Faculty

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Vicente Gilsanz, MD
Professor of Radiology
Pediatrics
CHL Mail Stop 81 Off Campus Los Angeles
+1 323 361 4571

Publications

Ponrartana S, Fisher CL, Aggabao PC, Chavez TA, Broom AM, Wren TA, Skaggs DL, Gilsanz V. Small vertebral cross-sectional area and tall intervertebral disc in adolescent idiopathic scoliosis. Pediatr Radiol. 2016 Sep; 46(10):1424-9. View in: PubMed

Mitchell JA, Chesi A, McCormack SE, Roy SM, Cousminer DL, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Zemel BS, Grant SF. Rare EN1 Variants and Pediatric Bone Mass. J Bone Miner Res. 2016 Aug; 31(8):1513-7. View in: PubMed

Mitchell JA, Chesi A, Elci O, McCormack SE, Roy SM, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Grant SF, Zemel BS. Physical Activity Benefits the Skeleton of Children Genetically Predisposed to Lower Bone Density in Adulthood. J Bone Miner Res. 2016 Aug; 31(8):1504-12. View in: PubMed

Ponrartana S, Aggabao PC, Chavez TA, Dharmavaram NL, Gilsanz V. Changes in Brown Adipose Tissue and Muscle Development during Infancy. J Pediatr. 2016 Jun; 173:116-21. View in: PubMed

Mitchell JA, Chesi A, Elci O, McCormack SE, Roy SM, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Grant SF, Zemel BS. Genetic Risk Scores Implicated in Adult Bone Fragility Associate With Pediatric Bone Density. J Bone Miner Res. 2016 Apr; 31(4):789-95. View in: PubMed

Kim MS, Dao-Tran A, Davidowitz E, Tseng T, Gilsanz V, Ryabets-Lienhard A, Nguyen E, Geffner ME. Carotid Intima-Media Thickness Is Associated with Increased Androgens in Adolescents and Young Adults with Classical Congenital Adrenal Hyperplasia. Horm Res Paediatr. 2016; 85(4):242-9. View in: PubMed

Medina-Gómez C, Chesi A, Heppe DH, Zemel BS, Yin JL, Kalkwarf HJ, Hofman A, Lappe JM, Kelly A, Kayser M, Oberfield SE, Gilsanz V, Uitterlinden AG, Shepherd JA, Jaddoe VW, Grant SF, Lao O, Rivadeneira F. BMD Loci Contribute to Ethnic and Developmental Differences in Skeletal Fragility across Populations: Assessment of Evolutionary Selection Pressures. Mol Biol Evol. 2015 Nov; 32(11):2961-72. View in: PubMed

Arkader A, Woon RP, Gilsanz V. Can Subclinical Rickets Cause SCFE? A Prospective, Pilot Study. J Pediatr Orthop. 2015 Oct-Nov; 35(7):e72-5. View in: PubMed

Chesi A, Mitchell JA, Kalkwarf HJ, Bradfield JP, Lappe JM, McCormack SE, Gilsanz V, Oberfield SE, Hakonarson H, Shepherd JA, Kelly A, Zemel BS, Grant SF. A trans-ethnic genome-wide association study identifies gender-specific loci influencing pediatric aBMD and BMC at the distal radius. Hum Mol Genet. 2015 Sep 1; 24(17):5053-9. View in: PubMed

Mitchell JA, Chesi A, Elci O, McCormack SE, Kalkwarf HJ, Lappe JM, Gilsanz V, Oberfield SE, Shepherd JA, Kelly A, Zemel BS, Grant SF. Genetics of Bone Mass in Childhood and Adolescence: Effects of Sex and Maturation Interactions. J Bone Miner Res. 2015 Sep; 30(9):1676-83. View in: PubMed

Xie B, Avila JI, Ng BK, Fan B, Loo V, Gilsanz V, Hangartner T, Kalkwarf HJ, Lappe J, Oberfield S, Winer K, Zemel B, Shepherd JA. Accurate body composition measures from whole-body silhouettes. Med Phys. 2015 Aug; 42(8):4668. View in: PubMed

