Faculty

Back to Index
Jeffrey A Hagen, MD
Associate Professor of Clinical Surgery
Division Chief, Thoracic Surgery
Surgery
HCC 514 Health Sciences Campus Los Angeles
+1 323 442 9066

Overview

Dr. Jeffrey A. Hagen, MD is Chief of the Division of Thoracic Surgery and Director of the General Surgery Residency Program at the Keck School of Medicine of the University of Southern California. He specializes in the field of General Thoracic Surgery, which encompasses benign and malignant diseases of the esophagus, lungs, mediastinum and pleura/chest wall. He has extensive experience in both complex open surgical procedures and in the field of minimally invasive surgery of the chest. The Division of Thoracic Surgery that he leads is nationally and internationally recognized for their experience in esophageal and foregut surgery, contributing hundreds of papers, review articles and book chapters to our knowledge of the field.

He leads the team of surgeons at the Keck Hospital of USC in the rapidly expanding robotic thoracic surgery program using the Da Vinci system. This approach allows the surgeons to perform resections of the lungs (lobectomy) and tumors of the mediastinum (such as thymoma) with greater precision than can be achieved using standard VATS techniques and less discomfort and shorter hospital stays than traditional open surgery. Dr. Hagen also leads the USC Multidisciplinary Lung Cancer Management Program – one of the few programs in the country where a truly multi-specialty clinic exists to efficiently evaluate patients known or suspected to have cancer of the lung. Patients can be simultaneously seen by specialists in Thoracic Surgery, Medical Oncology, Pulmonary Medicine and/or Radiation Oncology to allow us to provide the ultimate in comprehensive and personalized care to our patients.

Dr. Hagen completed his General Surgery training at Creighton University before pursuing specialty training in Esophageal and Foregut Surgery at the University of Southern California under the guidance of Dr. Tom DeMeester. He then obtained his Thoracic Surgery training at the Barnes Hospital - Washington University program in St. Louis before joining the faculty at USC in 1994.

Dr. Hagen’s research interests include assessment of predictors of outcome in the management of cancer of the esophagus and non-small cell cancer of the lung. He is also investigating strategies for early detection of lung cancer using unique DNA methylation signatures for lung cancer developed at USC. He has presented at numerous national and international medical and surgical societies, he serves on the review panels for more than a dozen scientific journals and he has more than 100 peer reviewed publications.

Publications

Dissanayake SN, Hagen J, Fedenko A, Lee C. Calcifying Fibrous Pseudotumor of the Posterior Mediastinum With Encapsulation of the Thoracic Duct. Ann Thorac Surg. 2016 Jul; 102(1):e39-40. View in: PubMed

Boys JA, Alicuben ET, DeMeester MJ, Worrell SG, Oh DS, Hagen JA, DeMeester SR. Public perceptions on robotic surgery, hospitals with robots, and surgeons that use them. Surg Endosc. 2016 Apr; 30(4):1310-6. View in: PubMed

Alnoor M, Boys JA, Worrell SG, Oh DS, Hagen JA, DeMeester SR. Timing and Pattern of Recurrence after Gastrectomy for Adenocarcinoma. Am Surg. 2015 Oct; 81(10):1057-60. View in: PubMed

Boys JA, Oh DS, Lewis JS, DeMeester SR, Hagen JA. Esophageal Adenocarcinoma in Patients Younger than 40 Years: A Two-Decade Experience at a Public and Private Hospital. Am Surg. 2015 Oct; 81(10):974-8. View in: PubMed

Greene CL, McFadden PM, Oh DS, Chang EJ, Hagen JA. Long-Term Outcome of the Treatment of Zenker's Diverticulum. Ann Thorac Surg. 2015 Sep; 100(3):975-8. View in: PubMed

Zehetner J, DeMeester SR, Alicuben ET, Oh DS, Lipham JC, Hagen JA, DeMeester TR. Intraoperative Assessment of Perfusion of the Gastric Graft and Correlation With Anastomotic Leaks After Esophagectomy. Ann Surg. 2015 Jul; 262(1):74-8. View in: PubMed

Greene CL, Chang EJ, Oh DS, Worrell SG, Hagen JA, DeMeester SR. High resolution manometry sub-classification of Achalasia: does it really matter? Surg Endosc. 2015 Jun; 29(6):1363-7. View in: PubMed

