Faculty

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Rob Scot McConnell, MD
Professor of Preventive Medicine
Environmental Health
SSB 230D 2001 N. Soto Street Health Sciences Campus Los Angeles
+1 323 442 1593

Overview

Rob S. McConnell is Professor of Preventive Medicine and Deputy Director of the NIEHS/EPA-supported Children's Environmental Health Center. His research interests include effects of air pollution on the development and exacerbation of asthma, and he is the principal investigator of a large prospective cohort study in the Children's USC Health Study to investigate these relationships. His work examining the associations between ozone and fresh traffic emissions with the development of asthma has contributed to the current policy debate on proper regulation of these exposures. Dr. McConnell is also interested in the effects of psychosocial stress and other social characteristics on asthma and on the application of new biomarkers of exposure to air pollutants in population based studies. He teaches the survey course on environmental health in the USC Masters of Public Health program.

Awards

Stanford University: Chemistry Honors Program, 1971

Stanford University: Phi Beta Kappa, 1976

Diplomate American Board of Internal Medicine: Specialty Certification, 1983

Publications

Barrington-Trimis JL, Urman R, Leventhal AM, Gauderman WJ, Cruz TB, Gilreath TD, Howland S, Unger JB, Berhane K, Samet JM, McConnell R. E-cigarettes, Cigarettes, and the Prevalence of Adolescent Tobacco Use. Pediatrics. 2016 Aug; 138(2). View in: PubMed

Younan D, Tuvblad C, Li L, Wu J, Lurmann F, Franklin M, Berhane K, McConnell R, Wu AH, Baker LA, Chen JC. Environmental Determinants of Aggression in Adolescents: Role of Urban Neighborhood Greenspace. J Am Acad Child Adolesc Psychiatry. 2016 Jul; 55(7):591-601. View in: PubMed

Barrington-Trimis JL, Urman R, Berhane K, Unger JB, Cruz TB, Pentz MA, Samet JM, Leventhal AM, McConnell R. E-Cigarettes and Future Cigarette Use. Pediatrics. 2016 Jul; 138(1). View in: PubMed

Barrington-Trimis JL, Berhane K, Unger JB, Cruz TB, Urman R, Chou CP, Howland S, Wang K, Pentz MA, Gilreath TD, Huh J, Leventhal AM, Samet JM, McConnell R. The E-cigarette Social Environment, E-cigarette Use, and Susceptibility to Cigarette Smoking. J Adolesc Health. 2016 Jul; 59(1):75-80. View in: PubMed

Berhane K, Chang CC, McConnell R, Gauderman WJ, Avol E, Rapapport E, Urman R, Lurmann F, Gilliland F. Association of Changes in Air Quality With Bronchitic Symptoms in Children in California, 1993-2012. JAMA. 2016 Apr 12; 315(14):1491-501. View in: PubMed

Gilreath TD, Leventhal A, Barrington-Trimis JL, Unger JB, Cruz TB, Berhane K, Huh J, Urman R, Wang K, Howland S, Pentz MA, Chou CP, McConnell R. Patterns of Alternative Tobacco Product Use: Emergence of Hookah and E-cigarettes as Preferred Products Amongst Youth. J Adolesc Health. 2016 Feb; 58(2):181-5. View in: PubMed

Ghosh R, Lurmann F, Perez L, Penfold B, Brandt S, Wilson J, Milet M, Künzli N, McConnell R. Near-Roadway Air Pollution and Coronary Heart Disease: Burden of Disease and Potential Impact of a Greenhouse Gas Reduction Strategy in Southern California. Environ Health Perspect. 2016 Feb; 124(2):193-200. View in: PubMed

Dunton G, Dzubur E, Li M, Huh J, Intille S, McConnell R. Momentary Assessment of Psychosocial Stressors, Context, and Asthma Symptoms in Hispanic Adolescents. Behav Modif. 2016 Jan; 40(1-2):257-80. View in: PubMed

Breton CV, Mack WJ, Yao J, Berhane K, Amadeus M, Lurmann F, Gilliland F, McConnell R, Hodis HN, Künzli N, Avol E. Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults. PLoS One. 2016; 11(3):e0150825. View in: PubMed