Kim MS, Ryabets-Lienhard A, Dao-Tran A, Mittelman SD, Gilsanz V, Schrager SM, Geffner ME. Increased Abdominal Adiposity in Adolescents and Young Adults With Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency. J Clin Endocrinol Metab. 2015 Aug; 100(8):E1153-9. View in: PubMed

Ponrartana S, Aggabao PC, Dharmavaram NL, Fisher CL, Friedlich P, Devaskar SU, Gilsanz V. Sexual Dimorphism in Newborn Vertebrae and Its Potential Implications. J Pediatr. 2015 Aug; 167(2):416-21. View in: PubMed

Ponrartana S, Ramos-Platt L, Wren TA, Hu HH, Perkins TG, Chia JM, Gilsanz V. Effectiveness of diffusion tensor imaging in assessing disease severity in Duchenne muscular dystrophy: preliminary study. Pediatr Radiol. 2015 Apr; 45(4):582-9. View in: PubMed

Ollberding NJ, Gilsanz V, Lappe JM, Oberfield SE, Shepherd JA, Winer KK, Zemel BS, Kalkwarf HJ. Reproducibility and intermethod reliability of a calcium food frequency questionnaire for use in Hispanic, non-Hispanic black, and non-Hispanic white youth. J Acad Nutr Diet. 2015 Apr; 115(4):519-527. e2. View in: PubMed

Kremer R, Gilsanz V. Fat and Bone: An Odd Couple. Front Endocrinol (Lausanne). 2015; 6:190. View in: PubMed

Lappe JM, Watson P, Gilsanz V, Hangartner T, Kalkwarf HJ, Oberfield S, Shepherd J, Winer KK, Zemel B. The longitudinal effects of physical activity and dietary calcium on bone mass accrual across stages of pubertal development. J Bone Miner Res. 2015 Jan; 30(1):156-64. View in: PubMed

Güller I, McNaughton S, Crowley T, Gilsanz V, Kajimura S, Watt M, Russell AP. Comparative analysis of microRNA expression in mouse and human brown adipose tissue. BMC Genomics. 2015; 16(1):820. View in: PubMed

Kim MS, Hu HH, Aggabao PC, Geffner ME, Gilsanz V. Presence of brown adipose tissue in an adolescent with severe primary hypothyroidism. J Clin Endocrinol Metab. 2014 Sep; 99(9):E1686-90. View in: PubMed

Kelly A, Winer KK, Kalkwarf H, Oberfield SE, Lappe J, Gilsanz V, Zemel BS. Age-Based Reference Ranges for Annual Height Velocity in US Children. J Clin Endocrinol Metab. 2014 Jun; 99(6):2104-12. View in: PubMed

Ponrartana S, Andrade KE, Wren TA, Ramos-Platt L, Hu HH, Bluml S, Gilsanz V. Repeatability of chemical-shift-encoded water-fat MRI and diffusion-tensor imaging in lower extremity muscles in children. AJR Am J Roentgenol. 2014 Jun; 202(6):W567-73. View in: PubMed

Wren TA, Kalkwarf HJ, Zemel BS, Lappe JM, Oberfield S, Shepherd JA, Winer KK, Gilsanz V. Longitudinal Tracking of Dual-Energy X-ray Absorptiometry Bone Measures Over 6 Years in Children and Adolescents: Persistence of Low Bone Mass to Maturity. J Pediatr. 2014 Jun; 164(6):1280-1285. e2. View in: PubMed

Hu HH, Wu TW, Yin L, Kim MS, Chia JM, Perkins TG, Gilsanz V. MRI detection of brown adipose tissue with low fat content in newborns with hypothermia. Magn Reson Imaging. 2014 Feb; 32(2):107-17. View in: PubMed

Ponrartana S, Patil S, Aggabao PC, Pavlova Z, Devaskar SU, Gilsanz V. Brown Adipose Tissue in the Buccal Fat Pad during Infancy. PLoS One. 2014; 9(2):e89533. View in: PubMed

Hu HH, Yin L, Aggabao PC, Perkins TG, Chia JM, Gilsanz V. Comparison of brown and white adipose tissues in infants and children with chemical-shift-encoded water-fat MRI. J Magn Reson Imaging. 2013 Oct; 38(4):885-96. View in: PubMed