Hagen JA. Diffusion-weighted magnetic resonance imaging may identify candidates for alternatives to lobectomy for early stage lung cancer. J Thorac Cardiovasc Surg. 2015 Apr; 149(4):997. View in: PubMed

Greene CL, DeMeester SR, Augustin F, Worrell SG, Oh DS, Hagen JA, DeMeester TR. Long-term quality of life and alimentary satisfaction after esophagectomy with colon interposition. Ann Thorac Surg. 2014 Nov; 98(5):1713-20. View in: PubMed

Worrell SG, Oh DS, Greene CL, DeMeester SR, Hagen JA. Acute esophageal necrosis: a case series and long-term follow-up. Ann Thorac Surg. 2014 Jul; 98(1):341-2. View in: PubMed

Hagen JA. Invited commentary. Ann Thorac Surg. 2014 Jun; 97(6):1973-4. View in: PubMed

Greene CL, Demeester SR, Worrell SG, Oh DS, Hagen JA, Demeester TR. Alimentary satisfaction, gastrointestinal symptoms, and quality of life 10 or more years after esophagectomy with gastric pull-up. J Thorac Cardiovasc Surg. 2014 Mar; 147(3):909-14. View in: PubMed

Worrell SG, Oh DS, Greene CL, Demeester SR, Hagen JA. Endoscopic ultrasound staging of stenotic esophageal cancers may be unnecessary to determine the need for neoadjuvant therapy. J Gastrointest Surg. 2014 Feb; 18(2):318-20. View in: PubMed

Greene CL, Demeester SR, Zehetner J, Worrell SG, Oh DS, Hagen JA. Diaphragmatic relaxing incisions during laparoscopic paraesophageal hernia repair. Surg Endosc. 2013 Dec; 27(12):4532-8. View in: PubMed

Worrell SG, DeMeester SR, Greene CL, Oh DS, Hagen JA. Pharyngeal pH monitoring better predicts a successful outcome for extraesophageal reflux symptoms after antireflux surgery. Surg Endosc. 2013 Nov; 27(11):4113-8. View in: PubMed

Oh DS, Cho I, Karamian B, DeMeester SR, Hagen JA. Early adoption of robotic pulmonary lobectomy: feasibility and initial outcomes. Am Surg. 2013 Oct; 79(10):1075-80. View in: PubMed

Grant KS, DeMeester SR, Kreger V, Oh D, Hagen JA, Chandrasoma P, DeMeester TR. Effect of Barrett's esophagus surveillance on esophageal preservation, tumor stage, and survival with esophageal adenocarcinoma. J Thorac Cardiovasc Surg. 2013 Jul; 146(1):31-7. View in: PubMed

Oezcelik A, Ayazi S, DeMeester SR, Zehetner J, Abate E, Dunn J, Grant KS, Lipham JC, Hagen JA, DeMeester TR. Adenocarcinoma of the esophagus in the young. J Gastrointest Surg. 2013 Jun; 17(6):1032-5. View in: PubMed

Hagen JA. Invited commentary. Ann Thorac Surg. 2013 Feb; 95(2):463-4. View in: PubMed

Selamat SA, Chung BS, Girard L, Zhang W, Zhang Y, Campan M, Siegmund KD, Koss MN, Hagen JA, Lam WL, Lam S, Gazdar AF, Laird-Offringa IA. Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression. Genome Res. 2012 Jul; 22(7):1197-211. View in: PubMed

Hagen JA. Invited commentary. Ann Thorac Surg. 2012 Jun; 93(6):1854. View in: PubMed

Theodorou D, Ayazi S, Demeester SR, Zehetner J, Peyre CG, Grant KS, Augustin F, Oh DS, Lipham JC, Chandrasoma PT, Hagen JA, Demeester TR. Intraluminal pH and Goblet Cell Density in Barrett's Esophagus. J Gastrointest Surg. 2012 Mar; 16(3):469-74. View in: PubMed

Chandrasoma P, Wijetunge S, Demeester S, Ma Y, Hagen J, Zamis L, Demeester T. Columnar-lined esophagus without intestinal metaplasia has no proven risk of adenocarcinoma. Am J Surg Pathol. 2012 Jan; 36(1):1-7. View in: PubMed

