Faculty

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Preet M Chaudhary, MD, PhD
Bloom Family Chair in Lymphoma Research
Chief, Nohl Division of Hematology and Center For Blood Diseases in The Department of Medicine
Director For Bone Marrow Transplant
Professor of Medicine
Medicine
NOR 3468 Health Sciences Campus Los Angeles
+1 323 865 3950

Overview

Preet M. Chaudhary, M.D., Ph.D. is chief of the Jane Anne Nohl Division of Hematology and Center for the study of Blood Diseases in the Department of Medicine, and coleader of the Molecular Genetics Program at the USC Norris Comprehensive Cancer Center. He is also Professor of Medicine, Ronald H. Bloom Family Chair in Lymphoma Research, and Program Director of the USC/Norris Blood and Marrow Transplant Program.

As a physician-scientist dedicated to hematologic oncology, Dr. Chaudhary has research interests in several areas of cancer, including AIDS-associated cancers, cancer drug resistance, biology of normal and leukemic hematopoietic stem cells, programmed cell death and cellular signaling. He is also interested in molecularly targeted and cellular therapies for leukemias, lymphomas, multiple myeloma and solid tumors. Current work in Dr. Chaudhary's laboratory is focused on developing novel strategies to improve the outcome of stem cell transplantation and the use of chimeric antigen receptor modified T cells for the treatment of cancer.

Dr. Chaudhary holds six U.S. patents and has published in some of the top scientific journals, including Cell, Immunity, JNCI, PNAS and Blood. He has served as a peer-reviewer for several national and international cancer research funding agencies and has been elected to the prestigious American Society for Clinical Investigations, an honor society of the top physician-scientists in the country.

Awards

Leukemia Lymphoma Society: Translational Research Award, 2005-2008

Leukemia Lymphoma Society: Translational Research Award, 2008-2011

Multiple Myeloma Research Foundation: Senior Research Award, 2005-2006

American Society for Clinical Investigations

Leukemia Research Foundation: New Investigator Award, 1999-2000

Howard Hughes Institutes: New Faculty Start-Up Award, 1998-2001

Damon Runyon-Walter Winchell Foundation: Postdoctoral Fellowship, 1995-1998

March of Dimes Birth Defects Foundation: Pre-doctoral Fellowship, 1990-1992

Second Prize in Ophthalmology

Gold Medal in Surgery

Second Prize in Pathology

Distinctions in Anatomy, Physiology Biochemistry and Pharmacology

Honors in First Professional M.B.B.S

Pre-Medical University Merit Certificate (First Rank in the College)

National Talent Search Scholarship

Leukemia Research Foundation: award conferred by, 1999-2000

is primary position

is primary position

March of Dimes Birth Defects Foundation: award conferred by, 1990-1992

is primary position

is primary position

Howard Hughes Institutes: award conferred by, 1998-2001

is primary position

Multiple Myeloma Research Foundation: award conferred by, 2005-2006

Damon Runyon-Walter Winchell Foundation: award conferred by, 1995-1998

Leukemia Lymphoma Society: award conferred by, 2005-2008

Leukemia Lymphoma Society: award conferred by, 2008-2011

is primary position

is primary position

ORNG Application Instance for Person

Leukemia Research Foundation: has faculty rank, 1999-2000

has faculty rank

March of Dimes Birth Defects Foundation: has faculty rank, 1990-1992

Leukemia Lymphoma Society: has faculty rank, 2005-2008

has faculty rank

Multiple Myeloma Research Foundation: has faculty rank, 2005-2006

has faculty rank

Damon Runyon-Walter Winchell Foundation: has faculty rank, 1995-1998

has faculty rank

has faculty rank

Leukemia Lymphoma Society: has faculty rank, 2008-2011

has faculty rank

Howard Hughes Institutes: has faculty rank, 1998-2001

has faculty rank

ORNG Application Instance for Person

Leukemia Research Foundation: ORNG Application Instance for Person, 1999-2000

Leukemia Lymphoma Society: ORNG Application Instance for Person, 2008-2011

Howard Hughes Institutes: ORNG Application Instance for Person, 1998-2001

ORNG Application Instance for Person

ORNG Application Instance for Person

Multiple Myeloma Research Foundation: ORNG Application Instance for Person, 2005-2006