Ponrartana S, Hu HH, Gilsanz V. On the relevance of brown adipose tissue in children. Ann N Y Acad Sci. 2013 Oct; 1302(1):24-9. View in: PubMed

Bacchetta J, Wesseling-Perry K, Gilsanz V, Gales B, Pereira RC, Salusky IB. Idiopathic juvenile osteoporosis: a cross-sectional single-centre experience with bone histomorphometry and quantitative computed tomography. Pediatr Rheumatol Online J. 2013; 11:6. View in: PubMed

Hu HH, Perkins TG, Chia JM, Gilsanz V. Characterization of human brown adipose tissue by chemical-shift water-fat MRI. AJR Am J Roentgenol. 2013 Jan; 200(1):177-83. View in: PubMed

Gilsanz V, Hu HH, Kajimura S. Relevance of brown adipose tissue in infancy and adolescence. Pediatr Res. 2013 Jan; 73(1):3-9. View in: PubMed

Wren TA, Shepherd JA, Kalkwarf HJ, Zemel BS, Lappe JM, Oberfield S, Dorey FJ, Winer KK, Gilsanz V. Racial disparity in fracture risk between white and nonwhite children in the United States. J Pediatr. 2012 Dec; 161(6):1035-40. View in: PubMed

Ponrartana S, Aggabao PC, Hu HH, Aldrovandi GM, Wren TA, Gilsanz V. Brown adipose tissue and its relationship to bone structure in pediatric patients. J Clin Endocrinol Metab. 2012 Aug; 97(8):2693-8. View in: PubMed

Chalfant JS, Smith ML, Hu HH, Dorey FJ, Goodarzian F, Fu CH, Gilsanz V. Inverse association between brown adipose tissue activation and white adipose tissue accumulation in successfully treated pediatric malignancy. Am J Clin Nutr. 2012 May; 95(5):1144-9. View in: PubMed

Gilsanz V, Hu HH, Smith ML, Goodarzian F, Carcich SL, Warburton NM, Malogolowkin M. The depiction of brown adipose tissue is related to disease status in pediatric patients with lymphoma. AJR Am J Roentgenol. 2012 Apr; 198(4):909-13. View in: PubMed

Hu HH, Tovar JP, Pavlova Z, Smith ML, Gilsanz V. Unequivocal identification of brown adipose tissue in a human infant. J Magn Reson Imaging. 2012 Apr; 35(4):938-42. View in: PubMed

Gilsanz V, Smith ML, Goodarzian F, Kim M, Wren TA, Hu HH. Changes in Brown Adipose Tissue in Boys and Girls during Childhood and Puberty. J Pediatr. 2012 Apr; 160(4):604-609. e1. View in: PubMed

Sharp LZ, Shinoda K, Ohno H, Scheel DW, Tomoda E, Ruiz L, Hu H, Wang L, Pavlova Z, Gilsanz V, Kajimura S. Human BAT possesses molecular signatures that resemble beige/brite cells. PLoS One. 2012; 7(11):e49452. View in: PubMed

Shepherd JA, Wang L, Fan B, Gilsanz V, Kalkwarf HJ, Lappe J, Lu Y, Hangartner T, Zemel BS, Fredrick M, Oberfield S, Winer KK. Optimal monitoring time interval between DXA measures in children. J Bone Miner Res. 2011 Nov; 26(11):2745-52. View in: PubMed

Zemel BS, Kalkwarf HJ, Gilsanz V, Lappe JM, Oberfield S, Shepherd JA, Frederick MM, Huang X, Lu M, Mahboubi S, Hangartner T, Winer KK. Revised reference curves for bone mineral content and areal bone mineral density according to age and sex for black and non-black children: results of the bone mineral density in childhood study. J Clin Endocrinol Metab. 2011 Oct; 96(10):3160-9. View in: PubMed

Gilsanz V, Chung SA, Kaplowitz N. Differential effect of gender on hepatic fat. Pediatr Radiol. 2011 Sep; 41(9):1146-53. View in: PubMed