Hagen JA. Invited commentary. Ann Thorac Surg. 2011 Dec; 92(6):2027. View in: PubMed

Chandrasoma P, Wijetunge S, Ma Y, Demeester S, Hagen J, Demeester T. The dilated distal esophagus: a new entity that is the pathologic basis of early gastroesophageal reflux disease. Am J Surg Pathol. 2011 Dec; 35(12):1873-81. View in: PubMed

Ayazi S, Hagen JA, Zehetner J, Banki F, Augustin F, Ayazi A, DeMeester SR, Oh DS, Sohn HJ, Lipham JC, DeMeester TR. Day-to-day discrepancy in Bravo pH monitoring is related to the degree of deterioration of the lower esophageal sphincter and severity of reflux disease. Surg Endosc. 2011 Jul; 25(7):2219-23. View in: PubMed

Ayazi S, DeMeester SR, Hsieh CC, Zehetner J, Sharma G, Grant KS, Oh DS, Lipham JC, Hagen JA, DeMeester TR. Thoraco-abdominal pressure gradients during the phases of respiration contribute to gastroesophageal reflux disease. Dig Dis Sci. 2011 Jun; 56(6):1718-22. View in: PubMed

Zehetner J, Demeester SR, Ayazi S, Kilday P, Augustin F, Hagen JA, Lipham JC, Sohn HJ, Demeester TR. Laparoscopic versus open repair of paraesophageal hernia: the second decade. J Am Coll Surg. 2011 May; 212(5):813-20. View in: PubMed

Leers JM, DeMeester SR, Oezcelik A, Klipfel N, Ayazi S, Abate E, Zehetner J, Lipham JC, Chan L, Hagen JA, DeMeester TR. The prevalence of lymph node metastases in patients with T1 esophageal adenocarcinoma a retrospective review of esophagectomy specimens. Ann Surg. 2011 Feb; 253(2):271-8. View in: PubMed

Zehetner J, DeMeester SR, Hagen JA, Ayazi S, Augustin F, Lipham JC, DeMeester TR. Endoscopic resection and ablation versus esophagectomy for high-grade dysplasia and intramucosal adenocarcinoma. J Thorac Cardiovasc Surg. 2011 Jan; 141(1):39-47. View in: PubMed

Hagen JA. Invited commentary. Ann Thorac Surg. 2010 Nov; 90(5):1667-8. View in: PubMed

Ayazi S, Hagen JA, Zehetner J, Lilley M, Wali P, Augustin F, Oezcelik A, Sohn HJ, Lipham JC, Demeester SR, DeMeester TR. Loss of alkalization in proximal esophagus: a new diagnostic paradigm for patients with laryngopharyngeal reflux. J Gastrointest Surg. 2010 Nov; 14(11):1653-9. View in: PubMed

Chandrasoma P, Wijetunge S, Demeester SR, Hagen J, Demeester TR. The histologic squamo-oxyntic gap: an accurate and reproducible diagnostic marker of gastroesophageal reflux disease. Am J Surg Pathol. 2010 Nov; 34(11):1574-81. View in: PubMed

Zehetner J, DeMeester SR, Ayazi S, Costales JL, Augustin F, Oezcelik A, Lipham JC, Sohn HJ, Hagen JA, DeMeester TR. Long-term follow-up after anti-reflux surgery in patients with Barrett's esophagus. J Gastrointest Surg. 2010 Oct; 14(10):1483-91. View in: PubMed

Wijetunge S, Ma Y, DeMeester S, Hagen J, DeMeester T, Chandrasoma P. Association of adenocarcinomas of the distal esophagus, "gastroesophageal junction," and "gastric cardia" with gastric pathology. Am J Surg Pathol. 2010 Oct; 34(10):1521-7. View in: PubMed

Oezcelik A, Banki F, Ayazi S, Abate E, Zehetner J, Sohn HJ, Hagen JA, DeMeester SR, Lipham JC, Palmer SL, DeMeester TR. Detection of gastric conduit ischemia or anastomotic breakdown after cervical esophagogastrostomy: the use of computed tomography scan versus early endoscopy. Surg Endosc. 2010 Aug; 24(8):1948-51. View in: PubMed

