Faculty

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Mark S. Humayun, MD, PhD
University Professor of Ophthalmology
Cornelius J. Pings Chair in Biomedical Sciences
Director, Institute For Biomedical Therapeutics
Co Director USC Eye Institute
Director of Sensory Science Initiatives
Ophthalmology
HC4 6534B 1450 San Pablo Street Off Campus Los Angeles
+1 323 865 3092

Overview

Mark S. Humayun, MD, PhD, received his Bachelors of Science degree from Georgetown University in 1984, his Masters Doctorate from Duke University in 1989, and his PhD from the University of North Carolina, Chapel Hill in 1994. He completed his ophthalmology residency at Duke Eye Center and fellowships in both vitreoretinal and retinovascular surgery at Johns Hopkins Hospital. He stayed on as faculty at Johns Hopkins where he rose to the rank of associate professor before moving to USC in 2001.

Dr. Humayun has devoted much of his career to clinical and scientific research in ophthalmology and bioengineering, becoming both a biomedical engineer and professor of ophthalmology. Dr. Humayun led a talented and diverse team of interdisciplinary researchers with the ultimate goal of creating the world’s first artificial retina. He assembled a team of world experts with a wide range of proficiency, including biomedical engineering, computer science, medicine, chemistry, biology and business. In clinical trials since 2007 and approved by the FDA in 2013, the Argus II retinal implant, represents the culmination of a visual restoration strategy that offers an unprecedented degree of sight to those with complete retinal blindness. He was elected to the prestigious National Academy of Medicine (NAM) and National Academy of Engineering (NAE) for his pioneering work to restore sight.

With over 200 publications and more than 100 patents and patent applications, Dr. Humayun has received several research awards which includes the 2005 Innovator of the Year award. He was also featured as one of the top 10 inventors in Time Magazine in 2013, voted as one of the Best Doctors in America for three years, and one of the top 1% of Doctors by U.S. News & World Report.

In 2016, Dr. Humayun received the National Medal of Technology and Innovation from President Barack Obama for his innovative work and development of the Argus II.

Awards

National Academy of Inventors Fellows Medallion

USC Presidential Medallion

National Medal of Technology and Innovation

Wills Eye Institute: Richard Ellis Award, 2014

Pasadena Magazine: Top Doctors in Ophthalmology, 2013-2014

UIC Illinois Eye and Ear Infirmary: Morton F. Goldberg Endowed Lecturer Medallion, 2013

Castle Connolly Medical Ltd. : America's Top Doctors, 2011

U.S. World & News Report: Top 1% of Ophthalmologists, 2011

Popular Mechanics Breakthrough Award

The Retina Society: Award of Merit in Retina Research, 2009

Best Doctors in Southern California Award

Best Doctors of America Award

Strathmore's Who's Who Award

R&D magazine: Innovator of the Year award, 2005

Senior Honor Award of the Am. Soc. Retina Specialists

Jules Stein Living tribute Award

William and Mary Grieve Scholar's Award

Richard S. Ross Clinical Scientist Award

Publications

Parylene scaffold for cartilage lesion. Biomed Microdevices. 2017 Jun; 19(2):26. View in: PubMed

THE SECOND BLIND SPOT: SMALL RETINAL VESSEL VASCULOPATHY AFTER VACCINATION AGAINST NEISSERIA MENINGITIDIS AND YELLOW FEVER. Retin Cases Brief Rep. 2017 Winter; 11 Suppl 1:S18-S23. View in: PubMed

Five-Year Safety and Performance Results from the Argus II Retinal Prosthesis System Clinical Trial. Ophthalmology. 2016 Oct; 123(10):2248-54. View in: PubMed

The Bionic Eye: A Quarter Century of Retinal Prosthesis Research and Development. Ophthalmology. 2016 Oct; 123(10S):S89-S97. View in: PubMed

Strategies to improve stimulation efficiency for retinal prostheses. Conf Proc IEEE Eng Med Biol Soc. 2016 Aug; 2016:3133-3138. View in: PubMed

Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs. Graefes Arch Clin Exp Ophthalmol. 2016 Aug; 254(8):1553-65. View in: PubMed

