Faculty

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Howard Neil Hodis, MD
Professor of Medicine
Harry J. Bauer and Dorothy Bauer Rawlins Professorship in Cardiology
Medicine
CSC 132 Health Sciences Campus Los Angeles
+1 323 442 1478

Overview

Dr. Hodis' clinical interests include lipid and atherosclerosis treatment and vascular screenings. His current research includes air pollution and atherosclerosis, characterization of the atherogenicity of cholesterol oxidation products, and development of non-invasive technologies for measuring atherosclerosis and vascular function, among others.

Dr. Hodis earned his medical degree Keck School of Medicine. He then went on to complete his internship and residency at LAC+USC Medical Center followed by an Edmondson Medical Research Fellowship.

Awards

North American Menopause Society: Thomas Clarkson Outstanding Clinical and Basic Science Research Award, 2010

USC: Alpha Mu Gamma, 1976

Western Society for Clinical Investigation: Member, 2008

Department of Family Medicine, USC: Outstanding Teacher Award, 1991

Phi Beta Kappa

USC: Outstanding Young Men of America Award, Phi Kappa Phi, 1976

American Heart Association: Fellow, 1991

Association of American Physicians: Member, 2008

Publications

Kurita K, Henderson VW, Gatz M, St John J, Hodis HN, Karim R, Mack WJ. Association of bilateral oophorectomy with cognitive function in healthy, postmenopausal women. Fertil Steril. 2016 Sep 1; 106(3):749-756. e2. View in: PubMed

Henderson VW, St John JA, Hodis HN, McCleary CA, Stanczyk FZ, Shoupe D, Kono N, Dustin L, Allayee H, Mack WJ. Cognitive effects of estradiol after menopause: A randomized trial of the timing hypothesis. Neurology. 2016 Aug 16; 87(7):699-708. View in: PubMed

Hanna DB, Guo M, Bužková P, Miller TL, Post WS, Stein JH, Currier JS, Kronmal RA, Freiberg MS, Bennett SN, Shikuma CM, Anastos K, Li Y, Tracy RP, Hodis HN, Delaney JA, Kaplan RC. HIV Infection and Carotid Artery Intima-media Thickness: Pooled Analyses Across 5 Cohorts of the NHLBI HIV-CVD Collaborative. Clin Infect Dis. 2016 Jul 15; 63(2):249-56. View in: PubMed

Ahmadi N, Ruiz-Garcia J, Hajsadeghi F, Azen S, Mack W, Hodis H, Lerman A. Impaired coronary artery distensibility is an endothelium-dependent process and is associated with vulnerable plaque composition. Clin Physiol Funct Imaging. 2016 Jul; 36(4):261-8. View in: PubMed

Chow DC, Kagihara JM, Zhang G, Souza SA, Hodis HN, Li Y, Mitchell BI, Nakamoto BK, Kallianpur KJ, Keating SM, Norris PJ, Kohorn LB, Ndhlovu LC, Shikuma CM. Non-classical monocytes predict progression of carotid artery bifurcation intima-media thickness in HIV-infected individuals on stable antiretroviral therapy. HIV Clin Trials. 2016 May; 17(3):114-22. View in: PubMed

Rettberg JR, Dang H, Hodis HN, Henderson VW, St John JA, Mack WJ, Brinton RD. Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer's risk metabolic phenotype. Neurobiol Aging. 2016 Apr; 40:155-63. View in: PubMed

Hodis HN, Mack WJ, Henderson VW, Shoupe D, Budoff MJ, Hwang-Levine J, Li Y, Feng M, Dustin L, Kono N, Stanczyk FZ, Selzer RH, Azen SP. Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol. N Engl J Med. 2016 Mar 31; 374(13):1221-31. View in: PubMed

Miller VM, Lahr BD, Bailey KR, Hodis HN, Mulvagh SL, Jayachandran M. Specific cell-derived microvesicles: Linking endothelial function to carotid artery intima-media thickness in low cardiovascular risk menopausal women. Atherosclerosis. 2016 Mar; 246:21-8. View in: PubMed

Miller VM, Jenkins GD, Biernacka JM, Heit JA, Huggins GS, Hodis HN, Budoff MJ, Lobo RA, Taylor HS, Manson JE, Black DM, Naftolin F, Harman SM, de Andrade M. Pharmacogenomics of estrogens on changes in carotid artery intima-medial thickness and coronary arterial calcification: Kronos Early Estrogen Prevention Study. Physiol Genomics. 2016 Jan; 48(1):33-41. View in: PubMed

Breton CV, Mack WJ, Yao J, Berhane K, Amadeus M, Lurmann F, Gilliland F, McConnell R, Hodis HN, Künzli N, Avol E. Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults. PLoS One. 2016; 11(3):e0150825. View in: PubMed

Lake JE, Seang S, Kelesidis T, Liao DH, Hodis HN, Stein JH, Currier JS. Telmisartan to reduce cardiovascular risk in older HIV-infected adults: a pilot study. HIV Clin Trials. 2015 Nov; 16(5):197-206. View in: PubMed

Stein JH, Ribaudo HJ, Hodis HN, Brown TT, Tran TT, Yan M, Brodell EL, Kelesidis T, McComsey GA, Dube MP, Murphy RL, Currier JS. A prospective, randomized clinical trial of antiretroviral therapies on carotid wall thickness. AIDS. 2015 Sep 10; 29(14):1775-83. View in: PubMed

Dubé MP, Komarow L, Fichtenbaum CJ, Cadden JJ, Overton ET, Hodis HN, Currier JS, Stein JH. Extended-Release Niacin Versus Fenofibrate in HIV-Infected Participants With Low High-Density Lipoprotein Cholesterol: Effects on Endothelial Function, Lipoproteins, and Inflammation. Clin Infect Dis. 2015 Sep 1; 61(5):840-9. View in: PubMed

Hanna DB, Post WS, Deal JA, Hodis HN, Jacobson LP, Mack WJ, Anastos K, Gange SJ, Landay AL, Lazar JM, Palella FJ, Tien PC, Witt MD, Xue X, Young MA, Kaplan RC, Kingsley LA. HIV Infection Is Associated With Progression of Subclinical Carotid Atherosclerosis. Clin Infect Dis. 2015 Aug 15; 61(4):640-50. View in: PubMed

Basaria S, Harman SM, Travison TG, Hodis H, Tsitouras P, Budoff M, Pencina KM, Vita J, Dzekov C, Mazer NA, Coviello AD, Knapp PE, Hally K, Pinjic E, Yan M, Storer TW, Bhasin S. Effects of Testosterone Administration for 3 Years on Subclinical Atherosclerosis Progression in Older Men With Low or Low-Normal Testosterone Levels: A Randomized Clinical Trial. JAMA. 2015 Aug 11; 314(6):570-81. View in: PubMed

Gleason CE, Dowling NM, Wharton W, Manson JE, Miller VM, Atwood CS, Brinton EA, Cedars MI, Lobo RA, Merriam GR, Neal-Perry G, Santoro NF, Taylor HS, Black DM, Budoff MJ, Hodis HN, Naftolin F, Harman SM, Asthana S. Effects of Hormone Therapy on Cognition and Mood in Recently Postmenopausal Women: Findings from the Randomized, Controlled KEEPS-Cognitive and Affective Study. PLoS Med. 2015 Jun; 12(6):e1001833. View in: PubMed

Hodis HN, Mack WJ. Hormone therapy and risk of all-cause mortality in women treated with statins. Menopause. 2015 Apr; 22(4):363-4. View in: PubMed

Hodis HN, Mack WJ, Shoupe D, Azen SP, Stanczyk FZ, Hwang-Levine J, Budoff MJ, Henderson VW. Methods and baseline cardiovascular data from the Early versus Late Intervention Trial with Estradiol testing the menopausal hormone timing hypothesis. Menopause. 2015 Apr; 22(4):391-401. View in: PubMed

Alexy T, Pais E, Wenby RB, Mack WJ, Hodis HN, Kono N, Wang J, Baskurt OK, Fisher TC, Meiselman HJ. Abnormal blood rheology and chronic low grade inflammation: Possible risk factors for accelerated atherosclerosis and coronary artery disease in Lewis negative subjects. Atherosclerosis. 2015 Mar; 239(1):248-51. View in: PubMed

