Faculty

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Wendy Jean Mack, PhD
Professor of Preventive Medicine
Preventive Medicine
SSB 202Y 2001 N. Soto Street Health Sciences Campus Los Angeles
+1 323 442 1820

Overview

Wendy Mack, PhD, is a professor of biostatistics in the Department of Preventive Medicine at the Keck School of Medicine of USC. She co-directs the department’s Division of Biostatistics graduate programs and directs Biostatistics Resources at the Southern California Clinical and Translational Science Institute (SC CTSI).

Professor Mack has more than 20 years of experience directing biostatistical and data coordination activities, primarily funded by the National Institutes of Health (NIH). Her expertise includes design, conduct and analysis of multiple single-centered and multi-centered clinical trials and observational studies. She also directs biostatistical activities for the USC Alzheimer’s Disease Research Center and for other basic and clinical research programs.

She has served on numerous NIH study sections for biostatistical expertise and has recently completed a term on the NHLBI Clinical Trials Review study section. Professor Mack received her doctorate from the University of Southern California. Her home is open to needy animals wandering by, and she dabbles in competitive dog obedience in her minimal spare time.

Publications

Kurita K, Henderson VW, Gatz M, St John J, Hodis HN, Karim R, Mack WJ. Association of bilateral oophorectomy with cognitive function in healthy, postmenopausal women. Fertil Steril. 2016 Sep 1; 106(3):749-756. e2. View in: PubMed

Henderson VW, St John JA, Hodis HN, McCleary CA, Stanczyk FZ, Shoupe D, Kono N, Dustin L, Allayee H, Mack WJ. Cognitive effects of estradiol after menopause: A randomized trial of the timing hypothesis. Neurology. 2016 Aug 16; 87(7):699-708. View in: PubMed

Ahmadi N, Ruiz-Garcia J, Hajsadeghi F, Azen S, Mack W, Hodis H, Lerman A. Impaired coronary artery distensibility is an endothelium-dependent process and is associated with vulnerable plaque composition. Clin Physiol Funct Imaging. 2016 Jul; 36(4):261-8. View in: PubMed

Valcour VG, Rubin LH, Obasi MU, Maki PM, Peters MG, Levin S, Crystal HA, Young MA, Mack WJ, Cohen MH, Pierce CB, Adimora AA, Tien PC. Liver Fibrosis Linked to Cognitive Performance in HIV and Hepatitis C. J Acquir Immune Defic Syndr. 2016 Jul 1; 72(3):266-73. View in: PubMed

Love TM, Park SY, Giorgi EE, Mack WJ, Perelson AS, Lee HY. SPMM: estimating infection duration of multivariant HIV-1 infections. Bioinformatics. 2016 May 1; 32(9):1308-15. View in: PubMed

Hornbuckle L, Christina Mehta C, Tien P, Hanna D, Lazar J, Benning L, Cohen M, Mack W, Plankey M, Wingood G. Relationship Between Physical Activity And Cardiovascular Disease Risk In The Women's Interagency HIV Study: 819 Board #135 June 1, 2: 00 PM - 3: 30 PM. Med Sci Sports Exerc. 2016 May; 48(5 Suppl 1):227. View in: PubMed

Rettberg JR, Dang H, Hodis HN, Henderson VW, St John JA, Mack WJ, Brinton RD. Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer's risk metabolic phenotype. Neurobiol Aging. 2016 Apr; 40:155-63. View in: PubMed

Minejima E, Bensman J, She RC, Mack WJ, Tuan Tran M, Ny P, Lou M, Yamaki J, Nieberg P, Ho J, Wong-Beringer A. A Dysregulated Balance of Proinflammatory and Anti-Inflammatory Host Cytokine Response Early During Therapy Predicts Persistence and Mortality in Staphylococcus aureus Bacteremia. Crit Care Med. 2016 Apr; 44(4):671-9. View in: PubMed

Hodis HN, Mack WJ, Henderson VW, Shoupe D, Budoff MJ, Hwang-Levine J, Li Y, Feng M, Dustin L, Kono N, Stanczyk FZ, Selzer RH, Azen SP. Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol. N Engl J Med. 2016 Mar 31; 374(13):1221-31. View in: PubMed

Bowdish ME, Hui DS, Cleveland JD, Mack WJ, Sinha R, Ranjan R, Cohen RG, Baker CJ, Cunningham MJ, Barr ML, Starnes VA. A comparison of aortic valve replacement via an anterior right minithoracotomy with standard sternotomy: a propensity score analysis of 492 patients†. Eur J Cardiothorac Surg. 2016 Feb; 49(2):456-63. View in: PubMed

Kerzerho J, McIlvaine EJ, Anthony P, Mack WJ, Wang CH, Frederick T, Operskalski E, Chen Z, Al-Harthi L, Landay A, Young MA, Tien PC, Augenbraun M, Strickler HD, Akbari O, Golub ET, Sharp GB, Kovacs A. Impact of Hepatitis C Virus on the Circulating Levels of IL-7 in HIV-1 Coinfected Women. J Acquir Immune Defic Syndr. 2016 Feb 1; 71(2):172-80. View in: PubMed

Hajjar I, Wharton W, Mack WJ, Levey AI, Goldstein FC. Racial Disparity in Cognitive and Functional Disability in Hypertension and All-Cause Mortality. Am J Hypertens. 2016 Feb; 29(2):185-93. View in: PubMed

Spencer LY, Christiansen S, Wang CH, Mack WJ, Young M, Strickler HD, Anastos K, Minkoff H, Cohen M, Geenblatt RM, Karim R, Operskalski E, Frederick T, Homans JD, Landay A, Kovacs A. Systemic Immune Activation and HIV Shedding in the Female Genital Tract. J Acquir Immune Defic Syndr. 2016 Feb 1; 71(2):155-62. View in: PubMed

Breton CV, Mack WJ, Yao J, Berhane K, Amadeus M, Lurmann F, Gilliland F, McConnell R, Hodis HN, Künzli N, Avol E. Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults. PLoS One. 2016; 11(3):e0150825. View in: PubMed

Yassine HN, Rawat V, Mack WJ, Quinn JF, Yurko-Mauro K, Bailey-Hall E, Aisen PS, Chui HC, Schneider LS. The effect of APOE genotype on the delivery of DHA to cerebrospinal fluid in Alzheimer's disease. Alzheimers Res Ther. 2016; 8:25. View in: PubMed

Zheng L, Vinters HV, Mack WJ, Weiner MW, Chui HC. Differential effects of ischemic vascular disease and Alzheimer's disease on brain atrophy and cognition. J Cereb Blood Flow Metab. 2016 Jan; 36(1):204-15. View in: PubMed

