Faculty

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Joyce M. Richey, PhD
Assistant Professor of Research Physiology & Biophysics
Assistant Dean For Student Affairs
Chief Diversity officer
Physiology and Biophysics
CSC 213 2250 Alcazar Street Health Sciences Campus Los Angeles
+1 323 442 1939

Overview

Dr. Richey is currently a faculty member in the department of Physiology and Biophysics at Keck School of Medicine of USC and a member of the diabetes and obesity research groups. Dr. Richey conducts research examining the relationship between diabetes, obesity and hypertension.

She has received research grants from the National Institute of Digestive, Diabetes and Kidney Disorders; National Institute of Heart, Lung and Blood; American Heart Association and the American Diabetes Association. Her research has resulted in publications in peer-reviewed medical journals. She is the immediate past president of the Los Leadership Council of the American Diabetes Association; chairperson of the Los Angeles African American Diabetes Task Force; and a peer grant reviewer for the Western and National Affiliates of the American Heart Association.

Publications

Kabir M, Iyer MS, Richey JM, Woolcott OO, Asare Bediako I, Wu Q, Kim SP, Stefanovski D, Kolka CM, Hsu IR, Catalano KJ, Chiu JD, Ionut V, Bergman RN. CB1R antagonist increases hepatic insulin clearance in fat-fed dogs likely via upregulation of liver adiponectin receptors. Am J Physiol Endocrinol Metab. 2015 Oct 15; 309(8):E747-58. View in: PubMed

Kolka CM, Richey JM, Castro AV, Broussard JL, Ionut V, Bergman RN. Lipid-induced insulin resistance does not impair insulin access to skeletal muscle. Am J Physiol Endocrinol Metab. 2015 Jun 1; 308(11):E1001-9. View in: PubMed

Alderete TL, Sattler FR, Richey JM, Allayee H, Mittelman SD, Sheng X, Tucci J, Gyllenhammer LE, Grant EG, Goran MI. Salsalate treatment improves glycemia without altering adipose tissue in nondiabetic obese hispanics. Obesity (Silver Spring). 2015 Feb 3. View in: PubMed

Woolcott OO, Richey JM, Kabir M, Chow RH, Iyer MS, Kirkman EL, Stefanovski D, Lottati M, Kim SP, Harrison LN, Ionut V, Zheng D, Hsu IR, Catalano KJ, Chiu JD, Bradshaw H, Wu Q, Kolka CM, Bergman RN. Corrections: High-Fat Diet-Induced Insulin Resistance does not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets. PLoS One. 2015; 10(6):e0131033. View in: PubMed

Woolcott OO, Richey JM, Kabir M, Chow RH, Iyer MS, Kirkman EL, Stefanovski D, Lottati M, Kim SP, Harrison LN, Ionut V, Zheng D, Hsu IR, Catalano KJ, Chiu JD, Bradshaw H, Wu Q, Bergman RN. High-fat diet-induced insulin resistance does not increase plasma anandamide levels or potentiate anandamide insulinotropic effect in isolated canine islets. PLoS One. 2015; 10(4):e0123558. View in: PubMed

Toledo-Corral CM, Alderete TL, Richey J, Sequeira P, Goran MI, Weigensberg MJ. Fasting, post-OGTT challenge, and nocturnal free fatty acids in prediabetic versus normal glucose tolerant overweight and obese Latino adolescents. Acta Diabetol. 2014 Aug 11. View in: PubMed

Ren J, Xiang AH, Trigo E, Takayanagi M, Beale E, Lawrence JM, Hartiala J, Richey JM, Allayee H, Buchanan TA, Watanabe RM. Genetic variation in MTNR1B is associated with gestational diabetes mellitus and contributes only to the absolute level of beta cell compensation in Mexican Americans. Diabetologia. 2014 Jul; 57(7):1391-9. View in: PubMed

Ader M, Stefanovski D, Richey JM, Kim SP, Kolka CM, Ionut V, Kabir M, Bergman RN. Failure of homeostatic model assessment of insulin resistance to detect marked diet-induced insulin resistance in dogs. Diabetes. 2014 Jun; 63(6):1914-9. View in: PubMed

Ader M, Stefanovski D, Kim SP, Richey JM, Ionut V, Catalano KJ, Hucking K, Ellmerer M, Van Citters G, Hsu IR, Chiu JD, Woolcott OO, Harrison LN, Zheng D, Lottati M, Kolka CM, Mooradian V, Dittmann J, Yae S, Liu H, Castro AV, Kabir M, Bergman RN. Hepatic insulin clearance is the primary determinant of insulin sensitivity in the normal dog. Obesity (Silver Spring). 2014 May; 22(5):1238-45. View in: PubMed

Richey JM. The Vascular Endothelium, a Benign Restrictive Barrier? NO! Role of Nitric Oxide in Regulating Insulin Action. Diabetes. 2013 Dec; 62(12):4006-8. View in: PubMed