Retinal stimulation strategies to restore vision: Fundamentals and systems. Prog Retin Eye Res. 2016 Jul; 53:21-47. View in: PubMed

INTRAOCULAR PRESSURE CHANGES DURING VITRECTOMY USING CONSTELLATION VISION SYSTEM'S INTRAOCULAR PRESSURE CONTROL FEATURE. Retina. 2016 Jul; 36(7):1275-80. View in: PubMed

Biomimetic Accommodating Intraocular Lens Using a Valved Deformable Liquid Balloon. IEEE Trans Biomed Eng. 2016 Jun; 63(6):1129-35. View in: PubMed

Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats. Invest Ophthalmol Vis Sci. 2016 May 1; 57(6):2877-87. View in: PubMed

An Innovative Surgical Technique for Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium in Yucatan Mini Pigs: Preliminary Results. Ophthalmic Surg Lasers Imaging Retina. 2016 Apr 1; 47(4):342-51. View in: PubMed

NorLeu3A(1-7) Accelerates Clear Corneal Full Thickness Wound Healing. Invest Ophthalmol Vis Sci. 2016 Apr 1; 57(4):2187-94. View in: PubMed

Spatial Variations in Vitreous Oxygen Consumption. PLoS One. 2016; 11(3):e0149961. View in: PubMed

OPTOMAP WIDEFIELD IMAGING OF THE ARGUS II RETINAL PROSTHESIS IN PATIENTS WITH RETINITIS PIGMENTOSA. Retin Cases Brief Rep. 2016; 10(4):382-5. View in: PubMed

Improving the spatial resolution of epiretinal implants by increasing stimulus pulse duration. Sci Transl Med. 2015 Dec 16; 7(318):318ra203. View in: PubMed

Ten-Year Follow-up of a Blind Patient Chronically Implanted with Epiretinal Prosthesis Argus I. Ophthalmology. 2015 Dec; 122(12):2545-2552. e1. View in: PubMed

Stem cell based therapies for age-related macular degeneration: The promises and the challenges. Prog Retin Eye Res. 2015 Sep; 48:1-39. View in: PubMed

Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind. Ophthalmology. 2015 Aug; 122(8):1547-54. View in: PubMed

Monte Carlo analysis of the enhanced transcranial penetration using distributed near-infrared emitter array. J Biomed Opt. 2015 Aug 1; 20(8):88001. View in: PubMed

Fluidics comparison between dual pneumatic and spring return high-speed vitrectomy systems. Ophthalmic Surg Lasers Imaging Retina. 2015 Jan 1; 46(1):68-72. View in: PubMed

Whole Vitreous Humor Dissection for Vitreodynamic Analysis. J Vis Exp. 2015; (99). View in: PubMed

Implantable MicroPump for Drug Delivery in Patients with Diabetic Macular Edema. Transl Vis Sci Technol. 2014 Oct; 3(6):5. View in: PubMed

NONINVASIVE ASSESSMENT OF RETINAL VASCULAR OXYGEN CONTENT AMONG NORMAL AND DIABETIC HUMAN SUBJECTS: A Study Using Hyperspectral Computed Tomographic Imaging Spectroscopy. Retina. 2014 Sep; 34(9):1854-60. View in: PubMed

Elastic properties of human posterior eye. J Biomed Mater Res A. 2014 Jun; 102(6):2001-7. View in: PubMed

Retinal prosthesis. IEEE Trans Biomed Eng. 2014 May; 61(5):1412-24. View in: PubMed

One-Year Feasibility Study of Replenish MicroPump for Intravitreal Drug Delivery: A Pilot Study. Transl Vis Sci Technol. 2014 May; 3(4):8. View in: PubMed

Interphase gap as a means to reduce electrical stimulation thresholds for epiretinal prostheses. J Neural Eng. 2014 Feb; 11(1):016007. View in: PubMed

Microdevice-based cell therapy for age-related macular degeneration. Dev Ophthalmol. 2014; 53:155-66. View in: PubMed

Comparison of Reaction Response Time between Hand and Foot Controlled Devices in Simulated Microsurgical Testing. Biomed Res Int. 2014; 2014:769296. View in: PubMed

