Faculty

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Jeffrey A Hagen, MD
Associate Professor of Clinical Surgery
Surgery
HCC 514 Health Sciences Campus Los Angeles
+1 323 442 9066

Overview

Dr. Jeffrey A. Hagen, MD is Director of the General Surgery Residency Program at the Keck School of Medicine of the University of Southern California. He specializes in the field of General Thoracic Surgery, which encompasses benign and malignant diseases of the esophagus, lungs, mediastinum and pleura/chest wall. He has extensive experience in both complex open surgical procedures and in the field of minimally invasive surgery of the chest. The Division of Thoracic Surgery that he leads is nationally and internationally recognized for their experience in esophageal and foregut surgery, contributing hundreds of papers, review articles and book chapters to our knowledge of the field.

He leads the team of surgeons at the Keck Hospital of USC in the rapidly expanding robotic thoracic surgery program using the Da Vinci system. This approach allows the surgeons to perform resections of the lungs (lobectomy) and tumors of the mediastinum (such as thymoma) with greater precision than can be achieved using standard VATS techniques and less discomfort and shorter hospital stays than traditional open surgery. Dr. Hagen also leads the USC Multidisciplinary Lung Cancer Management Program – one of the few programs in the country where a truly multi-specialty clinic exists to efficiently evaluate patients known or suspected to have cancer of the lung. Patients can be simultaneously seen by specialists in Thoracic Surgery, Medical Oncology, Pulmonary Medicine and/or Radiation Oncology to allow us to provide the ultimate in comprehensive and personalized care to our patients.

Dr. Hagen completed his General Surgery training at Creighton University before pursuing specialty training in Esophageal and Foregut Surgery at the University of Southern California under the guidance of Dr. Tom DeMeester. He then obtained his Thoracic Surgery training at the Barnes Hospital - Washington University program in St. Louis before joining the faculty at USC in 1994.

Dr. Hagen’s research interests include assessment of predictors of outcome in the management of cancer of the esophagus and non-small cell cancer of the lung. He is also investigating strategies for early detection of lung cancer using unique DNA methylation signatures for lung cancer developed at USC. He has presented at numerous national and international medical and surgical societies, he serves on the review panels for more than a dozen scientific journals and he has more than 100 peer reviewed publications.

Publications

Accuracy of Clinical Staging and Outcome With Primary Resection for Local-Regionally Limited Esophageal Adenocarcinoma. Ann Surg. 2017 Feb 01. View in: PubMed

Post-Nissen Dysphagia and Bloating Syndrome: Outcomes After Conversion to Toupet Fundoplication. J Gastrointest Surg. 2016 Nov 10. View in: PubMed

Calcifying Fibrous Pseudotumor of the Posterior Mediastinum With Encapsulation of the Thoracic Duct. Ann Thorac Surg. 2016 Jul; 102(1):e39-40. View in: PubMed

Public perceptions on robotic surgery, hospitals with robots, and surgeons that use them. Surg Endosc. 2016 Apr; 30(4):1310-6. View in: PubMed

Timing and Pattern of Recurrence after Gastrectomy for Adenocarcinoma. Am Surg. 2015 Oct; 81(10):1057-60. View in: PubMed

Esophageal Adenocarcinoma in Patients Younger than 40 Years: A Two-Decade Experience at a Public and Private Hospital. Am Surg. 2015 Oct; 81(10):974-8. View in: PubMed

Long-Term Outcome of the Treatment of Zenker's Diverticulum. Ann Thorac Surg. 2015 Sep; 100(3):975-8. View in: PubMed

Intraoperative Assessment of Perfusion of the Gastric Graft and Correlation With Anastomotic Leaks After Esophagectomy. Ann Surg. 2015 Jul; 262(1):74-8. View in: PubMed

High resolution manometry sub-classification of Achalasia: does it really matter? : Does Achalasia sub-classification matter? Surg Endosc. High resolution manometry sub-classification of Achalasia: does it really matter? Surg Endosc. 2015 Jun; 29(6):1363-7. View in: PubMed

Diffusion-weighted magnetic resonance imaging may identify candidates for alternatives to lobectomy for early stage lung cancer. J Thorac Cardiovasc Surg. 2015 Apr; 149(4):997. View in: PubMed

