Faculty

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Thomas G Keens, MD
Professor of Pediatrics
Pediatrics
CHL Mail Stop 83 Off Campus Los Angeles
+1 323 361 2101

Overview

An expert on respiratory and pulmonary disorders in children, including sudden infant death syndrome

Awards

Listed in The Best Doctors in America

Board of Directors, American Board of Pediatrics: Subspecialist representative member

Fellow of American Academy of Pediatrics and American College of Chest Physicians

Chair of California Sudden Infant Death Syndrome Advisory Council

Publications

Salinas DB, Azen C, Young S, Keens TG, Kharrazi M, Parad RB. Phenotypes of California CF Newborn Screen-Positive Children with CFTR 5T Allele by TG Repeat Length. Genet Test Mol Biomarkers. 2016 Sep; 20(9):496-503. View in: PubMed

Edwards JD, Houtrow AJ, Lucas AR, Miller RL, Keens TG, Panitch HB, Dudley RA. Children and Young Adults Who Received Tracheostomies or Were Initiated on Long-Term Ventilation in PICUs. Pediatr Crit Care Med. 2016 Aug; 17(8):e324-34. View in: PubMed

Ackerman MJ, Andrew TA, Baker AM, Devinsky O, Downs JC, Keens T, Kuntz J, Lin P, Lear-Kaul KC, Reichard R, Robinson DA. An Association of Hippocampal Malformations and Sudden Death? We Need More Data. Forensic Sci Med Pathol. 2016 Jun; 12(2):229-31. View in: PubMed

Stastny PF, Keens TG, Alkon A. Supporting SIDS Families: The Public Health Nurse SIDS Home Visit. Public Health Nurs. 2016 May; 33(3):242-8. View in: PubMed

Perez IA, Kun S, Keens TG. PATIENT EDUCATION | INFORMATION SERIES. Diaphragm Pacing by Phrenic Nerve Stimulation. Am J Respir Crit Care Med. 2016 Apr 15; 193(8):P13-4. View in: PubMed

Salinas DB, Sosnay PR, Azen C, Young S, Raraigh KS, Keens TG, Kharrazi M. Benign and Deleterious Cystic Fibrosis Transmembrane Conductance Regulator Mutations Identified by Sequencing in Positive Cystic Fibrosis Newborn Screen Children from California. PLoS One. 2016; 11(5):e0155624. View in: PubMed

Salinas DB, Sosnay PR, Azen C, Young S, Raraigh KS, Keens TG, Kharrazi M. Benign outcome among positive cystic fibrosis newborn screen children with non-CF-causing variants. J Cyst Fibros. 2015 Nov; 14(6):714-9. View in: PubMed

De A, Mascarenhas L, Kamath S, LaRiviere A, Goodarzian F, Keens TG, Venkatramani R. Pilot Feasibility Study of Comprehensive Pulmonary Evaluation Following Lung Radiation Therapy. J Pediatr Hematol Oncol. 2015 Oct; 37(7):e412-8. View in: PubMed

Kun SS, Beas VN, Keens TG, Ward SS, Gold JI. Examining pediatric emergency home ventilation practices in home health nurses: Opportunities for improved care. Pediatr Pulmonol. 2015 Jul; 50(7):691-7. View in: PubMed

De A, Kamath S, Wong K, Olch AJ, Malvar J, Sposto R, Mascarenhas L, Keens TG, Venkatramani R. Correlation of pulmonary function abnormalities with dose volume histograms in children treated with lung irradiation. Pediatr Pulmonol. 2015 Jun; 50(6):596-603. View in: PubMed

Diep B, Wang A, Kun S, McComb JG, Shaul DB, Shin CE, Keens TG, Perez IA. Diaphragm Pacing without Tracheostomy in Congenital Central Hypoventilation Syndrome Patients. Respiration. 2015 Apr 25. View in: PubMed

Chin CI, Kohn SL, Keens TG, Margetis MF, Kato RM. A physician survey reveals differences in management of idiopathic pulmonary hemosiderosis. Orphanet J Rare Dis. 2015; 10(1):98. View in: PubMed

Bhatia R, Lesser DJ, Oliveira FG, Tran WH, Keens TG, Khoo MC, Davidson Ward SL. Body Fat Composition: A Predictive Factor for Sleep Related Breathing Disorder in Obese Children. J Clin Sleep Med. 2015; 11(9):1039-45. View in: PubMed

Nicholson KJ, Nosanov LB, Bowen KA, Kun SS, Perez IA, Keens TG, Shin CE. Thoracoscopic placement of phrenic nerve pacers for diaphragm pacing in congenital central hypoventilation syndrome. J Pediatr Surg. 2015 Jan; 50(1):78-81. View in: PubMed

De A, Guryev I, LaRiviere A, Kato R, Wee CP, Mascarenhas L, Keens TG, Venkatramani R. Pulmonary function abnormalities in childhood cancer survivors treated with bleomycin. Pediatr Blood Cancer. 2014 Sep; 61(9):1679-84. View in: PubMed

Venkatramani R, Kamath S, Wong K, Olch AJ, Malvar J, Sposto R, Goodarzian F, Freyer DR, Keens TG, Mascarenhas L. Pulmonary outcomes in patients with Hodgkin lymphoma treated with involved field radiation. Pediatr Blood Cancer. 2014 Jul; 61(7):1277-81. View in: PubMed

Weese-Mayer DE, Berry-Kravis EM, Ceccherini I, Keens TG, Loghmanee DA, Trang H. [ATS clinical policy statement: Congenital central hypoventilation syndrome. Genetic basis, diagnosis and management]. Rev Mal Respir. 2013 Oct; 30(8):706-33. View in: PubMed

