Faculty

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Paulette Y. Mhawech-Fauceglia, MD
Professor of Clinical Pathology
Pathology
GNH 1100 North State Street Off Campus Los Angeles
+1 323 409 1313

Overview

After finishing her training in the United States and obtaining the American Board of clinical and anatomical Pathology, Dr. Fauceglia went back to Europe where she practiced Surgical Pathology in Geneva University Hospital an academic teaching institute for 4 years, concentrating on Uropathology and Gynecologic pathology. During her stay,she developed a special interest in urothelial bladder cancer and endometrial cancer.She was also involved in setting the research laboratory where she implemented and set up the tissue microarray technology (TMA).

Upon her return to the US, Dr. Fauceglia took a position at Roswell Park Cancer Institute (RPCI) where she concentrated mostly on gynecologic pathology. She has since helped the gynecologic-oncology service to become the best patient care service and was a referral pathologist to most of the Gynecologic cases for the community. During her work at RPCI, Dr. Fauceglia has succeeded in publishing numerous manuscripts, most of which are in translational research. She also heavily supports the gynecology-oncology research program and the vaccine trial program headed by Dr. Kunle Odunsi at RPCI.

At the present time at USC, Dr. Fauceglia had numerous collaborative research projects with Dr. Simon Gaythner and his team in preventive medicine studying the gene profiling of ovarian cancer. As well as with the Gyn-Oncologic research team guided by Dr.yvonne Lin

Publications

Tierney KE, Ji L, Dralla SS, Yoo E, Yessaian A, Pham HQ, Roman L, Sposto R, Mhawech-Fauceglia P, Lin YG. Endoplasmic reticulum stress in complex atypical hyperplasia as a possible predictor of occult carcinoma and progestin response. Gynecol Oncol. 2016 Oct 19. View in: PubMed

Mhawech-Fauceglia P, Ramzan A, Walia S, Pham HQ, Yessaian A. Microfocus of Anaplastic Carcinoma Arising in Mural Nodule of Ovarian Mucinous Borderline Tumor With Very Rapid and Fatal Outcome. Int J Gynecol Pathol. 2016 Jul; 35(4):348-51. View in: PubMed

Hope ER, Mhawech-Fauceglia P, Pejovic T, Zahn CM, Wang G, Conrads TP, Larry Maxwell G, Hamilton CA, Darcy KM, Syed V. Nestin: A biomarker of aggressive uterine cancers. Gynecol Oncol. 2016 Mar; 140(3):503-11. View in: PubMed

Manek R, Pakzamir E, Mhawech-Fauceglia P, Pejovic T, Sowter H, Gayther SA, Lawrenson K. Targeting Src in endometriosis-associated ovarian cancer. Oncogenesis. 2016; 5(8):e251. View in: PubMed

Chimge NO, Little GH, Baniwal SK, Adisetiyo H, Xie Y, Zhang T, O'Laughlin A, Liu ZY, Ulrich P, Martin A, Mhawech-Fauceglia P, Ellis MJ, Tripathy D, Groshen S, Liang C, Li Z, Schones DE, Frenkel B. RUNX1 prevents oestrogen-mediated AXIN1 suppression and ß-catenin activation in ER-positive breast cancer. Nat Commun. 2016; 7:10751. View in: PubMed

Zhang W, Barger CJ, Link PA, Mhawech-Fauceglia P, Miller A, Akers SN, Odunsi K, Karpf AR. DNA hypomethylation-mediated activation of Cancer/Testis Antigen 45 (CT45) genes is associated with disease progression and reduced survival in epithelial ovarian cancer. Epigenetics. 2015 Aug 3; 10(8):736-48. View in: PubMed

Kim G, Pham HQ, Ramzan A, Elishaev E, Mhawech-Fauceglia P. Endometrioid adenocarcinoma associated with endometrial stromal sarcoma: A rare, often unrecognized collision tumor. Gynecol Oncol Rep. 2015 Aug; 13:8-12. View in: PubMed

Matsuo K, Tierney KE, Schneider DM, Mhawech-Fauceglia P, Roman LD, Gershenson DM. Characteristics of ovarian tumors of low malignant potential in BRCA mutation carriers: A case series. Gynecol Oncol Rep. 2015 Aug; 13:36-9. View in: PubMed

Matsuo K, Ramzan AA, Gualtieri MR, Mhawech-Fauceglia P, Machida H, Moeini A, Dancz CE, Ueda Y, Roman LD. Prediction of concurrent endometrial carcinoma in women with endometrial hyperplasia. Gynecol Oncol. 2015 Jul 31. View in: PubMed

Adler E, Mhawech-Fauceglia P, Gayther SA, Lawrenson K. PAX8 expression in ovarian surface epithelial cells. Hum Pathol. 2015 Jul; 46(7):948-56. View in: PubMed

Hwang H, Matsuo K, Duncan K, Pakzamir E, Pham HQ, Correa A, Fedenko A, Mhawech-Fauceglia P. Immunohistochemical panel to differentiate endometrial stromal sarcoma, uterine leiomyosarcoma and leiomyoma: something old and something new. J Clin Pathol. 2015 May 19. View in: PubMed

Mhawech-Fauceglia P. MOLECULAR FINGERPRINTS OF MIXED ENDOMETRIOID AND SEROUS ADENOCARCINOMA OF THE ENDOMETRIUM: IGCS-0044 Uterine Cancer, including Sarcoma. Int J Gynecol Cancer. 2015 May; 25 Suppl 1:68. View in: PubMed

Mhawech-Fauceglia P, Yan L, Sharifian M, Ren X, Liu S, Kim G, Gayther SA, Pejovic T, Lawrenson K. Stromal Expression of Fibroblast Activation Protein Alpha (FAP) Predicts Platinum Resistance and Shorter Recurrence in patients with Epithelial Ovarian Cancer. Cancer Microenviron. 2015 Apr; 8(1):23-31. View in: PubMed

