{"id":41,"date":"2023-11-15T20:41:28","date_gmt":"2023-11-15T20:41:28","guid":{"rendered":"https:\/\/keck.usc.edu\/cell-therapy-program\/?page_id=41"},"modified":"2024-11-25T17:34:02","modified_gmt":"2024-11-25T17:34:02","slug":"cgmp-facility","status":"publish","type":"page","link":"https:\/\/keck.usc.edu\/cell-therapy-program\/services\/cgmp-facility\/","title":{"rendered":"cGMP Facility"},"content":{"rendered":"\n\n\n\n\n    \n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--hero-primary horizontal-navigation\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--hero-primary\"\n    \n      >\n\n    \n  \n  <div class=\"inner-wrapper has-horizontal-nav\">\n\n          <div class=\"title-wrapper\">\n\n                  <div class=\"eyebrow-container\">\n                              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <a href=\"https:\/\/keck.usc.edu\/cell-therapy-program\/\"  aria-label=\"Read more about USC\/CHLA Cell Therapy Program\">USC\/CHLA Cell Therapy Program<\/a>\n\n\n\n<\/div>\n                              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <a href=\"https:\/\/keck.usc.edu\/cell-therapy-program\/services\/\"  aria-label=\"Read more about Services\">Services<\/a>\n\n\n\n<\/div>\n                      <\/div>\n        \n                      \n<div class=\"f--field f--page-title has-stripe\">\n\n    \n  <h1>cGMP Facility<\/h1>\n\n\n<\/div>\n        \n              <\/div>\n    \n              \n<div class=\"f--field f--link eyebrow-link\">\n\n    \n    \n  \n<a\n  class=\"link \"\n  href=\"https:\/\/www.keckmedicine.org\/find-a-doctor\/\"\n  target=\"_blank\"  aria-label=\"Read&#x20;more&#x20;about&#x20;Are&#x20;You&#x20;a&#x20;Patient&#x3F;\">\n        Are You a Patient?\n    <\/a>\n\n\n<\/div>\n    \n    \n      \n              <div class=\"horizontal-nav\">\n                      <div class=\"horizontal-menu-container\">\n              <button class=\"expand-menu\">\n                                  In This Section\n                                <svg class=\"menu\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\"\n                  y=\"0px\" viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" xml:space=\"preserve\">\n                  <path fill-rule=\"evenodd\" clip-rule=\"evenodd\" fill=\"#000\" d=\"M4,23h3v3H4V23z M4,16h3v3H4V16z M10,23\n                  h21v3H10V23z M10,16h21v3H10V16z M10,9h21v3H10V9z M4,9h3v3H4V9z\"\/>\n                <\/svg>\n\n                <svg class=\"close\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\" y=\"0px\"\n                  viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" xml:space=\"preserve\">\n                  <polygon fill=\"#000\" fill-rule=\"evenodd\" clip-rule=\"evenodd\" points=\"26,10.4 24.6,9 17.5,16.1 10.4,9 9,10.4 16.1,17.5\n                  9,24.6 10.4,26 17.5,18.9 24.6,26 26,24.6 18.9,17.5 \"\/>\n                <\/svg>\n              <\/button>\n\n              <nav\n  class=\"mc--menu mc--\"\n  >\n  <ul class=\"m--menu m--\">\n    \n    \n      <li class=\" menu-item menu-item-type-custom menu-item-object-custom menu-item-18\">\n      <a href=\"\/cell-therapy-program\/\" >Cell Therapy Program<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-17 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/cell-therapy-program\/about\/\" >About<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for About\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-51\">\n      <a href=\"https:\/\/keck.usc.edu\/cell-therapy-program\/about\/our-team\/\" >Our Team<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-79\">\n      <a href=\"https:\/\/keck.usc.edu\/cell-therapy-program\/about\/careers\/\" >Careers<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <li class=\"has-submenu menu-item menu-item-type-post_type menu-item-object-page menu-item-22 menu-item-has-children\">\n      <div class=\"link-arrow-wrapper\">\n      <a href=\"https:\/\/keck.usc.edu\/cell-therapy-program\/services\/\" >Services<\/a>\n\n      <button class=\"expand-children has-submenu arrow-toggle\" aria-expanded=\"false\" aria-haspopup=\"true\" aria-label=\"Display Submenu for Services\">\n        <svg height=\"35\" viewBox=\"0 0 35 35\" width=\"35\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n          <path d=\"m17.5 20.2142857 6.2142857-6.2142857 1.2857143 1.2857143-7.5 7.5-7.5-7.5 1.2857143-1.2857143z\" fill=\"#000\" fill-rule=\"evenodd\"\/>\n        <\/svg>\n      <\/button>\n    <\/div>\n  \n      <div class=\"submenus-wrapper\">\n      <div class=\"submenus-wrapper-inner\">\n        <ul class=\"submenu\" aria-hidden=\"true\">\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-48\">\n      <a href=\"https:\/\/keck.usc.edu\/cell-therapy-program\/services\/cgmp-facility\/\" >cGMP Facility<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n   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class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <h2 style=\"text-align: center\">cGMP Facility<\/h2>\n<p>With the final facility design completed in the midst of the COVID-19 pandemic, initial construction took place in early 2021. Within a year, the facility was fully constructed and commissioned. Such an efficient and speedy process concurred with equipment purchase and other supporting laboratories completion. With new projects lining up, the facility became operational in 2023.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-42\" src=\"https:\/\/keck.usc.edu\/cell-therapy-program\/wp-content\/uploads\/sites\/82\/2023\/11\/Picture3.png\" alt=\"Three images of the cGMP facility\" width=\"912\" height=\"313\" srcset=\"https:\/\/keck.usc.edu\/cell-therapy-program\/wp-content\/uploads\/sites\/82\/2023\/11\/Picture3.png 912w, https:\/\/keck.usc.edu\/cell-therapy-program\/wp-content\/uploads\/sites\/82\/2023\/11\/Picture3-300x103.png 300w, https:\/\/keck.usc.edu\/cell-therapy-program\/wp-content\/uploads\/sites\/82\/2023\/11\/Picture3-768x264.png 768w\" sizes=\"auto, (max-width: 912px) 100vw, 912px\" \/><\/p>\n<h3 class=\"fusion-responsive-typography-calculated\" data-fontsize=\"24\" data-lineheight=\"36px\">The facility operates the following equipment:<\/h3>\n<ul>\n<li>Dedicated ISO 5 biosafety cabinets<\/li>\n<li>Incubators, centrifuges, plasma extractors, automatic cell counters, microscopes with high resolution cameras and balances.<\/li>\n<li>Miltenyi CliniMACS equipment for positive or negative cell selection of hematopoietic stem cells, mesenchymal stromal cells, monocytes, dendritic cells, NK cells, B or T cells subsets.<\/li>\n<li>Multiple Miltenyi Prodigy instruments that allow cell selection, transduction, cell expansion in a functionally closed system<\/li>\n<li>Optima XE ultracentrifuge for viral vector production<\/li>\n<li>Controlled rate freezer for cryopreservation of cells<\/li>\n<li>LN2 tanks for cryostorage<\/li>\n<\/ul>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--featured-block image-left white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--featured-block\"\n    \n      >\n\n    \n  <div class=\"text-image-container\">\n    <div class=\"text-container\">\n\n                  \n<div class=\"f--field f--eyebrow\">\n\n    \n  <span>Quality Control<\/span>\n\n\n\n<\/div>\n      \n                  \n<div class=\"f--field f--section-title has-stripe\">\n\n    \n  <h2>\n          Testing Platforms\n      <\/h2>\n\n\n<\/div>\n      \n                  \n<div class=\"f--field f--description description-medium\">\n\n    \n  <ul>\n<li>BD FACSLyric 12 color Flow Cytometer<\/li>\n<li>BD Bactec FX40<\/li>\n<li>Endosafe\u00ae nexgen-PTS\u2122<\/li>\n<li>CFX Opus 96 Real-Time PCR<\/li>\n<li>C1000 touch thermal cycler with dual 48\/48 fast reaction module<\/li>\n<li>Microbiological incubators<\/li>\n<li>Biofire Filmarray<\/li>\n<\/ul>\n\n\n\n<\/div>\n      \n      \n    <\/div>\n\n          <div class=\"image-container\">\n            \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/keck.usc.edu\/cell-therapy-program\/wp-content\/uploads\/sites\/82\/2023\/11\/square-cgmp-768x768.jpg\"\n          data-srcset=\"https:\/\/keck.usc.edu\/cell-therapy-program\/wp-content\/uploads\/sites\/82\/2023\/11\/square-cgmp-1280x1280.jpg 1280w,https:\/\/keck.usc.edu\/cell-therapy-program\/wp-content\/uploads\/sites\/82\/2023\/11\/square-cgmp-768x768.jpg 768w\"          data-sizes=\"(min-width:1024px) 50vw, (min-width:768px) 100vw, 100vw\"          class=\"lazyload\"\n        \n        alt=\"Facility staff in protective gear with pipettes\"\n        \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n      <\/div>\n    \n  <\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":3,"featured_media":0,"parent":20,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"footnotes":""},"class_list":["post-41","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - 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