Faculty

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Rex A. Moats, PhD
Associate Professor of Research Pathology and Radiology
Scientific Director of Small Animal Research
Pediatrics
CHL Mail Stop 81 Off Campus Los Angeles
+1 323 361 8503

Publications

Structural and Functional Characterization of Human Stem-Cell-Derived Retinal Organoids by Live Imaging. Invest Ophthalmol Vis Sci. 2017 Jul 01; 58(9):3311-3318. View in: PubMed

Intestinal adaptation in proximal and distal segments: Two epithelial responses diverge after intestinal separation. Surgery. 2017 Apr; 161(4):1016-1027. View in: PubMed

Optimization of a Neural Stem-Cell-Mediated Carboxylesterase/Irinotecan Gene Therapy for Metastatic Neuroblastoma. Mol Ther Oncolytics. 2017 Mar 17; 4:67-76. View in: PubMed

Intestinal adaptation in proximal and distal segments: Two epithelial responses diverge after intestinal separation. Surgery. 2016 Dec 20. View in: PubMed

An allograft mouse model for the study of hearing loss secondary to vestibular schwannoma growth. J Neurooncol. 2016 Aug; 129(1):47-56. View in: PubMed

BarTeL, a Genetically Versatile, Bioluminescent and Granule Neuron Precursor-Targeted Mouse Model for Medulloblastoma. PLoS One. 2016; 11(6):e0156907. View in: PubMed

A corrole nanobiologic elicits tissue-activated MRI contrast enhancement and tumor-targeted toxicity. J Control Release. 2015 Nov 10; 217:92-101. View in: PubMed

Increased alveolar soluble annexin V promotes lung inflammation and fibrosis. Eur Respir J. 2015 Nov; 46(5):1417-29. View in: PubMed

Adult zebrafish intestine resection: a novel model of short bowel syndrome, adaptation, and intestinal stem cell regeneration. Am J Physiol Gastrointest Liver Physiol. 2015 Aug 01; 309(3):G135-45. View in: PubMed

Adult zebrafish intestine resection: a novel model of short bowel syndrome, adaptation, and intestinal stem cell regeneration. Am J Physiol Gastrointest Liver Physiol. 2015 Aug 1; 309(3):G135-45. View in: PubMed

Dynamic imaging of the growth plate cartilage reveals multiple contributors to skeletal morphogenesis. Nat Commun. 2015 Apr 13; 6:6798. View in: PubMed

Juvenile skeletogenesis in anciently diverged sea urchin clades. Dev Biol. 2015 Apr 01; 400(1):148-58. View in: PubMed

Juvenile skeletogenesis in anciently diverged sea urchin clades. Dev Biol. 2015 Apr 1; 400(1):148-58. View in: PubMed

Analysis of glioblastoma tumor coverage by oncolytic virus-loaded neural stem cells using MRI-based tracking and histological reconstruction. Cancer Gene Ther. 2015 Jan; 22(1):55-61. View in: PubMed

Dynamic imaging of the growth plate cartilage reveals multiple contributors to skeletal morphogenesis. Nat Commun. 2015; 6:6798. View in: PubMed

Cellular uptake and cytotoxicity of a near-IR fluorescent corrole-TiO2 nanoconjugate. J Inorg Biochem. 2014 Nov; 140:39-44. View in: PubMed

Integrin a2ß1 targeted GdVO4:Eu ultrathin nanosheet for multimodal PET/MR imaging. Biomaterials. 2014 Oct; 35(30):8649-58. View in: PubMed

Magnetic resonance imaging tracking of ferumoxytol-labeled human neural stem cells: studies leading to clinical use. Stem Cells Transl Med. 2013 Oct; 2(10):766-75. View in: PubMed

Functionalized magnetonanoparticles in visualization of intracranial tumors on MRI. Mol Imaging Biol. 2013 Jun; 15(3):299-306. View in: PubMed

Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies. Sci Transl Med. 2013 May 8; 5(184):184ra59. View in: PubMed

Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies. Sci Transl Med. 2013 May 08; 5(184):184ra59. View in: PubMed

Decorating metal oxide surfaces with fluorescent chlorosulfonated corroles. Inorg Chem. 2013 May 06; 52(9):4774-6. View in: PubMed

Decorating metal oxide surfaces with fluorescent chlorosulfonated corroles. Inorg Chem. 2013 May 6; 52(9):4774-6. View in: PubMed