Karim R, Stanczyk FZ, Brinton RD, Rettberg J, Hodis HN, Mack WJ. Association of endogenous sex hormones with adipokines and ghrelin in postmenopausal women. J Clin Endocrinol Metab. 2015 Feb; 100(2):508-15. View in: PubMed

Jung M, Parrinello CM, Xue X, Mack WJ, Anastos K, Lazar JM, Selzer RH, Shircore AM, Plankey M, Tien P, Cohen M, Gange SJ, Hodis HN, Kaplan RC. Echolucency of the Carotid Artery Intima-Media Complex and Intima-Media Thickness Have Different Cardiovascular Risk Factor Relationships: The Women's Interagency HIV Study. J Am Heart Assoc. 2015; 4(2). View in: PubMed

Karim R, Mack WJ, Kono N, Tien PC, Anastos K, Lazar J, Young M, Desai S, Golub ET, Kaplan RC, Hodis HN, Kovacs A. T-Cell Activation, Both Pre- and Post-HAART Levels, Correlates With Carotid Artery Stiffness Over 6. 5 Years Among HIV-Infected Women in the WIHS. J Acquir Immune Defic Syndr. 2014 Nov 1; 67(3):349-56. View in: PubMed

Lobo RA, Davis SR, De Villiers TJ, Gompel A, Henderson VW, Hodis HN, Lumsden MA, Mack WJ, Shapiro S, Baber RJ. Prevention of diseases after menopause. Climacteric. 2014 Oct; 17(5):540-56. View in: PubMed

Harman SM, Black DM, Naftolin F, Brinton EA, Budoff MJ, Cedars MI, Hopkins PN, Lobo RA, Manson JE, Merriam GR, Miller VM, Neal-Perry G, Santoro N, Taylor HS, Vittinghoff E, Yan M, Hodis HN. Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: a randomized trial. Ann Intern Med. 2014 Aug 19; 161(4):249-60. View in: PubMed

Hodis HN, Mack WJ. Hormone replacement therapy and the association with coronary heart disease and overall mortality: Clinical application of the timing hypothesis. J Steroid Biochem Mol Biol. 2014 Jul; 142:68-75. View in: PubMed

Breton CV, Park C, Siegmund K, Gauderman WJ, Whitfield-Maxwell L, Hodis HN, Avol E, Gilliland FD. NOS1 Methylation and Carotid Artery Intima-Media Thickness in Children. Circ Cardiovasc Genet. 2014 Apr 1; 7(2):116-22. View in: PubMed

John JA, Henderson VW, Hodis HN, Kono N, McCleary CA, Franke AA, Mack WJ. Associations Between Urine Excretion of Isoflavonoids and Cognition in Postmenopausal Women in the Women's Isoflavone Soy Health Clinical Trial. J Am Geriatr Soc. 2014 Apr; 62(4):629-35. View in: PubMed

Mucowski SJ, Mack WJ, Shoupe D, Kono N, Paulson R, Hodis HN. Effect of prior oophorectomy on changes in bone mineral density and carotid artery intima-media thickness in postmenopausal women. Fertil Steril. 2014 Apr; 101(4):1117-22. View in: PubMed

Baker JV, Hullsiek KH, Singh A, Wilson E, Henry K, Lichtenstein K, Onen N, Kojic E, Patel P, Brooks JT, Hodis HN, Budoff M, Sereti I. Immunologic predictors of coronary artery calcium progression in a contemporary HIV cohort. AIDS. 2014 Mar 27; 28(6):831-40. View in: PubMed

Hodis HN, Neves-e-Castro M. Menopausal hormone therapy and prevention of chronic diseases: IMS members react to the recent JAMA paper. Climacteric. 2014 Feb; 17(1):99-101. View in: PubMed

Wharton W, Gleason CE, Dowling NM, Carlsson CM, Brinton EA, Santoro MN, Neal-Perry G, Taylor H, Naftolin F, Lobo RA, Merriam G, Manson JE, Cedars MI, Miller VM, Black DM, Budoff M, Hodis HN, Harman SM, Asthana S. The KEEPS-Cognitive and Affective Study: Baseline Associations between Vascular Risk Factors and Cognition. J Alzheimers Dis. 2014 Jan 1; 40(2):331-41. View in: PubMed

Barbour JD, Jalbert EC, Chow DC, Gangcuangco LM, Norris PJ, Keating SM, Heitman J, Nagamine L, Seto T, Ndhlovu LC, Nakamoto BK, Hodis HN, Parikh NI, Shikuma CM. Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy. Atherosclerosis. 2014 Jan; 232(1):52-8. View in: PubMed

Hodis HN, Mack WJ. Response letter to Dr. Timo Strandberg. J Am Geriatr Soc. 2014 Jan; 62(1):206-7. View in: PubMed

Gatto NM, Henderson VW, Hodis HN, St John JA, Lurmann F, Chen JC, Mack WJ. Components of air pollution and cognitive function in middle-aged and older adults in Los Angeles. Neurotoxicology. 2014 Jan; 40:1-7. View in: PubMed

Szlachcic Y, Adkins RH, Reiter JC, Yee F, Shaw SJ, Hodis HN. Predictors of subclinical atherosclerosis in women with spinal cord injury. Top Spinal Cord Inj Rehabil. 2014; 20(2):90-5. View in: PubMed

Henderson VW, St John JA, Hodis HN, McCleary CA, Stanczyk FZ, Karim R, Shoupe D, Kono N, Dustin L, Allayee H, Mack WJ. Cognition, mood, and physiological concentrations of sex hormones in the early and late postmenopause. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20290-5. View in: PubMed

Toledo-Corral CM, Myers SJ, Li Y, Hodis HN, Goran MI, Weigensberg MJ. Blunted nocturnal cortisol rise is associated with higher carotid artery intima-media thickness (CIMT) in overweight African American and Latino youth. Psychoneuroendocrinology. 2013 Sep; 38(9):1658-67. View in: PubMed

Quaas AM, Kono N, Mack WJ, Hodis HN, Felix JC, Paulson RJ, Shoupe D. Effect of isoflavone soy protein supplementation on endometrial thickness, hyperplasia, and endometrial cancer risk in postmenopausal women: a randomized controlled trial. Menopause. 2013 Aug; 20(8):840-4. View in: PubMed

Ogorodnikova AD, Khan UI, McGinn AP, Zeb I, Budoff MJ, Harman SM, Miller VM, Brinton EA, Manson JE, Hodis HN, Merriam GR, Cedars MI, Taylor HS, Naftolin F, Lobo RA, Santoro N, Wildman RP. Ectopic fat and adipokines in metabolically benign overweight/obese women: the Kronos Early Estrogen Prevention Study. Obesity (Silver Spring). 2013 Aug; 21(8):1726-33. View in: PubMed

Breton CV, Wang X, Mack WJ, Berhane K, Lopez M, Islam TS, Feng M, Lurmann F, McConnell R, Hodis HN, Künzli N, Avol E. Response to letter regarding article, “Childhood air pollutant exposure and carotid artery intima–media thickness in young adults”. Circulation. 2013 Jun 4; 127(22):e659. View in: PubMed

Hodis HN, Mack WJ. The timing hypothesis and hormone replacement therapy: a paradigm shift in the primary prevention of coronary heart disease in women. Part 2: comparative risks. J Am Geriatr Soc. 2013 Jun; 61(6):1011-8. View in: PubMed

Hodis HN, Mack WJ. The timing hypothesis and hormone replacement therapy: a paradigm shift in the primary prevention of coronary heart disease in women. Part 1: comparison of therapeutic efficacy. J Am Geriatr Soc. 2013 Jun; 61(6):1005-10. View in: PubMed

Kelesidis T, Kendall MA, Yang OO, Hodis H, Currier JS. Perturbations of circulating levels of RANKL-osteoprotegerin axis in relation to lipids and progression of atherosclerosis in HIV-infected and -uninfected adults: ACTG NWCS 332/A5078 Study. AIDS Res Hum Retroviruses. 2013 Jun; 29(6):938-48. View in: PubMed

Parrinello CM, Landay AL, Hodis HN, Gange SJ, Norris PJ, Young M, Anastos K, Tien PC, Xue X, Lazar J, Benning L, Tracy RP, Kaplan RC. Treatment-related changes in serum lipids and inflammation: clinical relevance remains unclear. Analyses from the Women's Interagency HIV study. AIDS. 2013 Jun 1; 27(9):1516-9. View in: PubMed