Lawrenson K, Grun B, Lee N, Mhawech-Fauceglia P, Kan J, Swenson S, Lin YG, Pejovic T, Millstein J, Gayther SA. NPPB is a novel candidate biomarker expressed by cancer-associated fibroblasts in epithelial ovarian cancer. Int J Cancer. 2015 Mar 15; 136(6):1390-401. View in: PubMed

Lin YG, Shen J, Yoo E, Liu R, Yen HY, Mehta A, Rajaei A, Yang W, Mhawech-Fauceglia P, DeMayo FJ, Lydon J, Gill P, Lee AS. Targeting the glucose-regulated protein-78 abrogates Pten-null driven AKT activation and endometrioid tumorigenesis. Oncogene. 2015 Feb 16. View in: PubMed

Lawrenson K, Pakzamir E, Liu B, Lee JM, Delgado MK, Duncan K, Gayther SA, Liu S, Roman L, Mhawech-Fauceglia P. Molecular Analysis of Mixed Endometrioid and Serous Adenocarcinoma of the Endometrium. PLoS One. 2015; 10(7):e0130909. View in: PubMed

Lawrenson K, Mhawech-Fauceglia P, Worthington J, Spindler TJ, O'Brien D, Lee JM, Spain G, Sharifian M, Wang G, Darcy KM, Pejovic T, Sowter H, Timms JF, Gayther SA. Identification of novel candidate biomarkers of epithelial ovarian cancer by profiling the Secretomes of three-dimensional genetic models of ovarian carcinogenesis. Int J Cancer. 2014 Sep 9. View in: PubMed

Mhawech-Fauceglia P, Wang D, Samrao D, Kim G, Lawrenson K, Meneses T, Liu S, Yessaian A, Pejovic T. Clinical Implications of Marker Expression of Carcinoma-Associated Fibroblasts (CAFs) in Patients with Epithelial Ovarian Carcinoma After Treatment with Neoadjuvant Chemotherapy. Cancer Microenviron. 2014 Aug; 7(1-2):33-9. View in: PubMed

Mhawech-Fauceglia P, Wang D, Kim G, Sharifian M, Chen X, Liu Q, Lin YG, Liu S, Pejovic T. Expression of DNA repair proteins in endometrial cancer predicts disease outcome. Gynecol Oncol. 2014 Mar; 132(3):593-8. View in: PubMed

Daudi S, Eng KH, Mhawech-Fauceglia P, Morrison C, Miliotto A, Beck A, Matsuzaki J, Tsuji T, Groman A, Gnjatic S, Spagnoli G, Lele S, Odunsi K. Expression and Immune Responses to MAGE Antigens Predict Survival in Epithelial Ovarian Cancer. PLoS One. 2014; 9(8):e104099. View in: PubMed

Liao J, Qian F, Tchabo N, Mhawech-Fauceglia P, Beck A, Qian Z, Wang X, Huss WJ, Lele SB, Morrison CD, Odunsi K. Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties Contribute to Tumor Generation, Metastasis and Chemotherapy Resistance through Hypoxia-Resistant Metabolism. PLoS One. 2014; 9(1):e84941. View in: PubMed

Odunsi K, Matsuzaki J, James SR, Mhawech-Fauceglia P, Tsuji T, Miller A, Zhang W, Akers SN, Griffiths EA, Miliotto A, Beck A, Batt CA, Ritter G, Lele S, Gnjatic S, Karpf AR. Epigenetic potentiation of NY-ESO-1 vaccine therapy in human ovarian cancer. Cancer Immunol Res. 2014 Jan 1; 2(1):37-49. View in: PubMed

Godoy H, Mhawech-Fauceglia P, Beck A, Miliotto A, Miller A, Lele S, Odunsi K. Developmentally restricted differentiation antigens are targets for immunotherapy in epithelial ovarian carcinoma. Int J Gynecol Pathol. 2013 Nov; 32(6):536-40. View in: PubMed

Gray MJ, Mhawech-Fauceglia P, Yoo E, Yang W, Wu E, Lee AS, Lin YG. AKT inhibition mitigates GRP78 (glucose-regulated protein) expression and contribution to chemoresistance in endometrial cancers. Int J Cancer. 2013 Jul; 133(1):21-30. View in: PubMed

Mhawech-Fauceglia P, Wang D, Samrao D, Liu S, DuPont NC, Pejovic T. Trefoil factor family 3 (TFF3) expression and its interaction with estrogen receptor (ER) in endometrial adenocarcinoma. Gynecol Oncol. 2013 Jul; 130(1):174-80. View in: PubMed

Mhawech-Fauceglia P, Yan L, Liu S, Pejovic T. ER+ /PR+ /TFF3+ /IMP3- immunoprofile distinguishes endometrioid from serous and clear cell carcinomas of the endometrium: a study of 401 cases. Histopathology. 2013 Jun; 62(7):976-85. View in: PubMed

Lee JM, Mhawech-Fauceglia P, Lee N, Parsanian LC, Lin YG, Gayther SA, Lawrenson K. A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro. Lab Invest. 2013 May; 93(5):528-42. View in: PubMed

Dandapani SV, Mhawech-Fauceglia P, Palmer S, Senikowich M, Lin YG. Lower extremity pain as initial presentation of cervical cancer. Gynecol Oncol Case Rep. 2013; 5:13-5. View in: PubMed

Mhawech-Fauceglia P, Kay B, Li CJ, Lin YG. Metastatic ovarian papillary serous carcinoma to the breast: Diagnosis and pitfalls. Gynecol Oncol Case Rep. 2013; 4:35-7. View in: PubMed