Long-term quality of life and alimentary satisfaction after esophagectomy with colon interposition. Ann Thorac Surg. 2014 Nov; 98(5):1713-20. View in: PubMed

RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 degradation and promoting apoptosis. Oncogene. 2014 Jul 3; 33(27):3604-11. View in: PubMed

Acute esophageal necrosis: a case series and long-term follow-up. Ann Thorac Surg. 2014 Jul; 98(1):341-2. View in: PubMed

Invited commentary. Ann Thorac Surg. 2014 Jun; 97(6):1973-4. View in: PubMed

Alimentary satisfaction, gastrointestinal symptoms, and quality of life 10 or more years after esophagectomy with gastric pull-up. J Thorac Cardiovasc Surg. 2014 Mar; 147(3):909-14. View in: PubMed

Endoscopic ultrasound staging of stenotic esophageal cancers may be unnecessary to determine the need for neoadjuvant therapy. J Gastrointest Surg. 2014 Feb; 18(2):318-20. View in: PubMed

Diaphragmatic relaxing incisions during laparoscopic paraesophageal hernia repair. Surg Endosc. 2013 Dec; 27(12):4532-8. View in: PubMed

Pharyngeal pH monitoring better predicts a successful outcome for extraesophageal reflux symptoms after antireflux surgery. Surg Endosc. 2013 Nov; 27(11):4113-8. View in: PubMed

Early adoption of robotic pulmonary lobectomy: feasibility and initial outcomes. Am Surg. 2013 Oct; 79(10):1075-80. View in: PubMed

Effect of Barrett's esophagus surveillance on esophageal preservation, tumor stage, and survival with esophageal adenocarcinoma. J Thorac Cardiovasc Surg. 2013 Jul; 146(1):31-7. View in: PubMed

Adenocarcinoma of the esophagus in the young. J Gastrointest Surg. 2013 Jun; 17(6):1032-5. View in: PubMed

Invited commentary. Ann Thorac Surg. 2013 Feb; 95(2):463-4. View in: PubMed

Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression. Genome Res. 2012 Jul; 22(7):1197-211. View in: PubMed

Invited commentary. Ann Thorac Surg. 2012 Jun; 93(6):1854. View in: PubMed

Intraluminal pH and Goblet Cell Density in Barrett's Esophagus. J Gastrointest Surg. 2012 Mar; 16(3):469-74. View in: PubMed

Columnar-lined esophagus without intestinal metaplasia has no proven risk of adenocarcinoma. Am J Surg Pathol. 2012 Jan; 36(1):1-7. View in: PubMed

Invited commentary. Ann Thorac Surg. 2011 Dec; 92(6):2027. View in: PubMed

The dilated distal esophagus: a new entity that is the pathologic basis of early gastroesophageal reflux disease. Am J Surg Pathol. 2011 Dec; 35(12):1873-81. View in: PubMed

The gene expression profile of cardia intestinal metaplasia is similar to that of Barrett's esophagus, not gastric intestinal metaplasia. Dis Esophagus. 2011 Sep; 24(7):516-22. View in: PubMed

Circular stapled pyloroplasty: a fast and effective technique for pyloric disruption during esophagectomy with gastric pull-up. Dis Esophagus. 2011 Aug; 24(6):423-9. View in: PubMed

Day-to-day discrepancy in Bravo pH monitoring is related to the degree of deterioration of the lower esophageal sphincter and severity of reflux disease. Surg Endosc. 2011 Jul; 25(7):2219-23. View in: PubMed

Thoraco-abdominal pressure gradients during the phases of respiration contribute to gastroesophageal reflux disease. Dig Dis Sci. 2011 Jun; 56(6):1718-22. View in: PubMed

Laparoscopic versus open repair of paraesophageal hernia: the second decade. J Am Coll Surg. 2011 May; 212(5):813-20. View in: PubMed

The prevalence of lymph node metastases in patients with T1 esophageal adenocarcinoma a retrospective review of esophagectomy specimens. Ann Surg. 2011 Feb; 253(2):271-8. View in: PubMed

Endoscopic resection and ablation versus esophagectomy for high-grade dysplasia and intramucosal adenocarcinoma. J Thorac Cardiovasc Surg. 2011 Jan; 141(1):39-47. View in: PubMed