Park SY, Love TM, Perelson AS, Mack WJ, Lee HY. Molecular clock of HIV-1 envelope genes under early immune selection. Retrovirology. 2016; 13(1):38. View in: PubMed

Hanna DB, Post WS, Deal JA, Hodis HN, Jacobson LP, Mack WJ, Anastos K, Gange SJ, Landay AL, Lazar JM, Palella FJ, Tien PC, Witt MD, Xue X, Young MA, Kaplan RC, Kingsley LA. HIV Infection Is Associated With Progression of Subclinical Carotid Atherosclerosis. Clin Infect Dis. 2015 Aug 15; 61(4):640-50. View in: PubMed

Valcour V, Rubin LH, Tien P, Anastos K, Young M, Mack W, Cohen M, Golub ET, Crystal H, Maki PM. Human immunodeficiency virus (HIV) modulates the associations between insulin resistance and cognition in the current combination antiretroviral therapy (cART) era: a study of the Women's Interagency HIV Study (WIHS). J Neurovirol. 2015 Aug; 21(4):415-21. View in: PubMed

Yin F, Yao J, Sancheti H, Feng T, Melcangi RC, Morgan TE, Finch CE, Pike CJ, Mack WJ, Cadenas E, Brinton RD. The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity. Neurobiol Aging. 2015 Jul; 36(7):2282-95. View in: PubMed

Brinton RD, Yao J, Yin F, Mack WJ, Cadenas E. Perimenopause as a neurological transition state. Nat Rev Endocrinol. 2015 Jul; 11(7):393-405. View in: PubMed

Wecsler JS, Tereffe W, Pedersen RC, Sieffert MR, Mack WJ, Cui H, Russell CA, Woods RR, Viscusi RK, Sener SF, Lang JE. Lymph node status in inflammatory breast cancer. Breast Cancer Res Treat. 2015 May; 151(1):113-20. View in: PubMed

Hodis HN, Mack WJ. Hormone therapy and risk of all-cause mortality in women treated with statins. Menopause. 2015 Apr; 22(4):363-4. View in: PubMed

Hodis HN, Mack WJ, Shoupe D, Azen SP, Stanczyk FZ, Hwang-Levine J, Budoff MJ, Henderson VW. Methods and baseline cardiovascular data from the Early versus Late Intervention Trial with Estradiol testing the menopausal hormone timing hypothesis. Menopause. 2015 Apr; 22(4):391-401. View in: PubMed

Alexy T, Pais E, Wenby RB, Mack WJ, Hodis HN, Kono N, Wang J, Baskurt OK, Fisher TC, Meiselman HJ. Abnormal blood rheology and chronic low grade inflammation: Possible risk factors for accelerated atherosclerosis and coronary artery disease in Lewis negative subjects. Atherosclerosis. 2015 Mar; 239(1):248-51. View in: PubMed

Hajjar I, Hart M, Mack W, Lipsitz LA. Aldosterone, cognitive function, and cerebral hemodynamics in hypertension and antihypertensive therapy. Am J Hypertens. 2015 Mar; 28(3):319-25. View in: PubMed

Karim R, Stanczyk FZ, Brinton RD, Rettberg J, Hodis HN, Mack WJ. Association of endogenous sex hormones with adipokines and ghrelin in postmenopausal women. J Clin Endocrinol Metab. 2015 Feb; 100(2):508-15. View in: PubMed

Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD. Rarity of the Alzheimer Disease-Protective APP A673T Variant in the United States. JAMA Neurol. 2015 Feb 1; 72(2):209-16. View in: PubMed

Yassine HN, Trenchevska O, He H, Borges CR, Nedelkov D, Mack W, Kono N, Koska J, Reaven PD, Nelson RW. Serum amyloid a truncations in type 2 diabetes mellitus. PLoS One. 2015; 10(1):e0115320. View in: PubMed

Jung M, Parrinello CM, Xue X, Mack WJ, Anastos K, Lazar JM, Selzer RH, Shircore AM, Plankey M, Tien P, Cohen M, Gange SJ, Hodis HN, Kaplan RC. Echolucency of the Carotid Artery Intima-Media Complex and Intima-Media Thickness Have Different Cardiovascular Risk Factor Relationships: The Women's Interagency HIV Study. J Am Heart Assoc. 2015; 4(2). View in: PubMed

Baxi SM, Greenblatt RM, Bacchetti P, Jin C, French AL, Keller MJ, Augenbraun MH, Gange SJ, Liu C, Mack WJ, Gandhi M. Nevirapine Concentration in Hair Samples Is a Strong Predictor of Virologic Suppression in a Prospective Cohort of HIV-Infected Patients. PLoS One. 2015; 10(6):e0129100. View in: PubMed

Bauskar A, Mack WJ, Mauris J, Argüeso P, Heur M, Nagel BA, Kolar GR, Gleave ME, Nakamura T, Kinoshita S, Moradian-Oldak J, Panjwani N, Pflugfelder SC, Wilson MR, Fini ME, Jeong S. Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye. PLoS One. 2015; 10(9):e0138958. View in: PubMed

Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA. Effects of multiple genetic Loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov 1; 71(11):1394-404. View in: PubMed

Karim R, Mack WJ, Kono N, Tien PC, Anastos K, Lazar J, Young M, Desai S, Golub ET, Kaplan RC, Hodis HN, Kovacs A. T-Cell Activation, Both Pre- and Post-HAART Levels, Correlates With Carotid Artery Stiffness Over 6. 5 Years Among HIV-Infected Women in the WIHS. J Acquir Immune Defic Syndr. 2014 Nov 1; 67(3):349-56. View in: PubMed

Frasco MA, Karim R, Van Den Berg D, Watanabe RM, Anastos K, Cohen M, Gange SJ, Gustafson DR, Liu C, Tien PC, Mack WJ, Pearce CL. Antiretroviral therapy modifies the genetic effect of known type 2 diabetes-associated risk variants in HIV-infected women. AIDS. 2014 Jul 31; 28(12):1815-23. View in: PubMed

Hodis HN, Mack WJ. Hormone replacement therapy and the association with coronary heart disease and overall mortality: Clinical application of the timing hypothesis. J Steroid Biochem Mol Biol. 2014 Jul; 142:68-75. View in: PubMed

Villeneuve S, Reed BR, Madison CM, Wirth M, Marchant NL, Kriger S, Mack WJ, Sanossian N, DeCarli C, Chui HC, Weiner MW, Jagust WJ. Vascular risk and Aß interact to reduce cortical thickness in AD vulnerable brain regions. Neurology. 2014 Jul 1; 83(1):40-7. View in: PubMed