Venkatramani R, Kamath S, Wong K, Olch AJ, Malvar J, Sposto R, Goodarzian F, Freyer DR, Keens TG, Mascarenhas L. Correlation of clinical and dosimetric factors with adverse pulmonary outcomes in children after lung irradiation. Int J Radiat Oncol Biol Phys. 2013 Aug 1; 86(5):942-8. View in: PubMed

Sohn EY, Kato R, Noetzli LJ, Gera A, Coates T, Harmatz P, Keens TG, Wood JC. Exercise performance in thalassemia major: correlation with cardiac iron burden. Am J Hematol. 2013 Mar; 88(3):193-7. View in: PubMed

Perez IA, Keens TG. Peripheral chemoreceptors in congenital central hypoventilation syndrome. Respir Physiol Neurobiol. 2013 Jan 1; 185(1):186-93. View in: PubMed

Jassal MS, Yu AM, Bhatia R, Keens TG, Davidson Ward SL. Effect of residential proximity to major roadways on cystic fibrosis exacerbations. Int J Environ Health Res. 2013; 23(2):119-31. View in: PubMed

Yuan HC, Sohn EY, Abouezzeddine T, Mahrer NE, Barber BA, Keens TG, Davidson Ward SL, Gold JI. Neurocognitive functioning in children with obstructive sleep apnea syndrome: a pilot study of positive airway pressure therapy. J Pediatr Nurs. 2012 Dec; 27(6):607-13. View in: PubMed

Lesser DJ, Bhatia R, Tran WH, Oliveira F, Ortega R, Keens TG, Mittelman SD, Khoo MC, Davidson Ward SL. Sleep fragmentation and intermittent hypoxemia are associated with decreased insulin sensitivity in obese adolescent Latino males. Pediatr Res. 2012 Sep; 72(3):293-8. View in: PubMed

Kun SS, Edwards JD, Davidson Ward SL, Keens TG. Hospital readmissions for newly discharged pediatric home mechanical ventilation patients. Pediatr Pulmonol. 2012 Apr; 47(4):409-14. View in: PubMed

Edwards JD, Kun SS, Graham RJ, Keens TG. End-of-life discussions and advance care planning for children on long-term assisted ventilation with life-limiting conditions. J Palliat Care. 2012; 28(1):21-7. View in: PubMed

Sohn EY, Noetzli LJ, Gera A, Kato R, Coates TD, Harmatz P, Keens TG, Wood JC. Pulmonary function in thalassaemia major and its correlation with body iron stores. Br J Haematol. 2011 Oct; 155(1):102-5. View in: PubMed

Sangkatumvong S, Khoo MC, Kato R, Detterich JA, Bush A, Keens TG, Meiselman HJ, Wood JC, Coates TD. Peripheral vasoconstriction and abnormal parasympathetic response to sighs and transient hypoxia in sickle cell disease. Am J Respir Crit Care Med. 2011 Aug 15; 184(4):474-81. View in: PubMed

Edwards JD, Rivanis C, Kun SS, Caughey AB, Keens TG. Costs of hospitalized ventilator-dependent children: differences between a ventilator ward and intensive care unit. Pediatr Pulmonol. 2011 Apr; 46(4):356-61. View in: PubMed

Edwards JD, Kun SS, Keens TG. Outcomes and causes of death in children on home mechanical ventilation via tracheostomy: an institutional and literature review. J Pediatr. 2010 Dec; 157(6):955-959. e2. View in: PubMed

Edwards JD, Kun SS, Keens TG, Khemani RG, Moromisato DY. Children with corrected or palliated congenital heart disease on home mechanical ventilation. Pediatr Pulmonol. 2010 Jul; 45(7):645-9. View in: PubMed

Weese-Mayer DE, Berry-Kravis EM, Ceccherini I, Keens TG, Loghmanee DA, Trang H. An official ATS clinical policy statement: Congenital central hypoventilation syndrome: genetic basis, diagnosis, and management. Am J Respir Crit Care Med. 2010 Mar 15; 181(6):626-44. View in: PubMed

Keens TG. Postdoctoral fellowship training in pediatric pulmonology in the United States of America. Paediatr Respir Rev. 2010 Mar; 11(1):66-7. View in: PubMed

Kun SS, Davidson-Ward SL, Hulse LM, Keens TG. How much do primary care givers know about tracheostomy and home ventilator emergency care? Pediatr Pulmonol. 2010 Mar; 45(3):270-4. View in: PubMed

Lesser DJ, Fleming MM, Maher CA, Kim SB, Woo MS, Keens TG. Does the 6-min walk test correlate with the exercise stress test in children? Pediatr Pulmonol. 2010 Feb; 45(2):135-40. View in: PubMed

Oliveira FM, Tran WH, Lesser D, Bhatia R, Ortega R, Mittelman SD, Keens TG, Davidson Ward SL, Khoo MC. Autonomic and metabolic effects of OSA in childhood obesity. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:6134-7. View in: PubMed

Kun WW, Kun SS, Keens TG. Do sequential chest radiographs prompt changes in therapy for home mechanical ventilation children admitted for pneumonia? Care Manag J. 2010; 11(4):217-9. View in: PubMed

Chaicharn J, Lin Z, Chen ML, Ward SL, Keens T, Khoo MC. Model-based assessment of cardiovascular autonomic control in children with obstructive sleep apnea. Sleep. 2009 Jul; 32(7):927-38. View in: PubMed

Lesser DJ, Ward SL, Kun SS, Keens TG. Congenital hypoventilation syndromes. Semin Respir Crit Care Med. 2009 Jun; 30(3):339-47. View in: PubMed

Chang RK, Keens TG, Rodriguez S, Chen AY. Sudden infant death syndrome: changing epidemiologic patterns in California 1989-2004. J Pediatr. 2008 Oct; 153(4):498-502. View in: PubMed

