Faculty

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Paul M. Thompson, PhD
Professor of Ophthalmology
Associate Director, USC Mark and Mary Stevens Neuroimaging and Informatics Institute
USC Institute for Neuroimaging and Informatics
STT 2001 N. SOTO Street Health Sciences Campus Los Angeles
+1 323 442 7246

Overview

Paul Thompson is a Professor in the Keck School of Medicine of USC. His team's research projects focus on the neuroscience, mathematics, computer science, software engineering and clinical aspects of neuroimaging and brain mapping.

Paul Thompson directs the ENIGMA Consortium, a global alliance of 307 scientists in 33 countries who conduct the largest studies of 10 major brain diseases – ranging from schizophrenia, depression, ADHD, bipolar illness and OCD, to HIV and addictions on the brain. ENIGMA’s genomic screens of over 31,000 people’s brain scans and genome-wide data (published in Nature Genetics, 2012; Nature, 2015) have brought together experts from 185 institutions to unearth genetic variants that affect brain structure, disease risk, and brain connectivity. At USC, Dr. Thompson is a Professor of Neurology, Psychiatry, Radiology, Pediatrics, Engineering, and Ophthalmology, and Director of the ENIGMA Center for Worldwide Medicine, Imaging & Genomics - a $11M NIH Center of Excellence in Big Data Computing. Using worldwide medication screens, ENIGMA discovers factors that affect progression of Alzheimer’s disease and other dementias, schizophrenia, depression and childhood brain
disorders. One study unites teams from the Thai Red Cross, the US, and South Africa, and uses methods developed by Dr Thompson’s team (Nature, 2000) to study how treatments restore brain growth in HIV+ children. Dr. Thompson also directs the USC Imaging Genetics Center– a group of 40 scientists in Marina del Rey. His team created the first maps of Alzheimer’s disease and schizophrenia spreading in the living brain, and a method to track brain growth in children. Dr. Thompson has an M.A. in mathematics and Greek and Latin Languages from Oxford University, and a PhD in neuroscience from UCLA.

Collaborating with imaging labs around the world, Dr. Thompson and his students have published over 1,300 publications (h-index: 116) describing novel mathematical and computational strategies for analyzing brain image databases, for detecting pathology in individual patients and groups, and for creating disease-specific atlases of the human brain.

Recent work has discovered new structural and functional brain changes during brain development and degeneration, Alzheimer's Disease and other dementias, schizophrenia and bipolar illness, HIV/AIDS, methamphetamine abuse, and autism. For many of these illnesses, Dr. Thompson's Center is creating population-based tools to understand factors that resist them. New computational tools, developed in the lab, are used to map how these diseases spread in the living brain, and in drug trials and basic research studies.

Awards

Di Chiro Outstanding Scientific Paper Award

Eiduson Award for Neuroscience Research

Outstanding Graduate Student of the Year, UCLA, UCLA Chancellor's Service Award

SPIE Medical Imaging Award, Best Paper

Kent Innovations in Academia Award

Publications

Wade BS, Joshi SH, Njau S, Leaver AM, Vasavada M, Woods RP, Gutman BA, Thompson PM, Espinoza R, Narr KL. Effect of Electroconvulsive Therapy on Striatal Morphometry in Major Depressive Disorder. Neuropsychopharmacology. 2016 Sep; 41(10):2481-91. View in: PubMed

Roussotte FF, Narr KL, Small GW, Thompson PM. The C677T variant in MTHFR modulates associations between blood-based and cerebrospinal fluid biomarkers of neurodegeneration. Neuroreport. 2016 Aug 17; 27(12):948-51. View in: PubMed

Roussotte FF, Narr KL, Small GW, Thompson PM. The C677T variant in MTHFR modulates associations between blood-based and cerebrospinal fluid biomarkers of neurodegeneration. Neuroreport. 2016 Aug 17; 27(12):948-51. View in: PubMed

Riedel BC, Thompson PM, Brinton RD. Age, APOE and sex: Triad of risk of Alzheimer's disease. J Steroid Biochem Mol Biol. 2016 Jun; 160:134-47. View in: PubMed

Shen KK, Doré V, Rose S, Fripp J, McMahon KL, de Zubicaray GI, Martin NG, Thompson PM, Wright MJ, Salvado O. Heritability and genetic correlation between the cerebral cortex and associated white matter connections. Hum Brain Mapp. 2016 Jun; 37(6):2331-47. View in: PubMed

Dennis EL, Hua X, Villalon-Reina J, Moran LM, Kernan C, Babikian T, Mink R, Babbitt C, Johnson J, Giza CC, Thompson PM, Asarnow RF. Tensor-Based Morphometry Reveals Volumetric Deficits in Moderate=Severe Pediatric Traumatic Brain Injury. J Neurotrauma. 2016 May 1; 33(9):840-52. View in: PubMed

Becker M, Guadalupe T, Franke B, Hibar DP, Renteria ME, Stein JL, Thompson PM, Francks C, Vernes SC, Fisher SE. Early developmental gene enhancers affect subcortical volumes in the adult human brain. Hum Brain Mapp. 2016 May; 37(5):1788-800. View in: PubMed

Lupton MK, Strike L, Hansell NK, Wen W, Mather KA, Armstrong NJ, Thalamuthu A, McMahon KL, de Zubicaray GI, Assareh AA, Simmons A, Proitsi P, Powell JF, Montgomery GW, Hibar DP, Westman E, Tsolaki M, Kloszewska I, Soininen H, Mecocci P, Velas B, Lovestone S. The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume. Neurobiol Aging. 2016 Apr; 40:68-77. View in: PubMed

Raji CA, Merrill DA, Eyre H, Mallam S, Torosyan N, Erickson KI, Lopez OL, Becker JT, Carmichael OT, Gach HM, Thompson PM, Longstreth WT, Kuller LH. Longitudinal Relationships between Caloric Expenditure and Gray Matter in the Cardiovascular Health Study. J Alzheimers Dis. 2016 Mar 11; 52(2):719-29. View in: PubMed

Whelan CD, Hibar DP, van Velzen LS, Zannas AS, Carrillo-Roa T, McMahon K, Prasad G, Kelly S, Faskowitz J, deZubiracay G, Iglesias JE, van Erp TG, Frodl T, Martin NG, Wright MJ, Jahanshad N, Schmaal L, Sämann PG, Thompson PM. Heritability and reliability of automatically segmented human hippocampal formation subregions. Neuroimage. 2016 Mar; 128:125-37. View in: PubMed

Franke B, Stein JL, Ripke S, Anttila V, Hibar DP, van Hulzen KJ, Arias-Vasquez A, Smoller JW, Nichols TE, Neale MC, McIntosh AM, Lee P, McMahon FJ, Meyer-Lindenberg A, Mattheisen M, Andreassen OA, Gruber O, Sachdev PS, Roiz-Santiañez R, Saykin AJ, Ehrlich S, Mather KA, Turner JA, Schwarz E, Thalamuthu A, Yao Y, Ho YY, Martin NG, Wright MJ. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nat Neurosci. 2016 Mar; 19(3):420-31. View in: PubMed

Daianu M, Mezher A, Mendez MF, Jahanshad N, Jimenez EE, Thompson PM. Disrupted rich club network in behavioral variant frontotemporal dementia and early-onset Alzheimer's disease. Hum Brain Mapp. 2016 Mar; 37(3):868-83. View in: PubMed

Kochunov P, Fu M, Nugent K, Wright SN, Du X, Muellerklein F, Morrissey M, Eskandar G, Shukla DK, Jahanshad N, Thompson PM, Patel B, Postolache TT, Strauss KA, Shuldiner AR, Mitchell BD, Hong LE. Heritability of complex white matter diffusion traits assessed in a population isolate. Hum Brain Mapp. 2016 Feb; 37(2):525-35. View in: PubMed

Kochunov P, Thompson PM, Winkler A, Morrissey M, Fu M, Coyle TR, Du X, Muellerklein F, Savransky A, Gaudiot C, Sampath H, Eskandar G, Jahanshad N, Patel B, Rowland L, Nichols TE, O'Connell JR, Shuldiner AR, Mitchell BD, Hong LE. The common genetic influence over processing speed and white matter microstructure: Evidence from the Old Order Amish and Human Connectome Projects. Neuroimage. 2016 Jan 15; 125:189-97. View in: PubMed

Hua X, Ching CR, Mezher A, Gutman BA, Hibar DP, Bhatt P, Leow AD, Jack CR, Bernstein MA, Weiner MW, Thompson PM. MRI-based brain atrophy rates in ADNI phase 2: acceleration and enrichment considerations for clinical trials. Neurobiol Aging. 2016 Jan; 37:26-37. View in: PubMed

Shan ZY, Vinkhuyzen AA, Thompson PM, McMahon KL, Blokland GA, de Zubicaray GI, Calhoun V, Martin NG, Visscher PM, Wright MJ, Reutens DC. Genes influence the amplitude and timing of brain hemodynamic responses. Neuroimage. 2016 Jan 1; 124(Pt A):663-71. View in: PubMed

Li B, Shi J, Gutman BA, Baxter LC, Thompson PM, Caselli RJ, Wang Y. Influence of APOE Genotype on Hippocampal Atrophy over Time - An N=1925 Surface-Based ADNI Study. PLoS One. 2016; 11(4):e0152901. View in: PubMed

Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, McDade E, Ringman JM, Thompson PM, Saykin AJ, Ghetti B, Sperling RA, Johnson KA, Salloway SP, Schofield PR, Masters CL, Villemagne VL, Fox NC, Förster S, Chen K, Reiman EM, Xiong C, Marcus DS, Weiner MW, Morris JC, Bateman RJ, Benzinger TL. Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. PLoS One. 2016; 11(3):e0152082. View in: PubMed

Mackey S, Kan KJ, Chaarani B, Alia-Klein N, Batalla A, Brooks S, Cousijn J, Dagher A, de Ruiter M, Desrivieres S, Feldstein Ewing SW, Goldstein RZ, Goudriaan AE, Heitzeg MM, Hutchison K, Li CS, London ED, Lorenzetti V, Luijten M, Martin-Santos R, Morales AM, Paulus MP, Paus T, Pearlson G, Schluter R, Momenan R, Schmaal L, Schumann G, Sinha R, Sjoerds Z, Stein DJ, Stein EA, Solowij N, Tapert S, Uhlmann A, Veltman D, van Holst R, Walter H, Wright MJ, Yucel M, Yurgelun-Todd D, Hibar DP, Jahanshad N, Thompson PM, Glahn DC, Garavan H, Conrod P. Genetic imaging consortium for addiction medicine: From neuroimaging to genes. Prog Brain Res. 2016; 224:203-23. View in: PubMed

Couvy-Duchesne B, Ebejer JL, Gillespie NA, Duffy DL, Hickie IB, Thompson PM, Martin NG, de Zubicaray GI, McMahon KL, Medland SE, Wright MJ. Head Motion and Inattention/Hyperactivity Share Common Genetic Influences: Implications for fMRI Studies of ADHD. PLoS One. 2016; 11(1):e0146271. View in: PubMed

Thompson PM. Cracking the brain's genetic code. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):15269-70. View in: PubMed

Foland-Ross LC, Sacchet MD, Prasad G, Gilbert B, Thompson PM, Gotlib IH. Cortical thickness predicts the first onset of major depression in adolescence. Int J Dev Neurosci. 2015 Nov; 46:125-31. View in: PubMed

Sinclair B, Hansell NK, Blokland GA, Martin NG, Thompson PM, Breakspear M, de Zubicaray GI, Wright MJ, McMahon KL. Heritability of the network architecture of intrinsic brain functional connectivity. Neuroimage. 2015 Nov 1; 121:243-52. View in: PubMed

Moon SW, Dinov ID, Kim J, Zamanyan A, Hobel S, Thompson PM, Toga AW. Structural Neuroimaging Genetics Interactions in Alzheimer's Disease. J Alzheimers Dis. 2015 Oct 27; 48(4):1051-63. View in: PubMed

Roussotte FF, Gutman BA, Hibar DP, Madsen SK, Narr KL, Thompson PM. Carriers of a common variant in the dopamine transporter gene have greater dementia risk, cognitive decline, and faster ventricular expansion. Alzheimers Dement. 2015 Oct; 11(10):1153-62. View in: PubMed

Jahanshad N, Couture MC, Prasitsuebsai W, Nir TM, Aurpibul L, Thompson PM, Pruksakaew K, Lerdlum S, Visrutaratna P, Catella S, Desai A, Kerr SJ, Puthanakit T, Paul R, Ananworanich J, Valcour VG. Brain Imaging and Neurodevelopment in HIV-uninfected Thai Children Born to HIV-infected Mothers. Pediatr Infect Dis J. 2015 Sep; 34(9):e211-6. View in: PubMed

Bulayeva K, Lesch KP, Bulayev O, Walsh C, Glatt S, Gurgenova F, Omarova J, Berdichevets I, Thompson PM. Genomic structural variants are linked with intellectual disability. J Neural Transm. 2015 Sep; 122(9):1289-301. View in: PubMed

Moon SW, Dinov ID, Hobel S, Zamanyan A, Choi YC, Shi R, Thompson PM, Toga AW. Structural Brain Changes in Early-Onset Alzheimer's Disease Subjects Using the LONI Pipeline Environment. J Neuroimaging. 2015 Sep; 25(5):728-37. View in: PubMed

Martínez K, Madsen SK, Joshi AA, Joshi SH, Román FJ, Villalon-Reina J, Burgaleta M, Karama S, Janssen J, Marinetto E, Desco M, Thompson PM, Colom R. Reproducibility of brain-cognition relationships using three cortical surface-based protocols: An exhaustive analysis based on cortical thickness. Hum Brain Mapp. 2015 Aug; 36(8):3227-45. View in: PubMed

Daianu M, Jahanshad N, Nir TM, Jack CR, Weiner MW, Bernstein MA, Thompson PM. Rich club analysis in the Alzheimer's disease connectome reveals a relatively undisturbed structural core network. Hum Brain Mapp. 2015 Aug; 36(8):3087-103. View in: PubMed

Dennis EL, Ellis MU, Marion SD, Jin Y, Moran L, Olsen A, Kernan C, Babikian T, Mink R, Babbitt C, Johnson J, Giza CC, Thompson PM, Asarnow RF. Callosal Function in Pediatric Traumatic Brain Injury Linked to Disrupted White Matter Integrity. J Neurosci. 2015 Jul 15; 35(28):10202-11. View in: PubMed

Jack CR, Barnes J, Bernstein MA, Borowski BJ, Brewer J, Clegg S, Dale AM, Carmichael O, Ching C, DeCarli C, Desikan RS, Fennema-Notestine C, Fjell AM, Fletcher E, Fox NC, Gunter J, Gutman BA, Holland D, Hua X, Insel P, Kantarci K, Killiany RJ, Krueger G, Leung KK, Mackin S, Maillard P, Malone IB, Mattsson N, McEvoy L, Modat M, Mueller S, Nosheny R, Ourselin S, Schuff N, Senjem ML, Simonson A, Thompson PM, Rettmann D, Vemuri P, Walhovd K, Zhao Y, Zuk S, Weiner M. Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2. Alzheimers Dement. 2015 Jul; 11(7):740-56. View in: PubMed

Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Cedarbaum J, Donohue MC, Green RC, Harvey D, Jack CR, Jagust W, Morris JC, Petersen RC, Saykin AJ, Shaw L, Thompson PM, Toga AW, Trojanowski JQ. Impact of the Alzheimer's Disease Neuroimaging Initiative, 2004 to 2014. Alzheimers Dement. 2015 Jul; 11(7):865-84. View in: PubMed

Saykin AJ, Shen L, Yao X, Kim S, Nho K, Risacher SL, Ramanan VK, Foroud TM, Faber KM, Sarwar N, Munsie LM, Hu X, Soares HD, Potkin SG, Thompson PM, Kauwe JS, Kaddurah-Daouk R, Green RC, Toga AW, Weiner MW. Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans. Alzheimers Dement. 2015 Jul; 11(7):792-814. View in: PubMed

Fears SC, Schür R, Sjouwerman R, Service SK, Araya C, Araya X, Bejarano J, Knowles E, Gomez-Makhinson J, Lopez MC, Aldana I, Teshiba TM, Abaryan Z, Al-Sharif NB, Navarro L, Tishler TA, Altshuler L, Bartzokis G, Escobar JI, Glahn DC, Thompson PM, Lopez-Jaramillo C, Macaya G, Molina J, Reus VI, Sabatti C, Cantor RM, Freimer NB, Bearden CE. Brain structure-function associations in multi-generational families genetically enriched for bipolar disorder. Brain. 2015 Jul; 138(Pt 7):2087-102. View in: PubMed

Roussotte FF, Jahanshad N, Hibar DP, Thompson PM. Altered regional brain volumes in elderly carriers of a risk variant for drug abuse in the dopamine D2 receptor gene (DRD2). Brain Imaging Behav. 2015 Jun; 9(2):213-22. View in: PubMed

Vemuri P, Senjem ML, Gunter JL, Lundt ES, Tosakulwong N, Weigand SD, Borowski BJ, Bernstein MA, Zuk SM, Lowe VJ, Knopman DS, Petersen RC, Fox NC, Thompson PM, Weiner MW, Jack CR. Accelerated vs. unaccelerated serial MRI based TBM-SyN measurements for clinical trials in Alzheimer's disease. Neuroimage. 2015 Jun; 113:61-9. View in: PubMed

Thompson PM, Jahanshad N. Novel Neuroimaging Methods to Understand How HIV Affects the Brain. Curr HIV/AIDS Rep. 2015 Jun; 12(2):289-98. View in: PubMed

Zeifman LE, Eddy WF, Lopez OL, Kuller LH, Raji C, Thompson PM, Becker JT. Voxel Level Survival Analysis of Grey Matter Volume and Incident Mild Cognitive Impairment or Alzheimer's Disease. J Alzheimers Dis. 2015 May 7; 46(1):167-78. View in: PubMed

Kochunov P, Jahanshad N, Marcus D, Winkler A, Sprooten E, Nichols TE, Wright SN, Hong LE, Patel B, Behrens T, Jbabdi S, Andersson J, Lenglet C, Yacoub E, Moeller S, Auerbach E, Ugurbil K, Sotiropoulos SN, Brouwer RM, Landman B, Lemaitre H, den Braber A, Zwiers MP, Ritchie S, van Hulzen K, Almasy L, Curran J, deZubicaray GI, Duggirala R, Fox P, Martin NG, McMahon KL, Mitchell B, Olvera RL, Peterson C, Starr J, Sussmann J, Wardlaw J, Wright M, Boomsma DI, Kahn R, de Geus EJ, Williamson DE, Hariri A, van 't Ent D, Bastin ME, McIntosh A, Deary IJ, Hulshoff Pol HE, Blangero J, Thompson PM, Glahn DC, Van Essen DC. Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data. Neuroimage. 2015 May 1; 111:300-11. View in: PubMed

Woo MA, Ogren JA, Abouzeid CM, Macey PM, Sairafian KG, Saharan PS, Thompson PM, Fonarow GC, Hamilton MA, Harper RM, Kumar R. Regional hippocampal damage in heart failure. Eur J Heart Fail. 2015 May; 17(5):494-500. View in: PubMed

Chalavi S, Vissia EM, Giesen ME, Nijenhuis ER, Draijer N, Cole JH, Dazzan P, Pariante CM, Madsen SK, Rajagopalan P, Thompson PM, Toga AW, Veltman DJ, Reinders AA. Abnormal hippocampal morphology in dissociative identity disorder and post-traumatic stress disorder correlates with childhood trauma and dissociative symptoms. Hum Brain Mapp. 2015 May; 36(5):1692-704. View in: PubMed

Madsen SK, Zai A, Pirnia T, Arienzo D, Zhan L, Moody TD, Thompson PM, Feusner JD. Cortical thickness and brain volumetric analysis in body dysmorphic disorder. Psychiatry Res. 2015 Apr 30; 232(1):115-22. View in: PubMed

Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, Bralten J, Brown AA, Chakravarty MM, Chen Q, Ching CR, Cuellar-Partida G, den Braber A, Giddaluru S, Goldman AL, Grimm O, Guadalupe T, Hass J, Woldehawariat G, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kim S, Klein M, Kraemer B, Lee PH, Olde Loohuis LM, Luciano M, Macare C, Mather KA, Mattheisen M, Milaneschi Y, Nho K, Papmeyer M, Ramasamy A, Risacher SL, Roiz-Santiañez R, Rose EJ, Salami A, Sämann PG, Schmaal L, Schork AJ, Shin J, Strike LT, Teumer A, van Donkelaar MM, van Eijk KR, Walters RK, Westlye LT, Whelan CD, Winkler AM, Zwiers MP, Alhusaini S, Athanasiu L, Ehrlich S, Hakobjan MM, Hartberg CB, Haukvik UK, Heister AJ, Hoehn D, Kasperaviciute D, Liewald DC, Lopez LM, Makkinje RR, Matarin M, Naber MA, McKay DR, Needham M, Nugent AC, Pütz B, Royle NA, Shen L, Sprooten E, Trabzuni D, van der Marel SS, van Hulzen KJ, Walton E, Wolf C, Almasy L, Ames D, Arepalli S, Assareh AA, Bastin ME, Brodaty H, Bulayeva KB, Carless MA, Cichon S, Corvin A, Curran JE, Czisch M, de Zubicaray GI, Dillman A, Duggirala R, Dyer TD, Erk S, Fedko IO, Ferrucci L, Foroud TM, Fox PT, Fukunaga M, Gibbs JR, Göring HH, Green RC, Guelfi S, Hansell NK, Hartman CA, Hegenscheid K, Heinz A, Hernandez DG, Heslenfeld DJ, Hoekstra PJ, Holsboer F, Homuth G, Hottenga JJ, Ikeda M, Jack CR, Jenkinson M, Johnson R, Kanai R, Keil M, Kent JW, Kochunov P, Kwok JB, Lawrie SM, Liu X, Longo DL, McMahon KL, Meisenzahl E, Melle I, Mohnke S, Montgomery GW, Mostert JC, Mühleisen TW, Nalls MA, Nichols TE, Nilsson LG, Nöthen MM, Ohi K, Olvera RL, Perez-Iglesias R, Pike GB, Potkin SG, Reinvang I, Reppermund S, Rietschel M, Romanczuk-Seiferth N, Rosen GD, Rujescu D, Schnell K, Schofield PR, Smith C, Steen VM, Sussmann JE, Thalamuthu A, Toga AW, Traynor BJ, Troncoso J, Turner JA, Valdés Hernández MC, van 't Ent D, van der Brug M, van der Wee NJ, van Tol MJ, Veltman DJ, Wassink TH, Westman E, Zielke RH, Zonderman AB, Ashbrook DG, Hager R, Lu L, McMahon FJ, Morris DW, Williams RW, Brunner HG, Buckner RL, Buitelaar JK, Cahn W, Calhoun VD, Cavalleri GL, Crespo-Facorro B, Dale AM, Davies GE, Delanty N, Depondt C, Djurovic S, Drevets WC, Espeseth T, Gollub RL, Ho BC, Hoffmann W, Hosten N, Kahn RS, Le Hellard S, Meyer-Lindenberg A, Müller-Myhsok B, Nauck M, Nyberg L, Pandolfo M, Penninx BW, Roffman JL, Sisodiya SM, Smoller JW, van Bokhoven H, van Haren NE, Völzke H, Walter H, Weiner MW, Wen W, White T, Agartz I, Andreassen OA, Blangero J, Boomsma DI, Brouwer RM, Cannon DM, Cookson MR, de Geus EJ, Deary IJ, Donohoe G, Fernández G, Fisher SE, Francks C, Glahn DC, Grabe HJ, Gruber O, Hardy J, Hashimoto R, Hulshoff Pol HE, Jönsson EG, Kloszewska I, Lovestone S, Mattay VS, Mecocci P, McDonald C, McIntosh AM, Ophoff RA, Paus T, Pausova Z, Ryten M, Sachdev PS, Saykin AJ, Simmons A, Singleton A, Soininen H, Wardlaw JM, Weale ME, Weinberger DR, Adams HH, Launer LJ, Seiler S, Schmidt R, Chauhan G, Satizabal CL, Becker JT, Yanek L, van der Lee SJ, Ebling M, Fischl B, Longstreth WT, Greve D, Schmidt H, Nyquist P, Vinke LN, van Duijn CM, Xue L, Mazoyer B, Bis JC, Gudnason V, Seshadri S, Ikram MA. Common genetic variants influence human subcortical brain structures. Nature. 2015 Apr 9; 520(7546):224-9. View in: PubMed

