In the developing face, how do stem cells know whether to become cartilage, bones or teeth? To begin to answer this question, scientists from the USC Stem Cell laboratory of Gage Crump tested the role of a key family of genes, called “Forkhead-domain transcription factors,” or Fox. Their findings appear in the journal Development.
According to a new study in Developmental Cell from the USC Stem Cell laboratory of Andy McMahon, the progenitor cells that form the kidney’s filtering units, called nephrons, mature into entirely different types of cells based on when they arrive to the scene of nephron formation.
A USC research team identified 150 proteins affecting cell activity and brain development that contribute to mental disorders, including schizophrenia, bipolar condition and depression.
How do complex biological structures—an eye, a hand, a brain—emerge from a single fertilized egg? This is the fundamental question of developmental biology, and a mystery...
In your body, blood stem cells produce approximately 10 billion new white blood cells, which are also known as immune cells, each and every day.
USC Stem Cell researchers from the laboratory of Min Yu have positive news for patients with triple-negative breast cancer (TNBC), the most deadly type of breast cancer.
Tubular networks developing in a mammalian kidney (Image by Tracy Tran/Andy McMahon Lab) Stem cell therapies have accelerated at a promising pace, but how do they ... Read More »
Kidney (Image by Lori O'Brien/Andy McMahon Lab, illustration by Mira Nameth) If you lose a limb, it’s lost for life. If you damage a kidney, you ... Read More »
In USC’s Department of Stem Cell Biology and Regenerative Medicine, half of the faculty members are assistant professors, poised at the threshold of their careers in biomedical research. One of these promising pioneers, ALS researcher Justin Ichida, has been chosen as the first of four USC Richard N. Merkin Scholars.