The histologic squamo-oxyntic gap: an accurate and reproducible diagnostic marker of gastroesophageal reflux disease. Am J Surg Pathol. 2010 Nov; 34(11):1574-81. View in: PubMed

Esophagectomy for cancer in octogenarians. Dis Esophagus. 2010 Nov; 23(8):666-9. View in: PubMed

Loss of alkalization in proximal esophagus: a new diagnostic paradigm for patients with laryngopharyngeal reflux. J Gastrointest Surg. 2010 Nov; 14(11):1653-9. View in: PubMed

Invited commentary. Ann Thorac Surg. 2010 Nov; 90(5):1667-8. View in: PubMed

Association of adenocarcinomas of the distal esophagus, "gastroesophageal junction," and "gastric cardia" with gastric pathology. Am J Surg Pathol. 2010 Oct; 34(10):1521-7. View in: PubMed

Long-term follow-up after anti-reflux surgery in patients with Barrett's esophagus. J Gastrointest Surg. 2010 Oct; 14(10):1483-91. View in: PubMed

Detection of gastric conduit ischemia or anastomotic breakdown after cervical esophagogastrostomy: the use of computed tomography scan versus early endoscopy. Surg Endosc. 2010 Aug; 24(8):1948-51. View in: PubMed

The impact of gastric distension on the lower esophageal sphincter and its exposure to acid gastric juice. Ann Surg. 2010 Jul; 252(1):57-62. View in: PubMed

Genetic variations in angiogenesis pathway genes predict tumor recurrence in localized adenocarcinoma of the esophagus. Ann Surg. 2010 May; 251(5):857-64. View in: PubMed

Progressive mucosal injury in patients with gastroesophageal reflux disease and increasing peripheral blood eosinophil counts. Arch Surg. 2010 Apr; 145(4):363-6. View in: PubMed

Recurrence after esophagectomy for adenocarcinoma: defining optimal follow-up intervals and testing. J Am Coll Surg. 2010 Apr; 210(4):428-35. View in: PubMed

Esophageal intraepithelial eosinophils in dysphagic patients with gastroesophageal reflux disease. Dig Dis Sci. 2010 Apr; 55(4):967-72. View in: PubMed

A simplified technique for intrathoracic stomach repair: laparoscopic fundoplication with Vicryl mesh and BioGlue crural reinforcement. Surg Endosc. 2010 Mar; 24(3):675-9. View in: PubMed

Proximal esophageal pH monitoring: improved definition of normal values and determination of a composite pH score. J Am Coll Surg. 2010 Mar; 210(3):345-50. View in: PubMed

Reliability of a procedural checklist as a high-stakes measurement of advanced technical skill. Am J Surg. 2010 Jan; 199(1):110-4. View in: PubMed

The value of high-resolution manometry in the assessment of the resting characteristics of the lower esophageal sphincter. J Gastrointest Surg. 2009 Dec; 13(12):2113-20. View in: PubMed

Clinical characteristics, biologic behavior, and survival after esophagectomy are similar for adenocarcinoma of the gastroesophageal junction and the distal esophagus. J Thorac Cardiovasc Surg. 2009 Sep; 138(3):594-602; discussion 601-2. View in: PubMed

Measurement of gastric pH in ambulatory esophageal pH monitoring. Surg Endosc. 2009 Sep; 23(9):1968-73. View in: PubMed

A new technique for measurement of pharyngeal pH: normal values and discriminating pH threshold. J Gastrointest Surg. 2009 Aug; 13(8):1422-9. View in: PubMed

Obesity and gastroesophageal reflux: quantifying the association between body mass index, esophageal acid exposure, and lower esophageal sphincter status in a large series of patients with reflux symptoms. J Gastrointest Surg. 2009 Aug; 13(8):1440-7. View in: PubMed

Giant cell tumor of the sternum. Ann Thorac Surg. 2009 Aug; 88(2):645-7. View in: PubMed

Validation of a rodent model of Barrett's esophagus using quantitative gene expression profiling. Surg Endosc. 2009 Jun; 23(6):1346-52. View in: PubMed

Delayed esophagogastrostomy: a safe strategy for management of patients with ischemic gastric conduit at time of esophagectomy. J Am Coll Surg. 2009 Jun; 208(6):1030-4. View in: PubMed

