Faculty

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Kiros T. Berhane, PhD
Professor of Preventive Medicine
Head of Epi/Biostatistics Program
Preventive Medicine
SSB 202C 2001 N. Soto Street Health Sciences Campus Los Angeles
+1 323 442 1994

Overview

Dr. Berhane has literally traveled across the globe in pursuit of knowledge. After completing his undergraduate studies at Addis Ababa University, Ethiopia, majoring in statistics, he completed an M.Sc. degree in statistics (University of Guelph, Canada), a Ph.D. degree in biostatistics (University of Toronto, Canada), and a postdoctoral fellowship at Johns Hopkins University (Baltimore, MD). He is currently a Professor in the Division of Biostatistics. His main research interests are in the development of statistical methods for environmental research, and their application to examination of effects of (i) air pollution on children's respiratory and cardiovascular health, and (ii) the built environment on development of childhood obesity.

Awards

Cleveland, Ohio: ENAR Student Award, 1993

University of Toronto, Canada: Whitehall-Robbins Fellow, 1991

Addis Ababa University, Ethiopia: Dean's Honor List, 1982

Publications

Longitudinal Associations Between Ambient Air Pollution with Insulin Sensitivity, ß-Cell Function, and Adiposity in Los Angeles Latino Children. Diabetes. 2017 Jan 30. View in: PubMed

Effects of Childhood Asthma on the Development of Obesity among School-aged Children. Am J Respir Crit Care Med. 2017 Jan 19. View in: PubMed

Electronic-cigarette Use and Respiratory Symptoms in Adolescents. Am J Respir Crit Care Med. 2016 Nov 2. View in: PubMed

E-cigarettes, Cigarettes, and the Prevalence of Adolescent Tobacco Use. Pediatrics. 2016 Aug; 138(2). View in: PubMed

The E-cigarette Social Environment, E-cigarette Use, and Susceptibility to Cigarette Smoking. J Adolesc Health. 2016 Jul; 59(1):75-80. View in: PubMed

E-Cigarettes and Future Cigarette Use. Pediatrics. 2016 Jul; 138(1). View in: PubMed

Environmental Determinants of Aggression in Adolescents: Role of Urban Neighborhood Greenspace. J Am Acad Child Adolesc Psychiatry. 2016 Jul; 55(7):591-601. View in: PubMed

Indoor Air Pollution and Cardiovascular Disease: New Evidence From Iran. Circulation. 2016 Jun 14; 133(24):2342-4. View in: PubMed

Traffic-related air pollution and alveolar nitric oxide in southern California children. Eur Respir J. 2016 May; 47(5):1348-56. View in: PubMed

Association of Changes in Air Quality With Bronchitic Symptoms in Children in California, 1993-2012. JAMA. 2016 Apr 12; 315(14):1491-501. View in: PubMed

Adaptive Set-Based Methods for Association Testing. Genet Epidemiol. 2016 Feb; 40(2):113-22. View in: PubMed

Patterns of Alternative Tobacco Product Use: Emergence of Hookah and E-cigarettes as Preferred Products Amongst Youth. J Adolesc Health. 2016 Feb; 58(2):181-5. View in: PubMed

Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults. PLoS One. 2016; 11(3):e0150825. View in: PubMed

Psychosocial Factors Associated With Adolescent Electronic Cigarette and Cigarette Use. Pediatrics. 2015 Aug; 136(2):308-17. View in: PubMed

A Longitudinal Cohort Study of Body Mass Index and Childhood Exposure to Secondhand Tobacco Smoke and Air Pollution: The Southern California Children's Health Study. Environ Health Perspect. 2015 Apr; 123(4):360-6. View in: PubMed

Association of improved air quality with lung development in children. N Engl J Med. 2015 Mar 5; 372(10):905-13. View in: PubMed

Spirometry effects on conventional and multiple flow exhaled nitric oxide in children. J Asthma. 2015 Mar; 52(2):198-204. View in: PubMed