Tierney KE, Rogers A, Mhawech-Fauceglia P, Lin YG. Recurrent leiomyosarcoma presenting as malignant arterial tumor thrombus. Gynecol Oncol Case Rep. 2013; 4:32-4. View in: PubMed

Mhawech-Fauceglia P, Wang D, Ali L, Lele S, Huba MA, Liu S, Odunsi K. Intraepithelial T cells and tumor-associated macrophages in ovarian cancer patients. Cancer Immun. 2013; 13:1. View in: PubMed

Samrao D, Wang D, Ough F, Lin YG, Liu S, Menesses T, Yessaian A, Turner N, Pejovic T, Mhawech-Fauceglia P. Histologic parameters predictive of disease outcome in women with advanced stage ovarian carcinoma treated with neoadjuvant chemotherapy. Transl Oncol. 2012 Dec; 5(6):469-74. View in: PubMed

Syriac S, Kesterson J, Izevbaye I, de Mesy Bentley KL, Lele S, Mhawech-Fauceglia P. Clinically aggressive primary solid pseudopapillary tumor of the ovary in a 45-year-old woman. Ann Diagn Pathol. 2012 Dec; 16(6):498-503. View in: PubMed

Mhawech-Fauceglia P, Wang D, Samrao D, Godoy H, Ough F, Liu S, Pejovic T, Lele S. Pair Box 8 (PAX8) protein expression in high grade, late stage (stages III and IV) ovarian serous carcinoma. Gynecol Oncol. 2012 Oct; 127(1):198-201. View in: PubMed

Mhawech-Fauceglia P, Wang D, Samrao D, Godoy H, Pejovic T, Liu S, Lele S. Pair-Box (PAX8) protein-positive expression is associated with poor disease outcome in women with endometrial cancer. Br J Cancer. 2012 Jul 10; 107(2):370-4. View in: PubMed

Mhawech-Fauceglia P, Wang D, Menesses T, Chandavarkar U, Ough F, Lin Y, Liu S. Pax-8 is a reliable marker in making the diagnosis in advanced stage epithelial ovarian carcinoma and primary peritoneal carcinoma for neoadjuvant chemotherapy on cell block and biopsy specimens. Histopathology. 2012 May; 60(6):1019-20. View in: PubMed

Odunsi K, Matsuzaki J, Karbach J, Neumann A, Mhawech-Fauceglia P, Miller A, Beck A, Morrison CD, Ritter G, Godoy H, Lele S, Dupont N, Edwards R, Shrikant P, Old LJ, Gnjatic S, Jäger E. Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients. Proc Natl Acad Sci U S A. 2012 Apr 10; 109(15):5797-802. View in: PubMed

Mhawech-Fauceglia P, Wang D, Lele S, Frederick PJ, Pejovic T, Liu S. Claudin7 and moesin in endometrial Adenocarcinoma; a retrospective study of 265 patients. BMC Res Notes. 2012; 5:65. View in: PubMed

Wysham WZ, Mhawech-Fauceglia P, Li H, Hays L, Syriac S, Skrepnik T, Wright J, Pande N, Hoatlin M, Pejovic T. BRCAness Profile of Sporadic Ovarian Cancer Predicts Disease Recurrence. PLoS One. 2012; 7(1):e30042. View in: PubMed

Mhawech-Fauceglia P, Wang D, Syriac S, Godoy H, Dupont N, Liu S, Odunsi K. Synuclein-? (SNCG) protein expression is associated with poor outcome in endometrial adenocarcinoma. Gynecol Oncol. 2012 Jan; 124(1):148-52. View in: PubMed

Mhawech-Fauceglia P, Afkhami M, Pejovic T. MET/HGF Signaling Pathway in Ovarian Carcinoma: Clinical Implications and Future Direction. Patholog Res Int. 2012; 2012:960327. View in: PubMed

Odunsi K, Mhawech-Fauceglia P, Andrews C, Beck A, Amuwo O, Lele S, Black JD, Huang RY. Elevated expression of the serine-arginine protein kinase 1 gene in ovarian cancer and its role in Cisplatin cytotoxicity in vitro. PLoS One. 2012; 7(12):e51030. View in: PubMed

Mhawech-Fauceglia P, Wang D, Samrao D, Menesses T, Godoy H, Ough F, Lele S, Liu S, Pejovic T. The role of hypoxic-inducible factor (HIF1a) and aldolaseC protein in endometrial carcinogenesis: a retrospective study of 279 patients. BMJ Open. 2012; 2(4). View in: PubMed

Mhawech-Fauceglia P, Wang D, Kesterson J, Beck A, de Mesy Bentley KL, Shroff S, Syriac S, Frederick P, Liu S, Odunsi K. Aldolase mRNA expression in endometrial cancer and the role of clotrimazole in endometrial cancer cell viability and morphology. Histopathology. 2011 Nov; 59(5):1015-8. View in: PubMed

Kanis M, Kesterson JP, Shroff S, Lele S, Mhawech-Fauceglia P. Malignant mixed müllerian tumor of primary peritoneal origin. Ann Diagn Pathol. 2011 Aug; 15(4):273-7. View in: PubMed

Mhawech-Fauceglia P, Kesterson J, Wang D, Akers S, Dupont NC, Clark K, Lele S, Liu S. Expression and clinical significance of the transforming growth factor-ß signalling pathway in endometrial cancer. Histopathology. 2011 Jul; 59(1):63-72. View in: PubMed

Syriac S, Durie N, Kesterson J, Lele S, Mhawech-Fauceglia P. Female adnexal tumor of probable Wolffian origin (FATWO) with recurrence 3 years postsurgery. Int J Gynecol Pathol. 2011 May; 30(3):231-5. View in: PubMed

