Faculty

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Kai Chen, PhD
Associate Professor of Research Radiology
Radiology
CSC 103 Health Sciences Campus Los Angeles
+1 323 442 3582

Publications

Huang R, Conti PS, Chen K. In Vivo Tumor Angiogenesis Imaging Using Peptide-Based Near-Infrared Fluorescent Probes. Methods Mol Biol. 2016; 1444:73-84. View in: PubMed

Jadvar H, Chen K, Ukimura O. Targeted Prostate Gland Biopsy With Combined Transrectal Ultrasound, mpMRI, and 18F-FMAU PET/CT. Clin Nucl Med. 2015 Aug; 40(8):e426-8. View in: PubMed

Huang R, Wang M, Zhu Y, Conti PS, Chen K. Development of PET Probes for Cancer Imaging. Curr Top Med Chem. 2015; 15(8):795-819. View in: PubMed

Ma W, Li G, Wang J, Yang W, Zhang Y, Conti PS, Chen K. In vivo NIRF imaging-guided delivery of a novel NGR-VEGI fusion protein for targeting tumor vasculature. Amino Acids. 2014 Dec; 46(12):2721-32. View in: PubMed

Li G, Wang X, Zong S, Wang J, Conti PS, Chen K. MicroPET Imaging of CD13 Expression Using a (64)Cu-Labeled Dimeric NGR Peptide Based on Sarcophagine Cage. Mol Pharm. 2014 Nov 3; 11(11):3938-46. View in: PubMed

Xing Y, Zhao J, Conti PS, Chen K. Radiolabeled nanoparticles for multimodality tumor imaging. Theranostics. 2014; 4(3):290-306. View in: PubMed

Ma W, Kang F, Wang Z, Yang W, Li G, Ma X, Li G, Chen K, Zhang Y, Wang J. (99m)Tc-labeled monomeric and dimeric NGR peptides for SPECT imaging of CD13 receptor in tumor-bearing mice. Amino Acids. 2013 May; 44(5):1337-45. View in: PubMed

Chen K, Ma W, Li G, Wang J, Yang W, Yap LP, Hughes LD, Park R, Conti PS. Synthesis and evaluation of 64Cu-labeled monomeric and dimeric NGR peptides for MicroPET imaging of CD13 receptor expression. Mol Pharm. 2013 Jan 7; 10(1):417-27. View in: PubMed

Chen K, Wang X, Lin WY, Shen CK, Yap LP, Hughes LD, Conti PS. Strain-Promoted Catalyst-Free Click Chemistry for Rapid Construction of (64)Cu-Labeled PET Imaging Probes. ACS Med Chem Lett. 2012 Dec 13; 3(12):1019-23. View in: PubMed

Chen K, Li Z, Conti PS. Microwave-assisted one-pot radiosynthesis of 2'-deoxy-2'-[(18)F]fluoro-5-methyl-1-ß-d-arabinofuranosyluracil ([(18)F]-FMAU). Nucl Med Biol. 2012 Oct; 39(7):1019-25. View in: PubMed

Jadvar H, Yap LP, Park R, Li Z, Chen K, Hughes L, Kouhi A, Conti P. [18F]-2'-Fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (18F-FMAU) in prostate cancer: initial preclinical observations. Mol Imaging. 2012 Sep-Oct; 11(5):426-32. View in: PubMed

Chen K, Yap LP, Park R, Hui X, Wu K, Fan D, Chen X, Conti PS. A Cy5. 5-labeled phage-displayed peptide probe for near-infrared fluorescence imaging of tumor vasculature in living mice. Amino Acids. 2012 Apr; 42(4):1329-37. View in: PubMed

Chen K, Sun X, Niu G, Ma Y, Yap LP, Hui X, Wu K, Fan D, Conti PS, Chen X. Evaluation of (64)Cu Labeled GX1: A Phage Display Peptide Probe for PET Imaging of Tumor Vasculature. Mol Imaging Biol. 2012 Feb; 14(1):96-105. View in: PubMed

Chen K, Wang X, Lin W, Shen KF, Yap L, Hughes LD, Conti PS. Strain-promoted catalyst-free click chemistry for rapid construction of 64Cu-labeled PET imaging probes. ACS Medicinal Chemistry Letters. 2012; 12(3):1019-1023. View in: PubMed

Li G, Xiang L, Yang W, Wang Z, Wang J, Chen K. Efficient multicistronic co-expression of hNIS and hTPO in prostate cancer cells for nonthyroidal tumor radioiodine therapy. Am J Nucl Med Mol Imaging. 2012; 2(4):483-98. View in: PubMed

Huang CW, Li Z, Cai H, Chen K, Shahinian T, Conti PS. Design, synthesis and validation of integrin a2ß1-targeted probe for microPET imaging of prostate cancer. Eur J Nucl Med Mol Imaging. 2011 Jul; 38(7):1313-22. View in: PubMed

Chen K, Chen X. Positron emission tomography imaging of cancer biology: current status and future prospects. Semin Oncol. 2011 Feb; 38(1):70-86. View in: PubMed

Chen K, Chen X. Integrin targeted delivery of chemotherapeutics. Theranostics. 2011; 1:189-200. View in: PubMed

Chen K, Conti PS. Target-specific delivery of peptide-based probes for PET imaging. Adv Drug Deliv Rev. 2010 Aug 30; 62(11):1005-22. View in: PubMed

Sun X, Niu G, Yan Y, Yang M, Chen K, Ma Y, Chan N, Shen B, Chen X. Phage display-derived peptides for osteosarcoma imaging. Clin Cancer Res. 2010 Aug 15; 16(16):4268-77. View in: PubMed

Anderson CJ, Bulte JW, Chen K, Chen X, Khaw BA, Shokeen M, Wooley KL, VanBrocklin HF. Design of targeted cardiovascular molecular imaging probes. J Nucl Med. 2010 May 1; 51 Suppl 1:3S-17S. View in: PubMed

Chen K, Chen X. Design and development of molecular imaging probes. Curr Top Med Chem. 2010; 10(12):1227-36. View in: PubMed

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