Determinants of Children's Exhaled Nitric Oxide: New Insights from Quantile Regression. PLoS One. 2015; 10(7):e0130505. View in: PubMed

Inflammatory response of monocytes to ambient particles varies by highway proximity. Am J Respir Cell Mol Biol. 2014 Dec; 51(6):802-9. View in: PubMed

Quantile Mediation Models: A Comparison of Methods for Assessing Mediation Across the Outcome Distribution. Multivariate Behav Res. 2014 Sep-Oct; 49(5):471-85. View in: PubMed

Fraction of exhaled nitric oxide values in childhood are associated with 17q11. 2-q12 and 17q12-q21 variants. J Allergy Clin Immunol. 2014 Jul; 134(1):46-55. View in: PubMed

Longitudinal effects of air pollution on exhaled nitric oxide: the Children's Health Study. Occup Environ Med. 2014 Jul; 71(7):507-13. View in: PubMed

Bayesian mixed hidden Markov models: a multi-level approach to modeling categorical outcomes with differential misclassification. Stat Med. 2014 Apr 15; 33(8):1395-408. View in: PubMed

Estimation of parameters in the two-compartment model for exhaled nitric oxide. PLoS One. 2014 Jan 17; 9(1):e85471. View in: PubMed

Traffic-related air pollution and obesity formation in children: a longitudinal, multilevel analysis. Environ Health. 2014; 13:49. View in: PubMed

Multiple-flow exhaled nitric oxide, allergy, and asthma in a population of older children. Pediatr Pulmonol. 2013 Sep; 48(9):885-96. View in: PubMed

Factors influencing whether children walk to school. Health Place. 2013 Jul; 22:153-61. View in: PubMed

Response to letter regarding article, “Childhood air pollutant exposure and carotid artery intima–media thickness in young adults”. Circulation. 2013 Jun 4; 127(22):e659. View in: PubMed

Inflammatory cytokine response to ambient particles varies due to field collection procedures. Am J Respir Cell Mol Biol. 2013 Apr; 48(4):497-502. View in: PubMed

Household endotoxin levels and the risk of non-Hodgkin lymphoma. Cancer Causes Control. 2013 Feb; 24(2):357-64. View in: PubMed

Prenatal exposure to urban air nanoparticles in mice causes altered neuronal differentiation and depression-like responses. PLoS One. 2013; 8(5):e64128. View in: PubMed

Childhood air pollutant exposure and carotid artery intima-media thickness in young adults. Circulation. 2012 Sep 25; 126(13):1614-20. View in: PubMed

Organized physical activity in young school children and subsequent 4-year change in body mass index. Arch Pediatr Adolesc Med. 2012 Aug 1; 166(8):713-8. View in: PubMed

Randomized controlled trial to improve adiposity, inflammation, and insulin resistance in obese african-american and latino youth. Obesity (Silver Spring). 2012 Apr; 20(4):811-8. View in: PubMed

Predictors of intra-community variation in air quality. J Expo Sci Environ Epidemiol. 2012 Mar; 22(2):135-47. View in: PubMed

Allergic inflammation in the human lower respiratory tract affected by exposure to diesel exhaust. Res Rep Health Eff Inst. 2012 Feb; (165):5-43; discussion 45-64. View in: PubMed

Cryptorchidism and testicular germ cell tumors: comprehensive meta-analysis reveals that association between these conditions diminished over time and is modified by clinical characteristics. Front Endocrinol (Lausanne). 2012; 3:182. View in: PubMed

Social environment and asthma: associations with crime and No Child Left Behind programmes. J Epidemiol Community Health. 2011 Oct; 65(10):859-65. View in: PubMed

Residential traffic-related pollution exposures and exhaled nitric oxide in the children's health study. Environ Health Perspect. 2011 Oct; 119(10):1472-7. View in: PubMed

Carotid artery intima-media thickness in college students: race/ethnicity matters. Atherosclerosis. 2011 Aug; 217(2):441-6. View in: PubMed

The effect of ambient air pollution on exhaled nitric oxide in the Children's Health Study. Eur Respir J. 2011 May; 37(5):1029-36. View in: PubMed