Barrington-Trimis JL, Berhane K, Unger JB, Cruz TB, Huh J, Leventhal AM, Urman R, Wang K, Howland S, Gilreath TD, Chou CP, Pentz MA, McConnell R. Psychosocial Factors Associated With Adolescent Electronic Cigarette and Cigarette Use. Pediatrics. 2015 Aug; 136(2):308-17. View in: PubMed

McConnell R, Shen E, Gilliland FD, Jerrett M, Wolch J, Chang CC, Lurmann F, Berhane K. A Longitudinal Cohort Study of Body Mass Index and Childhood Exposure to Secondhand Tobacco Smoke and Air Pollution: The Southern California Children's Health Study. Environ Health Perspect. 2015 Apr; 123(4):360-6. View in: PubMed

Dzubur E, Li M, Kawabata K, Sun Y, McConnell R, Intille S, Dunton GF. Design of a smartphone application to monitor stress, asthma symptoms, and asthma inhaler use. Ann Allergy Asthma Immunol. 2015 Apr; 114(4):341-342. e2. View in: PubMed

Gauderman WJ, Urman R, Avol E, Berhane K, McConnell R, Rappaport E, Chang R, Lurmann F, Gilliland F. Association of improved air quality with lung development in children. N Engl J Med. 2015 Mar 5; 372(10):905-13. View in: PubMed

Barrington-Trimis JL, Samet JM, McConnell R. Flavorings in electronic cigarettes: an unrecognized respiratory health hazard? JAMA. 2014 Dec 17; 312(23):2493-4. View in: PubMed

Urman R, McConnell R, Islam T, Avol EL, Lurmann FW, Vora H, Linn WS, Rappaport EB, Gilliland FD, Gauderman WJ. Associations of children's lung function with ambient air pollution: joint effects of regional and near-roadway pollutants. Thorax. 2014 Jun; 69(6):540-7. View in: PubMed

Dueker D, Taher M, Wilson J, McConnell R. Evaluating children's location using a personal GPS logging instrument: limitations and lessons learned. J Expo Sci Environ Epidemiol. 2014 May; 24(3):244-52. View in: PubMed

Volk HE, Kerin T, Lurmann F, Hertz-Picciotto I, McConnell R, Campbell DB. Autism Spectrum Disorder: Interaction of Air Pollution with the MET Receptor Tyrosine Kinase Gene. Epidemiology. 2014 Jan; 25(1):44-7. View in: PubMed

McConnell R, Wu W, Berhane K, Liu F, Verma G, Peden D, Diaz-Sanchez D, Fruin S. Inflammatory cytokine response to ambient particles varies due to field collection procedures. Am J Respir Cell Mol Biol. 2013 Apr; 48(4):497-502. View in: PubMed

Volk HE, Lurmann F, Penfold B, Hertz-Picciotto I, McConnell R. Traffic-related air pollution, particulate matter, and autism. JAMA Psychiatry. 2013 Jan; 70(1):71-7. View in: PubMed

Davis DA, Bortolato M, Godar SC, Sander TK, Iwata N, Pakbin P, Shih JC, Berhane K, McConnell R, Sioutas C, Finch CE, Morgan TE. Prenatal exposure to urban air nanoparticles in mice causes altered neuronal differentiation and depression-like responses. PLoS One. 2013; 8(5):e64128. View in: PubMed

Dueker D, Gauderman WJ, McConnell R. Accuracy of a new time-resolved step counter in children. Pediatr Exerc Sci. 2012 Nov; 24(4):622-33. View in: PubMed

Breton CV, Wang X, Mack WJ, Berhane K, Lopez M, Islam TS, Feng M, Lurmann F, McConnell R, Hodis HN, Künzli N, Avol E. Childhood air pollutant exposure and carotid artery intima-media thickness in young adults. Circulation. 2012 Sep 25; 126(13):1614-20. View in: PubMed

Dunton G, McConnell R, Jerrett M, Wolch J, Lam C, Gilliland F, Berhane K. Organized physical activity in young school children and subsequent 4-year change in body mass index. Arch Pediatr Adolesc Med. 2012 Aug 1; 166(8):713-8. View in: PubMed