Yang Y, Narr KL, Baker LA, Joshi SH, Jahanshad N, Raine A, Thompson PM. Frontal and striatal alterations associated with psychopathic traits in adolescents. Psychiatry Res. 2015 Mar 30; 231(3):333-40. View in: PubMed

Apostolova LG, Hwang KS, Avila D, Elashoff D, Kohannim O, Teng E, Sokolow S, Jack CR, Jagust WJ, Shaw L, Trojanowski JQ, Weiner MW, Thompson PM. Brain amyloidosis ascertainment from cognitive, imaging, and peripheral blood protein measures. Neurology. 2015 Feb 17; 84(7):729-37. View in: PubMed

Leung KK, Malone IM, Ourselin S, Gunter JL, Bernstein MA, Thompson PM, Jack CR, Weiner MW, Fox NC. Effects of changing from non-accelerated to accelerated MRI for follow-up in brain atrophy measurement. Neuroimage. 2015 Feb 15; 107:46-53. View in: PubMed

Su Y, Blazey TM, Snyder AZ, Raichle ME, Marcus DS, Ances BM, Bateman RJ, Cairns NJ, Aldea P, Cash L, Christensen JJ, Friedrichsen K, Hornbeck RC, Farrar AM, Owen CJ, Mayeux R, Brickman AM, Klunk W, Price JC, Thompson PM, Ghetti B, Saykin AJ, Sperling RA, Johnson KA, Schofield PR, Buckles V, Morris JC, Benzinger TL. Partial volume correction in quantitative amyloid imaging. Neuroimage. 2015 Feb 15; 107:55-64. View in: PubMed

Babiloni C, Del Percio C, Boccardi M, Lizio R, Lopez S, Carducci F, Marzano N, Soricelli A, Ferri R, Triggiani AI, Prestia A, Salinari S, Rasser PE, Basar E, Famà F, Nobili F, Yener G, Emek-Savas DD, Gesualdo L, Mundi C, Thompson PM, Rossini PM, Frisoni GB. Occipital sources of resting-state alpha rhythms are related to local gray matter density in subjects with amnesic mild cognitive impairment and Alzheimer's disease. Neurobiol Aging. 2015 Feb; 36(2):556-70. View in: PubMed

Gutman BA, Fletcher PT, Cardoso MJ, Fleishman GM, Lorenzi M, Thompson PM, Ourselin S. A Riemannian Framework for Intrinsic Comparison of Closed Genus-Zero Shapes. Inf Process Med Imaging. 2015; 24:205-18. View in: PubMed

Riverol M, Becker JT, López OL, Raji CA, Thompson PM, Carmichael OT, Gach HM, Longstreth WT, Fried L, Tracy RP, Kuller LH. Relationship between Systemic and Cerebral Vascular Disease and Brain Structure Integrity in Normal Elderly Individuals. J Alzheimers Dis. 2015; 44(1):319-28. View in: PubMed

Prestia A, Cavedo E, Boccardi M, Muscio C, Adorni A, Geroldi C, Bonetti M, Thompson PM, Frisoni GB. Hippocampal and amygdalar local structural differences in elderly patients with schizophrenia. Am J Geriatr Psychiatry. 2015 Jan; 23(1):47-58. View in: PubMed

Daianu M, Jacobs RE, Weitz TM, Town TC, Thompson PM. Multi-Shell Hybrid Diffusion Imaging (HYDI) at 7 Tesla in TgF344-AD Transgenic Alzheimer Rats. PLoS One. 2015; 10(12):e0145205. View in: PubMed

Scott JA, Braskie MN, Tosun D, Thompson PM, Weiner M, DeCarli C, Carmichael OT. Cerebral Amyloid and Hypertension are Independently Associated with White Matter Lesions in Elderly. Front Aging Neurosci. 2015; 7:221. View in: PubMed

Wade BS, Valcour VG, Wendelken-Riegelhaupt L, Esmaeili-Firidouni P, Joshi SH, Gutman BA, Thompson PM. Mapping abnormal subcortical brain morphometry in an elderly HIV + cohort. Neuroimage Clin. 2015; 9:564-73. View in: PubMed

Zhan L, Liu Y, Wang Y, Zhou J, Jahanshad N, Ye J, Thompson PM. Boosting brain connectome classification accuracy in Alzheimer's disease using higher-order singular value decomposition. Front Neurosci. 2015; 9:257. View in: PubMed

Fleishman GM, Gutman BA, Fletcher PT, Thompson PM. Simultaneous Longitudinal Registration with Group-Wise Similarity Prior. Inf Process Med Imaging. 2015; 24:746-57. View in: PubMed

Cole JH, Filippetti ML, Allin MP, Walshe M, Nam KW, Gutman BA, Murray RM, Rifkin L, Thompson PM, Nosarti C. Subregional Hippocampal Morphology and Psychiatric Outcome in Adolescents Who Were Born Very Preterm and at Term. PLoS One. 2015; 10(6):e0130094. View in: PubMed

Yang Y, Wang P, Baker LA, Narr KL, Joshi SH, Hafzalla G, Raine A, Thompson PM. Thicker temporal cortex associates with a developmental trajectory for psychopathic traits in adolescents. PLoS One. 2015; 10(5):e0127025. View in: PubMed

Zhan L, Zhou J, Wang Y, Jin Y, Jahanshad N, Prasad G, Nir TM, Leonardo CD, Ye J, Thompson PM. Comparison of nine tractography algorithms for detecting abnormal structural brain networks in Alzheimer's disease. Front Aging Neurosci. 2015; 7:48. View in: PubMed

Memarian N, Madsen SK, Macey PM, Fried I, Engel J, Thompson PM, Staba RJ. Ictal depth EEG and MRI structural evidence for two different epileptogenic networks in mesial temporal lobe epilepsy. PLoS One. 2015; 10(4):e0123588. View in: PubMed

Luders E, Thompson PM, Kurth F. Larger hippocampal dimensions in meditation practitioners: differential effects in women and men. Front Psychol. 2015; 6:186. View in: PubMed

Sacchet MD, Prasad G, Foland-Ross LC, Thompson PM, Gotlib IH. Support vector machine classification of major depressive disorder using diffusion-weighted neuroimaging and graph theory. Front Psychiatry. 2015; 6:21. View in: PubMed

Teng E, Chow N, Hwang KS, Thompson PM, Gylys KH, Cole GM, Jack CR, Shaw LM, Trojanowski JQ, Soares HD, Weiner MW, Apostolova LG. Low Plasma ApoE Levels Are Associated with Smaller Hippocampal Size in the Alzheimer's Disease Neuroimaging Initiative Cohort. Dement Geriatr Cogn Disord. 2015; 39(3-4):154-66. View in: PubMed

Dennis EL, Jin Y, Villalon-Reina JE, Zhan L, Kernan CL, Babikian T, Mink RB, Babbitt CJ, Johnson JL, Giza CC, Thompson PM, Asarnow RF. White matter disruption in moderate/severe pediatric traumatic brain injury: Advanced tract-based analyses. Neuroimage Clin. 2015; 7:493-505. View in: PubMed

Moon SW, Dinov ID, Zamanyan A, Shi R, Genco A, Hobel S, Thompson PM, Toga AW. Gene interactions and structural brain change in early-onset Alzheimer's disease subjects using the pipeline environment. Psychiatry Investig. 2015 Jan; 12(1):125-35. View in: PubMed

Ching CR, Hua X, Hibar DP, Ward CP, Gunter JL, Bernstein MA, Jack CR, Weiner MW, Thompson PM. Does MRI scan acceleration affect power to track brain change? Neurobiol Aging. 2015 Jan; 36 Suppl 1:S167-77. View in: PubMed

Gutman BA, Wang Y, Yanovsky I, Hua X, Toga AW, Jack CR, Weiner MW, Thompson PM. Empowering imaging biomarkers of Alzheimer's disease. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S69-80. View in: PubMed

Boyle CP, Raji CA, Erickson KI, Lopez OL, Becker JT, Gach HM, Longstreth WT, Teverovskiy L, Kuller LH, Carmichael OT, Thompson PM. Physical activity, body mass index, and brain atrophy in Alzheimer's disease. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S194-202. View in: PubMed

Madsen SK, Rajagopalan P, Joshi SH, Toga AW, Thompson PM. Higher homocysteine associated with thinner cortical gray matter in 803 participants from the Alzheimer's Disease Neuroimaging Initiative. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S203-10. View in: PubMed

Prasad G, Joshi SH, Nir TM, Toga AW, Thompson PM. Brain connectivity and novel network measures for Alzheimer's disease classification. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S121-31. View in: PubMed

Jahanshad N, Nir TM, Toga AW, Jack CR, Bernstein MA, Weiner MW, Thompson PM. Seemingly unrelated regression empowers detection of network failure in dementia. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S103-12. View in: PubMed

Hibar DP, Stein JL, Jahanshad N, Kohannim O, Hua X, Toga AW, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ. Genome-wide interaction analysis reveals replicated epistatic effects on brain structure. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S151-8. View in: PubMed

Madsen SK, Gutman BA, Joshi SH, Toga AW, Jack CR, Weiner MW, Thompson PM. Mapping ventricular expansion onto cortical gray matter in older adults. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S32-41. View in: PubMed

Nir TM, Villalon-Reina JE, Prasad G, Jahanshad N, Joshi SH, Toga AW, Bernstein MA, Jack CR, Weiner MW, Thompson PM. Diffusion weighted imaging-based maximum density path analysis and classification of Alzheimer's disease. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S132-40. View in: PubMed

Nir TM, Jahanshad N, Toga AW, Bernstein MA, Jack CR, Weiner MW, Thompson PM. Connectivity network measures predict volumetric atrophy in mild cognitive impairment. Neurobiol Aging. 2015 Jan; 36 Suppl 1:S113-20. View in: PubMed

Shi J, Stonnington CM, Thompson PM, Chen K, Gutman B, Reschke C, Baxter LC, Reiman EM, Caselli RJ, Wang Y. Studying ventricular abnormalities in mild cognitive impairment with hyperbolic Ricci flow and tensor-based morphometry. Neuroimage. 2015 Jan 1; 104:1-20. View in: PubMed

Toga AW, Thompson PM. Connectopathy in ageing and dementia. Brain. 2014 Dec; 137(Pt 12):3104-6. View in: PubMed

Dennis EL, Jahanshad N, Braskie MN, Warstadt NM, Hibar DP, Kohannim O, Nir TM, McMahon KL, de Zubicaray GI, Montgomery GW, Martin NG, Toga AW, Wright MJ, Thompson PM. Obesity gene NEGR1 associated with white matter integrity in healthy young adults. Neuroimage. 2014 Nov 15; 102 Pt 2:548-57. View in: PubMed

Couvy-Duchesne B, Blokland GA, Hickie IB, Thompson PM, Martin NG, de Zubicaray GI, McMahon KL, Wright MJ. Heritability of head motion during resting state functional MRI in 462 healthy twins. Neuroimage. 2014 Nov 15; 102 Pt 2:424-34. View in: PubMed

Xiang S, Yuan L, Fan W, Wang Y, Thompson PM, Ye J. Bi-level multi-source learning for heterogeneous block-wise missing data. Neuroimage. 2014 Nov 15; 102 Pt 1:192-206. View in: PubMed

Warstadt NM, Dennis EL, Jahanshad N, Kohannim O, Nir TM, McMahon KL, de Zubicaray GI, Montgomery GW, Henders AK, Martin NG, Whitfield JB, Jack CR, Bernstein MA, Weiner MW, Toga AW, Wright MJ, Thompson PM. Serum cholesterol and variant in cholesterol-related gene CETP predict white matter microstructure. Neurobiol Aging. 2014 Nov; 35(11):2504-13. View in: PubMed

Prasad G, Joshi AA, Feng A, Toga AW, Thompson PM, Terzopoulos D. Skull-stripping with machine learning deformable organisms. J Neurosci Methods. 2014 Oct 30; 236:114-24. View in: PubMed

Shen KK, Rose S, Fripp J, McMahon KL, de Zubicaray GI, Martin NG, Thompson PM, Wright MJ, Salvado O. Investigating brain connectivity heritability in a twin study using diffusion imaging data. Neuroimage. 2014 Oct; 100:628-41. View in: PubMed

Raji CA, Erickson KI, Lopez OL, Kuller LH, Gach HM, Thompson PM, Riverol M, Becker JT. Regular fish consumption and age-related brain gray matter loss. Am J Prev Med. 2014 Oct; 47(4):444-51. View in: PubMed

Jin Y, Shi Y, Zhan L, Gutman BA, de Zubicaray GI, McMahon KL, Wright MJ, Toga AW, Thompson PM. Automatic clustering of white matter fibers in brain diffusion MRI with an application to genetics. Neuroimage. 2014 Oct; 100:75-90. View in: PubMed

Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, Ourselin S, Schofield PR, Masters CL, Martins RN, Weiner MW, Thompson PM, Fox NC, Koeppe RA, Jack CR, Mathis CA, Oliver A, Blazey TM, Moulder K, Buckles V, Hornbeck R, Chhatwal J, Schultz AP, Goate AM, Fagan AM, Cairns NJ, Marcus DS, Morris JC, Ances BM. Functional connectivity in autosomal dominant and late-onset Alzheimer disease. JAMA Neurol. 2014 Sep 1; 71(9):1111-22. View in: PubMed

Adogwa O, Huang MI, Thompson PM, Darlington T, Cheng JS, Gokaslan ZL, Gottfried ON, Bagley CA, Anderson GD, Isaacs RE. No difference in postoperative complications, pain, and functional outcomes up to 2 years after incidental durotomy in lumbar spinal fusion: a prospective, multi-institutional, propensity-matched analysis of 1,741 patients. Spine J. 2014 Sep 1; 14(9):1828-34. View in: PubMed

Cavedo E, Pievani M, Boccardi M, Galluzzi S, Bocchetta M, Bonetti M, Thompson PM, Frisoni GB. Medial temporal atrophy in early and late-onset Alzheimer's disease. Neurobiol Aging. 2014 Sep; 35(9):2004-12. View in: PubMed

Prasad G, Joshi SH, Jahanshad N, Villalon-Reina J, Aganj I, Lenglet C, Sapiro G, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Toga AW, Thompson PM. Automatic clustering and population analysis of white matter tracts using maximum density paths. Neuroimage. 2014 Aug 15; 97:284-95. View in: PubMed

Shi J, Leporé N, Gutman BA, Thompson PM, Baxter LC, Caselli RJ, Wang Y. Genetic influence of apolipoprotein E4 genotype on hippocampal morphometry: An N = 725 surface-based Alzheimer's disease neuroimaging initiative study. Hum Brain Mapp. 2014 Aug; 35(8):3903-18. View in: PubMed

Kochunov P, Jahanshad N, Sprooten E, Nichols TE, Mandl RC, Almasy L, Booth T, Brouwer RM, Curran JE, de Zubicaray GI, Dimitrova R, Duggirala R, Fox PT, Elliot Hong L, Landman BA, Lemaitre H, Lopez LM, Martin NG, McMahon KL, Mitchell BD, Olvera RL, Peterson CP, Starr JM, Sussmann JE, Toga AW, Wardlaw JM, Wright MJ, Wright SN, Bastin ME, McIntosh AM, Boomsma DI, Kahn RS, den Braber A, de Geus EJ, Deary IJ, Hulshoff Pol HE, Williamson DE, Blangero J, van 't Ent D, Thompson PM, Glahn DC. Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling. Neuroimage. 2014 Jul 15; 95:136-50. View in: PubMed

Guillaume B, Hua X, Thompson PM, Waldorp L, Nichols TE. Fast and accurate modelling of longitudinal and repeated measures neuroimaging data. Neuroimage. 2014 Jul; 94:287-302. View in: PubMed

Schwarz CG, Reid RI, Gunter JL, Senjem ML, Przybelski SA, Zuk SM, Whitwell JL, Vemuri P, Josephs KA, Kantarci K, Thompson PM, Petersen RC, Jack CR. Improved DTI registration allows voxel-based analysis that outperforms Tract-Based Spatial Statistics. Neuroimage. 2014 Jul; 94:65-78. View in: PubMed

Roussotte FF, Gutman BA, Madsen SK, Colby JB, Narr KL, Thompson PM. The apolipoprotein E epsilon 4 allele is associated with ventricular expansion rate and surface morphology in dementia and normal aging. Neurobiol Aging. 2014 Jun; 35(6):1309-17. View in: PubMed

Shen L, Thompson PM, Potkin SG, Bertram L, Farrer LA, Foroud TM, Green RC, Hu X, Huentelman MJ, Kim S, Kauwe JS, Li Q, Liu E, Macciardi F, Moore JH, Munsie L, Nho K, Ramanan VK, Risacher SL, Stone DJ, Swaminathan S, Toga AW, Weiner MW, Saykin AJ. Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers. Brain Imaging Behav. 2014 Jun; 8(2):183-207. View in: PubMed

Roussotte FF, Daianu M, Jahanshad N, Leonardo CD, Thompson PM. Neuroimaging and genetic risk for Alzheimer's disease and addiction-related degenerative brain disorders. Brain Imaging Behav. 2014 Jun; 8(2):217-33. View in: PubMed

Peng DX, Kelley RG, Quintin EM, Raman M, Thompson PM, Reiss AL. Cognitive and behavioral correlates of caudate subregion shape variation in fragile X syndrome. Hum Brain Mapp. 2014 Jun; 35(6):2861-8. View in: PubMed

Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, Almasy L, Almeida J, Alpert K, Andreasen NC, Andreassen OA, Apostolova LG, Appel K, Armstrong NJ, Aribisala B, Bastin ME, Bauer M, Bearden CE, Bergmann O, Binder EB, Blangero J, Bockholt HJ, Bøen E, Bois C, Boomsma DI, Booth T, Bowman IJ, Bralten J, Brouwer RM, Brunner HG, Brohawn DG, Buckner RL, Buitelaar J, Bulayeva K, Bustillo JR, Calhoun VD, Cannon DM, Cantor RM, Carless MA, Caseras X, Cavalleri GL, Chakravarty MM, Chang KD, Ching CR, Christoforou A, Cichon S, Clark VP, Conrod P, Coppola G, Crespo-Facorro B, Curran JE, Czisch M, Deary IJ, de Geus EJ, den Braber A, Delvecchio G, Depondt C, de Haan L, de Zubicaray GI, Dima D, Dimitrova R, Djurovic S, Dong H, Donohoe G, Duggirala R, Dyer TD, Ehrlich S, Ekman CJ, Elvsåshagen T, Emsell L, Erk S, Espeseth T, Fagerness J, Fears S, Fedko I, Fernández G, Fisher SE, Foroud T, Fox PT, Francks C, Frangou S, Frey EM, Frodl T, Frouin V, Garavan H, Giddaluru S, Glahn DC, Godlewska B, Goldstein RZ, Gollub RL, Grabe HJ, Grimm O, Gruber O, Guadalupe T, Gur RE, Gur RC, Göring HH, Hagenaars S, Hajek T, Hall GB, Hall J, Hardy J, Hartman CA, Hass J, Hatton SN, Haukvik UK, Hegenscheid K, Heinz A, Hickie IB, Ho BC, Hoehn D, Hoekstra PJ, Hollinshead M, Holmes AJ, Homuth G, Hoogman M, Hong LE, Hosten N, Hottenga JJ, Hulshoff Pol HE, Hwang KS, Jack CR, Jenkinson M, Johnston C, Jönsson EG, Kahn RS, Kasperaviciute D, Kelly S, Kim S, Kochunov P, Koenders L, Krämer B, Kwok JB, Lagopoulos J, Laje G, Landen M, Landman BA, Lauriello J, Lawrie SM, Lee PH, Le Hellard S, Lemaître H, Leonardo CD, Li CS, Liberg B, Liewald DC, Liu X, Lopez LM, Loth E, Lourdusamy A, Luciano M, Macciardi F, Machielsen MW, Macqueen GM, Malt UF, Mandl R, Manoach DS, Martinot JL, Matarin M, Mather KA, Mattheisen M, Mattingsdal M, Meyer-Lindenberg A, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Meisenzahl E, Melle I, Milaneschi Y, Mohnke S, Montgomery GW, Morris DW, Moses EK, Mueller BA, Muñoz Maniega S, Mühleisen TW, Müller-Myhsok B, Mwangi B, Nauck M, Nho K, Nichols TE, Nilsson LG, Nugent AC, Nyberg L, Olvera RL, Oosterlaan J, Ophoff RA, Pandolfo M, Papalampropoulou-Tsiridou M, Papmeyer M, Paus T, Pausova Z, Pearlson GD, Penninx BW, Peterson CP, Pfennig A, Phillips M, Pike GB, Poline JB, Potkin SG, Pütz B, Ramasamy A, Rasmussen J, Rietschel M, Rijpkema M, Risacher SL, Roffman JL, Roiz-Santiañez R, Romanczuk-Seiferth N, Rose EJ, Royle NA, Rujescu D, Ryten M, Sachdev PS, Salami A, Satterthwaite TD, Savitz J, Saykin AJ, Scanlon C, Schmaal L, Schnack HG, Schork AJ, Schulz SC, Schür R, Seidman L, Shen L, Shoemaker JM, Simmons A, Sisodiya SM, Smith C, Smoller JW, Soares JC, Sponheim SR, Sprooten E, Starr JM, Steen VM, Strakowski S, Strike L, Sussmann J, Sämann PG, Teumer A, Toga AW, Tordesillas-Gutierrez D, Trabzuni D, Trost S, Turner J, Van den Heuvel M, van der Wee NJ, van Eijk K, van Erp TG, van Haren NE, van 't Ent D, van Tol MJ, Valdés Hernández MC, Veltman DJ, Versace A, Völzke H, Walker R, Walter H, Wang L, Wardlaw JM, Weale ME, Weiner MW, Wen W, Westlye LT, Whalley HC, Whelan CD, White T, Winkler AM, Wittfeld K, Woldehawariat G, Wolf C, Zilles D, Zwiers MP, Thalamuthu A, Schofield PR, Freimer NB, Lawrence NS, Drevets W. The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav. 2014 Jun; 8(2):153-82. View in: PubMed