Wood JC, Mo A, Gera A, Koh M, Coates T, Gilsanz V. Quantitative computed tomography assessment of transfusional iron overload. Br J Haematol. 2011 Jun; 153(6):780-5. View in: PubMed

Gilsanz V, Chung SA, Jackson H, Dorey FJ, Hu HH. Functional brown adipose tissue is related to muscle volume in children and adolescents. J Pediatr. 2011 May; 158(5):722-6. View in: PubMed

Chung SA, Dorey F, Mittelman S, Gilsanz V. Effect of gender on intra-abdominal fat in teenagers and young adults. Pediatr Radiol. 2011 Apr; 41(4):469-75. View in: PubMed

Wren TA, Chung SA, Dorey FJ, Bluml S, Adams GB, Gilsanz V. Bone marrow fat is inversely related to cortical bone in young and old subjects. J Clin Endocrinol Metab. 2011 Mar; 96(3):782-6. View in: PubMed

Al Wren T, Lee DC, Kay RM, Dorey FJ, Gilsanz V. Bone density and size in ambulatory children with cerebral palsy. Dev Med Child Neurol. 2011 Feb; 53(2):137-41. View in: PubMed

Hu HH, Gilsanz V. Developments in the imaging of brown adipose tissue and its associations with muscle, puberty, and health in children. Front Endocrinol (Lausanne). 2011; 2:33. View in: PubMed

Hu HH, Chung SA, Nayak KS, Jackson HA, Gilsanz V. Differential computed tomographic attenuation of metabolically active and inactive adipose tissues: preliminary findings. J Comput Assist Tomogr. 2011 Jan-Feb; 35(1):65-71. View in: PubMed

Gilsanz V, Chalfant J, Kalkwarf H, Zemel B, Lappe J, Oberfield S, Shepherd J, Wren T, Winer K. Age at onset of puberty predicts bone mass in young adulthood. J Pediatr. 2011 Jan; 158(1):100-5, 105. e1-2. View in: PubMed

Wren TA, Lee DC, Hara R, Rethlefsen SA, Kay RM, Dorey FJ, Gilsanz V. Effect of high-frequency, low-magnitude vibration on bone and muscle in children with cerebral palsy. J Pediatr Orthop. 2010 Oct-Nov; 30(7):732-8. View in: PubMed

Suchy FJ, Brannon PM, Carpenter TO, Fernandez JR, Gilsanz V, Gould JB, Hall K, Hui SL, Lupton J, Mennella J, Miller NJ, Osganian SK, Sellmeyer DE, Wolf MA. National Institutes of Health Consensus Development Conference: lactose intolerance and health. Ann Intern Med. 2010 Jun 15; 152(12):792-6. View in: PubMed

Di Iorgi N, Mo AO, Grimm K, Wren TA, Dorey F, Gilsanz V. Bone acquisition in healthy young females is reciprocally related to marrow adiposity. J Clin Endocrinol Metab. 2010 Jun; 95(6):2977-82. View in: PubMed

Kalkwarf HJ, Gilsanz V, Lappe JM, Oberfield S, Shepherd JA, Hangartner TN, Huang X, Frederick MM, Winer KK, Zemel BS. Tracking of bone mass and density during childhood and adolescence. J Clin Endocrinol Metab. 2010 Apr; 95(4):1690-8. View in: PubMed

Gilsanz V, Kremer A, Mo AO, Wren TA, Kremer R. Vitamin D status and its relation to muscle mass and muscle fat in young women. J Clin Endocrinol Metab. 2010 Apr; 95(4):1595-601. View in: PubMed

Mittelman SD, Gilsanz P, Mo AO, Wood J, Dorey F, Gilsanz V. Adiposity predicts carotid intima-media thickness in healthy children and adolescents. J Pediatr. 2010 Apr; 156(4):592-7. e2. View in: PubMed

Zemel BS, Leonard MB, Kelly A, Lappe JM, Gilsanz V, Oberfield S, Mahboubi S, Shepherd JA, Hangartner TN, Frederick MM, Winer KK, Kalkwarf HJ. Height adjustment in assessing dual energy x-ray absorptiometry measurements of bone mass and density in children. J Clin Endocrinol Metab. 2010 Mar; 95(3):1265-73. View in: PubMed