Laparoscopic Nissen fundoplication assessment: task analysis as a model for the development of a procedural checklist. Surg Endosc. 2009 Jun; 23(6):1227-32. View in: PubMed

Survival in lymph node negative adenocarcinoma of the esophagus after R0 resection with and without neoadjuvant therapy: evidence for downstaging of N status. J Am Coll Surg. 2009 Apr; 208(4):553-6. View in: PubMed

Hiatal hernia, lower esophageal sphincter incompetence, and effectiveness of Nissen fundoplication in the spectrum of gastroesophageal reflux disease. J Gastrointest Surg. 2009 Apr; 13(4):602-10. View in: PubMed

Esophageal pH exposure and epithelial cell differentiation. Dis Esophagus. 2009; 22(7):596-9. View in: PubMed

Recurrence of intramucosal esophageal adenocarcinoma arising in a former esophagostomy site: a unique case report. Dis Esophagus. 2009; 22(6):E17-20. View in: PubMed

An improved method of assessing esophageal emptying using the timed barium study following surgical myotomy for achalasia. J Gastrointest Surg. 2009 Jan; 13(1):14-8. View in: PubMed

Bravo catheter-free pH monitoring: normal values, concordance, optimal diagnostic thresholds, and accuracy. Clin Gastroenterol Hepatol. 2009 Jan; 7(1):60-7. View in: PubMed

Predicting systemic disease in patients with esophageal cancer after esophagectomy: a multinational study on the significance of the number of involved lymph nodes. Ann Surg. 2008 Dec; 248(6):979-85. View in: PubMed

The number of lymph nodes removed predicts survival in esophageal cancer: an international study on the impact of extent of surgical resection. Ann Surg. 2008 Oct; 248(4):549-56. View in: PubMed

Plasma DNA is more reliable than carcinoembryonic antigen for diagnosis of recurrent esophageal cancer. J Am Coll Surg. 2008 Jul; 207(1):30-5. View in: PubMed

En bloc esophagectomy reduces local recurrence and improves survival compared with transhiatal resection after neoadjuvant therapy for esophageal adenocarcinoma. J Thorac Cardiovasc Surg. 2008 Jun; 135(6):1228-36. View in: PubMed

Predictive value of preoperative plasma DNA level for early recurrence after resection in esophageal adenocarcinoma. J Clin Oncol. 2008 May 20; 26(15_suppl):4545. View in: PubMed

High intraepithelial eosinophil counts in esophageal squamous epithelium are not specific for eosinophilic esophagitis in adults. Am J Gastroenterol. 2008 Feb; 103(2):435-42. View in: PubMed

Plasma DNA: a molecular marker of surgical insult and postoperative recovery in esophageal cancer. Eur Surg Res. 2008; 40(3):273-8. View in: PubMed

Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer. Mol Cancer. 2008; 7:62. View in: PubMed

Vagal-sparing esophagectomy: the ideal operation for intramucosal adenocarcinoma and barrett with high-grade dysplasia. Ann Surg. 2007 Oct; 246(4):665-71; discussion 671-4. View in: PubMed

Plasma DNA as a molecular marker for completeness of resection and recurrent disease in patients with esophageal cancer. Arch Surg. 2007 Jun; 142(6):533-8; discussion 538-9. View in: PubMed

Reduction of interleukin 8 gene expression in reflux esophagitis and Barrett's esophagus with antireflux surgery. Arch Surg. 2007 Jun; 142(6):554-9; discussion 559-60. View in: PubMed

When are reflux episodes symptomatic? Dis Esophagus. When are reflux episodes symptomatic? Dis Esophagus. 2007; 20(1):47-52. View in: PubMed

Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma. Mol Cancer. 2007; 6:70. View in: PubMed

The role of DNA methylation in the development and progression of lung adenocarcinoma. Dis Markers. 2007; 23(1-2):5-30. View in: PubMed

Clinical and radiographic signs lead to early detection of lobar torsion and subsequent successful intervention. J Thorac Cardiovasc Surg. 2006 Sep; 132(3):720-1. View in: PubMed

Clinical biology and surgical therapy of intramucosal adenocarcinoma of the esophagus. J Am Coll Surg. 2006 Aug; 203(2):152-61. View in: PubMed

Antireflux surgery normalizes cyclooxygenase-2 expression in squamous epithelium of the distal esophagus. Am J Gastroenterol. 2006 Jul; 101(7):1458-66. View in: PubMed

