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Hiroyuki Shimada, MD, PhD
Professor of Pathology (Clinical Scholar)
CHL Mail Stop 43 Off Campus Los Angeles
+1 323 361 5813


University of Chicago: Eleanor Humphreys Visiting Professorship, 2005

Society for Pediatric Pathology: Lotte Strauss Prize, 1989


Effects of Mild Cognitive Impairment on the Development of Fear of Falling in Older Adults: A Prospective Cohort Study. J Am Med Dir Assoc. 2015 Dec 1; 16(12):1104. e9-1104. e13. View in: PubMed

Social Frailty in Community-Dwelling Older Adults as a Risk Factor for Disability. J Am Med Dir Assoc. 2015 Nov 1; 16(11):1003. e7-1003. e11. View in: PubMed

Association of Social Frailty With Both Cognitive and Physical Deficits Among Older People. J Am Med Dir Assoc. 2017 Apr 11. View in: PubMed

Effects of Cognitive Leisure Activity on Cognition in Mild Cognitive Impairment: Results of a Randomized Controlled Trial. J Am Med Dir Assoc. 2017 Apr 07. View in: PubMed

Postoperative roll cake-like macular fold after retinal detachment surgery. Int Ophthalmol. 2017 Apr 03. View in: PubMed

Severe hypertriglyceridemia during treatment of acute lymphoblastic leukemia associated with type III hyperlipoproteinemia. Pediatr Blood Cancer. 2017 Apr 01. View in: PubMed

Vitamin D receptor gene polymorphisms, smoking, and risk of sporadic Parkinson's disease in Japan. Neurosci Lett. 2017 Mar 16; 643:97-102. View in: PubMed

Reduced anterior chamber contamination by frequent surface irrigation with diluted iodine solutions during cataract surgery. Acta Ophthalmol. 2017 Mar 08. View in: PubMed

The association between anorexia of aging and physical frailty: Results from the national center for geriatrics and gerontology's study of geriatric syndromes. Maturitas. 2017 Mar; 97:32-37. View in: PubMed

Impact of poor sleep quality and physical inactivity on cognitive function in community-dwelling older adults. Geriatr Gerontol Int. 2017 Feb 11. View in: PubMed

Brain uptake and safety of Flutemetamol F 18 injection in Japanese subjects with probable Alzheimer's disease, subjects with amnestic mild cognitive impairment and healthy volunteers. Ann Nucl Med. 2017 Feb 08. View in: PubMed

Randomized double-blind placebo-controlled multicenter trial of Yokukansan for neuropsychiatric symptoms in Alzheimer's disease. Geriatr Gerontol Int. 2017 Feb; 17(2):211-218. View in: PubMed

Prospective associations between sedentary behaviour and incident depressive symptoms in older people: a 15-month longitudinal cohort study. Int J Geriatr Psychiatry. 2017 Feb; 32(2):193-200. View in: PubMed

Salvage therapy for children with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia. Pediatr Blood Cancer. 2017 Jan 13. View in: PubMed

Subjective Memory Complaints are Associated with Incident Dementia in Cognitively Intact Older People, but Not in Those with Cognitive Impairment: A 24-Month Prospective Cohort Study. Am J Geriatr Psychiatry. 2017 Jan 04. View in: PubMed

Relationship Between Frailty and Oral Function in Community-Dwelling Elderly Adults. J Am Geriatr Soc. 2017 Jan; 65(1):66-76. View in: PubMed

The Associations among Insulin Resistance, Hyperglycemia, Physical Performance, Diabetes Mellitus, and Cognitive Function in Relatively Healthy Older Adults with Subtle Cognitive Dysfunction. Front Aging Neurosci. 2017; 9:72. View in: PubMed

Recommendations for the standardization of bone marrow disease assessment and reporting in children with neuroblastoma; on behalf of the International Neuroblastoma Response Criteria Bone Marrow Working Group. Cancer. 2016 Dec 16. View in: PubMed

Prevention and treatment of postoperative endophthalmitis using povidone-iodine. Curr Pharm Des. 2016 Dec 04. View in: PubMed

Cancer association as a risk factor for anti-HMGCR antibody-positive myopathy. Neurol Neuroimmunol Neuroinflamm. 2016 Dec; 3(6):e290. View in: PubMed

Age-related changes in prefrontal oxygenation during memory encoding and retrieval. Geriatr Gerontol Int. 2016 Dec; 16(12):1296-1304. View in: PubMed

Association of high microvessel avß3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126. Oncotarget. 2016 Nov 16. View in: PubMed

Prevalence of frailty in Japan: A systematic review and meta-analysis. J Epidemiol. 2016 Nov 15. View in: PubMed

Implantable chemotherapy-loaded silk protein materials for neuroblastoma treatment. Int J Cancer. 2016 Oct 22. View in: PubMed

Comorbid Mild Cognitive Impairment and Depressive Symptoms Predict Future Dementia in Community Older Adults: A 24-Month Follow-Up Longitudinal Study. J Alzheimers Dis. 2016 Oct 18; 54(4):1473-1482. View in: PubMed

Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection and mortality. EMBO Mol Med. 2016 Oct 13. View in: PubMed


Relationship between chronic kidney disease with diabetes or hypertension and frailty in community-dwelling Japanese older adults. Geriatr Gerontol Int. 2016 Sep 27. View in: PubMed

Objectively-measured outdoor time and physical and psychological function among older adults. Geriatr Gerontol Int. 2016 Sep 16. View in: PubMed

Joint Association of Neighborhood Environment and Fear of Falling on Physical Activity Among Frail Older Adults. J Aging Phys Act. 2016 Sep 6; 1-28. View in: PubMed

Serum Levels of Albumin-ß-Amyloid Complex in Patients with Depression. Am J Geriatr Psychiatry. 2016 Sep; 24(9):764-72. View in: PubMed

Effects of group exercise programmes on quality of life in older adults with mild cognitive impairment: preliminary results from a randomized controlled trial. Psychogeriatrics. 2016 Sep; 16(5):327-8. View in: PubMed

Reactive Oxygen Species Mediates the Synergistic Activity of Fenretinide Combined with the Microtubule Inhibitor ABT-751 against Multidrug-Resistant Recurrent Neuroblastoma Xenografts. Mol Cancer Ther. 2016 Aug 16. View in: PubMed

Sleep Duration and Excessive Daytime Sleepiness Are Associated With Incidence of Disability in Community-Dwelling Older Adults. J Am Med Dir Assoc. 2016 Aug 1; 17(8):768. e1-5. View in: PubMed

A Phase I New Approaches to Neuroblastoma Therapy Study of Buthionine Sulfoximine and Melphalan With Autologous Stem Cells for Recurrent/Refractory High-Risk Neuroblastoma. Pediatr Blood Cancer. 2016 Aug; 63(8):1349-56. View in: PubMed

Anti-TIF1-? antibody and cancer-associated myositis: A clinicohistopathologic study. Neurology. 2016 Jul 19; 87(3):299-308. View in: PubMed

Psychological predictors of participation in screening for cognitive impairment among community-dwelling older adults. Geriatr Gerontol Int. 2016 Jul 18. View in: PubMed

Gray matter volume and dual-task gait performance in mild cognitive impairment. Brain Imaging Behav. 2016 Jul 09. View in: PubMed