Franklin M, Vora H, Avol E, McConnell R, Lurmann F, Liu F, Penfold B, Berhane K, Gilliland F, Gauderman WJ. Predictors of intra-community variation in air quality. J Expo Sci Environ Epidemiol. 2012 Mar; 22(2):135-47. View in: PubMed

Islam T, Urman R, Gauderman WJ, Milam J, Lurmann F, Shankardass K, Avol E, Gilliland F, McConnell R. Parental stress increases the detrimental effect of traffic exposure on children's lung function. Am J Respir Crit Care Med. 2011 Oct 1; 184(7):822-7. View in: PubMed

Volk HE, Hertz-Picciotto I, Delwiche L, Lurmann F, McConnell R. Residential proximity to freeways and autism in the CHARGE study. Environ Health Perspect. 2011 Jun; 119(6):873-7. View in: PubMed

Zhang Y, McConnell R, Gilliland F, Berhane K. Ethnic differences in the effect of asthma on pulmonary function in children. Am J Respir Crit Care Med. 2011 Mar 1; 183(5):596-603. View in: PubMed

McConnell R, Liu F, Wu J, Lurmann F, Peters J, Berhane K. Asthma and school commuting time. J Occup Environ Med. 2010 Aug; 52(8):827-8. View in: PubMed

McConnell R, Islam T, Shankardass K, Jerrett M, Lurmann F, Gilliland F, Gauderman J, Avol E, Künzli N, Yao L, Peters J, Berhane K. Childhood incident asthma and traffic-related air pollution at home and school. Environ Health Perspect. 2010 Jul; 118(7):1021-6. View in: PubMed

Islam T, Breton C, Salam MT, McConnell R, Wenten M, Gauderman WJ, Conti D, Van Den Berg D, Peters JM, Gilliland FD. Role of inducible nitric oxide synthase in asthma risk and lung function growth during adolescence. Thorax. 2010 Feb; 65(2):139-45. View in: PubMed

Shoakazemi A, Flannery T, McConnell RS. Long-term outcome of subcutaneously preserved autologous cranioplasty. Neurosurgery. 2009 Sep; 65(3):505-10; discussion 510. View in: PubMed

Milam J, McConnell R, Yao L, Berhane K, Jerrett M, Richardson J. Parental stress and childhood wheeze in a prospective cohort study. J Asthma. 2008 May; 45(4):319-23. View in: PubMed

Caird J, Flynn P, McConnell RS. Significant clinical and radiological resolution of a spinal cord syrinx following the release of a tethered cord in a patient with an anatomically normal conus medullaris. Case report. J Neurosurg Pediatr. 2008 May; 1(5):396-8. View in: PubMed

Cozen W, Avol E, Diaz-Sanchez D, McConnell R, Gauderman WJ, Cockburn MG, Zadnick J, Jyrala M, Mack TM. Use of an electrostatic dust cloth for self-administered home allergen collection. Twin Res Hum Genet. 2008 Apr; 11(2):150-5. View in: PubMed

Islam T, McConnell R, Gauderman WJ, Avol E, Peters JM, Gilliland FD. Ozone, oxidant defense genes, and risk of asthma during adolescence. Am J Respir Crit Care Med. 2008 Feb 15; 177(4):388-95. View in: PubMed

Salam MT, Gauderman WJ, McConnell R, Lin PC, Gilliland FD. Transforming growth factor- 1 C-509T polymorphism, oxidant stress, and early-onset childhood asthma. Am J Respir Crit Care Med. 2007 Dec 15; 176(12):1192-9. View in: PubMed

Islam T, Gauderman WJ, Berhane K, McConnell R, Avol E, Peters JM, Gilliland FD. Relationship between air pollution, lung function and asthma in adolescents. Thorax. 2007 Nov; 62(11):957-63. View in: PubMed

Shankardass K, McConnell RS, Milam J, Berhane K, Tatalovich Z, Wilson JP, Jerrett M. The association between contextual socioeconomic factors and prevalent asthma in a cohort of Southern California school children. Soc Sci Med. 2007 Oct; 65(8):1792-806. View in: PubMed