Suchy FJ, Brannon PM, Carpenter TO, Fernandez JR, Gilsanz V, Gould JB, Hall K, Hui SL, Lupton J, Mennella J, Miller NJ, Osganian SK, Sellmeyer DE, Wolf MA. NIH consensus development conference statement: Lactose intolerance and health. NIH Consens State Sci Statements. 2010 Feb 24; 27(2):1-27. View in: PubMed

Wren TA, Gilsanz V. Evolving role of imaging in the evaluation of bone structure. J Bone Miner Res. 2009 Dec; 24(12):1943-5. View in: PubMed

Meeske KA, Siegel SE, Gilsanz V, Bernstein L, Nelson MB, Sposto R, Weaver FA, Lavey RS, Mack MP, Nelson MD. Premature carotid artery disease in pediatric cancer survivors treated with neck irradiation. Pediatr Blood Cancer. 2009 Oct; 53(4):615-21. View in: PubMed

Gilsanz V, Chalfant J, Mo AO, Lee DC, Dorey FJ, Mittelman SD. Reciprocal relations of subcutaneous and visceral fat to bone structure and strength. J Clin Endocrinol Metab. 2009 Sep; 94(9):3387-93. View in: PubMed

Lee DC, Campbell PP, Gilsanz V, Wren TA. Contribution of the vertebral posterior elements in anterior-posterior DXA spine scans in young subjects. J Bone Miner Res. 2009 Aug; 24(8):1398-403. View in: PubMed

Gilsanz V, Perez FJ, Campbell PP, Dorey FJ, Lee DC, Wren TA. Quantitative CT reference values for vertebral trabecular bone density in children and young adults. Radiology. 2009 Jan; 250(1):222-7. View in: PubMed

Luu YK, Capilla E, Rosen CJ, Gilsanz V, Pessin JE, Judex S, Rubin CT. Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietary-induced obesity. J Bone Miner Res. 2009 Jan; 24(1):50-61. View in: PubMed

Kremer R, Campbell PP, Reinhardt T, Gilsanz V. Vitamin D status and its relationship to body fat, final height, and peak bone mass in young women. J Clin Endocrinol Metab. 2009 Jan; 94(1):67-73. View in: PubMed

Di Iorgi N, Rosol M, Mittelman SD, Gilsanz V. Reciprocal relation between marrow adiposity and the amount of bone in the axial and appendicular skeleton of young adults. J Clin Endocrinol Metab. 2008 Jun; 93(6):2281-6. View in: PubMed

Gonzalez J, Wood JC, Dorey FJ, Wren TA, Gilsanz V. Reproducibility of carotid intima-media thickness measurements in young adults. Radiology. 2008 May; 247(2):465-71. View in: PubMed

Wren TA, Bluml S, Tseng-Ong L, Gilsanz V. Three-point technique of fat quantification of muscle tissue as a marker of disease progression in Duchenne muscular dystrophy: preliminary study. AJR Am J Roentgenol. 2008 Jan; 190(1):W8-12. View in: PubMed

Lee DC, Gilsanz V, Wren TA. Limitations of peripheral quantitative computed tomography metaphyseal bone density measurements. J Clin Endocrinol Metab. 2007 Nov; 92(11):4248-53. View in: PubMed

Kalkwarf HJ, Zemel BS, Gilsanz V, Lappe JM, Horlick M, Oberfield S, Mahboubi S, Fan B, Frederick MM, Winer K, Shepherd JA. The bone mineral density in childhood study: bone mineral content and density according to age, sex, and race. J Clin Endocrinol Metab. 2007 Jun; 92(6):2087-99. View in: PubMed

Numbenjapon N, Costin G, Gilsanz V, Pitukcheewanont P. Low cortical bone density measured by computed tomography in children and adolescents with untreated hyperthyroidism. J Pediatr. 2007 May; 150(5):527-30. View in: PubMed

Gilsanz V, Wren T. Assessment of bone acquisition in childhood and adolescence. Pediatrics. 2007 Mar; 119 Suppl 2:S145-9. View in: PubMed