The clinical management and outcomes of cervical neuroblastic tumors. J Surg Res. 2016 Jul; 204(1):109-13. View in: PubMed

[Exercise and Physical Activity for Dementia Prevention]. Brain Nerve. 2016 Jul; 68(7):799-808. View in: PubMed

Association between sedentary time and kidney function in community-dwelling elderly Japanese people. Geriatr Gerontol Int. 2016 Jun 14. View in: PubMed

Intravitreal Tissue Plasminogen Activator, Ranibizumab, and Gas Injection for Submacular Hemorrhage in Polypoidal Choroidal Vasculopathy. Ophthalmology. 2016 Jun; 123(6):1278-86. View in: PubMed

Reduced prefrontal oxygenation in mild cognitive impairment during memory retrieval. Int J Geriatr Psychiatry. 2016 Jun; 31(6):583-91. View in: PubMed

Insulin-Like Growth Factor-1 Related to Disability Among Older Adults. J Gerontol A Biol Sci Med Sci. 2016 Jun; 71(6):797-802. View in: PubMed

Importance of Phox2B Immunohistochemical Stain for Detecting Metastatic Neuroblastoma Cells in Bone Marrow Specimens. Pediatr Dev Pathol. 2016 May-Jun; 19(3):254-5. View in: PubMed

Self-reported exhaustion associated with physical activity among older adults. Geriatr Gerontol Int. 2016 May; 16(5):625-30. View in: PubMed

Phase I Study of the Aurora A Kinase Inhibitor Alisertib in Combination With Irinotecan and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma: A NANT (New Approaches to Neuroblastoma Therapy) Trial. J Clin Oncol. 2016 Apr 20; 34(12):1368-75. View in: PubMed

Driving continuity in cognitively impaired older drivers. Geriatr Gerontol Int. 2016 Apr; 16(4):508-14. View in: PubMed

PARK16 polymorphisms, interaction with smoking, and sporadic Parkinson's disease in Japan. J Neurol Sci. 2016 Mar 15; 362:47-52. View in: PubMed

Leukostasis in Children and Adolescents with Chronic Myeloid Leukemia: Japanese Pediatric Leukemia/Lymphoma Study Group. Pediatr Blood Cancer. 2016 Mar; 63(3):406-11. View in: PubMed

[Significance and progress of DIAN/A4/API]. Nihon Rinsho. 2016 Mar; 74(3):417-22. View in: PubMed

Performance on the flanker task predicts driving cessation in older adults. Int J Geriatr Psychiatry. 2016 Feb; 31(2):169-75. View in: PubMed

Combined Effect of Slow Gait Speed and Depressive Symptoms on Incident Disability in Older Adults. J Am Med Dir Assoc. 2016 Feb 1; 17(2):123-7. View in: PubMed

Driving and Incidence of Functional Limitation in Older People: A Prospective Population-Based Study. Gerontology. 2016; 62(6):636-643. View in: PubMed

Characteristics of Hyperautofluorescent Choroidal Vessels Using Fundus Camera Type Short-Wavelength Autofluorescence. Ophthalmologica. 2016; 236(3):175-180. View in: PubMed

Going outdoors and cognitive function among community-dwelling older adults: Moderating role of physical function. Geriatr Gerontol Int. 2016 Jan; 16(1):65-73. View in: PubMed

Cognitive Impairment and Disability in Older Japanese Adults. PLoS One. 2016; 11(7):e0158720. View in: PubMed

The effects of the employment of physical therapists and occupational therapists on the gait function of adult day service users after 1 year. Nihon Ronen Igakkai Zasshi. 2016; 53(4):412-418. View in: PubMed

Motoric Cognitive Risk Syndrome: Prevalence and Risk Factors in Japanese Seniors. J Am Med Dir Assoc. 2015 Dec 1; 16(12):1103. e21-5. View in: PubMed

Mild Cognitive Impairment, Slow Gait, and Risk of Disability: A Prospective Study. J Am Med Dir Assoc. 2015 Dec 1; 16(12):1082-6. View in: PubMed

Effects of white matter lesions on trunk stability during dual-task walking among older adults with mild cognitive impairment. Age (Dordr). 2015 Dec; 37(6):120. View in: PubMed

The 14-3-3 gene function of Cryptococcus neoformans is required for its growth and virulence. J Microbiol Biotechnol. 2015 Oct 6. View in: PubMed

Set-Shifting Ability Is Associated with Gray Matter Volume in Older People with Mild Cognitive Impairment. Dement Geriatr Cogn Dis Extra. 2015 Sep-Dec; 5(3):395-403. View in: PubMed

Onset of Disability According to Mild Cognitive Impairment Subtype in Community-Dwelling Older Adults in Japan. J Am Geriatr Soc. 2015 Sep; 63(9):1959-61. View in: PubMed


Subjective physical and cognitive age among community-dwelling older people aged 75 years and older: differences with chronological age and its associated factors. Aging Ment Health. 2015 Aug; 19(8):756-61. View in: PubMed

Cognitive function and falling among older adults with mild cognitive impairment and slow gait. Geriatr Gerontol Int. 2015 Aug; 15(8):1073-8. View in: PubMed

Incidence of Disability in Frail Older Persons With or Without Slow Walking Speed. J Am Med Dir Assoc. 2015 Aug 1; 16(8):690-6. View in: PubMed

Insulin-like Growth Factor 2 Gene Expression Molecularly Differentiates Pleuropulmonary Blastoma and Embryonal Rhabdomyosarcoma. J Pediatr Hematol Oncol. 2015 Aug; 37(6):e356-60. View in: PubMed

Exosome-Mediated Transfer of microRNAs Within the Tumor Microenvironment and Neuroblastoma Resistance to Chemotherapy. J Natl Cancer Inst. 2015 Jul; 107(7). View in: PubMed

Phase I Study of Vorinostat as a Radiation Sensitizer with 131I-Metaiodobenzylguanidine (131I-MIBG) for Patients with Relapsed or Refractory Neuroblastoma. Clin Cancer Res. 2015 Jun 15; 21(12):2715-21. View in: PubMed

[Incidence of Postoperative Retinal Detachment after 25-gauge Vitrectomy for Macular Diseases]. Nihon Ganka Gakkai Zasshi. 2015 Jun; 119(6):402-9. View in: PubMed

Vitrectomy using 0. 025% povidone-iodine in balanced salt solution plus for the treatment of postoperative endophthalmitis. Retina. 2015 Jun; 35(6):1087-94. View in: PubMed

Nitrogen K-edge x-ray absorption near edge structure of pyrimidine-containing nucleotides in aqueous solution. J Chem Phys. 2015 May 7; 142(17):175102. View in: PubMed

Cigarette smoking and cognitive health in elderly Japanese. Am J Health Behav. 2015 May; 39(3):294-300. View in: PubMed

Imatinib use immediately before stem cell transplantation in children with Philadelphia chromosome-positive acute lymphoblastic leukemia: Results from Japanese Pediatric Leukemia/Lymphoma Study Group (JPLSG) Study Ph(+) ALL04. Cancer Med. 2015 May; 4(5):682-9. View in: PubMed