March of Dimes Birth Defects Foundation: ORNG Application Instance for Person, 1990-1992

Leukemia Lymphoma Society: ORNG Application Instance for Person, 2005-2008

ORNG Application Instance for Person

Damon Runyon-Walter Winchell Foundation: ORNG Application Instance for Person, 1995-1998

ORNG Application Instance for Person

Howard Hughes Institutes: full name, 1998-2001

Leukemia Lymphoma Society: full name, 2005-2008

Damon Runyon-Walter Winchell Foundation: full name, 1995-1998

full name

full name

Multiple Myeloma Research Foundation: full name, 2005-2006

Leukemia Lymphoma Society: full name, 2008-2011

full name

Leukemia Research Foundation: full name, 1999-2000

full name

March of Dimes Birth Defects Foundation: full name, 1990-1992

full name

full name

full name

Leukemia Research Foundation: person in primary position, 1999-2000

person in primary position

Leukemia Lymphoma Society: person in primary position, 2005-2008

person in primary position

March of Dimes Birth Defects Foundation: person in primary position, 1990-1992

person in primary position

person in primary position

Damon Runyon-Walter Winchell Foundation: person in primary position, 1995-1998

Leukemia Lymphoma Society: person in primary position, 2008-2011

person in primary position

Howard Hughes Institutes: person in primary position, 1998-2001

Multiple Myeloma Research Foundation: person in primary position, 2005-2006

person in primary position

last name

Leukemia Lymphoma Society: last name, 2005-2008

last name

last name

Leukemia Research Foundation: last name, 1999-2000

March of Dimes Birth Defects Foundation: last name, 1990-1992

Leukemia Lymphoma Society: last name, 2008-2011

last name

Damon Runyon-Walter Winchell Foundation: last name, 1995-1998

Howard Hughes Institutes: last name, 1998-2001

last name

last name

last name

March of Dimes Birth Defects Foundation: In The News, 1990-1992

In The News

In The News

In The News

In The News

Howard Hughes Institutes: In The News, 1998-2001

Multiple Myeloma Research Foundation: In The News, 2005-2006

Damon Runyon-Walter Winchell Foundation: In The News, 1995-1998

Leukemia Research Foundation: In The News, 1999-2000

Leukemia Lymphoma Society: In The News, 2005-2008

Leukemia Lymphoma Society: In The News, 2008-2011

In The News

In The News

In The News

Leukemia Research Foundation: ORNG Application URL, 1999-2000

Leukemia Lymphoma Society: ORNG Application URL, 2008-2011

ORNG Application URL

Multiple Myeloma Research Foundation: ORNG Application URL, 2005-2006

ORNG Application URL

ORNG Application URL

Leukemia Lymphoma Society: ORNG Application URL, 2005-2008

ORNG Application URL

Damon Runyon-Walter Winchell Foundation: ORNG Application URL, 1995-1998

ORNG Application URL

ORNG Application URL

Howard Hughes Institutes: ORNG Application URL, 1998-2001

March of Dimes Birth Defects Foundation: ORNG Application URL, 1990-1992

sort order

Multiple Myeloma Research Foundation: sort order, 2005-2006

sort order

March of Dimes Birth Defects Foundation: sort order, 1990-1992

Leukemia Lymphoma Society: sort order, 2005-2008

sort order

sort order

Howard Hughes Institutes: sort order, 1998-2001

Leukemia Lymphoma Society: sort order, 2008-2011

Leukemia Research Foundation: sort order, 1999-2000

