Faculty

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Frank L. Acosta, MD
Associate Professor of Clinical Neurological Surgery
Neurological Surgery
DEI 5501 Off Campus Los Angeles
+1 323 226 7421

Overview

Dr. Acosta brings depth to our team as a highly talented neurosurgeon, fellowship trained in complex spine deformity. His outstanding academic and research credentials accelerates our understanding of various spine pathologies and lead us to new translational discoveries.

Publications

Bow Hunter's Syndrome: Surgical Management (Video) and Review of the Literature. World Neurosurg. 2017 Jul; 103:953. e7-953. e12. View in: PubMed

Transpedicular Corpectomy and Cage Placement in the Treatment of Traumatic Lumbar Burst Fractures. Clin Spine Surg. 2017 Oct; 30(8):360-366. View in: PubMed

The use of a novel perfusion-based cadaveric simulation model with cerebrospinal fluid reconstitution comparing dural repair techniques: a pilot study. Spine J. 2017 Sep; 17(9):1335-1341. View in: PubMed

Biomechanical analysis of lateral interbody fusion strategies for adjacent segment degeneration in the lumbar spine. Spine J. 2017 Jul; 17(7):1004-1011. View in: PubMed

Low-magnitude mechanical signals and the spine: A review of current and future applications. J Clin Neurosci. 2017 Jun; 40:18-23. View in: PubMed

The Clinical Correlations between Diabetes, Cigarette Smoking and Obesity on Intervertebral Degenerative Disc Disease of the Lumbar Spine. Asian Spine J. 2017 Jun; 11(3):337-347. View in: PubMed

Bisphosphonate's and Intermittent Parathyroid Hormone's Effect on Human Spinal Fusion: A Systematic Review of the Literature. Asian Spine J. 2017 Jun; 11(3):484-493. View in: PubMed

Semitendinosus Graft for Interspinous Ligament Reinforcement in Adult Spinal Deformity. Orthopedics. 2017 Jan 01; 40(1):e206-e210. View in: PubMed

Transpedicular Corpectomy and Cage Placement in the Treatment of Traumatic Lumbar Burst Fractures. Clin Spine Surg. 2016 Jul 14. View in: PubMed

Assessment of outcome following the use of recombinant human bone morphogenetic protein-2 for spinal fusion in the elderly population. J Neurosurg Sci. 2016 Jun; 60(2):256-71. View in: PubMed

Biomechanical Analysis of the Proximal Adjacent Segment after Multilevel Instrumentation of the Thoracic Spine: Do Hooks Ease the Transition? Global Spine J. Biomechanical Analysis of the Proximal Adjacent Segment after Multilevel Instrumentation of the Thoracic Spine: Do Hooks Ease the Transition? Global Spine J. 2016 Jun; 6(4):335-43. View in: PubMed

Emergency room resource utilization by patients with low-back pain. J Neurosurg Spine. 2016 May; 24(5):686-93. View in: PubMed

Effects of fusion and conservative treatment on disc degeneration and rates of subsequent surgery after thoracolumbar fracture. J Neurosurg Spine. 2016 Mar; 24(3):476-82. View in: PubMed

Stem cells and spinal fusion--are we there yet? Spine J. Stem cells and spinal fusion--are we there yet? Spine J. 2016 Mar; 16(3):400-1. View in: PubMed

Complications associated with the Dynesys dynamic stabilization system: a comprehensive review of the literature. Neurosurg Focus. 2016 Jan; 40(1):E2. View in: PubMed

Large solitary osteochondroma of the thoracic spine: Case report and review of the literature. Surg Neurol Int. 2016; 7(Suppl 13):S323-7. View in: PubMed

Evaluation of weekend admission on the prevalence of hospital acquired conditions in patients receiving thoracolumbar fusions. J Clin Neurosci. 2015 Aug; 22(8):1349-54. View in: PubMed

Evaluation of Effect of Weekend Admission on the Prevalence of Hospital-Acquired Conditions in Patients Receiving Cervical Fusions. World Neurosurg. 2015 Jul; 84(1):58-68. View in: PubMed

Novel application of pre-operative vertebral body embolization to reduce intraoperative blood loss during a three-column spinal osteotomy for non-oncologic spinal deformity. J Clin Neurosci. 2015 Apr; 22(4):765-7. View in: PubMed

Use of everolimus in renal transplant recipients: data from a national registry. Transplant Proc. 2014 Nov; 46(9):2991-5. View in: PubMed

First epidemiologic study in Argentina of the prevalence of BK viruria in kidney transplant patients. Transplant Proc. 2014 Nov; 46(9):3010-4. View in: PubMed