Hamm-Alvarez SF, Janga SR, Edman MC, Madrigal S, Shah M, Frousiakis SE, Renduchintala K, Zhu J, Bricel S, Silka K, Bach D, Heur M, Christianakis S, Arkfeld DG, Irvine J, Mack WJ, Stohl W. Tear Cathepsin S as a Candidate Biomarker for Sjögren's Syndrome. Arthritis Rheumatol. 2014 Jul; 66(7):1872-81. View in: PubMed

John JA, Henderson VW, Hodis HN, Kono N, McCleary CA, Franke AA, Mack WJ. Associations Between Urine Excretion of Isoflavonoids and Cognition in Postmenopausal Women in the Women's Isoflavone Soy Health Clinical Trial. J Am Geriatr Soc. 2014 Apr; 62(4):629-35. View in: PubMed

Mucowski SJ, Mack WJ, Shoupe D, Kono N, Paulson R, Hodis HN. Effect of prior oophorectomy on changes in bone mineral density and carotid artery intima-media thickness in postmenopausal women. Fertil Steril. 2014 Apr; 101(4):1117-22. View in: PubMed

Villeneuve S, Reed BR, Wirth M, Haase CM, Madison CM, Ayakta N, Mack W, Mungas D, Chui HC, Decarli C, Weiner MW, Jagust WJ. Cortical thickness mediates the effect of ß-amyloid on episodic memory. Neurology. 2014 Mar 4; 82(9):761-7. View in: PubMed

Reed B, Villeneuve S, Mack W, Decarli C, Chui HC, Jagust W. Associations between serum cholesterol levels and cerebral amyloidosis. JAMA Neurol. 2014 Feb 1; 71(2):195-200. View in: PubMed

Frazier DT, Seider T, Bettcher BM, Mack WJ, Jastrzab L, Chao L, Weiner MW, DeCarli C, Reed BR, Mungas D, Chui HC, Kramer JH. The role of carotid intima-media thickness in predicting longitudinal cognitive function in an older adult cohort. Cerebrovasc Dis. 2014; 38(6):441-7. View in: PubMed

Hodis HN, Mack WJ. Response letter to Dr. Timo Strandberg. J Am Geriatr Soc. 2014 Jan; 62(1):206-7. View in: PubMed

Gatto NM, Henderson VW, Hodis HN, St John JA, Lurmann F, Chen JC, Mack WJ. Components of air pollution and cognitive function in middle-aged and older adults in Los Angeles. Neurotoxicology. 2014 Jan; 40:1-7. View in: PubMed

Henderson VW, St John JA, Hodis HN, McCleary CA, Stanczyk FZ, Karim R, Shoupe D, Kono N, Dustin L, Allayee H, Mack WJ. Cognition, mood, and physiological concentrations of sex hormones in the early and late postmenopause. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20290-5. View in: PubMed

Zheng L, Vinters HV, Mack WJ, Zarow C, Ellis WG, Chui HC. Cerebral atherosclerosis is associated with cystic infarcts and microinfarcts but not Alzheimer pathologic changes. Stroke. 2013 Oct; 44(10):2835-41. View in: PubMed

Halliday MR, Pomara N, Sagare AP, Mack WJ, Frangione B, Zlokovic BV. Relationship between cyclophilin a levels and matrix metalloproteinase 9 activity in cerebrospinal fluid of cognitively normal apolipoprotein e4 carriers and blood-brain barrier breakdown. JAMA Neurol. 2013 Sep 1; 70(9):1198-200. View in: PubMed

Quaas AM, Kono N, Mack WJ, Hodis HN, Felix JC, Paulson RJ, Shoupe D. Effect of isoflavone soy protein supplementation on endometrial thickness, hyperplasia, and endometrial cancer risk in postmenopausal women: a randomized controlled trial. Menopause. 2013 Aug; 20(8):840-4. View in: PubMed

Breton CV, Wang X, Mack WJ, Berhane K, Lopez M, Islam TS, Feng M, Lurmann F, McConnell R, Hodis HN, Künzli N, Avol E. Response to letter regarding article, “Childhood air pollutant exposure and carotid artery intima–media thickness in young adults”. Circulation. 2013 Jun 4; 127(22):e659. View in: PubMed

Hodis HN, Mack WJ. The timing hypothesis and hormone replacement therapy: a paradigm shift in the primary prevention of coronary heart disease in women. Part 1: comparison of therapeutic efficacy. J Am Geriatr Soc. 2013 Jun; 61(6):1005-10. View in: PubMed

Karim R, Mack WJ, Stiller T, Operskalski E, Frederick T, Landay A, Young MA, Tien PC, Augenbraun M, Strickler HD, Kovacs A. Association of HIV clinical disease progression with profiles of early immune activation: results from a cluster analysis approach. AIDS. 2013 Jun 1; 27(9):1473-81. View in: PubMed

Hodis HN, Mack WJ. The timing hypothesis and hormone replacement therapy: a paradigm shift in the primary prevention of coronary heart disease in women. Part 2: comparative risks. J Am Geriatr Soc. 2013 Jun; 61(6):1011-8. View in: PubMed

Dratva J, Breton CV, Hodis HN, Mack WJ, Salam MT, Zemp E, Gilliland F, Kuenzli N, Avol E. Birth weight and carotid artery intima-media thickness. J Pediatr. 2013 May; 162(5):906-11. e1-2. View in: PubMed

Karim R, Mack WJ, Kono N, Tien PC, Anastos K, Lazar J, Young M, Cohen M, Golub E, Greenblatt RM, Kaplan RC, Hodis HN. Gonadotropin and sex steroid levels in HIV-infected premenopausal women and their association with subclinical atherosclerosis in HIV-infected and -uninfected women in the women's interagency HIV study (WIHS). J Clin Endocrinol Metab. 2013 Apr; 98(4):E610-8. View in: PubMed

Marchant NL, Reed BR, Sanossian N, Madison CM, Kriger S, Dhada R, Mack WJ, DeCarli C, Weiner MW, Mungas DM, Chui HC, Jagust WJ. The aging brain and cognition: contribution of vascular injury and aß to mild cognitive dysfunction. JAMA Neurol. 2013 Apr; 70(4):488-95. View in: PubMed

Hajjar I, Brown L, Mack WJ, Chui H. Alzheimer pathology and angiotension receptor blockers. JAMA Neurol. 2013 Mar 1; 70(3):414. View in: PubMed

Hajjar I, Hart M, Chen YL, Mack W, Novak V, C Chui H, Lipsitz L. Antihypertensive therapy and cerebral hemodynamics in executive mild cognitive impairment: results of a pilot randomized clinical trial. J Am Geriatr Soc. 2013 Feb; 61(2):194-201. View in: PubMed