Dratva J, Breton CV, Hodis HN, Mack WJ, Salam MT, Zemp E, Gilliland F, Kuenzli N, Avol E. Birth weight and carotid artery intima-media thickness. J Pediatr. 2013 May; 162(5):906-11. e1-2. View in: PubMed

Karim R, Mack WJ, Kono N, Tien PC, Anastos K, Lazar J, Young M, Cohen M, Golub E, Greenblatt RM, Kaplan RC, Hodis HN. Gonadotropin and sex steroid levels in HIV-infected premenopausal women and their association with subclinical atherosclerosis in HIV-infected and -uninfected women in the women's interagency HIV study (WIHS). J Clin Endocrinol Metab. 2013 Apr; 98(4):E610-8. View in: PubMed

Wolff EF, He Y, Black DM, Brinton EA, Budoff MJ, Cedars MI, Hodis HN, Lobo RA, Manson JE, Merriam GR, Miller VM, Naftolin F, Pal L, Santoro N, Zhang H, Harman SM, Taylor HS. Self-reported menopausal symptoms, coronary artery calcification, and carotid intima-media thickness in recently menopausal women screened for the Kronos early estrogen prevention study (KEEPS). Fertil Steril. 2013 Apr; 99(5):1385-91. View in: PubMed

Stein JH, Brown TT, Ribaudo HJ, Chen Y, Yan M, Lauer-Brodell E, McComsey GA, Dubé MP, Murphy RL, Hodis HN, Currier JS. Ultrasonographic measures of cardiovascular disease risk in antiretroviral treatment-naive individuals with HIV infection. AIDS. 2013 Mar 27; 27(6):929-37. View in: PubMed

Saremi A, Schwenke DC, Buchanan TA, Hodis HN, Mack WJ, Banerji M, Bray GA, Clement SC, Henry RR, Kitabchi AE, Mudaliar S, Ratner RE, Stentz FB, Musi N, Tripathy D, DeFronzo RA, Reaven PD. Pioglitazone slows progression of atherosclerosis in prediabetes independent of changes in cardiovascular risk factors. Arterioscler Thromb Vasc Biol. 2013 Feb; 33(2):393-9. View in: PubMed

Miller VM, Petterson TM, Jeavons EN, Lnu AS, Rider DN, Heit JA, Cunningham JM, Huggins GS, Hodis HN, Budoff MJ, Santoro N, Hopkins PN, Lobo RA, Manson JE, Naftolin F, Taylor HS, Harman SM, de Andrade M. Genetic polymorphisms associated with carotid artery intima-media thickness and coronary artery calcification in women of the Kronos Early Estrogen Prevention Study. Physiol Genomics. 2013 Jan 15; 45(2):79-88. View in: PubMed

Kelesidis T, Yang OO, Kendall MA, Hodis HN, Currier JS. Dysfunctional HDL and progression of atherosclerosis in HIV-1-infected and -uninfected adults. Lipids Health Dis. 2013; 12:23. View in: PubMed

Dowling NM, Gleason CE, Manson JE, Hodis HN, Miller VM, Brinton EA, Neal-Perry G, Santoro MN, Cedars M, Lobo R, Merriam GR, Wharton W, Naftolin F, Taylor H, Harman SM, Asthana S. Characterization of vascular disease risk in postmenopausal women and its association with cognitive performance. PLoS One. 2013; 8(7):e68741. View in: PubMed

Parrinello CM, Landay AL, Hodis HN, Gange SJ, Norris PJ, Young M, Anastos K, Tien PC, Xue X, Lazar J, Benning L, Tracy RP, Kaplan RC. Association of subclinical atherosclerosis with lipid levels amongst antiretroviral-treated and untreated HIV-infected women in the Women's Interagency HIV study. Atherosclerosis. 2012 Dec; 225(2):408-11. View in: PubMed

Kelesidis T, Kendall MA, Yang OO, Hodis HN, Currier JS. Biomarkers of Microbial Translocation and Macrophage Activation: Association With Progression of Subclinical Atherosclerosis in HIV-1 Infection. J Infect Dis. 2012 Nov; 206(10):1558-67. View in: PubMed

Cardenas VA, Reed B, Chao LL, Chui H, Sanossian N, Decarli CC, Mack W, Kramer J, Hodis HN, Yan M, Buonocore MH, Carmichael O, Jagust WJ, Weiner MW. Associations among vascular risk factors, carotid atherosclerosis, and cortical volume and thickness in older adults. Stroke. 2012 Nov; 43(11):2865-70. View in: PubMed

Breton CV, Wang X, Mack WJ, Berhane K, Lopez M, Islam TS, Feng M, Lurmann F, McConnell R, Hodis HN, Künzli N, Avol E. Childhood air pollutant exposure and carotid artery intima-media thickness in young adults. Circulation. 2012 Sep 25; 126(13):1614-20. View in: PubMed

Kaplan RC, Landay AL, Hodis HN, Gange SJ, Norris PJ, Young M, Anastos K, Tien PC, Xue X, Lazar J, Parrinello CM, Benning L, Tracy RP. Potential cardiovascular disease risk markers among HIV-infected women initiating antiretroviral treatment. J Acquir Immune Defic Syndr. 2012 Aug 1; 60(4):359-68. View in: PubMed

Hechter RC, Budoff M, Hodis HN, Rinaldo CR, Jenkins FJ, Jacobson LP, Kingsley LA, Taiwo B, Post WS, Margolick JB, Detels R. Herpes simplex virus type 2 (HSV-2) as a coronary atherosclerosis risk factor in HIV-infected men: Multicenter AIDS Cohort Study. Atherosclerosis. 2012 Aug; 223(2):433-6. View in: PubMed

Shikuma CM, Seto T, Liang CY, Bennett K, Degruttola V, Gerschenson M, Stein JH, Budoff M, Hodis HN, Delaney JA, Ogata-Arakaki D, Pramyothin P, Chow D. Vitamin D Levels and Markers of Arterial Dysfunction in HIV. AIDS Res Hum Retroviruses. 2012 Aug; 28(8):793-7. View in: PubMed

Henderson VW, St John JA, Hodis HN, Kono N, McCleary CA, Franke AA, Mack WJ. Long-term soy isoflavone supplementation and cognition in women: A randomized, controlled trial. Neurology. 2012 Jun 5; 78(23):1841-8. View in: PubMed

Franke AA, Lai JF, Halm BM, Pagano I, Kono N, Mack WJ, Hodis HN. Equol production changes over time in postmenopausal women. J Nutr Biochem. 2012 Jun; 23(6):573-9. View in: PubMed

Hodis HN, Collins P, Mack WJ, Schierbeck LL. The timing hypothesis for coronary heart disease prevention with hormone therapy: past, present and future in perspective. Climacteric. 2012 Jun; 15(3):217-28. View in: PubMed

Parrinello CM, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Hunt PW, Deeks SG, Hodis HN, Kaplan RC. Cytomegalovirus Immunoglobulin G Antibody Is Associated With Subclinical Carotid Artery Disease Among HIV-Infected Women. J Infect Dis. 2012 Jun; 205(12):1788-96. View in: PubMed

Huang G, Wang D, Zeb I, Budoff MJ, Harman SM, Miller V, Brinton EA, El Khoudary SR, Manson JE, Sowers MR, Hodis HN, Merriam GR, Cedars MI, Taylor HS, Naftolin F, Lobo RA, Santoro N, Wildman RP. Intra-thoracic fat, cardiometabolic risk factors, and subclinical cardiovascular disease in healthy, recently menopausal women screened for the Kronos Early Estrogen Prevention Study (KEEPS). Atherosclerosis. 2012 Mar; 221(1):198-205. View in: PubMed

Huang G, Wang D, Khan UI, Zeb I, Manson JE, Miller V, Hodis HN, Budoff MJ, Merriam GR, Harman MS, Brinton EA, Cedars MI, Su Y, Lobo RA, Naftolin F, Santoro N, Taylor HS, Wildman RP. Associations between retinol-binding protein 4 and cardiometabolic risk factors and subclinical atherosclerosis in recently postmenopausal women: cross-sectional analyses from the KEEPS study. Cardiovasc Diabetol. 2012; 11:52. View in: PubMed

