Faculty

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Jobin Varkey, PhD
Assistant Professor of Research Biochemistry & Molecular Medicine
Zilkha Neurogenetic Institute
ZNI 115 Health Sciences Campus Los Angeles
+1 323 442 0106

Awards

Department of Biotechnology, Government of India: DBT Ramalingaswami Fellowship, 2013-2016

Council of Scientific and Industrial Research, Government of India: Senior Research Fellowship, 2004-2007

Department of Biotechnology, Government of India: MS Scholarship, 1999-2001

Council of Scientific and Industrial Research, Government of India: Junior Research Fellowship, 2002-2004

Department of Biotechnology, Government of India: award conferred by, 2013-2016

Council of Scientific and Industrial Research, Government of India: award conferred by, 2002-2004

Department of Biotechnology, Government of India: award conferred by, 1999-2001

Council of Scientific and Industrial Research, Government of India: award conferred by, 2004-2007

Department of Biotechnology, Government of India: Department, 1999-2001

Council of Scientific and Industrial Research, Government of India: Department, 2004-2007

Department of Biotechnology, Government of India: Department, 2013-2016

Council of Scientific and Industrial Research, Government of India: Department, 2002-2004

Council of Scientific and Industrial Research, Government of India: award or honor for, 2004-2007

Department of Biotechnology, Government of India: award or honor for, 2013-2016

Council of Scientific and Industrial Research, Government of India: award or honor for, 2002-2004

Department of Biotechnology, Government of India: award or honor for, 1999-2001

Department of Biotechnology, Government of India: full name, 1999-2001

Council of Scientific and Industrial Research, Government of India: full name, 2002-2004

Department of Biotechnology, Government of India: full name, 2013-2016

Council of Scientific and Industrial Research, Government of India: full name, 2004-2007

Council of Scientific and Industrial Research, Government of India: person in primary position, 2004-2007

Department of Biotechnology, Government of India: person in primary position, 1999-2001

Council of Scientific and Industrial Research, Government of India: person in primary position, 2002-2004

Department of Biotechnology, Government of India: person in primary position, 2013-2016

Council of Scientific and Industrial Research, Government of India: last name, 2004-2007

Council of Scientific and Industrial Research, Government of India: last name, 2002-2004

Department of Biotechnology, Government of India: last name, 1999-2001

Department of Biotechnology, Government of India: last name, 2013-2016

Department of Biotechnology, Government of India: HR job title, 2013-2016

Council of Scientific and Industrial Research, Government of India: HR job title, 2002-2004

Council of Scientific and Industrial Research, Government of India: HR job title, 2004-2007

Department of Biotechnology, Government of India: HR job title, 1999-2001

Council of Scientific and Industrial Research, Government of India: position in department, 2002-2004

Department of Biotechnology, Government of India: position in department, 1999-2001

Department of Biotechnology, Government of India: position in department, 2013-2016

Council of Scientific and Industrial Research, Government of India: position in department, 2004-2007

Department of Biotechnology, Government of India: sort order, 2013-2016

Council of Scientific and Industrial Research, Government of India: sort order, 2004-2007

Council of Scientific and Industrial Research, Government of India: sort order, 2002-2004

Department of Biotechnology, Government of India: sort order, 1999-2001

Council of Scientific and Industrial Research, Government of India: Assistant Professor, 2004-2007

Council of Scientific and Industrial Research, Government of India: Assistant Professor, 2002-2004

Department of Biotechnology, Government of India: Assistant Professor, 2013-2016

Department of Biotechnology, Government of India: Assistant Professor, 1999-2001

Department of Biotechnology, Government of India: email address, 2013-2016

Council of Scientific and Industrial Research, Government of India: email address, 2002-2004

Department of Biotechnology, Government of India: email address, 1999-2001

Council of Scientific and Industrial Research, Government of India: email address, 2004-2007

Council of Scientific and Industrial Research, Government of India: start date, 2002-2004

Council of Scientific and Industrial Research, Government of India: start date, 2004-2007

Department of Biotechnology, Government of India: start date, 1999-2001

Department of Biotechnology, Government of India: start date, 2013-2016

Department of Biotechnology, Government of India: type, 1999-2001

Department of Biotechnology, Government of India: type, 2013-2016

Council of Scientific and Industrial Research, Government of India: type, 2004-2007

Council of Scientific and Industrial Research, Government of India: type, 2002-2004

Department of Biotechnology, Government of India: end date, 2013-2016

Council of Scientific and Industrial Research, Government of India: end date, 2002-2004