Saremi A, Schwenke DC, Buchanan TA, Hodis HN, Mack WJ, Banerji M, Bray GA, Clement SC, Henry RR, Kitabchi AE, Mudaliar S, Ratner RE, Stentz FB, Musi N, Tripathy D, DeFronzo RA, Reaven PD. Pioglitazone slows progression of atherosclerosis in prediabetes independent of changes in cardiovascular risk factors. Arterioscler Thromb Vasc Biol. 2013 Feb; 33(2):393-9. View in: PubMed

Chao LL, Decarli C, Kriger S, Truran D, Zhang Y, Laxamana J, Villeneuve S, Jagust WJ, Sanossian N, Mack WJ, Chui HC, Weiner MW. Associations between white matter hyperintensities and ß amyloid on integrity of projection, association, and limbic fiber tracts measured with diffusion tensor MRI. PLoS One. 2013; 8(6):e65175. View in: PubMed

Hajjar I, Brown L, Mack WJ, Chui H. Impact of Angiotensin receptor blockers on Alzheimer disease neuropathology in a large brain autopsy series. Arch Neurol. 2012 Dec; 69(12):1632-8. View in: PubMed

Cardenas VA, Reed B, Chao LL, Chui H, Sanossian N, Decarli CC, Mack W, Kramer J, Hodis HN, Yan M, Buonocore MH, Carmichael O, Jagust WJ, Weiner MW. Associations among vascular risk factors, carotid atherosclerosis, and cortical volume and thickness in older adults. Stroke. 2012 Nov; 43(11):2865-70. View in: PubMed

Frasco MA, Mack WJ, Van Den Berg D, Aouizerat BE, Anastos K, Cohen M, De Hovitz J, Golub ET, Greenblatt RM, Liu C, Conti DV, Pearce CL. Underlying genetic structure impacts the association between CYP2B6 polymorphisms and response to efavirenz and nevirapine. AIDS. 2012 Oct 23; 26(16):2097-106. View in: PubMed

Breton CV, Wang X, Mack WJ, Berhane K, Lopez M, Islam TS, Feng M, Lurmann F, McConnell R, Hodis HN, Künzli N, Avol E. Childhood air pollutant exposure and carotid artery intima-media thickness in young adults. Circulation. 2012 Sep 25; 126(13):1614-20. View in: PubMed

Villacres MC, Kono N, Mack WJ, Nowicki MJ, Anastos K, Augenbraun M, Liu C, Landay A, Greenblatt RM, Gange SJ, Levine AM. Interleukin 10 Responses Are Associated With Sustained CD4 T-Cell Counts in Treated HIV Infection. J Infect Dis. 2012 Sep; 206(5):780-9. View in: PubMed

Reed BR, Marchant NL, Jagust WJ, Decarli CC, Mack W, Chui HC. Coronary risk correlates with cerebral amyloid deposition. Neurobiol Aging. 2012 Sep; 33(9):1979-87. View in: PubMed

Hajjar I, Mack W, Lipsitz L. Do Angiotensin receptor blockers really hold promise for the improvement of cognitive functioning? -Reply. Arch Intern Med. 2012 Aug 13; 172(15):1191-2. View in: PubMed

Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8. View in: PubMed

Jung S, Zarow C, Mack WJ, Zheng L, Vinters HV, Ellis WG, Lyness SA, Chui HC. Preservation of neurons of the nucleus basalis in subcortical ischemic vascular disease. Arch Neurol. 2012 Jul; 69(7):879-86. View in: PubMed

Ryan J, Stanczyk FZ, Dennerstein L, Mack WJ, Clark MS, Szoeke C, Kildea D, Henderson VW. Hormone levels and cognitive function in postmenopausal midlife women. Neurobiol Aging. 2012 Jul; 33(7):1138-1147. e2. View in: PubMed

Franke AA, Lai JF, Halm BM, Pagano I, Kono N, Mack WJ, Hodis HN. Equol production changes over time in postmenopausal women. J Nutr Biochem. 2012 Jun; 23(6):573-9. View in: PubMed

Gatto NM, Varma R, Torres M, Wong TY, Johnson PL, Segal-Gidan F, Mack WJ. Retinal microvascular abnormalities and cognitive function in latino adults in los angeles. Ophthalmic Epidemiol. 2012 Jun; 19(3):127-36. View in: PubMed

Homans J, Christensen S, Stiller T, Wang CH, Mack W, Anastos K, Minkoff H, Young M, Greenblatt R, Cohen M, Strickler H, Karim R, Spencer LY, Operskalski E, Frederick T, Kovacs A. Permissive and protective factors associated with presence, level, and longitudinal pattern of cervicovaginal HIV shedding. J Acquir Immune Defic Syndr. 2012 May 1; 60(1):99-110. View in: PubMed

Valcour V, Maki P, Bacchetti P, Anastos K, Crystal H, Young M, Mack WJ, Cohen M, Golub ET, Tien PC. Insulin Resistance and Cognition Among HIV-Infected and HIV-Uninfected Adult Women: The Women's Interagency HIV Study. AIDS Res Hum Retroviruses. 2012 May; 28(5):447-53. View in: PubMed

Hajjar I, Hart M, Chen YL, Mack W, Milberg W, Chui H, Lipsitz L. Effect of Antihypertensive Therapy on Cognitive Function in Early Executive Cognitive Impairment: A Double-blind Randomized Clinical Trial. Arch Intern Med. 2012 Mar 12; 172(5):442-4. View in: PubMed

Zheng L, Mack WJ, Chui HC, Heflin L, Mungas D, Reed B, Decarli C, Weiner MW, Kramer JH. Coronary artery disease is associated with cognitive decline independent of changes on magnetic resonance imaging in cognitively normal elderly adults. J Am Geriatr Soc. 2012 Mar; 60(3):499-504. View in: PubMed

Ryan J, Stanczyk FZ, Dennerstein L, Mack WJ, Clark MS, Szoeke C, Kildea D, Henderson VW. Hormone levels and cognitive function in postmenopausal midlife women. Neurobiol Aging. 2012 Mar; 33(3):617. e11-22. View in: PubMed

Schwartz RM, Mansoor A, Wilson TE, Anastos K, Everson-Rose SA, Golub ET, Goparaju L, Hessol NA, Mack WJ, Lazar J. Chronic depressive symptoms and Framingham coronary risk in HIV-infected and HIV-uninfected women. AIDS Care. 2012 Mar; 24(3):394-403. View in: PubMed

Zheng L, Teng EL, Varma R, Mack WJ, Mungas D, Lu PH, Chui HC. Chinese-language montreal cognitive assessment for cantonese or mandarin speakers: age, education, and gender effects. Int J Alzheimers Dis. 2012; 2012:204623. View in: PubMed