Gauderman WJ, Vora H, McConnell R, Berhane K, Gilliland F, Thomas D, Lurmann F, Avol E, Kunzli N, Jerrett M, Peters J. Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study. Lancet. 2007 Feb 17; 369(9561):571-7. View in: PubMed

McConnell R, Berhane K, Molitor J, Gilliland F, Künzli N, Thorne PS, Thomas D, Gauderman WJ, Avol E, Lurmann F, Rappaport E, Jerrett M, Peters JM. Dog ownership enhances symptomatic responses to air pollution in children with asthma. Environ Health Perspect. 2006 Dec; 114(12):1910-5. View in: PubMed

Künzli N, Avol E, Wu J, Gauderman WJ, Rappaport E, Millstein J, Bennion J, McConnell R, Gilliland FD, Berhane K, Lurmann F, Winer A, Peters JM. Health effects of the 2003 Southern California wildfires on children. Am J Respir Crit Care Med. 2006 Dec 1; 174(11):1221-8. View in: PubMed

Gilliland FD, Islam T, Berhane K, Gauderman WJ, McConnell R, Avol E, Peters JM. Regular smoking and asthma incidence in adolescents. Am J Respir Crit Care Med. 2006 Nov 15; 174(10):1094-100. View in: PubMed

Flannery T, McQuaid S, McGoohan C, McConnell RS, McGregor G, Mirakhur M, Hamilton P, Diamond J, Cran G, Walker B, Scott C, Martin L, Ellison D, Patel C, Nicholson C, Mendelow D, McCormick D, Johnston PG. Cathepsin S expression: An independent prognostic factor in glioblastoma tumours--A pilot study. Int J Cancer. 2006 Aug 15; 119(4):854-60. View in: PubMed

Molitor J, Molitor NT, Jerrett M, McConnell R, Gauderman J, Berhane K, Thomas D. Bayesian modeling of air pollution health effects with missing exposure data. Am J Epidemiol. 2006 Jul 1; 164(1):69-76. View in: PubMed

McConnell R, Berhane K, Yao L, Lurmann FW, Avol E, Peters JM. Predicting residential ozone deficits from nearby traffic. Sci Total Environ. 2006 Jun 15; 363(1-3):166-74. View in: PubMed

Salam MT, Margolis HG, McConnell R, McGregor JA, Avol EL, Gilliland FD. Mode of delivery is associated with asthma and allergy occurrences in children. Ann Epidemiol. 2006 May; 16(5):341-6. View in: PubMed

McConnell R, Berhane K, Yao L, Jerrett M, Lurmann F, Gilliland F, Künzli N, Gauderman J, Avol E, Thomas D, Peters J. Traffic, susceptibility, and childhood asthma. Environ Health Perspect. 2006 May; 114(5):766-72. View in: PubMed

Tatalovich Z, Wilson JP, Milam JE, Jerrett ML, McConnell R. Competing definitions of contextual environments. Int J Health Geogr. 2006; 5:55. View in: PubMed

Wenten M, Berhane K, Rappaport EB, Avol E, Tsai WW, Gauderman WJ, McConnell R, Dubeau L, Gilliland FD. TNF-308 modifies the effect of second-hand smoke on respiratory illness-related school absences. Am J Respir Crit Care Med. 2005 Dec 15; 172(12):1563-8. View in: PubMed

Gauderman WJ, Avol E, Lurmann F, Kuenzli N, Gilliland F, Peters J, McConnell R. Childhood asthma and exposure to traffic and nitrogen dioxide. Epidemiology. 2005 Nov; 16(6):737-43. View in: PubMed

Gilliland F, Avol E, Kinney P, Jerrett M, Dvonch T, Lurmann F, Buckley T, Breysse P, Keeler G, de Villiers T, McConnell R. Air pollution exposure assessment for epidemiologic studies of pregnant women and children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research. Environ Health Perspect. 2005 Oct; 113(10):1447-54. View in: PubMed

Thorne PS, Metwali N, Avol E, McConnell RS. Surface sampling for endotoxin assessment using electrostatic wiping cloths. Ann Occup Hyg. 2005 Jul; 49(5):401-6. View in: PubMed