Tablizo MA, Jacinto P, Parsley D, Chen ML, Ramanathan R, Keens TG. Supine sleeping position does not cause clinical aspiration in neonates in hospital newborn nurseries. Arch Pediatr Adolesc Med. 2007 May; 161(5):507-10. View in: PubMed

Claudius I, Keens T. Do all infants with apparent life-threatening events need to be admitted? Pediatrics. 2007 Apr; 119(4):679-83. View in: PubMed

Chen ML, Turkel SB, Jacobson JR, Keens TG. Alcohol use in congenital central hypoventilation syndrome. Pediatr Pulmonol. 2006 Mar; 41(3):283-5. View in: PubMed

Chaicharn J, Lin Z, Chen ML, Keens TG, Davidson Ward SL, Khoo MK. Time-varying closed-loop modeling of autonomic control in pediatric obstructive sleep apnea syndrome during cold face stimulation. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:3569-71. View in: PubMed

Yuan N, Skaggs DL, Dorey F, Keens TG. Preoperative predictors of prolonged postoperative mechanical ventilation in children following scoliosis repair. Pediatr Pulmonol. 2005 Nov; 40(5):414-9. View in: PubMed

Chen ML, Tablizo MA, Kun S, Keens TG. Diaphragm pacers as a treatment for congenital central hypoventilation syndrome. Expert Rev Med Devices. 2005 Sep; 2(5):577-85. View in: PubMed

Kumar R, Macey PM, Woo MA, Alger JR, Keens TG, Harper RM. Neuroanatomic deficits in congenital central hypoventilation syndrome. J Comp Neurol. 2005 Jul 11; 487(4):361-71. View in: PubMed

Chen ML, Witmans MB, Tablizo MA, Jubran RF, Turkel SB, Tavaré CJ, Keens TG. Disordered respiratory control in children with partial cerebellar resections. Pediatr Pulmonol. 2005 Jul; 40(1):88-91. View in: PubMed

Woo MA, Macey PM, Macey KE, Keens TG, Woo MS, Harper RK, Harper RM. FMRI responses to hyperoxia in congenital central hypoventilation syndrome. Pediatr Res. 2005 Apr; 57(4):510-8. View in: PubMed

Macey PM, Macey KE, Woo MA, Keens TG, Harper RM. Aberrant neural responses to cold pressor challenges in congenital central hypoventilation syndrome. Pediatr Res. 2005 Apr; 57(4):500-9. View in: PubMed

Harper RM, Macey PM, Woo MA, Macey KE, Keens TG, Gozal D, Alger JR. Hypercapnic exposure in congenital central hypoventilation syndrome reveals CNS respiratory control mechanisms. J Neurophysiol. 2005 Mar; 93(3):1647-58. View in: PubMed

Macey PM, Woo MA, Macey KE, Keens TG, Saeed MM, Alger JR, Harper RM. Hypoxia reveals posterior thalamic, cerebellar, midbrain, and limbic deficits in congenital central hypoventilation syndrome. J Appl Physiol. 2005 Mar; 98(3):958-69. View in: PubMed

Lynn Chen M, Davidson Ward SL, Keens T, Lin Z, K Khoo M. Cardio-respiratory Uncoupling in Congenital Central Hypoventilation Syndrome. Conf Proc IEEE Eng Med Biol Soc. 2005; 4:4412-5. View in: PubMed

Lin Z, K Khoo M, Chen M, Keens T, Davidson Ward SL. Noninvasive assessment of cardiovascular autonomic control in pediatric obstructive sleep apnea syndrome. Conf Proc IEEE Eng Med Biol Soc. 2005; 1:776-9. View in: PubMed

Lin Z, K Khoo M, Chen M, Keens T, Davidson Ward SL. Noninvasive assessment of cardiovascular autonomic control in pediatric obstructive sleep apnea syndrome. Conf Proc IEEE Eng Med Biol Soc. 2005; 4:4416-9. View in: PubMed

Hamutcu R, Nield TA, Garg M, Keens TG, Platzker AC. Long-term pulmonary sequelae in children who were treated with extracorporeal membrane oxygenation for neonatal respiratory failure. Pediatrics. 2004 Nov; 114(5):1292-6. View in: PubMed

Macey KE, Macey PM, Woo MA, Harper RK, Alger JR, Keens TG, Harper RM. fMRI signal changes in response to forced expiratory loading in congenital central hypoventilation syndrome. J Appl Physiol. 2004 Nov; 97(5):1897-907. View in: PubMed

Yuan N, Skaggs DL, Davidson Ward SL, Platzker AC, Keens TG. Preoperative polysomnograms and infant pulmonary function tests do not predict prolonged postoperative mechanical ventilation in children following scoliosis repair. Pediatr Pulmonol. 2004 Sep; 38(3):256-60. View in: PubMed

Chen ML, Keens TG. Congenital central hypoventilation syndrome: not just another rare disorder. Paediatr Respir Rev. 2004 Sep; 5(3):182-9. View in: PubMed

Krous HF, Beckwith JB, Byard RW, Rognum TO, Bajanowski T, Corey T, Cutz E, Hanzlick R, Keens TG, Mitchell EA. Sudden infant death syndrome and unclassified sudden infant deaths: a definitional and diagnostic approach. Pediatrics. 2004 Jul; 114(1):234-8. View in: PubMed

Macey PM, Valderama C, Kim AH, Woo MA, Gozal D, Keens TG, Harper RK, Harper RM. Temporal trends of cardiac and respiratory responses to ventilatory challenges in congenital central hypoventilation syndrome. Pediatr Res. 2004 Jun; 55(6):953-9. View in: PubMed