Woloszynska-Read A, Zhang W, Yu J, Link PA, Mhawech-Fauceglia P, Collamat G, Akers SN, Ostler KR, Godley LA, Odunsi K, Karpf AR. Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage. Clin Cancer Res. 2011 Apr 15; 17(8):2170-80. View in: PubMed

Godoy H, Mhawech-Fauceglia P, Beck A, Miller A, Lele S, Odunsi K. Expression of poly (adenosine diphosphate-ribose) polymerase and p53 in epithelial ovarian cancer and their role in prognosis and disease outcome. Int J Gynecol Pathol. 2011 Mar; 30(2):139-44. View in: PubMed

Mhawech-Fauceglia P, Wang D, Kesterson J, Syriac S, Clark K, Frederick PJ, Lele S, Liu S. Gene expression profiles in stage I uterine serous carcinoma in comparison to grade 3 and grade 1 stage I endometrioid adenocarcinoma. PLoS One. 2011; 6(3):e18066. View in: PubMed

Mhawech-Fauceglia P, Herrmann RF, Kesterson J, Izevbaye I, Lele S, Odunsi K. Prognostic factors in stages II/III/IV and stages III/IV endometrioid and serous adenocarcinoma of the endometrium. Eur J Surg Oncol. 2010 Dec; 36(12):1195-201. View in: PubMed

Batt RE, Mhawech-Fauceglia P, Odunsi K, Yeh J. Pathogenesis of mediastinal paravertebral müllerian cysts of Hattori: developmental endosalpingiosis-müllerianosis. Int J Gynecol Pathol. 2010 Nov; 29(6):546-51. View in: PubMed

Mhawech-Fauceglia P, Herrmann FR, Rai H, Tchabo N, Lele S, Izevbaye I, Odunsi K, Cheney RT. IMP3 distinguishes uterine serous carcinoma from endometrial endometrioid adenocarcinoma. Am J Clin Pathol. 2010 Jun; 133(6):899-908. View in: PubMed

Ali L, Bambach BJ, Kozielski R, Wagner H, Lele S, Mhawech-Fauceglia P. Ovarian yolk sac tumor associated with major fibrosarcoma component in a 13-year-old girl. Int J Gynecol Pathol. 2010 May; 29(3):252-5. View in: PubMed

Matsuzaki J, Gnjatic S, Mhawech-Fauceglia P, Beck A, Miller A, Tsuji T, Eppolito C, Qian F, Lele S, Shrikant P, Old LJ, Odunsi K. Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer. Proc Natl Acad Sci U S A. 2010 Apr 27; 107(17):7875-80. View in: PubMed

Paczos TA, Ackers S, Odunsi K, Lele S, Mhawech-Fauceglia P. Primary vaginal adenocarcinoma arising in vaginal adenosis after CO2 laser vaporization and 5-fluorouracil therapy. Int J Gynecol Pathol. 2010 Mar; 29(2):193-6. View in: PubMed

Mhawech-Fauceglia P, Wang D, Kesterson J, Clark K, Monhollen L, Odunsi K, Lele S, Liu S. Microarray analysis reveals distinct gene expression profiles among different tumor histology, stage and disease outcomes in endometrial adenocarcinoma. PLoS One. 2010; 5(11):e15415. View in: PubMed

Pejovic T, Pande NT, Mori M, Mhawech-Fauceglia P, Harrington C, Mongoue-Tchokote S, Dim D, Andrews C, Beck A, Tarumi Y, Djilas J, Cappuccini F, Caballero O, Huang J, Levy S, Tsiamouri A, Cain J, Bagby GC, Strausberg RL, Simpson AJ, Odunsi KO. Expression profiling of the ovarian surface kinome reveals candidate genes for early neoplastic changes. Transl Oncol. 2009 Dec; 2(4):341-9. View in: PubMed

Mhawech-Fauceglia P, Herrmann FR, Wagner H, Godoy H, Odunsi K, Cheney RT, Lele S. Submission of the entire lymph node dissection for histologic examination in gynecologic-oncologic specimens. Clinical and pathologic relevance. Gynecol Oncol. 2009 Dec; 115(3):354-6. View in: PubMed

Mhawech-Fauceglia P, Chan A, Keitz B, Lele S, Cheney RT, Starostik P. Microsatellite instability in large cell neuroendocrine carcinoma of the female genital tract. Histopathology. 2009 Nov; 55(5):621-5. View in: PubMed

Tchabo NE, McCloskey S, Mashtare TL, Andrews C, Singh AK, Mhawech-Fauceglia P, Odunsi K, Lele S, Jaggernauth W. Treatment of early-stage uterine papillary serous carcinoma at Roswell Park Cancer Institute, 1992-2006. Gynecol Oncol. 2009 Nov; 115(2):249-56. View in: PubMed

Mhawech-Fauceglia P, Ali L, Cheney RT, Groth J, Herrmann FR. Prognostic significance of neuron-associated protein expression in non-muscle-invasive urothelial bladder cancer. J Clin Pathol. 2009 Aug; 62(8):710-4. View in: PubMed

Qian F, Villella J, Wallace PK, Mhawech-Fauceglia P, Tario JD, Andrews C, Matsuzaki J, Valmori D, Ayyoub M, Frederick PJ, Beck A, Liao J, Cheney R, Moysich K, Lele S, Shrikant P, Old LJ, Odunsi K. Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T-cell proliferation in human epithelial ovarian cancer. Cancer Res. 2009 Jul 1; 69(13):5498-504. View in: PubMed

Mhawech-Fauceglia P, Herrmann FR, Andrews C, South S, Beck A, Lele S, Odunsi K. 14-3-3sigma expression and prognostic value in patients with epithelial ovarian carcinoma: a high throughput tissue microarray analysis. Eur J Surg Oncol. 2009 Jul; 35(7):763-7. View in: PubMed

