Faculty

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Zhang-Xu Liu, MD, PhD
Assistant Professor of Research Medicine
Medicine
HMR 803 Health Sciences Campus Los Angeles
+1 323 442 3233

Overview

Dr. Liu's research interests include fucnation of liver NK and NKT cells, liver immunology and diseases, innate immunity in drug-induced hepatotoxicity, and immunity in alcoholic hepatitis. He is currently an Associate Editor of World Journal of Gastroenterology.

Dr. Liu earned his medical degree from Chongqing Medical University. He then went on to complete his master's degree at Sichuan University West China Medical School, followed by a PhD from Tohoku University School of Medicine.

Awards

Japanese Government (Mobusho): Fellowship, 1992-1997

Japanese Society of Gastroenterology: Award, 1997

American Digestive Health Foundation: Travel Award, 1999

American Digestive Health Foundation: award conferred by, 1999

Japanese Government (Mobusho): award conferred by, 1992-1997

American Digestive Health Foundation: has faculty rank, 1999

Japanese Society of Gastroenterology: has faculty rank, 1997

Japanese Government (Mobusho): has faculty rank, 1992-1997

American Digestive Health Foundation: award or honor for, 1999

Japanese Society of Gastroenterology: award or honor for, 1997

Japanese Government (Mobusho): award or honor for, 1992-1997

American Digestive Health Foundation: full name, 1999

Japanese Government (Mobusho): full name, 1992-1997

Japanese Society of Gastroenterology: person in primary position, 1997

Japanese Government (Mobusho): person in primary position, 1992-1997

American Digestive Health Foundation: person in primary position, 1999

Japanese Government (Mobusho): last name, 1992-1997

Japanese Society of Gastroenterology: last name, 1997

American Digestive Health Foundation: last name, 1999

American Digestive Health Foundation: HR job title, 1999

Japanese Society of Gastroenterology: HR job title, 1997

Japanese Government (Mobusho): HR job title, 1992-1997

Japanese Society of Gastroenterology: full name, 1997

Japanese Government (Mobusho): position in department, 1992-1997

American Digestive Health Foundation: position in department, 1999

Japanese Society of Gastroenterology: position in department, 1997

Japanese Society of Gastroenterology: sort order, 1997

Japanese Government (Mobusho): sort order, 1992-1997

American Digestive Health Foundation: sort order, 1999

Japanese Government (Mobusho): Faculty Rank, 1992-1997

American Digestive Health Foundation: Faculty Rank, 1999

Japanese Society of Gastroenterology: Faculty Rank, 1997

Japanese Government (Mobusho): Assistant Professor, 1992-1997

American Digestive Health Foundation: Assistant Professor, 1999

Japanese Society of Gastroenterology: Assistant Professor, 1997

Japanese Government (Mobusho): email address, 1992-1997

Japanese Society of Gastroenterology: email address, 1997

American Digestive Health Foundation: email address, 1999

Japanese Society of Gastroenterology: start date, 1997

American Digestive Health Foundation: start date, 1999

Japanese Government (Mobusho): start date, 1992-1997

Japanese Society of Gastroenterology: award conferred by, 1997

American Digestive Health Foundation: type, 1999

Japanese Government (Mobusho): type, 1992-1997

Japanese Society of Gastroenterology: type, 1997

Japanese Society of Gastroenterology: Person ID, 1997

American Digestive Health Foundation: Person ID, 1999

Japanese Government (Mobusho): Person ID, 1992-1997

Japanese Government (Mobusho): end date, 1992-1997

Japanese Government (Mobusho): workplace homepage, 1992-1997

American Digestive Health Foundation: workplace homepage, 1999

American Digestive Health Foundation: Keck School of Medicine of USC, 1999

Japanese Government (Mobusho): Keck School of Medicine of USC, 1992-1997

Japanese Government (Mobusho): label, 1992-1997

American Digestive Health Foundation: label, 1999

Japanese Society of Gastroenterology: label, 1997

Japanese Society of Gastroenterology: Liu, Zhang-Xu, 1997

Japanese Government (Mobusho): Liu, Zhang-Xu, 1992-1997