Stastny PF, Ichinose TY, Thayer SD, Olson RJ, Keens TG. Infant sleep positioning by nursery staff and mothers in newborn hospital nurseries. Nurs Res. 2004 Mar-Apr; 53(2):122-9. View in: PubMed

Lin Z, Chen ML, Keens TG, Ward SL, Khoo MC. Noninvasive assessment of cardiovascular autonomic control in congenital central hypoventilation syndrome. Conf Proc IEEE Eng Med Biol Soc. 2004; 5:3870-3. View in: PubMed

Witmans MB, Keens TG, Davidson Ward SL, Marcus CL. Obstructive hypopneas in children and adolescents: normal values. Am J Respir Crit Care Med. 2003 Dec 15; 168(12):1540. View in: PubMed

Ner Z, Ross LA, Horn MV, Keens TG, MacLaughlin EF, Starnes VA, Woo MS. Bordetella bronchiseptica infection in pediatric lung transplant recipients. Pediatr Transplant. 2003 Oct; 7(5):413-7. View in: PubMed

Sritippayawan S, Keens TG, Horn MV, Starnes VA, Woo MS. What are the best pulmonary function test parameters for early detection of post-lung transplant bronchiolitis obliterans syndrome in children? Pediatr Transplant. 2003 Jun; 7(3):200-3. View in: PubMed

Sritippayawan S, Kun SS, Keens TG, Davidson Ward SL. Initiation of home mechanical ventilation in children with neuromuscular diseases. J Pediatr. 2003 May; 142(5):481-5. View in: PubMed

Sritippayawan S, Keens TG, Horn MV, MacLaughlin EF, Barr ML, Starnes VA, Woo MS. Does lung growth occur when mature lobes are transplanted into children? Pediatr Transplant. 2002 Dec; 6(6):500-4. View in: PubMed

Sritippayawan S, Hamutcu R, Kun SS, Ner Z, Ponce M, Keens TG. Mother-daughter transmission of congenital central hypoventilation syndrome. Am J Respir Crit Care Med. 2002 Aug 1; 166(3):367-9. View in: PubMed

Shaul DB, Danielson PD, McComb JG, Keens TG. Thoracoscopic placement of phrenic nerve electrodes for diaphragmatic pacing in children. J Pediatr Surg. 2002 Jul; 37(7):974-8; discussion 974-8. View in: PubMed

Nakamura CT, Ng GY, Paton JY, Keens TG, Witmer JC, Bautista-Bolduc D, Woo MS. Correlation between digital clubbing and pulmonary function in cystic fibrosis. Pediatr Pulmonol. 2002 May; 33(5):332-8. View in: PubMed

Ramanathan R, Corwin MJ, Hunt CE, Lister G, Tinsley LR, Baird T, Silvestri JM, Crowell DH, Hufford D, Martin RJ, Neuman MR, Weese-Mayer DE, Cupples LA, Peucker M, Willinger M, Keens TG. Cardiorespiratory events recorded on home monitors: Comparison of healthy infants with those at increased risk for SIDS. JAMA. 2001 May 2; 285(17):2199-207. View in: PubMed

Nakamura CT, Ripka JF, McVeigh K, Kapoor N, Keens TG. Bronchoscopic instillation of surfactant in acute respiratory distress syndrome. Pediatr Pulmonol. 2001 Apr; 31(4):317-20. View in: PubMed

Kun SS, Nakamura CT, Ripka JF, Davidson Ward SL, Keens TG. Home ventilator low-pressure alarms fail to detect accidental decannulation with pediatric tracheostomy tubes. Chest. 2001 Feb; 119(2):562-4. View in: PubMed

Nakamura CT, Ferdman RM, Keens TG, Davidson Ward SL. Latex allergy in children on home mechanical ventilation. Chest. 2000 Oct; 118(4):1000-3. View in: PubMed

Saeed MM, Keens TG, Stabile MW, Bolokowicz J, Davidson Ward SL. Should children with suspected obstructive sleep apnea syndrome and normal nap sleep studies have overnight sleep studies? Chest. 2000 Aug; 118(2):360-5. View in: PubMed

Hunt CE, Corwin MJ, Lister G, Weese-Mayer DE, Neuman MR, Tinsley L, Baird TM, Keens TG, Cabral HJ. Longitudinal assessment of hemoglobin oxygen saturation in healthy infants during the first 6 months of age. Collaborative Home Infant Monitoring Evaluation (CHIME) Study Group. J Pediatr. 1999 Nov; 135(5):580-6. View in: PubMed

Saeed MM, Woo MS, MacLaughlin EF, Margetis MF, Keens TG. Prognosis in pediatric idiopathic pulmonary hemosiderosis. Chest. 1999 Sep; 116(3):721-5. View in: PubMed

Mittler MA, Keens TG, McComb JG. Image of the month: Joubert syndrome. Pediatr Neurosurg. 1999 Apr; 30(4):218. View in: PubMed

Srinivasan S, Doty SM, White TR, Segura VH, Jansen MT, Davidson Ward SL, Keens TG. Frequency, causes, and outcome of home ventilator failure. Chest. 1998 Nov; 114(5):1363-7. View in: PubMed

Willinger M, Hoffman HJ, Wu KT, Hou JR, Kessler RC, Ward SL, Keens TG, Corwin MJ. Factors associated with the transition to nonprone sleep positions of infants in the United States: the National Infant Sleep Position Study. JAMA. 1998 Jul 22-29; 280(4):329-35. View in: PubMed

Make BJ, Hill NS, Goldberg AI, Bach JR, Criner GJ, Dunne PE, Gilmartin ME, Heffner JE, Kacmarek R, Keens TG, McInturff S, O'Donohue WJ, Oppenheimer EA, Robert D. Mechanical ventilation beyond the intensive care unit. Report of a consensus conference of the American College of Chest Physicians. Chest. 1998 May; 113(5 Suppl):289S-344S. View in: PubMed