Wren TA, Kim PS, Janicka A, Sanchez M, Gilsanz V. Timing of peak bone mass: discrepancies between CT and DXA. J Clin Endocrinol Metab. 2007 Mar; 92(3):938-41. View in: PubMed

Janicka A, Wren TA, Sanchez MM, Dorey F, Kim PS, Mittelman SD, Gilsanz V. Fat mass is not beneficial to bone in adolescents and young adults. J Clin Endocrinol Metab. 2007 Jan; 92(1):143-7. View in: PubMed

Wren TA, Gilsanz V. Assessing bone mass in children and adolescents. Curr Osteoporos Rep. 2006 Dec; 4(4):153-8. View in: PubMed

Gilsanz V, Wren TA, Sanchez M, Dorey F, Judex S, Rubin C. Low-level, high-frequency mechanical signals enhance musculoskeletal development of young women with low BMD. J Bone Miner Res. 2006 Sep; 21(9):1464-74. View in: PubMed

Klein GL, Fitzpatrick LA, Langman CB, Beck TJ, Carpenter TO, Gilsanz V, Holm IA, Leonard MB, Specker BL. The state of pediatric bone: summary of the ASBMR pediatric bone initiative. J Bone Miner Res. 2005 Dec; 20(12):2075-81. View in: PubMed

Pitukcheewanont P, Safani D, Church J, Gilsanz V. Bone measures in HIV-1 infected children and adolescents: disparity between quantitative computed tomography and dual-energy X-ray absorptiometry measurements. Osteoporos Int. 2005 Nov; 16(11):1393-6. View in: PubMed

Kovanlikaya A, Mittelman SD, Ward A, Geffner ME, Dorey F, Gilsanz V. Obesity and fat quantification in lean tissues using three-point Dixon MR imaging. Pediatr Radiol. 2005 Jun; 35(6):601-7. View in: PubMed

Wren TA, Liu X, Pitukcheewanont P, Gilsanz V. Bone densitometry in pediatric populations: discrepancies in the diagnosis of osteoporosis by DXA and CT. J Pediatr. 2005 Jun; 146(6):776-9. View in: PubMed

Kovanlikaya A, Guclu C, Desai C, Becerra R, Gilsanz V. Fat quantification using three-point dixon technique: in vitro validation. Acad Radiol. 2005 May; 12(5):636-9. View in: PubMed

Wren TA, Liu X, Pitukcheewanont P, Gilsanz V. Bone acquisition in healthy children and adolescents: comparisons of dual-energy x-ray absorptiometry and computed tomography measures. J Clin Endocrinol Metab. 2005 Apr; 90(4):1925-8. View in: PubMed

Sanchez MM, Gilsanz V. Pediatric DXA bone measurements. Pediatr Endocrinol Rev. 2005 Feb; 2 Suppl 3:337-41. View in: PubMed

Schulz E, Arfai K, Liu X, Sayre J, Gilsanz V. Aortic calcification and the risk of osteoporosis and fractures. J Clin Endocrinol Metab. 2004 Sep; 89(9):4246-53. View in: PubMed

Pitukcheewanont P, Safani D, Gilsanz V, Klein M, Chongpison Y, Costin G. Quantitative computed tomography measurements of bone mineral density in prepubertal children with congenital hypothyroidism treated with L-thyroxine. J Pediatr Endocrinol Metab. 2004 Jun; 17(6):889-93. View in: PubMed

Mora S, Gilsanz V. Establishment of peak bone mass. Endocrinol Metab Clin North Am. 2003 Mar; 32(1):39-63. View in: PubMed

Arfai K, Pitukcheewanont PD, Goran MI, Tavare CJ, Heller L, Gilsanz V. Bone, muscle, and fat: sex-related differences in prepubertal children. Radiology. 2002 Aug; 224(2):338-44. View in: PubMed

Keens TG, Oki GS, Gilsanz V, Roe TF, Goodman W, Tsang RC, Specker BL, Saenger EL. Does radiation research in healthy children pose greater than minimal risk? IRB. 1994 Sep-Oct; 16(5):5-10. View in: PubMed

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