Stevenson JC, Hodis HN, Pickar JH, Lobo RA. HRT and breast cancer risk: a realistic perspective. Climacteric. 2011 Dec; 14(6):633-6. View in: PubMed

Jayachandran M, Litwiller RD, Lahr BD, Bailey KR, Owen WG, Mulvagh SL, Heit JA, Hodis HN, Harman SM, Miller VM. Alterations in platelet function and cell-derived microvesicles in recently menopausal women: relationship to metabolic syndrome and atherogenic risk. J Cardiovasc Transl Res. 2011 Dec; 4(6):811-22. View in: PubMed

Karim R, Dell RM, Greene DF, Mack WJ, Gallagher JC, Hodis HN. Hip fracture in postmenopausal women after cessation of hormone therapy: results from a prospective study in a large health management organization. Menopause. 2011 Nov; 18(11):1172-7. View in: PubMed

Hodis HN, Mack WJ, Kono N, Azen SP, Shoupe D, Hwang-Levine J, Petitti D, Whitfield-Maxwell L, Yan M, Franke AA, Selzer RH. Isoflavone soy protein supplementation and atherosclerosis progression in healthy postmenopausal women: a randomized controlled trial. Stroke. 2011 Nov; 42(11):3168-75. View in: PubMed

Baker JV, Henry WK, Patel P, Bush TJ, Conley LJ, Mack WJ, Overton ET, Budoff M, Hammer J, Carpenter CC, Hodis HN, Brooks JT. Progression of carotid intima-media thickness in a contemporary human immunodeficiency virus cohort. Clin Infect Dis. 2011 Oct; 53(8):826-35. View in: PubMed

Choudhury F, Bernstein L, Hodis HN, Stanczyk FZ, Mack WJ. Physical activity and sex hormone levels in estradiol- and placebo-treated postmenopausal women. Menopause. 2011 Oct; 18(10):1079-86. View in: PubMed

Hwang-Levine J, Stanczyk FZ, Hodis HN. The role of progestogens in regulating matrix metalloproteinase activity in macrophages and microglial cells. Neurochem Res. 2011 Oct; 36(10):1870-5. View in: PubMed

Breton CV, Wang X, Mack WJ, Berhane K, Lopez M, Islam TS, Feng M, Hodis HN, Künzli N, Avol E. Carotid artery intima-media thickness in college students: race/ethnicity matters. Atherosclerosis. 2011 Aug; 217(2):441-6. View in: PubMed

Kaplan RC, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Parrinello CM, Hunt P, Deeks SG, Hodis HN. T cell activation predicts carotid artery stiffness among HIV-infected women. Atherosclerosis. 2011 Jul; 217(1):207-13. View in: PubMed

Toledo-Corral CM, Davis JN, Alderete TL, Weigensberg MJ, Ayala CT, Li Y, Hodis HN, Goran MI. Subclinical atherosclerosis in Latino youth: progression of carotid intima-media thickness and its relationship to cardiometabolic risk factors. J Pediatr. 2011 Jun; 158(6):935-40. View in: PubMed

DeFronzo RA, Tripathy D, Schwenke DC, Banerji M, Bray GA, Buchanan TA, Clement SC, Henry RR, Hodis HN, Kitabchi AE, Mack WJ, Mudaliar S, Ratner RE, Williams K, Stentz FB, Musi N, Reaven PD. Pioglitazone for diabetes prevention in impaired glucose tolerance. N Engl J Med. 2011 Mar 24; 364(12):1104-15. View in: PubMed

Hodis HN, Mack WJ. A "window of opportunity:" The reduction of coronary heart disease and total mortality with menopausal therapies is age- and time-dependent. Brain Res. 2011 Mar 16; 1379:244-52. View in: PubMed

Kaplan RC, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Hunt P, Karim R, Kern DM, Hodis HN, Deeks SG. T cell activation and senescence predict subclinical carotid artery disease in HIV-infected women. J Infect Dis. 2011 Feb 15; 203(4):452-63. View in: PubMed

Peck A, Chaikittisilpa S, Mirzaei R, Wang J, Mack WJ, Hodis HN, Stanczyk FZ. Effect of statins on estrogen and androgen levels in postmenopausal women treated with estradiol. Climacteric. 2011 Feb; 14(1):49-53. View in: PubMed

Seaberg EC, Benning L, Sharrett AR, Lazar JM, Hodis HN, Mack WJ, Siedner MJ, Phair JP, Kingsley LA, Kaplan RC. Association between human immunodeficiency virus infection and stiffness of the common carotid artery. Stroke. 2010 Oct; 41(10):2163-70. View in: PubMed

Franke AA, Hebshi SM, Pagano I, Kono N, Mack WJ, Hodis HN. Urine accurately reflects circulating isoflavonoids and ascertains compliance during soy intervention. Cancer Epidemiol Biomarkers Prev. 2010 Jul; 19(7):1775-83. View in: PubMed

Karim R, Stanczyk FZ, Hodis HN, Cushman M, Lobo RA, Hwang J, Mack WJ. Associations between markers of inflammation and physiological and pharmacological levels of circulating sex hormones in postmenopausal women. Menopause. 2010 Jul; 17(4):785-90. View in: PubMed

Stevenson JC, Hodis HN, Pickar JH, Lobo RA. Drug firm conflicting interests. If only WHI was done well. BMJ. 2010; 340:c591. View in: PubMed

Künzli N, Jerrett M, Garcia-Esteban R, Basagaña X, Beckermann B, Gilliland F, Medina M, Peters J, Hodis HN, Mack WJ. Ambient air pollution and the progression of atherosclerosis in adults. PLoS One. 2010; 5(2):e9096. View in: PubMed

Stevenson JC, Hodis HN, Pickar JH, Lobo RA. Coronary heart disease and menopause management: the swinging pendulum of HRT. Atherosclerosis. 2009 Dec; 207(2):336-40. View in: PubMed

Karim R, Mack WJ, Hodis HN, Roy S, Stanczyk FZ. Influence of age and obesity on serum estradiol, estrone, and sex hormone binding globulin concentrations following oral estrogen administration in postmenopausal women. J Clin Endocrinol Metab. 2009 Nov; 94(11):4136-43. View in: PubMed

Toledo-Corral CM, Ventura EE, Hodis HN, Weigensberg MJ, Lane CJ, Li Y, Goran MI. Persistence of the metabolic syndrome and its influence on carotid artery intima media thickness in overweight Latino children. Atherosclerosis. 2009 Oct; 206(2):594-8. View in: PubMed

Miller VM, Black DM, Brinton EA, Budoff MJ, Cedars MI, Hodis HN, Lobo RA, Manson JE, Merriam GR, Naftolin F, Santoro N, Taylor HS, Harman SM. Using basic science to design a clinical trial: baseline characteristics of women enrolled in the Kronos Early Estrogen Prevention Study (KEEPS). J Cardiovasc Transl Res. 2009 Sep; 2(3):228-39. View in: PubMed

Tien PC, Schneider MF, Cole SR, Cohen MH, Glesby MJ, Lazar J, Young M, Mack W, Hodis HN, Kaplan RC. Association of hepatitis C virus and HIV infection with subclinical atherosclerosis in the women's interagency HIV study. AIDS. 2009 Aug 24; 23(13):1781-4. View in: PubMed

Goodarzi MO, Taylor KD, Jones MR, Fang B, Guo X, Xiang AH, Buchanan TA, Hodis HN, Raffel LJ, Rotter JI. Replication of calpain-10 genetic association with carotid intima-media thickness. Atherosclerosis. 2009 Aug; 205(2):503-5. View in: PubMed

Gatto NM, Henderson VW, St John JA, McCleary C, Detrano R, Hodis HN, Mack WJ. Subclinical atherosclerosis is weakly associated with lower cognitive function in healthy hyperhomocysteinemic adults without clinical cardiovascular disease. Int J Geriatr Psychiatry. 2009 Apr; 24(4):390-9. View in: PubMed

Hodis HN, Mack WJ, Dustin L, Mahrer PR, Azen SP, Detrano R, Selhub J, Alaupovic P, Liu CR, Liu CH, Hwang J, Wilcox AG, Selzer RH. High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomized controlled trial. Stroke. 2009 Mar; 40(3):730-6. View in: PubMed