Department of Biotechnology, Government of India: end date, 1999-2001

Council of Scientific and Industrial Research, Government of India: end date, 2004-2007

Department of Biotechnology, Government of India: workplace homepage, 1999-2001

Department of Biotechnology, Government of India: workplace homepage, 2013-2016

Council of Scientific and Industrial Research, Government of India: workplace homepage, 2002-2004

Council of Scientific and Industrial Research, Government of India: label, 2002-2004

Department of Biotechnology, Government of India: label, 1999-2001

Council of Scientific and Industrial Research, Government of India: label, 2004-2007

Department of Biotechnology, Government of India: label, 2013-2016

Council of Scientific and Industrial Research, Government of India: Faculty Rank, 2004-2007

Council of Scientific and Industrial Research, Government of India: Faculty Rank, 2002-2004

Department of Biotechnology, Government of India: Faculty Rank, 2013-2016

Department of Biotechnology, Government of India: Faculty Rank, 1999-2001

Council of Scientific and Industrial Research, Government of India: is primary position, 2004-2007

Department of Biotechnology, Government of India: is primary position, 1999-2001

Department of Biotechnology, Government of India: is primary position, 2013-2016

Council of Scientific and Industrial Research, Government of India: is primary position, 2002-2004

Council of Scientific and Industrial Research, Government of India: preferred title, 2004-2007

Council of Scientific and Industrial Research, Government of India: preferred title, 2002-2004

Department of Biotechnology, Government of India: preferred title, 2013-2016

Department of Biotechnology, Government of India: preferred title, 1999-2001

Department of Biotechnology, Government of India: Zilkha Neurogenetic Institute, 2013-2016

Council of Scientific and Industrial Research, Government of India: Zilkha Neurogenetic Institute, 2004-2007

Council of Scientific and Industrial Research, Government of India: Zilkha Neurogenetic Institute, 2002-2004

Department of Biotechnology, Government of India: Zilkha Neurogenetic Institute, 1999-2001

Council of Scientific and Industrial Research, Government of India: first name, 2002-2004

Department of Biotechnology, Government of India: first name, 2013-2016

Department of Biotechnology, Government of India: first name, 1999-2001

Council of Scientific and Industrial Research, Government of India: first name, 2004-2007

Department of Biotechnology, Government of India: position in organization, 1999-2001

Council of Scientific and Industrial Research, Government of India: position in organization, 2004-2007

Council of Scientific and Industrial Research, Government of India: position in organization, 2002-2004

Department of Biotechnology, Government of India: position in organization, 2013-2016

Department of Biotechnology, Government of India: Assistant Professor of Research Biochemistry & Molecular Medicine, 2013-2016

Council of Scientific and Industrial Research, Government of India: Assistant Professor of Research Biochemistry & Molecular Medicine, 2002-2004

Council of Scientific and Industrial Research, Government of India: Assistant Professor of Research Biochemistry & Molecular Medicine, 2004-2007

Department of Biotechnology, Government of India: Person ID, 1999-2001

Council of Scientific and Industrial Research, Government of India: Person ID, 2004-2007

Council of Scientific and Industrial Research, Government of India: Person ID, 2002-2004

Department of Biotechnology, Government of India: Person ID, 2013-2016

Council of Scientific and Industrial Research, Government of India: Organization, 2002-2004

Council of Scientific and Industrial Research, Government of India: Organization, 2004-2007

Department of Biotechnology, Government of India: Organization, 2013-2016

Department of Biotechnology, Government of India: Organization, 1999-2001

Department of Biotechnology, Government of India: Varkey, Jobin, 1999-2001

Department of Biotechnology, Government of India: Varkey, Jobin, 2013-2016

Council of Scientific and Industrial Research, Government of India: Varkey, Jobin, 2002-2004

Council of Scientific and Industrial Research, Government of India: Keck School of Medicine of USC, 2004-2007

Council of Scientific and Industrial Research, Government of India: Keck School of Medicine of USC, 2002-2004

Department of Biotechnology, Government of India: Keck School of Medicine of USC, 1999-2001

Council of Scientific and Industrial Research, Government of India: Varkey, Jobin, 2004-2007

Department of Biotechnology, Government of India: Position, 2013-2016

Department of Biotechnology, Government of India: Position, 1999-2001

Council of Scientific and Industrial Research, Government of India: Position, 2002-2004

Council of Scientific and Industrial Research, Government of India: Position, 2004-2007

Council of Scientific and Industrial Research, Government of India: has faculty rank, 2002-2004

Department of Biotechnology, Government of India: has faculty rank, 1999-2001

Department of Biotechnology, Government of India: has faculty rank, 2013-2016

Council of Scientific and Industrial Research, Government of India: has faculty rank, 2004-2007