Ayazi S, Tamhankar A, DeMeester SR, Zehetner J, Wu C, Lipham JC, Hagen JA, DeMeester TR. The impact of gastric distension on the lower esophageal sphincter and its exposure to acid gastric juice. Ann Surg. 2010 Jul; 252(1):57-62. View in: PubMed

Lurje G, Leers JM, Pohl A, Oezcelik A, Zhang W, Ayazi S, Winder T, Ning Y, Yang D, Klipfel NE, Chandrasoma P, Hagen JA, DeMeester SR, DeMeester TR, Lenz HJ. Genetic variations in angiogenesis pathway genes predict tumor recurrence in localized adenocarcinoma of the esophagus. Ann Surg. 2010 May; 251(5):857-64. View in: PubMed

Ayazi S, Hagen JA, Chandrasoma P, Gholami P, Zehetner J, Oezcelik A, Lipham JC, Demeester SR, Demeester TR, Kline MM. Esophageal intraepithelial eosinophils in dysphagic patients with gastroesophageal reflux disease. Dig Dis Sci. 2010 Apr; 55(4):967-72. View in: PubMed

Abate E, DeMeester SR, Zehetner J, Oezcelik A, Ayazi S, Costales J, Banki F, Lipham JC, Hagen JA, DeMeester TR. Recurrence after esophagectomy for adenocarcinoma: defining optimal follow-up intervals and testing. J Am Coll Surg. 2010 Apr; 210(4):428-35. View in: PubMed

Banki F, Flanagan P, Zehetner J, Armstrong A, Hagen JA, Joshi A, Sinha R, Oh D, Oezcelik A, DeMeester SR, Abate E, Lipham JC, Chandrasoma P, Crookes PF, DeMeester TR. Progressive mucosal injury in patients with gastroesophageal reflux disease and increasing peripheral blood eosinophil counts. Arch Surg. 2010 Apr; 145(4):363-6. View in: PubMed

Ayazi S, Hagen JA, Zehetner J, Oezcelik A, Abate E, Kohn GP, Sohn HJ, Lipham JC, Demeester SR, Demeester TR. Proximal esophageal pH monitoring: improved definition of normal values and determination of a composite pH score. J Am Coll Surg. 2010 Mar; 210(3):345-50. View in: PubMed

Zehetner J, Lipham JC, Ayazi S, Oezcelik A, Abate E, Chen W, Demeester SR, Sohn HJ, Banki F, Hagen JA, Dickey M, Demeester TR. A simplified technique for intrathoracic stomach repair: laparoscopic fundoplication with Vicryl mesh and BioGlue crural reinforcement. Surg Endosc. 2010 Mar; 24(3):675-9. View in: PubMed

Peyré SE, Peyré CG, Hagen JA, Sullivan ME. Reliability of a procedural checklist as a high-stakes measurement of advanced technical skill. Am J Surg. 2010 Jan; 199(1):110-4. View in: PubMed

Ayazi S, Hagen JA, Zehetner J, Ross O, Wu C, Oezcelik A, Abate E, Sohn HJ, Banki F, Lipham JC, DeMeester SR, Demeester TR. The value of high-resolution manometry in the assessment of the resting characteristics of the lower esophageal sphincter. J Gastrointest Surg. 2009 Dec; 13(12):2113-20. View in: PubMed

Leers JM, DeMeester SR, Chan N, Ayazi S, Oezcelik A, Abate E, Banki F, Lipham JC, Hagen JA, DeMeester TR. Clinical characteristics, biologic behavior, and survival after esophagectomy are similar for adenocarcinoma of the gastroesophageal junction and the distal esophagus. J Thorac Cardiovasc Surg. 2009 Sep; 138(3):594-602; discussion 601-2. View in: PubMed

Ayazi S, Leers JM, Oezcelik A, Abate E, Peyre CG, Hagen JA, DeMeester SR, Banki F, Lipham JC, DeMeester TR, Crookes PF. Measurement of gastric pH in ambulatory esophageal pH monitoring. Surg Endosc. 2009 Sep; 23(9):1968-73. View in: PubMed