Damon Runyon-Walter Winchell Foundation: sort order, 1995-1998

sort order

sort order

sort order

March of Dimes Birth Defects Foundation: Organization, 1990-1992

Damon Runyon-Walter Winchell Foundation: Organization, 1995-1998

Leukemia Lymphoma Society: Organization, 2008-2011

Organization

Howard Hughes Institutes: Organization, 1998-2001

Organization

Multiple Myeloma Research Foundation: Organization, 2005-2006

Leukemia Lymphoma Society: Organization, 2005-2008

Organization

Organization

Organization

Organization

Organization

Howard Hughes Institutes: email address, 1998-2001

Leukemia Lymphoma Society: email address, 2005-2008

March of Dimes Birth Defects Foundation: email address, 1990-1992

email address

Multiple Myeloma Research Foundation: email address, 2005-2006

email address

email address

Damon Runyon-Walter Winchell Foundation: email address, 1995-1998

email address

email address

Leukemia Lymphoma Society: email address, 2008-2011

email address

email address

Leukemia Research Foundation: email address, 1999-2000

start date

Leukemia Lymphoma Society: start date, 2008-2011

start date

Multiple Myeloma Research Foundation: start date, 2005-2006

Damon Runyon-Walter Winchell Foundation: start date, 1995-1998

start date

start date

Leukemia Lymphoma Society: start date, 2005-2008

Leukemia Research Foundation: start date, 1999-2000

start date

March of Dimes Birth Defects Foundation: start date, 1990-1992

Howard Hughes Institutes: start date, 1998-2001

start date

start date

has ORNG Application Instance Data

has ORNG Application Instance Data

Leukemia Lymphoma Society: has ORNG Application Instance Data, 2008-2011

has ORNG Application Instance Data

has ORNG Application Instance Data

has ORNG Application Instance Data

Howard Hughes Institutes: has ORNG Application Instance Data, 1998-2001

Multiple Myeloma Research Foundation: has ORNG Application Instance Data, 2005-2006

Leukemia Lymphoma Society: has ORNG Application Instance Data, 2005-2008

March of Dimes Birth Defects Foundation: has ORNG Application Instance Data, 1990-1992

Leukemia Research Foundation: has ORNG Application Instance Data, 1999-2000

Damon Runyon-Walter Winchell Foundation: has ORNG Application Instance Data, 1995-1998

MediaLinks

March of Dimes Birth Defects Foundation: end date, 1990-1992

end date

Leukemia Research Foundation: end date, 1999-2000

Leukemia Lymphoma Society: end date, 2008-2011

Multiple Myeloma Research Foundation: end date, 2005-2006

end date

Leukemia Lymphoma Society: end date, 2005-2008

Howard Hughes Institutes: end date, 1998-2001

MediaLinks

Damon Runyon-Walter Winchell Foundation: end date, 1995-1998

MediaLinks

MediaLinks

MediaLinks

Damon Runyon-Walter Winchell Foundation: Person ID, 1995-1998

Person ID

Person ID

Leukemia Lymphoma Society: Person ID, 2008-2011

Person ID

Multiple Myeloma Research Foundation: Person ID, 2005-2006

March of Dimes Birth Defects Foundation: Person ID, 1990-1992

Leukemia Research Foundation: Person ID, 1999-2000

Person ID

Howard Hughes Institutes: Person ID, 1998-2001

Person ID

Person ID

Person ID

Damon Runyon-Walter Winchell Foundation: Keck School of Medicine of USC, 1995-1998

March of Dimes Birth Defects Foundation: Keck School of Medicine of USC, 1990-1992

