{"id":116,"date":"2024-04-05T17:23:16","date_gmt":"2024-04-05T17:23:16","guid":{"rendered":"https:\/\/keck.usc.edu\/cpbh\/?page_id=116"},"modified":"2025-08-11T00:49:59","modified_gmt":"2025-08-11T07:49:59","slug":"exploring-brain-health","status":"publish","type":"page","link":"https:\/\/keck.usc.edu\/cpbh\/community-outreach\/exploring-brain-health\/","title":{"rendered":"Exploring Brain Health"},"content":{"rendered":"\n\n\n\n\n    \n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--hero-primary horizontal-navigation\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--hero-primary\"\n    \n      >\n\n    \n  \n  <div class=\"inner-wrapper has-horizontal-nav\">\n\n          <div class=\"title-wrapper\">\n\n                  <div class=\"eyebrow-container\">\n                              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <a href=\"https:\/\/keck.usc.edu\/cpbh\/\" >USC Center for Personalized Brain Health<\/a>\n\n\n\n<\/div>\n                              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <a href=\"https:\/\/keck.usc.edu\/cpbh\/community-outreach-2\/\" >Community Outreach<\/a>\n\n\n\n<\/div>\n                      <\/div>\n        \n                      \n<div class=\"f--field f--page-title has-stripe\">\n\n    \n      <h1>Exploring Brain Health<\/h1>\n\n\n<\/div>\n        \n              <\/div>\n    \n              \n<div class=\"f--field f--link eyebrow-link\">\n\n    \n    \n  \n\n<a\n  class=\"link \"\n  href=\"https:\/\/giveto.usc.edu\/?fundid=GF1908144&#038;appealcode=WK24WG335&#038;radioamount0=25&#038;radioamount1=100&#038;radioamount2=500&#038;radioamount3=1000&#038;radioamount4=2500&#038;buttongen=1&#038;blankradio=true&#038;hidetop=1\"\n  target=\"_blank\"  >\n        Give Now\n    <\/a>\n\n\n<\/div>\n    \n    \n      \n              <div class=\"horizontal-nav\">\n                      <div class=\"horizontal-menu-container\">\n              <button class=\"expand-menu\">\n                   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 <a href=\"https:\/\/keck.usc.edu\/cpbh\/community-outreach\/exploring-brain-health\/\" >Exploring Brain Health<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-291\">\n      <a href=\"https:\/\/keck.usc.edu\/cpbh\/community-outreach\/community-resources\/\" >Community Resources<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-807\">\n      <a href=\"https:\/\/keck.usc.edu\/cpbh\/newsletter\/\" >Newsletter<\/a>\n  \n  \n<\/li>\n                      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-969\">\n      <a href=\"https:\/\/keck.usc.edu\/cpbh\/cpbh-research-symposium-events\/\" >Events<\/a>\n  \n  \n<\/li>\n                  <\/ul>\n      <\/div>\n    <\/div>\n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-683\">\n      <a href=\"https:\/\/keck.usc.edu\/cpbh\/give-now\/\" >Give Now<\/a>\n  \n  \n<\/li>\n\n    \n      <li class=\" menu-item menu-item-type-post_type menu-item-object-page menu-item-698\">\n      <a href=\"https:\/\/keck.usc.edu\/cpbh\/contact\/\" >Contact<\/a>\n  \n  \n<\/li>\n\n    \n      <\/ul><!-- m--menu -->\n<\/nav>\n\n            <\/div>\n                  <\/div>\n        <\/div>\n\n\n  <\/div><\/div>\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <h2 style=\"text-align: center\">What is Alzheimer&#8217;s Disease?<\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-112\" src=\"https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/04\/iStock-1173747407-300x225.jpg\" alt=\"Young female volunteer is caring for an elderly person with dementia. Senior person leans on a cane, and a young social worker supports and helps him. Flat style vector illustration\" width=\"420\" height=\"315\" srcset=\"https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/04\/iStock-1173747407-300x225.jpg 300w, https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/04\/iStock-1173747407-1024x768.jpg 1024w, https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/04\/iStock-1173747407-768x576.jpg 768w, https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/04\/iStock-1173747407.jpg 1183w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/>Alzheimer\u2019s disease is the most common type of dementia. The brain cells, or neurons, die and connections between them are lost, leading to problems with memory, thinking, and behavior. Alzheimer\u2019s disease is a progressive brain disorder that gradually destroys cognitive abilities, making it increasingly difficult for people to carry out daily activities. Symptoms usually develop slowly and worsen over time.<\/p>\n<p>The cause of Alzheimer\u2019s is not fully understood, but it is believed to be a combination of genetic, lifestyle and environmental factors. There is no cure for Alzheimer\u2019s, but treatments can help slow the progression of the disease and improve quality of life for those living with it.