The impact of reflux composition on mucosal injury and esophageal function. J Gastrointest Surg. 2006 Jun; 10(6):787-96; discussion 796-7. View in: PubMed

Response of the lower esophageal sphincter to gastric distention by carbonated beverages. J Gastrointest Surg. 2006 Jun; 10(6):870-7. View in: PubMed

Bravo capsule induction of esophageal hypercontractility and chest pain. Surg Endosc. 2006 May; 20(5):783-6. View in: PubMed

Molecular determinants in targeted therapy for esophageal adenocarcinoma. Arch Surg. 2006 May; 141(5):476-81; discussion 481-2. View in: PubMed

Gallstone-induced inflammatory fibrosis: a relentless clinical course of retained gallstones after laparoscopic cholecystectomy. Am Surg. 2006 Apr; 72(4):303-6. View in: PubMed

Modern 5-year survival of resectable esophageal adenocarcinoma: single institution experience with 263 patients. J Am Coll Surg. 2006 Apr; 202(4):588-96; discussion 596-8. View in: PubMed

Predictive factors of coexisting cancer in Barrett's high-grade dysplasia. Surg Endosc. 2006 Mar; 20(3):439-43. View in: PubMed

Can clinical and endoscopic findings accurately predict early-stage adenocarcinoma? Surg Endosc. Can clinical and endoscopic findings accurately predict early-stage adenocarcinoma? Surg Endosc. 2006 Feb; 20(2):294-7. View in: PubMed

Cdx-2 expression in squamous and metaplastic columnar epithelia of the esophagus. Dis Esophagus. 2006; 19(4):260-6. View in: PubMed

Survivin, a potential biomarker in the development of Barrett's adenocarcinoma. Surgery. 2005 Oct; 138(4):701-6; discussion 706-7. View in: PubMed

The safety and usefulness of endoscopy for evaluation of the graft and anastomosis early after esophagectomy and reconstruction. Surg Endosc. 2005 Aug; 19(8):1093-102. View in: PubMed

Comparison of the clinical and histological characteristics and survival of distal esophageal-gastroesophageal junction adenocarcinoma in patients with and without barrett mucosa. Arch Surg. 2005 Jun; 140(6):570-4; discussion 574-5. View in: PubMed

Barrett's esophagus in females: a comparative analysis of risk factors in females and males. Am J Gastroenterol. 2005 Mar; 100(3):560-7. View in: PubMed

Distinct DNA methylation profiles in malignant mesothelioma, lung adenocarcinoma, and non-tumor lung. Lung Cancer. 2005 Feb; 47(2):193-204. View in: PubMed

The mutagenic potential of duodenoesophageal reflux. Ann Surg. 2005 Jan; 241(1):63-8. View in: PubMed

Esophageal adenocarcinoma in patients < or = 50 years old: delayed diagnosis and advanced disease at presentation. Am Surg. 2004 Nov; 70(11):954-8. View in: PubMed

Omeprazole does not reduce gastroesophageal reflux: new insights using multichannel intraluminal impedance technology. J Gastrointest Surg. 2004 Nov; 8(7):890-7; discussion 897-8. View in: PubMed

The prognostic importance of immunohistochemically detected node metastases in resected esophageal adenocarcinoma. Ann Thorac Surg. 2004 Oct; 78(4):1161-9; discussion 1161-9. View in: PubMed

Increased acid exposure in patients with gastroesophageal reflux disease influences cyclooxygenase-2 gene expression in the squamous epithelium of the lower esophagus. Arch Surg. 2004 Jul; 139(7):712-6; discussion 716-7. View in: PubMed

En bloc vs transhiatal esophagectomy for stage T3 N1 adenocarcinoma of the distal esophagus. Arch Surg. 2004 Jun; 139(6):627-31; discussion 631-3. View in: PubMed

Prevalence and risk factors for ischemia, leak, and stricture of esophageal anastomosis: gastric pull-up versus colon interposition. J Am Coll Surg. 2004 Apr; 198(4):536-41; discussion 541-2. View in: PubMed

Preoperative lower esophageal sphincter pressure affects outcome of laparoscopic esophageal myotomy for achalasia. J Gastrointest Surg. 2004 Mar-Apr; 8(3):328-34. View in: PubMed

