Faculty

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Julie E. Lang, MD
Associate Professor of Clinical Surgery
Director, Breast Cancer Program, Department of Surgery
Surgery
HCC 514 Health Sciences Campus Los Angeles
+1 323 442 6229

Overview

Julie Lang, MD, FACS is an Associate Professor at the Keck School of Medicine of USC. She earned her medical degree from the University of North Carolina, Chapel Hill. She then went on to complete a Surgery residency and a postdoctoral research fellowship in breast cancer research at the University of California, San Francisco. She completed her breast surgical oncology fellowship at the UT-MD Anderson Cancer Center in 2007. She served as the Director of Breast Surgical Oncology at the Arizona Cancer Center for 5 years, then joined the faculty of USC in 2012. Dr. Lang is an expert in the field of breast surgical oncology, with strong expertise in both clinical care and research in the field of breast cancer. She is experienced with advanced breast surgical techniques, such as skin sparing, nipple sparing mastectomies, and coordinating reconstructive surgery with colleagues in Plastic Surgery. Her research focuses on circulating tumor cells, clinical trials, locally advanced/inflammatory breast cancer and radiation-induced sarcoma. Dr. Lang is an avid breast cancer researcher and leads the Breast Surgical Oncology Translational Research Laboratory at the Norris Comprehensive Cancer Center. Dr. Lang is very patient centered and strives to utilize technology and evidenced based medicine to the benefit of her patients. She has published numerous peer reviewed articles and book chapters on the topic of breast cancer.

Publications

Matriptase regulates c-Met mediated proliferation and invasion in inflammatory breast cancer. Oncotarget. 2016 Sep 06; 7(36):58162-58173. View in: PubMed

Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer. N Engl J Med. 2016 Jul 7; 375(1):23-34. View in: PubMed

Adaptive Randomization of Neratinib in Early Breast Cancer. N Engl J Med. 2016 Jul 7; 375(1):11-22. View in: PubMed

The importance of surgical margins in breast cancer. J Surg Oncol. 2016 Mar; 113(3):256-63. View in: PubMed

The potential for liquid biopsies in the precision medical treatment of breast cancer. Cancer Biol Med. 2016 Mar; 13(1):19-40. View in: PubMed

Double-Blind, Randomized Trial of Alternative Letrozole Dosing Regimens in Postmenopausal Women with Increased Breast Cancer Risk. Cancer Prev Res (Phila). 2016 Feb; 9(2):142-8. View in: PubMed

EpCAM based capture detects and recovers circulating tumor cells from all subtypes of breast cancer except claudin-low. Oncotarget. 2015 Dec 29; 6(42):44623-34. View in: PubMed

Oxidative stress, mammospheres and Nrf2-new implication for breast cancer therapy? Mol Carcinog. Oxidative stress, mammospheres and Nrf2-new implication for breast cancer therapy? Mol Carcinog. 2015 Nov; 54(11):1494-502. View in: PubMed

High-frequency ultrasound imaging for breast cancer biopsy guidance. J Med Imaging (Bellingham). 2015 Oct; 2(4):047001. View in: PubMed

Lymph node status in inflammatory breast cancer. Breast Cancer Res Treat. 2015 May; 151(1):113-20. View in: PubMed

Malignancy rates after surgical excision of discordant breast biopsies. J Surg Res. 2015 May 1; 195(1):152-7. View in: PubMed

Characterization of a novel radiation-induced sarcoma cell line. J Surg Oncol. 2015 May; 111(6):669-82. View in: PubMed

Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling. Nat Commun. 2015; 6:6776. View in: PubMed

Expression profiling of circulating tumor cells in metastatic breast cancer. Breast Cancer Res Treat. 2015 Jan; 149(1):121-31. View in: PubMed

Plasma metabolomic profiles of breast cancer patients after short-term limonene intervention. Cancer Prev Res (Phila). 2015 Jan; 8(1):86-93. View in: PubMed

Molecular markers for breast cancer diagnosis, prognosis and targeted therapy. J Surg Oncol. 2015 Jan; 111(1):81-90. View in: PubMed

Breast reconstruction satisfaction rates at a large county hospital. Ann Plast Surg. 2014 May; 72 Suppl 1:S61-5. View in: PubMed

Trends in post-mastectomy reconstruction: a SEER database analysis. J Surg Oncol. 2013 Sep; 108(3):163-8. View in: PubMed

Human breast tissue disposition and bioactivity of limonene in women with early-stage breast cancer. Cancer Prev Res (Phila). 2013 Jun; 6(6):577-84. View in: PubMed

Primary tumor extirpation in breast cancer patients who present with stage IV disease is associated with improved survival. Ann Surg Oncol. 2013 Jun; 20(6):1893-9. View in: PubMed

Aminolevulinic acid (ALA): photodynamic detection and potential therapeutic applications. J Surg Res. 2013 May; 181(2):262-71. View in: PubMed

In Vitro Assessment of the Inflammatory Breast Cancer Cell Line SUM 149: Discovery of 2 Single Nucleotide Polymorphisms in the RNase L Gene. J Cancer. 2013; 4(2):104-16. View in: PubMed

Radiation-induced sarcoma of the breast: a systematic review. Oncologist. 2012; 17(3):405-18. View in: PubMed

Intraoperative frozen section analysis of sentinel lymph nodes in breast cancer patients: a meta-analysis and single-institution experience. Cancer. 2011 Jan 15; 117(2):250-8. View in: PubMed

Ovarian cancer metastatic to the breast presenting as inflammatory breast cancer: a case report and literature review. J Cancer. 2010; 1:27-31. View in: PubMed

Prognostic implications of positive nonsentinel lymph nodes removed during selective sentinel lymphadenectomy for breast cancer. Breast J. 2009 May-Jun; 15(3):242-6. View in: PubMed

HER2 status predicts the presence of circulating tumor cells in patients with operable breast cancer. Breast Cancer Res Treat. 2009 Feb; 113(3):501-7. View in: PubMed

A comparison of RNA amplification techniques at sub-nanogram input concentration. BMC Genomics. 2009; 10:326. View in: PubMed

Is it necessary to harvest additional lymph nodes after resection of the most radioactive sentinel lymph node in breast cancer? J Am Coll Surg. Is it necessary to harvest additional lymph nodes after resection of the most radioactive sentinel lymph node in breast cancer? J Am Coll Surg. 2008 Dec; 207(6):853-8. View in: PubMed

Breast ductal secretions: clinical features, potential uses, and possible applications. Cancer Control. 2007 Oct; 14(4):350-9. View in: PubMed

Significance of micrometastasis in bone marrow and blood of operable breast cancer patients: research tool or clinical application? Expert Rev Anticancer Ther. Significance of micrometastasis in bone marrow and blood of operable breast cancer patients: research tool or clinical application? Expert Rev Anticancer Ther. 2007 Oct; 7(10):1463-72. View in: PubMed

Locoregional Resection in Stage IV breast cancer: tumor biology, molecular and clinical perspectives. Surg Clin North Am. 2007 Apr; 87(2):527-38, xi-xii. View in: PubMed

Accuracy of selective sentinel lymphadenectomy after neoadjuvant chemotherapy: effect of clinical node status at presentation. J Am Coll Surg. 2004 Dec; 199(6):856-62. View in: PubMed

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