Profile of ocriplasmin and its potential in the treatment of vitreomacular adhesion. Clin Ophthalmol. 2014; 8:847-56. View in: PubMed

A fully intraocular high-density self-calibrating epiretinal prosthesis. IEEE Trans Biomed Circuits Syst. 2013 Dec; 7(6):747-60. View in: PubMed

In vivo detection of hESC-RPE cells via confocal near-infrared fundus reflectance. Ophthalmic Surg Lasers Imaging Retina. 2013 Jul-Aug; 44(4):380-4. View in: PubMed

Subretinal implantation of retinal pigment epithelial cells derived from human embryonic stem cells: improved survival when implanted as a monolayer. Invest Ophthalmol Vis Sci. 2013 Jul; 54(7):5087-96. View in: PubMed

A system verification platform for high-density epiretinal prostheses. IEEE Trans Biomed Circuits Syst. 2013 Jun; 7(3):326-37. View in: PubMed

Analysis of a 23-gauge ultra high-speed cutter with duty cycle control. Retina. 2013 May; 33(5):933-8. View in: PubMed

Performance analysis of ultrahigh-speed vitreous cutter system. Retina. 2013 May; 33(5):928-32. View in: PubMed

The Argus II epiretinal prosthesis system allows letter and word reading and long-term function in patients with profound vision loss. Br J Ophthalmol. 2013 May; 97(5):632-6. View in: PubMed

Light-triggered modulation of cellular electrical activity by ruthenium diimine nanoswitches. ACS Chem Neurosci. 2013 Apr 17; 4(4):585-93. View in: PubMed

Imaging the response of the retina to electrical stimulation with genetically encoded calcium indicators. J Neurophysiol. 2013 Apr; 109(7):1979-88. View in: PubMed

Quantitative analysis of retinal structures using spectral domain optical coherence tomography in normal rabbits. Curr Eye Res. 2013 Feb; 38(2):299-304. View in: PubMed

Fluidics in a dual pneumatic ultra high-speed vitreous cutter system. Ophthalmologica. 2013; 229(1):15-20. View in: PubMed

In vivo Sonothrombolysis of Ear Marginal Vein of Rabbits Monitored with High-frequency Ultrasound Needle Transducer. J Med Biol Eng. 2013; 33(1):103-110. View in: PubMed

High-resolution OCT: an innovative tool for posterior segment imaging. Ophthalmic Surg Lasers Imaging. 2012 Nov-Dec; 43(6 Suppl):S123-34. View in: PubMed

Fluorescein angiography, optical coherence tomography, and histopathologic findings in a VEGF(165) animal model of retinal angiogenesis. Graefes Arch Clin Exp Ophthalmol. 2012 Oct; 250(10):1421-8. View in: PubMed

Mesh-supported submicron parylene-C membranes for culturing retinal pigment epithelial cells. Biomed Microdevices. 2012 Aug; 14(4):659-67. View in: PubMed

Artificial vision through neuronal stimulation. Neurosci Lett. 2012 Jun 25; 519(2):122-8. View in: PubMed

Preservation of retinotopic map in retinal degeneration. Exp Eye Res. 2012 May; 98:88-96. View in: PubMed

Interim Results from the International Trial of Second Sight's Visual Prosthesis. Ophthalmology. 2012 Apr; 119(4):779-88. View in: PubMed

Assessment of MRI issues for the Argus II Retinal Prosthesis. Magn Reson Imaging. 2012 Apr; 30(3):382-9. View in: PubMed

A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Res. 2012; 48(4):186-91. View in: PubMed

Acute variations in retinal vascular oxygen content in a rabbit model of retinal venous occlusion. PLoS One. 2012; 7(11):e50179. View in: PubMed

Frequency and amplitude modulation have different effects on the percepts elicited by retinal stimulation. Invest Ophthalmol Vis Sci. 2012; 53(1):205-14. View in: PubMed

Evaluation of ultrasound-assisted thrombolysis using custom liposomes in a model of retinal vein occlusion. Invest Ophthalmol Vis Sci. 2012; 53(11):6920-7. View in: PubMed