Human and mouse tissue-engineered small intestine both demonstrate digestive and absorptive function. Am J Physiol Gastrointest Liver Physiol. 2015 Apr 15; 308(8):G664-77. View in: PubMed

The Association Between Kidney Function and Cognitive Decline in Community-Dwelling, Elderly Japanese People. J Am Med Dir Assoc. 2015 Apr 1; 16(4):349. e1-5. View in: PubMed

Apolipoprotein?E genotype and physical function among older people with mild cognitive impairment. Geriatr Gerontol Int. 2015 Apr; 15(4):422-7. View in: PubMed

Moderate-intensity physical activity, hippocampal volume, and memory in older adults with mild cognitive impairment. J Gerontol A Biol Sci Med Sci. 2015 Apr; 70(4):480-6. View in: PubMed

(131)I-Metaiodobenzylguanidine with Intensive Chemotherapy and Autologous Stem Cell Transplantation for High-Risk Neuroblastoma. A New Approaches to Neuroblastoma Therapy (NANT) Phase II Study. Biol Blood Marrow Transplant. 2015 Apr; 21(4):673-81. View in: PubMed

Physical frailty predicts incident depressive symptoms in elderly people: prospective findings from the obu study of health promotion for the elderly. J Am Med Dir Assoc. 2015 Mar; 16(3):194-9. View in: PubMed

Successful treatment of metastatic rhabdomyosarcoma with radiochemotherapy and allogeneic hematopoietic stem cell transplantation. Jpn J Clin Oncol. 2015 Feb; 45(2):225-8. View in: PubMed

Association of insulin-like growth factor-1 with mild cognitive impairment and slow gait speed. Neurobiol Aging. 2015 Feb; 36(2):942-7. View in: PubMed

Objectively measured physical activity, brain atrophy, and white matter lesions in older adults with mild cognitive impairment. Exp Gerontol. 2015 Feb; 62:1-6. View in: PubMed

Effects of exercise and horticultural intervention on the brain and mental health in older adults with depressive symptoms and memory problems: study protocol for a randomized controlled trial [UMIN000018547]. Trials. 2015; 16(1):499. View in: PubMed

Impact of physical frailty on disability in community-dwelling older adults: a prospective cohort study. BMJ Open. 2015; 5(9):e008462. View in: PubMed

A Second Pedigree with Amyloid-less Familial Alzheimer's Disease Harboring an Identical Mutation in the Amyloid Precursor Protein Gene (E693delta). Intern Med. 2015; 54(2):205-8. View in: PubMed

Development of the Japan Science and Technology Agency Index of Competence to Assess Functional Capacity in Older Adults: Conceptual Definitions and Preliminary Items. Gerontol Geriatr Med. 2015 Jan-Dec; 1:2333721415609490. View in: PubMed

Lifestyle-Related Factors Contributing to Decline in Knee Extension Strength among Elderly Women: A Cross-Sectional and Longitudinal Cohort Study. PLoS One. 2015; 10(7):e0132523. View in: PubMed

Cognitive functioning and walking speed in older adults as predictors of limitations in self-reported instrumental activity of daily living: prospective findings from the obu study of health promotion for the elderly. Int J Environ Res Public Health. 2015; 12(3):3002-13. View in: PubMed

Incidence and predictors of sarcopenia onset in community-dwelling elderly Japanese women: 4-year follow-up study. J Am Med Dir Assoc. 2015 Jan 1; 16(1):85. e1-8. View in: PubMed

Cerebral infarction in the left hemisphere compared with the right hemisphere increases the risk of aspiration pneumonia. Osaka City Med J. 2014 Dec; 60(2):81-6. View in: PubMed

Self-reported Exhaustion is Associated with Small Life Space in Older Adults with Mild Cognitive Impairment. J Phys Ther Sci. 2014 Dec; 26(12):1979-83. View in: PubMed

Kiss1 neurons drastically change their firing activity in accordance with the reproductive state: insights from a seasonal breeder. Endocrinology. 2014 Dec; 155(12):4868-80. View in: PubMed

Age-Dependent Prognostic Effect by Mitosis-Karyorrhexis Index in Neuroblastoma: A Report from the Children's Oncology Group. Pediatr Dev Pathol. 2014 Nov-Dec; 17(6):441-9. View in: PubMed

MYCN-Dependent Expression of Sulfatase-2 Regulates Neuroblastoma Cell Survival. Cancer Res. 2014 Nov 1; 74(21):5999-6009. View in: PubMed

Depressive symptoms and cognitive performance in older adults. J Psychiatr Res. 2014 Oct; 57:149-56. View in: PubMed

Development of an equation for estimating appendicular skeletal muscle mass in Japanese older adults using bioelectrical impedance analysis. Geriatr Gerontol Int. 2014 Oct; 14(4):851-7. View in: PubMed

Depressive symptoms in older adults are associated with decreased cerebral oxygenation of the prefrontal cortex during a trail-making test. Arch Gerontol Geriatr. 2014 Sep-Oct; 59(2):422-8. View in: PubMed

Diffusion-weighted imaging thermometry in multiple sclerosis. J Magn Reson Imaging. 2014 Sep; 40(3):649-54. View in: PubMed

Nitrogen K-edge X-ray absorption near edge structure (XANES) spectra of purine-containing nucleotides in aqueous solution. J Chem Phys. 2014 Aug 7; 141(5):055102. View in: PubMed

Acquisition process of typing skill using hierarchical materials in the Japanese language. Atten Percept Psychophys. 2014 Aug; 76(6):1838-46. View in: PubMed

Secondary malignant neoplasms after high-dose chemotherapy and autologous stem cell rescue for high-risk neuroblastoma. Pediatr Blood Cancer. 2014 Aug; 61(8):1350-6. View in: PubMed

Serum levels of albumin-amyloid beta complexes are decreased in Alzheimer's disease. Geriatr Gerontol Int. 2014 Jul; 14(3):716-23. View in: PubMed

Association of knee-extension strength with instrumental activities of daily living in community-dwelling older adults. Geriatr Gerontol Int. 2014 Jul; 14(3):674-80. View in: PubMed

The cultural background of the non-academic concept of psychology in Japan: Its implications for introductory education in psychology. Int J Psychol. 2014 Jun; 49(3):167-74. View in: PubMed

Effects of mild and global cognitive impairment on the prevalence of fear of falling in community-dwelling older adults. Maturitas. 2014 May; 78(1):62-6. View in: PubMed

The combined status of physical performance and depressive symptoms is strongly associated with a history of falling in community-dwelling elderly: Cross-sectional findings from the Obu Study of Health Promotion for the Elderly (OSHPE). Arch Gerontol Geriatr. 2014 May-Jun; 58(3):327-31. View in: PubMed

A case of anti-N-methyl-d-aspartate receptor encephalitis with multiple sclerosis-like demyelinated lesions. Mult Scler Relat Disord. 2014 May; 3(3):391-7. View in: PubMed

Immunosuppressive therapy with horse anti-thymocyte globulin and cyclosporine as treatment for fulminant aplastic anemia in children. Ann Hematol. 2014 May; 93(5):747-52. View in: PubMed

Validation of a prognostic multi-gene signature in high-risk neuroblastoma using the high throughput digital NanoString nCounter™ system. Mol Oncol. 2014 May; 8(3):669-78. View in: PubMed