Paonessa JD, Munday CM, Mhawech-Fauceglia P, Munday R, Zhang Y. 5,6-Dihydrocyclopenta[c][1,2]-dithiole-3(4H)-thione is a promising cancer chemopreventive agent in the urinary bladder. Chem Biol Interact. 2009 Jun 15; 180(1):119-26. View in: PubMed

Chen YT, Hsu M, Lee P, Shin SJ, Mhawech-Fauceglia P, Odunsi K, Altorki NK, Song CJ, Jin BQ, Simpson AJ, Old LJ. Cancer/testis antigen CT45: analysis of mRNA and protein expression in human cancer. Int J Cancer. 2009 Jun 15; 124(12):2893-8. View in: PubMed

Sood AK, Wang J, Mhawech-Fauceglia P, Jana B, Liang P, Geradts J. Sam-pointed domain containing Ets transcription factor in luminal breast cancer pathogenesis. Cancer Epidemiol Biomarkers Prev. 2009 Jun; 18(6):1899-903. View in: PubMed

Rai H, Odunsi K, Kesterson J, Morrison C, Chan A, Mhawech-Fauceglia P. Epithelioid sarcoma of the vulva in a 17-year-old pregnant woman. Appl Immunohistochem Mol Morphol. 2009 May; 17(3):270-3. View in: PubMed

Tebeu PM, Petignat P, Mhawech-Fauceglia P. Gynecological malignancies in Maroua, Cameroon. Int J Gynaecol Obstet. 2009 Feb; 104(2):148-9. View in: PubMed

Tchabo NE, Mhawech-Fauceglia P, Caballero OL, Villella J, Beck AF, Miliotto AJ, Liao J, Andrews C, Lele S, Old LJ, Odunsi K. Expression and serum immunoreactivity of developmentally restricted differentiation antigens in epithelial ovarian cancer. Cancer Immun. 2009; 9:6. View in: PubMed

Kesterson JP, Mhawech-Fauceglia P, Lele S. The use of bevacizumab in refractory ovarian granulosa-cell carcinoma with symptomatic relief of ascites: a case report. Gynecol Oncol. 2008 Dec; 111(3):527-9. View in: PubMed

Mhawech-Fauceglia P, Allal A, Odunsi K, Andrews C, Herrmann FR, Huard B. Role of the tumour necrosis family ligand APRIL in solid tumour development: Retrospective studies in bladder, ovarian and head and neck carcinomas. Eur J Cancer. 2008 Oct; 44(15):2097-100. View in: PubMed

Mhawech-Fauceglia P, Odunsi K, Dim D, Nowak N, Lele S, Cheney RT, Pejovic T. Array-comparative genomic hybridization analysis of primary endometrial and ovarian high-grade neuroendocrine carcinoma associated with adenocarcinoma: mystery resolved? Int J Gynecol Pathol. 2008 Oct; 27(4):539-46. View in: PubMed

Mhawech-Fauceglia P, Rai H, Nowak N, Cheney RT, Rodabaugh K, Lele S, Odunsi K. The use of array-based comparative genomic hybridization (a-CGH) to distinguish metastatic from primary synchronous carcinomas of the ovary and the uterus. Histopathology. 2008 Oct; 53(4):490-5. View in: PubMed

Mhawech-Fauceglia P, Herrmann FR, Chan A, Cheney RT, Zhang Y. No association of NAD(P)H quinone oxidoreductase 1 expression with p53 expression or tumour outcome in patients with superficial and minimally invasive urothelial bladder cancers. BJU Int. 2008 Aug 5; 102(5):639. View in: PubMed

Mhawech-Fauceglia P, Herrmann F, Bshara W, Zhang S, Penetrante R, Lele S, Odunsi K, Rodabaugh K. Intraobserver and interobserver variability in distinguishing between endocervical and endometrial adenocarcinoma on problematic cases of cervical curettings. Int J Gynecol Pathol. 2008 Jul; 27(3):431-6. View in: PubMed

Tebeu PM, Major AL, Rapiti E, Petignat P, Bouchardy C, Sando Z, de Bernis L, Ali L, Mhawech-Fauceglia P. The attitude and knowledge of cervical cancer by Cameroonian women; a clinical survey conducted in Maroua, the capital of Far North Province of Cameroon. Int J Gynecol Cancer. 2008 Jul-Aug; 18(4):761-5. View in: PubMed

Mhawech-Fauceglia P, Alvarez V, Fischer G, Beck A, Herrmann FR. Association of TSC1/hamartin, 14-3-3sigma, and p27 expression with tumor outcomes in patients with pTa/pT1 urothelial bladder carcinoma. Am J Clin Pathol. 2008 Jun; 129(6):918-23. View in: PubMed

Woloszynska-Read A, Mhawech-Fauceglia P, Yu J, Odunsi K, Karpf AR. Intertumor and intratumor NY-ESO-1 expression heterogeneity is associated with promoter-specific and global DNA methylation status in ovarian cancer. Clin Cancer Res. 2008 Jun 1; 14(11):3283-90. View in: PubMed

Mhawech-Fauceglia P, Pejovic T, Dim D, Fang X, Conroy J, Lele S, Cheney R, Odunsi K. Array-based comparative genomic hybridization (aCGH) analysis is a useful tool for distinguishing primary pulmonary from metastatic neuroendocrine carcinoma to the lung. Appl Immunohistochem Mol Morphol. 2008 May; 16(3):291-5. View in: PubMed