Ayazi S, Hagen JA, Chan LS, DeMeester SR, Lin MW, Ayazi A, Leers JM, Oezcelik A, Banki F, Lipham JC, DeMeester TR, Crookes PF. Obesity and gastroesophageal reflux: quantifying the association between body mass index, esophageal acid exposure, and lower esophageal sphincter status in a large series of patients with reflux symptoms. J Gastrointest Surg. 2009 Aug; 13(8):1440-7. View in: PubMed

Abate E, Banki F, Hagen JA, Klipfel N. Giant cell tumor of the sternum. Ann Thorac Surg. 2009 Aug; 88(2):645-7. View in: PubMed

Oezcelik A, Banki F, DeMeester SR, Leers JM, Ayazi S, Abate E, Hagen JA, Lipham JC, DeMeester TR. Delayed esophagogastrostomy: a safe strategy for management of patients with ischemic gastric conduit at time of esophagectomy. J Am Coll Surg. 2009 Jun; 208(6):1030-4. View in: PubMed

Oh DS, DeMeester SR, Dunst CM, Mori R, Lehman BJ, Kuramochi H, Danenberg K, Danenberg P, Hagen JA, Chandrasoma P, DeMeester TR. Validation of a rodent model of Barrett's esophagus using quantitative gene expression profiling. Surg Endosc. 2009 Jun; 23(6):1346-52. View in: PubMed

Peyre SE, Peyre CG, Hagen JA, Sullivan ME, Lipham JC, Demeester SR, Peters JH, Demeester TR. Laparoscopic Nissen fundoplication assessment: task analysis as a model for the development of a procedural checklist. Surg Endosc. 2009 Jun; 23(6):1227-32. View in: PubMed

Leers JM, Ayazi S, Hagen JA, Terterov S, Klipfel N, Oezcelik A, Abate E, Lipham JC, DeMeester SR, Banki F, DeMeester TR. Survival in lymph node negative adenocarcinoma of the esophagus after R0 resection with and without neoadjuvant therapy: evidence for downstaging of N status. J Am Coll Surg. 2009 Apr; 208(4):553-6. View in: PubMed

Lord RV, DeMeester SR, Peters JH, Hagen JA, Elyssnia D, Sheth CT, DeMeester TR. Hiatal hernia, lower esophageal sphincter incompetence, and effectiveness of Nissen fundoplication in the spectrum of gastroesophageal reflux disease. J Gastrointest Surg. 2009 Apr; 13(4):602-10. View in: PubMed

Chiu PW, Ayazi S, Hagen JA, Lipham JC, Zehetner J, Abate E, Oezcelik A, Hsieh CC, DeMeester SR, Banki F, Chandrasoma P, DeMeester TR. Esophageal pH exposure and epithelial cell differentiation. Dis Esophagus. 2009; 22(7):596-9. View in: PubMed

Ayazi S, Lipham JC, Portale G, Peyre CG, Streets CG, Leers JM, Demeester SR, Banki F, Chan LS, Hagen JA, Demeester TR. Bravo catheter-free pH monitoring: normal values, concordance, optimal diagnostic thresholds, and accuracy. Clin Gastroenterol Hepatol. 2009 Jan; 7(1):60-7. View in: PubMed

Oezcelik A, Hagen JA, Halls JM, Leers JM, Abate E, Ayazi S, Zehetner J, DeMeester SR, Banki F, Lipham JC, DeMeester TR. An improved method of assessing esophageal emptying using the timed barium study following surgical myotomy for achalasia. J Gastrointest Surg. 2009 Jan; 13(1):14-8. View in: PubMed

Peyre CG, Hagen JA, DeMeester SR, Van Lanschot JJ, Hölscher A, Law S, Ruol A, Ancona E, Griffin SM, Altorki NK, Rice TW, Wong J, Lerut T, DeMeester TR. Predicting systemic disease in patients with esophageal cancer after esophagectomy: a multinational study on the significance of the number of involved lymph nodes. Ann Surg. 2008 Dec; 248(6):979-85. View in: PubMed

Peyre CG, Hagen JA, DeMeester SR, Altorki NK, Ancona E, Griffin SM, Hölscher A, Lerut T, Law S, Rice TW, Ruol A, van Lanschot JJ, Wong J, DeMeester TR. The number of lymph nodes removed predicts survival in esophageal cancer: an international study on the impact of extent of surgical resection. Ann Surg. 2008 Oct; 248(4):549-56. View in: PubMed

