Faculty

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Gere S Dizerega, MD
Professor of Research Obstetrics & Gynecology
Obstetrics & Gynecology
LRB 110 Off Campus Los Angeles
+1 323 226 4965

Overview

Dr. diZerega continues to perform research in the area of etiology of pelvic adhesions and prevention of pelvic adhesions following surgical procedures in the female pelvis. In 2000-2001 Dr. diZerega performed research to determine the efficacy of a new agent to prevent adhesions after surgical procedures in the female pelvis. Efficacy and safety of 4% 120 dextran solution was studies in 20 subjects.

Publications

Rodgers KE, Tan A, Kim L, Espinoza T, Meeks C, Johnston W, Maulhardt H, Donald M, Hill C, diZerega GS. Development of a guinea pig cutaneous radiation injury model using low penetrating X-rays. Int J Radiat Biol. 2016 Aug; 92(8):434-43. View in: PubMed

Lei W, Ehmsen RJ, Chiacchierini RP, Krelle JL, diZerega GS. Reduction of Leg Pain by Oxiplex Gel After Lumbar Discectomy in Patients With Predominant Leg Pain and Elevated Levels of Lower Back Pain: A Prospective, Randomized, Blinded, Multicenter Clinical Study. J Spinal Disord Tech. 2015 Oct; 28(8):301-7. View in: PubMed

Jadhav SS, Meeks CJ, Mordwinkin NM, Espinoza TB, Louie SG, diZerega GS, Rodgers KE. Effect of combined radiation injury on cell death and inflammation in skin. Apoptosis. 2015 Jul; 20(7):892-906. View in: PubMed

Rodgers KE, Bolton LL, Verco S, diZerega GS. NorLeu(3)-Angiotensin (1-7) [DSC127] as a Therapy for the Healing of Diabetic Foot Ulcers. Adv Wound Care (New Rochelle). 2015 Jun 01; 4(6):339-345. View in: PubMed

Williamson SK, Johnson GA, Maulhardt HA, Moore KM, McMeekin DS, Schulz TK, Reed GA, Roby KF, Mackay CB, Smith HJ, Weir SJ, Wick JA, Markman M, diZerega GS, Baltezor MJ, Espinosa J, Decedue CJ. A phase I study of intraperitoneal nanoparticulate paclitaxel (Nanotax(®)) in patients with peritoneal malignancies. Cancer Chemother Pharmacol. 2015 May; 75(5):1075-87. View in: PubMed

Rodgers KE, Peterson KJ, Maulhardt HA, Dizerega GS. Angiotensin 1 - 7 stimulation of platelet recovery. Expert Opin Investig Drugs. 2014 Apr; 23(4):551-9. View in: PubMed

Rodgers KE, Espinoza TB, Roda N, Meeks CJ, Dizerega GS. Angiotensin-(1-7) synergizes with colony-stimulating factors in hematopoietic recovery. Cancer Chemother Pharmacol. 2013 Dec; 72(6):1235-45. View in: PubMed

Pham H, Schwartz BM, Delmore JE, Reed E, Cruickshank S, Drummond L, Rodgers KE, Peterson KJ, diZerega GS. Pharmacodynamic stimulation of thrombogenesis by angiotensin (1-7) in recurrent ovarian cancer patients receiving gemcitabine and platinum-based chemotherapy. Cancer Chemother Pharmacol. 2013 Apr; 71(4):965-72. View in: PubMed

Rodgers KE, Dizerega GS. Contribution of the Local RAS to Hematopoietic Function: A Novel Therapeutic Target. Front Endocrinol (Lausanne). 2013; 4:157. View in: PubMed

Jadhav SS, Sharma N, Meeks CJ, Mordwinkin NM, Espinoza TB, Roda NR, DiZerega GS, Hill CK, Louie SG, Rodgers KE. Effects of combined radiation and burn injury on the renin-angiotensin system. Wound Repair Regen. 2013 Jan-Feb; 21(1):131-40. View in: PubMed