Metastatic Neuroblastoma Confined to Distant Lymph Nodes (stage 4N) Predicts Outcome in Patients With Stage 4 Disease: A Study From the International Neuroblastoma Risk Group Database. J Clin Oncol. 2014 Apr 20; 32(12):1228-35. View in: PubMed

Prophylaxis for acute scleral buckle infection using 0. 25 % povidone-iodine ocular surface irrigation during surgery. Int Ophthalmol. 2014 Apr; 34(2):211-6. View in: PubMed

Two cases of neuroblastoma comprising two distinct clones. Pediatr Blood Cancer. 2014 Apr; 61(4):760-2. View in: PubMed

Hospitalists should have increased suspicion for primary ciliary dyskinesia in patients with congenital heart disease. Hosp Pediatr. 2014 Mar; 4(2):109-12. View in: PubMed

Neuroblastoma or not neuroblastoma. Hum Pathol. 2014 Mar; 45(3):662-3. View in: PubMed

Using two different algorithms to determine the prevalence of sarcopenia. Geriatr Gerontol Int. 2014 Feb; 14 Suppl 1:46-51. View in: PubMed

A large, cross-sectional observational study of serum BDNF, cognitive function, and mild cognitive impairment in the elderly. Front Aging Neurosci. 2014; 6:69. View in: PubMed

Basic setup and disinfection. Dev Ophthalmol. 2014; 54:63-70. View in: PubMed

Factors associated with the level of disability in elderly adults based on the Japanese long-term care insurance system. Nihon Ronen Igakkai Zasshi. 2014; 51(1):69-73. View in: PubMed

Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion. Int J Hematol. 2014 Jan; 99(1):21-31. View in: PubMed

Cognitive function and gait speed under normal and dual-task walking among older adults with mild cognitive impairment. BMC Neurol. 2014; 14(1):67. View in: PubMed

What skilled typists don't know about the QWERTY keyboard. Atten Percept Psychophys. 2014 Jan; 76(1):162-71. View in: PubMed

Significance of CD66c expression in childhood acute lymphoblastic leukemia. Leuk Res. 2014 Jan; 38(1):42-8. View in: PubMed

Olfactory identification and cognitive performance in community-dwelling older adults with mild cognitive impairment. Chem Senses. 2014 Jan; 39(1):39-46. View in: PubMed

Management of Stage 4S Composite Neuroblastoma With a MYCN-amplified Nodule. J Pediatr Hematol Oncol. 2014 Jan; 36(1):e31-5. View in: PubMed

Phase I trial of fenretinide delivered orally in a novel organized lipid complex in patients with relapsed/refractory neuroblastoma: a report from the New Approaches to Neuroblastoma Therapy (NANT) consortium. Pediatr Blood Cancer. 2013 Nov; 60(11):1801-8. View in: PubMed

Neuroblastoma of undifferentiated subtype, prognostic significance of prominent nucleolar formation, and MYC/MYCN protein expression: a report from the Children's Oncology Group. Cancer. 2013 Oct 15; 119(20):3718-26. View in: PubMed

Brain activation during dual-task walking and executive function among older adults with mild cognitive impairment: a fNIRS study. Aging Clin Exp Res. 2013 Oct; 25(5):539-44. View in: PubMed

[The DIAN Study]. Brain Nerve. 2013 Oct; 65(10):1179-84. View in: PubMed

Evaluation of multidimensional neurocognitive function using a tablet personal computer: test-retest reliability and validity in community-dwelling older adults. Geriatr Gerontol Int. 2013 Oct; 13(4):860-6. View in: PubMed

The lost intrinsic fragmentation of MAT1 protein during granulopoiesis promotes the growth and metastasis of leukemic myeloblasts. Stem Cells. 2013 Sep; 31(9):1942-53. View in: PubMed

Nonsense mutation in HLA-B*40:02 in a case with acquired aplastic anaemia: a possible origin of clonal escape from autoimmune insult. Br J Haematol. 2013 Sep; 162(5):706-7. View in: PubMed

Minimizing the endophthalmitis rate following intravitreal injections using 0. 25% povidone-iodine irrigation and surgical mask. Graefes Arch Clin Exp Ophthalmol. 2013 Aug; 251(8):1885-90. View in: PubMed

Critical role of STAT3 in IL-6-mediated drug resistance in human neuroblastoma. Cancer Res. 2013 Jul 1; 73(13):3852-64. View in: PubMed

Demonstration of novel gain-of-function mutations of aIIbß3: association with macrothrombocytopenia and glanzmann thrombasthenia-like phenotype. Mol Genet Genomic Med. 2013 Jul; 1(2):77-86. View in: PubMed

Combined prevalence of frailty and mild cognitive impairment in a population of elderly Japanese people. J Am Med Dir Assoc. 2013 Jul; 14(7):518-24. View in: PubMed

Large congenital melanocytic nevi with atypical teratoid/rhabdoid tumor. Pediatr Blood Cancer. 2013 Jul; 60(7):1240-1. View in: PubMed

Measuring indoor life-space mobility at home in older adults with difficulty to perform outdoor activities. J Geriatr Phys Ther. 2013 Jul-Sep; 36(3):109-14. View in: PubMed

Gait adaptability and brain activity during unaccustomed treadmill walking in healthy elderly females. Gait Posture. 2013 Jun; 38(2):203-8. View in: PubMed

Leukemia kidney infiltration can cause secondary polycythemia by activating hypoxia-inducible factor (HIF) pathway. Eur J Pediatr. 2013 Jun; 172(6):829-32. View in: PubMed

Transient treatment with epigenetic modifiers yields stable neuroblastoma stem cells resembling aggressive large-cell neuroblastomas. Proc Natl Acad Sci U S A. 2013 Apr 9; 110(15):6097-102. View in: PubMed

Relationship between near-infrared spectroscopy, and subcutaneous fat and muscle thickness measured by ultrasonography in Japanese community-dwelling elderly. Geriatr Gerontol Int. 2013 Apr; 13(2):351-7. View in: PubMed

Relationship between dual-task performance and neurocognitive measures in older adults with mild cognitive impairment. Geriatr Gerontol Int. 2013 Apr; 13(2):314-21. View in: PubMed

Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy. Blood. 2013 Mar 7; 121(10):1814-8. View in: PubMed

Peripheral neuroblastic tumors with genotype-phenotype discordance: a report from the Children's Oncology Group and the International Neuroblastoma Pathology Committee. Pediatr Blood Cancer. 2013 Mar; 60(3):363-70. View in: PubMed

Retinoid agonist Am80-enhanced neutrophil bactericidal activity arising from granulopoiesis in vitro and in a neutropenic mouse model. Blood. 2013 Feb 7; 121(6):996-1007. View in: PubMed

Reducing bacterial contamination inside fluid catch bag in 25-gauge vitrectomy by use of 0. 25 % povidone-iodine ocular surface irrigation. Int Ophthalmol. 2013 Feb; 33(1):35-8. View in: PubMed

Poor balance and lower gray matter volume predict falls in older adults with mild cognitive impairment. BMC Neurol. 2013; 13(1):102. View in: PubMed

Factors associated with life-space in older adults with amnestic mild cognitive impairment. Geriatr Gerontol Int. 2013 Jan; 13(1):161-6. View in: PubMed

