Dr. Shao's major areas of research interest are inflammatory bowel disease, intestinal epithelial cells, inflammation and immunology. His current research involves the ubiquitin editing enzyme A20 preserves intestinal epithelial cell homeostasis.
Dr. Shao earned his medical degree from The Mount Sinai School of Medicine. He then performed his residency at University of California, San Francisco, and then stayed on to complete a Gastroenterology Fellowship.
The Mount Sinai School of Medicine: The Mount Sinai Student Council Teamwork Award, 2006
The Mount Sinai School of Medicine: The Mount Sinai Graduate School Service Award, 2003
Inflammatory Bowel Disease Working Group: The Inflammatory Bowel Disease Working Group Fellowship Award, 2012
Division of Gastroenterology and Liver Diseases, USC: GI Fellows Teaching Award, 2015
The Jeffrey Modell Foundation: The Jeffrey Modell Foundation Award, 2005
The Arnold P. Gold Foundation: The Arnold P. Gold Humanism Honor Society, 2006
Peng P, Lekadir K, Gooya A, Shao L, Petersen SE, Frangi AF. A review of heart chamber segmentation for structural and functional analysis using cardiac magnetic resonance imaging. MAGMA. 2016 Apr; 29(2):155-95. View in: PubMed
Rogers RL, Cridland JM, Shao L, Hu TT, Andolfatto P, Thornton KR. Tandem Duplications and the Limits of Natural Selection in Drosophila yakuba and Drosophila simulans. PLoS One. 2015; 10(7):e0132184. View in: PubMed
Chirra HD, Shao L, Ciaccio N, Fox CB, Wade JM, Ma A, Desai TA. Planar microdevices for enhanced in vivo retention and oral bioavailability of poorly permeable drugs. Adv Healthc Mater. 2014 Oct; 3(10):1648-54. View in: PubMed
Shao L, Oshima S, Duong B, Advincula R, Barrera J, Malynn BA, Ma A. A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis. PLoS One. 2013; 8(5):e62223. View in: PubMed
Carlton PM, Boulanger J, Kervrann C, Sibarita JB, Salamero J, Gordon-Messer S, Bressan D, Haber JE, Haase S, Shao L, Winoto L, Matsuda A, Kner P, Uzawa S, Gustafsson M, Kam Z, Agard DA, Sedat JW. Fast live simultaneous multiwavelength four-dimensional optical microscopy. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16016-22. View in: PubMed
Matsuda A, Shao L, Boulanger J, Kervrann C, Carlton PM, Kner P, Agard D, Sedat JW. Condensed mitotic chromosome structure at nanometer resolution using PALM and EGFP- histones. PLoS One. 2010; 5(9):e12768. View in: PubMed
Shao L, Isaac B, Uzawa S, Agard DA, Sedat JW, Gustafsson MG. I5S: wide-field light microscopy with 100-nm-scale resolution in three dimensions. Biophys J. 2008 Jun; 94(12):4971-83. View in: PubMed
Chen J, Galt JR, Case JA, Ye J, Cullom SJ, Durbin MK, Shao L, Garcia EV. Transmission scan truncation with small-field-of-view dedicated cardiac SPECT systems: impact and automated quality control. J Nucl Cardiol. 2005 Sep-Oct; 12(5):567-73. View in: PubMed