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Ray Matthews, MD
Professor of Clinical Medicine
Chief, Division of Cardiovascular Medicine, Department of Medicine
Director of Interventional Cardiology and Catheterization Laboratories
HCC 322 Health Sciences Campus Los Angeles
+1 323 442 6130


Dr. Matthews was recruited to the University of Southern California faculty in 2007 to direct the Department of Interventional Cardiology. He brings 20 years of experience in high-level tertiary interventional cardiology to the institution. Dr. Matthews has emerged as a leader in the advancement of percutaneous treatment of peripheral vascular disease.

He remains very active in the clinical investigation and use of new devices and techniques for the treatment of coronary artery disease and carotid artery disease. In addition, Dr. Matthews was among the first in Los Angeles to percutaneously close structural cardiac defects, such as atrial septal defect and to patent foreman ovale. Dr. Matthews previously served as head of an interventional cardiology training program that trained over 50 interventional cardiologists, many have gone on to successful careers all over the world.


American Heart Association: Group Investigator Award, 1986

Harbor-UCLA Medical Center: Distinguished Teaching Award, 1987

American Heart Association : First Place, Clinical Division, Laverne Titus Young Investigator Competition, 1987

Division of Cardiovascular Medicine, Keck School of Medicine of USC: Golden Apple Award for Outstanding Teaching, 2013


Shavelle DM, Kirtane AJ, Schreiber TL, Kapasi NK, O'Neill WW, Moses JW, Popma J, Matthews RV. Impact of Surgical Consultation on Outcomes in Hemodynamically Supported High-Risk Percutaneous Coronary Intervention: Insights From PROTECT II Randomized Study. J Invasive Cardiol. 2016 May; 28(5):187-92. View in: PubMed

Clavijo LC, Cortes GA, Jolly A, Tun H, Mehra A, Gaglia MA, Shavelle D, Matthews RV. Same-day discharge after coronary stenting and femoral artery device closure: A randomized study in stable and low-risk acute coronary syndrome patients. Cardiovasc Revasc Med. 2016 Apr-May; 17(3):155-61. View in: PubMed

Christianson L, Matthews RV, Rahimtoola SH. The Reply. Am J Med. 2015 Sep; 128(9):e35. View in: PubMed

Christianson L, Matthews RV, Rahmitoola SH. Early Repolarization Masquerading as STEMI. Am J Med. 2014 Nov; 127(11):e1-2. View in: PubMed

Pahlevan NM, Tavallali P, Rinderknecht DG, Petrasek D, Matthews RV, Hou TY, Gharib M. Intrinsic frequency for a systems approach to haemodynamic waveform analysis with clinical applications. J R Soc Interface. 2014 Sep 6; 11(98). View in: PubMed

Hui DS, Shavelle DM, Cunningham MJ, Matthews RV, Starnes VA. Contemporary use of balloon aortic valvuloplasty in the era of transcatheter aortic valve implantation. Tex Heart Inst J. 2014 Sep; 41(5):469-76. View in: PubMed

Gaglia MA, Shavelle DM, Tun H, Bhatt J, Mehra A, Matthews RV, Clavijo L. African-American patients are less likely to receive drug-eluting stents during percutaneous coronary intervention. Cardiovasc Revasc Med. 2014 Jun; 15(4):214-8. View in: PubMed

Shavelle DM, Chen AY, Matthews RV, Roe MT, de Lemos JA, Jollis J, Thomas JL, French WJ. Predictors of Reperfusion Delay in Patients With ST Elevation Myocardial Infarction Self-Transported to the Hospital (from the American Heart Association's Mission: Lifeline Program). Am J Cardiol. 2014 Mar 1; 113(5):798-802. View in: PubMed

Prasad A, Zareh M, Doherty R, Gopal A, Vora H, Somma K, Mehra A, Clavijo LC, Matthews RV, Shavelle DM. Use of regadenoson for measurement of fractional flow reserve. Catheter Cardiovasc Interv. 2014 Feb 15; 83(3):369-74. View in: PubMed

Shavelle DM, Zheng L, Ottochian M, Wagman B, Testa N, Hall S, Koenig W, Chan LS, Matthews RV. Time of day variation in door-to-balloon time for STEMI patients in Los Angeles County: does time of day make a difference? Acute Card Care. 2013 Sep; 15(3):52-7. View in: PubMed