Banki F, Yacoub WN, Hagen JA, Mason RJ, Ayazi S, DeMeester SR, Lipham JC, Danenberg K, Danenberg P, DeMeester TR. Plasma DNA is more reliable than carcinoembryonic antigen for diagnosis of recurrent esophageal cancer. J Am Coll Surg. 2008 Jul; 207(1):30-5. View in: PubMed

Rodrigo S, Abboud G, Oh D, DeMeester SR, Hagen J, Lipham J, DeMeester TR, Chandrasoma P. High intraepithelial eosinophil counts in esophageal squamous epithelium are not specific for eosinophilic esophagitis in adults. Am J Gastroenterol. 2008 Feb; 103(2):435-42. View in: PubMed

Anglim PP, Galler JS, Koss MN, Hagen JA, Turla S, Campan M, Weisenberger DJ, Laird PW, Siegmund KD, Laird-Offringa IA. Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer. Mol Cancer. 2008; 7:62. View in: PubMed

Peyre CG, DeMeester SR, Rizzetto C, Bansal N, Tang AL, Ayazi S, Leers JM, Lipham JC, Hagen JA, DeMeester TR. Vagal-sparing esophagectomy: the ideal operation for intramucosal adenocarcinoma and barrett with high-grade dysplasia. Ann Surg. 2007 Oct; 246(4):665-71; discussion 671-4. View in: PubMed

Oh DS, DeMeester SR, Vallbohmer D, Mori R, Kuramochi H, Hagen JA, Lipham J, Danenberg KD, Danenberg PV, Chandrasoma P, DeMeester TR. Reduction of interleukin 8 gene expression in reflux esophagitis and Barrett's esophagus with antireflux surgery. Arch Surg. 2007 Jun; 142(6):554-9; discussion 559-60. View in: PubMed

Banki F, Mason RJ, Oh D, Hagen JA, DeMeester SR, Lipham JC, Tanaka K, Danenberg KD, Yacoub WN, Danenberg PV, DeMeester TR. Plasma DNA as a molecular marker for completeness of resection and recurrent disease in patients with esophageal cancer. Arch Surg. 2007 Jun; 142(6):533-8; discussion 538-9. View in: PubMed

Kerr KM, Galler JS, Hagen JA, Laird PW, Laird-Offringa IA. The role of DNA methylation in the development and progression of lung adenocarcinoma. Dis Markers. 2007; 23(1-2):5-30. View in: PubMed

Tsou JA, Galler JS, Siegmund KD, Laird PW, Turla S, Cozen W, Hagen JA, Koss MN, Laird-Offringa IA. Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma. Mol Cancer. 2007; 6:70. View in: PubMed

Kanaan S, Boswell WD, Hagen JA. Clinical and radiographic signs lead to early detection of lobar torsion and subsequent successful intervention. J Thorac Cardiovasc Surg. 2006 Sep; 132(3):720-1. View in: PubMed

Oh DS, Hagen JA, Chandrasoma PT, Dunst CM, Demeester SR, Alavi M, Bremner CG, Lipham J, Rizzetto C, Cote R, Demeester TR. Clinical biology and surgical therapy of intramucosal adenocarcinoma of the esophagus. J Am Coll Surg. 2006 Aug; 203(2):152-61. View in: PubMed

Vallböhmer D, DeMeester SR, Oh DS, Banki F, Kuramochi H, Shimizu D, Hagen JA, Danenberg KD, Danenberg PV, Chandrasoma PT, Peters JH, DeMeester TR. Antireflux surgery normalizes cyclooxygenase-2 expression in squamous epithelium of the distal esophagus. Am J Gastroenterol. 2006 Jul; 101(7):1458-66. View in: PubMed

Oh DS, Hagen JA, Fein M, Bremner CG, Dunst CM, Demeester SR, Lipham J, Demeester TR. The impact of reflux composition on mucosal injury and esophageal function. J Gastrointest Surg. 2006 Jun; 10(6):787-96; discussion 796-7. View in: PubMed

Hamoui N, Lord RV, Hagen JA, Theisen J, Demeester TR, Crookes PF. Response of the lower esophageal sphincter to gastric distention by carbonated beverages. J Gastrointest Surg. 2006 Jun; 10(6):870-7. View in: PubMed