Characteristics of cognitive function in early and late stages of amnestic mild cognitive impairment. Geriatr Gerontol Int. 2013 Jan; 13(1):83-9. View in: PubMed

Six-minute walking distance correlated with memory and brain volume in older adults with mild cognitive impairment: a voxel-based morphometry study. Dement Geriatr Cogn Dis Extra. 2013; 3(1):223-32. View in: PubMed

[Are gait parameters related to knee pain, urinary incontinence and a history of falls in community-dwelling elderly women?]. [Are gait parameters related to knee pain, urinary incontinence and a history of falls in community-dwelling elderly women? ]. Nihon Ronen Igakkai Zasshi. 2013; 50(4):528-35. View in: PubMed

A randomized controlled trial of multicomponent exercise in older adults with mild cognitive impairment. PLoS One. 2013; 8(4):e61483. View in: PubMed

Performance-based assessments and demand for personal care in older Japanese people: a cross-sectional study. BMJ Open. 2013; 3(4). View in: PubMed

Cognitive function affects trainability for physical performance in exercise intervention among older adults with mild cognitive impairment. Clin Interv Aging. 2013; 8:97-102. View in: PubMed

Forearm skeletal muscle neuroblastoma in a child: a rare primary location. J Pediatr Hematol Oncol. 2013 Jan; 35(1):61-3. View in: PubMed

Effects of multicomponent exercise on spatial-temporal gait parameters among the elderly with amnestic mild cognitive impairment (aMCI): preliminary results from a randomized controlled trial (RCT). Arch Gerontol Geriatr. 2013 Jan-Feb; 56(1):104-8. View in: PubMed

Stimulus duration and pain in nerve conduction studies. Muscle Nerve. 2013 Jan; 47(1):12-6. View in: PubMed

Relationship between going outdoors daily and activation of the prefrontal cortex during verbal fluency tasks (VFTs) among older adults: a near-infrared spectroscopy study. Arch Gerontol Geriatr. 2013 Jan-Feb; 56(1):118-23. View in: PubMed

Reduction of vitreous contamination rate after 25-gauge vitrectomy by surface irrigation with 0. 25% povidone-iodine. Retina. 2013 Jan; 33(1):143-51. View in: PubMed

MDR1 C3435T polymorphism and interaction with environmental factors in risk of Parkinson's disease: a case-control study in Japan. Drug Metab Pharmacokinet. 2013; 28(2):138-43. View in: PubMed

Cognitive activities and instrumental activity of daily living in older adults with mild cognitive impairment. Dement Geriatr Cogn Dis Extra. 2013; 3(1):398-406. View in: PubMed

Lack of association between BST1 polymorphisms and sporadic Parkinson's disease in a Japanese population. J Neurol Sci. 2012 Dec 15; 323(1-2):162-6. View in: PubMed

The germline TP53 mutation c. 722 C>T promotes bone and liver tumorigenesis at a young age. Pediatr Blood Cancer. 2012 Dec 15; 59(7):1332-3. View in: PubMed

Primary renal neuroblastoma. Am J Surg Pathol. 2012 Dec; 36(12):1904-5; author reply 1905. View in: PubMed

Does a multicomponent exercise program improve dual-task performance in amnestic mild cognitive impairment? A randomized controlled trial. Aging Clin Exp Res. 2012 Dec; 24(6):640-6. View in: PubMed

Re: Needle core vs open biopsy for diagnosis of intermediate- and high-risk neuroblastoma in children. J Pediatr Surg. 2012 Nov; 47(11):2162-3; author reply 2163-5. View in: PubMed

Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma. J Clin Oncol. 2012 Oct 1; 30(28):3525-32. View in: PubMed

Estimation of appendicular muscle mass and fat mass by near infrared spectroscopy in older persons. Geriatr Gerontol Int. 2012 Oct; 12(4):652-8. View in: PubMed

The relationship between atrophy of the medial temporal area and daily activities in older adults with mild cognitive impairment. Aging Clin Exp Res. 2012 Oct; 24(5):423-9. View in: PubMed

Safety and efficacy of linezolid in 16 infants and children in Japan. J Infect Chemother. 2012 Aug; 18(4):591-6. View in: PubMed

Derlin-1-immunopositive inclusions in patients with Alzheimer's disease. Neuroreport. 2012 Jul 11; 23(10):611-5. View in: PubMed

Dose Escalation Study of No-Carrier-Added 131I-Metaiodobenzylguanidine for Relapsed or Refractory Neuroblastoma: New Approaches to Neuroblastoma Therapy Consortium Trial. J Nucl Med. 2012 Jul; 53(7):1155-63. View in: PubMed

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Two cases of dementias with motor neuron disease evaluated by Pittsburgh compound B-positron emission tomography. Neurol Sci. 2012 Feb; 33(1):87-92. View in: PubMed

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Microdeletion del(22)(q12. 2) encompassing the facial development-associated gene, MN1 (meningioma 1) in a child with Pierre-Robin sequence (including cleft palate) and neurofibromatosis 2 (NF2): a case report and review of the literature. BMC Med Genet. 2012; 13:19. View in: PubMed

Clinical features of pittsburgh compound-B-negative dementia. Dement Geriatr Cogn Disord. 2012; 34(2):112-20. View in: PubMed

Prevention of cognitive decline. Nihon Ronen Igakkai Zasshi. 2012; 49(1):60-2. View in: PubMed

Relationship between Atrophy of the Medial Temporal Areas and Cognitive Functions in Elderly Adults with Mild Cognitive Impairment. Eur Neurol. 2012; 67(3):168-77. View in: PubMed

UCHL1 S18Y variant is a risk factor for Parkinson's disease in Japan. BMC Neurol. 2012; 12:62. View in: PubMed

Li-Fraumeni syndrome with simultaneous osteosarcoma and liver cancer: increased expression of a CD44 variant isoform after chemotherapy. BMC Cancer. 2012; 12:444. View in: PubMed

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[Predictors of interruptions to living at home in elderly people enrolled in a home visit rehabilitation service]. Nihon Ronen Igakkai Zasshi. 2012; 49(2):214-21. View in: PubMed

[Clinical characteristics of argyrophillic grain disease and senile dementia of the neurofibrillary tangle type]. Nihon Ronen Igakkai Zasshi. 2012; 49(3):281-3. View in: PubMed

The association between decline in physical functioning and atrophy of medial temporal areas in community-dwelling older adults with amnestic and nonamnestic mild cognitive impairment. Arch Phys Med Rehabil. 2011 Dec; 92(12):1992-9. View in: PubMed

Distinct impact of imatinib on growth at prepubertal and pubertal ages of children with chronic myeloid leukemia. J Pediatr. 2011 Oct; 159(4):676-81. View in: PubMed

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Physical factors underlying the association between lower walking performance and falls in older people: a structural equation model. Arch Gerontol Geriatr. 2011 Sep-Oct; 53(2):131-4. View in: PubMed

Pittsburgh compound B-negative dementia: a possibility of misdiagnosis of patients with non-alzheimer disease-type dementia as having AD. J Geriatr Psychiatry Neurol. 2011 Sep; 24(3):123-6. View in: PubMed