McConnell R, Milam J, Richardson J, Galvan J, Jones C, Thorne PS, Berhane K. Educational intervention to control cockroach allergen exposure in the homes of hispanic children in Los Angeles: results of the La Casa study. Clin Exp Allergy. 2005 Apr; 35(4):426-33. View in: PubMed

Millstein J, Gilliland F, Berhane K, Gauderman WJ, McConnell R, Avol E, Rappaport EB, Peters JM. Effects of ambient air pollutants on asthma medication use and wheezing among fourth-grade school children from 12 Southern California communities enrolled in The Children's Health Study. Arch Environ Health. 2004 Oct; 59(10):505-14. View in: PubMed

Gauderman WJ, Avol E, Gilliland F, Vora H, Thomas D, Berhane K, McConnell R, Kuenzli N, Lurmann F, Rappaport E, Margolis H, Bates D, Peters J. The effect of air pollution on lung development from 10 to 18 years of age. N Engl J Med. 2004 Sep 9; 351(11):1057-67. View in: PubMed

Richardson JL, Milam JE, Galvan J, Jones C, McConnell R. Knowledge of skin test results among parents of asthmatic children. J Asthma. 2004 Apr; 41(2):199-204. View in: PubMed

McConnell R, Jones C, Milam J, Gonzalez P, Berhane K, Clement L, Richardson J, Hanley-Lopez J, Kwong K, Maalouf N, Galvan J, Platts-Mills T. Cockroach counts and house dust allergen concentrations after professional cockroach control and cleaning. Ann Allergy Asthma Immunol. 2003 Dec; 91(6):546-52. View in: PubMed

McConnell R, Berhane K, Gilliland F, Molitor J, Thomas D, Lurmann F, Avol E, Gauderman WJ, Peters JM. Prospective study of air pollution and bronchitic symptoms in children with asthma. Am J Respir Crit Care Med. 2003 Oct 1; 168(7):790-7. View in: PubMed

Gilliland FD, Berhane KT, Li YF, Gauderman WJ, McConnell R, Peters J. Children's lung function and antioxidant vitamin, fruit, juice, and vegetable intake. Am J Epidemiol. 2003 Sep 15; 158(6):576-84. View in: PubMed

Gilliland FD, Berhane K, Islam T, McConnell R, Gauderman WJ, Gilliland SS, Avol E, Peters JM. Obesity and the risk of newly diagnosed asthma in school-age children. Am J Epidemiol. 2003 Sep 1; 158(5):406-15. View in: PubMed

Künzli N, McConnell R, Bates D, Bastain T, Hricko A, Lurmann F, Avol E, Gilliland F, Peters J. Breathless in Los Angeles: the exhausting search for clean air. Am J Public Health. 2003 Sep; 93(9):1494-9. View in: PubMed

Gilliland FD, Li YF, Dubeau L, Berhane K, Avol E, McConnell R, Gauderman WJ, Peters JM. Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children. Am J Respir Crit Care Med. 2002 Aug 15; 166(4):457-63. View in: PubMed

Gilliland FD, Rappaport EB, Berhane K, Islam T, Dubeau L, Gauderman WJ, McConnell R. Effects of glutathione S-transferase P1, M1, and T1 on acute respiratory illness in school children. Am J Respir Crit Care Med. 2002 Aug 1; 166(3):346-51. View in: PubMed

Gauderman WJ, Gilliland GF, Vora H, Avol E, Stram D, McConnell R, Thomas D, Lurmann F, Margolis HG, Rappaport EB, Berhane K, Peters JM. Association between air pollution and lung function growth in southern California children: results from a second cohort. Am J Respir Crit Care Med. 2002 Jul 1; 166(1):76-84. View in: PubMed

McConnell R, Berhane K, Gilliland F, Islam T, Gauderman WJ, London SJ, Avol E, Rappaport EB, Margolis HG, Peters JM. Indoor risk factors for asthma in a prospective study of adolescents. Epidemiology. 2002 May; 13(3):288-95. View in: PubMed

McConnell R, Berhane K, Gilliland F, London SJ, Islam T, Gauderman WJ, Avol E, Margolis HG, Peters JM. Asthma in exercising children exposed to ozone: a cohort study. Lancet. 2002 Feb 2; 359(9304):386-91. View in: PubMed

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