St John JA, Henderson VW, Gatto NM, McCleary CA, Spencer CA, Hodis HN, Mack WJ. Mildly elevated TSH and cognition in middle-aged and older adults. Thyroid. 2009 Feb; 19(2):111-7. View in: PubMed

Allayee H, Roth N, Hodis HN. Polyunsaturated fatty acids and cardiovascular disease: implications for nutrigenetics. J Nutrigenet Nutrigenomics. 2009; 2(3):140-8. View in: PubMed

Hodis HN, Mack WJ. Coronary heart disease and hormone replacement therapy after the menopause. Climacteric. 2009; 12 Suppl 1:71-5. View in: PubMed

Karim R, Hodis HN, Detrano R, Liu CR, Liu CH, Mack WJ. Relation of Framingham risk score to subclinical atherosclerosis evaluated across three arterial sites. Am J Cardiol. 2008 Oct 1; 102(7):825-30. View in: PubMed

Gatto NM, Henderson VW, St John JA, McCleary C, Hodis HN, Mack WJ. Metabolic syndrome and cognitive function in healthy middle-aged and older adults without diabetes. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2008 Sep; 15(5):627-41. View in: PubMed

Hodis HN, Mack WJ. Postmenopausal hormone therapy and cardiovascular disease in perspective. Clin Obstet Gynecol. 2008 Sep; 51(3):564-80. View in: PubMed

Kaplan RC, Kingsley LA, Gange SJ, Benning L, Jacobson LP, Lazar J, Anastos K, Tien PC, Sharrett AR, Hodis HN. Low CD4+ T-cell count as a major atherosclerosis risk factor in HIV-infected women and men. AIDS. 2008 Aug 20; 22(13):1615-24. View in: PubMed

Brinton EA, Hodis HN, Merriam GR, Harman SM, Naftolin F. Can menopausal hormone therapy prevent coronary heart disease? Trends Endocrinol Metab. 2008 Aug; 19(6):206-12. View in: PubMed

Utian WH, Archer DF, Bachmann GA, Gallagher C, Grodstein F, Heiman JR, Henderson VW, Hodis HN, Karas RH, Lobo RA, Manson JE, Reid RL, Schmidt PJ, Stuenkel CA. Estrogen and progestogen use in postmenopausal women: July 2008 position statement of The North American Menopause Society. Menopause. 2008 Jul-Aug; 15(4 Pt 1):584-602. View in: PubMed

Xiang AH, Hodis HN, Kawakubo M, Peters RK, Kjos SL, Marroquin A, Goico J, Ochoa C, Liu CR, Liu CH, Buchanan TA. Effect of pioglitazone on progression of subclinical atherosclerosis in non-diabetic premenopausal Hispanic women with prior gestational diabetes. Atherosclerosis. 2008 Jul; 199(1):207-14. View in: PubMed

McKenzie M, Sikon AL, Thacker HL, Gass M, Hodis HN, Jenkins MR. Putting the latest data into practice: case studies and clinical considerations in menopausal management. Cleve Clin J Med. 2008 May; 75 Suppl 4:S25-33. View in: PubMed

Hodis HN. Assessing benefits and risks of hormone therapy in 2008: new evidence, especially with regard to the heart. Cleve Clin J Med. 2008 May; 75 Suppl 4:S3-12. View in: PubMed

Chen YC, Guo X, Raffel LJ, Xiang AH, Fang B, Hsueh WA, Taylor KD, Buchanan TA, Hodis HN, Rotter JI. Carotid intima-media thickness (cIMT) cosegregates with blood pressure and renal function in hypertensive Hispanic families. Atherosclerosis. 2008 May; 198(1):160-5. View in: PubMed

Hodis HN, St John JA, Xiang M, Cushman M, Lobo RA, Mack WJ. Inflammatory markers and progression of subclinical atherosclerosis in healthy postmenopausal women (from the Estrogen in the Prevention of Atherosclerosis Trial). Am J Cardiol. 2008 Apr 15; 101(8):1131-3. View in: PubMed

Gatto NM, Hodis HN, Liu CR, Liu CH, Mack WJ. Brachial artery vasoreactivity is associated with cross-sectional and longitudinal anatomical measures of atherosclerosis in postmenopausal women with coronary artery disease. Atherosclerosis. 2008 Feb; 196(2):674-81. View in: PubMed

Karim R, Hodis HN, Stanczyk FZ, Lobo RA, Mack WJ. Relationship between serum levels of sex hormones and progression of subclinical atherosclerosis in postmenopausal women. J Clin Endocrinol Metab. 2008 Jan; 93(1):131-8. View in: PubMed

Hodis HN, Mack WJ. Estrogen therapy and coronary-artery calcification. N Engl J Med. 2007 Sep 20; 357(12):1252-3; author reply 1254. View in: PubMed

Hodis HN, Mack WJ. Postmenopausal hormone therapy in clinical perspective. Menopause. 2007 Sep-Oct; 14(5):944-57. View in: PubMed

Vigen C, Hodis HN, Chandler WL, Lobo RA, Mack WJ. Postmenopausal oral estrogen therapy affects hemostatic factors, but does not account for reduction in the progression of subclinical atherosclerosis. J Thromb Haemost. 2007 Jun; 5(6):1201-8. View in: PubMed

Currier JS, Kendall MA, Henry WK, Alston-Smith B, Torriani FJ, Tebas P, Li Y, Hodis HN. Progression of carotid artery intima-media thickening in HIV-infected and uninfected adults. AIDS. 2007 May 31; 21(9):1137-45. View in: PubMed

Mack WJ, Dhungana B, Dowsett SA, Keech CA, Feng M, Li Y, Hodis HN. Carotid artery intima-media thickness after raloxifene treatment. J Womens Health (Larchmt). 2007 Apr; 16(3):370-8. View in: PubMed

Zheng L, Hodis HN, Buchanan TA, Li Y, Mack WJ. Effect of antihypertensive therapy on progression of carotid intima-media thickness in patients with type 2 diabetes mellitus. Am J Cardiol. 2007 Apr 1; 99(7):956-60. View in: PubMed

Steiner AZ, Xiang M, Mack WJ, Shoupe D, Felix JC, Lobo RA, Hodis HN. Unopposed estradiol therapy in postmenopausal women: results from two randomized trials. Obstet Gynecol. 2007 Mar; 109(3):581-7. View in: PubMed

Hwang J, Hodis HN, Hsiai TK, Asatryan L, Sevanian A. Role of annexin II in estrogen-induced macrophage matrix metalloproteinase-9 activity: the modulating effect of statins. Atherosclerosis. 2006 Nov; 189(1):76-82. View in: PubMed

Hwang J, Rouhanizadeh M, Hamilton RT, Lin TC, Eiserich JP, Hodis HN, Hsiai TK. 17beta-Estradiol reverses shear-stress-mediated low density lipoprotein modifications. Free Radic Biol Med. 2006 Aug 15; 41(4):568-78. View in: PubMed

Hodis HN, Mack WJ, Zheng L, Li Y, Torres M, Sevilla D, Stewart Y, Hollen B, Garcia K, Alaupovic P, Buchanan TA. Effect of peroxisome proliferator-activated receptor gamma agonist treatment on subclinical atherosclerosis in patients with insulin-requiring type 2 diabetes. Diabetes Care. 2006 Jul; 29(7):1545-53. View in: PubMed

Currier JS, Kendall MA, Henry WK, Torriani FJ, Hodis HN. Response to: 'carotid intima-media thickness: assessment of sub-clinical atherosclerosis in HIV-infected patients'. AIDS. 2006 Jan 9; 20(2):311. View in: PubMed

Steiner AZ, Hodis HN, Lobo RA, Shoupe D, Xiang M, Mack WJ. Postmenopausal oral estrogen therapy and blood pressure in normotensive and hypertensive subjects: the Estrogen in the Prevention of Atherosclerosis Trial. Menopause. 2005 Nov-Dec; 12(6):728-33. View in: PubMed

Hwang J, Mack WJ, Xiang M, Sevanian A, Lobo RA, Hodis HN. Long-term effect of estrogen replacement on plasma nitric oxide levels: results from the estrogen in the prevention of atherosclerosis trial (EPAT). Atherosclerosis. 2005 Aug; 181(2):375-80. View in: PubMed