Leukemia Lymphoma Society: Keck School of Medicine of USC, 2005-2008

Multiple Myeloma Research Foundation: Keck School of Medicine of USC, 2005-2006

Leukemia Research Foundation: Keck School of Medicine of USC, 1999-2000

Leukemia Lymphoma Society: Keck School of Medicine of USC, 2008-2011

Keck School of Medicine of USC

Keck School of Medicine of USC

Howard Hughes Institutes: Keck School of Medicine of USC, 1998-2001

Keck School of Medicine of USC

March of Dimes Birth Defects Foundation: workplace homepage, 1990-1992

Leukemia Lymphoma Society: workplace homepage, 2008-2011

Leukemia Research Foundation: workplace homepage, 1999-2000

workplace homepage

Damon Runyon-Walter Winchell Foundation: workplace homepage, 1995-1998

workplace homepage

Multiple Myeloma Research Foundation: workplace homepage, 2005-2006

workplace homepage

workplace homepage

Howard Hughes Institutes: workplace homepage, 1998-2001

Leukemia Lymphoma Society: workplace homepage, 2005-2008

workplace homepage

workplace homepage

workplace homepage

Keck School of Medicine of USC

Keck School of Medicine of USC

Keck School of Medicine of USC

Keck School of Medicine of USC

Professor

Leukemia Lymphoma Society: Professor, 2008-2011

Howard Hughes Institutes: Professor, 1998-2001

Professor

Professor

Leukemia Lymphoma Society: Professor, 2005-2008

Multiple Myeloma Research Foundation: Professor, 2005-2006

Professor

Professor

Professor

Damon Runyon-Walter Winchell Foundation: Professor, 1995-1998

March of Dimes Birth Defects Foundation: Professor, 1990-1992

Leukemia Research Foundation: Professor, 1999-2000

Professor

Chaudhary, Preet

Chaudhary, Preet

Chaudhary, Preet

Chaudhary, Preet

Chaudhary, Preet

Leukemia Lymphoma Society: position in organization, 2005-2008

position in organization

position in organization

Howard Hughes Institutes: position in organization, 1998-2001

Damon Runyon-Walter Winchell Foundation: position in organization, 1995-1998

Leukemia Lymphoma Society: position in organization, 2008-2011

position in organization

position in organization

Leukemia Research Foundation: position in organization, 1999-2000

Multiple Myeloma Research Foundation: position in organization, 2005-2006

position in organization

position in organization

position in organization

Chaudhary, Preet

Chaudhary, Preet

Faculty Rank

Howard Hughes Institutes: Faculty Rank, 1998-2001

Multiple Myeloma Research Foundation: Faculty Rank, 2005-2006

Faculty Rank

Faculty Rank

Leukemia Research Foundation: Faculty Rank, 1999-2000

Damon Runyon-Walter Winchell Foundation: Faculty Rank, 1995-1998

Leukemia Lymphoma Society: Faculty Rank, 2005-2008

Faculty Rank

Leukemia Lymphoma Society: Faculty Rank, 2008-2011

Faculty Rank

Faculty Rank

Faculty Rank

March of Dimes Birth Defects Foundation: Faculty Rank, 1990-1992

Multiple Myeloma Research Foundation: is primary position, 2005-2006

March of Dimes Birth Defects Foundation: is primary position, 1990-1992

Leukemia Lymphoma Society: is primary position, 2005-2008

Leukemia Lymphoma Society: is primary position, 2008-2011

Howard Hughes Institutes: is primary position, 1998-2001

Leukemia Research Foundation: is primary position, 1999-2000

Damon Runyon-Walter Winchell Foundation: is primary position, 1995-1998

links

links

links

links

links

links

person in primary position

preferred title

Leukemia Lymphoma Society: preferred title, 2008-2011

preferred title

preferred title

Multiple Myeloma Research Foundation: preferred title, 2005-2006

Leukemia Lymphoma Society: preferred title, 2005-2008

preferred title

preferred title

Leukemia Research Foundation: preferred title, 1999-2000

Howard Hughes Institutes: preferred title, 1998-2001

Damon Runyon-Walter Winchell Foundation: preferred title, 1995-1998

preferred title

preferred title

Agent

Leukemia Research Foundation: Agent, 1999-2000

Howard Hughes Institutes: Agent, 1998-2001

Leukemia Lymphoma Society: Agent, 2005-2008

Agent

Multiple Myeloma Research Foundation: Agent, 2005-2006

Agent

Leukemia Lymphoma Society: Agent, 2008-2011

Damon Runyon-Walter Winchell Foundation: Agent, 1995-1998

Agent

March of Dimes Birth Defects Foundation: Agent, 1990-1992

Agent

Agent

ORNG Application Instance for Person

has ORNG Application Instance Data

has ORNG Application Instance Data

Howard Hughes Institutes: Chaudhary, Preet, 1998-2001

Damon Runyon-Walter Winchell Foundation: Chaudhary, Preet, 1995-1998

Multiple Myeloma Research Foundation: Chaudhary, Preet, 2005-2006

Leukemia Research Foundation: Chaudhary, Preet, 1999-2000

March of Dimes Birth Defects Foundation: Chaudhary, Preet, 1990-1992

ORNG Application URL

Leukemia Research Foundation: Organization, 1999-2000

Multiple Myeloma Research Foundation: http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115, 2005-2006

Howard Hughes Institutes: http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115, 1998-2001