Impedance as a method to sense proximity at the electrode-retina interface. IEEE Trans Neural Syst Rehabil Eng. 2011 Dec; 19(6):696-9. View in: PubMed

Retinal prostheses: current clinical results and future needs. Ophthalmology. 2011 Nov; 118(11):2227-37. View in: PubMed

Resolution of the epiretinal prosthesis is not limited by electrode size. IEEE Trans Neural Syst Rehabil Eng. 2011 Aug; 19(4):436-42. View in: PubMed

Modeling and percept of transcorneal electrical stimulation in humans. IEEE Trans Biomed Eng. 2011 Jul; 58(7):1932-9. View in: PubMed

Both electrical stimulation thresholds and SMI-32-immunoreactive retinal ganglion cell density correlate with age in S334ter line 3 rat retina. J Neurophysiol. 2011 Jun; 105(6):2687-97. View in: PubMed

Morphometric analysis of optic nerves and retina from an end-stage retinitis pigmentosa patient with an implanted active epiretinal array. Invest Ophthalmol Vis Sci. 2011 Jun; 52(7):4610-6. View in: PubMed

Performance analysis of millennium vitreous enhancer™ system. Ophthalmic Surg Lasers Imaging. 2011 Mar-Apr; 42(3):162-7. View in: PubMed

Vitreal oxygenation in retinal ischemia reperfusion. Invest Ophthalmol Vis Sci. 2011 Feb; 52(2):1035-42. View in: PubMed

Hyperspectral computed tomographic imaging spectroscopy of vascular oxygen gradients in the rabbit retina in vivo. PLoS One. 2011; 6(9):e24482. View in: PubMed

A new dual port cutter system for vitrectomy surgery. Retina. 2010 Oct; 30(9):1515-9. View in: PubMed

Novel method to quantify traction in a vitrectomy procedure. Br J Ophthalmol. 2010 Sep; 94(9):1226-9. View in: PubMed

An experimental protocol of the model to quantify traction applied to the retina by vitreous cutters. Invest Ophthalmol Vis Sci. 2010 Aug; 51(8):4181-6. View in: PubMed

Vitreoretinal traction created by conventional cutters during vitrectomy. Ophthalmology. 2010 Jul; 117(7):1387-92. e2. View in: PubMed

Ultrasonic Doppler measurements of blood flow velocity of rabbit retinal vessels using a 45-MHz needle transducer. Graefes Arch Clin Exp Ophthalmol. 2010 May; 248(5):675-80. View in: PubMed

Effect of multiple injections of small divided doses vs single injection of intravitreal bevacizumab on retinal neovascular model in rabbits. Graefes Arch Clin Exp Ophthalmol. 2010 Apr; 248(4):457-66. View in: PubMed

Mini drug pump for ophthalmic use. Curr Eye Res. 2010 Mar; 35(3):192-201. View in: PubMed

Blood velocity measurement in the posterior segment of the rabbit eye using combined spectral Doppler and power Doppler ultrasound. Graefes Arch Clin Exp Ophthalmol. 2010 Jan; 248(1):93-101. View in: PubMed

Mini drug pump for ophthalmic use. Trans Am Ophthalmol Soc. 2009 Dec; 107:60-70. View in: PubMed

Brightness as a function of current amplitude in human retinal electrical stimulation. Invest Ophthalmol Vis Sci. 2009 Nov; 50(11):5017-25. View in: PubMed

Measurements of attenuation coefficient for evaluating the hardness of a cataract lens by a high-frequency ultrasonic needle transducer. Phys Med Biol. 2009 Oct 7; 54(19):5981-94. View in: PubMed

A passive MEMS drug delivery pump for treatment of ocular diseases. Biomed Microdevices. 2009 Oct; 11(5):959-70. View in: PubMed

Conjunctival impression cytology by using a thermosensitive adhesive: polymerized N-isopropyl acrylamide. Cornea. 2009 Aug; 28(7):770-3. View in: PubMed

Toward a wide-field retinal prosthesis. J Neural Eng. 2009 Jun; 6(3):035002. View in: PubMed

