Faculty

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Hyungjin Eoh, PhD
Assistant Professor of Molecular Microbiology & Immunology
Molecular Microbiology and Immunology
ZNI 537 1501 San Pablo Health Sciences Campus Los Angeles

Publications

Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2017 Mar 06. View in: PubMed

Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis. ACS Infect Dis. 2016 Oct 5. View in: PubMed

Effects of fluconazole on the metabolomic profile of Candida albicans. J Antimicrob Chemother. 2016 Mar; 71(3):635-40. View in: PubMed

Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis. Cell Rep. 2016 Jan 26; 14(3):572-85. View in: PubMed

Two enzymes with redundant fructose bisphosphatase activity sustain gluconeogenesis and virulence in Mycobacterium tuberculosis. Nat Commun. 2015; 6:7912. View in: PubMed

Metabolomics: a window into the adaptive physiology of Mycobacterium tuberculosis. Tuberculosis (Edinb). 2014 Dec; 94(6):538-43. View in: PubMed

Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis. PLoS Pathog. 2014 May; 10(5):e1004144. View in: PubMed

Allostery and compartmentalization: old but not forgotten. Curr Opin Microbiol. 2014 Apr; 18:23-9. View in: PubMed

Methylcitrate cycle defines the bactericidal essentiality of isocitrate lyase for survival of Mycobacterium tuberculosis on fatty acids. Proc Natl Acad Sci U S A. 2014 Apr 1; 111(13):4976-81. View in: PubMed

Multifunctional essentiality of succinate metabolism in adaptation to hypoxia in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6554-9. View in: PubMed

Co-immunization of plasmid DNA encoding IL-12 and IL-18 with Bacillus Calmette-Guérin vaccine against progressive tuberculosis. Yonsei Med J. 2011 Nov; 52(6):1008-15. View in: PubMed

Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression. PLoS Pathog. 2011 Sep; 7(9):e1002264. View in: PubMed

Expression and validation of D-erythrulose 1-phosphate dehydrogenase from Brucella abortus: a diagnostic reagent for bovine brucellosis. J Vet Diagn Invest. 2010 Jul; 22(4):524-30. View in: PubMed

Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspF. Chem Biol. 2010 Feb 26; 17(2):117-22. View in: PubMed

Regulation of polar peptidoglycan biosynthesis by Wag31 phosphorylation in mycobacteria. BMC Microbiol. 2010; 10:327. View in: PubMed

Expression and characterization of soluble 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from bacterial pathogens. Chem Biol. 2009 Dec 24; 16(12):1230-9. View in: PubMed

The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target. Tuberculosis (Edinb). 2009 Jan; 89(1):1-11. View in: PubMed

Structure-activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase. Bioorg Med Chem Lett. 2008 Oct 1; 18(19):5320-3. View in: PubMed

Chemoenzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol: A substrate for IspE. Tetrahedron Lett. 2008 Jul 21; 49(29-30):4461-4463. View in: PubMed

Characterization of the Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase: potential for drug development. J Bacteriol. 2007 Dec; 189(24):8922-7. View in: PubMed

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