American Digestive Health Foundation: is primary position, 1999

Japanese Government (Mobusho): is primary position, 1992-1997

Japanese Society of Gastroenterology: is primary position, 1997

Japanese Government (Mobusho): preferred title, 1992-1997

Japanese Society of Gastroenterology: preferred title, 1997

American Digestive Health Foundation: preferred title, 1999

Japanese Society of Gastroenterology: Person, 1997

Japanese Government (Mobusho): Person, 1992-1997

American Digestive Health Foundation: Person, 1999

American Digestive Health Foundation: Agent, 1999

Japanese Society of Gastroenterology: Agent, 1997

Japanese Government (Mobusho): Agent, 1992-1997

Japanese Society of Gastroenterology: first name, 1997

American Digestive Health Foundation: first name, 1999

Japanese Government (Mobusho): first name, 1992-1997

American Digestive Health Foundation: Liu, Zhang-Xu, 1999

American Digestive Health Foundation: Organization, 1999

Japanese Government (Mobusho): Organization, 1992-1997

Japanese Society of Gastroenterology: Organization, 1997

Japanese Society of Gastroenterology: Keck School of Medicine of USC, 1997

Japanese Society of Gastroenterology: Assistant Professor of Research Medicine, 1997

American Digestive Health Foundation: Assistant Professor of Research Medicine, 1999

Japanese Government (Mobusho): Assistant Professor of Research Medicine, 1992-1997

Japanese Government (Mobusho): Position, 1992-1997

Japanese Society of Gastroenterology: Position, 1997

American Digestive Health Foundation: Position, 1999

Japanese Society of Gastroenterology: position in organization, 1997

Japanese Government (Mobusho): position in organization, 1992-1997

American Digestive Health Foundation: position in organization, 1999

Japanese Society of Gastroenterology: photo, 1997

American Digestive Health Foundation: photo, 1999

Japanese Government (Mobusho): photo, 1992-1997

Publications

Mechanisms of adaptation and progression in idiosyncratic drug induced liver injury, clinical implications. Liver Int. 2016 Feb; 36(2):158-65. View in: PubMed

Targeting signal transduction pathways which regulate necrosis in acetaminophen hepatotoxicity. J Hepatol. 2015 Jul; 63(1):5-7. View in: PubMed

Celecoxib attenuates hepatic cirrhosis through inhibition of epithelial-to-mesenchymal transition of hepatocytes. J Gastroenterol Hepatol. 2014 Nov; 29(11):1932-42. View in: PubMed

Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria. Trends Pharmacol Sci. 2013 Apr; 34(4):243-53. View in: PubMed

Celecoxib ameliorates portal hypertension of the cirrhotic rats through the dual inhibitory effects on the intrahepatic fibrosis and angiogenesis. PLoS One. 2013; 8(7):e69309. View in: PubMed

Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. Alcohol Clin Exp Res. 2011 Aug; 35(8):1509-18. View in: PubMed

How to protect against acetaminophen: don't ask for JUNK. Gastroenterology. 2008 Oct; 135(4):1047-51. View in: PubMed

Role of innate immunity in acetaminophen-induced hepatotoxicity. Expert Opin Drug Metab Toxicol. 2006 Aug; 2(4):493-503. View in: PubMed

c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity. Gastroenterology. 2006 Jul; 131(1):165-78. View in: PubMed

Neutrophil depletion protects against murine acetaminophen hepatotoxicity. Hepatology. 2006 Jun; 43(6):1220-30. View in: PubMed

Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity. Gastroenterology. 2004 Dec; 127(6):1760-74. View in: PubMed

Activated natural killer T cells induce liver injury by Fas and tumor necrosis factor-alpha during alcohol consumption. Gastroenterology. 2004 May; 126(5):1387-99. View in: PubMed

IP-10 and Mig facilitate accumulation of T cells in the virus-infected liver. Cell Immunol. 2002 Sep; 219(1):48-56. View in: PubMed

Immune-mediated drug-induced liver disease. Clin Liver Dis. 2002 Aug; 6(3):755-74. View in: PubMed

Hepatitis C virus genotype 1b core protein does not exert immunomodulatory effects on virus-induced cellular immunity. J Virol. 2002 Feb; 76(3):990-7. View in: PubMed

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