Selective labeling of retinal ganglion cells with calcium indicators by retrograde loading in vitro. J Neurosci Methods. 2009 May 15; 179(2):166-72. View in: PubMed

Feasibility study of a retinal prosthesis: spatial vision with a 16-electrode implant. Arch Ophthalmol. 2009 Apr; 127(4):398-401. View in: PubMed

Predicting visual sensitivity in retinal prosthesis patients. Invest Ophthalmol Vis Sci. 2009 Apr; 50(4):1483-91. View in: PubMed

Feasibility of rotational scan ultrasound imaging by an angled high frequency transducer for the posterior segment of the eye. IEEE Trans Ultrason Ferroelectr Freq Control. 2009 Mar; 56(3):676-80. View in: PubMed

Immunocytochemical analysis of retinal neurons under electrical stimulation. Brain Res. 2009 Feb 19; 1255:89-97. View in: PubMed

Metabolic prosthesis for oxygenation of ischemic tissue. IEEE Trans Biomed Eng. 2009 Feb; 56(2):528-31. View in: PubMed

Artificial vision: needs, functioning, and testing of a retinal electronic prosthesis. Prog Brain Res. 2009; 175:317-32. View in: PubMed

Biomimetic image processing for retinal prostheses: peripheral saliency cues. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:4569-72. View in: PubMed

A comparison of retinal prosthesis electrode array substrate materials. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:4140-3. View in: PubMed

Guillotine performance: duty cycle analysis of vitrectomy systems. Retin Cases Brief Rep. 2009; 3(1):64-7. View in: PubMed

Preliminary 6 month results from the Argus II epiretinal prosthesis feasibility study. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:4566-8. View in: PubMed

Natural course of experimental retinal vein occlusion in rabbit; arterial occlusion following venous photothrombosis. Graefes Arch Clin Exp Ophthalmol. 2008 Oct; 246(10):1429-39. View in: PubMed

A reversible thermosensitive adhesive for retinal implants: in vivo experience with plasma-deposited poly(N-isopropyl acrylamide). Retina. 2008 Oct; 28(9):1338-43. View in: PubMed

Port geometry and its influence on vitrectomy. Retina. 2008 Oct; 28(8):1061-7. View in: PubMed

A refillable microfabricated drug delivery device for treatment of ocular diseases. Lab Chip. 2008 Jul; 8(7):1027-30. View in: PubMed

Factors affecting perceptual thresholds in epiretinal prostheses. Invest Ophthalmol Vis Sci. 2008 Jun; 49(6):2303-14. View in: PubMed

An in vitro model of a retinal prosthesis. IEEE Trans Biomed Eng. 2008 Jun; 55(6):1744-53. View in: PubMed

The efficacy of retrobulbar block anesthesia only in pars plana vitrectomy and transconjunctival sutureless vitrectomy. Ophthalmic Surg Lasers Imaging. 2008 May-Jun; 39(3):191-5. View in: PubMed

The dependence of spectral impedance on disc microelectrode radius. IEEE Trans Biomed Eng. 2008 Apr; 55(4):1457-60. View in: PubMed

Handheld forward-imaging needle endoscope for ophthalmic optical coherence tomography inspection. J Biomed Opt. 2008 Mar-Apr; 13(2):020505. View in: PubMed

Intravitreal and subretinal injection of tissue plasminogen activator (tPA) in the treatment of experimentally created retinal vein occlusion in rabbits. Retina. 2008 Feb; 28(2):350-5. View in: PubMed

Vitreous dynamics: vitreous flow analysis in 20-, 23-, and 25-gauge cutters. Retina. 2008 Feb; 28(2):236-41. View in: PubMed

Performance analysis of new-generation vitreous cutters. Graefes Arch Clin Exp Ophthalmol. 2008 Jan; 246(1):61-7. View in: PubMed

The effects of intravitreous bevacizumab on retinal neovascular membrane and normal capillaries in rabbits. Invest Ophthalmol Vis Sci. 2007 Dec; 48(12):5708-15. View in: PubMed

Determining the acoustic properties of the lens using a high-frequency ultrasonic needle transducer. Ultrasound Med Biol. 2007 Dec; 33(12):1971-7. View in: PubMed