Leukemia Lymphoma Society: http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115, 2005-2008

http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115

http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115

Damon Runyon-Walter Winchell Foundation: http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115, 1995-1998

http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115

http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115

http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115

Leukemia Lymphoma Society: http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115, 2008-2011

Leukemia Research Foundation: http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115, 1999-2000

March of Dimes Birth Defects Foundation: http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115, 1990-1992

http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115

http://orng.info/ontology/orng#ApplicationInstance^^ORNG Application Instance^^850-115

ORNG Application Instance Data value

ORNG Application Instance Data value

ORNG Application Instance Data value

Damon Runyon-Walter Winchell Foundation: ORNG Application Instance Data value, 1995-1998

March of Dimes Birth Defects Foundation: ORNG Application Instance Data value, 1990-1992

ORNG Application Instance Data value

ORNG Application Instance Data value

Howard Hughes Institutes: ORNG Application Instance Data value, 1998-2001

Multiple Myeloma Research Foundation: ORNG Application Instance Data value, 2005-2006

Leukemia Lymphoma Society: ORNG Application Instance Data value, 2008-2011

ORNG Application Instance Data value

Leukemia Research Foundation: ORNG Application Instance Data value, 1999-2000

ORNG Application Instance Data value

Medicine

Medicine

Medicine

Medicine

Leukemia Lymphoma Society: ORNG Application Instance Data value, 2005-2008

Leukemia Lymphoma Society: MediaLinks, 2008-2011

Leukemia Research Foundation: MediaLinks, 1999-2000

Leukemia Lymphoma Society: MediaLinks, 2005-2008

Howard Hughes Institutes: MediaLinks, 1998-2001

MediaLinks

Multiple Myeloma Research Foundation: MediaLinks, 2005-2006

MediaLinks

March of Dimes Birth Defects Foundation: MediaLinks, 1990-1992

Damon Runyon-Walter Winchell Foundation: MediaLinks, 1995-1998

March of Dimes Birth Defects Foundation: Position, 1990-1992

Leukemia Lymphoma Society: Position, 2008-2011

Position

Position

Position

Multiple Myeloma Research Foundation: Position, 2005-2006

Leukemia Research Foundation: Position, 1999-2000

Position

Damon Runyon-Walter Winchell Foundation: Position, 1995-1998

Leukemia Lymphoma Society: Position, 2005-2008

Position

Howard Hughes Institutes: Position, 1998-2001

Position

Position

March of Dimes Birth Defects Foundation: position in organization, 1990-1992

March of Dimes Birth Defects Foundation: HR job title, 1990-1992

Multiple Myeloma Research Foundation: HR job title, 2005-2006

Damon Runyon-Walter Winchell Foundation: HR job title, 1995-1998

Leukemia Lymphoma Society: HR job title, 2005-2008

HR job title

Howard Hughes Institutes: HR job title, 1998-2001

Leukemia Lymphoma Society: HR job title, 2008-2011

HR job title

HR job title

Leukemia Research Foundation: HR job title, 1999-2000

HR job title

HR job title

HR job title

first name

first name

first name

first name

first name

ORNG Application Instance of Application

ORNG Application Instance of Application

ORNG Application Instance of Application

Leukemia Lymphoma Society: ORNG Application Instance of Application, 2008-2011

Leukemia Research Foundation: ORNG Application Instance of Application, 1999-2000

Multiple Myeloma Research Foundation: ORNG Application Instance of Application, 2005-2006

Howard Hughes Institutes: ORNG Application Instance of Application, 1998-2001

ORNG Application Instance of Application

March of Dimes Birth Defects Foundation: ORNG Application Instance of Application, 1990-1992

Leukemia Lymphoma Society: ORNG Application Instance of Application, 2005-2008

Damon Runyon-Walter Winchell Foundation: ORNG Application Instance of Application, 1995-1998