Medland SE, Jahanshad N, Neale BM, Thompson PM. Whole-genome analyses of whole-brain data: working within an expanded search space. Nat Neurosci. 2014 Jun; 17(6):791-800. View in: PubMed

Roussotte FF, Gutman BA, Madsen SK, Colby JB, Thompson PM. Combined Effects of Alzheimer Risk Variants in the CLU and ApoE Genes on Ventricular Expansion Patterns in the Elderly. J Neurosci. 2014 May 7; 34(19):6537-45. View in: PubMed

Gadelkarim JJ, Ajilore O, Schonfeld D, Zhan L, Thompson PM, Feusner JD, Kumar A, Altshuler LL, Leow AD. Investigating brain community structure abnormalities in bipolar disorder using path length associated community estimation. Hum Brain Mapp. 2014 May; 35(5):2253-64. View in: PubMed

Hurtz S, Woo E, Kebets V, Green AE, Zoumalan C, Wang B, Ringman JM, Thompson PM, Apostolova LG. Age effects on cortical thickness in cognitively normal elderly individuals. Dement Geriatr Cogn Dis Extra. 2014 May; 4(2):221-7. View in: PubMed

Looi JC, Walterfang M, Nilsson C, Power BD, van Westen D, Velakoulis D, Wahlund LO, Thompson PM. The subcortical connectome: hubs, spokes and the space between - a vision for further research in neurodegenerative disease. Aust N Z J Psychiatry. 2014 Apr; 48(4):306-9. View in: PubMed

Fears SC, Service SK, Kremeyer B, Araya C, Araya X, Bejarano J, Ramirez M, Castrillón G, Gomez-Franco J, Lopez MC, Montoya G, Montoya P, Aldana I, Teshiba TM, Abaryan Z, Al-Sharif NB, Ericson M, Jalbrzikowski M, Luykx JJ, Navarro L, Tishler TA, Altshuler L, Bartzokis G, Escobar J, Glahn DC, Ospina-Duque J, Risch N, Ruiz-Linares A, Thompson PM, Cantor RM, Lopez-Jaramillo C, Macaya G, Molina J, Reus VI, Sabatti C, Freimer NB, Bearden CE. Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees. JAMA Psychiatry. 2014 Apr 1; 71(4):375-87. View in: PubMed

Roussotte FF, Jahanshad N, Hibar DP, Sowell ER, Kohannim O, Barysheva M, Hansell NK, McMahon KL, de Zubicaray GI, Montgomery GW, Martin NG, Wright MJ, Toga AW, Jack CR, Weiner MW, Thompson PM. A commonly carried genetic variant in the delta opioid receptor gene, OPRD1, is associated with smaller regional brain volumes: Replication in elderly and young populations. Hum Brain Mapp. 2014 Apr; 35(4):1226-36. View in: PubMed

Braskie MN, Thompson PM. A focus on structural brain imaging in the Alzheimer's disease neuroimaging initiative. Biol Psychiatry. 2014 Apr 1; 75(7):527-33. View in: PubMed

Dennis EL, Jahanshad N, McMahon KL, de Zubicaray GI, Martin NG, Hickie IB, Toga AW, Wright MJ, Thompson PM. Development of insula connectivity between ages 12 and 30 revealed by high angular resolution diffusion imaging. Hum Brain Mapp. 2014 Apr; 35(4):1790-800. View in: PubMed

Dennis EL, Thompson PM. Functional brain connectivity using FMRI in aging and Alzheimer's disease. Neuropsychol Rev. 2014 Mar; 24(1):49-62. View in: PubMed

Haas BW, Sheau K, Kelley RG, Thompson PM, Reiss AL. Regionally specific increased volume of the amygdala in Williams syndrome: Evidence from surface-based modeling. Hum Brain Mapp. 2014 Mar; 35(3):866-74. View in: PubMed

Nir TM, Jahanshad N, Busovaca E, Wendelken L, Nicolas K, Thompson PM, Valcour VG. Mapping white matter integrity in elderly people with HIV. Hum Brain Mapp. 2014 Mar; 35(3):975-92. View in: PubMed

Dubey R, Zhou J, Wang Y, Thompson PM, Ye J. Analysis of sampling techniques for imbalanced data: An n=648 ADNI study. Neuroimage. 2014 Feb 15; 87:220-41. View in: PubMed

Dennis EL, Thompson PM. Reprint of: Mapping connectivity in the developing brain. Int J Dev Neurosci. 2014 Feb; 32:41-57. View in: PubMed

Cetingul HE, Wright MJ, Thompson PM, Vidal R. Segmentation of high angular resolution diffusion MRI using sparse riemannian manifold clustering. IEEE Trans Med Imaging. 2014 Feb; 33(2):301-17. View in: PubMed

Shan ZY, Wright MJ, Thompson PM, McMahon KL, Blokland GG, de Zubicaray GI, Martin NG, Vinkhuyzen AA, Reutens DC. Modeling of the hemodynamic responses in block design fMRI studies. J Cereb Blood Flow Metab. 2014 Feb; 34(2):316-24. View in: PubMed

Blokland GA, McMahon KL, Thompson PM, Hickie IB, Martin NG, de Zubicaray GI, Wright MJ. Genetic effects on the cerebellar role in working memory: Same brain, different genes? Neuroimage. 2014 Feb 1; 86:392-403. View in: PubMed

Ashbrook DG, Williams RW, Lu L, Stein JL, Hibar DP, Nichols TE, Medland SE, Thompson PM, Hager R. Joint genetic analysis of hippocampal size in mouse and human identifies a novel gene linked to neurodegenerative disease. BMC Genomics. 2014; 15(1):850. View in: PubMed

Lee GJ, Lu PH, Mather MJ, Shapira J, Jimenez E, Leow AD, Thompson PM, Mendez MF. Neuroanatomical correlates of emotional blunting in behavioral variant frontotemporal dementia and early-onset Alzheimer's disease. J Alzheimers Dis. 2014; 41(3):793-800. View in: PubMed

Fulham WR, Michie PT, Ward PB, Rasser PE, Todd J, Johnston PJ, Thompson PM, Schall U. Mismatch negativity in recent-onset and chronic schizophrenia: a current source density analysis. PLoS One. 2014; 9(6):e100221. View in: PubMed

Wade BS, Joshi SH, Reuter M, Blumenthal JD, Toga AW, Thompson PM, Giedd JN. Effects of sex chromosome dosage on corpus callosum morphology in supernumerary sex chromosome aneuploidies. Biol Sex Differ. 2014; 5:16. View in: PubMed

Walterfang M, Luders E, Looi JC, Rajagopalan P, Velakoulis D, Thompson PM, Lindberg O, Ostberg P, Nordin LE, Svensson L, Wahlund LO. Shape analysis of the corpus callosum in Alzheimer's disease and frontotemporal lobar degeneration subtypes. J Alzheimers Dis. 2014; 40(4):897-906. View in: PubMed

Jalbrzikowski M, Villalon-Reina JE, Karlsgodt KH, Senturk D, Chow C, Thompson PM, Bearden CE. Altered white matter microstructure is associated with social cognition and psychotic symptoms in 22q11. 2 microdeletion syndrome. Front Behav Neurosci. 2014; 8:393. View in: PubMed

Luders E, Toga AW, Thompson PM. Why size matters: Differences in brain volume account for apparent sex differences in callosal anatomy: The sexual dimorphism of the corpus callosum. Neuroimage. 2014 Jan; 84:820-4. View in: PubMed

Sacchet MD, Prasad G, Foland-Ross LC, Joshi SH, Hamilton JP, Thompson PM, Gotlib IH. Structural abnormality of the corticospinal tract in major depressive disorder. Biol Mood Anxiety Disord. 2014; 4:8. View in: PubMed

Apostolova LG, Hwang KS, Kohannim O, Avila D, Elashoff D, Jack CR, Shaw L, Trojanowski JQ, Weiner MW, Thompson PM. ApoE4 effects on automated diagnostic classifiers for mild cognitive impairment and Alzheimer's disease. Neuroimage Clin. 2014; 4:461-72. View in: PubMed

Schneider C, Helmstaedter C, Luders E, Thompson PM, Toga AW, Elger C, Weber B. Relation of callosal structure to cognitive abilities in temporal lobe epilepsy. Front Neurol. 2014; 5:16. View in: PubMed

Dean DC, Jerskey BA, Chen K, Protas H, Thiyyagura P, Roontiva A, O'Muircheartaigh J, Dirks H, Waskiewicz N, Lehman K, Siniard AL, Turk MN, Hua X, Madsen SK, Thompson PM, Fleisher AS, Huentelman MJ, Deoni SC, Reiman EM. Brain Differences in Infants at Differential Genetic Risk for Late-Onset Alzheimer Disease: A Cross-sectional Imaging Study. JAMA Neurol. 2014 Jan 1; 71(1):11-22. View in: PubMed

Lu PH, Lee GJ, Shapira J, Jimenez E, Mather MJ, Thompson PM, Bartzokis G, Mendez MF. Regional differences in white matter breakdown between frontotemporal dementia and early-onset Alzheimer's disease. J Alzheimers Dis. 2014 Jan 1; 39(2):261-9. View in: PubMed

Kumar R, Farahvar S, Ogren JA, Macey PM, Thompson PM, Woo MA, Yan-Go FL, Harper RM. Brain putamen volume changes in newly-diagnosed patients with obstructive sleep apnea. Neuroimage Clin. 2014; 4:383-91. View in: PubMed

Labus JS, Dinov ID, Jiang Z, Ashe-McNalley C, Zamanyan A, Shi Y, Hong JY, Gupta A, Tillisch K, Ebrat B, Hobel S, Gutman BA, Joshi S, Thompson PM, Toga AW, Mayer EA. Irritable bowel syndrome in female patients is associated with alterations in structural brain networks. Pain. 2014 Jan; 155(1):137-49. View in: PubMed

Braskie MN, Medina LD, Rodriguez-Agudelo Y, Geschwind DH, Macias-Islas MA, Thompson PM, Cummings JL, Bookheimer SY, Ringman JM. Memory performance and fMRI signal in presymptomatic familial Alzheimer's disease. Hum Brain Mapp. 2013 Dec; 34(12):3308-19. View in: PubMed

Jahanshad N, Rajagopalan P, Thompson PM. Neuroimaging, nutrition, and iron-related genes. Cell Mol Life Sci. 2013 Dec; 70(23):4449-61. View in: PubMed

Luders E, Thompson PM, Kurth F, Hong JY, Phillips OR, Wang Y, Gutman BA, Chou YY, Narr KL, Toga AW. Global and regional alterations of hippocampal anatomy in long-term meditation practitioners. Hum Brain Mapp. 2013 Dec; 34(12):3369-75. View in: PubMed

Benzinger TL, Blazey T, Jack CR, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, Christensen JJ, Ercole L, Hornbeck RC, Farrar AM, Aldea P, Jasielec MS, Owen CJ, Xie X, Mayeux R, Brickman A, McDade E, Klunk W, Mathis CA, Ringman J, Thompson PM, Ghetti B, Saykin AJ, Sperling RA, Johnson KA, Salloway S, Correia S, Schofield PR, Masters CL, Rowe C, Villemagne VL, Martins R, Ourselin S, Rossor MN, Fox NC, Cash DM, Weiner MW, Holtzman DM, Buckles VD, Moulder K, Morris JC. Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):E4502-9. View in: PubMed

Braskie MN, Kohannim O, Jahanshad N, Chiang MC, Barysheva M, Toga AW, Ringman JM, Montgomery GW, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Thompson PM. Relation between variants in the neurotrophin receptor gene, NTRK3, and white matter integrity in healthy young adults. Neuroimage. 2013 Nov 15; 82:146-53. View in: PubMed

Dennis EL, Thompson PM. Mapping connectivity in the developing brain. Int J Dev Neurosci. 2013 Nov; 31(7):525-42. View in: PubMed

Villalon-Reina J, Jahanshad N, Beaton E, Toga AW, Thompson PM, Simon TJ. White matter microstructural abnormalities in girls with chromosome 22q11. 2 deletion syndrome, Fragile X or Turner syndrome as evidenced by diffusion tensor imaging. Neuroimage. 2013 Nov 1; 81:441-54. View in: PubMed

Jahanshad N, Kochunov PV, Sprooten E, Mandl RC, Nichols TE, Almasy L, Blangero J, Brouwer RM, Curran JE, de Zubicaray GI, Duggirala R, Fox PT, Hong LE, Landman BA, Martin NG, McMahon KL, Medland SE, Mitchell BD, Olvera RL, Peterson CP, Starr JM, Sussmann JE, Toga AW, Wardlaw JM, Wright MJ, Hulshoff Pol HE, Bastin ME, McIntosh AM, Deary IJ, Thompson PM, Glahn DC. Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: a pilot project of the ENIGMA-DTI working group. Neuroimage. 2013 Nov 1; 81:455-69. View in: PubMed

Rajagopalan P, Hibar DP, Thompson PM. TREM2 and neurodegenerative disease. N Engl J Med. 2013 Oct 17; 369(16):1565-7. View in: PubMed

Thompson PM, Ge T, Glahn DC, Jahanshad N, Nichols TE. Genetics of the connectome. Neuroimage. 2013 Oct 15; 80:475-88. View in: PubMed

Cash DM, Ridgway GR, Liang Y, Ryan NS, Kinnunen KM, Yeatman T, Malone IB, Benzinger TL, Jack CR, Thompson PM, Ghetti BF, Saykin AJ, Masters CL, Ringman JM, Salloway SP, Schofield PR, Sperling RA, Cairns NJ, Marcus DS, Xiong C, Bateman RJ, Morris JC, Rossor MN, Ourselin S, Fox NC. The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study. Neurology. 2013 Oct 15; 81(16):1425-33. View in: PubMed

Tesli M, Egeland R, Sønderby IE, Haukvik UK, Bettella F, Hibar DP, Thompson PM, Rimol LM, Melle I, Agartz I, Djurovic S, Andreassen OA. No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes. J Affect Disord. 2013 Oct; 151(1):291-7. View in: PubMed

Braskie MN, Thompson PM. Understanding cognitive deficits in Alzheimer's disease based on neuroimaging findings. Trends Cogn Sci. 2013 Oct; 17(10):510-6. View in: PubMed

Zhan L, Jahanshad N, Ennis DB, Jin Y, Bernstein MA, Borowski BJ, Jack CR, Toga AW, Leow AD, Thompson PM. Angular versus spatial resolution trade-offs for diffusion imaging under time constraints. Hum Brain Mapp. 2013 Oct; 34(10):2688-706. View in: PubMed

Dennis EL, Thompson PM. Typical and atypical brain development: a review of neuroimaging studies. Dialogues Clin Neurosci. 2013 Sep; 15(3):359-84. View in: PubMed

Shi J, Thompson PM, Gutman B, Wang Y. Surface fluid registration of conformal representation: application to detect disease burden and genetic influence on hippocampus. Neuroimage. 2013 Sep; 78:111-34. View in: PubMed

Kurth F, Mayer EA, Toga AW, Thompson PM, Luders E. The right inhibition? Callosal correlates of hand performance in healthy children and adolescents callosal correlates of hand performance. Hum Brain Mapp. 2013 Sep; 34(9):2259-65. View in: PubMed

Kaiser NC, Lee GJ, Lu PH, Mather MJ, Shapira J, Jimenez E, Thompson PM, Mendez MF. What dementia reveals about proverb interpretation and its neuroanatomical correlates. Neuropsychologia. 2013 Aug; 51(9):1726-33. View in: PubMed

Cherbuin N, Luders E, Chou YY, Thompson PM, Toga AW, Anstey KJ. Right, left, and center: how does cerebral asymmetry mix with callosal connectivity? Hum Brain Mapp. 2013 Jul; 34(7):1728-36. View in: PubMed

Pievani M, Bocchetta M, Boccardi M, Cavedo E, Bonetti M, Thompson PM, Frisoni GB. Striatal morphology in early-onset and late-onset Alzheimer's disease: a preliminary study. Neurobiol Aging. 2013 Jul; 34(7):1728-39. View in: PubMed

Wang Y, Yuan L, Shi J, Greve A, Ye J, Toga AW, Reiss AL, Thompson PM. Applying tensor-based morphometry to parametric surfaces can improve MRI-based disease diagnosis. Neuroimage. 2013 Jul 1; 74:209-30. View in: PubMed

Hibar DP, Stein JL, Ryles AB, Kohannim O, Jahanshad N, Medland SE, Hansell NK, McMahon KL, de Zubicaray GI, Montgomery GW, Martin NG, Wright MJ, Saykin AJ, Jack CR, Weiner MW, Toga AW, Thompson PM. Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N?=?1345 young and elderly subjects. Brain Imaging Behav. 2013 Jun; 7(2):102-15. View in: PubMed

Wyman BT, Harvey DJ, Crawford K, Bernstein MA, Carmichael O, Cole PE, Crane PK, DeCarli C, Fox NC, Gunter JL, Hill D, Killiany RJ, Pachai C, Schwarz AJ, Schuff N, Senjem ML, Suhy J, Thompson PM, Weiner M, Jack CR. Standardization of analysis sets for reporting results from ADNI MRI data. Alzheimers Dement. 2013 May; 9(3):332-7. View in: PubMed

Gutman BA, Hua X, Rajagopalan P, Chou YY, Wang Y, Yanovsky I, Toga AW, Jack CR, Weiner MW, Thompson PM. Maximizing power to track Alzheimer's disease and MCI progression by LDA-based weighting of longitudinal ventricular surface features. Neuroimage. 2013 Apr 15; 70:386-401. View in: PubMed

Rajagopalan P, Refsum H, Hua X, Toga AW, Jack CR, Weiner MW, Thompson PM. Mapping creatinine- and cystatin C-related white matter brain deficits in the elderly. Neurobiol Aging. 2013 Apr; 34(4):1221-30. View in: PubMed

Apostolova LG, Babakchanian S, Hwang KS, Green AE, Zlatev D, Chou YY, DeCarli C, Jack CR, Petersen RC, Aisen PS, Cummings JL, Toga AW, Thompson PM. Ventricular enlargement and its clinical correlates in the imaging cohort from the ADCS MCI donepezil/vitamin E study. Alzheimer Dis Assoc Disord. 2013 Apr-Jun; 27(2):174-81. View in: PubMed

Engel J, Thompson PM, Stern JM, Staba RJ, Bragin A, Mody I. Connectomics and epilepsy. Curr Opin Neurol. 2013 Apr; 26(2):186-94. View in: PubMed

Foland-Ross LC, Thompson PM, Sugar CA, Narr KL, Penfold C, Vasquez RE, Townsend J, Fischer J, Saharan P, Bearden CE, Altshuler LL. Three-dimensional mapping of hippocampal and amygdalar structure in euthymic adults with bipolar disorder not treated with lithium. Psychiatry Res. 2013 Mar 30; 211(3):195-201. View in: PubMed

Jahanshad N, Rajagopalan P, Hua X, Hibar DP, Nir TM, Toga AW, Jack CR, Saykin AJ, Green RC, Weiner MW, Medland SE, Montgomery GW, Hansell NK, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Thompson PM. Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):4768-73. View in: PubMed

Toga AW, Thompson PM. Connectomics sheds new light on Alzheimer's disease. Biol Psychiatry. 2013 Mar 1; 73(5):390-2. View in: PubMed

Beyer MK, Alves G, Hwang KS, Babakchanian S, Bronnick KS, Chou YY, Dalaker TO, Kurz MW, Larsen JP, Somme JH, Thompson PM, Tysnes OB, Apostolova LG. Cerebrospinal fluid Aß levels correlate with structural brain changes in Parkinson's disease. Mov Disord. 2013 Mar; 28(3):302-10. View in: PubMed

Boccardi M, Bocchetta M, Aronen HJ, Repo-Tiihonen E, Vaurio O, Thompson PM, Tiihonen J, Frisoni GB. Atypical nucleus accumbens morphology in psychopathy: another limbic piece in the puzzle. Int J Law Psychiatry. 2013 Mar-Apr; 36(2):157-67. View in: PubMed

Feusner JD, Arienzo D, Li W, Zhan L, Gadelkarim J, Thompson PM, Leow AD. White matter microstructure in body dysmorphic disorder and its clinical correlates. Psychiatry Res. 2013 Feb 28; 211(2):132-40. View in: PubMed

Hua X, Hibar DP, Ching CR, Boyle CP, Rajagopalan P, Gutman BA, Leow AD, Toga AW, Jack CR, Harvey D, Weiner MW, Thompson PM. Unbiased tensor-based morphometry: improved robustness and sample size estimates for Alzheimer's disease clinical trials. Neuroimage. 2013 Feb 15; 66:648-61. View in: PubMed

Hua X, Thompson PM, Leow AD, Madsen SK, Caplan R, Alger JR, O'Neill J, Joshi K, Smalley SL, Toga AW, Levitt JG. Brain growth rate abnormalities visualized in adolescents with autism. Hum Brain Mapp. 2013 Feb; 34(2):425-36. View in: PubMed

Lee GJ, Lu PH, Medina LD, Rodriguez-Agudelo Y, Melchor S, Coppola G, Braskie MN, Hua X, Apostolova LG, Leow AD, Thompson PM, Ringman JM. Regional brain volume differences in symptomatic and presymptomatic carriers of familial Alzheimer's disease mutations. J Neurol Neurosurg Psychiatry. 2013 Feb; 84(2):154-62. View in: PubMed

Lu PH, Lee GJ, Tishler TA, Meghpara M, Thompson PM, Bartzokis G. Myelin breakdown mediates age-related slowing in cognitive processing speed in healthy elderly men. Brain Cogn. 2013 Feb; 81(1):131-8. View in: PubMed