Evaluation of lens hardness in cataract surgery using high-frequency ultrasonic parameters in vitro. Ultrasound Med Biol. 2007 Oct; 33(10):1609-16. View in: PubMed

Reversible thermosensitive glue for retinal implants. Retina. 2007 Sep; 27(7):938-42. View in: PubMed

Visual performance using a retinal prosthesis in three subjects with retinitis pigmentosa. Am J Ophthalmol. 2007 May; 143(5):820-827. View in: PubMed

Evaluation of a stereoscopic camera-based three-dimensional viewing workstation for ophthalmic surgery. Am J Ophthalmol. 2007 May; 143(5):891-2. View in: PubMed

PMN-PT single crystal, high-frequency ultrasonic needle transducers for pulsed-wave Doppler application. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Mar; 54(3):668-75. View in: PubMed

Real and virtual mobility performance in simulated prosthetic vision. J Neural Eng. 2007 Mar; 4(1):S92-101. View in: PubMed

Electrical properties of retinal-electrode interface. J Neural Eng. 2007 Mar; 4(1):S24-9. View in: PubMed

Snapshot hyperspectral imaging in ophthalmology. J Biomed Opt. 2007 Jan-Feb; 12(1):014036. View in: PubMed

Effect of oxygenated intraocular irrigation solutions on the electroretinogram after vitrectomy. Retina. 2007 Jan; 27(1):87-94. View in: PubMed

A novel method to oxygenate intraocular irrigation fluids with an in-line oxygenator. Retina. 2007 Jan; 27(1):83-6. View in: PubMed

Electrical stimulation in normal and retinal degeneration (rd1) isolated mouse retina. Vision Res. 2006 Oct; 46(19):3198-204. View in: PubMed

Electrical stimulation in isolated rabbit retina. IEEE Trans Neural Syst Rehabil Eng. 2006 Sep; 14(3):290-8. View in: PubMed

Intraocular retinal prosthesis. Big steps to sight restoration. IEEE Eng Med Biol Mag. 2006 Sep-Oct; 25(5):60-6. View in: PubMed

Enucleated eye model for intraocular retinal prosthesis implantation. Ophthalmic Surg Lasers Imaging. 2006 Jul-Aug; 37(4):341-3. View in: PubMed

Nanobiolistic delivery of indicators to the living mouse retina. J Neurosci Methods. 2006 May 15; 153(1):154-61. View in: PubMed

In vitro and in vivo evaluation of ultrananocrystalline diamond for coating of implantable retinal microchips. J Biomed Mater Res B Appl Biomater. 2006 May; 77(2):273-81. View in: PubMed

One-year results of a pilot study using oral 13-cis retinoic acid as a treatment for subfoveal predominantly occult choroidal neovascularization in patients with age-related macular degeneration. Retina. 2006 Mar; 26(3):314-21. View in: PubMed

Paragraph text reading using a pixelized prosthetic vision simulator: parameter dependence and task learning in free-viewing conditions. Invest Ophthalmol Vis Sci. 2006 Mar; 47(3):1241-50. View in: PubMed

Retinal prostheses for the blind. Ann Acad Med Singapore. 2006 Mar; 35(3):137-44. View in: PubMed

Neural responses elicited by electrical stimulation of the retina. Trans Am Ophthalmol Soc. 2006; 104:252-9. View in: PubMed

Implantation of an inactive epiretinal poly(dimethyl siloxane) electrode array in dogs. Exp Eye Res. 2006 Jan; 82(1):81-90. View in: PubMed

A dual band wireless power and data telemetry for retinal prosthesis. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:4392-5. View in: PubMed

A transcutaneous data telemetry system tolerant to power telemetry interference. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:5884-7. View in: PubMed

Old idea, new technology. IEEE Eng Med Biol Mag. 2005 Sep-Oct; 24(5):12-3. View in: PubMed

Rapid recurrence of geographic atrophy after full macular translocation for nonexudative age-related macular degeneration. Ophthalmology. 2005 Sep; 112(9):1586-91. View in: PubMed