Retroperitoneal oblique corridor to the L2-S1 intervertebral discs in the lateral position: an anatomic study. J Neurosurg Spine. 2014 Nov; 21(5):785-93. View in: PubMed

Introduction: Costs and benefits of modern-day spine care. Neurosurg Focus. 2014 Jun; 36(6):Introduction. View in: PubMed

CT navigated lateral interbody fusion. J Clin Neurosci. 2013 Oct; 20(10):1438-41. View in: PubMed

Supra-psoas shallow docking in lateral interbody fusion. Neurosurgery. 2013 Sep; 73(1 Suppl Operative):ons48-51; discussion ons52. View in: PubMed

Cervical spine alignment, sagittal deformity, and clinical implications: a review. J Neurosurg Spine. 2013 Aug; 19(2):141-59. View in: PubMed

Deformity surgery. Response. J Neurosurg Spine. 2013 Apr; 18(4):415-6. View in: PubMed

Differences in treatments and outcomes for idiopathic scoliosis patients treated in the United States from 1998 to 2007: impact of socioeconomic variables and ethnicity. Spine J. 2013 Feb; 13(2):116-23. View in: PubMed

Direct lateral interbody fusion (DLIF) at the lumbosacral junction L5-S1. J Clin Neurosci. 2012 Jul; 19(7):1022-5. View in: PubMed

Implications of the center of rotation concept for the reconstruction of anterior column lordosis and axial preloads in spinal deformity surgery. J Neurosurg Spine. 2012 Jul; 17(1):43-56. View in: PubMed

Stem cell therapy for degenerative disc disease. Adv Orthop. 2012; 2012:961052. View in: PubMed

The potential for cellular therapy combined with growth factors in spinal cord injury. Stem Cells Int. 2012; 2012:826754. View in: PubMed

Porcine intervertebral disc repair using allogeneic juvenile articular chondrocytes or mesenchymal stem cells. Tissue Eng Part A. 2011 Dec; 17(23-24):3045-55. View in: PubMed

Morbidity and mortality after spinal deformity surgery in patients 75 years and older: complications and predictive factors. J Neurosurg Spine. 2011 Dec; 15(6):667-74. View in: PubMed

Minimally invasive lateral lumbar interbody fusion and transpsoas approach-related morbidity. Neurosurg Focus. 2011 Oct; 31(4):E4. View in: PubMed

Complications and outcomes after spinal deformity surgery in the elderly: review of the existing literature and future directions. Neurosurg Focus. 2011 Oct; 31(4):E3. View in: PubMed

Changes in coronal and sagittal plane alignment following minimally invasive direct lateral interbody fusion for the treatment of degenerative lumbar disease in adults: a radiographic study. J Neurosurg Spine. 2011 Jul; 15(1):92-6. View in: PubMed

Predicting ideal spinopelvic balance in adult spinal deformity. J Neurosurg Spine. 2011 Jul; 15(1):82-91. View in: PubMed

Treatment of Enneking stage 3 aggressive vertebral hemangiomas with intralesional spondylectomy: report of 10 cases and review of the literature. J Spinal Disord Tech. 2011 Jun; 24(4):268-75. View in: PubMed

Biomechanical analysis of cervicothoracic junction osteotomy in cadaveric model of ankylosing spondylitis: effect of rod material and diameter. J Neurosurg Spine. 2011 Mar; 14(3):330-5. View in: PubMed

Spinal surgery in patients with Parkinson's disease: experiences with the challenges posed by sagittal imbalance and the Parkinson's spine. Eur Spine J. 2010 Oct; 19(10):1785-94. View in: PubMed

En bloc resection for primary and metastatic tumors of the spine: a systematic review of the literature. Neurosurgery. 2010 Aug; 67(2):435-44; discussion 444-5. View in: PubMed

A biomechanical rationale for C1-ring osteosynthesis as treatment for displaced Jefferson burst fractures with incompetency of the transverse atlantal ligament. Eur Spine J. 2010 Aug; 19(8):1288-98. View in: PubMed

Effects of age on perioperative complications of extensive multilevel thoracolumbar spinal fusion surgery. J Neurosurg Spine. 2010 Apr; 12(4):402-8. View in: PubMed

[Demographic distribution and prevalence of overactive bladder in Venezuela]. Actas Urol Esp. 2010 Feb; 34(2):176-80. View in: PubMed

Results of the conversion to everolimus in renal transplant recipients with posttransplantation malignancies. Transplant Proc. 2010 Jan-Feb; 42(1):277-9. View in: PubMed

Study on accuracy and interobserver reliability of the assessment of odontoid fracture union using plain radiographs or CT scans. Eur Spine J. 2009 Nov; 18(11):1659-68. View in: PubMed