Zhao L, Morgan TE, Mao Z, Lin S, Cadenas E, Finch CE, Pike CJ, Mack WJ, Brinton RD. Continuous versus Cyclic Progesterone Exposure Differentially Regulates Hippocampal Gene Expression and Functional Profiles. PLoS One. 2012; 7(2):e31267. View in: PubMed

Chui HC, Zheng L, Reed BR, Vinters HV, Mack WJ. Vascular risk factors and Alzheimer's disease: are these risk factors for plaques and tangles or for concomitant vascular pathology that increases the likelihood of dementia? An evidence-based review. Alzheimers Res Ther. 2012; 4(1):1. View in: PubMed

Karim R, Dell RM, Greene DF, Mack WJ, Gallagher JC, Hodis HN. Hip fracture in postmenopausal women after cessation of hormone therapy: results from a prospective study in a large health management organization. Menopause. 2011 Nov; 18(11):1172-7. View in: PubMed

Hodis HN, Mack WJ, Kono N, Azen SP, Shoupe D, Hwang-Levine J, Petitti D, Whitfield-Maxwell L, Yan M, Franke AA, Selzer RH. Isoflavone soy protein supplementation and atherosclerosis progression in healthy postmenopausal women: a randomized controlled trial. Stroke. 2011 Nov; 42(11):3168-75. View in: PubMed

Crystal HA, Weedon J, Holman S, Manly J, Valcour V, Cohen M, Anastos K, Liu C, Mack WJ, Golub E, Lazar J, Ho A, Kreek MJ, Kaplan RC. Associations of cardiovascular variables and HAART with cognition in middle-aged HIV-infected and uninfected women. J Neurovirol. 2011 Oct; 17(5):469-76. View in: PubMed

Baker JV, Henry WK, Patel P, Bush TJ, Conley LJ, Mack WJ, Overton ET, Budoff M, Hammer J, Carpenter CC, Hodis HN, Brooks JT. Progression of carotid intima-media thickness in a contemporary human immunodeficiency virus cohort. Clin Infect Dis. 2011 Oct; 53(8):826-35. View in: PubMed

Choudhury F, Bernstein L, Hodis HN, Stanczyk FZ, Mack WJ. Physical activity and sex hormone levels in estradiol- and placebo-treated postmenopausal women. Menopause. 2011 Oct; 18(10):1079-86. View in: PubMed

Breton CV, Wang X, Mack WJ, Berhane K, Lopez M, Islam TS, Feng M, Hodis HN, Künzli N, Avol E. Carotid artery intima-media thickness in college students: race/ethnicity matters. Atherosclerosis. 2011 Aug; 217(2):441-6. View in: PubMed

Vigen CL, Mack WJ, Keefe RS, Sano M, Sultzer DL, Stroup TS, Dagerman KS, Hsiao JK, Lebowitz BD, Lyketsos CG, Tariot PN, Zheng L, Schneider LS. Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-AD. Am J Psychiatry. 2011 Aug; 168(8):831-9. View in: PubMed

Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41. View in: PubMed

Wahl SM, Redford M, Christensen S, Mack W, Cohn J, Janoff EN, Mestecky J, Jenson HB, Navazesh M, Cohen M, Reichelderfer P, Kovacs A. Systemic and mucosal differences in HIV burden, immune, and therapeutic responses. J Acquir Immune Defic Syndr. 2011 Apr 15; 56(5):401-11. View in: PubMed

DeFronzo RA, Tripathy D, Schwenke DC, Banerji M, Bray GA, Buchanan TA, Clement SC, Henry RR, Hodis HN, Kitabchi AE, Mack WJ, Mudaliar S, Ratner RE, Williams K, Stentz FB, Musi N, Reaven PD. Pioglitazone for diabetes prevention in impaired glucose tolerance. N Engl J Med. 2011 Mar 24; 364(12):1104-15. View in: PubMed

Ryan J, Stanczyk FZ, Dennerstein L, Mack WJ, Clark MS, Szoeke C, Henderson VW. Executive functions in recently postmenopausal women: absence of strong association with serum gonadal steroids. Brain Res. 2011 Mar 16; 1379:199-205. View in: PubMed

Hodis HN, Mack WJ. A "window of opportunity:" The reduction of coronary heart disease and total mortality with menopausal therapies is age- and time-dependent. Brain Res. 2011 Mar 16; 1379:244-52. View in: PubMed

Brommelhoff JA, Spann BM, Go JL, Mack WJ, Gatz M. Striatal Hypodensities, Not White Matter Hypodensities on CT, Are Associated with Late-Onset Depression in Alzheimer's Disease. J Aging Res. 2011; 2011:187219. View in: PubMed

Seaberg EC, Benning L, Sharrett AR, Lazar JM, Hodis HN, Mack WJ, Siedner MJ, Phair JP, Kingsley LA, Kaplan RC. Association between human immunodeficiency virus infection and stiffness of the common carotid artery. Stroke. 2010 Oct; 41(10):2163-70. View in: PubMed

Karim R, Stanczyk FZ, Hodis HN, Cushman M, Lobo RA, Hwang J, Mack WJ. Associations between markers of inflammation and physiological and pharmacological levels of circulating sex hormones in postmenopausal women. Menopause. 2010 Jul; 17(4):785-90. View in: PubMed

Franke AA, Hebshi SM, Pagano I, Kono N, Mack WJ, Hodis HN. Urine accurately reflects circulating isoflavonoids and ascertains compliance during soy intervention. Cancer Epidemiol Biomarkers Prev. 2010 Jul; 19(7):1775-83. View in: PubMed

Lavretsky H, Zheng L, Weiner MW, Mungas D, Reed B, Kramer JH, Jagust W, Chui H, Mack WJ. Association of depressed mood and mortality in older adults with and without cognitive impairment in a prospective naturalistic study. Am J Psychiatry. 2010 May; 167(5):589-97. View in: PubMed

Segal-Gidan F, Varma R, Salazar X, Mack WJ. Factors influencing driving status in an older Latino population. J Aging Health. 2010 Apr; 22(3):332-47. View in: PubMed

Kovacs A, Karim R, Mack WJ, Xu J, Chen Z, Operskalski E, Frederick T, Landay A, Voris J, Spencer LS, Young MA, Tien PC, Augenbraun M, Strickler HD, Al-Harthi L. Activation of CD8 T cells predicts progression of HIV infection in women coinfected with hepatitis C virus. J Infect Dis. 2010 Mar 15; 201(6):823-34. View in: PubMed

Mueller SG, Mack WJ, Mungas D, Kramer JH, Cardenas-Nicolson V, Lavretsky H, Greene M, Schuff N, Chui HC, Weiner MW. Influences of lobar gray matter and white matter lesion load on cognition and mood. Psychiatry Res. 2010 Feb 28; 181(2):90-6. View in: PubMed