A biomimetic retinal stimulating array. IEEE Eng Med Biol Mag. 2005 Sep-Oct; 24(5):14-21. View in: PubMed

Perceptual thresholds and electrode impedance in three retinal prosthesis subjects. IEEE Trans Neural Syst Rehabil Eng. 2005 Jun; 13(2):201-6. View in: PubMed

Outcomes of 140 consecutive cases of 25-gauge transconjunctival surgery for posterior segment disease. Ophthalmology. 2005 May; 112(5):817-24. View in: PubMed

Transvitreal limited arteriovenous-crossing manipulation without vitrectomy for complicated branch retinal vein occlusion using 25-gauge instrumentation. Retina. 2005 Apr-May; 25(3):272-80. View in: PubMed

Long-term stimulation by active epiretinal implants in normal and RCD1 dogs. J Neural Eng. 2005 Mar; 2(1):S65-73. View in: PubMed

Laser-induced changes in intraretinal oxygen distribution in pigmented rabbits. Invest Ophthalmol Vis Sci. 2005 Mar; 46(3):988-99. View in: PubMed

Retinal prosthesis. Annu Rev Biomed Eng. 2005; 7:361-401. View in: PubMed

A wireless phase shift keying transmitter with q-independent phase transition time. Conf Proc IEEE Eng Med Biol Soc. 2005; 5:5238-41. View in: PubMed

A programmable discharge circuitry with current limiting capability for a retinal prosthesis. Conf Proc IEEE Eng Med Biol Soc. 2005; 5:5234-7. View in: PubMed

Progress towards a high-resolution retinal prosthesis. Conf Proc IEEE Eng Med Biol Soc. 2005; 7:7373-5. View in: PubMed

Retinal vein cannulation with prolonged infusion of tissue plasminogen activator (t-PA) for the treatment of experimental retinal vein occlusion in dogs. Am J Ophthalmol. 2004 Nov; 138(5):829-39. View in: PubMed

Retinal thickness in normal and RCD1 dogs using optical coherence tomography. Ophthalmic Surg Lasers Imaging. 2004 Nov-Dec; 35(6):485-93. View in: PubMed

Macular translocation in patients with recurrent subfoveal choroidal neovascularization after laser photocoagulation for nonsubfoveal choroidal neovascularization. Ophthalmology. 2004 Oct; 111(10):1889-93. View in: PubMed

Electrical stimulation of isolated retina with microwire glass electrodes. J Neurosci Methods. 2004 Aug 30; 137(2):265-73. View in: PubMed

Thermal elevation in the human eye and head due to the operation of a retinal prosthesis. IEEE Trans Biomed Eng. 2004 Aug; 51(8):1469-77. View in: PubMed

Comparison of electrical stimulation thresholds in normal and retinal degenerated mouse retina. Jpn J Ophthalmol. 2004 Jul-Aug; 48(4):345-9. View in: PubMed

Use of rotational sutures for limited retinal translocation: a new technique for superior limited macular translocation. Am J Ophthalmol. 2004 May; 137(5):901-7. View in: PubMed

Vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor: implications for ocular angiogenesis. Am J Ophthalmol. 2004 Apr; 137(4):668-74. View in: PubMed

Virtual vitreoretinal surgical simulator as a training tool. Retina. 2004 Apr; 24(2):231-6. View in: PubMed

Retinal pigment epithelial abnormalities after internal limiting membrane peeling guided by indocyanine green staining. Retina. 2004 Feb; 24(1):157-60. View in: PubMed

Effects of intravitreal indocyanine green injection in rabbits. Retina. 2004 Feb; 24(1):69-79. View in: PubMed

Effects of indocyanine green injection on the retinal surface and into the subretinal space in rabbits. Retina. 2004 Feb; 24(1):80-91. View in: PubMed

Intraocular impedance as a function of the position in the eye, electrode material and electrode size. Conf Proc IEEE Eng Med Biol Soc. 2004; 6:4169-71. View in: PubMed

DSP based image processing for retinal prosthesis. Conf Proc IEEE Eng Med Biol Soc. 2004; 2:1475-8. View in: PubMed