In vitro study of accuracy of cervical pedicle screw insertion using an electronic conductivity device (ATPS part III). Eur Spine J. 2009 Sep; 18(9):1300-13. View in: PubMed

Patient satisfaction and radiographic outcomes after lumbar spinal fusion without iliac crest bone graft or transverse process fusion. J Clin Neurosci. 2009 Sep; 16(9):1184-7. View in: PubMed

C2-fractures: part II. A morphometrical analysis of computerized atlantoaxial motion, anatomical alignment and related clinical outcomes. Eur Spine J. 2009 Aug; 18(8):1135-53. View in: PubMed

C2-fractures: part I. Quantitative morphology of the C2 vertebra is a prerequisite for the radiographic assessment of posttraumatic C2-alignment and the investigation of clinical outcomes. Eur Spine J. 2009 Jul; 18(7):978-91. View in: PubMed

Parasagittal osteotomy for en bloc resection of multilevel cervical chordomas. J Neurosurg Spine. 2009 May; 10(5):397-403. View in: PubMed

Perioperative complications and clinical outcomes of multilevel circumferential lumbar spinal fusion in the elderly. J Clin Neurosci. 2009 Jan; 16(1):69-73. View in: PubMed

Detection of postoperative granulation tissue with an ICG-enhanced integrated OI-/X-ray System. J Transl Med. 2008 Nov 27; 6:73. View in: PubMed

Long-term investigation of nonsurgical treatment for thoracolumbar and lumbar burst fractures: an outcome analysis in sight of spinopelvic balance. Eur Spine J. 2008 Aug; 17(8):1073-95. View in: PubMed

Percutaneous axial lumbar interbody fusion (AxiaLIF) of the L5-S1 segment: initial clinical and radiographic experience. Minim Invasive Neurosurg. 2008 Aug; 51(4):225-30. View in: PubMed

Complications and outcomes of lumbar spine surgery in elderly people: a review of the literature. J Am Geriatr Soc. 2008 Jul; 56(7):1318-27. View in: PubMed

Long-term biomechanical stability and clinical improvement after extended multilevel corpectomy and circumferential reconstruction of the cervical spine using titanium mesh cages. J Spinal Disord Tech. 2008 May; 21(3):165-74. View in: PubMed

Cervical anterior transpedicular screw fixation (ATPS)--Part II. Accuracy of manual insertion and pull-out strength of ATPS. Eur Spine J. 2008 Apr; 17(4):539-55. View in: PubMed

Biomechanical comparison of three fixation techniques for unstable thoracolumbar burst fractures. Laboratory investigation. J Neurosurg Spine. 2008 Apr; 8(4):341-6. View in: PubMed

Cervical anterior transpedicular screw fixation. Part I: Study on morphological feasibility, indications, and technical prerequisites. Eur Spine J. 2008 Apr; 17(4):523-38. View in: PubMed

Stabilization of the atlantoaxial complex via C-1 lateral mass and C-2 pedicle screw fixation in a multicenter clinical experience in 102 patients: modification of the Harms and Goel techniques. J Neurosurg Spine. 2008 Mar; 8(3):222-9. View in: PubMed

Comprehensive management of symptomatic and aggressive vertebral hemangiomas. Neurosurg Clin N Am. 2008 Jan; 19(1):17-29. View in: PubMed

Two-level total en bloc lumbar spondylectomy with dural resection for metastatic renal cell carcinoma. J Clin Neurosci. 2008 Jan; 15(1):70-2. View in: PubMed

Early Clinical & Radiographic Results of NFix II Posterior Dynamic Stabilization System. SAS J. 2008; 2(2):69-75. View in: PubMed

Partial spondylectomy: modification for lateralized malignant spinal column tumors of the cervical or lumbosacral spine. J Clin Neurosci. 2008 Jan; 15(1):43-8. View in: PubMed

Stand-alone anterior lumbar discectomy and fusion with plate: initial experience. Surg Neurol. 2007 Jul; 68(1):7-13; discussion 13. View in: PubMed

Operative management of adult high-grade lumbosacral spondylolisthesis. Neurosurg Clin N Am. 2007 Apr; 18(2):249-54. View in: PubMed

Corpectomy followed by the placement of instrumentation with titanium cages and recombinant human bone morphogenetic protein-2 for vertebral osteomyelitis. J Neurosurg Spine. 2007 Jan; 6(1):23-30. View in: PubMed

Successful outcome of six-level cervicothoracic corpectomy and circumferential reconstruction: case report and review of literature on multilevel cervicothoracic corpectomy. Eur Spine J. 2006 Oct; 15 Suppl 5:670-4. View in: PubMed