Vallböhmer D, Peters JH, Kuramochi H, Oh D, Yang D, Shimizu D, DeMeester SR, Hagen JA, Chandrasoma PT, Danenberg KD, Danenberg PV, DeMeester TR. Molecular determinants in targeted therapy for esophageal adenocarcinoma. Arch Surg. 2006 May; 141(5):476-81; discussion 481-2. View in: PubMed

Heestand G, Morrison B, Correa A, Palmer S, Mateo R, Hagen J, Genyk Y, Selby R, Sher L. Gallstone-induced inflammatory fibrosis: a relentless clinical course of retained gallstones after laparoscopic cholecystectomy. Am Surg. 2006 Apr; 72(4):303-6. View in: PubMed

Portale G, Hagen JA, Peters JH, Chan LS, DeMeester SR, Gandamihardja TA, DeMeester TR. Modern 5-year survival of resectable esophageal adenocarcinoma: single institution experience with 263 patients. J Am Coll Surg. 2006 Apr; 202(4):588-96; discussion 596-8. View in: PubMed

Vallböhmer D, Peters JH, Oh D, Kuramochi H, Shimizu D, Demeester SR, Hagen JA, Chandrasoma PT, Danenberg KD, DeMeester TR, Danenberg P. Survivin, a potential biomarker in the development of Barrett's adenocarcinoma. Surgery. 2005 Oct; 138(4):701-6; discussion 706-7. View in: PubMed

Portale G, Peters JH, Hagen JA, Demeester SR, Gandamihardja TA, Tharavej C, Hsieh CC, Demeester TR. Comparison of the clinical and histological characteristics and survival of distal esophageal-gastroesophageal junction adenocarcinoma in patients with and without barrett mucosa. Arch Surg. 2005 Jun; 140(6):570-4; discussion 574-5. View in: PubMed

Banki F, Demeester SR, Mason RJ, Campos G, Hagen JA, Peters JH, Bremner CG, Demeester TR. Barrett's esophagus in females: a comparative analysis of risk factors in females and males. Am J Gastroenterol. 2005 Mar; 100(3):560-7. View in: PubMed

Tsou JA, Shen LY, Siegmund KD, Long TI, Laird PW, Seneviratne CK, Koss MN, Pass HI, Hagen JA, Laird-Offringa IA. Distinct DNA methylation profiles in malignant mesothelioma, lung adenocarcinoma, and non-tumor lung. Lung Cancer. 2005 Feb; 47(2):193-204. View in: PubMed

Theisen J, Peters JH, Fein M, Hughes M, Hagen JA, Demeester SR, Demeester TR, Laird PW. The mutagenic potential of duodenoesophageal reflux. Ann Surg. 2005 Jan; 241(1):63-8. View in: PubMed

Tamhankar AP, Peters JH, Portale G, Hsieh CC, Hagen JA, Bremner CG, DeMeester TR. Omeprazole does not reduce gastroesophageal reflux: new insights using multichannel intraluminal impedance technology. J Gastrointest Surg. 2004 Nov; 8(7):890-7; discussion 897-8. View in: PubMed

Waterman TA, Hagen JA, Peters JH, DeMeester SR, Taylor CR, Demeester TR. The prognostic importance of immunohistochemically detected node metastases in resected esophageal adenocarcinoma. Ann Thorac Surg. 2004 Oct; 78(4):1161-9; discussion 1161-9. View in: PubMed

Hamoui N, Peters JH, Schneider S, Uchida K, Yang D, Vallböhmer D, Valboehmer D, Hagen JA, DeMeester SR, DeMeester TR, Danenberg K, Danenberg P. Increased acid exposure in patients with gastroesophageal reflux disease influences cyclooxygenase-2 gene expression in the squamous epithelium of the lower esophagus. Arch Surg. 2004 Jul; 139(7):712-6; discussion 716-7. View in: PubMed

Johansson J, DeMeester TR, Hagen JA, DeMeester SR, Peters JH, Oberg S, Bremner CG. En bloc vs transhiatal esophagectomy for stage T3 N1 adenocarcinoma of the distal esophagus. Arch Surg. 2004 Jun; 139(6):627-31; discussion 631-3. View in: PubMed