Chronology of the Barrett's metaplasia-dysplasia-carcinoma sequence. Dis Esophagus. 2004; 17(1):67-70. View in: PubMed

Barrett's esophagus. J Gastrointest Surg. 2004 Jan; 8(1):1-17. View in: PubMed

Surgical management of hypertensive lower esophageal sphincter with dysphagia or chest pain. J Gastrointest Surg. 2003 Dec; 7(8):990-6; discussion 996. View in: PubMed

Manometry of the lower esophageal sphincter: inter- and intraindividual variability of slow motorized pull-through versus station pull-through manometry. Dig Dis Sci. 2003 Jun; 48(6):1057-61. View in: PubMed

Barrett's esophagus can and does regress after antireflux surgery: a study of prevalence and predictive features. J Am Coll Surg. 2003 May; 196(5):706-12; discussion 712-3. View in: PubMed

Staging of esophageal carcinoma. J Thorac Cardiovasc Surg. 2003 May; 125(5):988-91. View in: PubMed

Etiology of intestinal metaplasia at the gastroesophageal junction. Surg Endosc. 2003 Jan; 17(1):43-8. View in: PubMed

Excellent quality of life after Nissen fundoplication depends on successful elimination of reflux symptoms and not the invasiveness of the surgical approach. Ann Thorac Surg. 2002 Oct; 74(4):1019-24; discussion 1024-5. View in: PubMed

Cytokeratin and DAS-1 immunostaining reveal similarities among cardiac mucosa, CIM, and Barrett's esophagus. Am J Gastroenterol. 2002 Oct; 97(10):2514-23. View in: PubMed

Vagal-sparing esophagectomy: a more physiologic alternative. Ann Surg. 2002 Sep; 236(3):324-35; discussion 335-6. View in: PubMed

DNA methylation analysis: a powerful new tool for lung cancer diagnosis. Oncogene. 2002 Aug 12; 21(35):5450-61. View in: PubMed

A safe and noninvasive test for vagal integrity revisited. Arch Surg. 2002 Aug; 137(8):954-8; discussion 958-9. View in: PubMed

Absence of gastroesophageal reflux disease in a majority of patients taking acid suppression medications after Nissen fundoplication. J Gastrointest Surg. 2002 Jan-Feb; 6(1):3-9; discussion 10. View in: PubMed

The crura and crura-sphincter pressure dynamics in patients with isolated upright and isolated supine reflux. Am Surg. 2001 Dec; 67(12):1150-6. View in: PubMed

Predictive factors of Barrett esophagus: multivariate analysis of 502 patients with gastroesophageal reflux disease. Arch Surg. 2001 Nov; 136(11):1267-73. View in: PubMed

Long-term outcome of antireflux surgery in patients with Barrett's esophagus. Ann Surg. 2001 Oct; 234(4):532-8; discussion 538-9. View in: PubMed

Esophageal adenocarcinoma. Ann Thorac Surg. 2001 Oct; 72(4):1430-2. View in: PubMed

Curative resection for esophageal adenocarcinoma: analysis of 100 en bloc esophagectomies. Ann Surg. 2001 Oct; 234(4):520-30; discussion 530-1. View in: PubMed

Risk factors and the prevalence of trocar site herniation after laparoscopic fundoplication. Surg Endosc. 2001 Jul; 15(7):663-6. View in: PubMed

Minimally invasive approaches to antireflux surgery. Semin Thorac Cardiovasc Surg. 2000 Jul; 12(3):157-72. View in: PubMed

Is adenocarcinoma following esophagoduodenostomy without carcinogen in the rat reflux-induced? J Surg Res. Is adenocarcinoma following esophagoduodenostomy without carcinogen in the rat reflux-induced? J Surg Res. 2000 Jun 15; 91(2):111-7. View in: PubMed

Determinants of intestinal metaplasia within the columnar-lined esophagus. Arch Surg. 2000 Jun; 135(6):651-5; discussion 655-6. View in: PubMed

Re: Editorial on outcomes of treatment for GERD. Am J Gastroenterol. 2000 May; 95(5):1362-4. View in: PubMed

Laparoscopic repair of large type III hiatal hernia: objective followup reveals high recurrence rate. J Am Coll Surg. 2000 May; 190(5):553-60; discussion 560-1. View in: PubMed

Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy. Pediatrics. 2000 Apr; 105(4):E51. View in: PubMed

Suppression of gastric acid secretion in patients with gastroesophageal reflux disease results in gastric bacterial overgrowth and deconjugation of bile acids. J Gastrointest Surg. 2000 Jan-Feb; 4(1):50-4. View in: PubMed

Abnormal esophageal body function: radiographic-manometric correlation. Am Surg. 1999 Oct; 65(10):911-4. View in: PubMed

Occult esophageal adenocarcinoma: extent of disease and implications for effective therapy. Ann Surg. 1999 Sep; 230(3):433-8; discussion 438-40. View in: PubMed

Helicobacter pylori is not associated with the manifestations of gastroesophageal reflux disease. Arch Surg. 1999 Jul; 134(7):722-6. View in: PubMed

Role of the lower esophageal sphincter and hiatal hernia in the pathogenesis of gastroesophageal reflux disease. J Gastrointest Surg. 1999 Jul-Aug; 3(4):405-10. View in: PubMed

Short esophagus: analysis of predictors and clinical implications. Arch Surg. 1999 Jun; 134(6):633-6; discussion 637-8. View in: PubMed

Multivariate analysis of factors predicting outcome after laparoscopic Nissen fundoplication. J Gastrointest Surg. 1999 May-Jun; 3(3):292-300. View in: PubMed

Node status in transmural esophageal adenocarcinoma and outcome after en bloc esophagectomy. J Thorac Cardiovasc Surg. 1999 May; 117(5):960-8. View in: PubMed

The extent of Barrett's esophagus depends on the status of the lower esophageal sphincter and the degree of esophageal acid exposure. J Thorac Cardiovasc Surg. 1999 Mar; 117(3):572-80. View in: PubMed

Prevalence and location of nodal metastases in distal esophageal adenocarcinoma confined to the wall: implications for therapy. J Thorac Cardiovasc Surg. 1999 Jan; 117(1):16-23; discussion 23-5. View in: PubMed

The impact of an antireflux procedure on intestinal metaplasia of the cardia. Ann Surg. 1998 Oct; 228(4):547-56. View in: PubMed

Pharyngeal swallowing disorders: selection for and outcome after myotomy. Ann Surg. 1998 Oct; 228(4):598-608. View in: PubMed

Recipient and donor outcomes in living related and unrelated lobar transplantation. Transplant Proc. 1998 Aug; 30(5):2261-3. View in: PubMed

The treatment of gastroesophageal reflux disease with laparoscopic Nissen fundoplication: prospective evaluation of 100 patients with "typical" symptoms. Ann Surg. 1998 Jul; 228(1):40-50. View in: PubMed

Esophageal replacement for end-stage benign esophageal disease. J Thorac Cardiovasc Surg. 1998 Jun; 115(6):1241-7; discussion 1247-9. View in: PubMed

Duodenoesophageal reflux induces esophageal adenocarcinoma without exogenous carcinogen. J Gastrointest Surg. 1998 May-Jun; 2(3):260-8. View in: PubMed

Treatment of advanced gastroesophageal reflux disease with Collis gastroplasty and Belsey partial fundoplication. Arch Surg. 1998 May; 133(5):523-8; discussion 528-9. View in: PubMed

Ultrasonic epithelial ablation of the lower esophagus without stricture formation. A new technique for Barrett's ablation. Surg Endosc. 1998 Apr; 12(4):342-6; discussion 346-7. View in: PubMed

Normal esophageal body function: a study using ambulatory esophageal manometry. Am J Gastroenterol. 1998 Feb; 93(2):183-7. View in: PubMed

Esophagectomy for unsuccessful antireflux operations. J Thorac Cardiovasc Surg. 1998 Feb; 115(2):296-300, 302; discussion 300-1. View in: PubMed

Experience with living-donor lobar transplantation for indications other than cystic fibrosis. J Thorac Cardiovasc Surg. 1997 Dec; 114(6):917-21; discussion 921-2. View in: PubMed

Inflammation and specialized intestinal metaplasia of cardiac mucosa is a manifestation of gastroesophageal reflux disease. Ann Surg. 1997 Oct; 226(4):522-30; discussion 530-2. View in: PubMed