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n      \n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--statistics \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--statistics\"\n    \n      >\n\n    \n      <div class=\"header-container\">\n\n                  \n<div class=\"f--field f--section-title\">\n\n    \n      <h2>\n          Alzheimer&#8217;s Statistics\n      <\/h2>\n\n\n<\/div>\n      \n          <\/div>\n  \n    \n      <div class=\"stats-container\">\n                          <div class=\"stat\">\n                \n                                    <span><p>Over 6 million Americans are living with Alzheimer\u2019s<\/p>\n<\/span>\n                \n            <\/div>\n                                  <div class=\"stat\">\n                \n                                    <span><p>55 million people have dementia worldwide and there are nearly 10 million new cases every year<\/p>\n<\/span>\n                \n            <\/div>\n                                  <div class=\"stat\">\n                \n                                    <span><p>The annual global cost of dementia is now above $ 1.3 trillion<\/p>\n<\/span>\n                \n            <\/div>\n                  <\/div>\n  \n\n  <\/div><\/div>\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <h2 style=\"text-align: center\">What Is the <em>APOE<\/em> Gene?<\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-118\" src=\"https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/04\/iStock-907327088-300x210.jpg\" alt=\"3D illustration. DNA Sanger Sequencing and a Magnifying Glass Showing the DNA Helix.\" width=\"420\" height=\"294\" srcset=\"https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/04\/iStock-907327088-300x210.jpg 300w, https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/04\/iStock-907327088-1024x717.jpg 1024w, https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/04\/iStock-907327088-768x538.jpg 768w, https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/04\/iStock-907327088.jpg 1224w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/>The apolipoprotein E (<em>APOE<\/em>) gene provides instructions for making a protein that plays a role in the transport and processing of fats in the body. There are three different versions, or alleles, of the <em>APOE<\/em> gene: \u03b52, \u03b53, and \u03b54.<\/p>\n<p>The <em>APOE<\/em> gene is associated with an increased risk of developing Alzheimer\u2019s disease. Having one copy of the \u03b54 allele of the <em>APOE<\/em> gene increases a person\u2019s risk of developing Alzheimer\u2019s disease. The risk is even higher if a person has two copies of the \u03b54 allele. Having the \u03b54 allele does not mean that a person will definitely develop Alzheimer\u2019s, only that their risk is higher.<\/p>\n<p><em>APOE<\/em> is not the only gene associated with Alzheimer\u2019s, and there are other factors that also play a role. Many people who develop the disease do not have a family history or a known genetic risk factor. Additionally, lifestyle and environmental factors, such as diet, exercise, and head injury, can also play a role in the development of the disease.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n      \n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--statistics \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--statistics\"\n    \n      >\n\n    \n      <div class=\"header-container\">\n\n                  \n<div class=\"f--field f--section-title\">\n\n    \n      <h2>\n          APOE Statistics\n      <\/h2>\n\n\n<\/div>\n      \n          <\/div>\n  \n    \n      <div class=\"stats-container\">\n                          <div class=\"stat\">\n                \n                                    <span><p>Over 50% of Alzheimer\u2019s patients have the APOE \u03b54 gene variant<\/p>\n<\/span>\n                \n            <\/div>\n                                  <div class=\"stat\">\n                \n                                    <span><p>Having 2 copies of the APOE \u03b54 gene variant increases risk of Alzheimer\u2019s by 8- to 12-fold<\/p>\n<\/span>\n                \n            <\/div>\n                                  <div class=\"stat\">\n                \n                                    <span><p>15% to 25% of people are APOE \u03b54 carriers<\/p>\n<\/span>\n                \n            <\/div>\n                  <\/div>\n  \n\n  <\/div><\/div>\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-306\" src=\"https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/05\/volunteer2_mj-300x168.png\" alt=\"volunteer\" width=\"420\" height=\"235\" srcset=\"https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/05\/volunteer2_mj-300x168.png 300w, https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/05\/volunteer2_mj-1024x574.png 1024w, https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/05\/volunteer2_mj-768x432.png 768w, https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/05\/volunteer2_mj-320x180.png 320w, https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/05\/volunteer2_mj-1280x720.png 1280w, https:\/\/keck.usc.edu\/cpbh\/wp-content\/uploads\/sites\/154\/2024\/05\/volunteer2_mj.png 1456w\" sizes=\"auto, (max-width: 420px) 100vw, 420px\" \/><\/p>\n<h3>Visit our <a href=\"https:\/\/keck.usc.edu\/cpbh\/study-enrollment-hub\/\">Study Enrollment Hub<\/a> to learn how you can partner with us in the fight against Alzheimer&#8217;s disease!<\/h3>\n<p>&nbsp;<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":3,"featured_media":0,"parent":109,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"footnotes":""},"class_list":["post-116","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.2 (Yoast SEO v28.6) - 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