Briel JW, Tamhankar AP, Hagen JA, DeMeester SR, Johansson J, Choustoulakis E, Peters JH, Bremner CG, DeMeester TR. Prevalence and risk factors for ischemia, leak, and stricture of esophageal anastomosis: gastric pull-up versus colon interposition. J Am Coll Surg. 2004 Apr; 198(4):536-41; discussion 541-2. View in: PubMed

Arain MA, Peters JH, Tamhankar AP, Portale G, Almogy G, DeMeester SR, Crookes PF, Hagen JA, Bremner CG, DeMeester TR. Preoperative lower esophageal sphincter pressure affects outcome of laparoscopic esophageal myotomy for achalasia. J Gastrointest Surg. 2004 Mar-Apr; 8(3):328-34. View in: PubMed

Peters JH, Hagen JA, DeMeester SR. Barrett's esophagus. J Gastrointest Surg. 2004 Jan; 8(1):1-17. View in: PubMed

Tamhankar AP, Almogy G, Arain MA, Portale G, Hagen JA, Peters JH, Crookes PF, Sillin LF, DeMeester SR, Bremner CG, DeMeester TR. Surgical management of hypertensive lower esophageal sphincter with dysphagia or chest pain. J Gastrointest Surg. 2003 Dec; 7(8):990-6; discussion 996. View in: PubMed

Campos GM, Oberg S, Gastal O, Theisen J, Nigro JJ, Hagen JA, Costantini M, Bremner CG, DeMeester TR, Crookes PF. Manometry of the lower esophageal sphincter: inter- and intraindividual variability of slow motorized pull-through versus station pull-through manometry. Dig Dis Sci. 2003 Jun; 48(6):1057-61. View in: PubMed

Gurski RR, Peters JH, Hagen JA, DeMeester SR, Bremner CG, Chandrasoma PT, DeMeester TR. Barrett's esophagus can and does regress after antireflux surgery: a study of prevalence and predictive features. J Am Coll Surg. 2003 May; 196(5):706-12; discussion 712-3. View in: PubMed

Hagen JA, DeMeester TR. Staging of esophageal carcinoma. J Thorac Cardiovasc Surg. 2003 May; 125(5):988-91. View in: PubMed

Streets CG, DeMeester SR, DeMeester TR, Peters JH, Hagen JA, Crookes PF, Bremner CG. Excellent quality of life after Nissen fundoplication depends on successful elimination of reflux symptoms and not the invasiveness of the surgical approach. Ann Thorac Surg. 2002 Oct; 74(4):1019-24; discussion 1024-5. View in: PubMed

DeMeester SR, Wickramasinghe KS, Lord RV, Friedman A, Balaji NS, Chandrasoma PT, Hagen JA, Peters JH, DeMeester TR. Cytokeratin and DAS-1 immunostaining reveal similarities among cardiac mucosa, CIM, and Barrett's esophagus. Am J Gastroenterol. 2002 Oct; 97(10):2514-23. View in: PubMed

Banki F, Mason RJ, DeMeester SR, Hagen JA, Balaji NS, Crookes PF, Bremner CG, Peters JH, DeMeester TR. Vagal-sparing esophagectomy: a more physiologic alternative. Ann Surg. 2002 Sep; 236(3):324-35; discussion 335-6. View in: PubMed

Tsou JA, Hagen JA, Carpenter CL, Laird-Offringa IA. DNA methylation analysis: a powerful new tool for lung cancer diagnosis. Oncogene. 2002 Aug 12; 21(35):5450-61. View in: PubMed

Balaji NS, Crookes PF, Banki F, Hagen JA, Ardill JE, DeMeester TR. A safe and noninvasive test for vagal integrity revisited. Arch Surg. 2002 Aug; 137(8):954-8; discussion 958-9. View in: PubMed

Lord RV, Kaminski A, Oberg S, Bowrey DJ, Hagen JA, DeMeester SR, Sillin LF, Peters JH, Crookes PF, DeMeester TR. Absence of gastroesophageal reflux disease in a majority of patients taking acid suppression medications after Nissen fundoplication. J Gastrointest Surg. 2002 Jan-Feb; 6(1):3-9; discussion 10. View in: PubMed

Powered bySC CTSI