Recent advances: infections of the spine. Curr Infect Dis Rep. 2006 Sep; 8(5):390-3. View in: PubMed

Coblation of spinal endplates in preparation for interbody spinal fusion. J Clin Neurosci. 2006 Apr; 13(3):349-52. View in: PubMed

Expandable cylindrical cages in the cervical spine: a review of 22 cases. J Neurosurg Spine. 2006 Apr; 4(4):285-91. View in: PubMed

Risk factors of acute renal failure after liver transplantation. Kidney Int. 2006 Mar; 69(6):1073-80. View in: PubMed

Current treatment strategies and outcomes in the management of symptomatic vertebral hemangiomas. Neurosurgery. 2006 Feb; 58(2):287-95; discussion 287-95. View in: PubMed

Biomechanical analysis of a newly designed bioabsorbable anterior cervical plate. Invited submission from the joint section meeting on disorders of the spine and peripheral nerves, March 2005. J Neurosurg Spine. 2005 Dec; 3(6):465-70. View in: PubMed

Emerging directions in motion preservation spinal surgery. Neurosurg Clin N Am. 2005 Oct; 16(4):665-9, vii. View in: PubMed

Frameless stereotactic image-guided C1-C2 transarticular screw fixation for atlantoaxial instability: review of 20 patients. J Spinal Disord Tech. 2005 Oct; 18(5):385-91. View in: PubMed

Cervical disc arthroplasty: general introduction. Neurosurg Clin N Am. 2005 Oct; 16(4):603-7, vi. View in: PubMed

The Charité Artificial Disc: insertion technique. Neurosurg Clin N Am. 2005 Oct; 16(4):637-50, vii. View in: PubMed

The ProDisc artificial disc: insertion technique. Neurosurg Clin N Am. 2005 Oct; 16(4):651-6, vii. View in: PubMed

Artificial pedicle screw reconstruction of the cervical spine after lateral paramedian transpedicular approach for lesions of the ventral cervical spinal canal. Neurosurgery. 2005 Oct; 57(4 Suppl):281-5; discussion 281-5. View in: PubMed

The potential role of mesenchymal stem cell therapy for intervertebral disc degeneration: a critical overview. Neurosurg Focus. 2005 Sep 15; 19(3):E4. View in: PubMed

Use of intraoperative isocentric C-arm 3D fluoroscopy for sextant percutaneous pedicle screw placement: case report and review of the literature. Spine J. 2005 May-Jun; 5(3):339-43. View in: PubMed

Kyphoplasty-augmented short-segment pedicle screw fixation of traumatic lumbar burst fractures: initial clinical experience and literature review. Neurosurg Focus. 2005 Mar 15; 18(3):e9. View in: PubMed

Intramedullary spinal cord tumors: molecular insights and surgical innovation. Clin Neurosurg. 2005; 52:76-84. View in: PubMed

Novel treatment of basilar invagination resulting from an untreated C-1 fracture associated with transverse ligament avulsion. Case report and description of surgical technique. J Neurosurg Spine. 2005 Jan; 2(1):83-7. View in: PubMed

Neurocutaneous melanosis presenting with hydrocephalus. Case report and review of the literature. J Neurosurg. 2005 Jan; 102(1 Suppl):96-100. View in: PubMed

Diagnosis and management of adult pyogenic osteomyelitis of the cervical spine. Neurosurg Focus. 2004 Dec 15; 17(6):E2. View in: PubMed

Diagnosis and management of sacral Tarlov cysts. Case report and review of the literature. Neurosurg Focus. 2003 Aug 15; 15(2):E15. View in: PubMed

Eversion thromboendovenectomy for organized portal vein thrombosis encountered during liver transplantation. Transplant Proc. 2003 Aug; 35(5):1915-7. View in: PubMed

Does the standard vs piggyback surgical technique affect the development of early acute renal failure after orthotopic liver transplantation? Transplant Proc. Does the standard vs piggyback surgical technique affect the development of early acute renal failure after orthotopic liver transplantation? Transplant Proc. 2003 Aug; 35(5):1913-4. View in: PubMed

Treatment of intracranial glioma with in situ interferon-gamma and tumor necrosis factor-alpha gene transfer. Cancer Gene Ther. 2002 Nov; 9(11):925-34. View in: PubMed

Prognostic factors of early acute renal failure in liver transplantation. Transplant Proc. 2002 Feb; 34(1):254-5. View in: PubMed

Hepatic artery complications in a series of 300 orthotopic liver transplants. Transplant Proc. 2000 Dec; 32(8):2669-70. View in: PubMed