Munday R, Mhawech-Fauceglia P, Munday CM, Paonessa JD, Tang L, Munday JS, Lister C, Wilson P, Fahey JW, Davis W, Zhang Y. Inhibition of urinary bladder carcinogenesis by broccoli sprouts. Cancer Res. 2008 Mar 1; 68(5):1593-600. View in: PubMed

Mhawech-Fauceglia P, Smiraglia DJ, Bshara W, Andrews C, Schwaller J, South S, Higgs D, Lele S, Herrmann F, Odunsi K. Prostate-specific membrane antigen expression is a potential prognostic marker in endometrial adenocarcinoma. Cancer Epidemiol Biomarkers Prev. 2008 Mar; 17(3):571-7. View in: PubMed

Tchabo NE, Mhawech-Fauceglia P, Lele S. Primary squamous cell carcinoma of the endometrium: a case report. Eur J Gynaecol Oncol. 2008; 29(5):527-30. View in: PubMed

Fang X, Rodabaugh K, Penetrante R, Wong M, Wagner T, Sait S, Mhawech-Fauceglia P. Desmoplastic small round cell tumor (DSRCT) with ovarian involvement in 2 young women. Appl Immunohistochem Mol Morphol. 2008 Jan; 16(1):94-9. View in: PubMed

Mhawech-Fauceglia P, Fischer G, Alvarez V, Ahmed A, Herrmann FR. Predicting outcome in minimally invasive (T1a and T1b) urothelial bladder carcinoma using a panel of biomarkers: a high throughput tissue microarray analysis. BJU Int. 2007 Nov; 100(5):1182-7. View in: PubMed

Sharma S, Tammela J, Wang X, Arnouk H, Driscoll D, Mhawech-Fauceglia P, Lele S, Kazim AL, Odunsi K. Characterization of a putative ovarian oncogene, elongation factor 1alpha, isolated by panning a synthetic phage display single-chain variable fragment library with cultured human ovarian cancer cells. Clin Cancer Res. 2007 Oct 1; 13(19):5889-96. View in: PubMed

Nowak NJ, Miecznikowski J, Moore SR, Gaile D, Bobadilla D, Smith DD, Kernstine K, Forman SJ, Mhawech-Fauceglia P, Reid M, Stoler D, Loree T, Rigual N, Sullivan M, Weiss LM, Hicks D, Slovak ML. Challenges in array comparative genomic hybridization for the analysis of cancer samples. Genet Med. 2007 Sep; 9(9):585-95. View in: PubMed

South SA, Hutton M, Farrell C, Mhawech-Fauceglia P, Rodabaugh KJ. Uterine carcinosarcoma associated with hereditary nonpolyposis colorectal cancer. Obstet Gynecol. 2007 Aug; 110(2 Pt 2):543-5. View in: PubMed

Odunsi K, Qian F, Matsuzaki J, Mhawech-Fauceglia P, Andrews C, Hoffman EW, Pan L, Ritter G, Villella J, Thomas B, Rodabaugh K, Lele S, Shrikant P, Old LJ, Gnjatic S. Vaccination with an NY-ESO-1 peptide of HLA class I/II specificities induces integrated humoral and T cell responses in ovarian cancer. Proc Natl Acad Sci U S A. 2007 Jul 31; 104(31):12837-42. View in: PubMed

Mhawech-Fauceglia P, Ramzy P, Bshara W, Sait S, Rigual N. Synovial sarcoma of the larynx in a 79-year-old woman, confirmed by karyotyping and fluorescence in situ hybridization analysis. Ann Diagn Pathol. 2007 Jun; 11(3):223-7. View in: PubMed

Mhawech-Fauceglia P, Herrmann FR, Bshara W, Odunsi K, Terracciano L, Sauter G, Cheney RT, Groth J, Penetrante R, Mhawech-Fauceglia P. Friend leukaemia integration-1 expression in malignant and benign tumours: a multiple tumour tissue microarray analysis using polyclonal antibody. J Clin Pathol. 2007 Jun; 60(6):694-700. View in: PubMed

Mhawech-Fauceglia P, Saxena R, Zhang S, Terracciano L, Sauter G, Chadhuri A, Herrmann FR, Penetrante R. Pax-5 immunoexpression in various types of benign and malignant tumours: a high-throughput tissue microarray analysis. J Clin Pathol. 2007 Jun; 60(6):709-14. View in: PubMed

Schwaller J, Went P, Matthes T, Dirnhofer S, Donze O, Mhawech-Fauceglia P, Myit S, Huard B. Paracrine promotion of tumor development by the TNF ligand APRIL in Hodgkin's Disease. Leukemia. 2007 Jun; 21(6):1324-7. View in: PubMed

Villella J, Herrmann FR, Kaul S, Lele S, Marchetti D, Natiella J, Odunsi K, Mhawech-Fauceglia P. Clinical and pathological predictive factors in women with adult-type granulosa cell tumor of the ovary. Int J Gynecol Pathol. 2007 Apr; 26(2):154-9. View in: PubMed

Mhawech-Fauceglia P, Zhang S, Terracciano L, Sauter G, Chadhuri A, Herrmann FR, Penetrante R. Prostate-specific membrane antigen (PSMA) protein expression in normal and neoplastic tissues and its sensitivity and specificity in prostate adenocarcinoma: an immunohistochemical study using mutiple tumour tissue microarray technique. Histopathology. 2007 Mar; 50(4):472-83. View in: PubMed

Mhawech-Fauceglia P, Dulguerov P, Beck A, Bonet M, Allal AS. Value of ezrin, maspin and nm23-H1 protein expressions in predicting outcome of patients with head and neck squamous-cell carcinoma treated with radical radiotherapy. J Clin Pathol. 2007 Feb; 60(2):185-9. View in: PubMed