Ethnic differences in the effect of asthma on pulmonary function in children. Am J Respir Crit Care Med. 2011 Mar 1; 183(5):596-603. View in: PubMed

Childhood obesity and proximity to urban parks and recreational resources: A longitudinal cohort study. Health Place. 2011 Jan; 17(1):207-14. View in: PubMed

Asthma and school commuting time. J Occup Environ Med. 2010 Aug; 52(8):827-8. View in: PubMed

Childhood incident asthma and traffic-related air pollution at home and school. Environ Health Perspect. 2010 Jul; 118(7):1021-6. View in: PubMed

Increased physical activity and reduced adiposity in overweight Hispanic adolescents. Med Sci Sports Exerc. 2010 Mar; 42(3):478-84. View in: PubMed

Automobile traffic around the home and attained body mass index: a longitudinal cohort study of children aged 10-18 years. Prev Med. 2010 Jan; 50 Suppl 1:S50-8. View in: PubMed

Functional variants in the catalase and myeloperoxidase genes, ambient air pollution, and respiratory-related school absences: an example of epistasis in gene-environment interactions. Am J Epidemiol. 2009 Dec 15; 170(12):1494-501. View in: PubMed

Relationships of online exhaled, offline exhaled, and ambient nitric oxide in an epidemiologic survey of schoolchildren. J Expo Sci Environ Epidemiol. 2009 Nov; 19(7):674-81. View in: PubMed

Extended exhaled nitric oxide analysis in field surveys of schoolchildren: a pilot test. Pediatr Pulmonol. 2009 Oct; 44(10):1033-42. View in: PubMed

Randomized control trial to improve adiposity and insulin resistance in overweight Latino adolescents. Obesity (Silver Spring). 2009 Aug; 17(8):1542-8. View in: PubMed

Parental stress increases the effect of traffic-related air pollution on childhood asthma incidence. Proc Natl Acad Sci U S A. 2009 Jul 28; 106(30):12406-11. View in: PubMed

In utero smoke exposure, glutathione S-transferase P1 haplotypes, and respiratory illness-related absence among schoolchildren. Pediatrics. 2009 May; 123(5):1344-51. View in: PubMed

Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung function. Am J Respir Crit Care Med. 2009 Apr 1; 179(7):601-7. View in: PubMed

Exhaled nitric oxide in a population-based study of southern California schoolchildren. Respir Res. 2009; 10:28. View in: PubMed

Using tensor product splines in modeling exposure-time-response relationships: application to the Colorado Plateau Uranium Miners cohort. Stat Med. 2008 Nov 20; 27(26):5484-96. View in: PubMed

Traffic-related air pollution and asthma onset in children: a prospective cohort study with individual exposure measurement. Environ Health Perspect. 2008 Oct; 116(10):1433-8. View in: PubMed

A Bayesian approach to functional-based multilevel modeling of longitudinal data: applications to environmental epidemiology. Biostatistics. 2008 Oct; 9(4):686-99. View in: PubMed

Parental stress and childhood wheeze in a prospective cohort study. J Asthma. 2008 May; 45(4):319-23. View in: PubMed

Traffic-related exposures, airway function, inflammation, and respiratory symptoms in children. Am J Respir Crit Care Med. 2007 Dec 15; 176(12):1236-42. View in: PubMed

Relationship between air pollution, lung function and asthma in adolescents. Thorax. 2007 Nov; 62(11):957-63. View in: PubMed

The association between contextual socioeconomic factors and prevalent asthma in a cohort of Southern California school children. Soc Sci Med. 2007 Oct; 65(8):1792-806. View in: PubMed

Assessing uncertainty in spatial exposure models for air pollution health effects assessment. Environ Health Perspect. 2007 Aug; 115(8):1147-53. View in: PubMed

Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study. Lancet. 2007 Feb 17; 369(9561):571-7. View in: PubMed

Dog ownership enhances symptomatic responses to air pollution in children with asthma. Environ Health Perspect. 2006 Dec; 114(12):1910-5. View in: PubMed