Balingit PP, Armstrong DG, Reyzelman AM, Bolton L, Verco SJ, Rodgers KE, Nigh KA, Dizerega GS. NorLeu(3) -A(1-7) stimulation of diabetic foot ulcer healing: Results of a randomized, parallel-group, double-blind, placebo-controlled phase 2 clinical trial. Wound Repair Regen. 2012 Jul; 20(4):482-90. View in: PubMed

Rodgers KE, Espinoza T, Roda N, Meeks CJ, Hill C, Louie SG, Dizerega GS. Accelerated hematopoietic recovery with angiotensin-(1-7) after total body radiation. Int J Radiat Biol. 2012 Jun; 88(6):466-76. View in: PubMed

Eidenschink L, Dizerega G, Rodgers K, Bartlett M, Wells DA, Loken MR. Basal levels of CD34 positive cells in peripheral blood differ between individuals and are stable for 18 months. Cytometry B Clin Cytom. 2012 Jan; 82(1):18-25. View in: PubMed

Mordwinkin NM, Russell JR, Burke AS, Dizerega GS, Louie SG, Rodgers KE. Toxicological and toxicokinetic analysis of angiotensin (1-7) in two species. J Pharm Sci. 2012 Jan; 101(1):373-80. View in: PubMed

Rodgers K, Verco S, Bolton L, Dizerega G. Accelerated healing of diabetic wounds by NorLeu(3)-angiotensin (1-7). Expert Opin Investig Drugs. 2011 Nov; 20(11):1575-81. View in: PubMed

Cui H, Gensini M, Kataria R, Twaddle T, Zhang J, Wadsworth S, Petrilli J, Rodgers K, diZerega G, Cooper K. Reducing post-surgical adhesions utilizing a drug-enhanced device: sodium carboxymethylcellulose aqueous gel/poly(p-dioxanone) and Tranilast. Biomed Mater. 2009 Feb; 4(1):015001. View in: PubMed

diZerega GS, Tulandi T. Prevention of intra-abdominal adhesions in gynaecological surgery. Reprod Biomed Online. 2008 Sep; 17(3):303-6. View in: PubMed

Petrilli J, Wadsworth S, Cooper K, Rodgers KE, Siekierka J, diZerega GS. Tranilast: a pharmaceutical candidate for reduction of adhesions using a novel approach. Semin Reprod Med. 2008 Jul; 26(4):341-8. View in: PubMed

Brown CB, Luciano AA, Martin D, Peers E, Scrimgeour A, diZerega GS. Adept (icodextrin 4% solution) reduces adhesions after laparoscopic surgery for adhesiolysis: a double-blind, randomized, controlled study. Fertil Steril. 2007 Nov; 88(5):1413-26. View in: PubMed

Cooper K, Young J, Wadsworth S, Cui H, diZerega GS, Rodgers KE. Reduction of post-surgical adhesion formation with tranilast. J Surg Res. 2007 Aug; 141(2):153-61. View in: PubMed

diZerega GS, Cortese S, Rodgers KE, Block KM, Falcone SJ, Juarez TG, Berg R. A modern biomaterial for adhesion prevention. J Biomed Mater Res B Appl Biomater. 2007 Apr; 81(1):239-50. View in: PubMed

diZerega GS, Coad J, Donnez J. Clinical evaluation of endometriosis and differential response to surgical therapy with and without application of Oxiplex/AP* adhesion barrier gel. Fertil Steril. 2007 Mar; 87(3):485-9. View in: PubMed

Bendebba M, Dizerega GS, Long DM. The Lumbar Spine Outcomes Questionnaire: its development and psychometric properties. Spine J. 2007 Jan-Feb; 7(1):118-32. View in: PubMed

Rodgers KE, Oliver J, diZerega GS. Phase I/II dose escalation study of angiotensin 1-7 [A(1-7)] administered before and after chemotherapy in patients with newly diagnosed breast cancer. Cancer Chemother Pharmacol. 2006 May; 57(5):559-68. View in: PubMed