Can the combination of symptoms and endoscopy confirm the presence of gastroesophageal reflux disease? Am Surg. Can the combination of symptoms and endoscopy confirm the presence of gastroesophageal reflux disease? Am Surg. 1997 Oct; 63(10):933-6. View in: PubMed

Isolated upright gastroesophageal reflux is not a contraindication for antireflux surgery. Surgery. 1997 Oct; 122(4):829-35. View in: PubMed

Nissen fundoplication prevents shortening of the sphincter during gastric distention. Arch Surg. 1997 Jul; 132(7):719-24; discussion 724-6. View in: PubMed

Management of Barrett's esophagus with dysplasia. Semin Thorac Cardiovasc Surg. 1997 Jul; 9(3):285-9. View in: PubMed

Recurrent acute otitis media: the significance of age at onset. Acta Otolaryngol. 1997 Jul; 117(4):578-84. View in: PubMed

Hair nicotine concentrations in mothers and children in relation to parental smoking. J Expo Anal Environ Epidemiol. 1997 Apr-Jun; 7(2):235-9. View in: PubMed

Duodenogastric reflux potentiates the injurious effects of gastroesophageal reflux. J Gastrointest Surg. 1997 Jan-Feb; 1(1):27-32; discussion 33. View in: PubMed

Early acute otitis media: determined by exposure to respiratory pathogens. Acta Otolaryngol Suppl. 1997; 529:14-8. View in: PubMed

Breastfeeding, maternal smoking and lower respiratory tract infections. Eur Respir J. 1996 Dec; 9(12):2623-9. View in: PubMed

Living-donor lobar lung transplantation experience: intermediate results. J Thorac Cardiovasc Surg. 1996 Nov; 112(5):1284-90; discussion 1290-1. View in: PubMed

Talc pleurodesis: talc slurry versus thoracoscopic talc insufflation in a porcine model. Ann Thorac Surg. 1996 Oct; 62(4):1000-2; discussion 1003-4. View in: PubMed

Bilateral lobar transplantation utilizing living related donors. Artif Organs. 1996 Oct; 20(10):1110-1. View in: PubMed

Outcome of respiratory symptoms after antireflux surgery on patients with gastroesophageal reflux disease. Arch Surg. 1996 May; 131(5):489-92. View in: PubMed

The role of fundoplication in the treatment of type II paraesophageal hernia. J Thorac Cardiovasc Surg. 1996 Mar; 111(3):655-61. View in: PubMed

Carcinoembryonic antigen measurements in the management of esophageal cancer: an indicator of subclinical recurrence. Am J Surg. 1995 Dec; 170(6):597-600; discussion 600-1. View in: PubMed

Mixed reflux of gastric and duodenal juices is more harmful to the esophagus than gastric juice alone. The need for surgical therapy re-emphasized. Ann Surg. 1995 Oct; 222(4):525-31; discussion 531-3. View in: PubMed

Nodal metastasis and sites of recurrence after en bloc esophagectomy for adenocarcinoma. Ann Thorac Surg. 1994 Sep; 58(3):646-53; discussion 653-4. View in: PubMed

The effect of symptoms and nonspecific motility abnormalities on outcomes of surgical therapy for gastroesophageal reflux disease. J Thorac Cardiovasc Surg. 1994 May; 107(5):1244-9; discussion 1249-50. View in: PubMed

Superiority of extended en bloc esophagogastrectomy for carcinoma of the lower esophagus and cardia. J Thorac Cardiovasc Surg. 1993 Nov; 106(5):850-8; discussion 858-9. View in: PubMed

Surgery and the management of peripheral lung tumors adherent to the parietal pleura. J Thorac Cardiovasc Surg. 1992 Jan; 103(1):8-12; discussion 12-3. View in: PubMed

Alteration by burn injury of the pharmacokinetics and pharmacodynamics of cimetidine in children. Eur J Clin Pharmacol. 1989; 36(4):361-7. View in: PubMed

Vertical banded gastroplasty as an antireflux procedure. Am J Surg. 1988 Mar; 155(3):512-6. View in: PubMed

Gastroesophageal reflux in the massively obese. Int Surg. 1987 Jan-Mar; 72(1):1-3. View in: PubMed

The cardiovascular action of oxygen breathing: effect on adrenergic stimulation. Eur Surg Res. 1983; 15(4):185-92. View in: PubMed

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