Kim SP, Woolcott OO, Hsu IR, Stefanoski D, Harrison LN, Zheng D, Lottati M, Kolka C, Catalano KJ, Chiu JD, Kabir M, Ionut V, Bergman RN, Richey JM. CB1 antagonism restores hepatic insulin sensitivity without normalization of adiposity in diet-induced obese dogs. Am J Physiol Endocrinol Metab. 2012 May; 302(10):E1261-8. View in: PubMed

Spruijt-Metz D, Adar Emken B, Spruijt MR, Richey JM, Berman LJ, Belcher BR, Hsu YW, McClain AD, Lane CJ, Weigensberg MJ. CRP Is Related to Higher Leptin Levels in Minority Peripubertal Females Regardless of Adiposity Levels. Obesity (Silver Spring). 2012 Mar; 20(3):512-6. View in: PubMed

Woolcott OO, Bergman RN, Richey JM, Kirkman EL, Harrison LN, Ionut V, Lottati M, Zheng D, Hsu IR, Stefanovski D, Kabir M, Kim SP, Catalano KJ, Chiu JD, Chow RH. Simplified method to isolate highly pure canine pancreatic islets. Pancreas. 2012 Jan; 41(1):31-8. View in: PubMed

Kabir M, Stefanovski D, Hsu IR, Iyer M, Woolcott OO, Zheng D, Catalano KJ, Chiu JD, Kim SP, Harrison LN, Ionut V, Lottati M, Bergman RN, Richey JM. Large size cells in the visceral adipose depot predict insulin resistance in the canine model. Obesity (Silver Spring). 2011 Nov; 19(11):2121-9. View in: PubMed

Stefanovski D, Richey JM, Woolcott O, Lottati M, Zheng D, Harrison LN, Ionut V, Kim SP, Hsu I, Bergman RN. Consistency of the disposition index in the face of diet induced insulin resistance: potential role of FFA. PLoS One. 2011; 6(3):e18134. View in: PubMed

Emken BA, Richey J, Belcher B, Hsu YW, Spruijt-Metz D. Objectively measured physical activity is negatively associated with plasma adiponectin levels in minority female youth. Int J Pediatr Endocrinol. 2010; 2010. View in: PubMed

Chiu JD, Kolka CM, Richey JM, Harrison LN, Zuniga E, Kirkman EL, Bergman RN. Experimental hyperlipidemia dramatically reduces access of insulin to canine skeletal muscle. Obesity (Silver Spring). 2009 Aug; 17(8):1486-92. View in: PubMed

Spruijt-Metz D, Belcher B, Anderson D, Lane CJ, Chou CP, Salter-Venzon D, Davis JN, Hsu YW, Neuhouser ML, Richey JM, McKenzie TL, McClain A, Goran MI, Weigensberg MJ. A high-sugar/low-fiber meal compared with a low-sugar/high-fiber meal leads to higher leptin and physical activity levels in overweight Latina females. J Am Diet Assoc. 2009 Jun; 109(6):1058-63. View in: PubMed

Richey JM, Woolcott OO, Stefanovski D, Harrison LN, Zheng D, Lottati M, Hsu IR, Kim SP, Kabir M, Catalano KJ, Chiu JD, Ionut V, Kolka C, Mooradian V, Bergman RN. Rimonabant prevents additional accumulation of visceral and subcutaneous fat during high-fat feeding in dogs. Am J Physiol Endocrinol Metab. 2009 Jun; 296(6):E1311-8. View in: PubMed

Chiu JD, Richey JM, Harrison LN, Zuniga E, Kolka CM, Kirkman E, Ellmerer M, Bergman RN. Direct administration of insulin into skeletal muscle reveals that the transport of insulin across the capillary endothelium limits the time course of insulin to activate glucose disposal. Diabetes. 2008 Apr; 57(4):828-35. View in: PubMed

Kim SP, Catalano KJ, Hsu IR, Chiu JD, Richey JM, Bergman RN. Nocturnal free fatty acids are uniquely elevated in the longitudinal development of diet-induced insulin resistance and hyperinsulinemia. Am J Physiol Endocrinol Metab. 2007 Jun; 292(6):E1590-8. View in: PubMed

Bergman RN, Kim SP, Hsu IR, Catalano KJ, Chiu JD, Kabir M, Richey JM, Ader M. Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk. Am J Med. 2007 Feb; 120(2 Suppl 1):S3-8; discussion S29-32. View in: PubMed

Ellmerer M, Hamilton-Wessler M, Kim SP, Huecking K, Kirkman E, Chiu J, Richey J, Bergman RN. Reduced access to insulin-sensitive tissues in dogs with obesity secondary to increased fat intake. Diabetes. 2006 Jun; 55(6):1769-75. View in: PubMed

Ader M, Kim SP, Catalano KJ, Ionut V, Hucking K, Richey JM, Kabir M, Bergman RN. Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: a placebo-controlled study of olanzapine and risperidone in dogs. Diabetes. 2005 Mar; 54(3):862-71. View in: PubMed

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