Shah AR, Gozal D, Keens TG. Determinants of aerobic and anaerobic exercise performance in cystic fibrosis. Am J Respir Crit Care Med. 1998 Apr; 157(4 Pt 1):1145-50. View in: PubMed

Ambrosio IU, Woo MS, Jansen MT, Keens TG. Safety of hospitalized ventilator-dependent children outside of the intensive care unit. Pediatrics. 1998 Feb; 101(2):257-9. View in: PubMed

Shah AR, Keens TG, Gozal D. Effect of supplemental oxygen on supramaximal exercise performance and recovery in cystic fibrosis. J Appl Physiol. 1997 Nov; 83(5):1641-7. View in: PubMed

Wen AS, Woo MS, Keens TG. How many maneuvers are required to measure maximal inspiratory pressure accurately. Chest. 1997 Mar; 111(3):802-7. View in: PubMed

Gozal D, Marcus CL, Ward SL, Keens TG. Ventilatory responses to passive leg motion in children with congenital central hypoventilation syndrome. Am J Respir Crit Care Med. 1996 Feb; 153(2):761-8. View in: PubMed

Arens R, Gozal D, Burrell BC, Bailey SL, Bautista DB, Keens TG, Ward SL. Arousal and cardiorespiratory responses to hypoxia in Prader-Willi syndrome. Am J Respir Crit Care Med. 1996 Jan; 153(1):283-7. View in: PubMed

Aljadeff G, Gozal D, Bailey-Wahl SL, Burrell B, Keens TG, Ward SL. Effects of overnight supplemental oxygen in obstructive sleep apnea in children. Am J Respir Crit Care Med. 1996 Jan; 153(1):51-5. View in: PubMed

Livingston FR, Arens R, Bailey SL, Keens TG, Ward SL. Hypercapnic arousal responses in Prader-Willi syndrome. Chest. 1995 Dec; 108(6):1627-31. View in: PubMed

Gozal D, Arens R, Omlin KJ, Ben-Ari JH, Aljadeff G, Harper RM, Keens TG. Ventilatory response to consecutive short hypercapnic challenges in children with obstructive sleep apnea. J Appl Physiol. 1995 Nov; 79(5):1608-14. View in: PubMed

Kugelman A, Keens TG, deLemos R, Durand M. Comparison of dynamic and passive measurements of respiratory mechanics in ventilated newborn infants. Pediatr Pulmonol. 1995 Oct; 20(4):258-64. View in: PubMed

Gozal D, Arens R, Omlin KJ, Jacobs RA, Keens TG. Peripheral chemoreceptor function in children with myelomeningocele and Arnold-Chiari malformation type 2. Chest. 1995 Aug; 108(2):425-31. View in: PubMed

Gozal D, Ben-Ari JH, Harper RM, Keens TG. Ventilatory responses to repeated short hypercapnic challenges. J Appl Physiol. 1995 Apr; 78(4):1374-81. View in: PubMed

Gozal D, Arens R, Omlin KJ, Ward SL, Keens TG. Absent peripheral chemosensitivity in Prader-Willi syndrome. J Appl Physiol. 1994 Nov; 77(5):2231-6. View in: PubMed

Arens R, Gozal D, Omlin KJ, Livingston FR, Liu J, Keens TG, Ward SL. Hypoxic and hypercapnic ventilatory responses in Prader-Willi syndrome. J Appl Physiol. 1994 Nov; 77(5):2224-30. View in: PubMed

Arens R, Gozal D, Omlin KJ, Vega J, Boyd KP, Keens TG, Woo MS. Comparison of high frequency chest compression and conventional chest physiotherapy in hospitalized patients with cystic fibrosis. Am J Respir Crit Care Med. 1994 Oct; 150(4):1154-7. View in: PubMed

Keens TG, Oki GS, Gilsanz V, Roe TF, Goodman W, Tsang RC, Specker BL, Saenger EL. Does radiation research in healthy children pose greater than minimal risk? IRB. 1994 Sep-Oct; 16(5):5-10. View in: PubMed

Keens TG, Ward SL. SIDS research. Science. 1994 May 20; 264(5162):1065. View in: PubMed

Gozal D, Arens R, Omlin KJ, Marcus CL, Keens TG. Maturational differences in step vs. ramp hypoxic and hypercapnic ventilatory responses. J Appl Physiol. 1994 May; 76(5):1968-75. View in: PubMed

Marcus CL, Gozal D, Arens R, Basinski DJ, Omlin KJ, Keens TG, Ward SL. Ventilatory responses during wakefulness in children with obstructive sleep apnea. Am J Respir Crit Care Med. 1994 Mar; 149(3 Pt 1):715-21. View in: PubMed

Gozal D, Lorey FW, Chandler D, Derry MK, Lisbin A, Keens TG, Cunningham GC, Ward SL. Incidence of sudden infant death syndrome in infants with sickle cell trait. J Pediatr. 1994 Feb; 124(2):211-4. View in: PubMed

Marcus CL, Glomb WB, Basinski DJ, Davidson SL, Keens TG. Developmental pattern of hypercapnic and hypoxic ventilatory responses from childhood to adulthood. J Appl Physiol. 1994 Jan; 76(1):314-20. View in: PubMed

Gozal D, Bailey SL, Keens TG. Evolution of pulmonary function during an acute exacerbation in hospitalized patients with cystic fibrosis. Pediatr Pulmonol. 1993 Dec; 16(6):347-53. View in: PubMed

