Director, Division of Women's Imaging
Director, Radiology Research in Women's Health
Dr. Linda Hovanessian Larsen, M.D. was born and raised in Los Angeles, California. Upon completion of medical school, she began her residency in Diagnostic Radiology at UCLA and her fellowship training in Breast Imaging at Mount Sinai Medical Center, Miami, Florida.
Dr. Hovanessian Larsen first began her career working at the University of Miami Medical Center, specializing in breast imaging. She joined the faculty of the USC Keck School of Medicine in 1998, and became the Director of Outpatient Mammography for the LAC+USC Medical Center and the Director of Women’s Imaging for the Department of Radiology (DOR). She has served on administrative and clinical committees for the DOR, and has spearheaded many of the Woman’s Imaging research projects. She incorporated the USC DOR into the American College of Radiology Imaging Network (ACRIN), which is a national multicenter organization supported in part by the National Cancer Institute. In addition to her full-time clinical responsibilities, she participates in local and national breast imaging meetings, lectures to the radiology residents, and is the director of the Women’s Imaging fellowship at USC.
Dr. Hovanessian Larsen is a respected consultant for a number of breast cancer screening initiatives, as well as a recognized leader in mammography interpretation and breast biopsy. She has received significant grant awards from the Susan G. Komen Breast Cancer Foundation and the Whittier foundation. She has been involved in several multi-center trials including the NCI, ACRIN, I-SPY 2, and SWOG. Dr. Hovanessian Larsen is dedicated to improving the diagnosis and treatment of breast cancer through early detection, heightened awareness of risk factors, and developing improved imaging methods. Her area of interest is new breast imaging modalities, including digital breast tomosynthesis, automated whole breast ultrasound, and contrast enhanced breast ultrasound.
Khadem N, Reddy S, Lee S, Larsen L, Walker D. ED breast cases and other breast emergencies. Emerg Radiol. 2016 Feb; 23(1):67-77. View in: PubMed
Silberman H, Sheth PA, Parisky YR, Hovanessian-Larsen LJ, Sheth S, Tripathy D. Modified Bi-Rads Scoring of Breast Imaging Findings Improves Clinical Judgment. Breast J. 2015 Nov; 21(6):642-50. View in: PubMed
Cummins T, Yoon C, Choi H, Eliahoo P, Kim HH, Yamashita MW, Hovanessian-Larsen LJ, Lang JE, Sener SF, Vallone J, Martin SE, Kirk Shung K. High-frequency ultrasound imaging for breast cancer biopsy guidance. J Med Imaging (Bellingham). 2015 Oct; 2(4):047001. View in: PubMed
Wu AH, Spicer D, Garcia A, Tseng CC, Hovanessian-Larsen L, Sheth P, Martin SE, Hawes D, Russell C, MacDonald H, Tripathy D, Su MY, Ursin G, Pike MC. Double-Blind Randomized 12-Month Soy Intervention Had No Effects on Breast MRI Fibroglandular Tissue Density or Mammographic Density. Cancer Prev Res (Phila). 2015 Oct; 8(10):942-51. View in: PubMed
Yamashita M, Hovanessian-Larsen L, Sener SF. The role of axillary ultrasound in the detection of metastases from primary breast cancers. Am J Surg. 2013 Mar; 205(3):242-4; discussion 244-5. View in: PubMed
Hovanessian-Larsen L, Taylor D, Hawes D, Spicer DV, Press MF, Wu AH, Pike MC, Pearce CL. Lowering oral contraceptive norethindrone dose increases estrogen and progesterone receptor levels with no reduction in proliferation of breast epithelium: a randomized trial. Contraception. 2012 Sep; 86(3):238-43. View in: PubMed
Berg WA, Zhang Z, Lehrer D, Jong RA, Pisano ED, Barr RG, Böhm-Vélez M, Mahoney MC, Evans WP, Larsen LH, Morton MJ, Mendelson EB, Farria DM, Cormack JB, Marques HS, Adams A, Yeh NM, Gabrielli G. Detection of breast cancer with addition of annual screening ultrasound or a single screening MRI to mammography in women with elevated breast cancer risk. JAMA. 2012 Apr 4; 307(13):1394-404. View in: PubMed
Berg W, Madsen K, Schilling K, Tartar M, Pisano E, Hovanessian Larsen L, et al. . Breast Cancer: Comparative Effectiveness of Positron Emission Mammography and MR imaging in Presurgical Planning for the Ipsilateral Breast. Radiology. 2011; 1(258):59-72. View in: PubMed
Berg W, Blume J, Adams A, Jong R, Barr R, Lehrer D, Pisano E, Evans W, Mahoney M, Hovanessian Larsen L, Gabrielli G, Mendelson E. Reasons Women at Elevated Risk of Breast Cancer Refuse Screening Breast MRI: ACRIN 6666. Radiology. 2010; 1(254):79-87. View in: PubMed
Hovanessian Larsen LJ, Peyvandi B, Klipfel N, Grant E, Iyengar G. Granulomatous lobular mastitis: imaging, diagnosis, and treatment. AJR Am J Roentgenol. 2009 Aug; 193(2):574-81. View in: PubMed