Karim R, Mack WJ, Lobo RA, Hwang J, Liu CR, Liu CH, Sevanian A, Hodis HN. Determinants of the effect of estrogen on the progression of subclinical atherosclerosis: Estrogen in the Prevention of Atherosclerosis Trial. Menopause. 2005 Jul-Aug; 12(4):366-73. View in: PubMed

Currier JS, Kendall MA, Zackin R, Henry WK, Alston-Smith B, Torriani FJ, Schouten J, Mickelberg K, Li Y, Hodis HN. Carotid artery intima-media thickness and HIV infection: traditional risk factors overshadow impact of protease inhibitor exposure. AIDS. 2005 Jun 10; 19(9):927-33. View in: PubMed

Vigen C, Hodis HN, Selzer RH, Mahrer PR, Mack WJ. Relation of progression of coronary artery atherosclerosis to risk of cardiovascular events (from the Monitored Atherosclerosis Regression Study). Am J Cardiol. 2005 Jun 1; 95(11):1277-82. View in: PubMed

Xiang AH, Peters RK, Kjos SL, Ochoa C, Marroquin A, Goico J, Tan S, Wang C, Azen SP, Liu CR, Liu CH, Hodis HN, Buchanan TA. Effect of thiazolidinedione treatment on progression of subclinical atherosclerosis in premenopausal women at high risk for type 2 diabetes. J Clin Endocrinol Metab. 2005 Apr; 90(4):1986-91. View in: PubMed

Goodarzi MO, Taylor KD, Guo X, Quiñones MJ, Cui J, Li Y, Saad MF, Yang H, Hsueh WA, Hodis HN, Rotter JI. Association of the diabetes gene calpain-10 with subclinical atherosclerosis: the Mexican-American Coronary Artery Disease Study. Diabetes. 2005 Apr; 54(4):1228-32. View in: PubMed

Wang D, Yang H, Quiñones MJ, Bulnes-Enriquez I, Jimenez X, De La Rosa R, Modilevsky T, Yu K, Li Y, Taylor KD, Hsueh WA, Hodis HN, Rotter JI. A genome-wide scan for carotid artery intima-media thickness: the Mexican-American Coronary Artery Disease family study. Stroke. 2005 Mar; 36(3):540-5. View in: PubMed

Künzli N, Jerrett M, Mack WJ, Beckerman B, LaBree L, Gilliland F, Thomas D, Peters J, Hodis HN. Ambient air pollution and atherosclerosis in Los Angeles. Environ Health Perspect. 2005 Feb; 113(2):201-6. View in: PubMed

Karim R, Buchanan TA, Hodis HN, Li Y, Mack WJ. The association of smoking and subclinical atherosclerosis in Type 2 diabetes: modification by duration of diabetes. Diabet Med. 2005 Jan; 22(1):81-7. View in: PubMed

Lord SJ, Mack WJ, Van Den Berg D, Pike MC, Ingles SA, Haiman CA, Wang W, Parisky YR, Hodis HN, Ursin G. Polymorphisms in genes involved in estrogen and progesterone metabolism and mammographic density changes in women randomized to postmenopausal hormone therapy: results from a pilot study. Breast Cancer Res. 2005; 7(3):R336-44. View in: PubMed

Wong M, Papa A, Lang T, Hodis HN, Labree L, Detrano R. Validation of thoracic quantitative computed tomography as a method to measure bone mineral density. Calcif Tissue Int. 2005 Jan; 76(1):7-10. View in: PubMed

Krantz JS, Mack WJ, Hodis HN, Liu CR, Liu CH, Kaufman FR. Early onset of subclinical atherosclerosis in young persons with type 1 diabetes. J Pediatr. 2004 Oct; 145(4):452-7. View in: PubMed

Mack WJ, Slater CC, Xiang M, Shoupe D, Lobo RA, Hodis HN. Elevated subclinical atherosclerosis associated with oophorectomy is related to time since menopause rather than type of menopause. Fertil Steril. 2004 Aug; 82(2):391-7. View in: PubMed

Xiang AH, Peters RK, Kjos SL, Goico J, Ochoa C, Marroquin A, Tan S, Hodis HN, Azen SP, Buchanan TA. Pharmacological treatment of insulin resistance at two different stages in the evolution of type 2 diabetes: impact on glucose tolerance and beta-cell function. J Clin Endocrinol Metab. 2004 Jun; 89(6):2846-51. View in: PubMed

Zheng L, Buchanan TA, Hodis HN, Li Y, Torres M, Mack WJ. Time from diagnosis of type 2 diabetes to initiation of insulin therapy is related to carotid artery intima-media thickness. Atherosclerosis. 2003 Oct; 170(2):293-9. View in: PubMed

Hodis HN, Mack WJ, Azen SP, Lobo RA, Shoupe D, Mahrer PR, Faxon DP, Cashin-Hemphill L, Sanmarco ME, French WJ, Shook TL, Gaarder TD, Mehra AO, Rabbani R, Sevanian A, Shil AB, Torres M, Vogelbach KH, Selzer RH. Hormone therapy and the progression of coronary-artery atherosclerosis in postmenopausal women. N Engl J Med. 2003 Aug 7; 349(6):535-45. View in: PubMed

Mack WJ, Islam T, Lee Z, Selzer RH, Hodis HN. Environmental tobacco smoke and carotid arterial stiffness. Prev Med. 2003 Aug; 37(2):148-54. View in: PubMed

Hodis HN, Mack WJ, Lobo RA. Randomized controlled trial evidence that estrogen replacement therapy reduces the progression of subclinical atherosclerosis in healthy postmenopausal women without preexisting cardiovascular disease. Circulation. 2003 Jul 8; 108(1):e5; author reply e5. View in: PubMed

Hwang J, Wang J, Morazzoni P, Hodis HN, Sevanian A. The phytoestrogen equol increases nitric oxide availability by inhibiting superoxide production: an antioxidant mechanism for cell-mediated LDL modification. Free Radic Biol Med. 2003 May 15; 34(10):1271-82. View in: PubMed

Mack WJ, Hameed AB, Xiang M, Roy S, Slater CC, Stanczyk FZ, Lobo RA, Liu CR, Liu CH, Hodis HN. Does elevated body mass modify the influence of postmenopausal estrogen replacement on atherosclerosis progression: results from the estrogen in the prevention of atherosclerosis trial. Atherosclerosis. 2003 May; 168(1):91-8. View in: PubMed

Hodis HN, Mack WJ, Lobo R. What is the cardioprotective role of hormone replacement therapy? Curr Atheroscler Rep. 2003 Jan; 5(1):56-66. View in: PubMed

Calverley DC, Brass E, Hacker MR, Tsao-Wei DD, Espina BM, Pullarkat VA, Hodis HN, Groshen S. Potential role of platelet FcgammaRIIA in collagen-mediated platelet activation associated with atherothrombosis. Atherosclerosis. 2002 Oct; 164(2):261-7. View in: PubMed

Hodis HN, Mack WJ, LaBree L, Mahrer PR, Sevanian A, Liu CR, Liu CH, Hwang J, Selzer RH, Azen SP. Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis: the Vitamin E Atherosclerosis Prevention Study (VEAPS). Circulation. 2002 Sep 17; 106(12):1453-9. View in: PubMed

Buchanan TA, Xiang AH, Peters RK, Kjos SL, Marroquin A, Goico J, Ochoa C, Tan S, Berkowitz K, Hodis HN, Azen SP. Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women. Diabetes. 2002 Sep; 51(9):2796-803. View in: PubMed

Sobel BE, Neimane D, Mack WJ, Hodis HN, Buchanan TA. The ratio of plasminogen activator inhibitor type-1 activity to the concentration of plasminogen activator inhibitor type-1 protein in diabetes: adding insult to injury. Coron Artery Dis. 2002 Aug; 13(5):275-81. View in: PubMed

Hodis HN, Mack WJ, Lobo R. Antiatherosclerosis interventions in women. Am J Cardiol. 2002 Jul 3; 90(1A):17F-21F. View in: PubMed

Hodis HN, Mack WJ. Atherosclerosis imaging methods: assessing cardiovascular disease and evaluating the role of estrogen in the prevention of atherosclerosis. Am J Cardiol. 2002 Jun 20; 89(12A):19E-27E; discussion 27E. View in: PubMed