Matthews RV. Catheter intervention in structural heart disease. Preface. Cardiol Clin. 2013 Aug; 31(3):ix-x. View in: PubMed

Matthews RV, Shavelle DM. Transcatheter aortic valve replacement with CoreValve. Cardiol Clin. 2013 Aug; 31(3):351-61. View in: PubMed

Shinbane JS, Shriki J, Fleischman F, Hindoyan A, Withey J, Lee C, Wilcox A, Cunningham M, Baker C, Matthews RV, Starnes V. Anomalous coronary arteries: cardiovascular computed tomographic angiography for surgical decisions and planning. World J Pediatr Congenit Heart Surg. 2013 Apr; 4(2):142-54. View in: PubMed

Al-Ameri H, Clavijo L, Matthews RV, Kloner RA, Shavelle DM. Devices to treat peripheral chronic total occlusions. J Interv Cardiol. 2012 Aug; 25(4):395-403. View in: PubMed

Shah R, Thomson A, Atianzar K, Somma K, Mehra A, Clavijo L, Matthews RV, Shavelle DM. Percutaneous left ventricular support for high-risk PCI and cardiogenic shock: who gets what? Cardiovasc Revasc Med. 2012 Mar; 13(2):101-5. View in: PubMed

Shavelle DM, Clavijo L, Matthews RV. Percutaneous devices to support the left ventricle. Expert Rev Med Devices. 2011 Nov; 8(6):681-94. View in: PubMed

Visrodia K, Matthews R, Shriki J. Double-stent method: an alternative technique to treat coronary artery aneurysms. Catheter Cardiovasc Interv. 2011 Jun 1; 77(7):1036-41. View in: PubMed

Chen SF, El-Bialy A, Matthews R, Clavijo L. Use of drug-eluting versus bare-metal stents in ST-segment elevation myocardial infarction. J Invasive Cardiol. 2009 Nov; 21(11):E206-12. View in: PubMed

Al-Ameri H, Shin V, Mayeda GS, Burstein S, Matthews RV, Kloner RA, Shavelle DM. Peripheral chronic total occlusions treated with subintimal angioplasty and a true lumen re-entry device. J Invasive Cardiol. 2009 Sep; 21(9):468-72. View in: PubMed

Momplaisir T, Matthews RV. Paravalvular mitral regurgitation treated with an amplatzer septal occluder device: a case report and review of the literature. J Invasive Cardiol. 2007 Feb; 19(2):E46-50. View in: PubMed

Shareghi S, Rasouli L, Shavelle DM, Burstein S, Matthews RV. Current results of balloon aortic valvuloplasty in high-risk patients. J Invasive Cardiol. 2007 Jan; 19(1):1-5. View in: PubMed

Sherev DA, Shavelle DM, Abdelkarim M, Shook T, Mayeda GS, Burstein S, Matthews RV. AngioJet Rheolytic thrombectomy during rescue PCI for failed thrombolysis: a single-center experience. J Invasive Cardiol. 2006 Jul; 18 Suppl C:12C-16C. View in: PubMed

Shavelle DM, Salami A, Abdelkarim M, French WJ, Shook TL, Mayeda GS, Burstein S, Matthews RV. Rescue percutaneous coronary intervention for failed thrombolysis. Catheter Cardiovasc Interv. 2006 Feb; 67(2):214-20. View in: PubMed

AboulHosn J, French WJ, Buljubasic N, Matthews RV, Budoff MJ, Shavelle DM. Electron beam angiography for the evaluation of percutaneous atrial septal defect closure. Catheter Cardiovasc Interv. 2005 Aug; 65(4):565-8. View in: PubMed

Ostermayer SH, Reisman M, Kramer PH, Matthews RV, Gray WA, Block PC, Omran H, Bartorelli AL, Della Bella P, Di Mario C, Pappone C, Casale PN, Moses JW, Poppas A, Williams DO, Meier B, Skanes A, Teirstein PS, Lesh MD, Nakai T, Bayard Y, Billinger K, Trepels T, Krumsdorf U, Sievert H. Percutaneous left atrial appendage transcatheter occlusion (PLAATO system) to prevent stroke in high-risk patients with non-rheumatic atrial fibrillation: results from the international multi-center feasibility trials. J Am Coll Cardiol. 2005 Jul 5; 46(1):9-14. View in: PubMed

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