ORNG Application Instance of Application

ORNG Application Instance of Application

ORNG Application Instance of Application

Howard Hughes Institutes: Medicine, 1998-2001

March of Dimes Birth Defects Foundation: Medicine, 1990-1992

Leukemia Lymphoma Society: Medicine, 2005-2008

Multiple Myeloma Research Foundation: Medicine, 2005-2006

Medicine

Damon Runyon-Walter Winchell Foundation: Medicine, 1995-1998

Leukemia Lymphoma Society: Medicine, 2008-2011

Leukemia Research Foundation: Medicine, 1999-2000

Medicine

Medicine

Multiple Myeloma Research Foundation: label, 2005-2006

Leukemia Research Foundation: label, 1999-2000

Damon Runyon-Walter Winchell Foundation: label, 1995-1998

label

Leukemia Lymphoma Society: label, 2005-2008

label

label

Howard Hughes Institutes: label, 1998-2001

label

Leukemia Lymphoma Society: label, 2008-2011

label

March of Dimes Birth Defects Foundation: label, 1990-1992

label

label

Publications

DiseaseConnect: a comprehensive web server for mechanism-based disease-disease connections. Nucleic Acids Res. 2014 Jul; 42(Web Server issue):W137-46. View in: PubMed

NEMO Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Encoded vFLIP K13-Induced Gene Expression and Protection against Death Receptor-Induced Cell Death, and Its N-Terminal 251 Residues Are Sufficient for This Process. J Virol. 2014 Jun; 88(11):6345-54. View in: PubMed

A purine scaffold HSP90 inhibitor BIIB021 has selective activity against KSHV-associated primary effusion lymphoma and blocks vFLIP K13-induced NF-?B. A purine scaffold HSP90 inhibitor BIIB021 has selective activity against KSHV-associated primary effusion lymphoma and blocks vFLIP K13-induced NF-? B. Clin Cancer Res. 2013 Sep 15; 19(18):5016-26. View in: PubMed

Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor-induced growth arrest and apoptosis through NF-?B activation. Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor-induced growth arrest and apoptosis through NF-? B activation. J Virol. 2013 Feb; 87(4):2242-52. View in: PubMed

A Computational Profiling of Changes in Gene Expression and Transcription Factors Induced by vFLIP K13 in Primary Effusion Lymphoma. PLoS One. 2012; 7(5):e37498. View in: PubMed

Kaposi's Sarcoma Associated Herpesvirus Encoded Viral FLICE Inhibitory Protein K13 Activates NF-?B Pathway Independent of TRAF6, TAK1 and LUBAC. PLoS One. 2012; 7(5):e36601. View in: PubMed

Constitutive NF-kappaB activation confers interleukin 6 (IL6) independence and resistance to dexamethasone and Janus kinase inhibitor INCB018424 in murine plasmacytoma cells. J Biol Chem. 2011 Aug 12; 286(32):27988-97. View in: PubMed

A20 is induced by Kaposi sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 and blocks K13-induced nuclear factor-kappaB in a negative feedback manner. J Biol Chem. 2011 Jun 17; 286(24):21555-64. View in: PubMed

Kaposi sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 cooperates with Myc to promote lymphoma in mice. Cancer Biol Ther. 2010 Nov; 10(10):1033-40. View in: PubMed

Immune evasion by Kaposi's sarcoma-associated herpesvirus. Future Microbiol. 2010 Sep; 5(9):1349-65. View in: PubMed

Induction, regulation, and biologic function of Axl receptor tyrosine kinase in Kaposi sarcoma. Blood. 2010 Jul 15; 116(2):297-305. View in: PubMed

Lack of evidence for direct involvement of Merkel cell polyomavirus (MCV) in chronic lymphocytic leukemia (CLL). Blood. 2010 Jun 10; 115(23):4973-4. View in: PubMed

X-linked ectodermal dysplasia receptor is downregulated in breast cancer via promoter methylation. Clin Cancer Res. 2010 Feb 15; 16(4):1140-8. View in: PubMed

KSHV-induced notch components render endothelial and mural cell characteristics and cell survival. Blood. 2010 Jan 28; 115(4):887-95. View in: PubMed

Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors. Int J Cancer. 2009 Sep 15; 125(6):1243-9. View in: PubMed

Induction of CCL20 production by Kaposi sarcoma-associated herpesvirus: role of viral FLICE inhibitory protein K13-induced NF-kappaB activation. Blood. 2009 May 28; 113(22):5660-8. View in: PubMed