Schwaller J, Schneider P, Mhawech-Fauceglia P, McKee T, Myit S, Matthes T, Tschopp J, Donze O, Le Gal FA, Huard B. Neutrophil-derived APRIL concentrated in tumor lesions by proteoglycans correlates with human B-cell lymphoma aggressiveness. Blood. 2007 Jan 1; 109(1):331-8. View in: PubMed

Rodabaugh KJ, Mhawech-Fauceglia P, Groth J, Lele S, Sood AK. Prostate-derived Ets factor is overexpressed in serous epithelial ovarian tumors. Int J Gynecol Pathol. 2007 Jan; 26(1):10-5. View in: PubMed

Zhang Y, Munday R, Jobson HE, Munday CM, Lister C, Wilson P, Fahey JW, Mhawech-Fauceglia P. Induction of GST and NQO1 in cultured bladder cells and in the urinary bladders of rats by an extract of broccoli (Brassica oleracea italica) sprouts. J Agric Food Chem. 2006 Dec 13; 54(25):9370-6. View in: PubMed

Mhawech-Fauceglia P, Herrmann F, Penetrante R, Beck A, Sait S, Block AM, Odunsi K, Fisher J, Balos L, Cheney RT. Diagnostic utility of FLI-1 monoclonal antibody and dual-colour, break-apart probe fluorescence in situ (FISH) analysis in Ewing's sarcoma/primitive neuroectodermal tumour (EWS/PNET). A comparative study with CD99 and FLI-1 polyclonal antibodies. Histopathology. 2006 Dec; 49(6):569-75. View in: PubMed

Saxena R, Sait S, Mhawech-Fauceglia P. Ewing sarcoma/primitive neuroectodermal tumor of the kidney: a case report. Diagnosed by immunohistochemistry and molecular analysis. Ann Diagn Pathol. 2006 Dec; 10(6):363-6. View in: PubMed

Mhawech-Fauceglia P, Kaya G, Sauter G, McKee T, Donze O, Schwaller J, Huard B. The source of APRIL up-regulation in human solid tumor lesions. J Leukoc Biol. 2006 Oct; 80(4):697-704. View in: PubMed

Tammela J, Uenaka A, Ono T, Noguchi Y, Jungbluth AA, Mhawech-Fauceglia P, Qian F, Schneider S, Sharma S, Driscoll D, Lele S, Old LJ, Nakayama E, Odunsi K. OY-TES-1 expression and serum immunoreactivity in epithelial ovarian cancer. Int J Oncol. 2006 Oct; 29(4):903-10. View in: PubMed

Tebeu PM, Major AL, Mhawech P, Rapiti E. The recurrence of cervical intraepithelial neoplasia in HIV-positive women: a review of the literature. Int J STD AIDS. 2006 Aug; 17(8):507-11. View in: PubMed

Mhawech-Fauceglia P, Fischer G, Beck A, Cheney RT, Herrmann FR. Raf1, Aurora-A/STK15 and E-cadherin biomarkers expression in patients with pTa/pT1 urothelial bladder carcinoma; a retrospective TMA study of 246 patients with long-term follow-up. Eur J Surg Oncol. 2006 May; 32(4):439-44. View in: PubMed

Fischer G, Odunsi K, Lele S, Mhawech P. Ovarian primary primitive neurectodermal tumor coexisting with endometrioid adenocarcinoma: a case report. Int J Gynecol Pathol. 2006 Apr; 25(2):151-4. View in: PubMed

Mhawech-Fauceglia P, Cheney RT, Schwaller J. Genetic alterations in urothelial bladder carcinoma: an updated review. Cancer. 2006 Mar 15; 106(6):1205-16. View in: PubMed

Mhawech-Fauceglia P, Oberholzer M, Aschenafi S, Baur A, Kurrer M, Von Rohr A, Hsu-Schmitz SF, Wagner B, Delacretaz F, Hurwitz N. Potential predictive patterns of minimal residual disease detected by immunohistochemistry on bone marrow biopsy specimens during a long-term follow-up in patients treated with cladribine for hairy cell leukemia. Arch Pathol Lab Med. 2006 Mar; 130(3):374-7. View in: PubMed

Mhawech-Fauceglia P, Cheney RT, Fischer G, Beck A, Herrmann FR. FGFR3 and p53 protein expressions in patients with pTa and pT1 urothelial bladder cancer. Eur J Surg Oncol. 2006 Mar; 32(2):231-7. View in: PubMed

Giger R, Mhawech P, Marchal F, Lehmann W, Dulguerov P. Mucoepidermoid carcinoma of Stensen's duct: a case report and review of the literature. Head Neck. 2005 Sep; 27(9):829-33. View in: PubMed

Mhawech P. 14-3-3 proteins--an update. Cell Res. 2005 Apr; 15(4):228-36. View in: PubMed

Ho L, Davis RE, Conne B, Chappuis R, Berczy M, Mhawech P, Staudt LM, Schwaller J. MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-kappa B-dependent proliferative advantage and resistance against FAS-induced cell death in B cells. Blood. 2005 Apr 1; 105(7):2891-9. View in: PubMed

Mhawech P, Benz A, Cerato C, Greloz V, Assaly M, Desmond JC, Koeffler HP, Lodygin D, Hermeking H, Herrmann F, Schwaller J. Downregulation of 14-3-3sigma in ovary, prostate and endometrial carcinomas is associated with CpG island methylation. Mod Pathol. 2005 Mar; 18(3):340-8. View in: PubMed

Mhawech P, Greloz V, Assaly M, Herrmann F. Immunohistochemical expression of 14-3-3 sigma protein in human urological and gynecological tumors using a multi-tumor microarray analysis. Pathol Int. 2005 Feb; 55(2):77-82. View in: PubMed

