Faculty

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Yuri S. Genyk, MD
Professor of Clinical Surgery
Surgery
HCC 200 Health Sciences Campus Los Angeles
+1 323 442 5908

Overview

Dr. Genyk is an assistant professor of surgery at the USC School of Medicine and the Division of Hepatobiliary/Pancreatic and Abdominal Organ Transplant Surgery. Additionally, he is an attending surgeon at Children’s Hospital of Los Angeles (CHLA). Dr. Genyk graduated with honors from Ivano-Frankivk’s Medical Institute in Ukraine. He received his postgraduate medical and research training at Baylor University Medical Center in Dallas, Texas, University of Alabama at Birmingham Medical Center and Mount Sinai Medical Center in New York City. He is an expert in living-related donor liver transplantation, adult and pediatric liver transplantation, laparoscopic donor nephrectomy for kidney transplantation, pancreas transplantation as well as non-transplant hepatobiliary and pancreatic surgery. Shortly after Dr. Genyk joined the USC faculty, the USC Liver Transplant Team pioneered living-related donor liver transplantation at CHLA and Keck Hospital of USC. Dr. Genyk is board certified in general surgery and ASTS certified in transplantation surgery. He is associate director of Abdominal Organ Transplant and surgical director of Living Donor Liver Transplant Program at USCUH, as well as surgical director of Pediatric Liver/Intestinal Transplant Program at CHLA. His research interests include innovations in live donor liver transplantation, new approaches to surgical treatment of extensive tumors of liver and pancreas, minimally invasive surgery for hepatobiliary and pancreatic diseases, liver regeneration and immunological tolerance in transplantation.

Publications

Alexopoulos SP, Nekrasov V, Cao S, Groshen S, Kaur N, Genyk YS, Matsuoka L. Effects of Recipient Size and Allograft Type on Pediatric Liver Transplantation for Biliary Atresia. Liver Transpl. 2016 Nov 10. View in: PubMed

Genyk Y. Liver Condition and Resection: In reply to Toro and colleagues. J Am Coll Surg. 2016 Oct; 223(4):678. View in: PubMed

Genyk Y. Secondary Treatment of Local Bleeding in Patients Undergoing Hepatic Resection: In reply to Sugimachi. J Am Coll Surg. 2016 Aug; 223(2):419-20. View in: PubMed

Genyk Y. Secondary Treatment of Local Bleeding in Patients Undergoing Hepatic Resection: In reply to Sugimachi. J Am Coll Surg. 2016 Aug; 223(2):419-20. View in: PubMed

Nadim MK, Durand F, Kellum JA, Levitsky J, O'Leary JG, Karvellas CJ, Bajaj JS, Davenport A, Jalan R, Angeli P, Caldwell SH, Fernández J, Francoz C, Garcia-Tsao G, Ginès P, Ison MG, Kramer DJ, Mehta RL, Moreau R, Mulligan D, Olson JC, Pomfret EA, Senzolo M, Steadman RH, Subramanian RM, Vincent JL, Genyk YS. Management of the critically ill patient with cirrhosis: A multidisciplinary perspective. J Hepatol. 2016 Mar; 64(3):717-35. View in: PubMed

Genyk Y, Kato T, Pomposelli JJ, Wright JK, Sher LS, Tetens V, Chapman WC. Fibrin Sealant Patch (TachoSil) vs Oxidized Regenerated Cellulose Patch (Surgicel Original) for the Secondary Treatment of Local Bleeding in Patients Undergoing Hepatic Resection: A Randomized Controlled Trial. J Am Coll Surg. 2016 Mar; 222(3):261-8. View in: PubMed

Yang CH, Zhou S, Alexopoulos S, Wang L, Baron HI, Genyk Y, Kerkar N. Orthotopic liver transplant for multifocal lymphangioendotheliomatosis with thrombocytopenia. Pediatr Transplant. 2016 Feb 25. View in: PubMed

Parikh A, Washburn KW, Matsuoka L, Pandit U, Kim JE, Almeda J, Mora-Esteves C, Halff G, Genyk Y, Holland B, Wilson DJ, Sher L, Koneru B. A multicenter study of 30 days complications after deceased donor liver transplantation in the model for end-stage liver disease score era. Liver Transpl. 2015 Sep; 21(9):1160-8. View in: PubMed