Künzli N, Jerrett M, Garcia-Esteban R, Basagaña X, Beckermann B, Gilliland F, Medina M, Peters J, Hodis HN, Mack WJ. Ambient air pollution and the progression of atherosclerosis in adults. PLoS One. 2010; 5(2):e9096. View in: PubMed

Clark LJ, Gatz M, Zheng L, Chen YL, McCleary C, Mack WJ. Longitudinal verbal fluency in normal aging, preclinical, and prevalent Alzheimer's disease. Am J Alzheimers Dis Other Demen. 2009 Dec-2010 Jan; 24(6):461-8. View in: PubMed

Karim R, Mack WJ, Hodis HN, Roy S, Stanczyk FZ. Influence of age and obesity on serum estradiol, estrone, and sex hormone binding globulin concentrations following oral estrogen administration in postmenopausal women. J Clin Endocrinol Metab. 2009 Nov; 94(11):4136-43. View in: PubMed

Frederick T, Burian P, Terrault N, Cohen M, Augenbraun M, Young M, Seaberg E, Justman J, Levine AM, Mack WJ, Kovacs A. Factors associated with prevalent hepatitis C infection among HIV-infected women with no reported history of injection drug use: the Women's Interagency HIV Study (WIHS). AIDS Patient Care STDS. 2009 Nov; 23(11):915-23. View in: PubMed

Tien PC, Schneider MF, Cole SR, Cohen MH, Glesby MJ, Lazar J, Young M, Mack W, Hodis HN, Kaplan RC. Association of hepatitis C virus and HIV infection with subclinical atherosclerosis in the women's interagency HIV study. AIDS. 2009 Aug 24; 23(13):1781-4. View in: PubMed

Zheng L, Mack WJ, Dagerman KS, Hsiao JK, Lebowitz BD, Lyketsos CG, Stroup TS, Sultzer DL, Tariot PN, Vigen C, Schneider LS. Metabolic changes associated with second-generation antipsychotic use in Alzheimer's disease patients: the CATIE-AD study. Am J Psychiatry. 2009 May; 166(5):583-90. View in: PubMed

Gatto NM, Henderson VW, St John JA, McCleary C, Detrano R, Hodis HN, Mack WJ. Subclinical atherosclerosis is weakly associated with lower cognitive function in healthy hyperhomocysteinemic adults without clinical cardiovascular disease. Int J Geriatr Psychiatry. 2009 Apr; 24(4):390-9. View in: PubMed

Hodis HN, Mack WJ, Dustin L, Mahrer PR, Azen SP, Detrano R, Selhub J, Alaupovic P, Liu CR, Liu CH, Hwang J, Wilcox AG, Selzer RH. High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomized controlled trial. Stroke. 2009 Mar; 40(3):730-6. View in: PubMed

Kapetanovic S, Christensen S, Karim R, Lin F, Mack WJ, Operskalski E, Frederick T, Spencer L, Stek A, Kramer F, Kovacs A. Correlates of perinatal depression in HIV-infected women. AIDS Patient Care STDS. 2009 Feb; 23(2):101-8. View in: PubMed

St John JA, Henderson VW, Gatto NM, McCleary CA, Spencer CA, Hodis HN, Mack WJ. Mildly elevated TSH and cognition in middle-aged and older adults. Thyroid. 2009 Feb; 19(2):111-7. View in: PubMed

Lavretsky H, Zheng L, Weiner MW, Mungas D, Reed B, Kramer JH, Jagust W, Chui H, Mack WJ. The MRI brain correlates of depressed mood, anhedonia, apathy, and anergia in older adults with and without cognitive impairment or dementia. Int J Geriatr Psychiatry. 2008 Oct; 23(10):1040-50. View in: PubMed

Karim R, Hodis HN, Detrano R, Liu CR, Liu CH, Mack WJ. Relation of Framingham risk score to subclinical atherosclerosis evaluated across three arterial sites. Am J Cardiol. 2008 Oct 1; 102(7):825-30. View in: PubMed

Gatto NM, Henderson VW, St John JA, McCleary C, Hodis HN, Mack WJ. Metabolic syndrome and cognitive function in healthy middle-aged and older adults without diabetes. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2008 Sep; 15(5):627-41. View in: PubMed

Hodis HN, Mack WJ. Postmenopausal hormone therapy and cardiovascular disease in perspective. Clin Obstet Gynecol. 2008 Sep; 51(3):564-80. View in: PubMed

Kovacs A, Al-Harthi L, Christensen S, Mack W, Cohen M, Landay A. CD8(+) T cell activation in women coinfected with human immunodeficiency virus type 1 and hepatitis C virus. J Infect Dis. 2008 May 15; 197(10):1402-7. View in: PubMed

Brinton RD, Thompson RF, Foy MR, Baudry M, Wang J, Finch CE, Morgan TE, Pike CJ, Mack WJ, Stanczyk FZ, Nilsen J. Progesterone receptors: form and function in brain. Front Neuroendocrinol. 2008 May; 29(2):313-39. View in: PubMed

Hodis HN, St John JA, Xiang M, Cushman M, Lobo RA, Mack WJ. Inflammatory markers and progression of subclinical atherosclerosis in healthy postmenopausal women (from the Estrogen in the Prevention of Atherosclerosis Trial). Am J Cardiol. 2008 Apr 15; 101(8):1131-3. View in: PubMed

Operskalski EA, Mack WJ, Strickler HD, French AL, Augenbraun M, Tien PC, Villacres MC, Spencer LY, Degiacomo M, Kovacs A. Factors associated with hepatitis C viremia in a large cohort of HIV-infected and -uninfected women. J Clin Virol. 2008 Apr; 41(4):255-63. View in: PubMed

Gatto NM, Hodis HN, Liu CR, Liu CH, Mack WJ. Brachial artery vasoreactivity is associated with cross-sectional and longitudinal anatomical measures of atherosclerosis in postmenopausal women with coronary artery disease. Atherosclerosis. 2008 Feb; 196(2):674-81. View in: PubMed

Nowicki MJ, Vigen C, Mack WJ, Seaberg E, Landay A, Anastos K, Young M, Minkoff H, Greenblatt R, Levine AM. Association of cells with natural killer (NK) and NKT immunophenotype with incident cancers in HIV-infected women. AIDS Res Hum Retroviruses. 2008 Feb; 24(2):163-8. View in: PubMed

Jagust WJ, Zheng L, Harvey DJ, Mack WJ, Vinters HV, Weiner MW, Ellis WG, Zarow C, Mungas D, Reed BR, Kramer JH, Schuff N, DeCarli C, Chui HC. Neuropathological basis of magnetic resonance images in aging and dementia. Ann Neurol. 2008 Jan; 63(1):72-80. View in: PubMed