Health effects of the 2003 Southern California wildfires on children. Am J Respir Crit Care Med. 2006 Dec 1; 174(11):1221-8. View in: PubMed

Regular smoking and asthma incidence in adolescents. Am J Respir Crit Care Med. 2006 Nov 15; 174(10):1094-100. View in: PubMed

Bayesian modeling of air pollution health effects with missing exposure data. Am J Epidemiol. 2006 Jul 1; 164(1):69-76. View in: PubMed

Predicting residential ozone deficits from nearby traffic. Sci Total Environ. 2006 Jun 15; 363(1-3):166-74. View in: PubMed

Traffic, susceptibility, and childhood asthma. Environ Health Perspect. 2006 May; 114(5):766-72. View in: PubMed

Exposure to environmental ozone alters semen quality. Environ Health Perspect. 2006 Mar; 114(3):360-5. View in: PubMed

TNF-308 modifies the effect of second-hand smoke on respiratory illness-related school absences. Am J Respir Crit Care Med. 2005 Dec 15; 172(12):1563-8. View in: PubMed

A three-level model for binary time-series data: the effects of air pollution on school absences in the Southern California Children's Health Study. Stat Med. 2005 Apr 15; 24(7):1103-15. View in: PubMed

Impact of highly active antiretroviral therapy on anemia and relationship between anemia and survival in a large cohort of HIV-infected women: Women's Interagency HIV Study. J Acquir Immune Defic Syndr. 2004 Oct 1; 37(2):1245-52. View in: PubMed

Effects of ambient air pollutants on asthma medication use and wheezing among fourth-grade school children from 12 Southern California communities enrolled in The Children's Health Study. Arch Environ Health. 2004 Oct; 59(10):505-14. View in: PubMed

The effect of air pollution on lung development from 10 to 18 years of age. N Engl J Med. 2004 Sep 9; 351(11):1057-67. View in: PubMed

Inference in spline-based models for multiple time-to-event data, with applications to a breast cancer prevention trial. Biometrics. 2003 Dec; 59(4):859-68. View in: PubMed

Cockroach counts and house dust allergen concentrations after professional cockroach control and cleaning. Ann Allergy Asthma Immunol. 2003 Dec; 91(6):546-52. View in: PubMed

Prospective study of air pollution and bronchitic symptoms in children with asthma. Am J Respir Crit Care Med. 2003 Oct 1; 168(7):790-7. View in: PubMed

Children's lung function and antioxidant vitamin, fruit, juice, and vegetable intake. Am J Epidemiol. 2003 Sep 15; 158(6):576-84. View in: PubMed

Obesity and the risk of newly diagnosed asthma in school-age children. Am J Epidemiol. 2003 Sep 1; 158(5):406-15. View in: PubMed

Effects of early onset asthma and in utero exposure to maternal smoking on childhood lung function. Am J Respir Crit Care Med. 2003 Mar 15; 167(6):917-24. View in: PubMed

Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children. Am J Respir Crit Care Med. 2002 Aug 15; 166(4):457-63. View in: PubMed

Effects of glutathione S-transferase P1, M1, and T1 on acute respiratory illness in school children. Am J Respir Crit Care Med. 2002 Aug 1; 166(3):346-51. View in: PubMed

Association between air pollution and lung function growth in southern California children: results from a second cohort. Am J Respir Crit Care Med. 2002 Jul 1; 166(1):76-84. View in: PubMed

Indoor risk factors for asthma in a prospective study of adolescents. Epidemiology. 2002 May; 13(3):288-95. View in: PubMed

A two-stage model for multiple time series data of counts. Biostatistics. 2002 Mar; 3(1):21-32. View in: PubMed

Asthma in exercising children exposed to ozone: a cohort study. Lancet. 2002 Feb 2; 359(9304):386-91. View in: PubMed

Dietary magnesium, potassium, sodium, and children's lung function. Am J Epidemiol. 2002 Jan 15; 155(2):125-31. View in: PubMed

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