Rodgers KE, Ellefson DD, Espinoza T, Hsu YH, diZerega GS, Mehrian-Shai R. Expression of intracellular filament, collagen, and collagenase genes in diabetic and normal skin after injury. Wound Repair Regen. 2006 May-Jun; 14(3):298-305. View in: PubMed

Young P, Johns A, Templeman C, Witz C, Webster B, Ferland R, Diamond MP, Block K, diZerega G. Reduction of postoperative adhesions after laparoscopic gynecological surgery with Oxiplex/AP Gel: a pilot study. Fertil Steril. 2005 Nov; 84(5):1450-6. View in: PubMed

Rodgers KE, Ellefson DD, Espinoza T, Roda N, Maldonado S, Dizerega GS. Effect of NorLeu3-A(1-7) on scar formation over time after full-thickness incision injury in the rat. Wound Repair Regen. 2005 May-Jun; 13(3):309-17. View in: PubMed

Kim KD, Wang JC, Robertson DP, Brodke DS, BenDebba M, Block KM, diZerega GS. Reduction of leg pain and lower-extremity weakness for 1 year with Oxiplex/SP gel following laminectomy, laminotomy, and discectomy. Neurosurg Focus. 2004 Jul 15; 17(1):ECP1. View in: PubMed

Ellefson DD, diZerega GS, Espinoza T, Roda N, Maldonado S, Rodgers KE. Synergistic effects of co-administration of angiotensin 1-7 and Neupogen on hematopoietic recovery in mice. Cancer Chemother Pharmacol. 2004 Jan; 53(1):15-24. View in: PubMed

Rodgers KE, Roda N, Felix JE, Espinoza T, Maldonado S, diZerega G. Histological evaluation of the effects of angiotensin peptides on wound repair in diabetic mice. Exp Dermatol. 2003 Dec; 12(6):784-90. View in: PubMed

Rodgers KE, Robertson JT, Espinoza T, Oppelt W, Cortese S, diZerega GS, Berg RA. Reduction of epidural fibrosis in lumbar surgery with Oxiplex adhesion barriers of carboxymethylcellulose and polyethylene oxide. Spine J. 2003 Jul-Aug; 3(4):277-83; discussion 284. View in: PubMed

Rodgers KE, Espinoza T, Felix J, Roda N, Maldonado S, diZerega G. Acceleration of healing, reduction of fibrotic scar, and normalization of tissue architecture by an angiotensin analogue, NorLeu3-A(1-7). Plast Reconstr Surg. 2003 Mar; 111(3):1195-206. View in: PubMed

Rodgers K, Xiong S, DiZerega GS. Effect of angiotensin II and angiotensin(1-7) on hematopoietic recovery after intravenous chemotherapy. Cancer Chemother Pharmacol. 2003 Feb; 51(2):97-106. View in: PubMed

Rodgers KE, Xiong S, diZerega GS. Accelerated recovery from irradiation injury by angiotensin peptides. Cancer Chemother Pharmacol. 2002 May; 49(5):403-11. View in: PubMed

Rhyne AL, Blumenthal SL, Frank EH, Hsu KY, Kim KD, Youssef JA, Wang JC, Arnold P, BenDebba M, Block KM, Juarez TG, Chiacchierini RP, Ehmsen RJ, Krelle JS, diZerega GS. Oxiplex reduces leg pain, back pain, and associated symptoms after lumbar discectomy. Spine (Phila Pa 1976). 2012 Apr 15; 37(8):631-41. View in: PubMed

Kim KD, Wang JC, Robertson DP, Brodke DS, Olson EM, Duberg AC, BenDebba M, Block KM, diZerega GS. Reduction of radiculopathy and pain with Oxiplex/SP gel after laminectomy, laminotomy, and discectomy: a pilot clinical study. Spine (Phila Pa 1976). 2003 May 15; 28(10):1080-7; discussion 1087-8. View in: PubMed

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