Mhawech P, Dulguerov P, Assaly M, Ares C, Allal AS. EB-D fibronectin expression in squamous cell carcinoma of the head and neck. Oral Oncol. 2005 Jan; 41(1):82-8. View in: PubMed

Mhawech P, Berczy M, Assaly M, Herrmann F, Bouzourene H, Allal AS, Dulguerov P, Schwaller J. Human achaete-scute homologue (hASH1) mRNA level as a diagnostic marker to distinguish esthesioneuroblastoma from poorly differentiated tumors arising in the sinonasal tract. Am J Clin Pathol. 2004 Jul; 122(1):100-5. View in: PubMed

Mhawech P, Greloz V, Oppikofer C, Szalay-Quinodoz I, Herrmann F. Expression of cell cycle proteins in T1a and T1b urothelial bladder carcinoma and their value in predicting tumor progression. Cancer. 2004 Jun 1; 100(11):2367-75. View in: PubMed

Billieux MH, Petignat P, Fior A, Mhawech P, Blouin JL, Dahoun S, Vassilakos P. Pre-eclampsia and peripartum cardiomyopathy in molar pregnancy: clinical implication for maternally imprinted genes. Ultrasound Obstet Gynecol. 2004 Apr; 23(4):398-401. View in: PubMed

Mhawech P, Dulguerov P, Tschanz E, Verdan C, Ares C, Allal AS. Motility-related protein-1 (MRP-1/CD9) expression can predict disease-free survival in patients with squamous cell carcinoma of the head and neck. Br J Cancer. 2004 Jan 26; 90(2):471-5. View in: PubMed

Mhawech P, Herrmann F, Coassin M, Guillou L, Iselin CE. Motility-related protein 1 (MRP-1/CD9) expression in urothelial bladder carcinoma and its relation to tumor recurrence and progression. Cancer. 2003 Oct 15; 98(8):1649-57. View in: PubMed

Terracciano LM, Glatz K, Mhawech P, Vasei M, Lehmann FS, Vecchione R, Tornillo L. Hepatoid adenocarcinoma with liver metastasis mimicking hepatocellular carcinoma: an immunohistochemical and molecular study of eight cases. Am J Surg Pathol. 2003 Oct; 27(10):1302-12. View in: PubMed

Mhawech P, Renaud A, Sene C, Lüdicke F, Herrmann F, Szalay-Quinodoz I, van den Bergh H, Major AL. High efficacy of photodynamic therapy on rat endometrium after systemic administration of benzoporphyrin derivative monoacid ring A. Hum Reprod. 2003 Aug; 18(8):1707-11. View in: PubMed

Mhawech P, Uchida T, Pelte MF. Immunohistochemical profile of high-grade urothelial bladder carcinoma and prostate adenocarcinoma. Hum Pathol. 2002 Nov; 33(11):1136-40. View in: PubMed

Mhawech P, Iselin C, Pelte MF. Value of immunohistochemistry in staging T1 urothelial bladder carcinoma. Eur Urol. 2002 Nov; 42(5):459-63. View in: PubMed

Mhawech P, Kinkel K, Vlastos G, Pelte MF. Ovarian carcinomas in endometriosis: an immunohistochemical and comparative genomic hybridization study. Int J Gynecol Pathol. 2002 Oct; 21(4):401-6. View in: PubMed

Mhawech P, Vlastos AT, Pelte MF. Pathologic quiz case. Uterine polypoid mass in a postmenopausal patient following tamoxifen treatment for breast cancer. Arch Pathol Lab Med. 2002 Sep; 126(9):1125-6. View in: PubMed

Werch JB, Mhawech P, Stager CE, Banez EI, Lichtiger B. Detecting bacteria in platelet concentrates by use of reagent strips. Transfusion. 2002 Aug; 42(8):1027-31. View in: PubMed

Mhawech P, Saleem A. Myelodysplastic syndrome: review of the cytogenetic and molecular data. Crit Rev Oncol Hematol. 2001 Dec; 40(3):229-38. View in: PubMed

Mhawech P, Dellas A, Terracciano LM. Glassy cell carcinoma of the endometrium: a case report and review of the literature. Arch Pathol Lab Med. 2001 Jun; 125(6):816-9. View in: PubMed

Mhawech P, Onorato M, Uchida T, Borucki MJ. Testicular atrophy in 80 HIV-positive patients: a multivariate statistical analysis. Int J STD AIDS. 2001 Apr; 12(4):221-4. View in: PubMed

Mhawech P, Buffone GJ, Khan SP, Gresik MV. Cytochemical staining and flow cytometry methods applied to the diagnosis of acute leukemia in the pediatric population: an assessment of relative usefulness. J Pediatr Hematol Oncol. 2001 Feb; 23(2):89-92. View in: PubMed

Terracciano LM, Patzina RA, Lehmann FS, Tornillo L, Cathomas G, Mhawech P, Vecchione R, Bianchi L. A spectrum of histopathologic findings in autoimmune liver disease. Am J Clin Pathol. 2000 Nov; 114(5):705-11. View in: PubMed

Terracciano LM, Mhawech P, Suess K, D'Armiento M, Lehmann FS, Jundt G, Moch H, Sauter G, Mihatsch MJ. Calretinin as a marker for cardiac myxoma. Diagnostic and histogenetic considerations. Am J Clin Pathol. 2000 Nov; 114(5):754-9. View in: PubMed

Mhawech P, Medeiros LJ, Bueso-Ramos C, Coffey DM, Gei AF, Shahab I. Natural killer-cell lymphoma involving the gynecologic tract. Arch Pathol Lab Med. 2000 Oct; 124(10):1510-3. View in: PubMed

Mhawech P, Saleem A. Inherited giant platelet disorders. Classification and literature review. Am J Clin Pathol. 2000 Feb; 113(2):176-90. View in: PubMed

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