Faculty

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Ryoichi Sakiyama
Postdoctoral Scholar Research Associate
Biochemistry and Molecular Biology
HMR 2011 Zonal Avenue, Rm 509, MC9091 Health Sciences Campus Los Angeles

Publications

Sakiyama R, Yamamoto K, Ishimori I, Yoshida S, Akiba T, Mineshima M. Performance evaluation of developed polysulfone membrane hemodiafilters, ABH-F and ABH-P, in post- and pre-dilution hemodiafiltration. J Artif Organs. 2015 Dec; 18(4):330-7. View in: PubMed

Kato T, Sakiyama R, Oka K, Nakamura T. Identification of core active disaccharides in heparin for HGF-inducing activity. J Pharmacol Pharmacother. 2015 Apr-Jun; 6(2):77-82. View in: PubMed

Sakiyama R, Ishimori I, Akiba T, Mineshima M. Effect of blood flow rate on internal filtration in a high-flux dialyzer with polysulfone membrane. J Artif Organs. 2012 Sep; 15(3):266-71. View in: PubMed

Mineshima M, Ishimori I, Sakiyama R. Validity of internal filtration-enhanced hemodialysis as a new hemodiafiltration therapy. Blood Purif. 2009; 27(1):33-7. View in: PubMed

Sakiyama R, Fukuta K, Matsumoto K, Furukawa M, Takahashi Y, Nakamura T. Stimulation of hepatocyte growth factor production by heparin-derived oligosaccharides. J Biochem. 2007 May; 141(5):653-60. View in: PubMed

Shimada M, Yamashita Y, Tanaka S, Shirabe K, Nakazawa K, Ijima H, Sakiyama R, Fukuda J, Funatsu K, Sugimachi K. Characteristic gene expression induced by polyurethane foam/spheroid culture of hepatoma cell line, Hep G2 as a promising cell source for bioartificial liver. Hepatogastroenterology. 2007 Apr-May; 54(75):814-20. View in: PubMed

Yamashita Y, Shimada M, Tsujita E, Shirabe K, Ijima H, Nakazawa K, Sakiyama R, Fukuda J, Funatsu K, Sugimachi K. Efficacy of a larger version of the hybrid artificial liver support system using a polyurethane foam/spheroid packed-bed module in a warm ischemic liver failure pig model for preclinical experiments. Cell Transplant. 2003; 12(2):101-7. View in: PubMed

Sakiyama R, Nakazawa K, Ijima H, Mizumoto H, Kajiwara T, Ito M, Ishibashi H, Funatsu K. Recovery of rats with fulminant hepatic failure by using a hybrid artificial liver support system with polyurethane foam/rat hepatocyte spheroids. Int J Artif Organs. 2002 Dec; 25(12):1144-52. View in: PubMed

Yamashita Y, Shimada M, Tsujita E, Shirabe K, Ijima H, Nakazawa K, Sakiyama R, Fukuda J, Funatsu K, Sugimachi K. High metabolic function of primary human and porcine hepatocytes in a polyurethane foam/spheroid culture system in plasma from patients with fulminant hepatic failure. Cell Transplant. 2002; 11(4):379-84. View in: PubMed

Nakazawa K, Ijima H, Fukuda J, Sakiyama R, Yamashita Y, Shimada M, Shirabe K, Tsujita E, Sugimachi K, Funatsu K. Development of a hybrid artificial liver using polyurethane foam/hepatocyte spheroid culture in a preclinical pig experiment. Int J Artif Organs. 2002 Jan; 25(1):51-60. View in: PubMed

Fukuda J, Sakiyama R, Nakazawa K, Ijima H, Yamashita Y, Shimada M, Shirabe K, Tsujita E, Sugimachi K, Funatsu K. Mass preparation of primary porcine hepatocytes and the design of a hybrid artificial liver module using spheroid culture for a clinical trial. Int J Artif Organs. 2001 Nov; 24(11):799-806. View in: PubMed

Yamashita Y, Shimada M, Tsujita E, Tanaka S, Ijima H, Nakazawa K, Sakiyama R, Fukuda J, Ueda T, Funatsu K, Sugimachi K. Polyurethane foam/spheroid culture system using human hepatoblastoma cell line (Hep G2) as a possible new hybrid artificial liver. Cell Transplant. 2001; 10(8):717-22. View in: PubMed

Yamashita Y, Shimada M, Tsujita E, Rikimaru T, Ijima H, Nakazawa K, Sakiyama R, Fukuda J, Funatsu K, Sugimachi K. The efficacy of nafamostat mesilate on the performance of a hybrid-artificial liver using a polyurethane foam/porcine hepatocyte spheroid culture system in human plasma. Int J Artif Organs. 2001 Jan; 24(1):34-40. View in: PubMed

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