Chan R, Mascarenhas L, Boles RG, Kerkar N, Genyk Y, Venkatramani R. Hepatoblastoma in a patient with methylmalonic aciduria. Am J Med Genet A. 2015 Mar; 167(3):635-8. View in: PubMed

Venkatramani R, Stein JE, Sapra A, Genyk Y, Jhaveri V, Malogolowkin M, Mascarenhas L. Effect of neoadjuvant chemotherapy on resectability of stage III and IV hepatoblastoma. Br J Surg. 2015 Jan; 102(1):108-13. View in: PubMed

Alhosh R, Genyk Y, Alexopoulos S, Thomas D, Zhou S, Yanni G, Kerkar N. Hepatopulmonary syndrome associated with nodular regenerative hyperplasia after liver transplantation in a child. Pediatr Transplant. 2014 Aug; 18(5):E157-60. View in: PubMed

Nadim MK, Annanthapanyasut W, Matsuoka L, Appachu K, Boyajian M, Ji L, Sedra A, Genyk YS. Intraoperative hemodialysis during liver transplantation: A decade of experience. Liver Transpl. 2014 Jul; 20(7):756-64. View in: PubMed

Matsuoka L, Alexopoulos S, Petrovik L, Chan L, Genyk Y, Selby R. Trisectionectomy for cholangiocarcinoma: is it worth it? Am Surg. 2014 Jun; 80(6):544-8. View in: PubMed

Derek E, Matsuoka L, Alexopoulos S, Fedenko A, Genyk Y, Selby R. Combined surgical resection and radiofrequency ablation as treatment for metastatic ocular melanoma. Surg Today. 2013 Apr; 43(4):367-71. View in: PubMed

Alexopoulos S, Matsuoka L, Cho Y, Thomas E, Sheikh M, Stapfer M, Dhanireddy K, Sher L, Selby R, Genyk Y. Outcomes after liver transplantation in patients achieving a model for end-stage liver disease score of 40 or higher. Transplantation. 2013 Feb 15; 95(3):507-12. View in: PubMed

Nadim MK, Davis CL, Sung R, Kellum JA, Genyk YS. Simultaneous liver-kidney transplantation: a survey of US transplant centers. Am J Transplant. 2012 Nov; 12(11):3119-27. View in: PubMed

Nadim MK, Sung RS, Davis CL, Andreoni KA, Biggins SW, Danovitch GM, Feng S, Friedewald JJ, Hong JC, Kellum JA, Kim WR, Lake JR, Melton LB, Pomfret EA, Saab S, Genyk YS. Simultaneous liver-kidney transplantation summit: current state and future directions. Am J Transplant. 2012 Nov; 12(11):2901-8. View in: PubMed

Nadim MK, Genyk YS, Tokin C, Fieber J, Ananthapanyasut W, Ye W, Selby R. Impact of the etiology of acute kidney injury on outcomes following liver transplantation: acute tubular necrosis versus hepatorenal syndrome. Liver Transpl. 2012 May; 18(5):539-48. View in: PubMed

Pierce JR, Hunter CJ, Naik-Mathuria B, Stanley P, Ford HR, Genyk Y, Shaul DB, Panossian A, Anselmo DM. Colonic venous malformation and portal hypertension: association, management, and review of the literature. Pediatr Surg Int. 2012 Apr; 28(4):435-8. View in: PubMed

Matsuoka L, Selby R, Genyk Y. The surgical management of pancreatic cancer. Gastroenterol Clin North Am. 2012 Mar; 41(1):211-21. View in: PubMed

Nadim MK, Kellum JA, Davenport A, Wong F, Davis C, Pannu N, Tolwani A, Bellomo R, Genyk YS. Hepatorenal syndrome: the 8th international consensus conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care. 2012; 16(1):R23. View in: PubMed

Davenport A, Ahmad J, Al-Khafaji A, Kellum JA, Genyk YS, Nadim MK. Medical management of hepatorenal syndrome. Nephrol Dial Transplant. 2012 Jan; 27(1):34-41. View in: PubMed