Rajagopalan P, Toga AW, Jack CR, Weiner MW, Thompson PM. Fat-mass-related hormone, plasma leptin, predicts brain volumes in the elderly. Neuroreport. 2013 Jan 23; 24(2):58-62. View in: PubMed

Hibar DP, Stein JL, Jahanshad N, Kohannim O, Toga AW, McMahon KL, de Zubicaray GI, Montgomery GW, Martin NG, Wright MJ, Weiner MW, Thompson PM. Exhaustive search of the SNP-sNP interactome identifies epistatic effects on brain volume in two cohorts. Med Image Comput Comput Assist Interv. 2013; 16(Pt 3):600-7. View in: PubMed

Shi J, Wang Y, Ceschin R, An X, Lao Y, Vanderbilt D, Nelson MD, Thompson PM, Panigrahy A, Leporé N. A multivariate surface-based analysis of the putamen in premature newborns: regional differences within the ventral striatum. PLoS One. 2013; 8(7):e66736. View in: PubMed

Hibar DP, Medland SE, Stein JL, Kim S, Shen L, Saykin AJ, de Zubicaray GI, McMahon KL, Montgomery GW, Martin NG, Wright MJ, Djurovic S, Agartz IA, Andreassen OA, Thompson PM. Genetic clustering on the hippocampal surface for genome-wide association studies. Med Image Comput Comput Assist Interv. 2013; 16(Pt 2):690-7. View in: PubMed

Hwang KS, Beyer MK, Green AE, Chung C, Thompson PM, Janvin C, Larsen JP, Aarsland D, Apostolova LG. Mapping cortical atrophy in Parkinson's disease patients with dementia. J Parkinsons Dis. 2013; 3(1):69-76. View in: PubMed

Braskie MN, Toga AW, Thompson PM. Recent advances in imaging Alzheimer's disease. J Alzheimers Dis. 2013; 33 Suppl 1:S313-27. View in: PubMed

Daianu M, Jahanshad N, Nir TM, Toga AW, Jack CR, Weiner MW, Thompson PM. Breakdown of brain connectivity between normal aging and Alzheimer's disease: a structural k-core network analysis. Brain Connect. 2013; 3(4):407-22. View in: PubMed

Grill JD, Di L, Lu PH, Lee C, Ringman J, Apostolova LG, Chow N, Kohannim O, Cummings JL, Thompson PM, Elashoff D. Estimating sample sizes for predementia Alzheimer's trials based on the Alzheimer's Disease Neuroimaging Initiative. Neurobiol Aging. 2013 Jan; 34(1):62-72. View in: PubMed

Roussotte FF, Gutman BA, Hibar DP, Jahanshad N, Madsen SK, Jack CR, Weiner MW, Thompson PM. A single nucleotide polymorphism associated with reduced alcohol intake in the RASGRF2 gene predicts larger cortical volumes but faster longitudinal ventricular expansion in the elderly. Front Aging Neurosci. 2013; 5:93. View in: PubMed

Kohannim O, Hua X, Rajagopalan P, Hibar DP, Jahanshad N, Grill JD, Apostolova LG, Toga AW, Jack CR, Weiner MW, Thompson PM. Multilocus genetic profiling to empower drug trials and predict brain atrophy. Neuroimage Clin. 2013; 2:827-35. View in: PubMed

Hua X, Boyle CP, Harezlak J, Tate DF, Yiannoutsos CT, Cohen R, Schifitto G, Gongvatana A, Zhong J, Zhu T, Taylor MJ, Campbell TB, Daar ES, Alger JR, Singer E, Buchthal S, Toga AW, Navia B, Thompson PM. Disrupted cerebral metabolite levels and lower nadir CD4 + counts are linked to brain volume deficits in 210 HIV-infected patients on stable treatment. Neuroimage Clin. 2013; 3:132-42. View in: PubMed

Nir TM, Jahanshad N, Villalon-Reina JE, Toga AW, Jack CR, Weiner MW, Thompson PM. Effectiveness of regional DTI measures in distinguishing Alzheimer's disease, MCI, and normal aging. Neuroimage Clin. 2013; 3:180-95. View in: PubMed

Zhan L, Mueller BA, Jahanshad N, Jin Y, Lenglet C, Yacoub E, Sapiro G, Ugurbil K, Harel N, Toga AW, Lim KO, Thompson PM. Magnetic resonance field strength effects on diffusion measures and brain connectivity networks. Brain Connect. 2013; 3(1):72-86. View in: PubMed

Dennis EL, Jahanshad N, McMahon KL, de Zubicaray GI, Martin NG, Hickie IB, Toga AW, Wright MJ, Thompson PM. Development of brain structural connectivity between ages 12 and 30: a 4-Tesla diffusion imaging study in 439 adolescents and adults. Neuroimage. 2013 Jan 1; 64:671-84. View in: PubMed

Lu PH, Mendez MF, Lee GJ, Leow AD, Lee HW, Shapira J, Jimenez E, Boeve BB, Caselli RJ, Graff-Radford NR, Jack CR, Kramer JH, Miller BL, Bartzokis G, Thompson PM, Knopman DS. Patterns of brain atrophy in clinical variants of frontotemporal lobar degeneration. Dement Geriatr Cogn Disord. 2013; 35(1-2):34-50. View in: PubMed

Barysheva M, Jahanshad N, Foland-Ross L, Altshuler LL, Thompson PM. White matter microstructural abnormalities in bipolar disorder: A whole brain diffusion tensor imaging study. Neuroimage Clin. 2013; 2:558-68. View in: PubMed

Beyer MK, Bronnick KS, Hwang KS, Bergsland N, Tysnes OB, Larsen JP, Thompson PM, Somme JH, Apostolova LG. Verbal memory is associated with structural hippocampal changes in newly diagnosed Parkinson's disease. J Neurol Neurosurg Psychiatry. 2013 Jan; 84(1):23-8. View in: PubMed

Li J, Jin Y, Shi Y, Dinov ID, Wang DJ, Toga AW, Thompson PM. Voxelwise spectral diffusional connectivity and its applications to Alzheimer's disease and intelligence prediction. Med Image Comput Comput Assist Interv. 2013; 16(Pt 1):655-62. View in: PubMed

Ajilore O, Zhan L, Gadelkarim J, Zhang A, Feusner JD, Yang S, Thompson PM, Kumar A, Leow A. Constructing the resting state structural connectome. Front Neuroinform. 2013; 7:30. View in: PubMed

Prestia A, Baglieri A, Pievani M, Bonetti M, Rasser PE, Thompson PM, Marino S, Bramanti P, Frisoni GB. The in vivo topography of cortical changes in healthy aging and prodromal Alzheimer's disease. Suppl Clin Neurophysiol. 2013; 62:67-80. View in: PubMed

Lutkenhoff ES, McArthur DL, Hua X, Thompson PM, Vespa PM, Monti MM. Thalamic atrophy in antero-medial and dorsal nuclei correlates with six-month outcome after severe brain injury. Neuroimage Clin. 2013; 3:396-404. View in: PubMed

Hegarty CE, Foland-Ross LC, Narr KL, Sugar CA, McGough JJ, Thompson PM, Altshuler LL. ADHD comorbidity can matter when assessing cortical thickness abnormalities in patients with bipolar disorder. Bipolar Disord. 2012 Dec; 14(8):843-55. View in: PubMed

Looi JC, Rajagopalan P, Walterfang M, Madsen SK, Thompson PM, Macfarlane MD, Ching C, Chua P, Velakoulis D. Differential putaminal morphology in Huntington's disease, frontotemporal dementia and Alzheimer's disease. Aust N Z J Psychiatry. 2012 Dec; 46(12):1145-58. View in: PubMed

Silver M, Janousova E, Hua X, Thompson PM, Montana G. Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression. Neuroimage. 2012 Nov 15; 63(3):1681-94. View in: PubMed

Ge T, Feng J, Hibar DP, Thompson PM, Nichols TE. Increasing power for voxel-wise genome-wide association studies: the random field theory, least square kernel machines and fast permutation procedures. Neuroimage. 2012 Nov 1; 63(2):858-73. View in: PubMed

Rudie JD, Hernandez LM, Brown JA, Beck-Pancer D, Colich NL, Gorrindo P, Thompson PM, Geschwind DH, Bookheimer SY, Levitt P, Dapretto M. Autism-Associated Promoter Variant in MET Impacts Functional and Structural Brain Networks. Neuron. 2012 Sep 6; 75(5):904-15. View in: PubMed

Yang Y, Nuechterlein KH, Phillips OR, Gutman B, Kurth F, Dinov I, Thompson PM, Asarnow RF, Toga AW, Narr KL. Disease and genetic contributions toward local tissue volume disturbances in schizophrenia: a tensor-based morphometry study. Hum Brain Mapp. 2012 Sep; 33(9):2081-91. View in: PubMed

Gogtay N, Hua X, Stidd R, Boyle CP, Lee S, Weisinger B, Chavez A, Giedd JN, Clasen L, Toga AW, Rapoport JL, Thompson PM. Delayed white matter growth trajectory in young nonpsychotic siblings of patients with childhood-onset schizophrenia. Arch Gen Psychiatry. 2012 Sep; 69(9):875-84. View in: PubMed

Liu F, van der Lijn F, Schurmann C, Zhu G, Chakravarty MM, Hysi PG, Wollstein A, Lao O, de Bruijne M, Ikram MA, van der Lugt A, Rivadeneira F, Uitterlinden AG, Hofman A, Niessen WJ, Homuth G, de Zubicaray G, McMahon KL, Thompson PM, Daboul A, Puls R, Hegenscheid K, Bevan L, Pausova Z, Medland SE, Montgomery GW, Wright MJ, Wicking C, Boehringer S, Spector TD, Paus T, Martin NG, Biffar R, Kayser M. A genome-wide association study identifies five loci influencing facial morphology in Europeans. PLoS Genet. 2012 Sep; 8(9):e1002932. View in: PubMed

Apostolova L, Alves G, Hwang KS, Babakchanian S, Bronnick KS, Larsen JP, Thompson PM, Chou YY, Tysnes OB, Vefring HK, Beyer MK. Hippocampal and ventricular changes in Parkinson's disease mild cognitive impairment. Neurobiol Aging. 2012 Sep; 33(9):2113-24. View in: PubMed

Braskie MN, Jahanshad N, Toga AW, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Thompson PM. How a common variant in the growth factor receptor gene, NTRK1, affects white matter. Bioarchitecture. 2012 Sep 1; 2(5):181-4. View in: PubMed

Yang Y, Joshi AA, Joshi SH, Baker LA, Narr KL, Raine A, Thompson PM, Damasio H. Genetic and environmental influences on cortical thickness among 14-year-old twins. Neuroreport. 2012 Aug 22; 23(12):702-6. View in: PubMed

Kohannim O, Jahanshad N, Braskie MN, Stein JL, Chiang MC, Reese AH, Hibar DP, Toga AW, McMahon KL, de Zubicaray GI, Medland SE, Montgomery GW, Martin NG, Wright MJ, Thompson PM. Predicting white matter integrity from multiple common genetic variants. Neuropsychopharmacology. 2012 Aug; 37(9):2012-9. View in: PubMed

Foland-Ross LC, Brooks JO, Mintz J, Bartzokis G, Townsend J, Thompson PM, Altshuler LL. Mood-state effects on amygdala volume in bipolar disorder. J Affect Disord. 2012 Aug; 139(3):298-301. View in: PubMed

Lutkenhoff E, Karlsgodt KH, Gutman B, Stein JL, Thompson PM, Cannon TD, Jentsch JD. Structural and functional neuroimaging phenotypes in dysbindin mutant mice. Neuroimage. 2012 Aug 1; 62(1):120-9. View in: PubMed

Nakamoto BK, Jahanshad N, McMurtray A, Kallianpur KJ, Chow DC, Valcour VG, Paul RH, Marotz L, Thompson PM, Shikuma CM. Cerebrovascular risk factors and brain microstructural abnormalities on diffusion tensor images in HIV-infected individuals. J Neurovirol. 2012 Aug; 18(4):303-12. View in: PubMed

Rossi R, Lanfredi M, Pievani M, Boccardi M, Beneduce R, Rillosi L, Giannakopoulos P, Thompson PM, Rossi G, Frisoni GB. Volumetric and topographic differences in hippocampal subdivisions in borderline personality and bipolar disorders. Psychiatry Res. 2012 Aug-Sep; 203(2-3):132-8. View in: PubMed

Protas HD, Kepe V, Hayashi KM, Klunder AD, Braskie MN, Ercoli L, Siddarth P, Bookheimer SY, Thompson PM, Small GW, Barrio JR, Huang SC. Prediction of cognitive decline based on hemispheric cortical surface maps of FDDNP PET. Neuroimage. 2012 Jul 16; 61(4):749-60. View in: PubMed

Yuan L, Wang Y, Thompson PM, Narayan VA, Ye J. Multi-source feature learning for joint analysis of incomplete multiple heterogeneous neuroimaging data. Neuroimage. 2012 Jul 2; 61(3):622-32. View in: PubMed

Toga AW, Clark KA, Thompson PM, Shattuck DW, Van Horn JD. Mapping the human connectome. Neurosurgery. 2012 Jul; 71(1):1-5. View in: PubMed

Chiang MC, Barysheva M, McMahon KL, de Zubicaray GI, Johnson K, Montgomery GW, Martin NG, Toga AW, Wright MJ, Shapshak P, Thompson PM. Gene network effects on brain microstructure and intellectual performance identified in 472 twins. J Neurosci. 2012 Jun 20; 32(25):8732-45. View in: PubMed

Thompson PM, Jahanshad N. Ironing out neurodegeneration: is iron intake important during the teenage years? Expert Rev Neurother. 2012 Jun; 12(6):629-31. View in: PubMed

Novak NM, Stein JL, Medland SE, Hibar DP, Thompson PM, Toga AW. EnigmaVis: online interactive visualization of genome-wide association studies of the Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium. Twin Res Hum Genet. 2012 Jun; 15(3):414-8. View in: PubMed

Hibar DP, Jahanshad N, Stein JL, Kohannim O, Toga AW, Medland SE, Hansell NK, McMahon KL, de Zubicaray GI, Montgomery GW, Martin NG, Wright MJ, Thompson PM. Alzheimer's disease risk gene, GAB2, is associated with regional brain volume differences in 755 young healthy twins. Twin Res Hum Genet. 2012 Jun; 15(3):286-95. View in: PubMed

Hegarty CE, Foland-Ross LC, Narr KL, Townsend JD, Bookheimer SY, Thompson PM, Altshuler LL. Anterior cingulate activation relates to local cortical thickness. Neuroreport. 2012 May 9; 23(7):420-4. View in: PubMed

Lee GJ, Lu PH, Hua X, Lee S, Wu S, Nguyen K, Teng E, Leow AD, Jack CR, Toga AW, Weiner MW, Bartzokis G, Thompson PM. Depressive symptoms in mild cognitive impairment predict greater atrophy in Alzheimer's disease-related regions. Biol Psychiatry. 2012 May 1; 71(9):814-21. View in: PubMed

Andrawis JP, Hwang KS, Green AE, Kotlerman J, Elashoff D, Morra JH, Cummings JL, Toga AW, Thompson PM, Apostolova LG. Effects of ApoE4 and maternal history of dementia on hippocampal atrophy. Neurobiol Aging. 2012 May; 33(5):856-66. View in: PubMed

Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 May; 44(5):545-51. View in: PubMed

Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth E, Lourdusamy A, Mattingsdal M, Mohnke S, Maniega SM, Nho K, Nugent AC, O'Brien C, Papmeyer M, Pütz B, Ramasamy A, Rasmussen J, Rijpkema M, Risacher SL, Roddey JC, Rose EJ, Ryten M, Shen L, Sprooten E, Strengman E, Teumer A, Trabzuni D, Turner J, van Eijk K, van Erp TG, van Tol MJ, Wittfeld K, Wolf C, Woudstra S, Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn DG, Cantor RM, Carless MA, Corvin A, Czisch M, Curran JE, Davies G, de Almeida MA, Delanty N, Depondt C, Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, Göring HH, Hagler DJ, Hoehn D, Holsboer F, Hoogman M, Hosten N, Jahanshad N, Johnson MP, Kasperaviciute D, Kent JW, Kochunov P, Lancaster JL, Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, Meisenzahl E, Melle I, Moses EK, Mühleisen TW, Nauck M, Nöthen MM, Olvera RL, Pandolfo M, Pike GB, Puls R, Reinvang I, Rentería ME, Rietschel M, Roffman JL, Royle NA, Rujescu D, Savitz J, Schnack HG, Schnell K, Seiferth N, Smith C, Steen VM, Valdés Hernández MC, Van den Heuvel M, van der Wee NJ, Van Haren NE, Veltman JA, Völzke H, Walker R, Westlye LT, Whelan CD, Agartz I, Boomsma DI, Cavalleri GL, Dale AM, Djurovic S, Drevets WC, Hagoort P, Hall J, Heinz A, Jack CR, Foroud TM, Le Hellard S, Macciardi F, Montgomery GW, Poline JB, Porteous DJ, Sisodiya SM, Starr JM, Sussmann J, Toga AW, Veltman DJ, Walter H, Weiner MW. Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet. 2012 May; 44(5):552-61. View in: PubMed

Braskie MN, Jahanshad N, Stein JL, Barysheva M, Johnson K, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Ringman JM, Toga AW, Thompson PM. Relationship of a variant in the NTRK1 gene to white matter microstructure in young adults. J Neurosci. 2012 Apr 25; 32(17):5964-72. View in: PubMed

Jahanshad N, Kohannim O, Hibar DP, Stein JL, McMahon KL, de Zubicaray GI, Medland SE, Montgomery GW, Whitfield JB, Martin NG, Wright MJ, Toga AW, Thompson PM. Brain structure in healthy adults is related to serum transferrin and the H63D polymorphism in the HFE gene. Proc Natl Acad Sci U S A. 2012 Apr 3; 109(14):E851-9. View in: PubMed

Cohen M, Rasser PE, Peck G, Carr VJ, Ward PB, Thompson PM, Johnston P, Baker A, Schall U. Cerebellar grey-matter deficits, cannabis use and first-episode schizophrenia in adolescents and young adults. Int J Neuropsychopharmacol. 2012 Apr; 15(3):297-307. View in: PubMed

Raji CA, Lopez OL, Kuller LH, Carmichael OT, Longstreth WT, Gach HM, Boardman J, Bernick CB, Thompson PM, Becker JT. White matter lesions and brain gray matter volume in cognitively normal elders. Neurobiol Aging. 2012 Apr; 33(4):834. e7-16. View in: PubMed

Vounou M, Janousova E, Wolz R, Stein JL, Thompson PM, Rueckert D, Montana G. Sparse reduced-rank regression detects genetic associations with voxel-wise longitudinal phenotypes in Alzheimer's disease. Neuroimage. 2012 Mar; 60(1):700-16. View in: PubMed

van Erp TG, Thompson PM, Kieseppä T, Bearden CE, Marino AC, Hoftman GD, Haukka J, Partonen T, Huttunen M, Kaprio J, Lönnqvist J, Poutanen VP, Toga AW, Cannon TD. Hippocampal morphology in lithium and non-lithium-treated bipolar I disorder patients, non-bipolar co-twins, and control twins. Hum Brain Mapp. 2012 Mar; 33(3):501-10. View in: PubMed

Toga AW, Dinov ID, Thompson PM, Woods RP, Van Horn JD, Shattuck DW, Parker DS. The Center for Computational Biology: resources, achievements, and challenges. J Am Med Inform Assoc. 2012 Mar-Apr; 19(2):202-6. View in: PubMed

Colby JB, Soderberg L, Lebel C, Dinov ID, Thompson PM, Sowell ER. Along-tract statistics allow for enhanced tractography analysis. Neuroimage. 2012 Feb 15; 59(4):3227-42. View in: PubMed

Duarte-Carvajalino JM, Jahanshad N, Lenglet C, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Thompson PM, Sapiro G. Hierarchical topological network analysis of anatomical human brain connectivity and differences related to sex and kinship. Neuroimage. 2012 Feb 15; 59(4):3784-804. View in: PubMed

Wang Y, Shi J, Yin X, Gu X, Chan TF, Yau ST, Toga AW, Thompson PM. Brain surface conformal parameterization with the Ricci flow. IEEE Trans Med Imaging. 2012 Feb; 31(2):251-64. View in: PubMed

Foland-Ross LC, Bookheimer SY, Lieberman MD, Sugar CA, Townsend JD, Fischer J, Torrisi S, Penfold C, Madsen SK, Thompson PM, Altshuler LL. Normal amygdala activation but deficient ventrolateral prefrontal activation in adults with bipolar disorder during euthymia. Neuroimage. 2012 Jan 2; 59(1):738-44. View in: PubMed

Dennis EL, Jahanshad N, Toga AW, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Thompson PM. Test-retest reliability of graph theory measures of structural brain connectivity. Med Image Comput Comput Assist Interv. 2012; 15(Pt 3):305-12. View in: PubMed

Engel J, Thompson PM. Going beyond hippocampocentricity in the concept of mesial temporal lobe epilepsy. Epilepsia. 2012 Jan; 53(1):220-3. View in: PubMed

Kohannim O, Hibar DP, Stein JL, Jahanshad N, Hua X, Rajagopalan P, Toga AW, Jack CR, Weiner MW, de Zubicaray GI, McMahon KL, Hansell NK, Martin NG, Wright MJ, Thompson PM. Discovery and Replication of Gene Influences on Brain Structure Using LASSO Regression. Front Neurosci. 2012; 6:115. View in: PubMed

Chow N, Aarsland D, Honarpisheh H, Beyer MK, Somme JH, Elashoff D, Rongve A, Tysnes OB, Thompson PM, Apostolova LG. Comparing hippocampal atrophy in Alzheimer's dementia and dementia with lewy bodies. Dement Geriatr Cogn Disord. 2012; 34(1):44-50. View in: PubMed

Rajagopalan P, Jahanshad N, Stein JL, Hua X, Madsen SK, Kohannim O, Hibar DP, Toga AW, Jack CR, Saykin AJ, Green RC, Weiner MW, Bis JC, Kuller LH, Riverol M, Becker JT, Lopez OL, Thompson PM. Common folate gene variant, MTHFR C677T, is associated with brain structure in two independent cohorts of people with mild cognitive impairment. Neuroimage Clin. 2012; 1(1):179-87. View in: PubMed

Leow AD, Zhan L, Arienzo D, GadElkarim JJ, Zhang AF, Ajilore O, Kumar A, Thompson PM, Feusner JD. Hierarchical structural mapping for globally optimized estimation of functional networks. Med Image Comput Comput Assist Interv. 2012; 15(Pt 2):228-36. View in: PubMed