Karim R, Hodis HN, Stanczyk FZ, Lobo RA, Mack WJ. Relationship between serum levels of sex hormones and progression of subclinical atherosclerosis in postmenopausal women. J Clin Endocrinol Metab. 2008 Jan; 93(1):131-8. View in: PubMed

Khalsa A, Karim R, Mack WJ, Minkoff H, Cohen M, Young M, Anastos K, Tien PC, Seaberg E, Levine AM. Correlates of prevalent hypertension in a large cohort of HIV-infected women: Women's Interagency HIV Study. AIDS. 2007 Nov 30; 21(18):2539-41. View in: PubMed

Kaplan RC, Kingsley LA, Sharrett AR, Li X, Lazar J, Tien PC, Mack WJ, Cohen MH, Jacobson L, Gange SJ. Ten-year predicted coronary heart disease risk in HIV-infected men and women. Clin Infect Dis. 2007 Oct 15; 45(8):1074-81. View in: PubMed

Hodis HN, Mack WJ. Estrogen therapy and coronary-artery calcification. N Engl J Med. 2007 Sep 20; 357(12):1252-3; author reply 1254. View in: PubMed

Hodis HN, Mack WJ. Postmenopausal hormone therapy in clinical perspective. Menopause. 2007 Sep-Oct; 14(5):944-57. View in: PubMed

Laskus T, Wilkinson J, Karim R, Mack W, Radkowski M, deGiacomo M, Nasseri J, Chen Z, Xu J, Kovacs A. Hepatitis C virus quasispecies in HIV-infected women: role of injecting drug use and highly active antiretroviral therapy (HAART). Hepatology. 2007 Aug; 46(2):359-70. View in: PubMed

Henderson SO, Simma-Chiang V, Lee C, Calder K, Mack WJ. Asthma: Effect of genotype on Response to Therapy in the Emergency Department. West J Emerg Med. 2007 Aug; 8(3):73-7. View in: PubMed

Nowicki MJ, Karim R, Mack WJ, Minkoff H, Anastos K, Cohen M, Greenblatt RM, Young MA, Gange SJ, Levine AM. Correlates of CD4+ and CD8+ lymphocyte counts in high-risk immunodeficiency virus (HIV)-seronegative women enrolled in the women's interagency HIV study (WIHS). Hum Immunol. 2007 May; 68(5):342-9. View in: PubMed

Zheng L, Hodis HN, Buchanan TA, Li Y, Mack WJ. Effect of antihypertensive therapy on progression of carotid intima-media thickness in patients with type 2 diabetes mellitus. Am J Cardiol. 2007 Apr 1; 99(7):956-60. View in: PubMed

Mack WJ, Dhungana B, Dowsett SA, Keech CA, Feng M, Li Y, Hodis HN. Carotid artery intima-media thickness after raloxifene treatment. J Womens Health (Larchmt). 2007 Apr; 16(3):370-8. View in: PubMed

Steiner AZ, Xiang M, Mack WJ, Shoupe D, Felix JC, Lobo RA, Hodis HN. Unopposed estradiol therapy in postmenopausal women: results from two randomized trials. Obstet Gynecol. 2007 Mar; 109(3):581-7. View in: PubMed

Laskus T, Operskalski EA, Radkowski M, Wilkinson J, Mack WJ, deGiacomo M, Al-Harthi L, Chen Z, Xu J, Kovacs A. Negative-strand hepatitis C virus (HCV) RNA in peripheral blood mononuclear cells from anti-HCV-positive/HIV-infected women. J Infect Dis. 2007 Jan 1; 195(1):124-33. View in: PubMed

El-Shahawy M, Noureddin M, Abdullah H, Mack WJ, Calverley DC. Platelet FcgammaRIIA receptor surface expression is increased in patients with ESRD and is associated with atherosclerotic cardiovascular events. Am J Kidney Dis. 2007 Jan; 49(1):127-34. View in: PubMed

Chui HC, Zarow C, Mack WJ, Ellis WG, Zheng L, Jagust WJ, Mungas D, Reed BR, Kramer JH, Decarli CC, Weiner MW, Vinters HV. Cognitive impact of subcortical vascular and Alzheimer's disease pathology. Ann Neurol. 2006 Dec; 60(6):677-87. View in: PubMed

Lin TC, Tintut Y, Lyman A, Mack W, Demer LL, Hsiai TK. Mechanical response of a calcified plaque model to fluid shear force. Ann Biomed Eng. 2006 Oct; 34(10):1535-41. View in: PubMed

Li X, Chu H, Gallant JE, Hoover DR, Mack WJ, Chmiel JS, Muñoz A. Bimodal virological response to antiretroviral therapy for HIV infection: an application using a mixture model with left censoring. J Epidemiol Community Health. 2006 Sep; 60(9):811-8. View in: PubMed

Levine AM, Vigen C, Gravink J, Mack W, Watts CH, Liebman HA. Progressive prothrombotic state in women with advancing HIV disease. J Acquir Immune Defic Syndr. 2006 Aug 15; 42(5):572-7. View in: PubMed

Hodis HN, Mack WJ, Zheng L, Li Y, Torres M, Sevilla D, Stewart Y, Hollen B, Garcia K, Alaupovic P, Buchanan TA. Effect of peroxisome proliferator-activated receptor gamma agonist treatment on subclinical atherosclerosis in patients with insulin-requiring type 2 diabetes. Diabetes Care. 2006 Jul; 29(7):1545-53. View in: PubMed

Levine AM, Karim R, Mack W, Gravink DJ, Anastos K, Young M, Cohen M, Newman M, Augenbraun M, Gange S, Watts DH. Neutropenia in human immunodeficiency virus infection: data from the women's interagency HIV study. Arch Intern Med. 2006 Feb 27; 166(4):405-10. View in: PubMed

Andel R, Vigen C, Mack WJ, Clark LJ, Gatz M. The effect of education and occupational complexity on rate of cognitive decline in Alzheimer's patients. J Int Neuropsychol Soc. 2006 Jan; 12(1):147-52. View in: PubMed

Steiner AZ, Hodis HN, Lobo RA, Shoupe D, Xiang M, Mack WJ. Postmenopausal oral estrogen therapy and blood pressure in normotensive and hypertensive subjects: the Estrogen in the Prevention of Atherosclerosis Trial. Menopause. 2005 Nov-Dec; 12(6):728-33. View in: PubMed

Meeske KA, Siegel SE, Globe DR, Mack WJ, Bernstein L. Prevalence and correlates of fatigue in long-term survivors of childhood leukemia. J Clin Oncol. 2005 Aug 20; 23(24):5501-10. View in: PubMed