Wong F, Nadim MK, Kellum JA, Salerno F, Bellomo R, Gerbes A, Angeli P, Moreau R, Davenport A, Jalan R, Ronco C, Genyk Y, Arroyo V. Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis. Gut. 2011 May; 60(5):702-9. View in: PubMed

Loo J, Selby R, Genyk Y, Sher L, Alexopoulos S, Stapfer M. Removal of a large hepatic neuroendocrine tumor causing Budd-Chiari syndrome using a median sternotomy approach in conjunction with a midline laparotomy incision. Am Surg. 2011 Feb; 77(2):E27-9. View in: PubMed

Mateo R, Stapfer M, Almeda J, Selby R, Genyk Y. Alternate method to secure the aorta for organ perfusion in donation after cardiac death donors. Transpl Int. 2008 Dec; 21(12):1190-1. View in: PubMed

Mateo R, Stapfer M, Sher L, Selby R, Genyk Y. Intraoperative umbilical herniorrhaphy during liver transplantation. Surgery. 2008 Mar; 143(3):451-2. View in: PubMed

Mateo R, Tsai S, Stapfer MV, Sher LS, Selby R, Genyk YS. Ischemic mass effect from biliary surgical clips. J Laparoendosc Adv Surg Tech A. 2008 Feb; 18(1):84-7. View in: PubMed

Chapman WC, Singla N, Genyk Y, McNeil JW, Renkens KL, Reynolds TC, Murphy A, Weaver FA. A phase 3, randomized, double-blind comparative study of the efficacy and safety of topical recombinant human thrombin and bovine thrombin in surgical hemostasis. J Am Coll Surg. 2007 Aug; 205(2):256-65. View in: PubMed

Mateo R, Henderson R, Jabbour N, Gagandeep S, Goldsberry A, Sher L, Qazi Y, Selby RR, Genyk Y. Living related donor nephrectomy in transfusion refusing donors. Transpl Int. 2007 Jun; 20(6):490-6. View in: PubMed

Mateo R, Singh G, Sher L, Selby R, Genyk Y. Utility versus utilization of DCD liver allografts. Am J Transplant. 2007 Jan; 7(1):263. View in: PubMed

Clarke T, Matsuoka L, Jabbour N, Mateo R, Genyk Y, Selby R, Gagandeep S. Gallbladder mass with a carbohydrate antigen 19-9 level in the thousands: malignant or benign pathology? Report of a case. Surg Today. 2007; 37(4):342-4. View in: PubMed

Jabbour N, Gagandeep S, Shah H, Mateo R, Stapfer M, Genyk Y, Sher L, Zwierzchoniewska M, Selby R, Zeger G. Impact of a transfusion-free program on non-Jehovah's Witness patients undergoing liver transplantation. Arch Surg. 2006 Sep; 141(9):913-7. View in: PubMed

Gagandeep S, Artinyan A, Jabbour N, Mateo R, Matsuoka L, Sher L, Genyk Y, Selby R. Extended pancreatectomy with resection of the celiac axis: the modified Appleby operation. Am J Surg. 2006 Sep; 192(3):330-5. View in: PubMed

Gagandeep S, Matsuoka L, Mateo R, Cho YW, Genyk Y, Sher L, Cicciarelli J, Aswad S, Jabbour N, Selby R. Expanding the donor kidney pool: utility of renal allografts procured in a setting of uncontrolled cardiac death. Am J Transplant. 2006 Jul; 6(7):1682-8. View in: PubMed

Heestand G, Morrison B, Correa A, Palmer S, Mateo R, Hagen J, Genyk Y, Selby R, Sher L. Gallstone-induced inflammatory fibrosis: a relentless clinical course of retained gallstones after laparoscopic cholecystectomy. Am Surg. 2006 Apr; 72(4):303-6. View in: PubMed

Mateo R, Cho Y, Singh G, Stapfer M, Donovan J, Kahn J, Fong TL, Sher L, Jabbour N, Aswad S, Selby RR, Genyk Y. Risk factors for graft survival after liver transplantation from donation after cardiac death donors: an analysis of OPTN/UNOS data. Am J Transplant. 2006 Apr; 6(4):791-6. View in: PubMed

