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Mary Samplaski, MD
Assistant Professor of Clinical Urology
NOR 1441 Eastlake Ave Health Sciences Campus Los Angeles
+1 323 865 3700


Dr. Samplaski is a specialist in in Male Reproductive Medicine, Microsurgery and Andrology. She completed her medical school at the George Washington University School of Medicine, urology residency at the Cleveland Clinic, and specialty fellowship at the University of Toronto. Dr. Samplaski is an expert in all aspects of male reproductive health, including fertility preservation counseling and treatment, vasectomies and vasectomy reversals, low testosterone, erectile dysfunction, sexual dysfunction, Peyronie’s disease and testicular pain. She specializes in the management of male infertility with the aim of improving natural conception or improved outcomes from assisted reproduction. She also specializes in fertility for spinal cord injury patients. Surgical techniques that she is skilled in for the treatment of these conditions include the minimally invasive vasectomy and microsurgical vasectomy reversals, advanced sperm retrieval techniques, microscopic varicocele repair, penile vibratory stimulation, electroejaculation and spermatic cord denervations. For erectile dysfunction she also specializes in correction of penile curvature and penile prostheses for erectile dysfunction. Dr. Samplaski has a strong record demonstrating a commitment to educational excellence and advancing the field of male fertility. She consistently presents at major national and international meetings and is a reviewer for several scientific journals. At present, the cause of 60% of male factor infertility is completely unknown. She believes that this represents a major opportunity for scientific advancement in order to make parenthood possible for everyone desiring it.


Urinary mycobacterium avium presenting as sterile pyuria. Can Urol Assoc J. 2016 May-Jun; 10(5-6):E186-E188. View in: PubMed

Prognostic factors for a favorable outcome after varicocele repair in adolescents and adults. Asian J Androl. 2016 Mar-Apr; 18(2):217-21. View in: PubMed

Anatomical Targeting Improves Delivery of Unconjugated Nanoparticles to the Testicle. J Urol. 2015 Oct; 194(4):1155-61. View in: PubMed

Human Fetal Testicular Tissue Xenotransplantation: A Platform to Study the Effect of Gonadotropins on Human Germ Cell Development In Utero. J Urol. 2015 Aug; 194(2):585-91. View in: PubMed

Adverse effects of common medications on male fertility. Nat Rev Urol. 2015 Jul; 12(7):401-13. View in: PubMed

Cocaine Use in the Infertile Male Population: A Marker for Conditions Resulting in Subfertility. Curr Urol. 2015 May; 8(1):38-42. View in: PubMed

The relationship between sperm viability and DNA fragmentation rates. Reprod Biol Endocrinol. 2015; 13(1):42. View in: PubMed

Nomograms for predicting changes in semen parameters in infertile men after varicocele repair. Fertil Steril. 2014 Jul; 102(1):68-74. View in: PubMed

Editorial comment. J Urol. 2014 May; 191(5):1415. View in: PubMed

Phenotypic differences in mosaic Klinefelter patients as compared with non-mosaic Klinefelter patients. Fertil Steril. 2014 Apr; 101(4):950-5. View in: PubMed

Genetic and Epigenetic Changes After Spermatogonial Stem Cell Culture and Transplantation. EJIFCC. 2014 Apr; 25(1):27-41. View in: PubMed

Vasectomy as a reversible form of contraception for select patients. Can J Urol. 2014 Apr; 21(2):7234-40. View in: PubMed

Superoxide dismutase-loaded biodegradable nanoparticles targeted with a follicle-stimulating hormone peptide protect Sertoli cells from oxidative stress. Fertil Steril. 2014 Feb; 101(2):560-567. e3. View in: PubMed

Testosterone use in the male infertility population: prescribing patterns and effects on semen and hormonal parameters. Fertil Steril. 2014 Jan; 101(1):64-9. View in: PubMed

Finasteride use in the male infertility population: effects on semen and hormone parameters. Fertil Steril. 2013 Dec; 100(6):1542-6. View in: PubMed

Clustering of UPOINT domains and subdomains in men with chronic prostatitis/chronic pelvic pain syndrome and contribution to symptom severity. J Urol. 2012 Nov; 188(5):1788-93. View in: PubMed

Folate hydrolase (prostate-specific membrane [corrected] antigen) 1 expression in bladder cancer subtypes and associated tumor neovasculature. Mod Pathol. 2011 Nov; 24(11):1521-9. View in: PubMed

Drug delivery to the testis: current status and potential pathways for the development of novel therapeutics. Drug Deliv Transl Res. 2011 Oct; 1(5):351-60. View in: PubMed

Inclusion of erectile domain to UPOINT phenotype does not improve correlation with symptom severity in men with chronic prostatitis/chronic pelvic pain syndrome. Urology. 2011 Sep; 78(3):653-8. View in: PubMed

Functional and quality-of-life outcomes in patients undergoing transperineal repair with gracilis muscle interposition for complex rectourethral fistula. Urology. 2011 Mar; 77(3):736-41. View in: PubMed

Renal mass sampling: an enlightened perspective. Int J Urol. 2011 Jan; 18(1):5-19. View in: PubMed

C-index is associated with functional outcomes after laparoscopic partial nephrectomy. J Urol. 2010 Dec; 184(6):2259-63. View in: PubMed

New generation of diagnostic tests for infertility: review of specialized semen tests. Int J Urol. 2010 Oct; 17(10):839-47. View in: PubMed

Kidney tumor location measurement using the C index method. J Urol. 2010 May; 183(5):1708-13. View in: PubMed

Post-transplantation lymphoproliferative disorder in the renal transplant ureter. Urology. 2010 Mar; 75(3):516-9. View in: PubMed

Less-invasive ways to remove stones from the kidneys and ureters. Cleve Clin J Med. 2009 Oct; 76(10):592-8. View in: PubMed

Apocrine hidrocystoma on glans penis of a child. Urology. 2009 Apr; 73(4):800-1. View in: PubMed

Two centuries of cystoscopy: the development of imaging, instrumentation and synergistic technologies. BJU Int. 2009 Jan; 103(2):154-8. View in: PubMed

Malignant melanoma of the gallbladder: a report of two cases and review of the literature. J Gastrointest Surg. 2008 Jun; 12(6):1123-6. View in: PubMed

Renal mass biopsy--a renaissance? J Urol. Renal mass biopsy--a renaissance? J Urol. 2008 Jan; 179(1):20-7. View in: PubMed

Time course of neuroanatomical and functional recovery after bilateral pudendal nerve injury in female rats. Am J Physiol Renal Physiol. 2007 Nov; 293(5):F1614-21. View in: PubMed

Activation of human eosinophils through leukocyte immunoglobulin-like receptor 7. Proc Natl Acad Sci U S A. 2003 Feb 4; 100(3):1174-9. View in: PubMed

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