Publications

. View in: PubMed

a-Synuclein Amyloid Fibrils with Two Entwined, Asymmetrically Associated Protofibrils. J Biol Chem. 2016 Jan 29; 291(5):2310-8. View in: PubMed

Basak S, Prasad GV, Varkey J, Chattopadhyay K. Early sodium dodecyl sulfate induced collapse of a-synuclein correlates with its amyloid formation. ACS Chem Neurosci. 2015 Feb 18; 6(2):239-46. View in: PubMed

Basak S, Prasad GV, Varkey J, Chattopadhyay K. Early sodium dodecyl sulfate induced collapse of a-synuclein correlates with its amyloid formation. ACS Chem Neurosci. 2015 Feb 18; 6(2):239-46. View in: PubMed

Lai Y, Kim S, Varkey J, Lou X, Song JK, Diao J, Langen R, Shin YK. Nonaggregated a-Synuclein Influences SNARE-Dependent Vesicle Docking via Membrane Binding. Biochemistry. 2014 Jun 24; 53(24):3889-96. View in: PubMed

Lai Y, Kim S, Varkey J, Lou X, Song JK, Diao J, Langen R, Shin YK. Nonaggregated a-Synuclein Influences SNARE-Dependent Vesicle Docking via Membrane Binding. Biochemistry. 2014 Jun 24; 53(24):3889-96. View in: PubMed

Cheng CY, Varkey J, Ambroso MR, Langen R, Han S. Hydration dynamics as an intrinsic ruler for refining protein structure at lipid membrane interfaces. Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42):16838-43. View in: PubMed

Cheng CY, Varkey J, Ambroso MR, Langen R, Han S. Hydration dynamics as an intrinsic ruler for refining protein structure at lipid membrane interfaces. Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42):16838-43. View in: PubMed

Varkey J, Mizuno N, Hegde BG, Cheng N, Steven AC, Langen R. a-Synuclein oligomers with broken helical conformation form lipoprotein nanoparticles. J Biol Chem. 2013 Jun 14; 288(24):17620-30. View in: PubMed

Varkey J, Mizuno N, Hegde BG, Cheng N, Steven AC, Langen R. a-Synuclein oligomers with broken helical conformation form lipoprotein nanoparticles. J Biol Chem. 2013 Jun 14; 288(24):17620-30. View in: PubMed

Ladiwala AR, Bhattacharya M, Perchiacca JM, Cao P, Raleigh DP, Abedini A, Schmidt AM, Varkey J, Langen R, Tessier PM. Rational design of potent domain antibody inhibitors of amyloid fibril assembly. Proc Natl Acad Sci U S A. 2012 Dec 4; 109(49):19965-70. View in: PubMed

Ladiwala AR, Bhattacharya M, Perchiacca JM, Cao P, Raleigh DP, Abedini A, Schmidt AM, Varkey J, Langen R, Tessier PM. Rational design of potent domain antibody inhibitors of amyloid fibril assembly. Proc Natl Acad Sci U S A. 2012 Dec 4; 109(49):19965-70. View in: PubMed

Mizuno N, Varkey J, Kegulian NC, Hegde BG, Cheng N, Langen R, Steven AC. Remodeling of Lipid Vesicles into Cylindrical Micelles by a-Synuclein in an Extended a-Helical Conformation. J Biol Chem. 2012 Aug 24; 287(35):29301-11. View in: PubMed

Mizuno N, Varkey J, Kegulian NC, Hegde BG, Cheng N, Langen R, Steven AC. Remodeling of Lipid Vesicles into Cylindrical Micelles by a-Synuclein in an Extended a-Helical Conformation. J Biol Chem. 2012 Aug 24; 287(35):29301-11. View in: PubMed

Semisynthetic, Site-Specific Ubiquitin Modification of a-Synuclein Reveals Differential Effects on Aggregation. J Am Chem Soc. 2012 Mar 28; 134(12):5468-71. View in: PubMed

Membrane curvature induction and tubulation are common features of synucleins and apolipoproteins. J Biol Chem. 2010 Oct 15; 285(42):32486-93. View in: PubMed

Antibacterial activity of linear peptides spanning the carboxy-terminal beta-sheet domain of arthropod defensins. Peptides. 2006 Nov; 27(11):2614-23. View in: PubMed

Antibacterial activity of human neutrophil defensin HNP-1 analogs without cysteines. Antimicrob Agents Chemother. 2005 Nov; 49(11):4561-6. View in: PubMed

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