Incidence and survival rate of hepatic retransplantation in a series of 300 orthotopic liver transplants. Transplant Proc. 2000 Dec; 32(8):2671-2. View in: PubMed

[Neurophysiological monitoring during scoliosis surgery using controlled hypotension]. Rev Esp Anestesiol Reanim. 2000 Oct; 47(8):367-70. View in: PubMed

Liver transplantation in the management of Klatskin's tumor. Transplant Proc. 1999 Sep; 31(6):2494-5. View in: PubMed

Incidence and management of biliary tract complications following 300 consecutive orthotopic liver transplants. Transplant Proc. 1999 Sep; 31(6):2407-8. View in: PubMed

Vascular complications in a series of 300 orthotopic liver transplants. Transplant Proc. 1999 Sep; 31(6):2409-10. View in: PubMed

Is exfoliative bile cytology useful in the diagnosis of graft complications in liver transplantation? Transplant Proc. Is exfoliative bile cytology useful in the diagnosis of graft complications in liver transplantation? Transplant Proc. 1995 Aug; 27(4):2281-2. View in: PubMed

Life quality of patients undergoing liver transplantation. Transpl Int. 1994; 7 Suppl 1:S675-8. View in: PubMed

Reoperation for biliary tract complications following orthotopic liver transplantation. Br J Surg. 1993 Nov; 80(11):1426-8. View in: PubMed

[Biliary complications in the follow-up of 54 orthotopic liver transplant patients]. Rev Esp Enferm Dig. 1992 Dec; 82(6):405-10. View in: PubMed

Assessment of two measurement techniques of cervical spine and C1-C2 rotation in the outcome research of axis fractures: a morphometrical analysis using dynamic computed tomography scanning. Spine (Phila Pa 1976). 2010 Feb 01; 35(3):286-90. View in: PubMed

Biomechanics of stabilization after cervicothoracic compression-flexion injury. Spine (Phila Pa 1976). 2005 Jul 01; 30(13):1505-12. View in: PubMed

Biomechanical pullout strength and stability of the cervical artificial pedicle screw. Spine (Phila Pa 1976). 2009 Jan 01; 34(1):E16-20. View in: PubMed

Effect of age on the perioperative and radiographic complications of multilevel cervicothoracic spinal fusions. Spine (Phila Pa 1976). 2008 Dec 15; 33(26):E977-82. View in: PubMed

Biomechanics of stabilization after cervicothoracic compression-flexion injury. Spine (Phila Pa 1976). 2005 Jul 1; 30(13):1505-12. View in: PubMed

The morbidity of open transthoracic approach for anterior scoliosis correction. Spine (Phila Pa 1976). 2010 Dec 15; 35(26):E1586-92. View in: PubMed

Biomechanical comparison of posterior lumbar interbody fusion and transforaminal lumbar interbody fusion performed at 1 and 2 levels. Spine (Phila Pa 1976). 2005 Oct 01; 30(19):E562-6. View in: PubMed

Techniques for operative correction of proximal junctional kyphosis of the upper thoracic spine. Spine (Phila Pa 1976). 2012 Feb 15; 37(4):292-303. View in: PubMed

Intrathecal Morphine in Spine Surgery: A Meta-analysis of Randomized Controlled Trials. Spine (Phila Pa 1976). 2017 Jun 15; 42(12):E740-E747. View in: PubMed

Point-Counterpoint: The Use of Neuromonitoring in Lateral Transpsoas Surgery. Spine (Phila Pa 1976). 2016 Apr; 41 Suppl 8:S145-51. View in: PubMed

Human disc nucleus properties and vertebral endplate permeability. Spine (Phila Pa 1976). 2011 Apr 01; 36(7):512-20. View in: PubMed

Bioabsorbable anterior cervical plating: initial multicenter clinical and radiographic experience. Spine (Phila Pa 1976). 2007 May 01; 32(10):1084-8. View in: PubMed

Assessment of two measurement techniques of cervical spine and C1-C2 rotation in the outcome research of axis fractures: a morphometrical analysis using dynamic computed tomography scanning. Spine (Phila Pa 1976). 2010 Feb 1; 35(3):286-90. View in: PubMed

Breaking Through the "Glass Ceiling" of Minimally Invasive Spine Surgery. Spine (Phila Pa 1976). 2016 Apr; 41 Suppl 8:S39-43. View in: PubMed

Modified paramedian transpedicular approach and spinal reconstruction for intradural tumors of the cervical and cervicothoracic spine: clinical experience. Spine (Phila Pa 1976). 2007 Mar 15; 32(6):E203-10. View in: PubMed

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