Apostolova LG, Green AE, Babakchanian S, Hwang KS, Chou YY, Toga AW, Thompson PM. Hippocampal atrophy and ventricular enlargement in normal aging, mild cognitive impairment (MCI), and Alzheimer Disease. Alzheimer Dis Assoc Disord. 2012 Jan-Mar; 26(1):17-27. View in: PubMed

GadElkarim JJ, Schonfeld D, Ajilore O, Zhan L, Zhang AF, Feusner JD, Thompson PM, Simon TJ, Kumar A, Leow AD. A framework for quantifying node-level community structure group differences in brain connectivity networks. Med Image Comput Comput Assist Interv. 2012; 15(Pt 2):196-203. View in: PubMed

Thompson PM, Vinters HV. Pathologic lesions in neurodegenerative diseases. Prog Mol Biol Transl Sci. 2012; 107:1-40. View in: PubMed

Jahanshad N, Valcour VG, Nir TM, Kohannim O, Busovaca E, Nicolas K, Thompson PM. Disrupted brain networks in the aging HIV+ population. Brain Connect. 2012; 2(6):335-44. View in: PubMed

Iglesias JE, Thompson PM, Liu CY, Tu Z. Fast approximate stochastic tractography. Neuroinformatics. 2012 Jan; 10(1):5-17. View in: PubMed

Ewers M, Frisoni GB, Teipel SJ, Grinberg LT, Amaro E, Heinsen H, Thompson PM, Hampel H. Staging Alzheimer's disease progression with multimodality neuroimaging. Prog Neurobiol. 2011 Dec; 95(4):535-46. View in: PubMed

Lu PH, Lee GJ, Raven EP, Tingus K, Khoo T, Thompson PM, Bartzokis G. Age-related slowing in cognitive processing speed is associated with myelin integrity in a very healthy elderly sample. J Clin Exp Neuropsychol. 2011 Dec; 33(10):1059-68. View in: PubMed

den Braber A, van 't Ent D, Boomsma DI, Cath DC, Veltman DJ, Thompson PM, de Geus EJ. White matter differences in monozygotic twins discordant or concordant for obsessive-compulsive symptoms: a combined diffusion tensor imaging/voxel-based morphometry study. Biol Psychiatry. 2011 Nov 15; 70(10):969-77. View in: PubMed

Bearden CE, van Erp TG, Dutton RA, Boyle C, Madsen S, Luders E, Kieseppa T, Tuulio-Henriksson A, Huttunen M, Partonen T, Kaprio J, Lönnqvist J, Thompson PM, Cannon TD. Mapping corpus callosum morphology in twin pairs discordant for bipolar disorder. Cereb Cortex. 2011 Oct; 21(10):2415-24. View in: PubMed

Ho AJ, Raji CA, Becker JT, Lopez OL, Kuller LH, Hua X, Dinov ID, Stein JL, Rosano C, Toga AW, Thompson PM. The effects of physical activity, education, and body mass index on the aging brain. Hum Brain Mapp. 2011 Sep; 32(9):1371-82. View in: PubMed

Chiang GC, Insel PS, Tosun D, Schuff N, Truran-Sacrey D, Raptentsetsang ST, Thompson PM, Reiman EM, Jack CR, Fox NC, Jagust WJ, Harvey DJ, Beckett LA, Gamst A, Aisen PS, Petersen RC, Weiner MW. Impact of apolipoprotein E4-cerebrospinal fluid ß-amyloid interaction on hippocampal volume loss over 1 year in mild cognitive impairment. Alzheimers Dement. 2011 Sep; 7(5):514-20. View in: PubMed

Iglesias JE, Liu CY, Thompson PM, Tu Z. Robust brain extraction across datasets and comparison with publicly available methods. IEEE Trans Med Imaging. 2011 Sep; 30(9):1617-34. View in: PubMed

Boccardi M, Frisoni GB, Hare RD, Cavedo E, Najt P, Pievani M, Rasser PE, Laakso MP, Aronen HJ, Repo-Tiihonen E, Vaurio O, Thompson PM, Tiihonen J. Cortex and amygdala morphology in psychopathy. Psychiatry Res. 2011 Aug 30; 193(2):85-92. View in: PubMed

Aganj I, Lenglet C, Jahanshad N, Yacoub E, Harel N, Thompson PM, Sapiro G. A Hough transform global probabilistic approach to multiple-subject diffusion MRI tractography. Med Image Anal. 2011 Aug; 15(4):414-25. View in: PubMed

Welcome SE, Chiarello C, Thompson PM, Sowell ER. Reading skill is related to individual differences in brain structure in college students. Hum Brain Mapp. 2011 Aug; 32(8):1194-205. View in: PubMed

Brooks JO, Foland-Ross LC, Thompson PM, Altshuler LL. Preliminary evidence of within-subject changes in gray matter density associated with remission of bipolar depression. Psychiatry Res. 2011 Jul 30; 193(1):53-5. View in: PubMed

Blokland GA, McMahon KL, Thompson PM, Martin NG, de Zubicaray GI, Wright MJ. Heritability of working memory brain activation. J Neurosci. 2011 Jul 27; 31(30):10882-90. View in: PubMed

Yotter RA, Dahnke R, Thompson PM, Gaser C. Topological correction of brain surface meshes using spherical harmonics. Hum Brain Mapp. 2011 Jul; 32(7):1109-24. View in: PubMed

Hua X, Gutman B, Boyle CP, Rajagopalan P, Leow AD, Yanovsky I, Kumar AR, Toga AW, Jack CR, Schuff N, Alexander GE, Chen K, Reiman EM, Weiner MW, Thompson PM. Accurate measurement of brain changes in longitudinal MRI scans using tensor-based morphometry. Neuroimage. 2011 Jul 1; 57(1):5-14. View in: PubMed

Jack CR, Barkhof F, Bernstein MA, Cantillon M, Cole PE, Decarli C, Dubois B, Duchesne S, Fox NC, Frisoni GB, Hampel H, Hill DL, Johnson K, Mangin JF, Scheltens P, Schwarz AJ, Sperling R, Suhy J, Thompson PM, Weiner M, Foster NL. Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease. Alzheimers Dement. 2011 Jul; 7(4):474-485. e4. View in: PubMed

Gonzalez JE, Thompson PM, Zhao A, Tu Z. Modeling diffusion-weighted MRI as a spatially variant gaussian mixture: application to image denoising. Med Phys. 2011 Jul; 38(7):4350-64. View in: PubMed

Wang Y, Song Y, Rajagopalan P, An T, Liu K, Chou YY, Gutman B, Toga AW, Thompson PM. Surface-based TBM boosts power to detect disease effects on the brain: an N=804 ADNI study. Neuroimage. 2011 Jun 15; 56(4):1993-2010. View in: PubMed

Hibar DP, Stein JL, Kohannim O, Jahanshad N, Saykin AJ, Shen L, Kim S, Pankratz N, Foroud T, Huentelman MJ, Potkin SG, Jack CR, Weiner MW, Toga AW, Thompson PM. Voxelwise gene-wide association study (vGeneWAS): multivariate gene-based association testing in 731 elderly subjects. Neuroimage. 2011 Jun 15; 56(4):1875-91. View in: PubMed

Rajagopalan P, Hua X, Toga AW, Jack CR, Weiner MW, Thompson PM. Homocysteine effects on brain volumes mapped in 732 elderly individuals. Neuroreport. 2011 Jun 11; 22(8):391-5. View in: PubMed

Goh A, Lenglet C, Thompson PM, Vidal R. A nonparametric Riemannian framework for processing high angular resolution diffusion images and its applications to ODF-based morphometry. Neuroimage. 2011 Jun 1; 56(3):1181-201. View in: PubMed

Yotter RA, Nenadic I, Ziegler G, Thompson PM, Gaser C. Local cortical surface complexity maps from spherical harmonic reconstructions. Neuroimage. 2011 Jun 1; 56(3):961-73. View in: PubMed

Becker JT, Sanders J, Madsen SK, Ragin A, Kingsley L, Maruca V, Cohen B, Goodkin K, Martin E, Miller EN, Sacktor N, Alger JR, Barker PB, Saharan P, Carmichael OT, Thompson PM. Subcortical brain atrophy persists even in HAART-regulated HIV disease. Brain Imaging Behav. 2011 Jun; 5(2):77-85. View in: PubMed

Frisoni GB, Prestia A, Geroldi C, Adorni A, Ghidoni R, Amicucci G, Bonetti M, Soricelli A, Rasser PE, Thompson PM, Giannakopoulos P. Alzheimer's CSF markers in older schizophrenia patients. Int J Geriatr Psychiatry. 2011 Jun; 26(6):640-8. View in: PubMed

Kumar R, Nguyen HD, Ogren JA, Macey PM, Thompson PM, Fonarow GC, Hamilton MA, Harper RM, Woo MA. Global and regional putamen volume loss in patients with heart failure. Eur J Heart Fail. 2011 Jun; 13(6):651-5. View in: PubMed

Braskie MN, Jahanshad N, Stein JL, Barysheva M, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Ringman JM, Toga AW, Thompson PM. Common Alzheimer's disease risk variant within the CLU gene affects white matter microstructure in young adults. J Neurosci. 2011 May 4; 31(18):6764-70. View in: PubMed

Westerhausen R, Luders E, Specht K, Ofte SH, Toga AW, Thompson PM, Helland T, Hugdahl K. Structural and functional reorganization of the corpus callosum between the age of 6 and 8 years. Cereb Cortex. 2011 May; 21(5):1012-7. View in: PubMed

Chen K, Ayutyanont N, Langbaum JB, Fleisher AS, Reschke C, Lee W, Liu X, Bandy D, Alexander GE, Thompson PM, Shaw L, Trojanowski JQ, Jack CR, Landau SM, Foster NL, Harvey DJ, Weiner MW, Koeppe RA, Jagust WJ, Reiman EM. Characterizing Alzheimer's disease using a hypometabolic convergence index. Neuroimage. 2011 May 1; 56(1):52-60. View in: PubMed

Foland-Ross LC, Thompson PM, Sugar CA, Madsen SK, Shen JK, Penfold C, Ahlf K, Rasser PE, Fischer J, Yang Y, Townsend J, Bookheimer SY, Altshuler LL. Investigation of cortical thickness abnormalities in lithium-free adults with bipolar I disorder using cortical pattern matching. Am J Psychiatry. 2011 May; 168(5):530-9. View in: PubMed

Yotter RA, Thompson PM, Gaser C. Algorithms to improve the reparameterization of spherical mappings of brain surface meshes. J Neuroimaging. 2011 Apr; 21(2):e134-47. View in: PubMed

Pievani M, Galluzzi S, Thompson PM, Rasser PE, Bonetti M, Frisoni GB. APOE4 is associated with greater atrophy of the hippocampal formation in Alzheimer's disease. Neuroimage. 2011 Apr 1; 55(3):909-19. View in: PubMed

Scher AI, Xu Y, Korf ES, Hartley SW, Witter MP, Scheltens P, White LR, Thompson PM, Toga AW, Valentino DJ, Launer LJ. Hippocampal morphometry in population-based incident Alzheimer's disease and vascular dementia: the HAAS. J Neurol Neurosurg Psychiatry. 2011 Apr; 82(4):373-6. View in: PubMed

Finegersh A, Avedissian C, Shamim S, Dustin I, Thompson PM, Theodore WH. Bilateral hippocampal atrophy in temporal lobe epilepsy: effect of depressive symptoms and febrile seizures. Epilepsia. 2011 Apr; 52(4):689-97. View in: PubMed

Chiang MC, Barysheva M, Toga AW, Medland SE, Hansell NK, James MR, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Thompson PM. BDNF gene effects on brain circuitry replicated in 455 twins. Neuroimage. 2011 Mar 15; 55(2):448-54. View in: PubMed

Thomason ME, Dennis EL, Joshi AA, Joshi SH, Dinov ID, Chang C, Henry ML, Johnson RF, Thompson PM, Toga AW, Glover GH, Van Horn JD, Gotlib IH. Resting-state fMRI can reliably map neural networks in children. Neuroimage. 2011 Mar 1; 55(1):165-75. View in: PubMed

Joshi AA, Leporé N, Joshi SH, Lee AD, Barysheva M, Stein JL, McMahon KL, Johnson K, de Zubicaray GI, Martin NG, Wright MJ, Toga AW, Thompson PM. The contribution of genes to cortical thickness and volume. Neuroreport. 2011 Feb 16; 22(3):101-5. View in: PubMed

Brun CC, Lepore N, Pennec X, Chou YY, Lee AD, de Zubicaray G, McMahon KL, Wright MJ, Gee JC, Thompson PM. A nonconservative Lagrangian framework for statistical fluid registration-SAFIRA. IEEE Trans Med Imaging. 2011 Feb; 30(2):184-202. View in: PubMed

Chiang MC, McMahon KL, de Zubicaray GI, Martin NG, Hickie I, Toga AW, Wright MJ, Thompson PM. Genetics of white matter development: a DTI study of 705 twins and their siblings aged 12 to 29. Neuroimage. 2011 Feb 1; 54(3):2308-17. View in: PubMed

Luders E, Thompson PM, Narr KL, Zamanyan A, Chou YY, Gutman B, Dinov ID, Toga AW. The link between callosal thickness and intelligence in healthy children and adolescents. Neuroimage. 2011 Feb 1; 54(3):1823-30. View in: PubMed

Ho AJ, Raji CA, Saharan P, DeGiorgio A, Madsen SK, Hibar DP, Stein JL, Becker JT, Lopez OL, Toga AW, Thompson PM. Hippocampal volume is related to body mass index in Alzheimer's disease. Neuroreport. 2011 Jan 5; 22(1):10-4. View in: PubMed

Braskie MN, Ringman JM, Thompson PM. Neuroimaging measures as endophenotypes in Alzheimer's disease. Int J Alzheimers Dis. 2011; 2011:490140. View in: PubMed

Lu PH, Thompson PM, Leow A, Lee GJ, Lee A, Yanovsky I, Parikshak N, Khoo T, Wu S, Geschwind D, Bartzokis G. Apolipoprotein E genotype is associated with temporal and hippocampal atrophy rates in healthy elderly adults: a tensor-based morphometry study. J Alzheimers Dis. 2011; 23(3):433-42. View in: PubMed

Hibar DP, Kohannim O, Stein JL, Chiang MC, Thompson PM. Multilocus genetic analysis of brain images. Front Genet. 2011; 2:73. View in: PubMed

Kochunov P, Glahn DC, Nichols TE, Winkler AM, Hong EL, Holcomb HH, Stein JL, Thompson PM, Curran JE, Carless MA, Olvera RL, Johnson MP, Cole SA, Kochunov V, Kent J, Blangero J. Genetic analysis of cortical thickness and fractional anisotropy of water diffusion in the brain. Front Neurosci. 2011; 5:120. View in: PubMed

Apostolova LG, Hwang KS, Medina LD, Green AE, Braskie MN, Dutton RA, Lai J, Geschwind DH, Cummings JL, Thompson PM, Ringman JM. Cortical and hippocampal atrophy in patients with autosomal dominant familial Alzheimer's disease. Dement Geriatr Cogn Disord. 2011; 32(2):118-25. View in: PubMed

Dennis EL, Jahanshad N, Rudie JD, Brown JA, Johnson K, McMahon KL, de Zubicaray GI, Montgomery G, Martin NG, Wright MJ, Bookheimer SY, Dapretto M, Toga AW, Thompson PM. Altered structural brain connectivity in healthy carriers of the autism risk gene, CNTNAP2. Brain Connect. 2011; 1(6):447-59. View in: PubMed

Dennis EL, Gotlib IH, Thompson PM, Thomason ME. Anxiety modulates insula recruitment in resting-state functional magnetic resonance imaging in youth and adults. Brain Connect. 2011; 1(3):245-54. View in: PubMed

Thomason ME, Thompson PM. Diffusion imaging, white matter, and psychopathology. Annu Rev Clin Psychol. 2011; 7:63-85. View in: PubMed

Foland-Ross LC, Altshuler LL, Bookheimer SY, Lieberman MD, Townsend J, Penfold C, Moody T, Ahlf K, Shen JK, Madsen SK, Rasser PE, Toga AW, Thompson PM. Amygdala reactivity in healthy adults is correlated with prefrontal cortical thickness. J Neurosci. 2010 Dec 8; 30(49):16673-8. View in: PubMed

Rasser PE, Schall U, Peck G, Cohen M, Johnston P, Khoo K, Carr VJ, Ward PB, Thompson PM. Cerebellar grey matter deficits in first-episode schizophrenia mapped using cortical pattern matching. Neuroimage. 2010 Dec; 53(4):1175-80. View in: PubMed

Shi Y, Lai R, Morra JH, Dinov I, Thompson PM, Toga AW. Robust surface reconstruction via Laplace-Beltrami eigen-projection and boundary deformation. IEEE Trans Med Imaging. 2010 Dec; 29(12):2009-22. View in: PubMed

Minnerop M, Lüders E, Specht K, Ruhlmann J, Schimke N, Thompson PM, Chou YY, Toga AW, Abele M, Wüllner U, Klockgether T. Callosal tissue loss in multiple system atrophy--a one-year follow-up study. Mov Disord. 2010 Nov 15; 25(15):2613-20. View in: PubMed

Wu X, Chen K, Yao L, Ayutyanont N, Langbaum JB, Fleisher A, Reschke C, Lee W, Liu X, Alexander GE, Bandy D, Foster NL, Thompson PM, Harvey DJ, Weiner MW, Koeppe RA, Jagust WJ, Reiman EM. Assessing the reliability to detect cerebral hypometabolism in probable Alzheimer's disease and amnestic mild cognitive impairment. J Neurosci Methods. 2010 Oct 15; 192(2):277-85. View in: PubMed

Braskie MN, Klunder AD, Hayashi KM, Protas H, Kepe V, Miller KJ, Huang SC, Barrio JR, Ercoli LM, Siddarth P, Satyamurthy N, Liu J, Toga AW, Bookheimer SY, Small GW, Thompson PM. Plaque and tangle imaging and cognition in normal aging and Alzheimer's disease. Neurobiol Aging. 2010 Oct; 31(10):1669-78. View in: PubMed

Bartzokis G, Lu PH, Tingus K, Mendez MF, Richard A, Peters DG, Oluwadara B, Barrall KA, Finn JP, Villablanca P, Thompson PM, Mintz J. Lifespan trajectory of myelin integrity and maximum motor speed. Neurobiol Aging. 2010 Sep; 31(9):1554-62. View in: PubMed

Luders E, Thompson PM, Toga AW. The development of the corpus callosum in the healthy human brain. J Neurosci. 2010 Aug 18; 30(33):10985-90. View in: PubMed

Jahanshad N, Lee AD, Barysheva M, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Toga AW, Thompson PM. Genetic influences on brain asymmetry: a DTI study of 374 twins and siblings. Neuroimage. 2010 Aug 15; 52(2):455-69. View in: PubMed

Kohannim O, Hua X, Hibar DP, Lee S, Chou YY, Toga AW, Jack CR, Weiner MW, Thompson PM. Boosting power for clinical trials using classifiers based on multiple biomarkers. Neurobiol Aging. 2010 Aug; 31(8):1429-42. View in: PubMed

Apostolova LG, Hwang KS, Andrawis JP, Green AE, Babakchanian S, Morra JH, Cummings JL, Toga AW, Trojanowski JQ, Shaw LM, Jack CR, Petersen RC, Aisen PS, Jagust WJ, Koeppe RA, Mathis CA, Weiner MW, Thompson PM. 3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects. Neurobiol Aging. 2010 Aug; 31(8):1284-303. View in: PubMed

Chou YY, Leporé N, Saharan P, Madsen SK, Hua X, Jack CR, Shaw LM, Trojanowski JQ, Weiner MW, Toga AW, Thompson PM. Ventricular maps in 804 ADNI subjects: correlations with CSF biomarkers and clinical decline. Neurobiol Aging. 2010 Aug; 31(8):1386-400. View in: PubMed

Hua X, Hibar DP, Lee S, Toga AW, Jack CR, Weiner MW, Thompson PM. Sex and age differences in atrophic rates: an ADNI study with n=1368 MRI scans. Neurobiol Aging. 2010 Aug; 31(8):1463-80. View in: PubMed

Thompson PM, Martin NG, Wright MJ. Imaging genomics. Curr Opin Neurol. 2010 Aug; 23(4):368-73. View in: PubMed

Luders E, Cherbuin N, Thompson PM, Gutman B, Anstey KJ, Sachdev P, Toga AW. When more is less: associations between corpus callosum size and handedness lateralization. Neuroimage. 2010 Aug 1; 52(1):43-9. View in: PubMed

Ho AJ, Raji CA, Becker JT, Lopez OL, Kuller LH, Hua X, Lee S, Hibar D, Dinov ID, Stein JL, Jack CR, Weiner MW, Toga AW, Thompson PM. Obesity is linked with lower brain volume in 700 AD and MCI patients. Neurobiol Aging. 2010 Aug; 31(8):1326-39. View in: PubMed

Patel V, Shi Y, Thompson PM, Toga AW. Mesh-based spherical deconvolution: a flexible approach to reconstruction of non-negative fiber orientation distributions. Neuroimage. 2010 Jul 1; 51(3):1071-81. View in: PubMed

Apostolova LG, Mosconi L, Thompson PM, Green AE, Hwang KS, Ramirez A, Mistur R, Tsui WH, de Leon MJ. Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal. Neurobiol Aging. 2010 Jul; 31(7):1077-88. View in: PubMed

Leporé N, Vachon P, Lepore F, Chou YY, Voss P, Brun CC, Lee AD, Toga AW, Thompson PM. 3D mapping of brain differences in native signing congenitally and prelingually deaf subjects. Hum Brain Mapp. 2010 Jul; 31(7):970-8. View in: PubMed

Chen K, Langbaum JB, Fleisher AS, Ayutyanont N, Reschke C, Lee W, Liu X, Bandy D, Alexander GE, Thompson PM, Foster NL, Harvey DJ, de Leon MJ, Koeppe RA, Jagust WJ, Weiner MW, Reiman EM. Twelve-month metabolic declines in probable Alzheimer's disease and amnestic mild cognitive impairment assessed using an empirically pre-defined statistical region-of-interest: findings from the Alzheimer's Disease Neuroimaging Initiative. Neuroimage. 2010 Jun; 51(2):654-64. View in: PubMed

Patel V, Dinov ID, Van Horn JD, Thompson PM, Toga AW. LONI MiND: metadata in NIfTI for DWI. Neuroimage. 2010 Jun; 51(2):665-76. View in: PubMed