A test microchip for evaluation of hermetic packaging technology for biomedical prosthetic implants. Conf Proc IEEE Eng Med Biol Soc. 2004; 6:4093-5. View in: PubMed

Characteristics of visual loss by scanning laser ophthalmoscope microperimetry in eyes with subfoveal choroidal neovascularization secondary to age-related macular degeneration. Am J Ophthalmol. 2003 Dec; 136(6):1067-78. View in: PubMed

Facial recognition using simulated prosthetic pixelized vision. Invest Ophthalmol Vis Sci. 2003 Nov; 44(11):5035-42. View in: PubMed

Visually guided performance of simple tasks using simulated prosthetic vision. Artif Organs. 2003 Nov; 27(11):1016-28. View in: PubMed

Visual perception in a blind subject with a chronic microelectronic retinal prosthesis. Vision Res. 2003 Nov; 43(24):2573-81. View in: PubMed

Past, present, and future of artificial vision. Artif Organs. 2003 Nov; 27(11):961-2. View in: PubMed

Bilateral neuroretinopathy with multiple retinal arterial aneurysms. Arch Ophthalmol. 2003 Aug; 121(8):1206-7. View in: PubMed

Advances in the development of visual prostheses. Curr Opin Ophthalmol. 2003 Jun; 14(3):122-7. View in: PubMed

Angiographic characteristics in patients undergoing macular translocation for subfoveal choroidal neovascularization secondary to age-related macular degeneration. Retina. 2003 Apr; 23(2):152-8. View in: PubMed

Visual and electrical evoked response recorded from subdural electrodes implanted above the visual cortex in normal dogs under two methods of anesthesia. J Neurosci Methods. 2003 Mar 15; 123(2):129-37. View in: PubMed

Heat effects on the retina. Ophthalmic Surg Lasers Imaging. 2003 Mar-Apr; 34(2):114-20. View in: PubMed

Limited macular translocation for the management of subfoveal choroidal neovascularization after photodynamic therapy. Am J Ophthalmol. 2003 Jan; 135(1):109-12. View in: PubMed

Improvements after sheathotomy for branch retinal vein occlusion documented by optical coherence tomography and scanning laser ophthalmoscope. Ophthalmic Surg Lasers Imaging. 2003 Jan-Feb; 34(1):49-52. View in: PubMed

The value of preoperative tests in the selection of blind patients for a permanent microelectronic implant. Trans Am Ophthalmol Soc. 2003; 101:223-8; discussion 228-30. View in: PubMed

Limited macular translocation: current concepts. Ophthalmol Clin North Am. 2002 Dec; 15(4):425-36. View in: PubMed

In vitro electrical properties for iridium oxide versus titanium nitride stimulating electrodes. IEEE Trans Biomed Eng. 2002 Dec; 49(12 Pt 2):1574-9. View in: PubMed

Initial experience using the transconjunctival sutureless vitrectomy system for vitreoretinal surgery. Ophthalmology. 2002 Oct; 109(10):1814-20. View in: PubMed

A new 25-gauge instrument system for transconjunctival sutureless vitrectomy surgery. Ophthalmology. 2002 Oct; 109(10):1807-12; discussion 1813. View in: PubMed

Increased spontaneous retinal ganglion cell activity in rd mice after neural retinal transplantation. Invest Ophthalmol Vis Sci. 2002 Sep; 43(9):3053-8. View in: PubMed

Patient selection for macular translocation surgery using the scanning laser ophthalmoscope. Ophthalmology. 2002 Sep; 109(9):1737-44. View in: PubMed

Inferior limited macular translocation for subfoveal choroidal neovascularization secondary to age-related macular degeneration: 1-year visual outcome and recurrence report. Am J Ophthalmol. 2002 Jul; 134(1):69-74. View in: PubMed

Retinal prosthesis for the blind. Surv Ophthalmol. 2002 Jul-Aug; 47(4):335-56. View in: PubMed

Ganglion cell responses to retinal light stimulation in the absence of photoreceptor outer segments from retinal degenerate rodents. Curr Eye Res. 2002 Jan; 24(1):26-32. View in: PubMed

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