[A case of Churg-Strauss syndrome with subarachnoid hemorrhage and left phrenic nerve paralysis]. Nihon Kokyuki Gakkai Zasshi. 2011 Sep; 49(9):642-6. View in: PubMed

[A case of melioidosis occurring after a long-term stay in Vietnam that developed pulmonary cavitation and relapsed with multiple pulmonary nodules]. Nihon Kokyuki Gakkai Zasshi. 2011 Jun; 49(6):443-8. View in: PubMed

Relationship between whole body oxygen consumption and skeletal muscle glucose metabolism during walking in older adults: FDG PET study. Aging Clin Exp Res. 2011 Jun; 23(3):175-82. View in: PubMed

Declines in physical performance by sex and age among nondisabled community-dwelling older Japanese during a 6-year period. J Epidemiol. 2011 May 5; 21(3):176-83. View in: PubMed

Depiction of the vitreous pocket by optical coherence tomography. Int Ophthalmol. 2011 Feb; 31(1):51-3. View in: PubMed

Fatal infantile lactic acidosis and a novel homozygous mutation in the SUCLG1 gene: a mitochondrial DNA depletion disorder. Mol Genet Metab. 2011 Feb; 102(2):149-52. View in: PubMed

[Clinical features of reversed halo sign in cryptogenic organizing pneumonia]. Nihon Kokyuki Gakkai Zasshi. 2011 Feb; 49(2):75-80. View in: PubMed

Reduction of anterior chamber contamination rate after cataract surgery by intraoperative surface irrigation with 0. 25% povidone-iodine. Am J Ophthalmol. 2011 Jan; 151(1):11-17. e1. View in: PubMed

Fall and fracture of the elderly people. Nihon Ronen Igakkai Zasshi. 2011; 48(6):655-8. View in: PubMed

Clinical course of patients with familial early-onset Alzheimer's disease potentially lacking senile plaques bearing the E693? mutation in amyloid precursor protein. Dement Geriatr Cogn Disord. 2011; 32(1):45-54. View in: PubMed

Genetic polymorphisms involved in dopaminergic neurotransmission and risk for Parkinson's disease in a Japanese population. BMC Neurol. 2011; 11:89. View in: PubMed

Ewing tumors that do not overexpress BMI-1 are a distinct molecular subclass with variant biology: a report from the Children's Oncology Group. Clin Cancer Res. 2011 Jan 1; 17(1):56-66. View in: PubMed

Relationship between subjective fall risk assessment and falls and fall-related fractures in frail elderly people. BMC Geriatr. 2011; 11:40. View in: PubMed

A new infusion sustainer that stabilizes perfusion during sutureless 25-gauge vitrectomy. Int Ophthalmol. 2010 Dec; 30(6):735-8. View in: PubMed

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Association between a history of falls and the ability to multi-task in community-dwelling older people. Aging Clin Exp Res. 2010 Oct-Dec; 22(5-6):427-32. View in: PubMed

Outcome after reduced chemotherapy for intermediate-risk neuroblastoma. N Engl J Med. 2010 Sep 30; 363(14):1313-23. View in: PubMed

Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. N Engl J Med. 2010 Sep 30; 363(14):1324-34. View in: PubMed

Effect of operative field irrigation on intraoperative bacterial contamination and postoperative endophthalmitis rates in 25-gauge vitrectomy. Retina. 2010 Sep; 30(8):1242-9. View in: PubMed

Mycobacterium abscessus corneal ulcer following sutured clear corneal cataract incision. Jpn J Ophthalmol. 2010 Sep; 54(5):499-500. View in: PubMed

Neuroblastoma of unknown primary site with periorbital bone metastasis in a child. Pediatr Blood Cancer. 2010 Aug; 55(2):361-3. View in: PubMed

[Life-space of community-dwelling older adults using preventive health care services in Japan and the validity of composite scoring methods for assessment]. Nihon Koshu Eisei Zasshi. 2010 Jul; 57(7):526-37. View in: PubMed

Differences in voriconazole trough plasma concentrations per oral dosages between children younger and older than 3 years of age. Pediatr Blood Cancer. 2010 Jul 1; 54(7):1050-2. View in: PubMed

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Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children's Oncology Group. J Clin Oncol. 2010 Apr 20; 28(12):1989-94. View in: PubMed

A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo. J Neurosci. 2010 Apr 7; 30(14):4845-56. View in: PubMed

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Protein-losing enteropathy caused by gastrointestinal tract-involved Langerhans cell histiocytosis. Pediatrics. 2010 Feb; 125(2):e426-32. View in: PubMed

Outcome of 125 children with chronic myelogenous leukemia who received transplants from unrelated donors: the Japan Marrow Donor Program. Biol Blood Marrow Transplant. 2010 Feb; 16(2):231-8. View in: PubMed

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A case of multisystem Langerhans cell histiocytosis with primary hypothyroidism followed by type 1 diabetes mellitus. Pediatr Blood Cancer. 2009 Aug; 53(2):232-4. View in: PubMed

Bimanual anterior vitrectomy using a 25-gauge high-speed cutter to manage vitreous loss during phacoemulsification. Int Ophthalmol. 2009 Aug; 29(4):253-5. View in: PubMed

Double staining with brilliant blue G and double peeling for epiretinal membranes. Ophthalmology. 2009 Jul; 116(7):1370-6. View in: PubMed

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Concentration gradient of vascular endothelial growth factor in the vitreous of eyes with diabetic macular edema. Invest Ophthalmol Vis Sci. 2009 Jun; 50(6):2953-5. View in: PubMed

Combined effect of factors associated with burdens on primary caregiver. Geriatr Gerontol Int. 2009 Jun; 9(2):183-9. View in: PubMed

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Computer-aided prognosis of neuroblastoma: detection of mitosis and karyorrhexis cells in digitized histological images. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:1433-6. View in: PubMed

Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells. Cancer Res. 2009 Jan 1; 69(1):329-37. View in: PubMed

Incidence of endophthalmitis after 20- and 25-gauge vitrectomy causes and prevention. Ophthalmology. 2008 Dec; 115(12):2215-20. View in: PubMed

Clinicopathologic findings in polypoidal choroidal vasculopathy. Invest Ophthalmol Vis Sci. 2008 Nov; 49(11):4729-37. View in: PubMed

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BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression. Cancer Res. 2008 Aug 15; 68(16):6507-15. View in: PubMed

Mouse mesenchymal stem cells expressing PAX-FKHR form alveolar rhabdomyosarcomas by cooperating with secondary mutations. Cancer Res. 2008 Aug 15; 68(16):6587-97. View in: PubMed

Theoretical study of stable structures and photoelectron spectra of mass-selected Al12Cs-, Al11Cs2-, and Al10Cs3- clusters. J Chem Phys. 2008 Aug 7; 129(5):054313. View in: PubMed

Low serum 25-hydroxyvitamin D levels associated with falls among Japanese community-dwelling elderly. J Bone Miner Res. 2008 Aug; 23(8):1309-17. View in: PubMed

Frequency, source, and prevention of cotton fibers in the anterior chamber during cataract surgery. J Cataract Refract Surg. 2008 Aug; 34(8):1389-92. View in: PubMed

Identification of galectin-3-binding protein as a factor secreted by tumor cells that stimulates interleukin-6 expression in the bone marrow stroma. J Biol Chem. 2008 Jul 4; 283(27):18573-81. View in: PubMed