Neural stem cell-mediated CE/CPT-11 enzyme/prodrug therapy in transgenic mouse model of intracerebellar medulloblastoma. Gene Ther. 2013 Feb; 20(2):143-50. View in: PubMed

Imaging brain neuronal activity using functionalized magnetonanoparticles and MRI. Brain Topogr. 2012 Oct; 25(4):374-88. View in: PubMed

Novel cell lines established from pediatric brain tumors. J Neurooncol. 2012 Apr; 107(2):269-80. View in: PubMed

Automatic abdominal fat assessment in obese mice using a segmental shape model. J Magn Reson Imaging. 2011 Oct; 34(4):866-73. View in: PubMed

Adipose segmentation in small animals at 7T: a preliminary study. BMC Genomics. 2010 Dec 01; 11 Suppl 3:S9. View in: PubMed

Adipose segmentation in small animals at 7T: a preliminary study. BMC Genomics. 2010; 11 Suppl 3:S9. View in: PubMed

Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model. PLoS One. 2009 Sep 29; 4(9):e7218. View in: PubMed

S-adenosylmethionine in the chemoprevention and treatment of hepatocellular carcinoma in a rat model. Hepatology. 2009 Aug; 50(2):462-71. View in: PubMed

Shape-aided kidney extraction in MR urography. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:5781-4. View in: PubMed

Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model. PLoS One. 2009; 4(9):e7218. View in: PubMed

Biglycan overexpression on tooth enamel formation in transgenic mice. Anat Rec (Hoboken). 2008 Oct; 291(10):1246-53. View in: PubMed

Corticotomy-/osteotomy-assisted tooth movement microCTs differ. J Dent Res. 2008 Sep; 87(9):861-7. View in: PubMed

Functionalized magnetonanoparticles for MRI diagnosis and localization in epilepsy. Epilepsia. 2008 Aug; 49(8):1419-30. View in: PubMed

Influence of iron chelation on R1 and R2 calibration curves in gerbil liver and heart. Magn Reson Med. 2008 Jul; 60(1):82-9. View in: PubMed

The activity of zoledronic Acid on neuroblastoma bone metastasis involves inhibition of osteoclasts and tumor cell survival and proliferation. Cancer Res. 2007 Oct 1; 67(19):9346-55. View in: PubMed

The activity of zoledronic Acid on neuroblastoma bone metastasis involves inhibition of osteoclasts and tumor cell survival and proliferation. Cancer Res. 2007 Oct 01; 67(19):9346-55. View in: PubMed

Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence. Cancer Res. 2007 Aug 1; 67(15):7525-33. View in: PubMed

Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence. Cancer Res. 2007 Aug 01; 67(15):7525-33. View in: PubMed

Comparison of twice-daily vs once-daily deferasirox dosing in a gerbil model of iron cardiomyopathy. Exp Hematol. 2007 Jul; 35(7):1069-73. View in: PubMed

Antioxidant-mediated effects in a gerbil model of iron overload. Acta Haematol. 2007; 118(4):193-9. View in: PubMed

Deferasirox and deferiprone remove cardiac iron in the iron-overloaded gerbil. Transl Res. 2006 Nov; 148(5):272-80. View in: PubMed

Smad3 deficiency promotes tumorigenesis in the distal colon of ApcMin/+ mice. Cancer Res. 2006 Sep 01; 66(17):8430-8. View in: PubMed

Smad3 deficiency promotes tumorigenesis in the distal colon of ApcMin/+ mice. Cancer Res. 2006 Sep 1; 66(17):8430-8. View in: PubMed

Multimodal imaging analysis of tumor progression and bone resorption in a murine cancer model. J Comput Assist Tomogr. 2006 May-Jun; 30(3):525-34. View in: PubMed

Longitudinal microPET imaging of brain tumor growth with F-18-labeled RGD peptide. Mol Imaging Biol. 2006 Jan-Feb; 8(1):9-15. View in: PubMed

Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging. Phys Med Biol. 2005 Dec 07; 50(23):5421-41. View in: PubMed

Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging. Phys Med Biol. 2005 Dec 7; 50(23):5421-41. View in: PubMed

Inter-individual variation in brain phenylalanine concentration in patients with PKU is not caused by genetic variation in the 4F2hc/LAT1 complex. Mol Genet Metab. 2005 Dec; 86 Suppl 1:S119-23. View in: PubMed

