The Zika virus has spread to 44 countries, with thousands infected and thousands of babies born with microcephaly, a rare complication that causes small heads. But even though research dollars are being poured into understanding the virus, there are still numerous outstanding questions. USC Assistant Professor Jianfu Chen is working to answer some of the persistent questions about the virus.
Researchers are hard at work building mini-kidneys from human cells — using blueprints mostly drawn from lab mice. But mouse kidneys differ from their human counterparts in more than mere scale, as detailed by the USC Stem Cell laboratory of Andy McMahon in three studies in the Journal of the American Society of Nephrology.
In the study, Yingxiao TK Shi and Shaoyu Sebastian Lin in the laboratory of Justin Ichida describe how a mutation in a gene, called C9ORF72, leads to toxicity in nerve cells—causing 10 percent of all cases of ALS, and an additional 10 percent of FTD.
When RCGD 423 was applied to joint cartilage cells in the laboratory, the cells proliferated more and died less, and when injected into the knees of rats with damaged cartilage, the animals could more effectively heal their injuries.
Malcolm Snead, a professor at the Ostrow School of Dentistry of USC and a principal investigator with USC Stem Cell, has been elected to the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows.
Scientists in the USC Stem Cell laboratory of Gage Crump have revealed how key genes guide the development of the jaw in zebrafish. These findings may offer clues for understanding craniofacial anomalies in human patients.
Bérénice Benayoun, assistant professor at the USC Leonard Davis School of Gerontology and principal investigator with USC Stem Cell, explores the role of epigenetics—the ways that genes turn “off” or “on”.
This year’s Broad Clinical Research Fellows will apply stem cell-based approaches to two prevalent problems: non-healing bone injuries, which affect 5 million Americans each year; and neuroblastoma, which ... Read More »
Pursuing her passion for cardiovascular research, Susana Cavallero has journeyed from her hometown of Polvaredas in Saladillo, Argentina, to Buenos Aires to Los Angeles, where she is an ... Read More »