[Prevalence of geriatric syndrome and risk factors associated with obesity in community-dwelling elderly women]. Nihon Ronen Igakkai Zasshi. 2008 Jul; 45(4):414-20. View in: PubMed

Pathological findings of multifocal choroiditis with panuveitis and punctate inner choroidopathy. Jpn J Ophthalmol. 2008 Jul-Aug; 52(4):282-8. View in: PubMed

The comparative ability of eight functional mobility tests for predicting falls in community-dwelling older people. Age Ageing. 2008 Jul; 37(4):430-5. View in: PubMed

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A new amyloid beta variant favoring oligomerization in Alzheimer's-type dementia. Ann Neurol. 2008 Mar; 63(3):377-87. View in: PubMed

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An unusual case of neuroblastoma with angiomatoid features. J Pediatr Surg. 2007 Dec; 42(12):e11-3. View in: PubMed

The use of positron emission tomography and [18F]fluorodeoxyglucose for functional imaging of muscular activity during exercise with a stride assistance system. IEEE Trans Neural Syst Rehabil Eng. 2007 Sep; 15(3):442-8. View in: PubMed

A case of composite neuroblastoma composed of histologically and biologically distinct clones. Pediatr Dev Pathol. 2007 May-Jun; 10(3):229-32. View in: PubMed

E-cadherin cell-cell adhesion in ewing tumor cells mediates suppression of anoikis through activation of the ErbB4 tyrosine kinase. Cancer Res. 2007 Apr 1; 67(7):3094-105. View in: PubMed

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Clinicopathological findings of retinal angiomatous proliferation. Graefes Arch Clin Exp Ophthalmol. 2007 Feb; 245(2):295-300. View in: PubMed

Predictors of cessation of regular leisure-time physical activity in community-dwelling elderly people. Gerontology. 2007; 53(5):293-7. View in: PubMed

Thermal injury caused by chandelier fiber probe. Am J Ophthalmol. 2007 Jan; 143(1):167-9. View in: PubMed

Pathology of peripheral neuroblastic tumors: significance of prominent nucleoli in undifferentiated/poorly differentiated neuroblastoma. Pathol Oncol Res. 2007; 13(4):269-75. View in: PubMed

25-gauge scleral tunnel transconjunctival vitrectomy. Am J Ophthalmol. 2006 Nov; 142(5):871-3. View in: PubMed

Deferasirox and deferiprone remove cardiac iron in the iron-overloaded gerbil. Transl Res. 2006 Nov; 148(5):272-80. View in: PubMed

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Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification. J Natl Cancer Inst. 2006 Sep 6; 98(17):1193-203. View in: PubMed

Ocular complications in a child with acute graft-versus-host disease following cord blood stem cell transplantation: therapeutic challenges. Acta Ophthalmol Scand. 2006 Aug; 84(4):545-8. View in: PubMed

International neuroblastoma pathology classification adds independent prognostic information beyond the prognostic contribution of age. Eur J Cancer. 2006 May; 42(8):1113-9. View in: PubMed

Combining surgical ablation of retinal inflow and outflow vessels with photodynamic therapy for retinal angiomatous proliferation. Am J Ophthalmol. 2006 May; 141(5):968-70. View in: PubMed

Growth-chart-based qualitative evaluation of height growth after hematopoietic stem cell transplantation. Pediatr Transplant. 2006 Feb; 10(1):26-31. View in: PubMed

ABCC6 Mutation in Patients with Angioid Streaks. Int J Biomed Sci. 2006 Feb; 2(1):7-12. View in: PubMed

Effects of methylenetetrahydrofolate reductase and reduced folate carrier 1 polymorphisms on high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia or lymphoma. J Pediatr Hematol Oncol. 2006 Feb; 28(2):64-8. View in: PubMed

Image analysis for neuroblastoma classification: segmentation of cell nuclei. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:4844-7. View in: PubMed

Chromosome 1p and 11q deletions and outcome in neuroblastoma. N Engl J Med. 2005 Nov 24; 353(21):2243-53. View in: PubMed

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Mechanisms of bone invasion and metastasis in human neuroblastoma. Cancer Lett. 2005 Oct 18; 228(1-2):203-9. View in: PubMed

Favorable prognosis for patients 12 to 18 months of age with stage 4 nonamplified MYCN neuroblastoma: a Children's Cancer Group Study. J Clin Oncol. 2005 Sep 20; 23(27):6474-80. View in: PubMed

Expanded indications for 25-gauge transconjunctival vitrectomy. Jpn J Ophthalmol. 2005 Sep-Oct; 49(5):397-401. View in: PubMed

[Preoperative factors for postoperative resolution of metamorphopsia in idiopathic macular hole surgery]. Nihon Ganka Gakkai Zasshi. 2005 Sep; 109(9):591-5. View in: PubMed

Surgical excision of type 1 + 2 choroidal neovascularization in age-related macular degeneration. Jpn J Ophthalmol. 2005 Jul-Aug; 49(4):324-6. View in: PubMed

Protocol for the examination of specimens from patients with neuroblastoma and related neuroblastic tumors. Arch Pathol Lab Med. 2005 Jul; 129(7):874-83. View in: PubMed

Effects of internal limiting membrane peeling in vitrectomy on diabetic cystoid macular edema patients. Jpn J Ophthalmol. 2005 Jul-Aug; 49(4):297-300. View in: PubMed

Surgical excision of type 2 choroidal neovascularization in age-related macular degeneration. Jpn J Ophthalmol. 2005 Jul-Aug; 49(4):321-3. View in: PubMed

Endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 involves ceramide metabolic pathways. Blood. 2005 Jun 1; 105(11):4353-61. View in: PubMed

EWS-FLI1 fusion protein up-regulates critical genes in neural crest development and is responsible for the observed phenotype of Ewing's family of tumors. Cancer Res. 2005 Jun 1; 65(11):4633-44. View in: PubMed

Surgical excision of neovascularization in retinal angiomatous proliferation. Graefes Arch Clin Exp Ophthalmol. 2005 Jun; 243(6):519-24. View in: PubMed

In situ neuroblastoma: an important concept related to the natural history of neural crest tumors. Pediatr Dev Pathol. 2005 May-Jun; 8(3):305-6. View in: PubMed

Twenty-gauge Transconjunctival Vitrectomy. Jpn J Ophthalmol. 2005 May-Jun; 49(3):257-60. View in: PubMed

Neonatal gene therapy of MPS I mice by intravenous injection of a lentiviral vector. Mol Ther. 2005 May; 11(5):776-89. View in: PubMed

The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent. Cancer Res. 2005 Apr 15; 65(8):3200-8. View in: PubMed

[Evaluation of osteoporosis by markers of bone metabolism]. Nihon Naika Gakkai Zasshi. 2005 Apr 10; 94(4):675-81. View in: PubMed

Bone marrow mesenchymal stem cells provide an alternate pathway of osteoclast activation and bone destruction by cancer cells. Cancer Res. 2005 Feb 15; 65(4):1129-35. View in: PubMed