Cardiac iron determines cardiac T2*, T2, and T1 in the gerbil model of iron cardiomyopathy. Circulation. 2005 Jul 26; 112(4):535-43. View in: PubMed

Neonatal gene therapy of MPS I mice by intravenous injection of a lentiviral vector. Mol Ther. 2005 May; 11(5):776-89. View in: PubMed

Physiology and pathophysiology of iron cardiomyopathy in thalassemia. Ann N Y Acad Sci. 2005; 1054:386-95. View in: PubMed

Assessing growth and response to therapy in murine tumor models. Methods Mol Med. 2005; 111:335-50. View in: PubMed

In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts. Cancer Res. 2004 Nov 1; 64(21):8009-14. View in: PubMed

In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in brain tumor xenografts. Cancer Res. 2004 Nov 01; 64(21):8009-14. View in: PubMed

18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis. Nucl Med Biol. 2004 Feb; 31(2):179-89. View in: PubMed

Neuropsychological outcome of subjects participating in the PKU adult collaborative study: a preliminary review. J Inherit Metab Dis. 2004; 27(5):549-66. View in: PubMed

Brain phenylalanine concentrations in phenylketonuria: research and treatment of adults. Pediatrics. 2003 Dec; 112(6 Pt 2):1575-9. View in: PubMed

Micro-MRI at 11. 7 T of a murine brain tumor model using delayed contrast enhancement. Mol Imaging. 2003 Jul; 2(3):150-8. View in: PubMed

Large neutral amino acid therapy and phenylketonuria: a promising approach to treatment. Mol Genet Metab. 2003 Jun; 79(2):110-3. View in: PubMed

Time course of bioluminescent signal in orthotopic and heterotopic brain tumors in nude mice. Biotechniques. 2003 Jun; 34(6):1184-8. View in: PubMed

Danger of high-protein dietary supplements to persons with hyperphenylalaninaemia. J Inherit Metab Dis. 2003; 26(4):339-42. View in: PubMed

Craniosynostosis in transgenic mice overexpressing Nell-1. J Clin Invest. 2002 Sep; 110(6):861-70. View in: PubMed

Blood-brain phenylalanine relationships in persons with phenylketonuria. Pediatrics. 2000 Nov; 106(5):1093-6. View in: PubMed

High resolution magnetic resonance imaging of the brain in the dy/dy mouse with merosin-deficient congenital muscular dystrophy. Neuromuscul Disord. 2000 Jun; 10(4-5):292-8. View in: PubMed

In vivo visualization of gene expression using magnetic resonance imaging. Nat Biotechnol. 2000 Mar; 18(3):321-5. View in: PubMed

Brain phenylalanine concentration in the management of adults with phenylketonuria. J Inherit Metab Dis. 2000 Feb; 23(1):7-14. View in: PubMed

Magnetic resonance imaging for the evaluation of a novel metastatic orthotopic model of human neuroblastoma in immunodeficient mice. Clin Exp Metastasis. 2000; 18(6):455-61. View in: PubMed

Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases. Neurology. 1998 Apr; 50(4):1033-40. View in: PubMed

Evaluation of automated MR spectroscopy: application in Alzheimer disease. AJNR Am J Neuroradiol. 1995 Oct; 16(9):1779-82. View in: PubMed

Added value of automated clinical proton MR spectroscopy of the brain. J Comput Assist Tomogr. 1995 May-Jun; 19(3):480-91. View in: PubMed

Probable Alzheimer disease: diagnosis with proton MR spectroscopy. Radiology. 1995 Apr; 195(1):65-72. View in: PubMed

Subclinical hepatic encephalopathy: proton MR spectroscopic abnormalities. Radiology. 1994 Nov; 193(2):457-63. View in: PubMed

Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease. Magn Reson Med. 1994 Jul; 32(1):110-5. View in: PubMed

Automated single-voxel proton MRS: technical development and multisite verification. Magn Reson Med. 1994 Apr; 31(4):365-73. View in: PubMed

Decrease in cerebral inositols in rats and humans. Biochem J. 1993 Oct 1; 295 ( Pt 1):15-8. View in: PubMed

Decrease in cerebral inositols in rats and humans. Biochem J. 1993 Oct 01; 295 ( Pt 1):15-8. View in: PubMed

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