Keens TG, Ward SL. Apnea spells, sudden death, and the role of the apnea monitor. Pediatr Clin North Am. 1993 Oct; 40(5):897-911. View in: PubMed

Arens R, Gozal D, Williams JC, Ward SL, Keens TG. Recurrent apparent life-threatening events during infancy: a manifestation of inborn errors of metabolism. J Pediatr. 1993 Sep; 123(3):415-8. View in: PubMed

Arens R, Gozal D, Jain K, Muscati S, Heuser ET, Williams JC, Keens TG, Ward SL. Prevalence of medium-chain acyl-coenzyme A dehydrogenase deficiency in the sudden infant death syndrome. J Pediatr. 1993 May; 122(5 Pt 1):715-8. View in: PubMed

Paton JY, Swaminathan S, Sargent CW, Hawksworth A, Keens TG. Ventilatory response to exercise in children with congenital central hypoventilation syndrome. Am Rev Respir Dis. 1993 May; 147(5):1185-91. View in: PubMed

DeWitt PK, Jansen MT, Ward SL, Keens TG. Obstacles to discharge of ventilator-assisted children from the hospital to home. Chest. 1993 May; 103(5):1560-5. View in: PubMed

Gozal D, Shoseyov D, Keens TG. Inspiratory pressures with CO2 stimulation and weaning from mechanical ventilation in children. Am Rev Respir Dis. 1993 Feb; 147(2):256-61. View in: PubMed

Gozal D, Marcus CL, Shoseyov D, Keens TG. Peripheral chemoreceptor function in children with the congenital central hypoventilation syndrome. J Appl Physiol. 1993 Jan; 74(1):379-87. View in: PubMed

Ward SL, Keens TG. Prenatal substance abuse. Clin Perinatol. 1992 Dec; 19(4):849-60. View in: PubMed

Swaminathan S, Paton JY, Ward SL, Sargent CW, Keens TG. Theophylline does not increase ventilatory responses to hypercapnia or hypoxia. Am Rev Respir Dis. 1992 Dec; 146(6):1398-401. View in: PubMed

Marcus CL, Omlin KJ, Basinki DJ, Bailey SL, Rachal AB, Von Pechmann WS, Keens TG, Ward SL. Normal polysomnographic values for children and adolescents. Am Rev Respir Dis. 1992 Nov; 146(5 Pt 1):1235-9. View in: PubMed

Glomb WB, Marcus CL, Keens TG, Ward SL. Hypercapnic and hypoxic ventilatory and cardiac responses in school-aged siblings of sudden infant death syndrome victims. J Pediatr. 1992 Sep; 121(3):391-7. View in: PubMed

Gilgoff IS, Peng RC, Keens TG. Hypoventilation and apnea in children during mechanically assisted ventilation. Chest. 1992 Jun; 101(6):1500-6. View in: PubMed

Ward SL, Bautista DB, Keens TG. Hypoxic arousal responses in normal infants. Pediatrics. 1992 May; 89(5 Pt 1):860-4. View in: PubMed

Marcus CL, Keens TG, Ward SL. Comparison of nap and overnight polysomnography in children. Pediatr Pulmonol. 1992 May; 13(1):16-21. View in: PubMed

Garg M, Kurzner SI, Bautista DB, Lew CD, Ramos AD, Platzker AC, Keens TG. Pulmonary sequelae at six months following extracorporeal membrane oxygenation. Chest. 1992 Apr; 101(4):1086-90. View in: PubMed

Woo MS, Woo MA, Gozal D, Jansen MT, Keens TG, Harper RM. Heart rate variability in congenital central hypoventilation syndrome. Pediatr Res. 1992 Mar; 31(3):291-6. View in: PubMed

Marcus CL, Bader D, Stabile MW, Wang CI, Osher AB, Keens TG. Supplemental oxygen and exercise performance in patients with cystic fibrosis with severe pulmonary disease. Chest. 1992 Jan; 101(1):52-7. View in: PubMed

Marcus CL, Jansen MT, Poulsen MK, Keens SE, Nield TA, Lipsker LE, Keens TG. Medical and psychosocial outcome of children with congenital central hypoventilation syndrome. J Pediatr. 1991 Dec; 119(6):888-95. View in: PubMed

Marcus CL, Bautista DB, Amihyia A, Ward SL, Keens TG. Hypercapneic arousal responses in children with congenital central hypoventilation syndrome. Pediatrics. 1991 Nov; 88(5):993-8. View in: PubMed

Garg M, Lew CD, Ramos AD, Platzker AC, Keens TG. Serial measurement of pulmonary mechanics assists in weaning from extracorporeal membrane oxygenation in neonates with respiratory failure. Chest. 1991 Sep; 100(3):770-4. View in: PubMed

Marcus CL, Keens TG, Bautista DB, von Pechmann WS, Ward SL. Obstructive sleep apnea in children with Down syndrome. Pediatrics. 1991 Jul; 88(1):132-9. View in: PubMed

Marcus CL, Livingston FR, Wood SE, Keens TG. Hypercapnic and hypoxic ventilatory responses in parents and siblings of children with congenital central hypoventilation syndrome. Am Rev Respir Dis. 1991 Jul; 144(1):136-40. View in: PubMed

Paton JY, Bautista DB, Stabile MW, Waldman AE, Nassar AG, Platzker AC, Keens TG. Digital clubbing and pulmonary function abnormalities in children with lung disease. Pediatr Pulmonol. 1991; 10(1):25-9. View in: PubMed

Sivan Y, Ward SD, Deakers T, Keens TG, Newth CJ. Rib cage to abdominal asynchrony in children undergoing polygraphic sleep studies. Pediatr Pulmonol. 1991; 11(2):141-6. View in: PubMed