Hwang J, Mack WJ, Xiang M, Sevanian A, Lobo RA, Hodis HN. Long-term effect of estrogen replacement on plasma nitric oxide levels: results from the estrogen in the prevention of atherosclerosis trial (EPAT). Atherosclerosis. 2005 Aug; 181(2):375-80. View in: PubMed

Karim R, Mack WJ, Lobo RA, Hwang J, Liu CR, Liu CH, Sevanian A, Hodis HN. Determinants of the effect of estrogen on the progression of subclinical atherosclerosis: Estrogen in the Prevention of Atherosclerosis Trial. Menopause. 2005 Jul-Aug; 12(4):366-73. View in: PubMed

Mack WJ, Teng E, Zheng L, Paz S, Chui H, Varma R. Category fluency in a latino sample: associations with age, education, gender, and language. J Clin Exp Neuropsychol. 2005 Jul; 27(5):591-8. View in: PubMed

Vigen C, Hodis HN, Selzer RH, Mahrer PR, Mack WJ. Relation of progression of coronary artery atherosclerosis to risk of cardiovascular events (from the Monitored Atherosclerosis Regression Study). Am J Cardiol. 2005 Jun 1; 95(11):1277-82. View in: PubMed

Künzli N, Jerrett M, Mack WJ, Beckerman B, LaBree L, Gilliland F, Thomas D, Peters J, Hodis HN. Ambient air pollution and atherosclerosis in Los Angeles. Environ Health Perspect. 2005 Feb; 113(2):201-6. View in: PubMed

Lord SJ, Mack WJ, Van Den Berg D, Pike MC, Ingles SA, Haiman CA, Wang W, Parisky YR, Hodis HN, Ursin G. Polymorphisms in genes involved in estrogen and progesterone metabolism and mammographic density changes in women randomized to postmenopausal hormone therapy: results from a pilot study. Breast Cancer Res. 2005; 7(3):R336-44. View in: PubMed

Henderson SO, Haiman CA, Mack W. Multiple Polymorphisms in the renin- angiotensin-aldosterone system (ACE, CYP11B2, AGTR1) and their contribution to hypertension in African Americans and Latinos in the multiethnic cohort. Am J Med Sci. 2004 Nov; 328(5):266-73. View in: PubMed

Krantz JS, Mack WJ, Hodis HN, Liu CR, Liu CH, Kaufman FR. Early onset of subclinical atherosclerosis in young persons with type 1 diabetes. J Pediatr. 2004 Oct; 145(4):452-7. View in: PubMed

Mack WJ, Slater CC, Xiang M, Shoupe D, Lobo RA, Hodis HN. Elevated subclinical atherosclerosis associated with oophorectomy is related to time since menopause rather than type of menopause. Fertil Steril. 2004 Aug; 82(2):391-7. View in: PubMed

Zheng L, Buchanan TA, Hodis HN, Li Y, Torres M, Mack WJ. Time from diagnosis of type 2 diabetes to initiation of insulin therapy is related to carotid artery intima-media thickness. Atherosclerosis. 2003 Oct; 170(2):293-9. View in: PubMed

Mack WJ, Preston-Martin S, Dal Maso L, Galanti R, Xiang M, Franceschi S, Hallquist A, Jin F, Kolonel L, La Vecchia C, Levi F, Linos A, Lund E, McTiernan A, Mabuchi K, Negri E, Wingren G, Ron E. A pooled analysis of case-control studies of thyroid cancer: cigarette smoking and consumption of alcohol, coffee, and tea. Cancer Causes Control. 2003 Oct; 14(8):773-85. View in: PubMed

Hodis HN, Mack WJ, Azen SP, Lobo RA, Shoupe D, Mahrer PR, Faxon DP, Cashin-Hemphill L, Sanmarco ME, French WJ, Shook TL, Gaarder TD, Mehra AO, Rabbani R, Sevanian A, Shil AB, Torres M, Vogelbach KH, Selzer RH. Hormone therapy and the progression of coronary-artery atherosclerosis in postmenopausal women. N Engl J Med. 2003 Aug 7; 349(6):535-45. View in: PubMed

Mack WJ, Islam T, Lee Z, Selzer RH, Hodis HN. Environmental tobacco smoke and carotid arterial stiffness. Prev Med. 2003 Aug; 37(2):148-54. View in: PubMed

Hodis HN, Mack WJ, Lobo RA. Randomized controlled trial evidence that estrogen replacement therapy reduces the progression of subclinical atherosclerosis in healthy postmenopausal women without preexisting cardiovascular disease. Circulation. 2003 Jul 8; 108(1):e5; author reply e5. View in: PubMed

Mack WJ, Hameed AB, Xiang M, Roy S, Slater CC, Stanczyk FZ, Lobo RA, Liu CR, Liu CH, Hodis HN. Does elevated body mass modify the influence of postmenopausal estrogen replacement on atherosclerosis progression: results from the estrogen in the prevention of atherosclerosis trial. Atherosclerosis. 2003 May; 168(1):91-8. View in: PubMed

Hodis HN, Mack WJ, Lobo R. What is the cardioprotective role of hormone replacement therapy? Curr Atheroscler Rep. 2003 Jan; 5(1):56-66. View in: PubMed

Hodis HN, Mack WJ, LaBree L, Mahrer PR, Sevanian A, Liu CR, Liu CH, Hwang J, Selzer RH, Azen SP. Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis: the Vitamin E Atherosclerosis Prevention Study (VEAPS). Circulation. 2002 Sep 17; 106(12):1453-9. View in: PubMed

Mack WJ, Preston-Martin S, Bernstein L, Qian D. Lifestyle and other risk factors for thyroid cancer in Los Angeles County females. Ann Epidemiol. 2002 Aug; 12(6):395-401. View in: PubMed

Sobel BE, Neimane D, Mack WJ, Hodis HN, Buchanan TA. The ratio of plasminogen activator inhibitor type-1 activity to the concentration of plasminogen activator inhibitor type-1 protein in diabetes: adding insult to injury. Coron Artery Dis. 2002 Aug; 13(5):275-81. View in: PubMed

Hodis HN, Mack WJ, Lobo R. Antiatherosclerosis interventions in women. Am J Cardiol. 2002 Jul 3; 90(1A):17F-21F. View in: PubMed

Hodis HN, Mack WJ. Atherosclerosis imaging methods: assessing cardiovascular disease and evaluating the role of estrogen in the prevention of atherosclerosis. Am J Cardiol. 2002 Jun 20; 89(12A):19E-27E; discussion 27E. View in: PubMed

Hodis HN, Mack WJ, Lobo R. Postmenopausal hormone replacement therapy as antiatherosclerotic therapy. Curr Atheroscler Rep. 2002 Jan; 4(1):52-8. View in: PubMed

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