2008 Jun; 50(6):1147-53. . View in PubMed
  • Second cancers in patients with the Ewing sarcoma family of tumours Eur J Cancer. 2008 May; 44(7):983-91. . View in PubMed
  • Prognostic factors for local and distant control in Ewing sarcoma family of tumors Ann Oncol. 2008 Apr; 19(4):814-20. . View in PubMed
  • Desmoplastic small round cell tumor in childhood: the StJude Children’s Research Hospital experience. Pediatr Blood Cancer. 2007 Sep; 49(3):274-9. . View in PubMed
  • Analysis of prognostic factors in ewing sarcoma family of tumors: review of StJude Children’s Research Hospital studies. Cancer. 2007 Jul 15; 110(2):375-84. . View in PubMed
  • A model for quantitative changes in the magnetic resonance parameters of muscle in children after therapeutic irradiation Magn Reson Imaging. 2006 Dec; 24(10):1319-24. . View in PubMed
  • Pharmacologic inhibition of cyclin-dependent kinase 4/6 activity arrests proliferation in myoblasts and rhabdomyosarcoma-derived cells Mol Cancer Ther. 2006 May; 5(5):1299-308. . View in PubMed
  • Concomitant administration of vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide for high-risk sarcomas: the StJude Children’s Research Hospital experience. Cancer. 2006 Apr 15; 106(8):1846-56. . View in PubMed
  • STAT3 is activated in a subset of the Ewing sarcoma family of tumours J Pathol. 2006 Apr; 208(5):624-32. . View in PubMed
  • The feasibility of adjuvant interferon alpha-2b in children with high-risk melanoma Cancer. 2005 Feb 15; 103(4):780-7. . View in PubMed
  • Low Dose Histone Deacetylase Inhibitor, Depsipeptide (FR901228), Promotes Adenoviral Transduction in Human Rhabdomyosarcoma Cell Lines Sarcoma. 2004; 8(1):25-30. . View in PubMed
  • Autocrine Transforming Growth Factor-beta Growth Pathway in Murine Osteosarcoma Cell Lines Associated with Inability to Affect Phosphorylation of Retinoblastoma Protein Sarcoma. 2000; 4(3):93-102. . View in PubMed
  • Acute lymphoblastic leukemia with the (8;14)(q24;q32) translocation and FAB L3 morphology associated with a B-precursor immunophenotype: the Pediatric Oncology Group experience Leukemia. 1999 Jan; 13(1):135-41. . View in PubMed
  • AP-2 may contribute to IGF-II overexpression in rhabdomyosarcoma Oncogene. 1998 Sep 10; 17(10):1261-70. . View in PubMed
  • Albumin, IgG, retinol-binding protein, and alpha1-microglobulin excretion in childhood Pediatr Nephrol. 1998 May; 12(4):290-2. . View in PubMed

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