Faculty

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Joseph T. Rodgers, PhD
Assistant Professor of Stem Cell & Regenerative Medicine
Stem Cell Biology & Regenerative Medicine
Broad CIRM Center (BCC) Health Sciences Campus Los Angeles
+1 323 865 1549

Publications

HGFA Is an Injury-Regulated Systemic Factor that Induces the Transition of Stem Cells into GAlert. Cell Rep. 2017 Apr 18; 19(3):479-486. View in: PubMed

Deteriorating Infrastructure in the Aged Muscle Stem Cell Niche. Cell Stem Cell. 2016 08 04; 19(2):150-1. View in: PubMed

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert). Nature. 2014 Jun 19; 510(7505):393-6. View in: PubMed

USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy. Mol Endocrinol. 2014 Jun; 28(6):912-24. View in: PubMed

Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1a and MED1 complex. Diabetes. 2014 May; 63(5):1519-32. View in: PubMed

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 2014 Apr 10; 508(7495):258-62. View in: PubMed

Sprouting a new take on stem cell aging. EMBO J. 2012 Nov 5; 31(21):4103-5. View in: PubMed

Sprouting a new take on stem cell aging. EMBO J. 2012 Nov 05; 31(21):4103-5. View in: PubMed

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev. 2010 Jul 1; 24(13):1403-17. View in: PubMed

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. Genes Dev. 2010 Jul 01; 24(13):1403-17. View in: PubMed

Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis. Cell Metab. 2010 Jan; 11(1):23-34. View in: PubMed

Foxo1 integrates insulin signaling with mitochondrial function in the liver. Nat Med. 2009 Nov; 15(11):1307-11. View in: PubMed

Insulin resistance: beta-arrestin development. Cell Res. 2009 Mar; 19(3):275-6. View in: PubMed

A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose. J Biol Chem. 2009 Feb 20; 284(8):5148-57. View in: PubMed

O-GlcNAc regulates FoxO activation in response to glucose. J Biol Chem. 2008 Jun 13; 283(24):16283-92. View in: PubMed

Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways. FEBS Lett. 2008 Jan 09; 582(1):46-53. View in: PubMed

Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways. FEBS Lett. 2008 Jan 9; 582(1):46-53. View in: PubMed

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. Nature. 2007 Nov 29; 450(7170):736-40. View in: PubMed

Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1. Proc Natl Acad Sci U S A. 2007 Jul 31; 104(31):12861-6. View in: PubMed

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J. 2007 Jul 11; 26(13):3169-79. View in: PubMed

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. EMBO J. 2007 Apr 04; 26(7):1913-23. View in: PubMed

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. EMBO J. 2007 Apr 4; 26(7):1913-23. View in: PubMed

Receptor feasts on sugar and cholesterol. Nat Med. 2007 Feb; 13(2):128-9. View in: PubMed

Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1alpha. Proc Natl Acad Sci U S A. 2006 Oct 17; 103(42):15410-5. View in: PubMed

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J Biol Chem. 2006 Aug 4; 281(31):21745-54. View in: PubMed

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J Biol Chem. 2006 Aug 04; 281(31):21745-54. View in: PubMed

GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha. Cell Metab. 2006 Jun; 3(6):429-38. View in: PubMed

Certainly can't live without this: SIRT6. Cell Metab. 2006 Feb; 3(2):77-8. View in: PubMed

Foxa2, a novel transcriptional regulator of insulin sensitivity. Nat Med. 2006 Jan; 12(1):38-9. View in: PubMed

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature. 2005 Mar 3; 434(7029):113-8. View in: PubMed

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature. 2005 Mar 03; 434(7029):113-8. View in: PubMed

Discrimination among individual Watson-Crick base pairs at the termini of single DNA hairpin molecules. Nucleic Acids Res. 2003 Feb 15; 31(4):1311-8. View in: PubMed

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