Zaghla H, Selby RR, Chan LS, Kahn JA, Donovan JA, Jabbour N, Genyk Y, Mateo R, Gagandeep S, Sher LS, Ramicone E, Fong TL. A comparison of sirolimus vs. calcineurin inhibitor-based immunosuppressive therapies in liver transplantation. Aliment Pharmacol Ther. 2006 Feb 15; 23(4):513-20. View in: PubMed

Jabbour N, Gagandeep S, Genyk Y, Selby R, Mateo R. Caval preservation with reconstruction of the hepatic veins using caval-common iliac bifurcation graft for domino liver transplantation. Liver Transpl. 2006 Feb; 12(2):324-5. View in: PubMed

Christensen T, Matsuoka L, Heestand G, Palmer S, Mateo R, Genyk Y, Selby R, Sher L. Iatrogenic pseudoaneurysms of the extrahepatic arterial vasculature: management and outcome. HPB (Oxford). 2006; 8(6):458-64. View in: PubMed

Mateo R, Stapfer M, Singh G, Sher L, Jabbour N, Selby RR, Genyk Y. Pancreaticoduodenectomy in adults with congenital intestinal rotation disorders. Pancreas. 2005 Nov; 31(4):413-5. View in: PubMed

Jabbour N, Gagandeep S, Mateo R, Sher L, Genyk Y, Selby R. Transfusion free surgery: single institution experience of 27 consecutive liver transplants in Jehovah's Witnesses. J Am Coll Surg. 2005 Sep; 201(3):412-7. View in: PubMed

Jabbour N, Gagandeep S, Bramstedt KA, Brenner M, Mateo R, Selby R, Genyk Y. To do or not to do living donor hepatectomy in Jehovah's Witnesses: single institution experience of the first 13 resections. Am J Transplant. 2005 May; 5(5):1141-5. View in: PubMed

Jabbour N, Brenner M, Gagandeep S, Lin A, Genyk Y, Selby R, Mateo R. Major hepatobiliary surgery during pregnancy: safety and timing. Am Surg. 2005 Apr; 71(4):354-8. View in: PubMed

Mateo R, Singh G, Jabbour N, Palmer S, Genyk Y, Roman L. Optimal cytoreduction after combined resection and radiofrequency ablation of hepatic metastases from recurrent malignant ovarian tumors. Gynecol Oncol. 2005 Apr; 97(1):266-70. View in: PubMed

Jabbour N, Gagandeep S, Thomas D, Stapfer M, Mateo R, Sher L, Selby R, Genyk Y. Transfusion-free techniques in pediatric live donor liver transplantation. J Pediatr Gastroenterol Nutr. 2005 Apr; 40(4):521-3. View in: PubMed

Jabbour N, Gagandeep S, Peilin AC, Boland B, Mateo R, Genyk Y, Selby R, Zeger G. Recombinant human coagulation factor VIIa in Jehovah's Witness patients undergoing liver transplantation. Am Surg. 2005 Feb; 71(2):175-9. View in: PubMed

Jabbour N, Gagandeep S, Mateo R, Sher L, Strum E, Donovan J, Kahn J, Peyre CG, Henderson R, Fong TL, Selby R, Genyk Y. Live donor liver transplantation without blood products: strategies developed for Jehovah's Witnesses offer broad application. Ann Surg. 2004 Aug; 240(2):350-7. View in: PubMed

Young R, Gagandeep S, Grant E, Palmer S, Mateo R, Selby R, Genyk Y, Jabbour N. Gastroduodenal artery pseudoaneurysm secondary to pancreatic head biopsy. J Ultrasound Med. 2004 Jul; 23(7):997-1001. View in: PubMed

Peyré CG, Wakim M, Mateo R, Genyk Y, Singh G, Selby RR, Jabbour N. Unusual cases of jaundice secondary to non-neoplastic bile duct obstruction. Am Surg. 2004 Jul; 70(7):620-4. View in: PubMed

Hall J, Singh G, Hood D, Mateo R, Weaver F, Selby R, Genyk Y, Jabbour N. Management of an abdominal aortic aneurysm in a patient with end-stage liver disease. Am J Transplant. 2004 Apr; 4(4):666-8. View in: PubMed

