Faculty

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Janice M. Liebler, MD
Professor of Clinical Medicine
Director For County Micu
Medicine
IRD 720 2020 Zonal Avenue Health Sciences Campus Los Angeles
+1 323 442 2290

Overview

Dr. Liebler hails from Detroit, MI where she attended medical school at Wayne State University. After coming to the USC Keck School of Medicine in 1999, Dr. Liebler has established herself as a leading educator in lung transplantation and critical care medicine. She was formally the Associate Medical Director for Keck’s Lung Transplantation Program and is currently an attending physician for both LAC+USC Medical Center’s Medical Intensive Care Unit and Keck Hospital of USC Pulmonary and Critical Care Medicine division. In addition to lung transplantation, Dr. Liebler research interests also include lung injury and repair and cell-based treatment of lung diseases.

Awards

OHSU Foundation: Donor Research Grant, 1992-1999

American Lung Association of Oregon: Research Grant, 1989

Medical Research Foundation of Oregon: Research Grant , 1987

San Jacinto Lung Association: Training Research Grant, 1981

Publications

Region-specific role for Pten in maintenance of epithelial phenotype and integrity. Am J Physiol Lung Cell Mol Physiol. 2017 Jan 01; 312(1):L131-L142. View in: PubMed

Knockout Mice Reveal a Major Role for Alveolar Epithelial Type I Cells in Alveolar Fluid Clearance. Am J Respir Cell Mol Biol. 2016 Sep; 55(3):395-406. View in: PubMed

Combinations of differentiation markers distinguish subpopulations of alveolar epithelial cells in adult lung. Am J Physiol Lung Cell Mol Physiol. 2016 Jan 15; 310(2):L114-20. View in: PubMed

Protocols and Hospital Mortality in Critically Ill Patients: The United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study. Crit Care Med. 2015 Oct; 43(10):2076-84. View in: PubMed

Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis. Am J Respir Cell Mol Biol. 2014 Aug; 51(2):210-22. View in: PubMed

Interactions between ß-catenin and transforming growth factor-ß signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP). J Biol Chem. 2012 Mar 02; 287(10):7026-38. View in: PubMed

Interactions Between ß-Catenin and Transforming Growth Factor-ß Signaling Pathways Mediate Epithelial-Mesenchymal Transition and Are Dependent on the Transcriptional Co-activator cAMP-response Element-binding Protein (CREB)-binding Protein (CBP). J Biol Chem. 2012 Mar 2; 287(10):7026-38. View in: PubMed

Retention of human bone marrow-derived cells in murine lungs following bleomycin-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2008 Aug; 295(2):L285-92. View in: PubMed

Rat aquaporin-5 4. 3-kb 5'-flanking region differentially regulates expression in salivary gland and lung in vivo. Am J Physiol Cell Physiol. 2008 Jul; 295(1):C111-20. View in: PubMed

Developmental pathways and specification of intrapulmonary stem cells. Pediatr Res. 2006 Apr; 59(4 Pt 2):84R-93R. View in: PubMed

Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol. 2005 May; 166(5):1321-32. View in: PubMed

Effects of transdifferentiation and EGF on claudin isoform expression in alveolar epithelial cells. J Appl Physiol. 2005 Jan; 98(1):322-8. View in: PubMed

Alveolar epithelial type I cells express beta2-adrenergic receptors and G-protein receptor kinase 2. J Histochem Cytochem. 2004 Jun; 52(6):759-67. View in: PubMed

Subunit-specific coordinate upregulation of sodium pump activity in alveolar epithelial cells by lentivirus-mediated gene transfer. Hum Gene Ther. 2004 May; 15(5):457-68. View in: PubMed

Foxj1 is required for apical localization of ezrin in airway epithelial cells. J Cell Sci. 2003 Dec 15; 116(Pt 24):4935-45. View in: PubMed

Modulation of ion conductance and active transport by TGF-beta 1 in alveolar epithelial cell monolayers. Am J Physiol Lung Cell Mol Physiol. 2003 Dec; 285(6):L1192-200. View in: PubMed

Identification of three genes of known function expressed by alveolar epithelial type I cells. Am J Respir Cell Mol Biol. 2003 Jul; 29(1):98-105. View in: PubMed

Na transport proteins are expressed by rat alveolar epithelial type I cells. Am J Physiol Lung Cell Mol Physiol. 2002 Apr; 282(4):L599-608. View in: PubMed

Effects of transdifferentiation and EGF on claudin isoform expression in alveolar epithelial cells. J Appl Physiol (1985). 2005 Jan; 98(1):322-8. View in: PubMed

Region-specific role for Pten in maintenance of epithelial phenotype and integrity. Am J Physiol Lung Cell Mol Physiol. 2016 Nov 18; ajplung. 00005. 2015. View in: PubMed

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