Stein JL, Hua X, Morra JH, Lee S, Hibar DP, Ho AJ, Leow AD, Toga AW, Sul JH, Kang HM, Eskin E, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, Allen AN, Corneveaux JJ, Stephan DA, Webster J, DeChairo BM, Potkin SG, Jack CR, Weiner MW, Thompson PM. Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease. Neuroimage. 2010 Jun; 51(2):542-54. View in: PubMed

Apostolova LG, Morra JH, Green AE, Hwang KS, Avedissian C, Woo E, Cummings JL, Toga AW, Jack CR, Weiner MW, Thompson PM. Automated 3D mapping of baseline and 12-month associations between three verbal memory measures and hippocampal atrophy in 490 ADNI subjects. Neuroimage. 2010 May 15; 51(1):488-99. View in: PubMed

Hua X, Lee S, Hibar DP, Yanovsky I, Leow AD, Toga AW, Jack CR, Bernstein MA, Reiman EM, Harvey DJ, Kornak J, Schuff N, Alexander GE, Weiner MW, Thompson PM. Mapping Alzheimer's disease progression in 1309 MRI scans: power estimates for different inter-scan intervals. Neuroimage. 2010 May 15; 51(1):63-75. View in: PubMed

Ho AJ, Stein JL, Hua X, Lee S, Hibar DP, Leow AD, Dinov ID, Toga AW, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, Allen AN, Corneveaux JJ, Stephan DA, DeCarli CS, DeChairo BM, Potkin SG, Jack CR, Weiner MW, Raji CA, Lopez OL, Becker JT, Carmichael OT, Thompson PM. A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proc Natl Acad Sci U S A. 2010 May 4; 107(18):8404-9. View in: PubMed

Saykin AJ, Shen L, Foroud TM, Potkin SG, Swaminathan S, Kim S, Risacher SL, Nho K, Huentelman MJ, Craig DW, Thompson PM, Stein JL, Moore JH, Farrer LA, Green RC, Bertram L, Jack CR, Weiner MW. Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans. Alzheimers Dement. 2010 May; 6(3):265-73. View in: PubMed

Jack CR, Bernstein MA, Borowski BJ, Gunter JL, Fox NC, Thompson PM, Schuff N, Krueger G, Killiany RJ, Decarli CS, Dale AM, Carmichael OW, Tosun D, Weiner MW. Update on the magnetic resonance imaging core of the Alzheimer's disease neuroimaging initiative. Alzheimers Dement. 2010 May; 6(3):212-20. View in: PubMed

Apostolova LG, Thompson PM, Green AE, Hwang KS, Zoumalan C, Jack CR, Harvey DJ, Petersen RC, Thal LJ, Aisen PS, Toga AW, Cummings JL, Decarli CS. 3D comparison of low, intermediate, and advanced hippocampal atrophy in MCI. Hum Brain Mapp. 2010 May; 31(5):786-97. View in: PubMed

Apostolova LG, Beyer M, Green AE, Hwang KS, Morra JH, Chou YY, Avedissian C, Aarsland D, Janvin CC, Larsen JP, Cummings JL, Thompson PM. Hippocampal, caudate, and ventricular changes in Parkinson's disease with and without dementia. Mov Disord. 2010 Apr 30; 25(6):687-95. View in: PubMed

Apostolova LG, Thompson PM, Rogers SA, Dinov ID, Zoumalan C, Steiner CA, Siu E, Green AE, Small GW, Toga AW, Cummings JL, Phelps ME, Silverman DH. Surface feature-guided mapping of cerebral metabolic changes in cognitively normal and mildly impaired elderly. Mol Imaging Biol. 2010 Apr; 12(2):218-24. View in: PubMed

Ho AJ, Hua X, Lee S, Leow AD, Yanovsky I, Gutman B, Dinov ID, Leporé N, Stein JL, Toga AW, Jack CR, Bernstein MA, Reiman EM, Harvey DJ, Kornak J, Schuff N, Alexander GE, Weiner MW, Thompson PM. Comparing 3 T and 1. 5 T MRI for tracking Alzheimer's disease progression with tensor-based morphometry. Hum Brain Mapp. 2010 Apr; 31(4):499-514. View in: PubMed

Sowell ER, Leow AD, Bookheimer SY, Smith LM, O'Connor MJ, Kan E, Rosso C, Houston S, Dinov ID, Thompson PM. Differentiating prenatal exposure to methamphetamine and alcohol versus alcohol and not methamphetamine using tensor-based brain morphometry and discriminant analysis. J Neurosci. 2010 Mar 17; 30(11):3876-85. View in: PubMed

Boccardi M, Ganzola R, Rossi R, Sabattoli F, Laakso MP, Repo-Tiihonen E, Vaurio O, Könönen M, Aronen HJ, Thompson PM, Frisoni GB, Tiihonen J. Abnormal hippocampal shape in offenders with psychopathy. Hum Brain Mapp. 2010 Mar; 31(3):438-47. View in: PubMed

Raji CA, Ho AJ, Parikshak NN, Becker JT, Lopez OL, Kuller LH, Hua X, Leow AD, Toga AW, Thompson PM. Brain structure and obesity. Hum Brain Mapp. 2010 Mar; 31(3):353-64. View in: PubMed

Gogtay N, Thompson PM. Mapping gray matter development: implications for typical development and vulnerability to psychopathology. Brain Cogn. 2010 Feb; 72(1):6-15. View in: PubMed

Engel J, Akhtari M, Bragin A, Fried I, Ogren JA, Staba RJ, Salamon N, Thompson PM. New approaches to structural and functional imaging in focal epilepsy. Epilepsia. 2010 Feb; 51 Suppl 1:83-6. View in: PubMed

Frisoni GB, Fox NC, Jack CR, Scheltens P, Thompson PM. The clinical use of structural MRI in Alzheimer disease. Nat Rev Neurol. 2010 Feb; 6(2):67-77. View in: PubMed

Wang Y, Zhang J, Gutman B, Chan TF, Becker JT, Aizenstein HJ, Lopez OL, Tamburo RJ, Toga AW, Thompson PM. Multivariate tensor-based morphometry on surfaces: application to mapping ventricular abnormalities in HIV/AIDS. Neuroimage. 2010 Feb 1; 49(3):2141-57. View in: PubMed

Zhan L, Leow AD, Jahanshad N, Chiang MC, Barysheva M, Lee AD, Toga AW, McMahon KL, de Zubicaray GI, Wright MJ, Thompson PM. How does angular resolution affect diffusion imaging measures? Neuroimage. 2010 Jan 15; 49(2):1357-71. View in: PubMed

Leporé N, Voss P, Lepore F, Chou YY, Fortin M, Gougoux F, Lee AD, Brun C, Lassonde M, Madsen SK, Toga AW, Thompson PM. Brain structure changes visualized in early- and late-onset blind subjects. Neuroimage. 2010 Jan 1; 49(1):134-40. View in: PubMed

Morra JH, Tu Z, Apostolova LG, Green AE, Toga AW, Thompson PM. Comparison of AdaBoost and support vector machines for detecting Alzheimer's disease through automated hippocampal segmentation. IEEE Trans Med Imaging. 2010 Jan; 29(1):30-43. View in: PubMed

Yotter RA, Thompson PM, Nenadic I, Gaser C. Estimating local surface complexity maps using spherical harmonic reconstructions. Med Image Comput Comput Assist Interv. 2010; 13(Pt 2):169-76. View in: PubMed

Prestia A, Drago V, Rasser PE, Bonetti M, Thompson PM, Frisoni GB. Cortical changes in incipient Alzheimer's disease. J Alzheimers Dis. 2010; 22(4):1339-49. View in: PubMed

Di Paola M, Luders E, Di Iulio F, Cherubini A, Passafiume D, Thompson PM, Caltagirone C, Toga AW, Spalletta G. Callosal atrophy in mild cognitive impairment and Alzheimer's disease: different effects in different stages. Neuroimage. 2010 Jan 1; 49(1):141-9. View in: PubMed

Brun CC, Nicolson R, Leporé N, Chou YY, Vidal CN, DeVito TJ, Drost DJ, Williamson PC, Rajakumar N, Toga AW, Thompson PM. Mapping brain abnormalities in boys with autism. Hum Brain Mapp. 2009 Dec; 30(12):3887-900. View in: PubMed

Sun D, van Erp TG, Thompson PM, Bearden CE, Daley M, Kushan L, Hardt ME, Nuechterlein KH, Toga AW, Cannon TD. Elucidating a magnetic resonance imaging-based neuroanatomic biomarker for psychosis: classification analysis using probabilistic brain atlas and machine learning algorithms. Biol Psychiatry. 2009 Dec 1; 66(11):1055-60. View in: PubMed

Hua X, Lee S, Yanovsky I, Leow AD, Chou YY, Ho AJ, Gutman B, Toga AW, Jack CR, Bernstein MA, Reiman EM, Harvey DJ, Kornak J, Schuff N, Alexander GE, Weiner MW, Thompson PM. Optimizing power to track brain degeneration in Alzheimer's disease and mild cognitive impairment with tensor-based morphometry: an ADNI study of 515 subjects. Neuroimage. 2009 Dec; 48(4):668-81. View in: PubMed

Ogren JA, Wilson CL, Bragin A, Lin JJ, Salamon N, Dutton RA, Luders E, Fields TA, Fried I, Toga AW, Thompson PM, Engel J, Staba RJ. Three-dimensional surface maps link local atrophy and fast ripples in human epileptic hippocampus. Ann Neurol. 2009 Dec; 66(6):783-91. View in: PubMed

Lu LH, Dapretto M, O'Hare ED, Kan E, McCourt ST, Thompson PM, Toga AW, Bookheimer SY, Sowell ER. Relationships between brain activation and brain structure in normally developing children. Cereb Cortex. 2009 Nov; 19(11):2595-604. View in: PubMed

Narr KL, Szeszko PR, Lencz T, Woods RP, Hamilton LS, Phillips O, Robinson D, Burdick KE, DeRosse P, Kucherlapati R, Thompson PM, Toga AW, Malhotra AK, Bilder RM. DTNBP1 is associated with imaging phenotypes in schizophrenia. Hum Brain Mapp. 2009 Nov; 30(11):3783-94. View in: PubMed

Brun CC, Leporé N, Pennec X, Lee AD, Barysheva M, Madsen SK, Avedissian C, Chou YY, de Zubicaray GI, McMahon KL, Wright MJ, Toga AW, Thompson PM. Mapping the regional influence of genetics on brain structure variability--a tensor-based morphometry study. Neuroimage. 2009 Oct 15; 48(1):37-49. View in: PubMed

Aganj I, Sapiro G, Parikshak N, Madsen SK, Thompson PM. Measurement of cortical thickness from MRI by minimum line integrals on soft-classified tissue. Hum Brain Mapp. 2009 Oct; 30(10):3188-99. View in: PubMed

Yanovsky I, Leow AD, Lee S, Osher SJ, Thompson PM. Comparing registration methods for mapping brain change using tensor-based morphometry. Med Image Anal. 2009 Oct; 13(5):679-700. View in: PubMed

Frisoni GB, Prestia A, Adorni A, Rasser PE, Cotelli M, Soricelli A, Bonetti M, Geroldi C, Giannakopoulos P, Thompson PM. In vivo neuropathology of cortical changes in elderly persons with schizophrenia. Biol Psychiatry. 2009 Sep 15; 66(6):578-85. View in: PubMed

Morra JH, Tu Z, Apostolova LG, Green AE, Avedissian C, Madsen SK, Parikshak N, Hua X, Toga AW, Jack CR, Schuff N, Weiner MW, Thompson PM. Automated 3D mapping of hippocampal atrophy and its clinical correlates in 400 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls. Hum Brain Mapp. 2009 Sep; 30(9):2766-88. View in: PubMed

Freitag CM, Luders E, Hulst HE, Narr KL, Thompson PM, Toga AW, Krick C, Konrad C. Total brain volume and corpus callosum size in medication-naïve adolescents and young adults with autism spectrum disorder. Biol Psychiatry. 2009 Aug 15; 66(4):316-9. View in: PubMed

Eckstein I, Shattuck DW, Stein JL, McMahon KL, de Zubicaray G, Wright MJ, Thompson PM, Toga AW. Active fibers: matching deformable tract templates to diffusion tensor images. Neuroimage. 2009 Aug; 47 Suppl 2:T82-9. View in: PubMed

Leporé N, Shi Y, Lepore F, Fortin M, Voss P, Chou YY, Lord C, Lassonde M, Dinov ID, Toga AW, Thompson PM. Pattern of hippocampal shape and volume differences in blind subjects. Neuroimage. 2009 Jul 15; 46(4):949-57. View in: PubMed

Brun CC, Leporé N, Luders E, Chou YY, Madsen SK, Toga AW, Thompson PM. Sex differences in brain structure in auditory and cingulate regions. Neuroreport. 2009 Jul 1; 20(10):930-5. View in: PubMed

Frisoni GB, Prestia A, Rasser PE, Bonetti M, Thompson PM. In vivo mapping of incremental cortical atrophy from incipient to overt Alzheimer's disease. J Neurol. 2009 Jun; 256(6):916-24. View in: PubMed

Gutman B, Wang Y, Morra J, Toga AW, Thompson PM. Disease classification with hippocampal shape invariants. Hippocampus. 2009 Jun; 19(6):572-8. View in: PubMed

Ogren JA, Bragin A, Wilson CL, Hoftman GD, Lin JJ, Dutton RA, Fields TA, Toga AW, Thompson PM, Engel J, Staba RJ. Three-dimensional hippocampal atrophy maps distinguish two common temporal lobe seizure-onset patterns. Epilepsia. 2009 Jun; 50(6):1361-70. View in: PubMed

Joshi AA, Shattuck DW, Thompson PM, Leahy RM. A parameterization-based numerical method for isotropic and anisotropic diffusion smoothing on non-flat surfaces. IEEE Trans Image Process. 2009 Jun; 18(6):1358-65. View in: PubMed

Chou YY, Leporé N, Avedissian C, Madsen SK, Parikshak N, Hua X, Shaw LM, Trojanowski JQ, Weiner MW, Toga AW, Thompson PM. Mapping correlations between ventricular expansion and CSF amyloid and tau biomarkers in 240 subjects with Alzheimer's disease, mild cognitive impairment and elderly controls. Neuroimage. 2009 Jun; 46(2):394-410. View in: PubMed

Thompson PM, Bartzokis G, Hayashi KM, Klunder AD, Lu PH, Edwards N, Hong MS, Yu M, Geaga JA, Toga AW, Charles C, Perkins DO, McEvoy J, Hamer RM, Tohen M, Tollefson GD, Lieberman JA. Time-lapse mapping of cortical changes in schizophrenia with different treatments. Cereb Cortex. 2009 May; 19(5):1107-23. View in: PubMed

Shattuck DW, Joshi AA, Pantazis D, Kan E, Dutton RA, Sowell ER, Thompson PM, Toga AW, Leahy RM. Semi-automated method for delineation of landmarks on models of the cerebral cortex. J Neurosci Methods. 2009 Apr 15; 178(2):385-92. View in: PubMed

Leow AD, Yanovsky I, Parikshak N, Hua X, Lee S, Toga AW, Jack CR, Bernstein MA, Britson PJ, Gunter JL, Ward CP, Borowski B, Shaw LM, Trojanowski JQ, Fleisher AS, Harvey D, Kornak J, Schuff N, Alexander GE, Weiner MW, Thompson PM. Alzheimer's disease neuroimaging initiative: a one-year follow up study using tensor-based morphometry correlating degenerative rates, biomarkers and cognition. Neuroimage. 2009 Apr 15; 45(3):645-55. View in: PubMed

Morra JH, Tu Z, Apostolova LG, Green AE, Avedissian C, Madsen SK, Parikshak N, Toga AW, Jack CR, Schuff N, Weiner MW, Thompson PM. Automated mapping of hippocampal atrophy in 1-year repeat MRI data from 490 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls. Neuroimage. 2009 Mar; 45(1 Suppl):S3-15. View in: PubMed

Shi Y, Tu Z, Reiss AL, Dutton RA, Lee AD, Galaburda AM, Dinov I, Thompson PM, Toga AW. Joint sulcal detection on cortical surfaces with graphical models and boosted priors. IEEE Trans Med Imaging. 2009 Mar; 28(3):361-73. View in: PubMed

Thompson PM, Miller MI, Poldrack RA, Nichols TE, Taylor JE, Worsley KJ, Ratnanather JT. Special issue on mathematics in brain imaging. Neuroimage. 2009 Mar; 45(1 Suppl):S1-2. View in: PubMed

Sun D, Phillips L, Velakoulis D, Yung A, McGorry PD, Wood SJ, van Erp TG, Thompson PM, Toga AW, Cannon TD, Pantelis C. Progressive brain structural changes mapped as psychosis develops in 'at risk' individuals. Schizophr Res. 2009 Mar; 108(1-3):85-92. View in: PubMed

Chiang MC, Barysheva M, Shattuck DW, Lee AD, Madsen SK, Avedissian C, Klunder AD, Toga AW, McMahon KL, de Zubicaray GI, Wright MJ, Srivastava A, Balov N, Thompson PM. Genetics of brain fiber architecture and intellectual performance. J Neurosci. 2009 Feb 18; 29(7):2212-24. View in: PubMed

Chou YY, Leporé N, Chiang MC, Avedissian C, Barysheva M, McMahon KL, de Zubicaray GI, Meredith M, Wright MJ, Toga AW, Thompson PM. Mapping genetic influences on ventricular structure in twins. Neuroimage. 2009 Feb 15; 44(4):1312-23. View in: PubMed

Wang Y, Chan TF, Toga AW, Thompson PM. Multivariate tensor-based brain anatomical surface morphometry via holomorphic one-forms. Med Image Comput Comput Assist Interv. 2009; 12(Pt 1):337-44. View in: PubMed

Hua X, Leow AD, Levitt JG, Caplan R, Thompson PM, Toga AW. Detecting brain growth patterns in normal children using tensor-based morphometry. Hum Brain Mapp. 2009 Jan; 30(1):209-19. View in: PubMed

Shi Y, Morra JH, Thompson PM, Toga AW. Inverse-consistent surface mapping with Laplace-Beltrami eigen-features. Inf Process Med Imaging. 2009; 21:467-78. View in: PubMed

Kim Y, Thompson PM, Toga AW, Vese L, Zhan L. HARDI denoising: variational regularization of the spherical apparent diffusion coefficient sADC. Inf Process Med Imaging. 2009; 21:515-27. View in: PubMed

Luders E, Narr KL, Hamilton LS, Phillips OR, Thompson PM, Valle JS, Del'Homme M, Strickland T, McCracken JT, Toga AW, Levitt JG. Decreased callosal thickness in attention-deficit/hyperactivity disorder. Biol Psychiatry. 2009 Jan 1; 65(1):84-8. View in: PubMed

Bearden CE, van Erp TG, Dutton RA, Lee AD, Simon TJ, Cannon TD, Emanuel BS, McDonald-McGinn D, Zackai EH, Thompson PM. Alterations in midline cortical thickness and gyrification patterns mapped in children with 22q11. 2 deletions. Cereb Cortex. 2009 Jan; 19(1):115-26. View in: PubMed

Bearden CE, Thompson PM, Avedissian C, Klunder AD, Nicoletti M, Dierschke N, Brambilla P, Soares JC. Altered hippocampal morphology in unmedicated patients with major depressive illness. ASN Neuro. 2009; 1(4). View in: PubMed

Macey PM, Richard CA, Kumar R, Woo MA, Ogren JA, Avedissian C, Thompson PM, Harper RM. Hippocampal volume reduction in congenital central hypoventilation syndrome. PLoS One. 2009; 4(7):e6436. View in: PubMed

Butters MA, Aizenstein HJ, Hayashi KM, Meltzer CC, Seaman J, Reynolds CF, Toga AW, Thompson PM, Becker JT. Three-dimensional surface mapping of the caudate nucleus in late-life depression. Am J Geriatr Psychiatry. 2009 Jan; 17(1):4-12. View in: PubMed

Small GW, Siddarth P, Burggren AC, Kepe V, Ercoli LM, Miller KJ, Lavretsky H, Thompson PM, Cole GM, Huang SC, Phelps ME, Bookheimer SY, Barrio JR. Influence of cognitive status, age, and APOE-4 genetic risk on brain FDDNP positron-emission tomography imaging in persons without dementia. Arch Gen Psychiatry. 2009 Jan; 66(1):81-7. View in: PubMed

Chiang MC, Avedissian C, Barysheva M, Toga AW, McMahon KL, de Zubicaray GI, Wright MJ, Thompson PM. Extending genetic linkage analysis to diffusion tensor images to map single gene effects on brain fiber architecture. Med Image Comput Comput Assist Interv. 2009; 12(Pt 2):506-13. View in: PubMed

Jahanshad N, Lee AD, Leporé N, Chou YY, Brun CC, Barysheva M, Toga AW, McMahon KL, de Zubicaray GI, Wright MJ, Thompson PM. Genetics of anisotropy asymmetry: registration and sample size effects. Med Image Comput Comput Assist Interv. 2009; 12(Pt 2):498-505. View in: PubMed

Morra JH, Tu Z, Toga AW, Thompson PM. Lossless online ensemble learning (LOEL) and its application to subcortical segmentation. Med Image Comput Comput Assist Interv. 2009; 12(Pt 2):432-40. View in: PubMed

Wang Y, Dai W, Gu X, Chan TF, Yau ST, Toga AW, Thompson PM. Teichmöller shape space theory and its application to brain morphometry. Med Image Comput Comput Assist Interv. 2009; 12(Pt 2):133-40. View in: PubMed

Lee AD, Leporé N, Brun C, Chou YY, Barysheva M, Chiang MC, Madsen SK, de Zubicaray GI, McMahon KL, Wright MJ, Toga AW, Thompson PM. Tensor-based analysis of genetic influences on brain integrity using DTI in 100 twins. Med Image Comput Comput Assist Interv. 2009; 12(Pt 1):967-74. View in: PubMed

Goh A, Lenglet C, Thompson PM, Vidal R. Estimating orientation distribution functions with probability density constraints and spatial regularity. Med Image Comput Comput Assist Interv. 2009; 12(Pt 1):877-85. View in: PubMed

Zhan L, Leow AD, Zhu S, Baryshev M, Toga AW, McMahon KL, de Zubicaray GI, Wright MJ, Thompson PM. A novel measure of fractional anisotropy based on the tensor distribution function. Med Image Comput Comput Assist Interv. 2009; 12(Pt 1):845-52. View in: PubMed

Minnerop M, Luders E, Specht K, Ruhlmann J, Schneider-Gold C, Schröder R, Thompson PM, Toga AW, Klockgether T, Kornblum C. Grey and white matter loss along cerebral midline structures in myotonic dystrophy type 2. J Neurol. 2008 Dec; 255(12):1904-9. View in: PubMed