Ward SL, Bautista D, Chan L, Derry M, Lisbin A, Durfee MJ, Mills KS, Keens TG. Sudden infant death syndrome in infants of substance-abusing mothers. J Pediatr. 1990 Dec; 117(6):876-81. View in: PubMed

Gilgoff IS, Kahlstrom E, MacLaughlin E, Keens TG. Long-term ventilatory support in spinal muscular atrophy. J Pediatr. 1989 Dec; 115(6):904-9. View in: PubMed

Swaminathan S, Paton JY, Ward SL, Jacobs RA, Sargent CW, Keens TG. Abnormal control of ventilation in adolescents with myelodysplasia. J Pediatr. 1989 Dec; 115(6):898-903. View in: PubMed

Paton JY, Swaminathan S, Sargent CW, Keens TG. Hypoxic and hypercapnic ventilatory responses in awake children with congenital central hypoventilation syndrome. Am Rev Respir Dis. 1989 Aug; 140(2):368-72. View in: PubMed

Swaminathan S, Gilsanz V, Atkinson J, Keens TG. Congenital central hypoventilation syndrome associated with multiple ganglioneuromas. Chest. 1989 Aug; 96(2):423-4. View in: PubMed

Swaminathan S, Quinn J, Stabile MW, Bader D, Platzker AC, Keens TG. Long-term pulmonary sequelae of meconium aspiration syndrome. J Pediatr. 1989 Mar; 114(3):356-61. View in: PubMed

Jansen MT, DeWitt PK, Meshul RJ, Krasnoff JB, Lau AM, Keens TG. Meeting psychosocial and developmental needs of children during prolonged intensive care unit hospitalization. Child Health Care. 1989; 18(2):91-5. View in: PubMed

Glenn WW, Brouillette RT, Dentz B, Fodstad H, Hunt CE, Keens TG, Marsh HM, Pande S, Piepgras DG, Vanderlinden RG. Fundamental considerations in pacing of the diaphragm for chronic ventilatory insufficiency: a multi-center study. Pacing Clin Electrophysiol. 1988 Nov; 11(11 Pt 2):2121-7. View in: PubMed

Durrani FK, Richards W, Church JA, Roberts MJ, Keens TG. Evaluation of a new, shorter method of administration of adrenergic aerosols in the treatment of asthma. Ann Allergy. 1988 Aug; 61(2):147-50. View in: PubMed

Garg M, Kurzner SI, Bautista D, Keens TG. Hypoxic arousal responses in infants with bronchopulmonary dysplasia. Pediatrics. 1988 Jul; 82(1):59-63. View in: PubMed

Garg M, Kurzner SI, Bautista DB, Keens TG. Clinically unsuspected hypoxia during sleep and feeding in infants with bronchopulmonary dysplasia. Pediatrics. 1988 May; 81(5):635-42. View in: PubMed

Kurzner SI, Garg M, Bautista DB, Bader D, Merritt RJ, Warburton D, Keens TG. Growth failure in infants with bronchopulmonary dysplasia: nutrition and elevated resting metabolic expenditure. Pediatrics. 1988 Mar; 81(3):379-84. View in: PubMed

Kurzner SI, Garg M, Bautista DB, Sargent CW, Bowman CM, Keens TG. Growth failure in bronchopulmonary dysplasia: elevated metabolic rates and pulmonary mechanics. J Pediatr. 1988 Jan; 112(1):73-80. View in: PubMed

Bader D, Ramos AD, Lew CD, Platzker AC, Stabile MW, Keens TG. Childhood sequelae of infant lung disease: exercise and pulmonary function abnormalities after bronchopulmonary dysplasia. J Pediatr. 1987 May; 110(5):693-9. View in: PubMed

Keens TG, Ward SL, Gates EP, Hart LD, Basile A, Tinajero LA, Lau AM, Chan CE. A comparison of pneumogram recordings in infants in the hospital and at home. Pediatr Pulmonol. 1986 Nov-Dec; 2(6):373-7. View in: PubMed

Ward SL, Jacobs RA, Gates EP, Hart LD, Keens TG. Abnormal ventilatory patterns during sleep in infants with myelomeningocele. J Pediatr. 1986 Oct; 109(4):631-4. View in: PubMed

Ward SL, Schuetz S, Kirshna V, Bean X, Wingert W, Wachsman L, Keens TG. Abnormal sleeping ventilatory pattern in infants of substance-abusing mothers. Am J Dis Child. 1986 Oct; 140(10):1015-20. View in: PubMed

O'Donohue WJ, Giovannoni RM, Goldberg AI, Keens TG, Make BJ, Plummer AL, Prentice WS. Long-term mechanical ventilation. Guidelines for management in the home and at alternate community sites. Report of the Ad Hoc Committee, Respiratory Care Section, American College of Chest Physicians. Chest. 1986 Jul; 90(1 Suppl):1S-37S. View in: PubMed

Ward SL, Nickerson BG, van der Hal A, Rodriguez AM, Jacobs RA, Keens TG. Absent hypoxic and hypercapneic arousal responses in children with myelomeningocele and apnea. Pediatrics. 1986 Jul; 78(1):44-50. View in: PubMed

Ward SL, Keens TG, Chan LS, Chipps BE, Carson SH, Deming DD, Krishna V, MacDonald HM, Martin GI, Meredith KS, et al. Sudden infant death syndrome in infants evaluated by apnea programs in California. Pediatrics. 1986 Apr; 77(4):451-8. View in: PubMed

Ortega JA, Stowe SM, Shore NA, Keens TG, Woolley MM. Prevention of radiation pneumonitis by controlled pneumothorax in childhood rhabdomyosarcoma of the chest wall. Int J Radiat Oncol Biol Phys. 1985 Nov; 11(11):2033-4. View in: PubMed