Assessment of NMYC amplification: a comparison of FISH, quantitative PCR monoplexing and traditional blotting methods used with formalin-fixed, paraffin-embedded neuroblastomas. Anal Quant Cytol Histol. 2005 Feb; 27(1):5-14. View in: PubMed

Enlarged and prominent nucleoli may be indicative of MYCN amplification: a study of neuroblastoma (Schwannian stroma-poor), undifferentiated/poorly differentiated subtype with high mitosis-karyorrhexis index. Cancer. 2005 Jan 1; 103(1):174-80. View in: PubMed

Neuroblastoma in an adult. Urology. 2004 Dec; 64(6):1232. View in: PubMed

A novel presenilin-1 mutation (Leu85Pro) in early-onset Alzheimer disease with spastic paraparesis. Arch Neurol. 2004 Nov; 61(11):1773-6. View in: PubMed

TrkA expression in peripheral neuroblastic tumors: prognostic significance and biological relevance. Cancer. 2004 Oct 15; 101(8):1873-81. View in: PubMed

First case of aplastic anemia in a Japanese child with a homozygous missense mutation in the NBS1 gene (I171V) associated with genomic instability. Hum Genet. 2004 Oct; 115(5):372-6. View in: PubMed

[Effects of introducing a risk manager for prevention of falls in a long-term care facility]. Nihon Ronen Igakkai Zasshi. 2004 Jul; 41(4):414-9. View in: PubMed

New intervention program for preventing falls among frail elderly people: the effects of perturbed walking exercise using a bilateral separated treadmill. Am J Phys Med Rehabil. 2004 Jul; 83(7):493-9. View in: PubMed

Colocolic intussusception associated with pneumatosis cystoides intestinalis after cord blood stem cell transplantation. J Pediatr Gastroenterol Nutr. 2004 May; 38(5):549-51. View in: PubMed

Correlation between indocyanine green angiographic findings and histopathology of polypoidal choroidal vasculopathy. Jpn J Ophthalmol. 2004 May-Jun; 48(3):249-55. View in: PubMed

[A randomized controlled trial of a treadmill training with the perturbation to improve the balance performance in the community dwelling elderly subjects]. Nihon Ronen Igakkai Zasshi. 2004 May; 41(3):321-7. View in: PubMed

The matrix metalloproteinase inhibitor prinomastat enhances photodynamic therapy responsiveness in a mouse tumor model. Cancer Res. 2004 Apr 1; 64(7):2328-32. View in: PubMed

The incidence of hyperglycemia in patients treated with olanzapine. J Clin Psychiatry. 2004 Mar; 65(3):443-4. View in: PubMed

Position-specific expression of Hox genes along the gastrointestinal tract. Congenit Anom (Kyoto). 2004 Mar; 44(1):18-26. View in: PubMed

Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment. Cancer Res. 2004 Mar 1; 64(5):1675-86. View in: PubMed

Pars plana suture fixation for intraocular lenses dislocated into the vitreous cavity using a closed-eye cow-hitch technique. J Cataract Refract Surg. 2004 Feb; 30(2):302-6. View in: PubMed

Epstein-Barr virus-associated posttransplant lymphoproliferative disorder after a cord blood stem cell transplantation presenting with pulmonary nodules. J Pediatr Hematol Oncol. 2004 Feb; 26(2):124-7. View in: PubMed

Large cell neuroblastoma: a distinct phenotype of neuroblastoma with aggressive clinical behavior. Cancer. 2004 Jan 15; 100(2):390-7. View in: PubMed

[Activity of the central nervous system and calcium]. Clin Calcium. 2004 Jan; 14(1):106-9. View in: PubMed

TraJ-dependent Escherichia coli K1 interactions with professional phagocytes are important for early systemic dissemination of infection in the neonatal rat. Infect Immun. 2004 Jan; 72(1):478-88. View in: PubMed

Revision of the International Neuroblastoma Pathology Classification: confirmation of favorable and unfavorable prognostic subsets in ganglioneuroblastoma, nodular. Cancer. 2003 Nov 15; 98(10):2274-81. View in: PubMed

[Surgical removal of juxtafoveal and extrafoveal choroidal neovascularization in age-related macular degeneration]. Nihon Ganka Gakkai Zasshi. 2003 Nov; 107(11):695-701. View in: PubMed

Citrobacter koseri brain abscess in the neonatal rat: survival and replication within human and rat macrophages. Infect Immun. 2003 Oct; 71(10):5871-80. View in: PubMed

Entry and intracellular replication of Escherichia coli K1 in macrophages require expression of outer membrane protein A. Infect Immun. 2003 Oct; 71(10):5951-61. View in: PubMed

Pediatric tumor cells express erythropoietin and a functional erythropoietin receptor that promotes angiogenesis and tumor cell survival. Lab Invest. 2003 Oct; 83(10):1477-87. View in: PubMed

[Surgical removal of choroidal neovascularization in angioid streaks]. Nihon Ganka Gakkai Zasshi. 2003 Aug; 107(8):440-4. View in: PubMed

Relationship with dynamic balance function during standing and walking. Am J Phys Med Rehabil. 2003 Jul; 82(7):511-6. View in: PubMed

Lytic bone lesions in human neuroblastoma xenograft involve osteoclast recruitment and are inhibited by bisphosphonate. Cancer Res. 2003 Jun 15; 63(12):3026-31. View in: PubMed

Anaplastic large cell lymphoma in Japanese children: retrospective analysis of 34 patients diagnosed at the National Research Institute for Child Health and Development. Br J Haematol. 2003 Apr; 121(1):94-6. View in: PubMed

Detecting functional asymmetries through the dipole moment of magnetoencephalography. J Neurol Sci. 2002 Jun 15; 198(1-2):51-61. View in: PubMed

Antidisialoganglioside/granulocyte macrophage-colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcgammaRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and azurophil granule exocytosis. Blood. 2002 Jun 1; 99(11):4166-73. View in: PubMed

Correspondence re: J. Mora et al. , Neuroblastic and Schwannian stromal cells of neuroblastoma are derived from a tumoral progenitor cell. Cancer Res. , 61: 6892-6898, 2001. Cancer Res. 2002 May 15; 62(10):2987-8; author reply 2988-9. View in: PubMed

Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors. Genes Chromosomes Cancer. 2002 May; 34(1):33-41. View in: PubMed

Vitrectomy for diabetic cystoid macular edema. Jpn J Ophthalmol. 2002 May-Jun; 46(3):315-22. View in: PubMed

alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. Int J Cancer. 2002 Apr 10; 98(5):690-7. View in: PubMed

[Relationship between lifestyle activities and physical functions in elderly persons utilizing care facilities]. Nihon Ronen Igakkai Zasshi. 2002 Mar; 39(2):197-203. View in: PubMed

Morphologic features of neuroblastoma (Schwannian stroma-poor tumors) in clinically favorable and unfavorable groups. Cancer. 2002 Mar 1; 94(5):1574-83. View in: PubMed

Shortening the duration of prone positioning after macular hole surgery- comparison between 1-week and 1-day prone positioning. Jpn J Ophthalmol. 2002 Jan-Feb; 46(1):84-8. View in: PubMed

[Preoperative factors influencing visual acuity following vitrectomy for exudative age-related macular degeneration]. Nihon Ganka Gakkai Zasshi. 2002 Jan; 106(1):16-22. View in: PubMed

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