Frisoni GB, Ganzola R, Canu E, Rüb U, Pizzini FB, Alessandrini F, Zoccatelli G, Beltramello A, Caltagirone C, Thompson PM. Mapping local hippocampal changes in Alzheimer's disease and normal ageing with MRI at 3 Tesla. Brain. 2008 Dec; 131(Pt 12):3266-76. View in: PubMed

Klunder AD, Chiang MC, Dutton RA, Lee SE, Toga AW, Lopez OL, Aizenstein HJ, Becker JT, Thompson PM. Mapping cerebellar degeneration in HIV/AIDS. Neuroreport. 2008 Nov 19; 19(17):1655-9. View in: PubMed

Harris P, Alcantara DA, Amenta N, Lopez OL, Eiríksdóttir G, Sigurdsson S, Gudnason V, Madsen S, Thompson PM, Launer LJ, Carmichael OT. Localized measures of callosal atrophy are associated with late-life hypertension: AGES-Reykjavik Study. Neuroimage. 2008 Nov 15; 43(3):489-96. View in: PubMed

Hua X, Leow AD, Parikshak N, Lee S, Chiang MC, Toga AW, Jack CR, Weiner MW, Thompson PM. Tensor-based morphometry as a neuroimaging biomarker for Alzheimer's disease: an MRI study of 676 AD, MCI, and normal subjects. Neuroimage. 2008 Nov 15; 43(3):458-69. View in: PubMed

Morra JH, Tu Z, Apostolova LG, Green AE, Avedissian C, Madsen SK, Parikshak N, Hua X, Toga AW, Jack CR, Weiner MW, Thompson PM. Validation of a fully automated 3D hippocampal segmentation method using subjects with Alzheimer's disease mild cognitive impairment, and elderly controls. Neuroimage. 2008 Oct 15; 43(1):59-68. View in: PubMed

Gogtay N, Lu A, Leow AD, Klunder AD, Lee AD, Chavez A, Greenstein D, Giedd JN, Toga AW, Rapoport JL, Thompson PM. Three-dimensional brain growth abnormalities in childhood-onset schizophrenia visualized by using tensor-based morphometry. Proc Natl Acad Sci U S A. 2008 Oct 14; 105(41):15979-84. View in: PubMed

Narayan VM, Narr KL, Phillips OR, Thompson PM, Toga AW, Szeszko PR. Greater regional cortical gray matter thickness in obsessive-compulsive disorder. Neuroreport. 2008 Oct 8; 19(15):1551-5. View in: PubMed

Blokland GA, McMahon KL, Hoffman J, Zhu G, Meredith M, Martin NG, Thompson PM, de Zubicaray GI, Wright MJ. Quantifying the heritability of task-related brain activation and performance during the N-back working memory task: a twin fMRI study. Biol Psychol. 2008 Sep; 79(1):70-9. View in: PubMed

Bearden CE, Glahn DC, Lee AD, Chiang MC, van Erp TG, Cannon TD, Reiss AL, Toga AW, Thompson PM. Neural phenotypes of common and rare genetic variants. Biol Psychol. 2008 Sep; 79(1):43-57. View in: PubMed

Tiihonen J, Rossi R, Laakso MP, Hodgins S, Testa C, Perez J, Repo-Tiihonen E, Vaurio O, Soininen H, Aronen HJ, Könönen M, Thompson PM, Frisoni GB. Brain anatomy of persistent violent offenders: more rather than less. Psychiatry Res. 2008 Aug 30; 163(3):201-12. View in: PubMed

Vidal CN, Nicolson R, Boire JY, Barra V, DeVito TJ, Hayashi KM, Geaga JA, Drost DJ, Williamson PC, Rajakumar N, Toga AW, Thompson PM. Three-dimensional mapping of the lateral ventricles in autism. Psychiatry Res. 2008 Jul 15; 163(2):106-15. View in: PubMed

Ballmaier M, Kumar A, Elderkin-Thompson V, Narr KL, Luders E, Thompson PM, Hojatkashani C, Pham D, Heinz A, Toga AW. Mapping callosal morphology in early- and late-onset elderly depression: an index of distinct changes in cortical connectivity. Neuropsychopharmacology. 2008 Jun; 33(7):1528-36. View in: PubMed

Sowell ER, Kan E, Yoshii J, Thompson PM, Bansal R, Xu D, Toga AW, Peterson BS. Thinning of sensorimotor cortices in children with Tourette syndrome. Nat Neurosci. 2008 Jun; 11(6):637-9. View in: PubMed

Hua X, Leow AD, Lee S, Klunder AD, Toga AW, Lepore N, Chou YY, Brun C, Chiang MC, Barysheva M, Jack CR, Bernstein MA, Britson PJ, Ward CP, Whitwell JL, Borowski B, Fleisher AS, Fox NC, Boyes RG, Barnes J, Harvey D, Kornak J, Schuff N, Boreta L, Alexander GE, Weiner MW, Thompson PM. 3D characterization of brain atrophy in Alzheimer's disease and mild cognitive impairment using tensor-based morphometry. Neuroimage. 2008 May 15; 41(1):19-34. View in: PubMed

Bearden CE, Soares JC, Klunder AD, Nicoletti M, Dierschke N, Hayashi KM, Narr KL, Brambilla P, Sassi RB, Axelson D, Ryan N, Birmaher B, Thompson PM. Three-dimensional mapping of hippocampal anatomy in adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry. 2008 May; 47(5):515-25. View in: PubMed

Bearden CE, Thompson PM, Dutton RA, Frey BN, Peluso MA, Nicoletti M, Dierschke N, Hayashi KM, Klunder AD, Glahn DC, Brambilla P, Sassi RB, Mallinger AG, Soares JC. Three-dimensional mapping of hippocampal anatomy in unmedicated and lithium-treated patients with bipolar disorder. Neuropsychopharmacology. 2008 May; 33(6):1229-38. View in: PubMed

Xu Y, Valentino DJ, Scher AI, Dinov I, White LR, Thompson PM, Launer LJ, Toga AW. Age effects on hippocampal structural changes in old men: the HAAS. Neuroimage. 2008 Apr 15; 40(3):1003-15. View in: PubMed

Chou YY, Leporé N, de Zubicaray GI, Carmichael OT, Becker JT, Toga AW, Thompson PM. Automated ventricular mapping with multi-atlas fluid image alignment reveals genetic effects in Alzheimer's disease. Neuroimage. 2008 Apr 1; 40(2):615-30. View in: PubMed

Boyes RG, Gunter JL, Frost C, Janke AL, Yeatman T, Hill DL, Bernstein MA, Thompson PM, Weiner MW, Schuff N, Alexander GE, Killiany RJ, DeCarli C, Jack CR, Fox NC. Intensity non-uniformity correction using N3 on 3-T scanners with multichannel phased array coils. Neuroimage. 2008 Feb 15; 39(4):1752-62. View in: PubMed

Small GW, Bookheimer SY, Thompson PM, Cole GM, Huang SC, Kepe V, Barrio JR. Current and future uses of neuroimaging for cognitively impaired patients. Lancet Neurol. 2008 Feb; 7(2):161-72. View in: PubMed

Ballmaier M, Narr KL, Toga AW, Elderkin-Thompson V, Thompson PM, Hamilton L, Haroon E, Pham D, Heinz A, Kumar A. Hippocampal morphology and distinguishing late-onset from early-onset elderly depression. Am J Psychiatry. 2008 Feb; 165(2):229-37. View in: PubMed

Foland LC, Altshuler LL, Sugar CA, Lee AD, Leow AD, Townsend J, Narr KL, Asuncion DM, Toga AW, Thompson PM. Increased volume of the amygdala and hippocampus in bipolar patients treated with lithium. Neuroreport. 2008 Jan 22; 19(2):221-4. View in: PubMed

Foland LC, Altshuler LL, Bookheimer SY, Eisenberger N, Townsend J, Thompson PM. Evidence for deficient modulation of amygdala response by prefrontal cortex in bipolar mania. Psychiatry Res. 2008 Jan 15; 162(1):27-37. View in: PubMed

Kochunov P, Thompson PM, Coyle TR, Lancaster JL, Kochunov V, Royall D, Mangin JF, Rivière D, Fox PT. Relationship among neuroimaging indices of cerebral health during normal aging. Hum Brain Mapp. 2008 Jan; 29(1):36-45. View in: PubMed

Chiang MC, Barysheva M, Lee AD, Madsen S, Klunder AD, Toga AW, Mcmahon KL, de Zubicaray GI, Meredith M, Wright MJ, Srivastava A, Balov N, Thompson PM. Brain fiber architecture, genetics, and intelligence: a high angular resolution diffusion imaging (HARDI) study. Med Image Comput Comput Assist Interv. 2008; 11(Pt 1):1060-7. View in: PubMed

Apostolova LG, Lu P, Rogers S, Dutton RA, Hayashi KM, Toga AW, Cummings JL, Thompson PM. 3D mapping of language networks in clinical and pre-clinical Alzheimer's disease. Brain Lang. 2008 Jan; 104(1):33-41. View in: PubMed

Shattuck DW, Chiang MC, Barysheva M, McMahon KL, de Zubicaray GI, Meredith M, Wright MJ, Toga AW, Thompson PM. Visualization tools for high angular resolution diffusion imaging. Med Image Comput Comput Assist Interv. 2008; 11(Pt 2):298-305. View in: PubMed

Wang Y, Gu X, Chan TF, Thompson PM, Yau ST. Conformal slit mapping and its applications to brain surface parameterization. Med Image Comput Comput Assist Interv. 2008; 11(Pt 1):585-93. View in: PubMed

Gothelf D, Furfaro JA, Hoeft F, Eckert MA, Hall SS, O'Hara R, Erba HW, Ringel J, Hayashi KM, Patnaik S, Golianu B, Kraemer HC, Thompson PM, Piven J, Reiss AL. Neuroanatomy of fragile X syndrome is associated with aberrant behavior and the fragile X mental retardation protein (FMRP). Ann Neurol. 2008 Jan; 63(1):40-51. View in: PubMed

Apostolova LG, Thompson PM. Mapping progressive brain structural changes in early Alzheimer's disease and mild cognitive impairment. Neuropsychologia. 2008; 46(6):1597-612. View in: PubMed

Sowell ER, Mattson SN, Kan E, Thompson PM, Riley EP, Toga AW. Abnormal cortical thickness and brain-behavior correlation patterns in individuals with heavy prenatal alcohol exposure. Cereb Cortex. 2008 Jan; 18(1):136-44. View in: PubMed

Morra JH, Tu Z, Apostolova LG, Green AE, Toga AW, Thompson PM. Automatic subcortical segmentation using a contextual model. Med Image Comput Comput Assist Interv. 2008; 11(Pt 1):194-201. View in: PubMed

Brun C, Leporé N, Pennec X, Chou YY, Lee AD, Barysheva M, de Zubicaray G, Meredith M, McMahon K, Wright MJ, Toga AW, Thompson PM. A tensor-based morphometry study of genetic influences on brain structure using a new fluid registration method. Med Image Comput Comput Assist Interv. 2008; 11(Pt 2):914-21. View in: PubMed

Liu X, Mio W, Shi Y, Dinov I, Liu X, Leporé N, Leporé F, Fortin M, Voss P, Lassonde M, Thompson PM. Models of normal variation and local contrasts in hippocampal anatomy. Med Image Comput Comput Assist Interv. 2008; 11(Pt 2):407-15. View in: PubMed

Weber B, Luders E, Faber J, Richter S, Quesada CM, Urbach H, Thompson PM, Toga AW, Elger CE, Helmstaedter C. Distinct regional atrophy in the corpus callosum of patients with temporal lobe epilepsy. Brain. 2007 Dec; 130(Pt 12):3149-54. View in: PubMed

Joshi AA, Shattuck DW, Thompson PM, Leahy RM. Surface-constrained volumetric brain registration using harmonic mappings. IEEE Trans Med Imaging. 2007 Dec; 26(12):1657-69. View in: PubMed

Rüsch N, Luders E, Lieb K, Zahn R, Ebert D, Thompson PM, Toga AW, van Elst LT. Corpus callosum abnormalities in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder. J Psychiatry Neurosci. 2007 Nov; 32(6):417-22. View in: PubMed

Apostolova LG, Steiner CA, Akopyan GG, Dutton RA, Hayashi KM, Toga AW, Cummings JL, Thompson PM. Three-dimensional gray matter atrophy mapping in mild cognitive impairment and mild Alzheimer disease. Arch Neurol. 2007 Oct; 64(10):1489-95. View in: PubMed

Luders E, Narr KL, Bilder RM, Thompson PM, Szeszko PR, Hamilton L, Toga AW. Positive correlations between corpus callosum thickness and intelligence. Neuroimage. 2007 Oct 1; 37(4):1457-64. View in: PubMed

Toga AW, Thompson PM. What is where and why it is important. Neuroimage. 2007 Oct 1; 37(4):1045-9; discussion 1066-8. View in: PubMed

Hamilton LS, Narr KL, Luders E, Szeszko PR, Thompson PM, Bilder RM, Toga AW. Asymmetries of cortical thickness: effects of handedness, sex, and schizophrenia. Neuroreport. 2007 Sep 17; 18(14):1427-31. View in: PubMed

Shi Y, Thompson PM, de Zubicaray GI, Rose SE, Tu Z, Dinov I, Toga AW. Direct mapping of hippocampal surfaces with intrinsic shape context. Neuroimage. 2007 Sep 1; 37(3):792-807. View in: PubMed

Narr KL, Woods RP, Thompson PM, Szeszko P, Robinson D, Dimtcheva T, Gurbani M, Toga AW, Bilder RM. Relationships between IQ and regional cortical gray matter thickness in healthy adults. Cereb Cortex. 2007 Sep; 17(9):2163-71. View in: PubMed

Lin JJ, Salamon N, Lee AD, Dutton RA, Geaga JA, Hayashi KM, Luders E, Toga AW, Engel J, Thompson PM. Reduced neocortical thickness and complexity mapped in mesial temporal lobe epilepsy with hippocampal sclerosis. Cereb Cortex. 2007 Sep; 17(9):2007-18. View in: PubMed

Narayan VM, Narr KL, Kumari V, Woods RP, Thompson PM, Toga AW, Sharma T. Regional cortical thinning in subjects with violent antisocial personality disorder or schizophrenia. Am J Psychiatry. 2007 Sep; 164(9):1418-27. View in: PubMed

Gogtay N, Ordonez A, Herman DH, Hayashi KM, Greenstein D, Vaituzis C, Lenane M, Clasen L, Sharp W, Giedd JN, Jung D, Nugent TF, Toga AW, Leibenluft E, Thompson PM, Rapoport JL. Dynamic mapping of cortical development before and after the onset of pediatric bipolar illness. J Child Psychol Psychiatry. 2007 Sep; 48(9):852-62. View in: PubMed

Bearden CE, van Erp TG, Dutton RA, Tran H, Zimmermann L, Sun D, Geaga JA, Simon TJ, Glahn DC, Cannon TD, Emanuel BS, Toga AW, Thompson PM. Mapping cortical thickness in children with 22q11. 2 deletions. Cereb Cortex. 2007 Aug; 17(8):1889-98. View in: PubMed

Chiang MC, Reiss AL, Lee AD, Bellugi U, Galaburda AM, Korenberg JR, Mills DL, Toga AW, Thompson PM. 3D pattern of brain abnormalities in Williams syndrome visualized using tensor-based morphometry. Neuroimage. 2007 Jul 15; 36(4):1096-109. View in: PubMed

Lenroot RK, Gogtay N, Greenstein DK, Wells EM, Wallace GL, Clasen LS, Blumenthal JD, Lerch J, Zijdenbos AP, Evans AC, Thompson PM, Giedd JN. Sexual dimorphism of brain developmental trajectories during childhood and adolescence. Neuroimage. 2007 Jul 15; 36(4):1065-73. View in: PubMed

Bearden CE, Thompson PM, Dalwani M, Hayashi KM, Lee AD, Nicoletti M, Trakhtenbroit M, Glahn DC, Brambilla P, Sassi RB, Mallinger AG, Frank E, Kupfer DJ, Soares JC. Greater cortical gray matter density in lithium-treated patients with bipolar disorder. Biol Psychiatry. 2007 Jul 1; 62(1):7-16. View in: PubMed

Sowell ER, Peterson BS, Kan E, Woods RP, Yoshii J, Bansal R, Xu D, Zhu H, Thompson PM, Toga AW. Sex differences in cortical thickness mapped in 176 healthy individuals between 7 and 87 years of age. Cereb Cortex. 2007 Jul; 17(7):1550-60. View in: PubMed

Apostolova LG, Thompson PM. Brain mapping as a tool to study neurodegeneration. Neurotherapeutics. 2007 Jul; 4(3):387-400. View in: PubMed

Shi Y, Thompson PM, Dinov I, Osher S, Toga AW. Direct cortical mapping via solving partial differential equations on implicit surfaces. Med Image Anal. 2007 Jun; 11(3):207-23. View in: PubMed

Glahn DC, Paus T, Thompson PM. Imaging genomics: mapping the influence of genetics on brain structure and function. Hum Brain Mapp. 2007 Jun; 28(6):461-3. View in: PubMed

Glahn DC, Thompson PM, Blangero J. Neuroimaging endophenotypes: strategies for finding genes influencing brain structure and function. Hum Brain Mapp. 2007 Jun; 28(6):488-501. View in: PubMed

Wang Y, Lui LM, Gu X, Hayashi KM, Chan TF, Toga AW, Thompson PM, Yau ST. Brain surface conformal parameterization using Riemann surface structure. IEEE Trans Med Imaging. 2007 Jun; 26(6):853-65. View in: PubMed

Leow AD, Yanovsky I, Chiang MC, Lee AD, Klunder AD, Lu A, Becker JT, Davis SW, Toga AW, Thompson PM. Statistical properties of Jacobian maps and the realization of unbiased large-deformation nonlinear image registration. IEEE Trans Med Imaging. 2007 Jun; 26(6):822-32. View in: PubMed

Bearden CE, van Erp TG, Thompson PM, Toga AW, Cannon TD. Cortical mapping of genotype-phenotype relationships in schizophrenia. Hum Brain Mapp. 2007 Jun; 28(6):519-32. View in: PubMed

Tu Z, Zheng S, Yuille AL, Reiss AL, Dutton RA, Lee AD, Galaburda AM, Dinov I, Thompson PM, Toga AW. Automated extraction of the cortical sulci based on a supervised learning approach. IEEE Trans Med Imaging. 2007 Apr; 26(4):541-52. View in: PubMed

Frisoni GB, Pievani M, Testa C, Sabattoli F, Bresciani L, Bonetti M, Beltramello A, Hayashi KM, Toga AW, Thompson PM. The topography of grey matter involvement in early and late onset Alzheimer's disease. Brain. 2007 Mar; 130(Pt 3):720-30. View in: PubMed

Carmichael OT, Kuller LH, Lopez OL, Thompson PM, Dutton RA, Lu A, Lee SE, Lee JY, Aizenstein HJ, Meltzer CC, Liu Y, Toga AW, Becker JT. Ventricular volume and dementia progression in the Cardiovascular Health Study. Neurobiol Aging. 2007 Mar; 28(3):389-97. View in: PubMed

Luders E, Di Paola M, Tomaiuolo F, Thompson PM, Toga AW, Vicari S, Petrides M, Caltagirone C. Callosal morphology in Williams syndrome: a new evaluation of shape and thickness. Neuroreport. 2007 Feb 12; 18(3):203-7. View in: PubMed

Lee AD, Leow AD, Lu A, Reiss AL, Hall S, Chiang MC, Toga AW, Thompson PM. 3D pattern of brain abnormalities in Fragile X syndrome visualized using tensor-based morphometry. Neuroimage. 2007 Feb 1; 34(3):924-38. View in: PubMed

Narr KL, Bilder RM, Luders E, Thompson PM, Woods RP, Robinson D, Szeszko PR, Dimtcheva T, Gurbani M, Toga AW. Asymmetries of cortical shape: Effects of handedness, sex and schizophrenia. Neuroimage. 2007 Feb 1; 34(3):939-48. View in: PubMed

Nugent TF, Herman DH, Ordonez A, Greenstein D, Hayashi KM, Lenane M, Clasen L, Jung D, Toga AW, Giedd JN, Rapoport JL, Thompson PM, Gogtay N. Dynamic mapping of hippocampal development in childhood onset schizophrenia. Schizophr Res. 2007 Feb; 90(1-3):62-70. View in: PubMed

Thompson PM, Hayashi KM, Dutton RA, Chiang MC, Leow AD, Sowell ER, De Zubicaray G, Becker JT, Lopez OL, Aizenstein HJ, Toga AW. Tracking Alzheimer's disease. Ann N Y Acad Sci. 2007 Feb; 1097:183-214. View in: PubMed

Fillard P, Arsigny V, Pennec X, Hayashi KM, Thompson PM, Ayache N. Measuring brain variability by extrapolating sparse tensor fields measured on sulcal lines. Neuroimage. 2007 Jan 15; 34(2):639-50. View in: PubMed

Chiang MC, Dutton RA, Hayashi KM, Lopez OL, Aizenstein HJ, Toga AW, Becker JT, Thompson PM. 3D pattern of brain atrophy in HIV/AIDS visualized using tensor-based morphometry. Neuroimage. 2007 Jan 1; 34(1):44-60. View in: PubMed

Chiang MC, Klunder AD, McMahon K, de Zubicaray GI, Wright MJ, Toga AW, Thompson PM. Information-theoretic analysis of brain white matter fiber orientation distribution functions. Inf Process Med Imaging. 2007; 20:172-82. View in: PubMed

Carmichael OT, Kuller LH, Lopez OL, Thompson PM, Dutton RA, Lu A, Lee SE, Lee JY, Aizenstein HJ, Meltzer CC, Liu Y, Toga AW, Becker JT. Cerebral ventricular changes associated with transitions between normal cognitive function, mild cognitive impairment, and dementia. Alzheimer Dis Assoc Disord. 2007 Jan-Mar; 21(1):14-24. View in: PubMed

Apostolova LG, Akopyan GG, Partiali N, Steiner CA, Dutton RA, Hayashi KM, Dinov ID, Toga AW, Cummings JL, Thompson PM. Structural correlates of apathy in Alzheimer's disease. Dement Geriatr Cogn Disord. 2007; 24(2):91-7. View in: PubMed

Leporé N, Brun C, Pennec X, Chou YY, Lopez OL, Aizenstein HJ, Becker JT, Toga AW, Thompson PM. Mean template for tensor-based morphometry using deformation tensors. Med Image Comput Comput Assist Interv. 2007; 10(Pt 2):826-33. View in: PubMed

