Faculty

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Omid Akbari, PhD
Professor of Molecular Microbiology & Immunology
Molecular Microbiology and Immunology
NRT 5505 1450 Biggy Street Health Sciences Campus Los Angeles
+1 323 442 7930

Publications

Reply. J Allergy Clin Immunol. 2016 Nov 12. View in: PubMed

Nicotinic acetylcholine receptor agonist attenuates ILC2-dependent airway hyperreactivity. Nat Commun. 2016 Oct 18; 7:13202. View in: PubMed

Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuronal protein ELAVL4. J Neuroimmunol. 2016 Oct 15; 299:70-78. View in: PubMed

Innate lymphoid cells: a paradigm for low SSI in cleft lip repair. J Surg Res. 2016 Oct; 205(2):312-7. View in: PubMed

I?B Kinase e Is an NFATc1 Kinase that Inhibits T Cell Immune Response. Cell Rep. 2016 Jul 12; 16(2):405-18. View in: PubMed

Lower omental t-regulatory cell count is associated with higher fasting glucose and lower ß-cell function in adults with obesity. Obesity (Silver Spring). 2016 Jun; 24(6):1274-82. View in: PubMed

Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission. Immunity. 2016 May 17; 44(5):1204-14. View in: PubMed

Impact of Hepatitis C Virus on the Circulating Levels of IL-7 in HIV-1 Coinfected Women. J Acquir Immune Defic Syndr. 2016 Feb 1; 71(2):172-80. View in: PubMed

Lack of autophagy induces steroid-resistant airway inflammation. J Allergy Clin Immunol. 2015 Nov 14. View in: PubMed

ICOS regulates ILC2s in asthma. Oncotarget. 2015 Aug 22. View in: PubMed

A Subset of CD8aß+ Invariant NKT Cells in a Humanized Mouse Model. J Immunol. 2015 Aug 15; 195(4):1459-69. View in: PubMed

ICOS:ICOS-Ligand Interaction Is Required for Type 2 Innate Lymphoid Cell Function, Homeostasis, and Induction of Airway Hyperreactivity. Immunity. 2015 Mar 17; 42(3):538-51. View in: PubMed

Batf3 deficiency is not critical for the generation of CD8a(+) dendritic cells. Immunobiology. 2014 Oct 30. View in: PubMed

Inclusion of CD80 in HSV Targets the Recombinant Virus to PD-L1 on DCs and Allows Productive Infection and Robust Immune Responses. PLoS One. 2014; 9(1):e87617. View in: PubMed

Programmed cell death ligand 2 regulates TH9 differentiation and induction of chronic airway hyperreactivity. J Allergy Clin Immunol. 2013 Apr; 131(4):1048-57, 1057. e1-2. View in: PubMed

Sex-specific perinatal nicotine-induced asthma in rat offspring. Am J Respir Cell Mol Biol. 2013 Jan; 48(1):53-62. View in: PubMed

Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection. PLoS One. 2013; 8(3):e59599. View in: PubMed

Structural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties. J Immunol. 2012 Mar 1; 188(5):2254-65. View in: PubMed

Effects of Systemic versus Local Administration of Corticosteroids on Mucosal Tolerance. J Immunol. 2012 Jan 1; 188(1):470-6. View in: PubMed

Perinatal nicotine exposure induces asthma in second generation offspring. BMC Med. 2012; 10:129. View in: PubMed

Epithelium-specific deletion of TGF-ß receptor type II protects mice from bleomycin-induced pulmonary fibrosis. J Clin Invest. 2011 Jan 4; 121(1):277-87. View in: PubMed

TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells. J Immunol. 2010 Dec 1; 185(11):6839-49. View in: PubMed

A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity. J Immunol. 2010 Feb 15; 184(4):2107-15. View in: PubMed

PD-L1 and PD-L2 modulate airway inflammation and iNKT-cell-dependent airway hyperreactivity in opposing directions. Mucosal Immunol. 2010 Jan; 3(1):81-91. View in: PubMed

The role of costimulatory molecules in allergic disease and asthma. Int Arch Allergy Immunol. 2010; 151(3):179-89. View in: PubMed

Dendritic cell modulation as a new interventional approach for the treatment of asthma. Drug News Perspect. 2009 Oct; 22(8):445-51. View in: PubMed

Natural killer T cells in the lungs of patients with asthma. J Allergy Clin Immunol. 2009 May; 123(5):1181-5. View in: PubMed

Induction of airway hyperreactivity by IL-25 is dependent on a subset of invariant NKT cells expressing IL-17RB. J Immunol. 2009 Apr 15; 182(8):5116-22. View in: PubMed

Activation of nonclassical CD1d-restricted NK T cells induces airway hyperreactivity in beta 2-microglobulin-deficient mice. J Immunol. 2008 Oct 1; 181(7):4560-9. View in: PubMed

Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR alpha-chain CDR3 loop. Eur J Immunol. 2008 Jun; 38(6):1756-66. View in: PubMed

ICOS/ICOSL interaction is required for CD4+ invariant NKT cell function and homeostatic survival. J Immunol. 2008 Apr 15; 180(8):5448-56. View in: PubMed

Recent advances in the role of NKT cells in allergic diseases and asthma. Curr Allergy Asthma Rep. 2008 Apr; 8(2):165-70. View in: PubMed

Invariant natural killer T cells in obstructive pulmonary diseases. N Engl J Med. 2007 Jul 12; 357(2):193-4; author reply 194-5. View in: PubMed

CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma. N Engl J Med. 2006 Mar 16; 354(11):1117-29. View in: PubMed

Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2782-7. View in: PubMed

Respiratory tolerance is inhibited by the administration of corticosteroids. J Immunol. 2005 Dec 1; 175(11):7380-7. View in: PubMed

TIM-1 induces T cell activation and inhibits the development of peripheral tolerance. Nat Immunol. 2005 May; 6(5):447-54. View in: PubMed

Role of regulatory dendritic cells in allergy and asthma. Curr Allergy Asthma Rep. 2005 Jan; 5(1):56-61. View in: PubMed

Role of regulatory dendritic cells in allergy and asthma. Curr Opin Allergy Clin Immunol. 2004 Dec; 4(6):533-8. View in: PubMed

Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity. Nat Immunol. 2004 Nov; 5(11):1149-56. View in: PubMed

CD8(+) T cells regulate immune responses in a murine model of allergen-induced sensitization and airway inflammation. Eur J Immunol. 2004 Jul; 34(7):1817-27. View in: PubMed

Role of regulatory T cells in allergy and asthma. Curr Opin Immunol. 2003 Dec; 15(6):627-33. View in: PubMed

Regulatory T cells control the development of allergic disease and asthma. J Allergy Clin Immunol. 2003 Sep; 112(3):480-7; quiz 488. View in: PubMed

Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nat Med. 2003 May; 9(5):582-8. View in: PubMed

Mucosal tolerance and immunity: regulating the development of allergic disease and asthma. Int Arch Adlergy Immunol. 2003 Feb; 130(2)2108-18. 4/prns:informatignResourceReferefce>. View in: PubMed

Mucosal tolerance and immunity: regulating the development of allergic disease and asthma. Int Arch Allergy Immunol. 2003 Feb; 130(2):108-18. View in: PubMed

CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation. J Allergy Clin Immunol. 2002 Sep; 110(3):460-8. View in: PubMed

Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med. 2002 Sep; 8(9):1024-32. View in: PubMed

Asthma: an epidemic of dysregulated immunity. Nat Immunol. 2002 Aug; 3(8):715-20. View in: PubMed

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