Xiang AH, Azen SP, Buchanan TA, Raffel LJ, Tan S, Cheng LS, Diaz J, Toscano E, Quinonnes M, Liu CR, Liu CH, Castellani LW, Hsueh WA, Rotter JI, Hodis HN. Heritability of subclinical atherosclerosis in Latino families ascertained through a hypertensive parent. Arterioscler Thromb Vasc Biol. 2002 May 1; 22(5):843-8. View in: PubMed

Hodis HN, Mack WJ, Lobo R. Postmenopausal hormone replacement therapy as antiatherosclerotic therapy. Curr Atheroscler Rep. 2002 Jan; 4(1):52-8. View in: PubMed

Hodis HN, Mack WJ, Lobo RA, Shoupe D, Sevanian A, Mahrer PR, Selzer RH, Liu Cr CR, Liu Ch CH, Azen SP. Estrogen in the prevention of atherosclerosis. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2001 Dec 4; 135(11):939-53. View in: PubMed

Slater CC, Zhang C, Hodis HN, Mack WJ, Boostanfar R, Shoupe D, Paulson RJ, Stanczyk FZ. Comparison of estrogen and androgen levels after oral estrogen replacement therapy. J Reprod Med. 2001 Dec; 46(12):1052-6. View in: PubMed

Slater CC, Hodis HN, Mack WJ, Shoupe D, Paulson RJ, Stanczyk FZ. Markedly elevated levels of estrone sulfate after long-term oral, but not transdermal, administration of estradiol in postmenopausal women. Menopause. 2001 May-Jun; 8(3):200-3. View in: PubMed

Xiang AH, Azen SP, Raffel LJ, Tan S, Cheng LS, Diaz J, Toscano E, Henderson PC, Hodis HN, Hsueh WA, Rotter JI, Buchanan TA. Evidence for joint genetic control of insulin sensitivity and systolic blood pressure in hispanic families with a hypertensive proband. Circulation. 2001 Jan 2; 103(1):78-83. View in: PubMed

Selzer RH, Mack WJ, Lee PL, Kwong-Fu H, Hodis HN. Improved common carotid elasticity and intima-media thickness measurements from computer analysis of sequential ultrasound frames. Atherosclerosis. 2001 Jan; 154(1):185-93. View in: PubMed

Hwang J, Hodis HN, Sevanian A. Soy and alfalfa phytoestrogen extracts become potent low-density lipoprotein antioxidants in the presence of acerola cherry extract. J Agric Food Chem. 2001 Jan; 49(1):308-14. View in: PubMed

Dubé MP, Sprecher D, Henry WK, Aberg JA, Torriani FJ, Hodis HN, Schouten J, Levin J, Myers G, Zackin R, Nevin T, Currier JS. Preliminary guidelines for the evaluation and management of dyslipidemia in adults infected with human immunodeficiency virus and receiving antiretroviral therapy: Recommendations of the Adult AIDS Clinical Trial Group Cardiovascular Disease Focus Group. Clin Infect Dis. 2000 Nov; 31(5):1216-24. View in: PubMed

Hodis HN, Hashimoto S, Mack WJ, Sevanian A. Probucol reduces oxysterol formation in hypertensive rabbits. Hypertension. 2000 Sep; 36(3):436-41. View in: PubMed

Mack WJ, Xiang M, Shircore AM, Selzer RH, Hodis HN, Azen SP. Efficacy of two lipid-lowering treatments on quantitative coronary angiographic endpoints. Cardiovasc Drugs Ther. 2000 Aug; 14(4):411-8. View in: PubMed

Hwang J, Sevanian A, Hodis HN, Ursini F. Synergistic inhibition of LDL oxidation by phytoestrogens and ascorbic acid. Free Radic Biol Med. 2000 Jul 1; 29(1):79-89. View in: PubMed

Mack WJ, Xiang M, Selzer RH, Hodis HN. Serial quantitative coronary angiography and coronary events. Am Heart J. 2000 Jun; 139(6):993-9. View in: PubMed

Mack WJ, LaBree L, Liu C, Selzer RH, Hodis HN. Correlations between measures of atherosclerosis change using carotid ultrasonography and coronary angiography. Atherosclerosis. 2000 Jun; 150(2):371-9. View in: PubMed

Hwang J, Peterson H, Hodis HN, Choi B, Sevanian A. Ascorbic acid enhances 17 beta-estradiol-mediated inhibition of oxidized low density lipoprotein formation. Atherosclerosis. 2000 Jun; 150(2):275-84. View in: PubMed

Rong JX, Shen L, Chang YH, Richters A, Hodis HN, Sevanian A. Cholesterol oxidation products induce vascular foam cell lesion formation in hypercholesterolemic New Zealand white rabbits. Arterioscler Thromb Vasc Biol. 1999 Sep; 19(9):2179-88. View in: PubMed

Hodis HN, Mack WJ, Krauss RM, Alaupovic P. Pathophysiology of triglyceride-rich lipoproteins in atherothrombosis: clinical aspects. Clin Cardiol. 1999 Jun; 22(6 Suppl):II15-20. View in: PubMed

Rong JX, Rangaswamy S, Shen L, Dave R, Chang YH, Peterson H, Hodis HN, Chisolm GM, Sevanian A. Arterial injury by cholesterol oxidation products causes endothelial dysfunction and arterial wall cholesterol accumulation. Arterioscler Thromb Vasc Biol. 1998 Dec; 18(12):1885-94. View in: PubMed

Hodis HN, Mack WJ, LaBree L, Selzer RH, Liu CR, Liu CH, Azen SP. The role of carotid arterial intima-media thickness in predicting clinical coronary events. Ann Intern Med. 1998 Feb 15; 128(4):262-9. View in: PubMed

Hodis HN, Mack WJ. Triglyceride-rich lipoproteins and progression of atherosclerosis. Eur Heart J. 1998 Feb; 19 Suppl A:A40-4. View in: PubMed

Hodis HN, Mack WJ, Dunn M, Liu C, Liu C, Selzer RH, Krauss RM. Intermediate-density lipoproteins and progression of carotid arterial wall intima-media thickness. Circulation. 1997 Apr 15; 95(8):2022-6. View in: PubMed

Mack WJ, Azen SP, Dunn M, Hodis HN. A comparison of quantitative computerized and human panel coronary endpoint measures: implications for the design of angiographic trials. Control Clin Trials. 1997 Apr; 18(2):168-79. View in: PubMed

Alaupovic P, Mack WJ, Knight-Gibson C, Hodis HN. The role of triglyceride-rich lipoprotein families in the progression of atherosclerotic lesions as determined by sequential coronary angiography from a controlled clinical trial. Arterioscler Thromb Vasc Biol. 1997 Apr; 17(4):715-22. View in: PubMed

Markus RA, Mack WJ, Azen SP, Hodis HN. Influence of lifestyle modification on atherosclerotic progression determined by ultrasonographic change in the common carotid intima-media thickness. Am J Clin Nutr. 1997 Apr; 65(4):1000-4. View in: PubMed

Wilcox JG, Hwang J, Hodis HN, Sevanian A, Stanczyk FZ, Lobo RA. Cardioprotective effects of individual conjugated equine estrogens through their possible modulation of insulin resistance and oxidation of low-density lipoprotein. Fertil Steril. 1997 Jan; 67(1):57-62. View in: PubMed

Azen SP, Qian D, Mack WJ, Sevanian A, Selzer RH, Liu CR, Liu CH, Hodis HN. Effect of supplementary antioxidant vitamin intake on carotid arterial wall intima-media thickness in a controlled clinical trial of cholesterol lowering. Circulation. 1996 Nov 15; 94(10):2369-72. View in: PubMed

Hodis HN, Mack WJ, Barth J. Carotid intima-media thickness as a surrogate end point for coronary artery disease. Circulation. 1996 Nov 1; 94(9):2311-2. View in: PubMed

Sharma RC, Hodis HN, Mack WJ, Sevanian A, Kramsch DM. Probucol suppresses oxidant stress in hypertensive arteries. Immunohistochemical evidence. Am J Hypertens. 1996 Jun; 9(6):577-90. View in: PubMed

