Back to Index
Francis Swaby Markland, PhD
Professor of Biochemistry & Molecular Biology
Biochemistry and Molecular Biology
HMR 813, 2011 Zonal Ave. Off Campus Los Angeles
+1 323 442 2747


Janib SM, Gustafson JA, Minea RO, Swenson SD, Liu S, Pastuszka MK, Lock LL, Cui H, Markland FS, Conti PS, Li Z, MacKay JA. Multimeric disintegrin protein polymer fusions that target tumor vasculature. Biomacromolecules. 2014 Jul 14; 15(7):2347-58. View in: PubMed

Levine M, Swenson S, McCormick T, Henderson SO, Thomas SH, Markland FS. Reversal of thienopyridine-induced platelet dysfunction following desmopressin administration. J Med Toxicol. 2013 Jun; 9(2):139-43. View in: PubMed

Markland FS, Swenson S. Snake venom metalloproteinases. Toxicon. 2013 Feb; 62:3-18. View in: PubMed

Lee JY, Markland FS, Lucchesi BR. Hirudin and s18886 maintain luminal patency after thrombolysis with alfimeprase. J Cardiovasc Pharmacol. 2013 Feb; 61(2):152-9. View in: PubMed

Minea R, Helchowski C, Rubino B, Brodmann K, Swenson S, Markland F. Development of a chimeric recombinant disintegrin as a cost-effective anti-cancer agent with promising translational potential. Toxicon. 2012 Mar 15; 59(4):472-86. View in: PubMed

Hubbard S, Choudhary S, Maus E, Shukla D, Swenson S, Markland FS, Tiwari V. Contortrostatin, a homodimeric disintegrin isolated from snake venom inhibits herpes simplex virus entry and cell fusion. Antivir Ther. 2012; 17(7):1319-26. View in: PubMed

Lin E, Wang Q, Swenson S, Jadvar H, Groshen S, Ye W, Markland FS, Pinski J. The disintegrin contortrostatin in combination with docetaxel is a potent inhibitor of prostate cancer in vitro and in vivo. Prostate. 2010 Sep 1; 70(12):1359-70. View in: PubMed

Markland FS, Swenson S. Fibrolase: trials and tribulations. Toxins (Basel). 2010 Apr; 2(4):793-808. View in: PubMed

Minea RO, Helchowski CM, Zidovetzki SJ, Costa FK, Swenson SD, Markland FS. Vicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activities. PLoS One. 2010; 5(6):e10929. View in: PubMed

Helchowski CM, Minea RO, Swenson SD, Markland FS. The use of pepsin in receptor internalization assays. Biochem Biophys Res Commun. 2009 Oct 16; 388(2):240-6. View in: PubMed

Moiseeva N, Bau R, Swenson SD, Markland FS, Choe JY, Liu ZJ, Allaire M. Structure of acostatin, a dimeric disintegrin from Southern copperhead (Agkistrodon contortrix contortrix), at 1. 7 A resolution. Acta Crystallogr D Biol Crystallogr. 2008 Apr; 64(Pt 4):466-70. View in: PubMed

Swenson S, Ramu S, Markland FS. Anti-angiogenesis and RGD-containing snake venom disintegrins. Curr Pharm Des. 2007; 13(28):2860-71. View in: PubMed

Pyrko P, Wang W, Markland FS, Swenson SD, Schmitmeier S, Schönthal AH, Chen TC. The role of contortrostatin, a snake venom disintegrin, in the inhibition of tumor progression and prolongation of survival in a rodent glioma model. J Neurosurg. 2005 Sep; 103(3):526-37. View in: PubMed

Schmitmeier S, Markland FS, Schönthal AH, Chen TC. Potent mimicry of fibronectin-induced intracellular signaling in glioma cells by the homodimeric snake venom disintegrin contortrostatin. Neurosurgery. 2005 Jul; 57(1):141-53; discussion 141-53. View in: PubMed

Swenson S, Markland FS. Snake venom fibrin(ogen)olytic enzymes. Toxicon. 2005 Jun 15; 45(8):1021-39. View in: PubMed

Minea R, Swenson S, Costa F, Chen TC, Markland FS. Development of a novel recombinant disintegrin, contortrostatin, as an effective anti-tumor and anti-angiogenic agent. Pathophysiol Haemost Thromb. 2005; 34(4-5):177-83. View in: PubMed

Swenson S, Costa F, Ernst W, Fujii G, Markland FS. Contortrostatin, a snake venom disintegrin with anti-angiogenic and anti-tumor activity. Pathophysiol Haemost Thromb. 2005; 34(4-5):169-76. View in: PubMed

Golubkov V, Garcia A, Markland FS. Action of fenretinide (4-HPR) on ovarian cancer and endothelial cells. Anticancer Res. 2005 Jan-Feb; 25(1A):249-53. View in: PubMed

Swenson S, Costa F, Minea R, Sherwin RP, Ernst W, Fujii G, Yang D, Markland FS. Intravenous liposomal delivery of the snake venom disintegrin contortrostatin limits breast cancer progression. Mol Cancer Ther. 2004 Apr; 3(4):499-511. View in: PubMed

Golubkov V, Hawes D, Markland FS. Anti-angiogenic activity of contortrostatin, a disintegrin from Agkistrodon contortrix contortrix snake venom. Angiogenesis. 2003; 6(3):213-24. View in: PubMed

Schmitmeier S, Markland FS, Ritter MR, Sawcer DE, Chen TC. Functional effect of contortrostatin, a snake venom disintegrin, on human glioma cell invasion in vitro. Cell Commun Adhes. 2003 Jan-Feb; 10(1):1-16. View in: PubMed

Moiseeva N, Swenson SD, Markland FS, Bau R. Purification, crystallization and preliminary X-ray analysis of the disintegrin contortrostatin from Agkistrodon contortrix contortrix snake venom. Acta Crystallogr D Biol Crystallogr. 2002 Dec; 58(Pt 12):2122-4. View in: PubMed

Markland FS, Shieh K, Zhou Q, Golubkov V, Sherwin RP, Richters V, Sposto R. A novel snake venom disintegrin that inhibits human ovarian cancer dissemination and angiogenesis in an orthotopic nude mouse model. Haemostasis. 2001 May-Dec; 31(3-6):183-91. View in: PubMed

Powered bySC CTSI