Shi Y, Tu Z, Reiss AL, Dutton RA, Lee AD, Galaburda AM, Dinov I, Thompson PM, Toga AW. Joint sulci detection using graphical models and boosted priors. Inf Process Med Imaging. 2007; 20:98-109. View in: PubMed

Small GW, Kepe V, Ercoli LM, Siddarth P, Bookheimer SY, Miller KJ, Lavretsky H, Burggren AC, Cole GM, Vinters HV, Thompson PM, Huang SC, Satyamurthy N, Phelps ME, Barrio JR. PET of brain amyloid and tau in mild cognitive impairment. N Engl J Med. 2006 Dec 21; 355(25):2652-63. View in: PubMed

Toga AW, Thompson PM, Mori S, Amunts K, Zilles K. Towards multimodal atlases of the human brain. Nat Rev Neurosci. 2006 Dec; 7(12):952-66. View in: PubMed

Nicolson R, DeVito TJ, Vidal CN, Sui Y, Hayashi KM, Drost DJ, Williamson PC, Rajakumar N, Toga AW, Thompson PM. Detection and mapping of hippocampal abnormalities in autism. Psychiatry Res. 2006 Nov 22; 148(1):11-21. View in: PubMed

Apostolova LG, Dinov ID, Dutton RA, Hayashi KM, Toga AW, Cummings JL, Thompson PM. 3D comparison of hippocampal atrophy in amnestic mild cognitive impairment and Alzheimer's disease. Brain. 2006 Nov; 129(Pt 11):2867-73. View in: PubMed

Gaser C, Luders E, Thompson PM, Lee AD, Dutton RA, Geaga JA, Hayashi KM, Bellugi U, Galaburda AM, Korenberg JR, Mills DL, Toga AW, Reiss AL. Increased local gyrification mapped in Williams syndrome. Neuroimage. 2006 Oct 15; 33(1):46-54. View in: PubMed

Apostolova LG, Lu PH, Rogers S, Dutton RA, Hayashi KM, Toga AW, Cummings JL, Thompson PM. 3D mapping of mini-mental state examination performance in clinical and preclinical Alzheimer disease. Alzheimer Dis Assoc Disord. 2006 Oct-Dec; 20(4):224-31. View in: PubMed

Vidal CN, Nicolson R, DeVito TJ, Hayashi KM, Geaga JA, Drost DJ, Williamson PC, Rajakumar N, Sui Y, Dutton RA, Toga AW, Thompson PM. Mapping corpus callosum deficits in autism: an index of aberrant cortical connectivity. Biol Psychiatry. 2006 Aug 1; 60(3):218-25. View in: PubMed

Luders E, Narr KL, Zaidel E, Thompson PM, Toga AW. Gender effects on callosal thickness in scaled and unscaled space. Neuroreport. 2006 Jul 31; 17(11):1103-6. View in: PubMed

Leow AD, Klunder AD, Jack CR, Toga AW, Dale AM, Bernstein MA, Britson PJ, Gunter JL, Ward CP, Whitwell JL, Borowski BJ, Fleisher AS, Fox NC, Harvey D, Kornak J, Schuff N, Studholme C, Alexander GE, Weiner MW, Thompson PM. Longitudinal stability of MRI for mapping brain change using tensor-based morphometry. Neuroimage. 2006 Jun; 31(2):627-40. View in: PubMed

Xu M, Thompson PM, Toga AW. Adaptive reproducing kernel particle method for extraction of the cortical surface. IEEE Trans Med Imaging. 2006 Jun; 25(6):755-67. View in: PubMed

Pitiot A, Bardinet E, Thompson PM, Malandain G. Piecewise affine registration of biological images for volume reconstruction. Med Image Anal. 2006 Jun; 10(3):465-83. View in: PubMed

Thompson PM, Dutton RA, Hayashi KM, Lu A, Lee SE, Lee JY, Lopez OL, Aizenstein HJ, Toga AW, Becker JT. 3D mapping of ventricular and corpus callosum abnormalities in HIV/AIDS. Neuroimage. 2006 May 15; 31(1):12-23. View in: PubMed

Apostolova LG, Dutton RA, Dinov ID, Hayashi KM, Toga AW, Cummings JL, Thompson PM. Conversion of mild cognitive impairment to Alzheimer disease predicted by hippocampal atrophy maps. Arch Neurol. 2006 May; 63(5):693-9. View in: PubMed

Toga AW, Thompson PM, Sowell ER. Mapping brain maturation. Trends Neurosci. 2006 Mar; 29(3):148-59. View in: PubMed

Hendry J, DeVito T, Gelman N, Densmore M, Rajakumar N, Pavlosky W, Williamson PC, Thompson PM, Drost DJ, Nicolson R. White matter abnormalities in autism detected through transverse relaxation time imaging. Neuroimage. 2006 Feb 15; 29(4):1049-57. View in: PubMed

Narr KL, Bilder RM, Woods RP, Thompson PM, Szeszko P, Robinson D, Ballmaier M, Messenger B, Wang Y, Toga AW. Regional specificity of cerebrospinal fluid abnormalities in first episode schizophrenia. Psychiatry Res. 2006 Jan 30; 146(1):21-33. View in: PubMed

Cannon TD, Thompson PM, van Erp TG, Huttunen M, Lonnqvist J, Kaprio J, Toga AW. Mapping heritability and molecular genetic associations with cortical features using probabilistic brain atlases: methods and applications to schizophrenia. Neuroinformatics. 2006; 4(1):5-19. View in: PubMed

Lepore N, Brun CA, Chiang MC, Chou YY, Dutton RA, Hayashi KM, Lopez OL, Aizenstein HJ, Toga AW, Becker JT, Thompson PM. Multivariate statistics of the Jacobian matrices in tensor based morphometry and their application to HIV/AIDS. Med Image Comput Comput Assist Interv. 2006; 9(Pt 1):191-8. View in: PubMed

Lui LM, Wang Y, Chan TF, Thompson PM. A landmark-based brain conformal parametrization with automatic landmark tracking technique. Med Image Comput Comput Assist Interv. 2006; 9(Pt 2):308-15. View in: PubMed

Gogtay N, Nugent TF, Herman DH, Ordonez A, Greenstein D, Hayashi KM, Clasen L, Toga AW, Giedd JN, Rapoport JL, Thompson PM. Dynamic mapping of normal human hippocampal development. Hippocampus. 2006; 16(8):664-72. View in: PubMed

Zheng S, Tu Z, Yuille AL, Reiss AL, Dutton RA, Lee AD, Galaburda AM, Thompson PM, Dinov I, Toga AW. A learning based algorithm for automatic extraction of the cortical sulci. Med Image Comput Comput Assist Interv. 2006; 9(Pt 1):695-703. View in: PubMed

Wang Y, Gu X, Chan TF, Thompson PM, Yau ST. Brain surface conformal parameterization with algebraic functions. Med Image Comput Comput Assist Interv. 2006; 9(Pt 2):946-54. View in: PubMed

Vidal CN, Rapoport JL, Hayashi KM, Geaga JA, Sui Y, McLemore LE, Alaghband Y, Giedd JN, Gochman P, Blumenthal J, Gogtay N, Nicolson R, Toga AW, Thompson PM. Dynamically spreading frontal and cingulate deficits mapped in adolescents with schizophrenia. Arch Gen Psychiatry. 2006 Jan; 63(1):25-34. View in: PubMed

Becker JT, Davis SW, Hayashi KM, Meltzer CC, Toga AW, Lopez OL, Thompson PM. Three-dimensional patterns of hippocampal atrophy in mild cognitive impairment. Arch Neurol. 2006 Jan; 63(1):97-101. View in: PubMed

London ED, Berman SM, Voytek B, Simon SL, Mandelkern MA, Monterosso J, Thompson PM, Brody AL, Geaga JA, Hong MS, Hayashi KM, Rawson RA, Ling W. Cerebral metabolic dysfunction and impaired vigilance in recently abstinent methamphetamine abusers. Biol Psychiatry. 2005 Nov 15; 58(10):770-8. View in: PubMed

Cannon TD, Hennah W, van Erp TG, Thompson PM, Lonnqvist J, Huttunen M, Gasperoni T, Tuulio-Henriksson A, Pirkola T, Toga AW, Kaprio J, Mazziotta J, Peltonen L. Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory. Arch Gen Psychiatry. 2005 Nov; 62(11):1205-13. View in: PubMed

Thompson PM, Dutton RA, Hayashi KM, Toga AW, Lopez OL, Aizenstein HJ, Becker JT. Thinning of the cerebral cortex visualized in HIV/AIDS reflects CD4+ T lymphocyte decline. Proc Natl Acad Sci U S A. 2005 Oct 25; 102(43):15647-52. View in: PubMed

Carmichael OT, Aizenstein HA, Davis SW, Becker JT, Thompson PM, Meltzer CC, Liu Y. Atlas-based hippocampus segmentation in Alzheimer's disease and mild cognitive impairment. Neuroimage. 2005 Oct 1; 27(4):979-90. View in: PubMed

O'Hare ED, Kan E, Yoshii J, Mattson SN, Riley EP, Thompson PM, Toga AW, Sowell ER. Mapping cerebellar vermal morphology and cognitive correlates in prenatal alcohol exposure. Neuroreport. 2005 Aug 22; 16(12):1285-90. View in: PubMed

Mega MS, Dinov ID, Mazziotta JC, Manese M, Thompson PM, Lindshield C, Moussai J, Tran N, Olsen K, Zoumalan CI, Woods RP, Toga AW. Automated brain tissue assessment in the elderly and demented population: construction and validation of a sub-volume probabilistic brain atlas. Neuroimage. 2005 Jul 15; 26(4):1009-18. View in: PubMed

Narr KL, Toga AW, Szeszko P, Thompson PM, Woods RP, Robinson D, Sevy S, Wang Y, Schrock K, Bilder RM. Cortical thinning in cingulate and occipital cortices in first episode schizophrenia. Biol Psychiatry. 2005 Jul 1; 58(1):32-40. View in: PubMed

Rasser PE, Johnston P, Lagopoulos J, Ward PB, Schall U, Thienel R, Bender S, Toga AW, Thompson PM. Functional MRI BOLD response to Tower of London performance of first-episode schizophrenia patients using cortical pattern matching. Neuroimage. 2005 Jul 1; 26(3):941-51. View in: PubMed

Narr KL, Bilder RM, Toga AW, Woods RP, Rex DE, Szeszko PR, Robinson D, Sevy S, Gunduz-Bruce H, Wang YP, DeLuca H, Thompson PM. Mapping cortical thickness and gray matter concentration in first episode schizophrenia. Cereb Cortex. 2005 Jun; 15(6):708-19. View in: PubMed

Thompson PM, Lee AD, Dutton RA, Geaga JA, Hayashi KM, Eckert MA, Bellugi U, Galaburda AM, Korenberg JR, Mills DL, Toga AW, Reiss AL. Abnormal cortical complexity and thickness profiles mapped in Williams syndrome. J Neurosci. 2005 Apr 20; 25(16):4146-58. View in: PubMed

Kochunov P, Lancaster J, Hardies J, Thompson PM, Woods RP, Cody JD, Hale DE, Laird A, Fox PT. Mapping structural differences of the corpus callosum in individuals with 18q deletions using targetless regional spatial normalization. Hum Brain Mapp. 2005 Apr; 24(4):325-31. View in: PubMed

Toga AW, Thompson PM. Brain atlases of normal and diseased populations. Int Rev Neurobiol. 2005; 66:1-54. View in: PubMed

Joshi AA, Shattuck DW, Thompson PM, Leahy RM. A framework for registration, statistical characterization and classification of cortically constrained functional imaging data. Inf Process Med Imaging. 2005; 19:186-96. View in: PubMed

Fillard P, Arsigny V, Pennec X, Thompson PM, Ayache N. Extrapolation of sparse tensor fields: application to the modeling of brain variability. Inf Process Med Imaging. 2005; 19:27-38. View in: PubMed

Wang Y, Chiang MC, Thompson PM. Automated surface matching using mutual information applied to Riemann surface structures. Med Image Comput Comput Assist Interv. 2005; 8(Pt 2):666-74. View in: PubMed

Wang Y, Lui LM, Chan TF, Thompson PM. Optimization of brain conformal mapping with landmarks. Med Image Comput Comput Assist Interv. 2005; 8(Pt 2):675-83. View in: PubMed

Thompson PM, Sowell ER, Gogtay N, Giedd JN, Vidal CN, Hayashi KM, Leow A, Nicolson R, Rapoport JL, Toga AW. Structural MRI and brain development. Int Rev Neurobiol. 2005; 67:285-323. View in: PubMed

Toga AW, Thompson PM. Genetics of brain structure and intelligence. Annu Rev Neurosci. 2005; 28:1-23. View in: PubMed

Wang Y, Gu X, Hayashi KM, Chan TF, Thompson PM, Yau ST. Brain surface parameterization using Riemann surface structure. Med Image Comput Comput Assist Interv. 2005; 8(Pt 2):657-65. View in: PubMed

Ballmaier M, Kumar A, Thompson PM, Narr KL, Lavretsky H, Estanol L, Deluca H, Toga AW. Localizing gray matter deficits in late-onset depression using computational cortical pattern matching methods. Am J Psychiatry. 2004 Nov; 161(11):2091-9. View in: PubMed

Sowell ER, Thompson PM, Leonard CM, Welcome SE, Kan E, Toga AW. Longitudinal mapping of cortical thickness and brain growth in normal children. J Neurosci. 2004 Sep 22; 24(38):8223-31. View in: PubMed

Ballmaier M, O'Brien JT, Burton EJ, Thompson PM, Rex DE, Narr KL, McKeith IG, DeLuca H, Toga AW. Comparing gray matter loss profiles between dementia with Lewy bodies and Alzheimer's disease using cortical pattern matching: diagnosis and gender effects. Neuroimage. 2004 Sep; 23(1):325-35. View in: PubMed

Gu X, Wang Y, Chan TF, Thompson PM, Yau ST. Genus zero surface conformal mapping and its application to brain surface mapping. IEEE Trans Med Imaging. 2004 Aug; 23(8):949-58. View in: PubMed

Luders E, Narr KL, Thompson PM, Rex DE, Jancke L, Steinmetz H, Toga AW. Gender differences in cortical complexity. Nat Neurosci. 2004 Aug; 7(8):799-800. View in: PubMed

Thompson PM, Hayashi KM, De Zubicaray GI, Janke AL, Rose SE, Semple J, Hong MS, Herman DH, Gravano D, Doddrell DM, Toga AW. Mapping hippocampal and ventricular change in Alzheimer disease. Neuroimage. 2004 Aug; 22(4):1754-66. View in: PubMed

Sowell ER, Thompson PM, Toga AW. Mapping changes in the human cortex throughout the span of life. Neuroscientist. 2004 Aug; 10(4):372-92. View in: PubMed

Thompson PM, Hayashi KM, Simon SL, Geaga JA, Hong MS, Sui Y, Lee JY, Toga AW, Ling W, London ED. Structural abnormalities in the brains of human subjects who use methamphetamine. J Neurosci. 2004 Jun 30; 24(26):6028-36. View in: PubMed

Blanton RE, Levitt JG, Peterson JR, Fadale D, Sporty ML, Lee M, To D, Mormino EC, Thompson PM, McCracken JT, Toga AW. Gender differences in the left inferior frontal gyrus in normal children. Neuroimage. 2004 Jun; 22(2):626-36. View in: PubMed

Gogtay N, Giedd JN, Lusk L, Hayashi KM, Greenstein D, Vaituzis AC, Nugent TF, Herman DH, Clasen LS, Toga AW, Rapoport JL, Thompson PM. Dynamic mapping of human cortical development during childhood through early adulthood. Proc Natl Acad Sci U S A. 2004 May 25; 101(21):8174-9. View in: PubMed

Narr KL, Bilder RM, Kim S, Thompson PM, Szeszko P, Robinson D, Luders E, Toga AW. Abnormal gyral complexity in first-episode schizophrenia. Biol Psychiatry. 2004 Apr 15; 55(8):859-67. View in: PubMed

Narr KL, Thompson PM, Szeszko P, Robinson D, Jang S, Woods RP, Kim S, Hayashi KM, Asunction D, Toga AW, Bilder RM. Regional specificity of hippocampal volume reductions in first-episode schizophrenia. Neuroimage. 2004 Apr; 21(4):1563-75. View in: PubMed

Ballmaier M, Sowell ER, Thompson PM, Kumar A, Narr KL, Lavretsky H, Welcome SE, DeLuca H, Toga AW. Mapping brain size and cortical gray matter changes in elderly depression. Biol Psychiatry. 2004 Feb 15; 55(4):382-9. View in: PubMed

Xu M, Thompson PM, Toga AW. An adaptive level set segmentation on a triangulated mesh. IEEE Trans Med Imaging. 2004 Feb; 23(2):191-201. View in: PubMed

Pitiot A, Delingette H, Thompson PM, Ayache N. Expert knowledge-guided segmentation system for brain MRI. Neuroimage. 2004; 23 Suppl 1:S85-96. View in: PubMed

Thompson PM, Hayashi KM, Sowell ER, Gogtay N, Giedd JN, Rapoport JL, de Zubicaray GI, Janke AL, Rose SE, Semple J, Doddrell DM, Wang Y, van Erp TG, Cannon TD, Toga AW. Mapping cortical change in Alzheimer's disease, brain development, and schizophrenia. Neuroimage. 2004; 23 Suppl 1:S2-18. View in: PubMed

Narr KL, Sharma T, Woods RP, Thompson PM, Sowell ER, Rex D, Kim S, Asuncion D, Jang S, Mazziotta J, Toga AW. Increases in regional subarachnoid CSF without apparent cortical gray matter deficits in schizophrenia: modulating effects of sex and age. Am J Psychiatry. 2003 Dec; 160(12):2169-80. View in: PubMed

Sowell ER, Thompson PM, Welcome SE, Henkenius AL, Toga AW, Peterson BS. Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder. Lancet. 2003 Nov 22; 362(9397):1699-707. View in: PubMed

Pitiot A, Delingette H, Toga AW, Thompson PM. Learning object correspondences with the observed transport shape measure. Inf Process Med Imaging. 2003 Jul; 18:25-37. View in: PubMed

Gu X, Wang Y, Chan TF, Thompson PM, Yau ST. Genus zero surface conformal mapping and its application to brain surface mapping. Inf Process Med Imaging. 2003 Jul; 18:172-84. View in: PubMed

Lancaster JL, Kochunov PV, Thompson PM, Toga AW, Fox PT. Asymmetry of the brain surface from deformation field analysis. Hum Brain Mapp. 2003 Jun; 19(2):79-89. View in: PubMed

Sowell ER, Peterson BS, Thompson PM, Welcome SE, Henkenius AL, Toga AW. Mapping cortical change across the human life span. Nat Neurosci. 2003 Mar; 6(3):309-15. View in: PubMed

Ashburner J, Csernansky JG, Davatzikos C, Fox NC, Frisoni GB, Thompson PM. Computer-assisted imaging to assess brain structure in healthy and diseased brains. Lancet Neurol. 2003 Feb; 2(2):79-88. View in: PubMed

Thompson PM, Hayashi KM, de Zubicaray G, Janke AL, Rose SE, Semple J, Herman D, Hong MS, Dittmer SS, Doddrell DM, Toga AW. Dynamics of gray matter loss in Alzheimer's disease. J Neurosci. 2003 Feb 1; 23(3):994-1005. View in: PubMed

Zeineh MM, Engel SA, Thompson PM, Bookheimer SY. Dynamics of the hippocampus during encoding and retrieval of face-name pairs. Science. 2003 Jan 24; 299(5606):577-80. View in: PubMed

Toga AW, Thompson PM. Temporal dynamics of brain anatomy. Annu Rev Biomed Eng. 2003; 5:119-45. View in: PubMed

Toga AW, Thompson PM. Mapping brain asymmetry. Nat Rev Neurosci. 2003 Jan; 4(1):37-48. View in: PubMed

Sowell ER, Thompson PM, Peterson BS, Mattson SN, Welcome SE, Henkenius AL, Riley EP, Jernigan TL, Toga AW. Mapping cortical gray matter asymmetry patterns in adolescents with heavy prenatal alcohol exposure. Neuroimage. 2002 Dec; 17(4):1807-19. View in: PubMed

Narr KL, van Erp TG, Cannon TD, Woods RP, Thompson PM, Jang S, Blanton R, Poutanen VP, Huttunen M, Lönnqvist J, Standerksjöld-Nordenstam CG, Kaprio J, Mazziotta JC, Toga AW. A twin study of genetic contributions to hippocampal morphology in schizophrenia. Neurobiol Dis. 2002 Oct; 11(1):83-95. View in: PubMed

Pitiot A, Toga AW, Thompson PM. Adaptive elastic segmentation of brain MRI via shape-model-guided evolutionary programming. IEEE Trans Med Imaging. 2002 Aug; 21(8):910-23. View in: PubMed

Sowell ER, Thompson PM, Mattson SN, Tessner KD, Jernigan TL, Riley EP, Toga AW. Regional brain shape abnormalities persist into adolescence after heavy prenatal alcohol exposure. Cereb Cortex. 2002 Aug; 12(8):856-65. View in: PubMed

Narr KL, Cannon TD, Woods RP, Thompson PM, Kim S, Asunction D, van Erp TG, Poutanen VP, Huttunen M, Lönnqvist J, Standerksjöld-Nordenstam CG, Kaprio J, Mazziotta JC, Toga AW. Genetic contributions to altered callosal morphology in schizophrenia. J Neurosci. 2002 May 1; 22(9):3720-9. View in: PubMed

Cannon TD, Thompson PM, van Erp TG, Toga AW, Poutanen VP, Huttunen M, Lonnqvist J, Standerskjold-Nordenstam CG, Narr KL, Khaledy M, Zoumalan CI, Dail R, Kaprio J. Cortex mapping reveals regionally specific patterns of genetic and disease-specific gray-matter deficits in twins discordant for schizophrenia. Proc Natl Acad Sci U S A. 2002 Mar 5; 99(5):3228-33. View in: PubMed

Dinov ID, Mega MS, Thompson PM, Woods RP, Sumners DL, Sowell EL, Toga AW. Quantitative comparison and analysis of brain image registration using frequency-adaptive wavelet shrinkage. IEEE Trans Inf Technol Biomed. 2002 Mar; 6(1):73-85. View in: PubMed

Sowell ER, Thompson PM, Rex D, Kornsand D, Tessner KD, Jernigan TL, Toga AW. Mapping sulcal pattern asymmetry and local cortical surface gray matter distribution in vivo: maturation in perisylvian cortices. Cereb Cortex. 2002 Jan; 12(1):17-26. View in: PubMed

Toga AW, Thompson PM. New approaches in brain morphometry. Am J Geriatr Psychiatry. 2002 Jan-Feb; 10(1):13-23. View in: PubMed

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