Mack WJ, Krauss RM, Hodis HN. Lipoprotein subclasses in the Monitored Atherosclerosis Regression Study (MARS). Treatment effects and relation to coronary angiographic progression. Arterioscler Thromb Vasc Biol. 1996 May; 16(5):697-704. View in: PubMed

Hodis HN, Mack WJ, LaBree L, Selzer RH, Liu C, Liu C, Alaupovic P, Kwong-Fu H, Azen SP. Reduction in carotid arterial wall thickness using lovastatin and dietary therapy: a randomized controlled clinical trial. Ann Intern Med. 1996 Mar 15; 124(6):548-56. View in: PubMed

Mack WJ, Hodis HN. Efficacy of interventions designed to inhibit the progression of coronary atherosclerosis. Diabetes Res Clin Pract. 1996 Feb; 30 Suppl:37-53. View in: PubMed

Hodis HN. Reversal of atherosclerosis with therapy: update of coronary angiographic trials. Adv Pharmacol. 1996; 35:307-20. View in: PubMed

Azen SP, Mack WJ, Cashin-Hemphill L, LaBree L, Shircore AM, Selzer RH, Blankenhorn DH, Hodis HN. Progression of coronary artery disease predicts clinical coronary events. Long-term follow-up from the Cholesterol Lowering Atherosclerosis Study. Circulation. 1996 Jan 1; 93(1):34-41. View in: PubMed

Shircore AM, Mack WJ, Selzer RH, Lee PL, Azen SP, Alaupovic P, Hodis HN. Compensatory vascular changes of remote coronary segments in response to lesion progression as observed by sequential angiography from a controlled clinical trial. Circulation. 1995 Nov 1; 92(9):2411-8. View in: PubMed

Sevanian A, Hodis HN, Hwang J, McLeod LL, Peterson H. Characterization of endothelial cell injury by cholesterol oxidation products found in oxidized LDL. J Lipid Res. 1995 Sep; 36(9):1971-86. View in: PubMed

Hodis HN, Mack WJ. Triglyceride-rich lipoproteins and the progression of coronary artery disease. Curr Opin Lipidol. 1995 Aug; 6(4):209-14. View in: PubMed

Hodis HN, Mack WJ, LaBree L, Cashin-Hemphill L, Sevanian A, Johnson R, Azen SP. Serial coronary angiographic evidence that antioxidant vitamin intake reduces progression of coronary artery atherosclerosis. JAMA. 1995 Jun 21; 273(23):1849-54. View in: PubMed

Insull W, Davidson MH, Demke DM, Dujovne CA, Eckert SM, Ginsberg D, Goldberg AC, Hodis HN, Hughes TA, Kane JP, et al. The effects of colestipol tablets compared with colestipol granules on plasma cholesterol and other lipids in moderately hypercholesterolemic patients. Atherosclerosis. 1995 Jan 20; 112(2):223-35. View in: PubMed

Hodis HN. Reversibility of atherosclerosis--evolving perspectives from two arterial imaging clinical trials: the cholesterol lowering atherosclerosis regression study and the monitored atherosclerosis regression study. J Cardiovasc Pharmacol. 1995; 25 Suppl 4:S25-31. View in: PubMed

Alaupovic P, Hodis HN, Knight-Gibson C, Mack WJ, LaBree L, Cashin-Hemphill L, Corder CN, Kramsch DM, Blankenhorn DH. Effects of lovastatin on ApoA- and ApoB-containing lipoproteins. Families in a subpopulation of patients participating in the Monitored Atherosclerosis Regression Study (MARS). Arterioscler Thromb. 1994 Dec; 14(12):1906-13. View in: PubMed

Selzer RH, Hodis HN, Kwong-Fu H, Mack WJ, Lee PL, Liu CR, Liu CH. Evaluation of computerized edge tracking for quantifying intima-media thickness of the common carotid artery from B-mode ultrasound images. Atherosclerosis. 1994 Nov; 111(1):1-11. View in: PubMed

Hodis HN, Mack WJ. Risk factor assessment, treatment strategy and prevention of coronary artery disease: the need for a more rational approach. J Intern Med. 1994 Aug; 236(2):111-3. View in: PubMed

Hodis HN, Cashin-Hemphill L, Mack WJ. Prevention of coronary atherosclerosis. Heart Dis Stroke. 1994 Jul-Aug; 3(4):182-7. View in: PubMed

Hodis HN, Mack WJ, Azen SP, Alaupovic P, Pogoda JM, LaBree L, Hemphill LC, Kramsch DM, Blankenhorn DH. Triglyceride- and cholesterol-rich lipoproteins have a differential effect on mild/moderate and severe lesion progression as assessed by quantitative coronary angiography in a controlled trial of lovastatin. Circulation. 1994 Jul; 90(1):42-9. View in: PubMed

Hodis HN, Kramsch DM, Avogaro P, Bittolo-Bon G, Cazzolato G, Hwang J, Peterson H, Sevanian A. Biochemical and cytotoxic characteristics of an in vivo circulating oxidized low density lipoprotein (LDL-). J Lipid Res. 1994 Apr; 35(4):669-77. View in: PubMed

Blankenhorn DH, Hodis HN. George Lyman Duff Memorial Lecture. Arterial imaging and atherosclerosis reversal. Arterioscler Thromb. 1994 Feb; 14(2):177-92. View in: PubMed

Mack WJ, Selzer RH, Hodis HN, Erickson JK, Liu CR, Liu CH, Crawford DW, Blankenhorn DH. One-year reduction and longitudinal analysis of carotid intima-media thickness associated with colestipol/niacin therapy. Stroke. 1993 Dec; 24(12):1779-83. View in: PubMed

Blankenhorn DH, Azen SP, Kramsch DM, Mack WJ, Cashin-Hemphill L, Hodis HN, DeBoer LW, Mahrer PR, Masteller MJ, Vailas LI, Alaupovic P, Hirsch LJ. Coronary angiographic changes with lovastatin therapy. The Monitored Atherosclerosis Regression Study (MARS). Ann Intern Med. 1993 Nov 15; 119(10):969-76. View in: PubMed

Blankenhorn DH, Hodis HN. Atherosclerosis--reversal with therapy. West J Med. 1993 Aug; 159(2):172-9. View in: PubMed

Hodis HN, Quismorio FP, Wickham E, Blankenhorn DH. The lipid, lipoprotein, and apolipoprotein effects of hydroxychloroquine in patients with systemic lupus erythematosus. J Rheumatol. 1993 Apr; 20(4):661-5. View in: PubMed

Hodis HN, Chauhan A, Hashimoto S, Crawford DW, Sevanian A. Probucol reduces plasma and aortic wall oxysterol levels in cholesterol fed rabbits independently of its plasma cholesterol lowering effect. Atherosclerosis. 1992 Oct; 96(2-3):125-34. View in: PubMed

Hodis HN, Crawford DW, Sevanian A. Cholesterol feeding increases plasma and aortic tissue cholesterol oxide levels in parallel: further evidence for the role of cholesterol oxidation in atherosclerosis. Atherosclerosis. 1991 Aug; 89(2-3):117-26. View in: PubMed

Hodis HN, Amartey JK, Crawford DW, Wickham E, Sharma RC, Blankenhorn DH. Relationship of arterial wall uptake of radiolabeled liposomes to the presence of monocyte/macrophage cells in the hypertensive and atherosclerotic arterial wall. Atherosclerosis. 1991 Apr; 87(2-3):109-17. View in: PubMed

Blankenhorn DH, Hodis HN. Treating serum lipid abnormalities in high-priority patients. Postgrad Med. 1991 Jan; 89(1):81-2, 87-90, 93-6. View in: PubMed

Hodis HN. Acute hepatic failure associated with the use of low-dose sustained-release niacin. JAMA. 1990 Jul 11; 264(2):181. View in: PubMed

Hodis HN, Amartey JK, Crawford DW, Wickham E, Blankenhorn DH. In vivo hypertensive arterial wall uptake of radiolabeled liposomes. Hypertension. 1990 Jun; 15(6 Pt 1):600-5. View in: PubMed

Hodis HN, Gordonson JS, Junq RC, Fitzgibbons PL, Sharma OP. Pulmonary masses in a 37 year-old man. Sarcoidosis. 1989 Sep; 6(2):147-52. View in: PubMed

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