Integrated microarray and multiplex cytokine analyses of Kaposi's Sarcoma Associated Herpesvirus viral FLICE Inhibitory Protein K13 affected genes and cytokines in human blood vascular endothelial cells. BMC Med Genomics. 2009; 2:50. View in: PubMed

Resolving "kinks" of chemotherapy in melanoma. J Natl Cancer Inst. 2008 Jun 18; 100(12):833-5. View in: PubMed

Proteasome inhibitor Bortezomib induces cell cycle arrest and apoptosis in cell lines derived from Ewing's sarcoma family of tumors and synergizes with TRAIL. Cancer Biol Ther. 2008 Apr; 7(4):603-8. View in: PubMed

Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation. J Biol Chem. 2007 Aug 24; 282(34):24858-65. View in: PubMed

In primary effusion lymphoma cells, MYB transcriptional repression is associated with v-FLIP expression during latent KSHV infection while both v-FLIP and v-GPCR become involved during the lytic cycle. Br J Haematol. 2007 Aug; 138(4):487-501. View in: PubMed

Constitutive NF-kappaB activation, normal Fas-induced apoptosis, and increased incidence of lymphoma in human herpes virus 8 K13 transgenic mice. Proc Natl Acad Sci U S A. 2005 Sep 6; 102(36):12885-90. View in: PubMed

The proteasome inhibitor bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells. Cancer Biol Ther. 2005 Jan; 4(1):77-82. View in: PubMed

Kaposi's sarcoma associated herpes virus-encoded viral FLICE inhibitory protein activates transcription from HIV-1 Long Terminal Repeat via the classical NF-kappaB pathway and functionally cooperates with Tat. Retrovirology. 2005; 2:9. View in: PubMed

An evolutionary conserved pathway of nuclear factor-kappaB activation involving caspase-mediated cleavage and N-end rule pathway-mediated degradation of IkappaBalpha. J Biol Chem. 2004 Sep 17; 279(38):39358-65. View in: PubMed

Activation of alternative NF-kappa B pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 beta-converting enzyme inhibitory protein (vFLIP). Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9399-404. View in: PubMed

Aberrant methylation of trail decoy receptor genes is frequent in multiple tumor types. Int J Cancer. 2004 May 1; 109(5):786-92. View in: PubMed

The ectodermal dysplasia receptor represses the Lef-1/beta-catenin-dependent transcription independent of NF-kappaB activation. Biochem Biophys Res Commun. 2004 Feb 27; 315(1):73-8. View in: PubMed

The human herpes virus 8-encoded viral FLICE-inhibitory protein induces cellular transformation via NF-kappaB activation. J Biol Chem. 2003 Dec 26; 278(52):52437-45. View in: PubMed

Molecular genetic analysis of human herpes virus 8-encoded viral FLICE inhibitory protein-induced NF-kappaB activation. J Biol Chem. 2003 Dec 26; 278(52):52406-11. View in: PubMed

Use of adeno-associated viral vector for delivery of small interfering RNA. Oncogene. 2003 Aug 28; 22(36):5712-5. View in: PubMed

Eiger and its receptor, Wengen, comprise a TNF-like system in Drosophila. Oncogene. 2003 Jul 31; 22(31):4860-7. View in: PubMed

The human herpes virus 8-encoded viral FLICE inhibitory protein protects against growth factor withdrawal-induced apoptosis via NF-kappa B activation. Blood. 2003 Mar 1; 101(5):1956-61. View in: PubMed

Use of lentiviral vectors for delivery of small interfering RNA. Cancer Biol Ther. 2003 Mar-Apr; 2(2):206-10. View in: PubMed

Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification. Oncogene. 2002 Dec 5; 21(55):8510-4. View in: PubMed

Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked ectodermal dysplasia receptor. J Biol Chem. 2002 Nov 22; 277(47):44953-61. View in: PubMed

Role of MRIT/cFLIP in protection against chemotherapy-induced apoptosis. Cancer Biol Ther. 2002 Nov-Dec; 1(6):652-60. View in: PubMed

Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines. Cancer Res. 2002 Oct 15; 62(20):5897-901. View in: PubMed

The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the Ikappa B kinase complex. J Biol Chem. 2002 Apr 19; 277(16):13745-51. View in: PubMed

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