Keens TG, Ward SL, Gates EP, Andree DI, Hart LD. Ventilatory pattern following diphtheria-tetanus-pertussis immunization in infants at risk for sudden infant death syndrome. Am J Dis Child. 1985 Oct; 139(10):991-4. View in: PubMed

Kao LC, Keens TG. Decreased specific airway conductance in infant apnea. Pediatrics. 1985 Aug; 76(2):232-5. View in: PubMed

van der Hal AL, Rodriguez AM, Sargent CW, Platzker AC, Keens TG. Hypoxic and hypercapneic arousal responses and prediction of subsequent apnea in apnea of infancy. Pediatrics. 1985 May; 75(5):848-54. View in: PubMed

Nava-Guerra L, Tran WH, Chalacheva P, Loloyan S, Joshi B, Keens TG, Nayak KS, Davidson Ward SL, Khoo MC. Model-based stability assessment of ventilatory control in overweight adolescents with obstructive sleep apnea during NREM sleep. J Appl Physiol (1985). 2016 Jul 1; 121(1):185-97. View in: PubMed

Kao LC, Warburton D, Cheng MH, Cedeño C, Platzker AC, Keens TG. Effect of oral diuretics on pulmonary mechanics in infants with chronic bronchopulmonary dysplasia: results of a double-blind crossover sequential trial. Pediatrics. 1984 Jul; 74(1):37-44. View in: PubMed

Kao LC, Warburton D, Platzker AC, Keens TG. Effect of isoproterenol inhalation on airway resistance in chronic bronchopulmonary dysplasia. Pediatrics. 1984 Apr; 73(4):509-14. View in: PubMed

Buckingham BA, Uitto J, Sandborg C, Keens T, Roe T, Costin G, Kaufman F, Bernstein B, Landing B, Castellano A. Scleroderma-like changes in insulin-dependent diabetes mellitus: clinical and biochemical studies. Diabetes Care. 1984 Mar-Apr; 7(2):163-9. View in: PubMed

Kao LC, Warburton D, Sargent CW, Platzker AC, Keens TG. Furosemide acutely decreases airways resistance in chronic bronchopulmonary dysplasia. J Pediatr. 1983 Oct; 103(4):624-9. View in: PubMed

Scott CB, Nickerson BG, Sargent CW, Platzker AC, Warburton D, Keens TG. Developmental pattern of maximal transdiaphragmatic pressure in infants during crying. Pediatr Res. 1983 Sep; 17(9):707-9. View in: PubMed

Nickerson BG, Bautista DB, Namey MA, Richards W, Keens TG. Distance running improves fitness in asthmatic children without pulmonary complications or changes in exercise-induced bronchospasm. Pediatrics. 1983 Feb; 71(2):147-52. View in: PubMed

Scott CB, Nickerson BG, Sargent CW, Dennies PC, Platzker AC, Keens TG. Diaphragm strength in near-miss sudden infant death syndrome. Pediatrics. 1982 Jun; 69(6):782-4. View in: PubMed

Lam DS, Ramos AD, Platzker AC, Warburton D, Keens TG. Paralysis of diaphragm complicating central venous alimentation. Am J Dis Child. 1981 Apr; 135(4):382. View in: PubMed

Schonfeld T, O'Neal MH, Platzker AC, Weitzman JJ, Fishman LS, Whiteman S, Keens TG. Function of the diaphragm before and after plication. Thorax. 1980 Aug; 35(8):631-2. View in: PubMed

Keens TG, O'Neal MH, Ortega JA, Hyman CB, Platzker AC. Pulmonary function abnormalities in thalassemia patients on a hypertransfusion program. Pediatrics. 1980 May; 65(5):1013-7. View in: PubMed

Schonfeld T, Sargent CW, Bautista D, Walters MA, O'Neal MH, Platzker AC, Keens TG. Transcutaneous oxygen monitoring during exercise stress testing. Am Rev Respir Dis. 1980 Mar; 121(3):457-62. View in: PubMed

Wesley JR, Keens TG, Miller SW, Platzker AC. Pulmonary embolism in the neonate: occurrence during the course of total parenteral nutrition. J Pediatr. 1978 Jul; 93(1):113-5. View in: PubMed

Mellis CM, Kattan M, Keens TG, Levison H. Comparative study of histamine and exercise challenges in asthmatic children. Am Rev Respir Dis. 1978 May; 117(5):911-5. View in: PubMed

Kattan M, Keens TG, Mellis CM, Levison H. The response to exercise in normal and asthmatic children. J Pediatr. 1978 May; 92(5):718-21. View in: PubMed

Wong JW, Keens TG, Wannamaker EM, Crozier DN, Levison H, Aspin N. Effects of gravity on tracheal mucus transport rates in normal subjects and in patients with cystic fibrosis. Pediatrics. 1977 Aug; 60(2):146-52. View in: PubMed

Kattan M, Keens TG, Lapierre JG, Levison H, Bryan AC, Reilly BJ. Pulmonary function abnormalities in symptom-free children after bronchiolitis. Pediatrics. 1977 May; 59(5):683-8. View in: PubMed

Yuan N, Fraire JA, Margetis MM, Skaggs DL, Tolo VT, Keens TG. The effect of scoliosis surgery on lung function in the immediate postoperative period. Spine (Phila Pa 1976). 2005 Oct 1; 30(19):2182-5. View in: PubMed

Codsi MJ, Keens TG, Stein JE, Miyasaka K, Skaggs DL. Respiratory failure in postpneumonectomy syndrome complicated by thoracic lordoscoliosis: treatment with prosthetic implants, partial vertebrectomies, and spinal fusion. Spine (Phila Pa 1976). 2000 Oct 1; 25(19):2531-6. View in: PubMed

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