Ferdman RM, Wakim M, Church JA, Hofstra TC, Thomas D, Genyk YS. Rapid intravenous desensitization to antithymocyte globulin in a patient with aplastic anemia. Transplantation. 2004 Jan 27; 77(2):321-3. View in: PubMed

Jabbour N, Gagandeep S, Mateo R, Sher L, Henderson R, Selby R, Genyk Y. Live donor liver transplantation: staging hepatectomy in a Jehovah's Witness recipient. J Hepatobiliary Pancreat Surg. 2004; 11(3):211-4. View in: PubMed

Jabbour N, Gagandeep S, Mateo R, Sher L, Selby R, Genyk Y. Left portahepatic shunt: a novel technique to decrease excessive portal venous inflow during live donor liver transplantation. J Am Coll Surg. 2003 Dec; 197(6):1056-7. View in: PubMed

Heestand G, Sher L, Lightfoote J, Palmer S, Mateo R, Singh G, Moser J, Selby R, Genyk Y, Jabbour N. Characteristics and management of splenic artery aneurysm in liver transplant candidates and recipients. Am Surg. 2003 Nov; 69(11):933-40. View in: PubMed

Mateo RB, Sher L, Jabbour N, Singh G, Chan L, Selby RR, El-Shahawy M, Genyk Y. Comparison of outcomes in noncomplicated and in higher-risk donors after standard versus hand-assisted laparoscopic nephrectomy. Am Surg. 2003 Sep; 69(9):771-8. View in: PubMed

Gagandeep S, Jabbour N, Genyk Y, Selby R. Restricting fresh frozen plasma in hepatic resections. J Am Coll Surg. 2003 Aug; 197(2):339-40. View in: PubMed

Jabbour N, Shirazi SK, Genyk Y, Mateo R, Pak E, Cosenza DC, Peyré CG, Selby RR. Surgical management of complicated hydatid disease of the liver. Am Surg. 2002 Nov; 68(11):984-8. View in: PubMed

Khan AA, Parekh D, Cho Y, Ruiz R, Selby RR, Jabbour N, Genyk YS, Mateo R. Improved prediction of outcome in patients with severe acute pancreatitis by the APACHE II score at 48 hours after hospital admission compared with the APACHE II score at admission. Acute Physiology and Chronic Health Evaluation. Arch Surg. 2002 Oct; 137(10):1136-40. View in: PubMed

Genyk YS, Quiros JA, Jabbour N, Selby RR, Thomas DW. Liver transplantation in cystic fibrosis. Curr Opin Pulm Med. 2001 Nov; 7(6):441-7. View in: PubMed

Jabbour N, Genyk Y, Mateo R, Peyre C, Patel RV, Thomas D, Ralls P, Palmer S, Kanel G, Selby RR. Live-donor liver transplantation: the USC experience. Acta Chir Belg. 2001 Sep-Oct; 101(5):220-3. View in: PubMed

Selby R, Genyk Y, Jabbour N. Organs for transplantation. N Engl J Med. 2000 Dec 7; 343(23):1731; author reply 1732. View in: PubMed

Emre S, Genyk Y, Schluger LK, Fishbein TM, Guy SR, Sheiner PA, Schwartz ME, Miller CM. Treatment of tacrolimus-related adverse effects by conversion to cyclosporine in liver transplant recipients. Transpl Int. 2000; 13(1):73-8. View in: PubMed

Genyk Y, Knight R, Burrows L. Should pediatric donors younger than 2 years of age be used in kidney transplantation? Transplant Proc. 1997 Dec; 29(8):3276-7. View in: PubMed

Genyk Y, Burrows L, Knight RJ. Kidney transplantation utilizing donors from both age extremes. Transplant Proc. 1997 Dec; 29(8):3655-6. View in: PubMed

Travis DL, Paulsen AW, Genyk Y. Development of an in situ isolated porcine liver perfusion model for tightly controlled physiologic and pharmacologic studies. J Invest Surg. 1996 Mar-Apr; 9(2):131-47. View in: PubMed

Husberg BS, Genyk YS, Klintmalm GB. A new rat model for studies of the ischemic injury after transplantation of fatty livers: improvement after postoperative administration of prostaglandin. Transplantation. 1994 Feb; 57(3):457-8. View in: PubMed

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